Incidental Mutation 'R6248:Myom2'
| ID |
505608 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myom2
|
| Ensembl Gene |
ENSMUSG00000031461 |
| Gene Name |
myomesin 2 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.148)
|
| Stock # |
R6248 (G1)
|
| Quality Score |
209.009 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
15107653-15183410 bp(+) (GRCm39) |
| Type of Mutation |
splice site (3 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 15148472 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033842
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033842]
|
| AlphaFold |
Q14BI5 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000033842
|
| SMART Domains |
Protein: ENSMUSP00000033842
Gene: ENSMUSG00000031461
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
63 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
87 |
N/A |
INTRINSIC |
|
coiled coil region
|
97 |
129 |
N/A |
INTRINSIC |
|
IG
|
160 |
247 |
7.7e-5 |
SMART |
|
IG
|
284 |
373 |
8.01e-3 |
SMART |
|
FN3
|
383 |
466 |
1.5e-14 |
SMART |
|
FN3
|
511 |
594 |
1.79e-12 |
SMART |
|
FN3
|
612 |
693 |
1.95e-13 |
SMART |
|
FN3
|
711 |
794 |
8.69e-11 |
SMART |
|
FN3
|
813 |
896 |
1.86e-10 |
SMART |
|
IG_like
|
913 |
999 |
1.58e2 |
SMART |
|
Blast:IG_like
|
1021 |
1106 |
1e-44 |
BLAST |
|
IG_like
|
1135 |
1215 |
2.27e1 |
SMART |
|
Blast:IG_like
|
1227 |
1321 |
9e-51 |
BLAST |
|
IGc2
|
1357 |
1425 |
4.96e-8 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000117573
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.0%
- 20x: 94.2%
|
| Validation Efficiency |
100% (92/92) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930523C07Rik |
T |
C |
1: 159,902,978 (GRCm39) |
S83P |
possibly damaging |
Het |
| Actr10 |
A |
T |
12: 70,999,733 (GRCm39) |
E176D |
probably benign |
Het |
| Adcy3 |
G |
A |
12: 4,258,662 (GRCm39) |
|
probably null |
Het |
| AI429214 |
T |
A |
8: 37,461,278 (GRCm39) |
I142N |
probably damaging |
Het |
| Alox12 |
A |
G |
11: 70,143,936 (GRCm39) |
L148S |
probably damaging |
Het |
| Ank3 |
A |
G |
10: 69,809,680 (GRCm39) |
I1147V |
probably benign |
Het |
| Apoc2 |
C |
T |
7: 19,407,493 (GRCm39) |
V12I |
probably benign |
Het |
| Arap3 |
T |
C |
18: 38,124,407 (GRCm39) |
S311G |
probably benign |
Het |
| Arih2 |
G |
T |
9: 108,488,841 (GRCm39) |
H292Q |
probably damaging |
Het |
| Cdc14a |
A |
T |
3: 116,101,843 (GRCm39) |
D312E |
probably benign |
Het |
| Cdh12 |
T |
G |
15: 21,237,800 (GRCm39) |
W12G |
possibly damaging |
Het |
| Cisd2 |
A |
T |
3: 135,114,616 (GRCm39) |
N118K |
probably damaging |
Het |
| Cntnap5b |
A |
G |
1: 99,999,827 (GRCm39) |
Q195R |
probably benign |
Het |
| Cyp2r1 |
A |
G |
7: 114,161,966 (GRCm39) |
|
probably null |
Het |
| Cyp4f37 |
A |
G |
17: 32,848,864 (GRCm39) |
D244G |
possibly damaging |
Het |
| Dab1 |
C |
T |
4: 104,588,948 (GRCm39) |
A524V |
probably benign |
Het |
| Dido1 |
T |
A |
2: 180,302,048 (GRCm39) |
H1952L |
probably damaging |
Het |
| Dnah10 |
T |
A |
5: 124,871,283 (GRCm39) |
|
probably null |
Het |
| Dnal4 |
T |
A |
15: 79,646,714 (GRCm39) |
M56L |
probably damaging |
Het |
| Emilin2 |
A |
G |
17: 71,581,112 (GRCm39) |
V538A |
probably benign |
Het |
| Eps8l2 |
A |
G |
7: 140,922,015 (GRCm39) |
D31G |
probably damaging |
Het |
| Erp44 |
A |
T |
4: 48,219,479 (GRCm39) |
L112* |
probably null |
Het |
| Etl4 |
C |
T |
2: 20,813,900 (GRCm39) |
T1907I |
possibly damaging |
Het |
| Exoc3 |
A |
G |
13: 74,330,400 (GRCm39) |
F510L |
probably benign |
Het |
| Fam114a2 |
G |
T |
11: 57,383,942 (GRCm39) |
T324K |
possibly damaging |
Het |
| Fer1l4 |
G |
A |
2: 155,888,091 (GRCm39) |
R465C |
probably damaging |
Het |
| Frmd4b |
A |
C |
6: 97,436,173 (GRCm39) |
S2R |
probably benign |
Het |
| Fscn1 |
A |
T |
5: 142,946,778 (GRCm39) |
D192V |
possibly damaging |
Het |
| Gm3486 |
T |
A |
14: 41,206,472 (GRCm39) |
*200C |
probably null |
Het |
| Gusb |
A |
T |
5: 130,029,366 (GRCm39) |
H138Q |
probably benign |
Het |
| Hdac9 |
A |
T |
12: 34,578,293 (GRCm39) |
M4K |
possibly damaging |
Het |
| Hhipl1 |
G |
T |
12: 108,284,964 (GRCm39) |
R439L |
probably benign |
Het |
| Hoxd9 |
A |
G |
2: 74,528,980 (GRCm39) |
E194G |
probably benign |
Het |
| Itgb1 |
A |
G |
8: 129,448,902 (GRCm39) |
S503G |
possibly damaging |
Het |
| Kcnt2 |
T |
A |
1: 140,437,216 (GRCm39) |
C500S |
probably damaging |
Het |
| Kdm7a |
G |
A |
6: 39,123,983 (GRCm39) |
S727L |
possibly damaging |
Het |
| Klhdc4 |
A |
G |
8: 122,540,507 (GRCm39) |
F92L |
probably damaging |
Het |
| Klrb1a |
A |
G |
6: 128,596,137 (GRCm39) |
V62A |
probably damaging |
Het |
| Krit1 |
A |
G |
5: 3,863,032 (GRCm39) |
|
probably null |
Het |
| Krt40 |
A |
G |
11: 99,432,566 (GRCm39) |
I150T |
possibly damaging |
Het |
| Larp4b |
A |
G |
13: 9,208,738 (GRCm39) |
T464A |
probably benign |
Het |
| Lrrc52 |
T |
G |
1: 167,293,964 (GRCm39) |
D107A |
probably damaging |
Het |
| Mapkap1 |
G |
T |
2: 34,408,692 (GRCm39) |
V35F |
probably damaging |
Het |
| Mccc1 |
A |
G |
3: 36,044,313 (GRCm39) |
V171A |
probably damaging |
Het |
| Metap1d |
A |
T |
2: 71,346,104 (GRCm39) |
R222* |
probably null |
Het |
| Mrgpre |
G |
A |
7: 143,334,603 (GRCm39) |
A300V |
probably benign |
Het |
| Mterf1b |
C |
A |
5: 4,246,606 (GRCm39) |
N82K |
probably benign |
Het |
| Myh9 |
C |
T |
15: 77,669,422 (GRCm39) |
W533* |
probably null |
Het |
| Ncor1 |
G |
A |
11: 62,257,808 (GRCm39) |
P329S |
probably damaging |
Het |
| Nr2f1 |
T |
C |
13: 78,344,611 (GRCm39) |
|
probably benign |
Het |
| Or10x1 |
T |
G |
1: 174,197,236 (GRCm39) |
V251G |
probably benign |
Het |
| Or11a4 |
T |
A |
17: 37,536,451 (GRCm39) |
L145* |
probably null |
Het |
| Or2a57 |
C |
T |
6: 43,212,838 (GRCm39) |
Q99* |
probably null |
Het |
| Or2w6 |
A |
T |
13: 21,843,244 (GRCm39) |
I83N |
possibly damaging |
Het |
| Or52p2 |
T |
C |
7: 102,237,237 (GRCm39) |
T238A |
probably benign |
Het |
| Or6c210 |
A |
G |
10: 129,496,532 (GRCm39) |
I286V |
probably benign |
Het |
| Or6z1 |
A |
T |
7: 6,504,675 (GRCm39) |
C183* |
probably null |
Het |
| Pcdha11 |
T |
C |
18: 37,138,950 (GRCm39) |
L193P |
probably benign |
Het |
| Pcdhb20 |
T |
A |
18: 37,639,285 (GRCm39) |
F604I |
probably damaging |
Het |
| Pde1a |
T |
C |
2: 79,708,545 (GRCm39) |
H291R |
probably damaging |
Het |
| Pfkm |
G |
A |
15: 98,024,260 (GRCm39) |
V423M |
probably damaging |
Het |
| Pira1 |
C |
A |
7: 3,739,337 (GRCm39) |
E510D |
probably benign |
Het |
| Pkd2l1 |
G |
T |
19: 44,146,108 (GRCm39) |
Q149K |
probably benign |
Het |
| Pkhd1l1 |
T |
A |
15: 44,392,955 (GRCm39) |
N1763K |
probably benign |
Het |
| Pla2g4a |
G |
A |
1: 149,748,338 (GRCm39) |
T282I |
probably damaging |
Het |
| Prpf39 |
A |
C |
12: 65,089,528 (GRCm39) |
N89H |
probably damaging |
Het |
| Rad54l2 |
A |
G |
9: 106,587,537 (GRCm39) |
F743L |
probably damaging |
Het |
| Raver2 |
A |
G |
4: 100,991,320 (GRCm39) |
|
probably null |
Het |
| Ric8b |
T |
C |
10: 84,783,709 (GRCm39) |
L189P |
probably damaging |
Het |
| Sccpdh |
T |
C |
1: 179,495,957 (GRCm39) |
F13L |
probably benign |
Het |
| Scd2 |
T |
C |
19: 44,291,448 (GRCm39) |
F296L |
probably damaging |
Het |
| Scg2 |
G |
T |
1: 79,414,023 (GRCm39) |
D233E |
probably benign |
Het |
| Sema5b |
C |
A |
16: 35,448,377 (GRCm39) |
|
probably null |
Het |
| Skint5 |
A |
T |
4: 113,636,286 (GRCm39) |
V644E |
unknown |
Het |
| Slc44a5 |
G |
T |
3: 153,969,678 (GRCm39) |
V612F |
possibly damaging |
Het |
| Snd1 |
C |
T |
6: 28,520,234 (GRCm39) |
R107* |
probably null |
Het |
| Sun5 |
G |
T |
2: 153,702,589 (GRCm39) |
T189K |
probably damaging |
Het |
| Tap1 |
A |
T |
17: 34,412,151 (GRCm39) |
E452V |
probably damaging |
Het |
| Tcam1 |
A |
G |
11: 106,173,652 (GRCm39) |
N32S |
probably benign |
Het |
| Tep1 |
T |
C |
14: 51,067,715 (GRCm39) |
E2167G |
probably damaging |
Het |
| Tm9sf1 |
C |
T |
14: 55,873,827 (GRCm39) |
R557H |
probably damaging |
Het |
| Tmem175 |
T |
C |
5: 108,793,821 (GRCm39) |
V317A |
probably damaging |
Het |
| Tsga13 |
A |
G |
6: 30,874,139 (GRCm39) |
V231A |
probably benign |
Het |
| Tspan12 |
A |
G |
6: 21,799,970 (GRCm39) |
S126P |
probably damaging |
Het |
| Uvrag |
G |
T |
7: 98,637,398 (GRCm39) |
D143E |
probably damaging |
Het |
| Vmn1r230 |
T |
A |
17: 21,067,036 (GRCm39) |
M75K |
possibly damaging |
Het |
| Vmn2r120 |
A |
T |
17: 57,852,287 (GRCm39) |
F10I |
probably benign |
Het |
| Vmn2r57 |
T |
C |
7: 41,049,284 (GRCm39) |
T822A |
probably benign |
Het |
| Vmn2r67 |
T |
C |
7: 84,799,768 (GRCm39) |
Y490C |
probably damaging |
Het |
| Zc3h7b |
T |
A |
15: 81,667,386 (GRCm39) |
W644R |
probably damaging |
Het |
| Zeb1 |
A |
G |
18: 5,766,962 (GRCm39) |
D491G |
probably damaging |
Het |
| Zfp709 |
TCGACG |
TCG |
8: 72,644,552 (GRCm39) |
|
probably benign |
Het |
| Zfp831 |
A |
T |
2: 174,486,308 (GRCm39) |
T328S |
possibly damaging |
Het |
|
| Other mutations in Myom2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Myom2
|
APN |
8 |
15,119,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00426:Myom2
|
APN |
8 |
15,119,502 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Myom2
|
APN |
8 |
15,164,289 (GRCm39) |
splice site |
probably null |
|
|
IGL01515:Myom2
|
APN |
8 |
15,172,655 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01649:Myom2
|
APN |
8 |
15,163,755 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01658:Myom2
|
APN |
8 |
15,127,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Myom2
|
APN |
8 |
15,156,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01924:Myom2
|
APN |
8 |
15,119,685 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01929:Myom2
|
APN |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02016:Myom2
|
APN |
8 |
15,175,195 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02511:Myom2
|
APN |
8 |
15,115,743 (GRCm39) |
missense |
probably benign |
|
|
IGL02558:Myom2
|
APN |
8 |
15,164,237 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02944:Myom2
|
APN |
8 |
15,154,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03052:Myom2
|
APN |
8 |
15,173,442 (GRCm39) |
splice site |
probably benign |
|
|
IGL03195:Myom2
|
APN |
8 |
15,161,844 (GRCm39) |
nonsense |
probably null |
|
|
IGL03288:Myom2
|
APN |
8 |
15,172,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03402:Myom2
|
APN |
8 |
15,115,731 (GRCm39) |
missense |
probably benign |
|
|
yomama
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
yoyoma
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0069:Myom2
|
UTSW |
8 |
15,167,624 (GRCm39) |
missense |
probably benign |
|
|
R0116:Myom2
|
UTSW |
8 |
15,167,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:Myom2
|
UTSW |
8 |
15,133,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0373:Myom2
|
UTSW |
8 |
15,148,419 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0463:Myom2
|
UTSW |
8 |
15,154,123 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0544:Myom2
|
UTSW |
8 |
15,119,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0629:Myom2
|
UTSW |
8 |
15,119,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0634:Myom2
|
UTSW |
8 |
15,169,216 (GRCm39) |
splice site |
probably benign |
|
|
R0645:Myom2
|
UTSW |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0730:Myom2
|
UTSW |
8 |
15,149,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0744:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R0836:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R1033:Myom2
|
UTSW |
8 |
15,158,934 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1103:Myom2
|
UTSW |
8 |
15,160,827 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1110:Myom2
|
UTSW |
8 |
15,172,413 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1353:Myom2
|
UTSW |
8 |
15,156,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:Myom2
|
UTSW |
8 |
15,172,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Myom2
|
UTSW |
8 |
15,154,059 (GRCm39) |
splice site |
probably benign |
|
|
R1576:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Myom2
|
UTSW |
8 |
15,115,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1884:Myom2
|
UTSW |
8 |
15,164,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1908:Myom2
|
UTSW |
8 |
15,131,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Myom2
|
UTSW |
8 |
15,182,599 (GRCm39) |
splice site |
probably null |
|
|
R1977:Myom2
|
UTSW |
8 |
15,135,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2018:Myom2
|
UTSW |
8 |
15,181,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Myom2
|
UTSW |
8 |
15,156,379 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2155:Myom2
|
UTSW |
8 |
15,134,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2314:Myom2
|
UTSW |
8 |
15,113,927 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2350:Myom2
|
UTSW |
8 |
15,158,835 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2358:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R2904:Myom2
|
UTSW |
8 |
15,148,348 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3418:Myom2
|
UTSW |
8 |
15,135,294 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3606:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3607:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Myom2
|
UTSW |
8 |
15,119,676 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3756:Myom2
|
UTSW |
8 |
15,152,650 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3902:Myom2
|
UTSW |
8 |
15,154,165 (GRCm39) |
missense |
probably benign |
|
|
R3951:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4240:Myom2
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4361:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4581:Myom2
|
UTSW |
8 |
15,156,459 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4736:Myom2
|
UTSW |
8 |
15,131,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5010:Myom2
|
UTSW |
8 |
15,133,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5108:Myom2
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5370:Myom2
|
UTSW |
8 |
15,149,343 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5427:Myom2
|
UTSW |
8 |
15,163,764 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5498:Myom2
|
UTSW |
8 |
15,179,142 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5504:Myom2
|
UTSW |
8 |
15,178,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Myom2
|
UTSW |
8 |
15,152,546 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5743:Myom2
|
UTSW |
8 |
15,130,914 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5745:Myom2
|
UTSW |
8 |
15,172,705 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5844:Myom2
|
UTSW |
8 |
15,181,182 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5854:Myom2
|
UTSW |
8 |
15,158,478 (GRCm39) |
missense |
probably benign |
|
|
R6141:Myom2
|
UTSW |
8 |
15,113,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Myom2
|
UTSW |
8 |
15,154,173 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6378:Myom2
|
UTSW |
8 |
15,149,356 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6829:Myom2
|
UTSW |
8 |
15,172,643 (GRCm39) |
nonsense |
probably null |
|
|
R6913:Myom2
|
UTSW |
8 |
15,115,710 (GRCm39) |
missense |
probably benign |
|
|
R6957:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6958:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6960:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6961:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6962:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6999:Myom2
|
UTSW |
8 |
15,134,531 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7148:Myom2
|
UTSW |
8 |
15,134,577 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7210:Myom2
|
UTSW |
8 |
15,154,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7298:Myom2
|
UTSW |
8 |
15,148,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7463:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably null |
0.94 |
|
R7535:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7573:Myom2
|
UTSW |
8 |
15,172,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7690:Myom2
|
UTSW |
8 |
15,161,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7794:Myom2
|
UTSW |
8 |
15,133,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7822:Myom2
|
UTSW |
8 |
15,158,454 (GRCm39) |
missense |
probably benign |
|
|
R7948:Myom2
|
UTSW |
8 |
15,135,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8094:Myom2
|
UTSW |
8 |
15,119,418 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8268:Myom2
|
UTSW |
8 |
15,179,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Myom2
|
UTSW |
8 |
15,182,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8514:Myom2
|
UTSW |
8 |
15,175,153 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8539:Myom2
|
UTSW |
8 |
15,164,254 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8790:Myom2
|
UTSW |
8 |
15,169,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8824:Myom2
|
UTSW |
8 |
15,164,169 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8895:Myom2
|
UTSW |
8 |
15,152,589 (GRCm39) |
nonsense |
probably null |
|
|
R9024:Myom2
|
UTSW |
8 |
15,113,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Myom2
|
UTSW |
8 |
15,154,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9224:Myom2
|
UTSW |
8 |
15,178,804 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9237:Myom2
|
UTSW |
8 |
15,152,591 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9321:Myom2
|
UTSW |
8 |
15,172,464 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9341:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9343:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9375:Myom2
|
UTSW |
8 |
15,149,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9455:Myom2
|
UTSW |
8 |
15,156,293 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9563:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
R9565:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
RF001:Myom2
|
UTSW |
8 |
15,131,418 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCAGAACAGACCTGGACTCCG -3'
(R):5'- CATGCAAACACTGAGCACTG -3'
Sequencing Primer
(F):5'- GAGTGCTAAGTGTCCCCATACAG -3'
(R):5'- GCACTGACAGGACCTGCATTTC -3'
|
| Posted On |
2018-02-28 |
Incidental Mutation