Mutagenetix > Incidental Mutation

Incidental Mutation 'R6277:Dnah12'

507741

Institutional Source

Beutler Lab

Gene Symbol

Dnah12

Ensembl Gene

ENSMUSG00000021879

Gene Name

dynein, axonemal, heavy chain 12

Synonyms

HL19, DHC3, Dnahc7l, 4921531P07Rik, HL-19, LOC380889, Hdhc3, Dnahc12, DLP12

MMRRC Submission

044447-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.196) question?

Stock #

R6277 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

26414429-26613660 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 26492439 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Leucine at position 1193 (H1193L)

Ref Sequence

ENSEMBL: ENSMUSP00000022433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022433] [ENSMUST00000073309]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000022433
AA Change: H1193L

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000022433
Gene: ENSMUSG00000021879
AA Change: H1193L

Domain	Start	End	E-Value	Type
low complexity region	127	140	N/A	INTRINSIC
coiled coil region	588	666	N/A	INTRINSIC
Pfam:DHC_N2	676	1113	1.1e-147	PFAM
AAA	1268	1407	1.15e0	SMART
Pfam:AAA_5	1552	1695	1.5e-7	PFAM
Blast:AAA	1709	1827	2e-24	BLAST
Blast:AAA	1848	1898	1e-16	BLAST
AAA	1903	2051	5.42e-4	SMART
Pfam:AAA_8	2238	2316	2e-18	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000073309

SMART Domains

Protein: ENSMUSP00000073035
Gene: ENSMUSG00000021879

Domain	Start	End	E-Value	Type
Pfam:AAA_6	1	203	4e-84	PFAM

Meta Mutation Damage Score

0.4420

Coding Region Coverage

1x: 99.9%
3x: 99.6%
10x: 98.2%
20x: 95.2%

Validation Efficiency

96% (70/73)

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
3425401B19Rik	A	G	14: 32,385,651 (GRCm39)	Y105H	possibly damaging	Het
4921539E11Rik	A	T	4: 103,088,668 (GRCm39)	Y179*	probably null	Het
Abca7	G	C	10: 79,841,992 (GRCm39)	V1042L	probably benign	Het
Adck5	C	A	15: 76,477,463 (GRCm39)	T99K	possibly damaging	Het
Adcy5	A	G	16: 35,109,896 (GRCm39)	T823A	probably benign	Het
Adra1d	G	T	2: 131,403,083 (GRCm39)	R336S	probably damaging	Het
Arhgap39	A	T	15: 76,619,337 (GRCm39)	M749K	probably damaging	Het
Arid4a	A	G	12: 71,086,665 (GRCm39)	R168G	possibly damaging	Het
Atxn10	A	G	15: 85,275,893 (GRCm39)	T317A	probably benign	Het
Bicc1	T	C	10: 70,863,731 (GRCm39)	K22E	possibly damaging	Het
Cacna1b	T	G	2: 24,620,808 (GRCm39)	T281P	probably damaging	Het
Ccdc174	A	T	6: 91,857,272 (GRCm39)	Q26L	probably damaging	Het
Celf3	T	C	3: 94,392,672 (GRCm39)	C124R	probably damaging	Het
Cfap44	A	G	16: 44,257,669 (GRCm39)	E1068G	probably benign	Het
Crybg1	T	A	10: 43,873,255 (GRCm39)	E1284D	probably benign	Het
Dcbld2	T	A	16: 58,272,119 (GRCm39)	Y392N	probably damaging	Het
Dcbld2	C	T	16: 58,285,866 (GRCm39)	P675L	probably damaging	Het
Efcab3	G	C	11: 104,901,148 (GRCm39)	E4422D	possibly damaging	Het
Ern2	A	G	7: 121,785,330 (GRCm39)	F16L	probably benign	Het
Fam163b	G	T	2: 27,002,763 (GRCm39)	T78N	probably benign	Het
Fbxw21	A	T	9: 108,974,623 (GRCm39)	I299K	possibly damaging	Het
Foxg1	A	G	12: 49,432,299 (GRCm39)	N344S	probably benign	Het
Git2	A	G	5: 114,871,308 (GRCm39)	I202T	probably damaging	Het
Gm11595	G	T	11: 99,663,510 (GRCm39)	P57T	unknown	Het
Gm12258	G	A	11: 58,745,113 (GRCm39)	V15M	probably damaging	Het
Gm15056	C	T	8: 21,390,914 (GRCm39)	G40S	probably damaging	Het
Gnal	C	A	18: 67,346,143 (GRCm39)	H274Q	probably damaging	Het
Hormad2	A	T	11: 4,371,583 (GRCm39)		probably null	Het
Ighv7-2	A	G	12: 113,876,087 (GRCm39)	I6T	probably benign	Het
Irf9	A	G	14: 55,845,109 (GRCm39)	D323G	probably benign	Het
Klhl23	G	T	2: 69,664,096 (GRCm39)	D482Y	probably damaging	Het
Lama4	A	G	10: 38,982,006 (GRCm39)	N1745S	probably damaging	Het
Lct	T	A	1: 128,231,974 (GRCm39)	Y625F	probably benign	Het
Lrrc26	T	C	2: 25,180,116 (GRCm39)	V39A	probably benign	Het
Mllt6	G	A	11: 97,564,774 (GRCm39)	A527T	probably damaging	Het
Mrgprb4	T	A	7: 47,848,649 (GRCm39)	D93V	probably benign	Het
Nlrp5	A	G	7: 23,120,880 (GRCm39)	D698G	probably damaging	Het
Or13p10	T	A	4: 118,523,520 (GRCm39)	S269T	probably benign	Het
Pacsin1	T	A	17: 27,924,969 (GRCm39)		probably null	Het
Padi3	A	T	4: 140,518,472 (GRCm39)		probably null	Het
Pcdha8	T	C	18: 37,127,411 (GRCm39)	I631T	probably damaging	Het
Pkn3	G	A	2: 29,972,957 (GRCm39)	G315D	possibly damaging	Het
Ppfibp1	T	A	6: 146,907,422 (GRCm39)	D228E	probably benign	Het
Prag1	G	T	8: 36,613,745 (GRCm39)	R1099L	probably damaging	Het
Pramel31	A	G	4: 144,090,223 (GRCm39)	E421G	probably damaging	Het
Prr36	A	G	8: 4,264,746 (GRCm39)		probably benign	Het
Prrc2c	A	G	1: 162,541,883 (GRCm39)	S369P	probably benign	Het
Ptprn2	A	G	12: 116,839,800 (GRCm39)	D441G	probably benign	Het
Slc9c1	G	A	16: 45,427,204 (GRCm39)		probably benign	Het
Slit1	G	A	19: 41,588,948 (GRCm39)	T1513I	possibly damaging	Het
Smcr8	C	T	11: 60,669,635 (GRCm39)	T261M	probably benign	Het
Spata17	G	A	1: 186,926,151 (GRCm39)	R60*	probably null	Het
Speer4f1	A	G	5: 17,681,241 (GRCm39)	R40G	probably damaging	Het
Spns3	A	G	11: 72,420,466 (GRCm39)	V340A	possibly damaging	Het
Srgap3	T	C	6: 112,716,344 (GRCm39)	I595V	probably benign	Het
Srms	G	A	2: 180,848,038 (GRCm39)	A489V	possibly damaging	Het
St3gal4	T	C	9: 34,964,558 (GRCm39)	N169S	probably damaging	Het
Taar5	T	A	10: 23,847,169 (GRCm39)	V189E	probably damaging	Het
Tbc1d32	G	A	10: 56,071,525 (GRCm39)	P333L	probably benign	Het
Tet3	G	T	6: 83,345,066 (GRCm39)	Y1790*	probably null	Het
Ticrr	T	A	7: 79,344,444 (GRCm39)	H1436Q	probably benign	Het
Top6bl	G	T	19: 4,677,250 (GRCm39)	S466*	probably null	Het
Ubl7	C	T	9: 57,830,555 (GRCm39)	L334F	possibly damaging	Het
Unc13a	A	G	8: 72,119,283 (GRCm39)		probably null	Het
Unc13c	T	C	9: 73,606,451 (GRCm39)	D1303G	probably damaging	Het
Vmn2r114	A	G	17: 23,509,954 (GRCm39)	L842P	possibly damaging	Het
Vps35	G	T	8: 85,987,857 (GRCm39)	Q765K	possibly damaging	Het
Zfp87	G	T	13: 74,520,643 (GRCm39)	S145*	probably null	Het
Zgrf1	C	T	3: 127,392,461 (GRCm39)	A1327V	possibly damaging	Het
Zkscan6	T	A	11: 65,718,983 (GRCm39)	S334R	probably benign	Het

Other mutations in Dnah12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01412:Dnah12	APN	14	26,492,962 (GRCm39)	missense	probably damaging	1.00
IGL01602:Dnah12	APN	14	26,431,430 (GRCm39)	splice site	probably benign
IGL01681:Dnah12	APN	14	26,443,315 (GRCm39)	missense	probably benign
IGL02082:Dnah12	APN	14	26,428,317 (GRCm39)	missense	possibly damaging	0.79
IGL02140:Dnah12	APN	14	26,437,732 (GRCm39)	missense	probably benign	0.20
IGL02170:Dnah12	APN	14	26,495,069 (GRCm39)	missense	probably damaging	0.99
IGL02174:Dnah12	APN	14	26,428,072 (GRCm39)	missense	probably benign	0.00
IGL02367:Dnah12	APN	14	26,430,316 (GRCm39)	missense	probably benign	0.30
IGL02418:Dnah12	APN	14	26,495,679 (GRCm39)	missense	probably damaging	1.00
IGL03039:Dnah12	APN	14	26,445,667 (GRCm39)	missense	probably benign	0.02
IGL03066:Dnah12	APN	14	26,418,553 (GRCm39)	missense	probably benign	0.06
drippings	UTSW	14	26,576,761 (GRCm39)	missense	probably damaging	1.00
grueben	UTSW	14	26,600,036 (GRCm39)	missense	probably damaging	1.00
BB010:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
BB020:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
F5770:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
FR4304:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4340:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4342:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
FR4589:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
IGL03055:Dnah12	UTSW	14	26,594,697 (GRCm39)	missense	probably damaging	1.00
LCD18:Dnah12	UTSW	14	26,571,342 (GRCm39)	missense	probably damaging	1.00
R0003:Dnah12	UTSW	14	26,494,601 (GRCm39)	missense	probably damaging	1.00
R0110:Dnah12	UTSW	14	26,520,856 (GRCm39)	missense	probably damaging	1.00
R0302:Dnah12	UTSW	14	26,521,956 (GRCm39)	missense	probably damaging	1.00
R0355:Dnah12	UTSW	14	26,427,272 (GRCm39)	splice site	probably null
R0364:Dnah12	UTSW	14	26,445,628 (GRCm39)	missense	probably benign	0.10
R0469:Dnah12	UTSW	14	26,520,856 (GRCm39)	missense	probably damaging	1.00
R0558:Dnah12	UTSW	14	26,430,465 (GRCm39)	missense	probably benign	0.00
R0709:Dnah12	UTSW	14	26,606,222 (GRCm39)	splice site	probably benign
R0734:Dnah12	UTSW	14	26,521,970 (GRCm39)	missense	probably benign	0.00
R1273:Dnah12	UTSW	14	26,460,375 (GRCm39)	nonsense	probably null
R1496:Dnah12	UTSW	14	26,431,403 (GRCm39)	missense	probably benign
R1503:Dnah12	UTSW	14	26,495,649 (GRCm39)	missense	probably damaging	1.00
R1535:Dnah12	UTSW	14	26,538,279 (GRCm39)	missense	possibly damaging	0.91
R1608:Dnah12	UTSW	14	26,488,147 (GRCm39)	missense	probably damaging	1.00
R1682:Dnah12	UTSW	14	26,500,840 (GRCm39)	missense	possibly damaging	0.71
R1758:Dnah12	UTSW	14	26,488,071 (GRCm39)	missense	probably benign	0.02
R1826:Dnah12	UTSW	14	26,432,174 (GRCm39)	missense	probably benign	0.01
R1829:Dnah12	UTSW	14	26,522,032 (GRCm39)	missense	probably damaging	1.00
R1829:Dnah12	UTSW	14	26,494,980 (GRCm39)	missense	probably damaging	1.00
R1862:Dnah12	UTSW	14	26,430,412 (GRCm39)	missense	probably benign	0.30
R1862:Dnah12	UTSW	14	26,418,553 (GRCm39)	missense	probably benign	0.06
R1913:Dnah12	UTSW	14	26,514,221 (GRCm39)	splice site	probably null
R1933:Dnah12	UTSW	14	26,455,650 (GRCm39)	missense	probably damaging	0.98
R2006:Dnah12	UTSW	14	26,536,416 (GRCm39)	missense	possibly damaging	0.95
R2045:Dnah12	UTSW	14	26,503,485 (GRCm39)	missense	probably null	1.00
R2113:Dnah12	UTSW	14	26,488,098 (GRCm39)	missense	probably damaging	1.00
R2125:Dnah12	UTSW	14	26,445,613 (GRCm39)	nonsense	probably null
R2126:Dnah12	UTSW	14	26,445,613 (GRCm39)	nonsense	probably null
R2207:Dnah12	UTSW	14	26,503,744 (GRCm39)	missense	probably damaging	0.99
R2213:Dnah12	UTSW	14	26,460,485 (GRCm39)	missense	probably benign	0.06
R2511:Dnah12	UTSW	14	26,491,907 (GRCm39)	missense	possibly damaging	0.65
R2875:Dnah12	UTSW	14	26,598,907 (GRCm39)	missense	probably benign	0.05
R2875:Dnah12	UTSW	14	26,414,625 (GRCm39)	missense	probably benign	0.04
R3551:Dnah12	UTSW	14	26,492,929 (GRCm39)	missense	probably benign	0.01
R3713:Dnah12	UTSW	14	26,534,747 (GRCm39)	missense	probably benign
R3729:Dnah12	UTSW	14	26,427,220 (GRCm39)	missense	probably benign	0.02
R3799:Dnah12	UTSW	14	26,492,880 (GRCm39)	missense	probably damaging	1.00
R3846:Dnah12	UTSW	14	26,431,366 (GRCm39)	missense	probably benign	0.00
R3892:Dnah12	UTSW	14	26,578,573 (GRCm39)	missense	probably benign	0.03
R3921:Dnah12	UTSW	14	26,493,008 (GRCm39)	missense	probably damaging	1.00
R3940:Dnah12	UTSW	14	26,444,754 (GRCm39)	missense	probably benign
R4065:Dnah12	UTSW	14	26,492,405 (GRCm39)	missense	probably benign	0.02
R4113:Dnah12	UTSW	14	26,414,722 (GRCm39)	missense	probably damaging	0.98
R4249:Dnah12	UTSW	14	26,430,341 (GRCm39)	missense	possibly damaging	0.70
R4259:Dnah12	UTSW	14	26,520,883 (GRCm39)	missense	probably benign	0.01
R4260:Dnah12	UTSW	14	26,520,883 (GRCm39)	missense	probably benign	0.01
R4348:Dnah12	UTSW	14	26,536,498 (GRCm39)	missense	possibly damaging	0.94
R4457:Dnah12	UTSW	14	26,537,464 (GRCm39)	missense	probably damaging	1.00
R4490:Dnah12	UTSW	14	26,455,758 (GRCm39)	missense	possibly damaging	0.67
R4491:Dnah12	UTSW	14	26,455,758 (GRCm39)	missense	possibly damaging	0.67
R4494:Dnah12	UTSW	14	26,593,812 (GRCm39)	missense	probably damaging	0.99
R4523:Dnah12	UTSW	14	26,598,915 (GRCm39)	missense	possibly damaging	0.83
R4523:Dnah12	UTSW	14	26,491,979 (GRCm39)	missense	probably damaging	0.97
R4546:Dnah12	UTSW	14	26,494,971 (GRCm39)	missense	probably damaging	1.00
R4584:Dnah12	UTSW	14	26,494,551 (GRCm39)	missense	probably damaging	1.00
R4624:Dnah12	UTSW	14	26,456,913 (GRCm39)	missense	possibly damaging	0.82
R4689:Dnah12	UTSW	14	26,427,994 (GRCm39)	missense	probably benign	0.00
R4727:Dnah12	UTSW	14	26,594,274 (GRCm39)	missense	probably damaging	1.00
R4732:Dnah12	UTSW	14	26,503,741 (GRCm39)	missense	probably damaging	1.00
R4733:Dnah12	UTSW	14	26,503,741 (GRCm39)	missense	probably damaging	1.00
R4851:Dnah12	UTSW	14	26,437,784 (GRCm39)	nonsense	probably null
R4879:Dnah12	UTSW	14	26,439,201 (GRCm39)	critical splice donor site	probably null
R4893:Dnah12	UTSW	14	26,431,325 (GRCm39)	missense	possibly damaging	0.66
R4915:Dnah12	UTSW	14	26,455,725 (GRCm39)	missense	probably damaging	1.00
R4927:Dnah12	UTSW	14	26,583,762 (GRCm39)	nonsense	probably null
R4939:Dnah12	UTSW	14	26,613,481 (GRCm39)	missense	probably damaging	1.00
R4962:Dnah12	UTSW	14	26,437,855 (GRCm39)	missense	probably benign	0.00
R5011:Dnah12	UTSW	14	26,431,326 (GRCm39)	missense	probably benign	0.03
R5013:Dnah12	UTSW	14	26,431,326 (GRCm39)	missense	probably benign	0.03
R5043:Dnah12	UTSW	14	26,606,147 (GRCm39)	missense	probably damaging	1.00
R5049:Dnah12	UTSW	14	26,456,852 (GRCm39)	missense	probably benign	0.09
R5122:Dnah12	UTSW	14	26,439,155 (GRCm39)	missense	probably benign	0.00
R5135:Dnah12	UTSW	14	26,492,434 (GRCm39)	missense	probably damaging	0.99
R5149:Dnah12	UTSW	14	26,572,883 (GRCm39)	nonsense	probably null
R5154:Dnah12	UTSW	14	26,571,320 (GRCm39)	missense	probably benign	0.12
R5206:Dnah12	UTSW	14	26,491,942 (GRCm39)	missense	probably damaging	1.00
R5307:Dnah12	UTSW	14	26,414,641 (GRCm39)	missense	possibly damaging	0.49
R5330:Dnah12	UTSW	14	26,495,787 (GRCm39)	missense	probably damaging	1.00
R5335:Dnah12	UTSW	14	26,601,695 (GRCm39)	missense	probably damaging	1.00
R5339:Dnah12	UTSW	14	26,536,494 (GRCm39)	missense	possibly damaging	0.83
R5354:Dnah12	UTSW	14	26,496,299 (GRCm39)	splice site	probably null
R5389:Dnah12	UTSW	14	26,456,904 (GRCm39)	missense	probably damaging	1.00
R5434:Dnah12	UTSW	14	26,581,256 (GRCm39)	missense	probably damaging	1.00
R5466:Dnah12	UTSW	14	26,493,007 (GRCm39)	missense	probably damaging	1.00
R5655:Dnah12	UTSW	14	26,431,424 (GRCm39)	missense	probably benign	0.01
R5681:Dnah12	UTSW	14	26,537,452 (GRCm39)	missense	probably benign	0.32
R5824:Dnah12	UTSW	14	26,492,475 (GRCm39)	critical splice donor site	probably null
R5863:Dnah12	UTSW	14	26,576,878 (GRCm39)	missense	probably damaging	1.00
R5890:Dnah12	UTSW	14	26,428,039 (GRCm39)	missense	probably benign	0.09
R5912:Dnah12	UTSW	14	26,491,965 (GRCm39)	nonsense	probably null
R5916:Dnah12	UTSW	14	26,428,073 (GRCm39)	missense	possibly damaging	0.92
R5941:Dnah12	UTSW	14	26,428,022 (GRCm39)	missense	probably benign	0.00
R5987:Dnah12	UTSW	14	26,608,828 (GRCm39)	missense	possibly damaging	0.54
R5992:Dnah12	UTSW	14	26,418,496 (GRCm39)	missense	probably benign	0.04
R6132:Dnah12	UTSW	14	26,439,066 (GRCm39)	missense	probably damaging	1.00
R6136:Dnah12	UTSW	14	26,597,227 (GRCm39)	missense	probably damaging	0.99
R6158:Dnah12	UTSW	14	26,495,642 (GRCm39)	missense	possibly damaging	0.95
R6183:Dnah12	UTSW	14	26,583,726 (GRCm39)	missense	probably damaging	1.00
R6191:Dnah12	UTSW	14	26,431,412 (GRCm39)	missense	probably benign	0.03
R6235:Dnah12	UTSW	14	26,576,761 (GRCm39)	missense	probably damaging	1.00
R6332:Dnah12	UTSW	14	26,439,129 (GRCm39)	missense	probably damaging	0.99
R6334:Dnah12	UTSW	14	26,427,989 (GRCm39)	missense	possibly damaging	0.51
R6443:Dnah12	UTSW	14	26,600,008 (GRCm39)	missense	probably benign	0.06
R6480:Dnah12	UTSW	14	26,594,412 (GRCm39)	missense	probably damaging	1.00
R6530:Dnah12	UTSW	14	26,456,865 (GRCm39)	missense	probably damaging	1.00
R6678:Dnah12	UTSW	14	26,456,847 (GRCm39)	missense	probably damaging	1.00
R6709:Dnah12	UTSW	14	26,594,706 (GRCm39)	missense	probably damaging	1.00
R6724:Dnah12	UTSW	14	26,518,180 (GRCm39)	missense	probably benign	0.02
R6745:Dnah12	UTSW	14	26,428,383 (GRCm39)	missense	probably damaging	0.99
R6788:Dnah12	UTSW	14	26,523,470 (GRCm39)	missense	probably damaging	0.99
R6894:Dnah12	UTSW	14	26,456,904 (GRCm39)	missense	probably damaging	1.00
R6912:Dnah12	UTSW	14	26,600,036 (GRCm39)	missense	probably damaging	1.00
R6982:Dnah12	UTSW	14	26,521,033 (GRCm39)	splice site	probably null
R7001:Dnah12	UTSW	14	26,601,681 (GRCm39)	missense	probably damaging	0.99
R7002:Dnah12	UTSW	14	26,598,955 (GRCm39)	missense	probably damaging	1.00
R7017:Dnah12	UTSW	14	26,456,835 (GRCm39)	missense	probably benign
R7107:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7108:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7121:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7122:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,523,370 (GRCm39)	missense	probably damaging	0.99
R7150:Dnah12	UTSW	14	26,583,689 (GRCm39)	missense	probably damaging	0.99
R7188:Dnah12	UTSW	14	26,536,370 (GRCm39)	missense	probably benign	0.04
R7201:Dnah12	UTSW	14	26,536,579 (GRCm39)	missense	probably benign	0.08
R7202:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7204:Dnah12	UTSW	14	26,503,442 (GRCm39)	missense	probably damaging	0.99
R7204:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7205:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7206:Dnah12	UTSW	14	26,500,869 (GRCm39)	critical splice donor site	probably null
R7219:Dnah12	UTSW	14	26,576,837 (GRCm39)	missense	probably damaging	0.99
R7337:Dnah12	UTSW	14	26,488,534 (GRCm39)	splice site	probably null
R7339:Dnah12	UTSW	14	26,594,277 (GRCm39)	missense	probably benign
R7363:Dnah12	UTSW	14	26,445,766 (GRCm39)	missense	probably benign
R7426:Dnah12	UTSW	14	26,445,781 (GRCm39)	missense	probably benign	0.01
R7472:Dnah12	UTSW	14	26,578,592 (GRCm39)	missense	probably benign	0.01
R7579:Dnah12	UTSW	14	26,492,460 (GRCm39)	missense	probably benign	0.05
R7655:Dnah12	UTSW	14	26,581,273 (GRCm39)	missense	probably benign	0.21
R7656:Dnah12	UTSW	14	26,581,273 (GRCm39)	missense	probably benign	0.21
R7694:Dnah12	UTSW	14	26,503,337 (GRCm39)	missense	probably damaging	1.00
R7730:Dnah12	UTSW	14	26,507,890 (GRCm39)	missense	probably damaging	1.00
R7837:Dnah12	UTSW	14	26,518,176 (GRCm39)	missense	probably benign	0.01
R7855:Dnah12	UTSW	14	26,551,286 (GRCm39)	missense	probably benign	0.14
R7870:Dnah12	UTSW	14	26,578,486 (GRCm39)	missense	probably benign	0.00
R7920:Dnah12	UTSW	14	26,578,499 (GRCm39)	missense	possibly damaging	0.58
R7933:Dnah12	UTSW	14	26,488,072 (GRCm39)	missense	probably benign	0.00
R7956:Dnah12	UTSW	14	26,430,427 (GRCm39)	missense	probably damaging	0.96
R8192:Dnah12	UTSW	14	26,428,036 (GRCm39)	missense	probably benign
R8263:Dnah12	UTSW	14	26,613,421 (GRCm39)	missense	noncoding transcript
R8287:Dnah12	UTSW	14	26,534,560 (GRCm39)	missense	probably benign
R8336:Dnah12	UTSW	14	26,432,220 (GRCm39)	missense	probably benign	0.01
R8362:Dnah12	UTSW	14	26,576,788 (GRCm39)	missense	probably damaging	1.00
R8392:Dnah12	UTSW	14	26,607,869 (GRCm39)	missense	probably benign
R8458:Dnah12	UTSW	14	26,548,849 (GRCm39)	critical splice acceptor site	probably null
R8481:Dnah12	UTSW	14	26,575,753 (GRCm39)	missense	probably benign	0.02
R8551:Dnah12	UTSW	14	26,496,227 (GRCm39)	missense	probably damaging	0.97
R8669:Dnah12	UTSW	14	26,552,582 (GRCm39)	splice site	probably benign
R8698:Dnah12	UTSW	14	26,428,418 (GRCm39)	missense	probably benign	0.02
R8709:Dnah12	UTSW	14	26,414,757 (GRCm39)	missense	probably benign	0.00
R8778:Dnah12	UTSW	14	26,455,718 (GRCm39)	missense	probably benign	0.29
R9049:Dnah12	UTSW	14	26,443,275 (GRCm39)	missense	probably benign	0.00
R9087:Dnah12	UTSW	14	26,546,503 (GRCm39)	missense	probably damaging	1.00
R9099:Dnah12	UTSW	14	26,492,325 (GRCm39)	missense	probably benign	0.31
R9153:Dnah12	UTSW	14	26,536,569 (GRCm39)	missense	probably damaging	1.00
R9177:Dnah12	UTSW	14	26,571,255 (GRCm39)	missense	possibly damaging	0.84
R9214:Dnah12	UTSW	14	26,445,060 (GRCm39)	missense	probably benign	0.02
R9268:Dnah12	UTSW	14	26,571,255 (GRCm39)	missense	possibly damaging	0.84
R9274:Dnah12	UTSW	14	26,537,374 (GRCm39)	missense	probably benign	0.00
R9293:Dnah12	UTSW	14	26,495,016 (GRCm39)	missense	probably benign
R9322:Dnah12	UTSW	14	26,492,934 (GRCm39)	missense	possibly damaging	0.75
R9353:Dnah12	UTSW	14	26,578,507 (GRCm39)	missense	probably damaging	1.00
R9506:Dnah12	UTSW	14	26,514,168 (GRCm39)	missense	probably benign	0.00
R9518:Dnah12	UTSW	14	26,495,713 (GRCm39)	missense	probably damaging	1.00
R9524:Dnah12	UTSW	14	26,572,494 (GRCm39)	missense	probably null	0.91
R9562:Dnah12	UTSW	14	26,597,281 (GRCm39)	missense	possibly damaging	0.58
R9565:Dnah12	UTSW	14	26,597,281 (GRCm39)	missense	possibly damaging	0.58
R9573:Dnah12	UTSW	14	26,414,619 (GRCm39)	missense	probably benign
R9581:Dnah12	UTSW	14	26,491,985 (GRCm39)	missense	probably damaging	1.00
R9689:Dnah12	UTSW	14	26,590,871 (GRCm39)	missense	probably null	1.00
R9727:Dnah12	UTSW	14	26,523,510 (GRCm39)	nonsense	probably null
V7580:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
V7581:Dnah12	UTSW	14	26,495,050 (GRCm39)	missense	possibly damaging	0.95
X0018:Dnah12	UTSW	14	26,536,437 (GRCm39)	missense	probably damaging	1.00
X0027:Dnah12	UTSW	14	26,538,245 (GRCm39)	missense	probably damaging	1.00
X0065:Dnah12	UTSW	14	26,536,602 (GRCm39)	missense	possibly damaging	0.93
Z1177:Dnah12	UTSW	14	26,597,172 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TGTGAGATATATGTTCTAGGCATAGTC -3'
(R):5'- TCTGTATCATGTGAGACACCTAGGAAG -3'

Sequencing Primer
(F):5'- ATGTTCTAGGCATAGTCATACGTG -3'
(R):5'- GGGTAGCCTAGTCTACATAGCTAC -3'

Posted On

2018-03-15