Incidental Mutation 'R6244:Magi3'
| ID |
505432 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Magi3
|
| Ensembl Gene |
ENSMUSG00000052539 |
| Gene Name |
membrane associated guanylate kinase, WW and PDZ domain containing 3 |
| Synonyms |
4732496O19Rik, 6530407C02Rik |
| MMRRC Submission |
044435-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.435)
|
| Stock # |
R6244 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
103920575-104127690 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to C
at 103923013 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Aspartic acid
at position 1235
(H1235D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112934
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064371]
[ENSMUST00000121198]
[ENSMUST00000122303]
[ENSMUST00000145727]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064371
|
| SMART Domains |
Protein: ENSMUSP00000067932
Gene: ENSMUSG00000052539
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000121198
AA Change: H1235D
PolyPhen 2
Score 0.160 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000112934
Gene: ENSMUSG00000052539
AA Change: H1235D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122303
|
| SMART Domains |
Protein: ENSMUSP00000113713
Gene: ENSMUSG00000052539
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145727
|
| SMART Domains |
Protein: ENSMUSP00000114722
Gene: ENSMUSG00000058388
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Phtf-FEM1B_bdg
|
3 |
158 |
1.6e-88 |
PFAM |
|
low complexity region
|
170 |
181 |
N/A |
INTRINSIC |
|
low complexity region
|
347 |
370 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
512 |
534 |
N/A |
INTRINSIC |
|
transmembrane domain
|
610 |
632 |
N/A |
INTRINSIC |
|
transmembrane domain
|
647 |
664 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0826 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.3%
- 20x: 95.1%
|
| Validation Efficiency |
96% (82/85) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 6430550D23Rik |
T |
C |
2: 155,845,150 (GRCm39) |
H113R |
possibly damaging |
Het |
| Adgrf3 |
A |
T |
5: 30,402,531 (GRCm39) |
M499K |
probably benign |
Het |
| Adgrv1 |
G |
A |
13: 81,255,050 (GRCm39) |
T211I |
probably damaging |
Het |
| Adss2 |
C |
T |
1: 177,604,395 (GRCm39) |
E153K |
probably benign |
Het |
| Ago4 |
C |
A |
4: 126,405,280 (GRCm39) |
G431V |
possibly damaging |
Het |
| Araf |
G |
T |
X: 20,726,339 (GRCm39) |
R601L |
probably damaging |
Homo |
| Atp2b4 |
T |
A |
1: 133,654,299 (GRCm39) |
I769F |
probably damaging |
Het |
| Atp9a |
T |
C |
2: 168,531,272 (GRCm39) |
|
probably null |
Het |
| Bltp1 |
T |
C |
3: 37,011,148 (GRCm39) |
V1782A |
probably benign |
Het |
| Brap |
C |
A |
5: 121,803,372 (GRCm39) |
D173E |
probably benign |
Het |
| Brca2 |
G |
T |
5: 150,490,443 (GRCm39) |
R3035L |
probably benign |
Het |
| Ccdc8 |
C |
A |
7: 16,730,176 (GRCm39) |
P555Q |
probably benign |
Het |
| Ccser2 |
A |
G |
14: 36,662,675 (GRCm39) |
S170P |
probably benign |
Het |
| Celsr2 |
T |
C |
3: 108,300,444 (GRCm39) |
H860R |
probably damaging |
Het |
| Cenpc1 |
C |
A |
5: 86,194,244 (GRCm39) |
R174M |
probably damaging |
Het |
| Cfap57 |
T |
G |
4: 118,436,607 (GRCm39) |
I930L |
probably damaging |
Het |
| Cx3cr1 |
C |
T |
9: 119,880,760 (GRCm39) |
R214H |
probably damaging |
Het |
| Cyp4f14 |
T |
A |
17: 33,125,291 (GRCm39) |
H429L |
probably benign |
Het |
| D5Ertd579e |
A |
G |
5: 36,772,620 (GRCm39) |
F592L |
probably damaging |
Het |
| Ddb1 |
A |
G |
19: 10,603,287 (GRCm39) |
E865G |
probably damaging |
Het |
| Ddx50 |
A |
T |
10: 62,457,345 (GRCm39) |
|
probably null |
Het |
| Dpp6 |
A |
G |
5: 27,254,626 (GRCm39) |
T14A |
probably damaging |
Het |
| Echs1 |
C |
A |
7: 139,692,982 (GRCm39) |
Q51H |
possibly damaging |
Het |
| Ecm2 |
A |
T |
13: 49,683,783 (GRCm39) |
D587V |
probably damaging |
Het |
| Ect2l |
A |
T |
10: 18,016,145 (GRCm39) |
Y666N |
possibly damaging |
Het |
| Epha2 |
G |
A |
4: 141,044,223 (GRCm39) |
G342S |
probably benign |
Het |
| Fbxo33 |
C |
A |
12: 59,252,865 (GRCm39) |
K211N |
probably benign |
Het |
| Fchsd2 |
A |
G |
7: 100,908,983 (GRCm39) |
|
probably null |
Het |
| Fen1 |
A |
G |
19: 10,178,051 (GRCm39) |
V131A |
probably damaging |
Het |
| Fetub |
C |
T |
16: 22,751,081 (GRCm39) |
R143C |
probably damaging |
Het |
| Flnb |
A |
G |
14: 7,892,092 (GRCm38) |
E587G |
probably damaging |
Het |
| Foxd3 |
A |
G |
4: 99,545,477 (GRCm39) |
T206A |
possibly damaging |
Het |
| Fut1 |
A |
G |
7: 45,268,730 (GRCm39) |
E228G |
possibly damaging |
Het |
| Galnt13 |
T |
C |
2: 54,823,560 (GRCm39) |
F379L |
probably damaging |
Het |
| Gcnt2 |
A |
C |
13: 41,014,717 (GRCm39) |
E296A |
probably damaging |
Het |
| Gm7145 |
T |
A |
1: 117,913,870 (GRCm39) |
C251S |
probably damaging |
Het |
| Gpam |
G |
A |
19: 55,059,417 (GRCm39) |
P810L |
probably damaging |
Het |
| Il1rl2 |
T |
A |
1: 40,366,726 (GRCm39) |
L87M |
possibly damaging |
Het |
| Itgae |
A |
G |
11: 73,036,427 (GRCm39) |
S1122G |
probably damaging |
Het |
| Kcnh7 |
T |
A |
2: 63,012,570 (GRCm39) |
D46V |
probably damaging |
Het |
| Kcnn3 |
T |
G |
3: 89,552,830 (GRCm39) |
Y511* |
probably null |
Het |
| Kdm3b |
T |
A |
18: 34,926,058 (GRCm39) |
I66N |
probably damaging |
Het |
| Klk1b27 |
A |
T |
7: 43,703,974 (GRCm39) |
H39L |
probably benign |
Het |
| Kmo |
C |
T |
1: 175,487,261 (GRCm39) |
T404I |
possibly damaging |
Het |
| Krt222 |
C |
T |
11: 99,125,884 (GRCm39) |
|
probably null |
Het |
| Mapk8ip1 |
C |
A |
2: 92,219,589 (GRCm39) |
G81C |
probably damaging |
Het |
| Med15 |
G |
A |
16: 17,470,609 (GRCm39) |
Q583* |
probably null |
Het |
| Mroh2a |
T |
C |
1: 88,184,476 (GRCm39) |
V1453A |
probably benign |
Het |
| Myh13 |
A |
G |
11: 67,253,327 (GRCm39) |
M1488V |
probably benign |
Het |
| Naip2 |
A |
T |
13: 100,288,645 (GRCm39) |
F1193L |
probably damaging |
Het |
| Nop58 |
T |
A |
1: 59,742,014 (GRCm39) |
M181K |
probably damaging |
Het |
| Npepps |
A |
T |
11: 97,104,616 (GRCm39) |
V796D |
probably damaging |
Het |
| Nr1d1 |
A |
G |
11: 98,661,363 (GRCm39) |
F301S |
probably damaging |
Het |
| Nynrin |
G |
A |
14: 56,105,485 (GRCm39) |
V832I |
probably damaging |
Het |
| Or13a28 |
C |
A |
7: 140,218,346 (GRCm39) |
S244Y |
probably damaging |
Het |
| Or1j14 |
T |
A |
2: 36,418,353 (GRCm39) |
C310S |
probably benign |
Het |
| Or2ak7 |
A |
T |
11: 58,574,830 (GRCm39) |
T44S |
possibly damaging |
Het |
| Or4e1 |
T |
A |
14: 52,701,352 (GRCm39) |
Y38F |
probably damaging |
Het |
| Or8k1 |
T |
A |
2: 86,047,566 (GRCm39) |
T163S |
possibly damaging |
Het |
| Phrf1 |
T |
A |
7: 140,817,586 (GRCm39) |
C132S |
probably damaging |
Het |
| Plekhn1 |
T |
C |
4: 156,315,015 (GRCm39) |
|
probably null |
Het |
| Polr2a |
G |
A |
11: 69,635,052 (GRCm39) |
T569M |
probably damaging |
Het |
| Prr29 |
A |
G |
11: 106,267,458 (GRCm39) |
|
probably null |
Het |
| Rsf1 |
CG |
CGACGGCGGAG |
7: 97,229,115 (GRCm39) |
|
probably benign |
Homo |
| Sc5d |
T |
C |
9: 42,166,717 (GRCm39) |
E274G |
probably benign |
Het |
| Serpina1d |
A |
T |
12: 103,731,087 (GRCm39) |
|
probably null |
Het |
| Serpinb11 |
T |
A |
1: 107,299,972 (GRCm39) |
I106N |
probably damaging |
Het |
| Setd2 |
G |
A |
9: 110,377,733 (GRCm39) |
R516K |
probably damaging |
Het |
| Sirt2 |
G |
T |
7: 28,487,222 (GRCm39) |
C291F |
probably damaging |
Het |
| Stac3 |
T |
C |
10: 127,344,044 (GRCm39) |
V314A |
probably damaging |
Het |
| Stat6 |
C |
T |
10: 127,493,581 (GRCm39) |
|
probably null |
Het |
| Strn3 |
A |
G |
12: 51,656,890 (GRCm39) |
V712A |
probably damaging |
Het |
| Tmc5 |
G |
T |
7: 118,233,437 (GRCm39) |
G84C |
possibly damaging |
Het |
| Tnik |
C |
A |
3: 28,704,328 (GRCm39) |
L996I |
probably damaging |
Het |
| Trim30d |
G |
T |
7: 104,136,817 (GRCm39) |
T129K |
probably damaging |
Het |
| Triml1 |
G |
T |
8: 43,591,793 (GRCm39) |
Y188* |
probably null |
Het |
| Trpc7 |
A |
G |
13: 56,921,705 (GRCm39) |
Y760H |
probably damaging |
Het |
| Uaca |
G |
A |
9: 60,777,326 (GRCm39) |
R571Q |
probably damaging |
Het |
| Ubash3a |
A |
T |
17: 31,458,246 (GRCm39) |
Q575L |
possibly damaging |
Het |
| Usp49 |
T |
A |
17: 47,983,827 (GRCm39) |
C61* |
probably null |
Het |
| Vmn2r18 |
A |
T |
5: 151,508,116 (GRCm39) |
V336E |
probably damaging |
Het |
| Vwa8 |
T |
C |
14: 79,324,102 (GRCm39) |
V1135A |
probably benign |
Het |
| Zcchc4 |
T |
C |
5: 52,940,503 (GRCm39) |
V24A |
probably benign |
Het |
| Zfp354c |
A |
G |
11: 50,705,798 (GRCm39) |
Y426H |
probably benign |
Het |
|
| Other mutations in Magi3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00429:Magi3
|
APN |
3 |
103,922,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00933:Magi3
|
APN |
3 |
103,923,163 (GRCm39) |
missense |
probably benign |
|
|
IGL01151:Magi3
|
APN |
3 |
103,958,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01674:Magi3
|
APN |
3 |
104,013,037 (GRCm39) |
splice site |
probably benign |
|
|
IGL01790:Magi3
|
APN |
3 |
103,992,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01903:Magi3
|
APN |
3 |
103,958,526 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01939:Magi3
|
APN |
3 |
103,961,778 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02142:Magi3
|
APN |
3 |
103,923,219 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02183:Magi3
|
APN |
3 |
103,992,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02887:Magi3
|
APN |
3 |
104,002,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03071:Magi3
|
APN |
3 |
103,923,202 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03085:Magi3
|
APN |
3 |
103,922,655 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL03192:Magi3
|
APN |
3 |
103,950,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Magi3
|
APN |
3 |
104,013,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03227:Magi3
|
APN |
3 |
103,958,435 (GRCm39) |
missense |
probably benign |
|
|
IGL03388:Magi3
|
APN |
3 |
103,923,157 (GRCm39) |
missense |
probably benign |
0.30 |
|
PIT4280001:Magi3
|
UTSW |
3 |
103,961,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4504001:Magi3
|
UTSW |
3 |
103,922,842 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0092:Magi3
|
UTSW |
3 |
103,958,280 (GRCm39) |
nonsense |
probably null |
|
|
R0514:Magi3
|
UTSW |
3 |
103,922,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0569:Magi3
|
UTSW |
3 |
103,923,358 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0608:Magi3
|
UTSW |
3 |
103,924,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0920:Magi3
|
UTSW |
3 |
103,941,507 (GRCm39) |
splice site |
probably null |
|
|
R1173:Magi3
|
UTSW |
3 |
103,968,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1256:Magi3
|
UTSW |
3 |
103,935,126 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1391:Magi3
|
UTSW |
3 |
103,922,374 (GRCm39) |
nonsense |
probably null |
|
|
R1559:Magi3
|
UTSW |
3 |
103,954,169 (GRCm39) |
splice site |
probably benign |
|
|
R1568:Magi3
|
UTSW |
3 |
103,996,843 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1631:Magi3
|
UTSW |
3 |
103,958,493 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1747:Magi3
|
UTSW |
3 |
103,941,489 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1930:Magi3
|
UTSW |
3 |
103,996,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1964:Magi3
|
UTSW |
3 |
103,927,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2151:Magi3
|
UTSW |
3 |
103,992,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2151:Magi3
|
UTSW |
3 |
103,954,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2266:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2267:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2268:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2519:Magi3
|
UTSW |
3 |
103,923,081 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3104:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3105:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3619:Magi3
|
UTSW |
3 |
103,961,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4158:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4160:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4284:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4285:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Magi3
|
UTSW |
3 |
104,127,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4512:Magi3
|
UTSW |
3 |
103,996,871 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4676:Magi3
|
UTSW |
3 |
103,923,141 (GRCm39) |
missense |
probably benign |
|
|
R4758:Magi3
|
UTSW |
3 |
103,922,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4940:Magi3
|
UTSW |
3 |
103,958,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Magi3
|
UTSW |
3 |
104,013,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5160:Magi3
|
UTSW |
3 |
103,935,224 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5422:Magi3
|
UTSW |
3 |
103,958,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Magi3
|
UTSW |
3 |
103,922,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5839:Magi3
|
UTSW |
3 |
104,127,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Magi3
|
UTSW |
3 |
103,961,854 (GRCm39) |
splice site |
probably null |
|
|
R6018:Magi3
|
UTSW |
3 |
104,013,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Magi3
|
UTSW |
3 |
103,958,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6235:Magi3
|
UTSW |
3 |
103,923,384 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6258:Magi3
|
UTSW |
3 |
103,996,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6358:Magi3
|
UTSW |
3 |
103,958,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6534:Magi3
|
UTSW |
3 |
103,992,536 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6806:Magi3
|
UTSW |
3 |
103,954,285 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6816:Magi3
|
UTSW |
3 |
103,997,227 (GRCm39) |
splice site |
probably null |
|
|
R6897:Magi3
|
UTSW |
3 |
103,996,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7011:Magi3
|
UTSW |
3 |
104,013,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7039:Magi3
|
UTSW |
3 |
103,958,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7196:Magi3
|
UTSW |
3 |
103,956,484 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7237:Magi3
|
UTSW |
3 |
103,935,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7285:Magi3
|
UTSW |
3 |
103,941,430 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7709:Magi3
|
UTSW |
3 |
103,941,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Magi3
|
UTSW |
3 |
103,923,243 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7797:Magi3
|
UTSW |
3 |
103,958,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7950:Magi3
|
UTSW |
3 |
103,924,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8140:Magi3
|
UTSW |
3 |
103,941,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8204:Magi3
|
UTSW |
3 |
103,958,502 (GRCm39) |
missense |
probably benign |
|
|
R8229:Magi3
|
UTSW |
3 |
103,923,018 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8229:Magi3
|
UTSW |
3 |
103,923,017 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R8260:Magi3
|
UTSW |
3 |
103,922,625 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8348:Magi3
|
UTSW |
3 |
103,958,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8368:Magi3
|
UTSW |
3 |
104,002,379 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8543:Magi3
|
UTSW |
3 |
104,126,984 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8762:Magi3
|
UTSW |
3 |
103,958,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Magi3
|
UTSW |
3 |
103,992,662 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8847:Magi3
|
UTSW |
3 |
103,922,334 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8892:Magi3
|
UTSW |
3 |
103,958,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8939:Magi3
|
UTSW |
3 |
103,996,748 (GRCm39) |
intron |
probably benign |
|
|
R9090:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9187:Magi3
|
UTSW |
3 |
103,923,073 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9271:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9433:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9439:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9557:Magi3
|
UTSW |
3 |
103,924,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9557:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9697:Magi3
|
UTSW |
3 |
103,956,458 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9796:Magi3
|
UTSW |
3 |
103,928,291 (GRCm39) |
missense |
probably benign |
|
|
X0026:Magi3
|
UTSW |
3 |
103,927,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGCCTCTGATAATTTGCCTTCAG -3'
(R):5'- TAAATGGAAGCCAGCCTGAG -3'
Sequencing Primer
(F):5'- GCCTTCAGTGTTTGACAGGC -3'
(R):5'- CCTGAGATGAAGTATCAGTCTGTCC -3'
|
| Posted On |
2018-02-28 |
Incidental Mutation