Incidental Mutation 'R6225:Cacna1i'
| ID |
504294 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cacna1i
|
| Ensembl Gene |
ENSMUSG00000022416 |
| Gene Name |
calcium channel, voltage-dependent, alpha 1I subunit |
| Synonyms |
|
| MMRRC Submission |
044356-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6225 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
80171439-80282480 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 80205427 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Valine
at position 128
(M128V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125229
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000160424]
[ENSMUST00000162155]
|
| AlphaFold |
E9Q7P2 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000160424
AA Change: M128V
PolyPhen 2
Score 0.578 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000125063
Gene: ENSMUSG00000022416
AA Change: M128V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
16 |
N/A |
INTRINSIC |
|
low complexity region
|
24 |
40 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
76 |
407 |
1.4e-79 |
PFAM |
|
low complexity region
|
464 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
531 |
554 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
597 |
830 |
7.4e-58 |
PFAM |
|
low complexity region
|
870 |
892 |
N/A |
INTRINSIC |
|
low complexity region
|
919 |
940 |
N/A |
INTRINSIC |
|
low complexity region
|
984 |
1015 |
N/A |
INTRINSIC |
|
low complexity region
|
1069 |
1080 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
1128 |
1401 |
7.8e-65 |
PFAM |
|
Pfam:Ion_trans
|
1445 |
1700 |
9.4e-58 |
PFAM |
|
Pfam:PKD_channel
|
1538 |
1694 |
1.4e-10 |
PFAM |
|
low complexity region
|
1718 |
1739 |
N/A |
INTRINSIC |
|
low complexity region
|
1744 |
1760 |
N/A |
INTRINSIC |
|
low complexity region
|
1837 |
1853 |
N/A |
INTRINSIC |
|
low complexity region
|
1922 |
1933 |
N/A |
INTRINSIC |
|
low complexity region
|
1990 |
2005 |
N/A |
INTRINSIC |
|
low complexity region
|
2041 |
2058 |
N/A |
INTRINSIC |
|
low complexity region
|
2087 |
2097 |
N/A |
INTRINSIC |
|
low complexity region
|
2103 |
2126 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000162155
AA Change: M128V
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000125229
Gene: ENSMUSG00000022416
AA Change: M128V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
16 |
N/A |
INTRINSIC |
|
low complexity region
|
24 |
40 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
115 |
395 |
1.9e-66 |
PFAM |
|
low complexity region
|
464 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
531 |
554 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
632 |
819 |
2.4e-45 |
PFAM |
|
low complexity region
|
870 |
892 |
N/A |
INTRINSIC |
|
low complexity region
|
919 |
940 |
N/A |
INTRINSIC |
|
low complexity region
|
984 |
1015 |
N/A |
INTRINSIC |
|
low complexity region
|
1069 |
1080 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
1165 |
1389 |
6.2e-55 |
PFAM |
|
coiled coil region
|
1394 |
1426 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
1480 |
1688 |
1.9e-47 |
PFAM |
|
Pfam:PKD_channel
|
1538 |
1694 |
4.8e-10 |
PFAM |
|
low complexity region
|
1718 |
1739 |
N/A |
INTRINSIC |
|
low complexity region
|
1744 |
1760 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.3921 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.3%
- 20x: 95.2%
|
| Validation Efficiency |
100% (74/74) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ace |
A |
G |
11: 105,870,445 (GRCm39) |
H288R |
possibly damaging |
Het |
| Adh1 |
T |
C |
3: 137,995,565 (GRCm39) |
F323L |
probably benign |
Het |
| Adss1 |
A |
C |
12: 112,600,837 (GRCm39) |
H226P |
probably damaging |
Het |
| Ahrr |
A |
G |
13: 74,371,031 (GRCm39) |
S230P |
possibly damaging |
Het |
| Akap9 |
T |
C |
5: 4,012,105 (GRCm39) |
V936A |
probably damaging |
Het |
| B4galnt2 |
A |
G |
11: 95,759,268 (GRCm39) |
Y339H |
probably damaging |
Het |
| Bltp1 |
T |
C |
3: 37,002,453 (GRCm39) |
V1466A |
probably damaging |
Het |
| C4b |
C |
A |
17: 34,957,848 (GRCm39) |
G611V |
possibly damaging |
Het |
| Chia1 |
T |
C |
3: 106,038,213 (GRCm39) |
S370P |
possibly damaging |
Het |
| Cops6 |
T |
C |
5: 138,159,673 (GRCm39) |
V9A |
possibly damaging |
Het |
| D630003M21Rik |
A |
T |
2: 158,059,321 (GRCm39) |
I193K |
probably benign |
Het |
| Daam2 |
T |
C |
17: 49,801,467 (GRCm39) |
D90G |
probably damaging |
Het |
| Fads3 |
A |
G |
19: 10,019,202 (GRCm39) |
D36G |
probably benign |
Het |
| Fam185a |
T |
C |
5: 21,630,554 (GRCm39) |
V130A |
probably damaging |
Het |
| Fbn1 |
A |
T |
2: 125,172,463 (GRCm39) |
N1928K |
probably damaging |
Het |
| Fstl3 |
A |
G |
10: 79,615,843 (GRCm39) |
M110V |
probably benign |
Het |
| G2e3 |
A |
G |
12: 51,415,919 (GRCm39) |
T552A |
possibly damaging |
Het |
| Gfra1 |
G |
A |
19: 58,226,830 (GRCm39) |
T462I |
probably damaging |
Het |
| Glrx2 |
T |
A |
1: 143,621,121 (GRCm39) |
|
probably benign |
Het |
| Gm10100 |
G |
T |
10: 77,562,498 (GRCm39) |
C60F |
possibly damaging |
Het |
| Gm43302 |
T |
A |
5: 105,425,605 (GRCm39) |
K275* |
probably null |
Het |
| Gm6569 |
A |
G |
15: 73,711,640 (GRCm39) |
|
probably benign |
Het |
| Herc6 |
G |
T |
6: 57,639,139 (GRCm39) |
V867L |
possibly damaging |
Het |
| Hhipl2 |
T |
A |
1: 183,209,459 (GRCm39) |
|
probably null |
Het |
| Kcnj16 |
A |
T |
11: 110,916,378 (GRCm39) |
K347* |
probably null |
Het |
| Kcnt2 |
T |
A |
1: 140,354,661 (GRCm39) |
C305* |
probably null |
Het |
| Large2 |
A |
G |
2: 92,196,825 (GRCm39) |
L477P |
probably damaging |
Het |
| Lnpep |
T |
C |
17: 17,799,245 (GRCm39) |
T137A |
possibly damaging |
Het |
| Mettl3 |
T |
C |
14: 52,534,215 (GRCm39) |
|
probably null |
Het |
| Mical3 |
C |
T |
6: 120,935,684 (GRCm39) |
S1614N |
probably damaging |
Het |
| Mmut |
T |
A |
17: 41,249,622 (GRCm39) |
V199E |
possibly damaging |
Het |
| Morc3 |
C |
A |
16: 93,642,082 (GRCm39) |
Y100* |
probably null |
Het |
| Mrc2 |
A |
G |
11: 105,237,646 (GRCm39) |
K1108R |
probably benign |
Het |
| Mrpl2 |
T |
C |
17: 46,960,835 (GRCm39) |
V243A |
probably damaging |
Het |
| Mtor |
T |
A |
4: 148,605,794 (GRCm39) |
N1505K |
probably benign |
Het |
| Myo1g |
A |
T |
11: 6,469,168 (GRCm39) |
Y45N |
probably damaging |
Het |
| Nckap5l |
C |
A |
15: 99,325,905 (GRCm39) |
L199F |
possibly damaging |
Het |
| Ndufc2 |
A |
G |
7: 97,056,099 (GRCm39) |
T66A |
probably damaging |
Het |
| Nos1 |
T |
A |
5: 118,050,917 (GRCm39) |
H779Q |
probably damaging |
Het |
| Or12e13 |
A |
G |
2: 87,663,661 (GRCm39) |
T93A |
probably benign |
Het |
| Or13j1 |
T |
C |
4: 43,705,698 (GRCm39) |
Y290C |
probably damaging |
Het |
| Or1e23 |
T |
C |
11: 73,407,831 (GRCm39) |
N65D |
probably damaging |
Het |
| Or4c3 |
A |
G |
2: 89,851,573 (GRCm39) |
|
probably null |
Het |
| Or51ah3 |
A |
T |
7: 103,210,489 (GRCm39) |
R268S |
probably benign |
Het |
| Or5au1 |
C |
A |
14: 52,272,825 (GRCm39) |
V248L |
possibly damaging |
Het |
| Or5k16 |
T |
C |
16: 58,736,545 (GRCm39) |
N153S |
probably benign |
Het |
| Otog |
C |
T |
7: 45,898,458 (GRCm39) |
T192I |
possibly damaging |
Het |
| Oxct1 |
T |
C |
15: 4,064,812 (GRCm39) |
V50A |
probably benign |
Het |
| P3h2 |
T |
A |
16: 25,784,493 (GRCm39) |
D667V |
probably damaging |
Het |
| Pcdhb20 |
A |
G |
18: 37,638,047 (GRCm39) |
Y191C |
probably damaging |
Het |
| Pds5b |
T |
G |
5: 150,670,083 (GRCm39) |
V357G |
probably damaging |
Het |
| Pggt1b |
A |
G |
18: 46,407,674 (GRCm39) |
V81A |
possibly damaging |
Het |
| Phxr2 |
A |
G |
10: 98,962,043 (GRCm39) |
|
probably benign |
Het |
| Pnpt1 |
T |
C |
11: 29,095,469 (GRCm39) |
I406T |
probably benign |
Het |
| Ppat |
T |
C |
5: 77,070,202 (GRCm39) |
I173V |
probably damaging |
Het |
| Proser3 |
T |
C |
7: 30,243,153 (GRCm39) |
S167G |
probably damaging |
Het |
| Rnf135 |
A |
C |
11: 80,080,053 (GRCm39) |
T115P |
possibly damaging |
Het |
| Rpl22 |
C |
T |
4: 152,414,536 (GRCm39) |
R65C |
probably benign |
Het |
| Scel |
T |
C |
14: 103,829,420 (GRCm39) |
F405L |
probably benign |
Het |
| Serinc3 |
A |
G |
2: 163,469,799 (GRCm39) |
Y350H |
probably damaging |
Het |
| Slc25a16 |
C |
A |
10: 62,764,102 (GRCm39) |
T53K |
probably damaging |
Het |
| Slco1a1 |
A |
T |
6: 141,870,215 (GRCm39) |
F308I |
possibly damaging |
Het |
| Slitrk5 |
GACTAC |
GACTACTAC |
14: 111,917,248 (GRCm39) |
|
probably benign |
Het |
| Smok3c |
T |
C |
5: 138,063,314 (GRCm39) |
V267A |
probably benign |
Het |
| Ssrp1 |
A |
G |
2: 84,873,158 (GRCm39) |
D473G |
probably benign |
Het |
| Svs6 |
A |
G |
2: 164,159,405 (GRCm39) |
E56G |
possibly damaging |
Het |
| Tas2r130 |
TCATTTC |
T |
6: 131,607,547 (GRCm39) |
|
probably benign |
Het |
| Thoc3 |
T |
C |
13: 54,615,785 (GRCm39) |
N93S |
probably benign |
Het |
| Tle6 |
A |
G |
10: 81,428,600 (GRCm39) |
C443R |
probably damaging |
Het |
| Tmed6 |
A |
G |
8: 107,788,371 (GRCm39) |
F192S |
probably damaging |
Het |
| Tpx2 |
A |
G |
2: 152,718,548 (GRCm39) |
N184D |
probably benign |
Het |
| Vmn2r31 |
T |
A |
7: 7,397,638 (GRCm39) |
N207Y |
probably benign |
Het |
| Zfp267 |
T |
C |
3: 36,220,352 (GRCm39) |
F792L |
probably benign |
Het |
| Zfp709 |
TCGACG |
TCG |
8: 72,644,552 (GRCm39) |
|
probably benign |
Het |
| Zfp972 |
A |
T |
2: 177,549,117 (GRCm39) |
|
probably null |
Het |
| Zzef1 |
G |
A |
11: 72,760,631 (GRCm39) |
C1318Y |
possibly damaging |
Het |
|
| Other mutations in Cacna1i |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00421:Cacna1i
|
APN |
15 |
80,266,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00976:Cacna1i
|
APN |
15 |
80,239,846 (GRCm39) |
missense |
probably benign |
|
|
IGL01338:Cacna1i
|
APN |
15 |
80,232,581 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01589:Cacna1i
|
APN |
15 |
80,271,960 (GRCm39) |
splice site |
probably benign |
|
|
IGL01669:Cacna1i
|
APN |
15 |
80,275,958 (GRCm39) |
missense |
probably benign |
|
|
IGL01807:Cacna1i
|
APN |
15 |
80,258,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01911:Cacna1i
|
APN |
15 |
80,275,933 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01973:Cacna1i
|
APN |
15 |
80,266,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02205:Cacna1i
|
APN |
15 |
80,257,152 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02519:Cacna1i
|
APN |
15 |
80,246,075 (GRCm39) |
nonsense |
probably null |
|
|
IGL02648:Cacna1i
|
APN |
15 |
80,182,839 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03033:Cacna1i
|
APN |
15 |
80,246,440 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03214:Cacna1i
|
APN |
15 |
80,239,917 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0067:Cacna1i
|
UTSW |
15 |
80,265,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0067:Cacna1i
|
UTSW |
15 |
80,265,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0295:Cacna1i
|
UTSW |
15 |
80,240,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0345:Cacna1i
|
UTSW |
15 |
80,256,663 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0415:Cacna1i
|
UTSW |
15 |
80,253,031 (GRCm39) |
splice site |
probably benign |
|
|
R0637:Cacna1i
|
UTSW |
15 |
80,256,855 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0638:Cacna1i
|
UTSW |
15 |
80,265,281 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0840:Cacna1i
|
UTSW |
15 |
80,243,150 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1463:Cacna1i
|
UTSW |
15 |
80,263,255 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1528:Cacna1i
|
UTSW |
15 |
80,275,975 (GRCm39) |
splice site |
probably null |
|
|
R1563:Cacna1i
|
UTSW |
15 |
80,274,056 (GRCm39) |
splice site |
probably benign |
|
|
R1563:Cacna1i
|
UTSW |
15 |
80,205,389 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1573:Cacna1i
|
UTSW |
15 |
80,277,869 (GRCm39) |
splice site |
probably null |
|
|
R1654:Cacna1i
|
UTSW |
15 |
80,273,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Cacna1i
|
UTSW |
15 |
80,255,730 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1794:Cacna1i
|
UTSW |
15 |
80,273,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1824:Cacna1i
|
UTSW |
15 |
80,260,990 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1863:Cacna1i
|
UTSW |
15 |
80,243,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1885:Cacna1i
|
UTSW |
15 |
80,243,145 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1886:Cacna1i
|
UTSW |
15 |
80,243,145 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1899:Cacna1i
|
UTSW |
15 |
80,275,843 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1907:Cacna1i
|
UTSW |
15 |
80,259,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1943:Cacna1i
|
UTSW |
15 |
80,279,245 (GRCm39) |
missense |
probably benign |
|
|
R2162:Cacna1i
|
UTSW |
15 |
80,240,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2888:Cacna1i
|
UTSW |
15 |
80,258,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3701:Cacna1i
|
UTSW |
15 |
80,265,272 (GRCm39) |
splice site |
probably benign |
|
|
R3702:Cacna1i
|
UTSW |
15 |
80,265,272 (GRCm39) |
splice site |
probably benign |
|
|
R3832:Cacna1i
|
UTSW |
15 |
80,240,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4852:Cacna1i
|
UTSW |
15 |
80,272,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4857:Cacna1i
|
UTSW |
15 |
80,253,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4950:Cacna1i
|
UTSW |
15 |
80,252,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4980:Cacna1i
|
UTSW |
15 |
80,232,650 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5217:Cacna1i
|
UTSW |
15 |
80,275,041 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5437:Cacna1i
|
UTSW |
15 |
80,255,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5519:Cacna1i
|
UTSW |
15 |
80,255,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5642:Cacna1i
|
UTSW |
15 |
80,279,279 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R6217:Cacna1i
|
UTSW |
15 |
80,273,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6251:Cacna1i
|
UTSW |
15 |
80,220,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6463:Cacna1i
|
UTSW |
15 |
80,239,959 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6490:Cacna1i
|
UTSW |
15 |
80,262,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6613:Cacna1i
|
UTSW |
15 |
80,205,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6884:Cacna1i
|
UTSW |
15 |
80,259,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6904:Cacna1i
|
UTSW |
15 |
80,259,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7017:Cacna1i
|
UTSW |
15 |
80,264,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7155:Cacna1i
|
UTSW |
15 |
80,279,439 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7274:Cacna1i
|
UTSW |
15 |
80,261,023 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7323:Cacna1i
|
UTSW |
15 |
80,275,854 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7335:Cacna1i
|
UTSW |
15 |
80,259,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7571:Cacna1i
|
UTSW |
15 |
80,259,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7768:Cacna1i
|
UTSW |
15 |
80,265,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7820:Cacna1i
|
UTSW |
15 |
80,256,573 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7987:Cacna1i
|
UTSW |
15 |
80,204,553 (GRCm39) |
splice site |
probably null |
|
|
R8150:Cacna1i
|
UTSW |
15 |
80,259,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8206:Cacna1i
|
UTSW |
15 |
80,274,016 (GRCm39) |
splice site |
probably null |
|
|
R8270:Cacna1i
|
UTSW |
15 |
80,257,835 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8382:Cacna1i
|
UTSW |
15 |
80,261,017 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8501:Cacna1i
|
UTSW |
15 |
80,266,247 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8518:Cacna1i
|
UTSW |
15 |
80,243,095 (GRCm39) |
nonsense |
probably null |
|
|
R8552:Cacna1i
|
UTSW |
15 |
80,204,598 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R8679:Cacna1i
|
UTSW |
15 |
80,260,011 (GRCm39) |
intron |
probably benign |
|
|
R8696:Cacna1i
|
UTSW |
15 |
80,266,175 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8887:Cacna1i
|
UTSW |
15 |
80,258,894 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9274:Cacna1i
|
UTSW |
15 |
80,254,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9379:Cacna1i
|
UTSW |
15 |
80,259,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9508:Cacna1i
|
UTSW |
15 |
80,279,372 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9518:Cacna1i
|
UTSW |
15 |
80,271,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9674:Cacna1i
|
UTSW |
15 |
80,264,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9747:Cacna1i
|
UTSW |
15 |
80,246,318 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9769:Cacna1i
|
UTSW |
15 |
80,253,793 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0022:Cacna1i
|
UTSW |
15 |
80,246,163 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0024:Cacna1i
|
UTSW |
15 |
80,246,340 (GRCm39) |
missense |
probably benign |
0.03 |
|
X0058:Cacna1i
|
UTSW |
15 |
80,263,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Cacna1i
|
UTSW |
15 |
80,273,584 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Z1177:Cacna1i
|
UTSW |
15 |
80,265,380 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATGAGCAGAATGGGCTGTG -3'
(R):5'- ATCTACAGGGAGCGTTGTCTC -3'
Sequencing Primer
(F):5'- AATGGGCTGTGGAACCCTG -3'
(R):5'- CAGGGAGCGTTGTCTCTCTGAC -3'
|
| Posted On |
2018-02-28 |
Incidental Mutation