Incidental Mutation 'R6193:Plxnb1'
| ID |
502727 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb1
|
| Ensembl Gene |
ENSMUSG00000053646 |
| Gene Name |
plexin B1 |
| Synonyms |
2900002G15Rik |
| MMRRC Submission |
044333-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6193 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
108924457-108948985 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 108933971 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 733
(L733P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071966
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072093]
[ENSMUST00000130366]
[ENSMUST00000131462]
|
| AlphaFold |
Q8CJH3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000072093
AA Change: L733P
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000071966
Gene: ENSMUSG00000053646
AA Change: L733P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
35 |
463 |
5.84e-101 |
SMART |
|
PSI
|
481 |
534 |
1.17e-13 |
SMART |
|
PSI
|
628 |
678 |
6.97e-3 |
SMART |
|
low complexity region
|
691 |
706 |
N/A |
INTRINSIC |
|
low complexity region
|
752 |
771 |
N/A |
INTRINSIC |
|
PSI
|
1019 |
1066 |
2.06e-5 |
SMART |
|
IPT
|
1067 |
1158 |
7.48e-18 |
SMART |
|
IPT
|
1159 |
1247 |
3.97e-22 |
SMART |
|
IPT
|
1249 |
1359 |
6.09e-9 |
SMART |
|
low complexity region
|
1483 |
1494 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1546 |
2086 |
6.5e-230 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000130366
|
| SMART Domains |
Protein: ENSMUSP00000114358
Gene: ENSMUSG00000053646
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:Sema
|
35 |
138 |
7.5e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131462
|
| SMART Domains |
Protein: ENSMUSP00000115265
Gene: ENSMUSG00000053646
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:Sema
|
35 |
138 |
7.5e-11 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192117
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192988
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194734
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195364
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A1bg |
A |
G |
15: 60,792,629 (GRCm39) |
I106T |
probably benign |
Het |
| Aagab |
A |
C |
9: 63,524,795 (GRCm39) |
N35H |
possibly damaging |
Het |
| Abcf1 |
A |
C |
17: 36,274,464 (GRCm39) |
N161K |
possibly damaging |
Het |
| Adam11 |
T |
A |
11: 102,662,087 (GRCm39) |
H140Q |
probably benign |
Het |
| Araf |
G |
T |
X: 20,726,339 (GRCm39) |
R601L |
probably damaging |
Homo |
| Arhgef26 |
A |
T |
3: 62,247,213 (GRCm39) |
D99V |
possibly damaging |
Het |
| Arhgef28 |
A |
G |
13: 98,121,888 (GRCm39) |
S559P |
probably damaging |
Het |
| Capn11 |
A |
G |
17: 45,964,430 (GRCm39) |
|
probably null |
Het |
| Ccdc157 |
T |
C |
11: 4,101,912 (GRCm39) |
H3R |
probably damaging |
Het |
| Cd101 |
A |
G |
3: 100,927,778 (GRCm39) |
L101P |
probably damaging |
Het |
| Clca3a1 |
A |
G |
3: 144,464,993 (GRCm39) |
V80A |
possibly damaging |
Het |
| Cnot6 |
T |
A |
11: 49,570,850 (GRCm39) |
I381F |
probably benign |
Het |
| Cntn3 |
T |
A |
6: 102,185,092 (GRCm39) |
I675F |
probably benign |
Het |
| Cplx2 |
C |
T |
13: 54,527,406 (GRCm39) |
P97S |
probably damaging |
Het |
| Crtac1 |
T |
A |
19: 42,312,236 (GRCm39) |
E159V |
possibly damaging |
Het |
| Cyp27a1 |
A |
G |
1: 74,776,231 (GRCm39) |
I416V |
probably benign |
Het |
| Cyp2d37-ps |
T |
C |
15: 82,574,014 (GRCm39) |
|
noncoding transcript |
Het |
| Cyp2d9 |
A |
G |
15: 82,336,728 (GRCm39) |
T26A |
probably benign |
Het |
| Cyp2j7 |
T |
A |
4: 96,083,440 (GRCm39) |
R503S |
probably damaging |
Het |
| Dclk1 |
A |
T |
3: 55,424,292 (GRCm39) |
|
probably null |
Het |
| Dgkq |
A |
T |
5: 108,803,366 (GRCm39) |
C231* |
probably null |
Het |
| Dync1i1 |
T |
A |
6: 5,730,679 (GRCm39) |
M38K |
probably benign |
Het |
| Eif2ak4 |
C |
T |
2: 118,231,081 (GRCm39) |
|
probably benign |
Het |
| Ephx2 |
A |
T |
14: 66,326,961 (GRCm39) |
D411E |
probably benign |
Het |
| Ephx2 |
T |
G |
14: 66,349,669 (GRCm39) |
Q34P |
probably benign |
Het |
| Fer1l5 |
A |
T |
1: 36,448,517 (GRCm39) |
N1092Y |
probably benign |
Het |
| Fetub |
C |
T |
16: 22,751,081 (GRCm39) |
R143C |
probably damaging |
Het |
| Fzd4 |
A |
T |
7: 89,057,197 (GRCm39) |
K415* |
probably null |
Het |
| Gfi1 |
A |
T |
5: 107,869,397 (GRCm39) |
Y278N |
probably benign |
Het |
| Gm11565 |
T |
C |
11: 99,806,070 (GRCm39) |
M154T |
probably benign |
Het |
| Gm7247 |
A |
G |
14: 51,759,299 (GRCm39) |
I93V |
possibly damaging |
Het |
| Golm1 |
T |
G |
13: 59,792,972 (GRCm39) |
I178L |
probably benign |
Het |
| Grip1 |
A |
T |
10: 119,874,219 (GRCm39) |
D302V |
probably damaging |
Het |
| Gtf2h1 |
G |
A |
7: 46,456,254 (GRCm39) |
|
probably null |
Het |
| Herc2 |
C |
A |
7: 55,806,649 (GRCm39) |
P2372T |
probably damaging |
Het |
| Ighv1-59 |
C |
A |
12: 115,298,786 (GRCm39) |
L89F |
probably damaging |
Het |
| Ighv7-4 |
G |
A |
12: 114,186,445 (GRCm39) |
A109V |
possibly damaging |
Het |
| Kcnk10 |
G |
T |
12: 98,407,031 (GRCm39) |
Q222K |
probably benign |
Het |
| Klra6 |
A |
T |
6: 129,995,881 (GRCm39) |
M159K |
probably benign |
Het |
| Lzts3 |
T |
C |
2: 130,479,306 (GRCm39) |
T36A |
probably damaging |
Het |
| Mgam |
T |
A |
6: 40,724,854 (GRCm39) |
Y443* |
probably null |
Het |
| Mmp23 |
T |
A |
4: 155,735,990 (GRCm39) |
M221L |
possibly damaging |
Het |
| Mmp7 |
T |
A |
9: 7,695,519 (GRCm39) |
V132E |
probably damaging |
Het |
| Npas2 |
C |
A |
1: 39,331,843 (GRCm39) |
T86N |
probably damaging |
Het |
| Or1e32 |
T |
A |
11: 73,705,650 (GRCm39) |
H86L |
probably benign |
Het |
| Or5al7 |
C |
T |
2: 85,992,628 (GRCm39) |
V222M |
possibly damaging |
Het |
| Papola |
A |
T |
12: 105,786,605 (GRCm39) |
E103V |
probably benign |
Het |
| Parp9 |
A |
T |
16: 35,767,921 (GRCm39) |
N34Y |
possibly damaging |
Het |
| Pcdh7 |
A |
G |
5: 57,877,666 (GRCm39) |
D407G |
probably damaging |
Het |
| Pcdhb5 |
T |
G |
18: 37,455,080 (GRCm39) |
Y487D |
probably damaging |
Het |
| Pira12 |
C |
G |
7: 3,901,049 (GRCm39) |
|
probably null |
Het |
| Pla2g4a |
T |
C |
1: 149,778,181 (GRCm39) |
D5G |
probably damaging |
Het |
| Ppfia4 |
T |
C |
1: 134,251,899 (GRCm39) |
D425G |
probably benign |
Het |
| Prss2 |
T |
G |
6: 41,498,754 (GRCm39) |
I6S |
unknown |
Het |
| Psme3ip1 |
A |
G |
8: 95,302,348 (GRCm39) |
S228P |
probably damaging |
Het |
| Qrfprl |
T |
A |
6: 65,433,142 (GRCm39) |
F321I |
probably damaging |
Het |
| Qrich2 |
T |
A |
11: 116,344,979 (GRCm39) |
I1693L |
probably benign |
Het |
| Rad52 |
T |
C |
6: 119,897,143 (GRCm39) |
V324A |
probably benign |
Het |
| Rapgef2 |
A |
T |
3: 78,976,751 (GRCm39) |
Y1352N |
possibly damaging |
Het |
| Rsad2 |
T |
G |
12: 26,506,186 (GRCm39) |
Y78S |
probably damaging |
Het |
| Scaf1 |
A |
G |
7: 44,656,204 (GRCm39) |
|
probably benign |
Het |
| Sfxn5 |
T |
C |
6: 85,246,918 (GRCm39) |
T131A |
probably damaging |
Het |
| Slc4a10 |
T |
G |
2: 62,073,701 (GRCm39) |
|
probably null |
Het |
| Spmap2l |
A |
G |
5: 77,164,183 (GRCm39) |
D62G |
possibly damaging |
Het |
| Syt1 |
A |
G |
10: 108,336,597 (GRCm39) |
V357A |
probably benign |
Het |
| Tenm2 |
T |
A |
11: 35,937,621 (GRCm39) |
D1685V |
probably damaging |
Het |
| Tmc3 |
A |
G |
7: 83,252,543 (GRCm39) |
T315A |
probably benign |
Het |
| Tmem266 |
T |
C |
9: 55,344,493 (GRCm39) |
L375P |
probably benign |
Het |
| Tsks |
T |
G |
7: 44,603,263 (GRCm39) |
L355R |
probably damaging |
Het |
| Uaca |
G |
A |
9: 60,777,326 (GRCm39) |
R571Q |
probably damaging |
Het |
| Ube2f |
T |
A |
1: 91,203,041 (GRCm39) |
|
probably null |
Het |
| Usp37 |
A |
T |
1: 74,532,087 (GRCm39) |
V102D |
probably damaging |
Het |
| Usp44 |
G |
A |
10: 93,683,010 (GRCm39) |
|
probably benign |
Het |
| Vmn2r115 |
T |
C |
17: 23,575,983 (GRCm39) |
F527S |
probably benign |
Het |
| Zfp101 |
A |
C |
17: 33,600,720 (GRCm39) |
Y345* |
probably null |
Het |
| Zfp160 |
C |
A |
17: 21,247,124 (GRCm39) |
A558E |
probably benign |
Het |
| Zfp236 |
T |
C |
18: 82,622,372 (GRCm39) |
E1686G |
probably damaging |
Het |
| Zfp655 |
T |
A |
5: 145,181,586 (GRCm39) |
D481E |
probably benign |
Het |
| Zswim4 |
A |
G |
8: 84,952,774 (GRCm39) |
V396A |
probably benign |
Het |
|
| Other mutations in Plxnb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00593:Plxnb1
|
APN |
9 |
108,942,936 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01014:Plxnb1
|
APN |
9 |
108,935,102 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01142:Plxnb1
|
APN |
9 |
108,931,765 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01454:Plxnb1
|
APN |
9 |
108,942,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01469:Plxnb1
|
APN |
9 |
108,934,483 (GRCm39) |
intron |
probably benign |
|
|
IGL01530:Plxnb1
|
APN |
9 |
108,939,473 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01599:Plxnb1
|
APN |
9 |
108,939,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01968:Plxnb1
|
APN |
9 |
108,930,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02175:Plxnb1
|
APN |
9 |
108,929,914 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02216:Plxnb1
|
APN |
9 |
108,929,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Plxnb1
|
APN |
9 |
108,941,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02311:Plxnb1
|
APN |
9 |
108,930,190 (GRCm39) |
missense |
probably benign |
|
|
IGL02645:Plxnb1
|
APN |
9 |
108,943,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL03076:Plxnb1
|
APN |
9 |
108,935,970 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03107:Plxnb1
|
APN |
9 |
108,934,054 (GRCm39) |
missense |
probably benign |
|
|
IGL03343:Plxnb1
|
APN |
9 |
108,943,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4431001:Plxnb1
|
UTSW |
9 |
108,929,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0117:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0843:Plxnb1
|
UTSW |
9 |
108,942,769 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0970:Plxnb1
|
UTSW |
9 |
108,932,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Plxnb1
|
UTSW |
9 |
108,931,210 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1342:Plxnb1
|
UTSW |
9 |
108,929,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1386:Plxnb1
|
UTSW |
9 |
108,930,091 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1419:Plxnb1
|
UTSW |
9 |
108,943,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1445:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
probably null |
|
|
R1548:Plxnb1
|
UTSW |
9 |
108,929,968 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1621:Plxnb1
|
UTSW |
9 |
108,935,873 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1658:Plxnb1
|
UTSW |
9 |
108,931,939 (GRCm39) |
nonsense |
probably null |
|
|
R1727:Plxnb1
|
UTSW |
9 |
108,930,125 (GRCm39) |
splice site |
probably null |
|
|
R1750:Plxnb1
|
UTSW |
9 |
108,940,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1795:Plxnb1
|
UTSW |
9 |
108,929,813 (GRCm39) |
missense |
probably benign |
|
|
R1929:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R1935:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1936:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2014:Plxnb1
|
UTSW |
9 |
108,935,687 (GRCm39) |
splice site |
probably benign |
|
|
R2057:Plxnb1
|
UTSW |
9 |
108,938,294 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2102:Plxnb1
|
UTSW |
9 |
108,944,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R2422:Plxnb1
|
UTSW |
9 |
108,937,506 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2881:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3409:Plxnb1
|
UTSW |
9 |
108,935,681 (GRCm39) |
splice site |
probably null |
|
|
R3417:Plxnb1
|
UTSW |
9 |
108,929,828 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3756:Plxnb1
|
UTSW |
9 |
108,942,526 (GRCm39) |
unclassified |
probably benign |
|
|
R3788:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3789:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4042:Plxnb1
|
UTSW |
9 |
108,934,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4289:Plxnb1
|
UTSW |
9 |
108,943,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4396:Plxnb1
|
UTSW |
9 |
108,929,291 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4564:Plxnb1
|
UTSW |
9 |
108,942,488 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4676:Plxnb1
|
UTSW |
9 |
108,939,503 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4706:Plxnb1
|
UTSW |
9 |
108,941,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Plxnb1
|
UTSW |
9 |
108,939,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4796:Plxnb1
|
UTSW |
9 |
108,943,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4835:Plxnb1
|
UTSW |
9 |
108,934,442 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4901:Plxnb1
|
UTSW |
9 |
108,934,027 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4952:Plxnb1
|
UTSW |
9 |
108,943,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Plxnb1
|
UTSW |
9 |
108,935,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5015:Plxnb1
|
UTSW |
9 |
108,929,498 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5029:Plxnb1
|
UTSW |
9 |
108,943,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Plxnb1
|
UTSW |
9 |
108,940,761 (GRCm39) |
splice site |
probably null |
|
|
R5256:Plxnb1
|
UTSW |
9 |
108,943,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5285:Plxnb1
|
UTSW |
9 |
108,937,527 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5431:Plxnb1
|
UTSW |
9 |
108,929,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5444:Plxnb1
|
UTSW |
9 |
108,935,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5546:Plxnb1
|
UTSW |
9 |
108,929,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5852:Plxnb1
|
UTSW |
9 |
108,935,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5892:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6020:Plxnb1
|
UTSW |
9 |
108,945,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6177:Plxnb1
|
UTSW |
9 |
108,931,993 (GRCm39) |
splice site |
probably null |
|
|
R6274:Plxnb1
|
UTSW |
9 |
108,941,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6310:Plxnb1
|
UTSW |
9 |
108,938,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6404:Plxnb1
|
UTSW |
9 |
108,945,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6422:Plxnb1
|
UTSW |
9 |
108,937,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6479:Plxnb1
|
UTSW |
9 |
108,940,733 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6555:Plxnb1
|
UTSW |
9 |
108,937,473 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6646:Plxnb1
|
UTSW |
9 |
108,937,895 (GRCm39) |
missense |
probably benign |
|
|
R6648:Plxnb1
|
UTSW |
9 |
108,933,398 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6661:Plxnb1
|
UTSW |
9 |
108,933,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6674:Plxnb1
|
UTSW |
9 |
108,937,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6734:Plxnb1
|
UTSW |
9 |
108,937,988 (GRCm39) |
nonsense |
probably null |
|
|
R6859:Plxnb1
|
UTSW |
9 |
108,935,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6948:Plxnb1
|
UTSW |
9 |
108,945,702 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7030:Plxnb1
|
UTSW |
9 |
108,941,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Plxnb1
|
UTSW |
9 |
108,929,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7204:Plxnb1
|
UTSW |
9 |
108,929,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7428:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7443:Plxnb1
|
UTSW |
9 |
108,943,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7527:Plxnb1
|
UTSW |
9 |
108,929,929 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7645:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7680:Plxnb1
|
UTSW |
9 |
108,929,571 (GRCm39) |
nonsense |
probably null |
|
|
R7866:Plxnb1
|
UTSW |
9 |
108,929,525 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7898:Plxnb1
|
UTSW |
9 |
108,943,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7905:Plxnb1
|
UTSW |
9 |
108,938,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8092:Plxnb1
|
UTSW |
9 |
108,929,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Plxnb1
|
UTSW |
9 |
108,941,146 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8286:Plxnb1
|
UTSW |
9 |
108,935,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Plxnb1
|
UTSW |
9 |
108,938,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8987:Plxnb1
|
UTSW |
9 |
108,937,178 (GRCm39) |
splice site |
probably benign |
|
|
R9176:Plxnb1
|
UTSW |
9 |
108,941,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9698:Plxnb1
|
UTSW |
9 |
108,925,251 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTGCCTTAGAGAATTAACGGGATG -3'
(R):5'- AGCTGCATCTGAGGGGAATG -3'
Sequencing Primer
(F):5'- ACTTGCCTGCTGAGTGAC -3'
(R):5'- CTGCATCTGAGGGGAATGGGTAG -3'
|
| Posted On |
2018-02-27 |
Incidental Mutation