Mutagenetix > Incidental Mutation

Incidental Mutation 'R6283:Igsf10'

508035

Institutional Source

Beutler Lab

Gene Symbol

Igsf10

Ensembl Gene

ENSMUSG00000036334

Gene Name

immunoglobulin superfamily, member 10

Synonyms

6530405F15Rik, CMF608, Adlican2

MMRRC Submission

044453-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.193) question?

Stock #

R6283 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

59224156-59251815 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 59226870 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Serine at position 2268 (T2268S)

Ref Sequence

ENSEMBL: ENSMUSP00000141391 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039419] [ENSMUST00000040325] [ENSMUST00000164225] [ENSMUST00000193455] [ENSMUST00000194546] [ENSMUST00000199659]

AlphaFold

Q3V1M1

Predicted Effect

probably damaging
Transcript: ENSMUST00000039419
AA Change: T2268S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: T2268S

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000040325

SMART Domains

Protein: ENSMUSP00000042269
Gene: ENSMUSG00000056476

Domain	Start	End	E-Value	Type
Med12	101	161	1.71e-24	SMART
low complexity region	216	224	N/A	INTRINSIC
low complexity region	269	278	N/A	INTRINSIC
Pfam:Med12-LCEWAV	282	730	2.6e-207	PFAM
low complexity region	744	758	N/A	INTRINSIC
low complexity region	853	872	N/A	INTRINSIC
low complexity region	1455	1466	N/A	INTRINSIC
low complexity region	1728	1742	N/A	INTRINSIC
low complexity region	1769	1783	N/A	INTRINSIC
Pfam:Med12-PQL	1803	2029	2.3e-14	PFAM
low complexity region	2055	2076	N/A	INTRINSIC
low complexity region	2083	2101	N/A	INTRINSIC
low complexity region	2116	2136	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000164225

SMART Domains

Protein: ENSMUSP00000127038
Gene: ENSMUSG00000056476

Domain	Start	End	E-Value	Type
Med12	101	161	1.71e-24	SMART
low complexity region	216	224	N/A	INTRINSIC
low complexity region	269	278	N/A	INTRINSIC
Pfam:Med12-LCEWAV	283	765	5e-187	PFAM
low complexity region	779	793	N/A	INTRINSIC
low complexity region	888	907	N/A	INTRINSIC
low complexity region	1490	1501	N/A	INTRINSIC
low complexity region	1763	1777	N/A	INTRINSIC
low complexity region	1804	1818	N/A	INTRINSIC
Pfam:Med12-PQL	1840	2063	9.7e-66	PFAM
low complexity region	2090	2111	N/A	INTRINSIC
low complexity region	2118	2136	N/A	INTRINSIC
low complexity region	2151	2171	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000193455
AA Change: T2268S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: T2268S

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000194546
AA Change: T2268S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: T2268S

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
LRRNT	28	61	3.24e-4	SMART
LRR	57	79	9.24e1	SMART
LRR	80	103	2.02e-1	SMART
LRR	104	127	7.16e0	SMART
LRR_TYP	128	151	1.2e-3	SMART
LRR	152	175	1.25e-1	SMART
LRR	188	207	2.33e2	SMART
LRRCT	219	280	4.19e-4	SMART
IGc2	488	558	2.34e-4	SMART
IGc2	586	652	7.88e-11	SMART
low complexity region	917	930	N/A	INTRINSIC
low complexity region	1175	1185	N/A	INTRINSIC
low complexity region	1245	1263	N/A	INTRINSIC
low complexity region	1311	1321	N/A	INTRINSIC
low complexity region	1449	1465	N/A	INTRINSIC
IGc2	1632	1701	7.69e-14	SMART
IGc2	1729	1798	5.07e-14	SMART
IGc2	1826	1895	2.19e-9	SMART
IGc2	1925	1994	4.59e-12	SMART
IGc2	2022	2097	1.33e-8	SMART
IGc2	2125	2191	2.96e-15	SMART
IGc2	2223	2291	2.03e-4	SMART
IGc2	2321	2389	9.99e-13	SMART
IGc2	2416	2484	3.03e-12	SMART
IGc2	2512	2583	7.76e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000197374

Predicted Effect

probably benign
Transcript: ENSMUST00000199659

SMART Domains

Protein: ENSMUSP00000142903
Gene: ENSMUSG00000056476

Domain	Start	End	E-Value	Type
Med12	101	161	1.71e-24	SMART
low complexity region	216	224	N/A	INTRINSIC
low complexity region	269	278	N/A	INTRINSIC
Pfam:Med12-LCEWAV	282	765	5.5e-209	PFAM
low complexity region	779	793	N/A	INTRINSIC
low complexity region	888	907	N/A	INTRINSIC
low complexity region	1490	1501	N/A	INTRINSIC
low complexity region	1761	1775	N/A	INTRINSIC
low complexity region	1802	1816	N/A	INTRINSIC
Pfam:Med12-PQL	1836	2062	1.7e-15	PFAM
low complexity region	2088	2130	N/A	INTRINSIC
low complexity region	2144	2164	N/A	INTRINSIC

Meta Mutation Damage Score

0.2125

Coding Region Coverage

1x: 99.9%
3x: 99.6%
10x: 98.0%
20x: 94.1%

Validation Efficiency

100% (59/59)

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acsf3	C	A	8: 123,512,694 (GRCm39)	R372S	probably damaging	Het
Adamts20	A	G	15: 94,249,602 (GRCm39)	S472P	probably benign	Het
Bhlhe40	T	C	6: 108,641,992 (GRCm39)	L312P	probably damaging	Het
Ccdc180	A	G	4: 45,902,486 (GRCm39)	E305G	possibly damaging	Het
Ccdc83	T	A	7: 89,885,615 (GRCm39)	R257*	probably null	Het
Cd209e	G	A	8: 3,899,212 (GRCm39)	Q167*	probably null	Het
Cd300e	G	A	11: 114,945,380 (GRCm39)	T138I	probably benign	Het
Ces2c	A	T	8: 105,576,331 (GRCm39)	M115L	probably benign	Het
Cfap61	T	A	2: 145,971,022 (GRCm39)		probably null	Het
Chd1l	G	A	3: 97,494,483 (GRCm39)	A399V	probably damaging	Het
Cic	C	T	7: 24,985,459 (GRCm39)	S301L	probably damaging	Het
Cks2	A	G	13: 51,799,495 (GRCm39)	H16R	probably benign	Het
Copa	A	T	1: 171,946,415 (GRCm39)	H953L	possibly damaging	Het
Ctdsp2	T	C	10: 126,831,749 (GRCm39)	V145A	possibly damaging	Het
Cyp2j13	A	G	4: 95,945,074 (GRCm39)	V377A	possibly damaging	Het
Dhx57	A	G	17: 80,582,234 (GRCm39)	V404A	probably benign	Het
Dock2	T	C	11: 34,598,152 (GRCm39)	S340G	probably damaging	Het
Ggps1	A	G	13: 14,232,379 (GRCm39)		probably null	Het
Gm10549	C	A	18: 33,597,358 (GRCm39)		probably benign	Het
Gm11444	T	C	11: 85,737,617 (GRCm39)		probably null	Het
Grina	A	G	15: 76,132,751 (GRCm39)	T173A	possibly damaging	Het
Hcrtr1	G	A	4: 130,029,133 (GRCm39)	T223I	probably benign	Het
Inhca	G	A	9: 103,159,834 (GRCm39)	R14*	probably null	Het
Ino80d	C	T	1: 63,101,285 (GRCm39)	R447Q	probably damaging	Het
Inpp4b	C	T	8: 82,497,462 (GRCm39)	T94M	probably damaging	Het
Itga2	A	G	13: 115,005,786 (GRCm39)	Y465H	probably damaging	Het
Knl1	A	G	2: 118,900,767 (GRCm39)	T823A	probably damaging	Het
Krtap4-16	A	G	11: 99,741,861 (GRCm39)	S180P	unknown	Het
Ldc1	A	G	4: 130,115,534 (GRCm39)	S5P	probably benign	Het
Lpar6	A	T	14: 73,476,297 (GRCm39)	D86V	probably damaging	Het
Muc5ac	C	A	7: 141,370,601 (GRCm39)	C2500*	probably null	Het
Mzf1	T	C	7: 12,787,296 (GRCm39)		probably benign	Het
Or4f58	A	C	2: 111,851,605 (GRCm39)	M198R	possibly damaging	Het
Or5d46	T	A	2: 88,170,002 (GRCm39)	I31N	probably benign	Het
Or5m3	G	T	2: 85,838,443 (GRCm39)	V108L	possibly damaging	Het
Or7a36	T	C	10: 78,820,113 (GRCm39)	V163A	probably benign	Het
Otogl	T	G	10: 107,626,361 (GRCm39)	E1501A	probably damaging	Het
Pcdh10	T	A	3: 45,335,989 (GRCm39)	S768T	possibly damaging	Het
Pcnx2	G	T	8: 126,604,325 (GRCm39)	Q644K	probably damaging	Het
Pdzd9	T	A	7: 120,259,449 (GRCm39)	I180F	possibly damaging	Het
Pinx1	A	C	14: 64,115,621 (GRCm39)	N152T	probably benign	Het
Prr14l	T	C	5: 32,987,608 (GRCm39)	E629G	probably benign	Het
Qpctl	T	A	7: 18,882,345 (GRCm39)	I104F	probably benign	Het
Rabep1	C	T	11: 70,808,505 (GRCm39)	A444V	probably damaging	Het
Rnf150	A	G	8: 83,717,183 (GRCm39)	Y230C	probably damaging	Het
Slc25a27	A	C	17: 43,968,621 (GRCm39)	V152G	probably damaging	Het
Swt1	A	G	1: 151,260,084 (GRCm39)	S772P	possibly damaging	Het
Tenm4	A	G	7: 96,523,701 (GRCm39)	T1711A	probably benign	Het
Tfap2d	G	C	1: 19,174,702 (GRCm39)	G52R	probably benign	Het
Tmem265	T	G	7: 127,164,044 (GRCm39)	V86G	possibly damaging	Het
Trpm8	C	T	1: 88,276,054 (GRCm39)	H551Y	probably benign	Het
Ttc6	T	G	12: 57,749,048 (GRCm39)	Y1327D	possibly damaging	Het
Uevld	G	T	7: 46,587,729 (GRCm39)	Q324K	possibly damaging	Het
Vmn2r111	T	C	17: 22,778,032 (GRCm39)	N549S	possibly damaging	Het
Vmn2r73	C	T	7: 85,521,049 (GRCm39)	M306I	probably benign	Het
Vmn2r93	T	A	17: 18,524,366 (GRCm39)	M120K	probably benign	Het
Zfp804b	T	A	5: 6,819,908 (GRCm39)	I1016F	probably benign	Het
Zfp90	T	C	8: 107,152,026 (GRCm39)	C580R	probably damaging	Het

Other mutations in Igsf10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00773:Igsf10	APN	3	59,238,960 (GRCm39)	missense	probably benign	0.03
IGL00790:Igsf10	APN	3	59,226,938 (GRCm39)	missense	probably damaging	1.00
IGL00916:Igsf10	APN	3	59,238,548 (GRCm39)	missense	probably damaging	0.97
IGL00928:Igsf10	APN	3	59,238,018 (GRCm39)	missense	probably benign	0.00
IGL01066:Igsf10	APN	3	59,235,203 (GRCm39)	critical splice donor site	probably null
IGL01107:Igsf10	APN	3	59,238,945 (GRCm39)	missense	probably damaging	1.00
IGL01420:Igsf10	APN	3	59,227,071 (GRCm39)	missense	probably benign	0.02
IGL01533:Igsf10	APN	3	59,226,651 (GRCm39)	missense	probably damaging	0.98
IGL01537:Igsf10	APN	3	59,237,452 (GRCm39)	missense	probably benign	0.00
IGL01676:Igsf10	APN	3	59,236,756 (GRCm39)	missense	probably benign	0.17
IGL01676:Igsf10	APN	3	59,233,432 (GRCm39)	missense	probably benign	0.06
IGL01960:Igsf10	APN	3	59,226,158 (GRCm39)	missense	probably benign	0.00
IGL02123:Igsf10	APN	3	59,226,081 (GRCm39)	missense	probably damaging	0.97
IGL02198:Igsf10	APN	3	59,233,399 (GRCm39)	missense	possibly damaging	0.95
IGL02268:Igsf10	APN	3	59,238,573 (GRCm39)	nonsense	probably null
IGL02313:Igsf10	APN	3	59,238,111 (GRCm39)	missense	probably benign	0.01
IGL02368:Igsf10	APN	3	59,235,652 (GRCm39)	missense	probably benign
IGL02494:Igsf10	APN	3	59,235,427 (GRCm39)	missense	probably damaging	0.98
IGL02549:Igsf10	APN	3	59,236,662 (GRCm39)	missense	probably benign	0.03
IGL02616:Igsf10	APN	3	59,226,027 (GRCm39)	missense	probably benign	0.06
IGL02957:Igsf10	APN	3	59,238,285 (GRCm39)	missense	probably damaging	1.00
IGL03067:Igsf10	APN	3	59,226,339 (GRCm39)	missense	probably benign	0.25
IGL03104:Igsf10	APN	3	59,226,905 (GRCm39)	missense	probably damaging	1.00
IGL03124:Igsf10	APN	3	59,227,086 (GRCm39)	missense	probably benign	0.01
IGL03212:Igsf10	APN	3	59,235,586 (GRCm39)	missense	probably benign	0.09
IGL03347:Igsf10	APN	3	59,239,321 (GRCm39)	missense	possibly damaging	0.94
IGL03357:Igsf10	APN	3	59,243,632 (GRCm39)	missense	probably benign	0.35
F6893:Igsf10	UTSW	3	59,238,481 (GRCm39)	missense	probably damaging	1.00
FR4449:Igsf10	UTSW	3	59,226,531 (GRCm39)	missense	probably damaging	1.00
PIT1430001:Igsf10	UTSW	3	59,235,579 (GRCm39)	missense	probably benign	0.06
PIT4402001:Igsf10	UTSW	3	59,233,000 (GRCm39)	missense	probably benign	0.00
PIT4810001:Igsf10	UTSW	3	59,225,903 (GRCm39)	missense	probably damaging	1.00
R0068:Igsf10	UTSW	3	59,238,045 (GRCm39)	missense	probably damaging	0.98
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0095:Igsf10	UTSW	3	59,238,617 (GRCm39)	nonsense	probably null
R0112:Igsf10	UTSW	3	59,233,429 (GRCm39)	missense	probably benign	0.00
R0141:Igsf10	UTSW	3	59,238,253 (GRCm39)	missense	probably damaging	1.00
R0538:Igsf10	UTSW	3	59,227,527 (GRCm39)	missense	probably damaging	0.99
R0551:Igsf10	UTSW	3	59,236,089 (GRCm39)	missense	probably benign	0.01
R0556:Igsf10	UTSW	3	59,236,296 (GRCm39)	missense	probably benign	0.02
R0582:Igsf10	UTSW	3	59,227,188 (GRCm39)	missense	probably benign	0.00
R0630:Igsf10	UTSW	3	59,233,483 (GRCm39)	missense	probably damaging	1.00
R0675:Igsf10	UTSW	3	59,236,015 (GRCm39)	missense	probably benign	0.14
R0948:Igsf10	UTSW	3	59,238,525 (GRCm39)	missense	probably damaging	1.00
R1252:Igsf10	UTSW	3	59,239,269 (GRCm39)	missense	probably benign	0.03
R1412:Igsf10	UTSW	3	59,235,196 (GRCm39)	splice site	probably benign
R1473:Igsf10	UTSW	3	59,226,188 (GRCm39)	missense	probably damaging	1.00
R1585:Igsf10	UTSW	3	59,237,838 (GRCm39)	missense	probably damaging	1.00
R1650:Igsf10	UTSW	3	59,233,583 (GRCm39)	missense	probably damaging	1.00
R1660:Igsf10	UTSW	3	59,238,706 (GRCm39)	missense	probably damaging	1.00
R1671:Igsf10	UTSW	3	59,235,921 (GRCm39)	nonsense	probably null
R1748:Igsf10	UTSW	3	59,226,514 (GRCm39)	missense	probably damaging	1.00
R1758:Igsf10	UTSW	3	59,236,617 (GRCm39)	missense	probably benign	0.09
R1856:Igsf10	UTSW	3	59,238,693 (GRCm39)	missense	possibly damaging	0.63
R1912:Igsf10	UTSW	3	59,236,993 (GRCm39)	missense	probably benign	0.40
R2148:Igsf10	UTSW	3	59,243,998 (GRCm39)	missense	possibly damaging	0.77
R2155:Igsf10	UTSW	3	59,239,101 (GRCm39)	missense	probably damaging	1.00
R2509:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2511:Igsf10	UTSW	3	59,239,287 (GRCm39)	missense	probably damaging	1.00
R2680:Igsf10	UTSW	3	59,232,875 (GRCm39)	missense	probably benign	0.14
R2913:Igsf10	UTSW	3	59,239,157 (GRCm39)	missense	possibly damaging	0.70
R2927:Igsf10	UTSW	3	59,236,848 (GRCm39)	missense	probably benign
R3547:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3547:Igsf10	UTSW	3	59,237,962 (GRCm39)	missense	probably benign	0.02
R3548:Igsf10	UTSW	3	59,243,935 (GRCm39)	missense	probably damaging	1.00
R3620:Igsf10	UTSW	3	59,243,752 (GRCm39)	missense	probably damaging	1.00
R3732:Igsf10	UTSW	3	59,233,135 (GRCm39)	missense	probably benign	0.29
R3743:Igsf10	UTSW	3	59,233,546 (GRCm39)	missense	possibly damaging	0.69
R3973:Igsf10	UTSW	3	59,239,345 (GRCm39)	missense	probably damaging	1.00
R4005:Igsf10	UTSW	3	59,235,981 (GRCm39)	missense	probably benign	0.00
R4184:Igsf10	UTSW	3	59,227,152 (GRCm39)	missense	probably damaging	1.00
R4302:Igsf10	UTSW	3	59,226,171 (GRCm39)	missense	probably damaging	1.00
R4404:Igsf10	UTSW	3	59,236,972 (GRCm39)	missense	probably benign	0.04
R4575:Igsf10	UTSW	3	59,237,521 (GRCm39)	missense	probably benign
R4676:Igsf10	UTSW	3	59,233,370 (GRCm39)	missense	probably benign	0.23
R4700:Igsf10	UTSW	3	59,227,751 (GRCm39)	missense	probably damaging	0.99
R4765:Igsf10	UTSW	3	59,237,126 (GRCm39)	missense	probably benign	0.01
R4986:Igsf10	UTSW	3	59,236,027 (GRCm39)	missense	probably benign	0.24
R5012:Igsf10	UTSW	3	59,226,143 (GRCm39)	missense	probably damaging	1.00
R5070:Igsf10	UTSW	3	59,235,714 (GRCm39)	missense	probably benign	0.02
R5083:Igsf10	UTSW	3	59,233,694 (GRCm39)	missense	probably damaging	1.00
R5336:Igsf10	UTSW	3	59,227,553 (GRCm39)	missense	probably damaging	1.00
R5462:Igsf10	UTSW	3	59,233,175 (GRCm39)	missense	probably damaging	1.00
R5648:Igsf10	UTSW	3	59,235,574 (GRCm39)	missense	probably benign	0.01
R5810:Igsf10	UTSW	3	59,226,492 (GRCm39)	missense	probably damaging	1.00
R5871:Igsf10	UTSW	3	59,237,832 (GRCm39)	missense	possibly damaging	0.83
R5880:Igsf10	UTSW	3	59,238,252 (GRCm39)	missense	probably damaging	1.00
R5935:Igsf10	UTSW	3	59,235,578 (GRCm39)	missense	probably benign	0.12
R5979:Igsf10	UTSW	3	59,243,894 (GRCm39)	missense	probably damaging	1.00
R6145:Igsf10	UTSW	3	59,239,077 (GRCm39)	missense	possibly damaging	0.83
R6222:Igsf10	UTSW	3	59,226,336 (GRCm39)	missense	possibly damaging	0.90
R6224:Igsf10	UTSW	3	59,232,931 (GRCm39)	missense	probably damaging	1.00
R6264:Igsf10	UTSW	3	59,235,928 (GRCm39)	missense	possibly damaging	0.88
R6336:Igsf10	UTSW	3	59,237,760 (GRCm39)	missense	probably benign	0.00
R6490:Igsf10	UTSW	3	59,236,992 (GRCm39)	missense	probably benign	0.06
R6785:Igsf10	UTSW	3	59,226,665 (GRCm39)	missense	probably damaging	1.00
R6873:Igsf10	UTSW	3	59,235,865 (GRCm39)	missense	probably benign
R6889:Igsf10	UTSW	3	59,239,354 (GRCm39)	missense	probably benign
R7024:Igsf10	UTSW	3	59,239,122 (GRCm39)	missense	probably benign	0.00
R7056:Igsf10	UTSW	3	59,238,501 (GRCm39)	missense	probably damaging	1.00
R7128:Igsf10	UTSW	3	59,236,326 (GRCm39)	missense	probably benign
R7251:Igsf10	UTSW	3	59,226,875 (GRCm39)	missense	probably damaging	1.00
R7313:Igsf10	UTSW	3	59,236,837 (GRCm39)	missense	probably benign	0.05
R7340:Igsf10	UTSW	3	59,233,189 (GRCm39)	missense	probably damaging	1.00
R7447:Igsf10	UTSW	3	59,239,222 (GRCm39)	missense	probably benign	0.39
R7506:Igsf10	UTSW	3	59,226,775 (GRCm39)	missense	probably damaging	1.00
R7678:Igsf10	UTSW	3	59,226,761 (GRCm39)	missense	possibly damaging	0.81
R7695:Igsf10	UTSW	3	59,233,612 (GRCm39)	missense	probably damaging	1.00
R7709:Igsf10	UTSW	3	59,238,964 (GRCm39)	missense	probably damaging	0.96
R7749:Igsf10	UTSW	3	59,236,549 (GRCm39)	missense	possibly damaging	0.88
R7808:Igsf10	UTSW	3	59,235,489 (GRCm39)	missense	probably benign	0.00
R7850:Igsf10	UTSW	3	59,227,053 (GRCm39)	missense	probably benign	0.33
R7879:Igsf10	UTSW	3	59,238,145 (GRCm39)	missense	probably damaging	1.00
R7886:Igsf10	UTSW	3	59,235,748 (GRCm39)	missense	probably benign	0.01
R7891:Igsf10	UTSW	3	59,235,832 (GRCm39)	nonsense	probably null
R7946:Igsf10	UTSW	3	59,227,125 (GRCm39)	missense	possibly damaging	0.69
R7948:Igsf10	UTSW	3	59,239,279 (GRCm39)	missense	probably benign	0.02
R8004:Igsf10	UTSW	3	59,237,130 (GRCm39)	missense	probably benign	0.01
R8096:Igsf10	UTSW	3	59,236,380 (GRCm39)	missense	probably damaging	0.98
R8141:Igsf10	UTSW	3	59,237,949 (GRCm39)	missense	probably damaging	0.96
R8183:Igsf10	UTSW	3	59,238,036 (GRCm39)	missense	probably benign	0.04
R8203:Igsf10	UTSW	3	59,236,254 (GRCm39)	missense	probably benign	0.11
R8325:Igsf10	UTSW	3	59,225,954 (GRCm39)	missense	probably damaging	0.96
R8350:Igsf10	UTSW	3	59,238,949 (GRCm39)	missense	probably damaging	1.00
R8387:Igsf10	UTSW	3	59,236,564 (GRCm39)	missense	probably damaging	1.00
R8488:Igsf10	UTSW	3	59,227,431 (GRCm39)	missense	probably damaging	1.00
R8697:Igsf10	UTSW	3	59,226,308 (GRCm39)	missense	probably benign	0.02
R8786:Igsf10	UTSW	3	59,238,063 (GRCm39)	missense	probably benign	0.25
R8804:Igsf10	UTSW	3	59,243,876 (GRCm39)	missense	probably damaging	1.00
R8886:Igsf10	UTSW	3	59,237,410 (GRCm39)	missense	probably benign	0.00
R8902:Igsf10	UTSW	3	59,243,633 (GRCm39)	missense	probably benign	0.00
R8906:Igsf10	UTSW	3	59,233,739 (GRCm39)	missense	probably benign	0.01
R8917:Igsf10	UTSW	3	59,226,888 (GRCm39)	missense	possibly damaging	0.69
R9051:Igsf10	UTSW	3	59,236,668 (GRCm39)	missense	probably benign	0.00
R9178:Igsf10	UTSW	3	59,233,480 (GRCm39)	missense	possibly damaging	0.69
R9228:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9230:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9231:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9232:Igsf10	UTSW	3	59,243,843 (GRCm39)	missense	probably damaging	1.00
R9417:Igsf10	UTSW	3	59,236,526 (GRCm39)	missense	possibly damaging	0.94
R9609:Igsf10	UTSW	3	59,226,869 (GRCm39)	missense	probably damaging	1.00
R9631:Igsf10	UTSW	3	59,237,904 (GRCm39)	missense	probably damaging	1.00
R9689:Igsf10	UTSW	3	59,233,624 (GRCm39)	missense	probably damaging	1.00
R9762:Igsf10	UTSW	3	59,237,106 (GRCm39)	missense	probably damaging	1.00
R9770:Igsf10	UTSW	3	59,227,199 (GRCm39)	missense	probably benign	0.07
R9798:Igsf10	UTSW	3	59,239,126 (GRCm39)	missense	probably damaging	1.00
Z1088:Igsf10	UTSW	3	59,237,359 (GRCm39)	missense	possibly damaging	0.59
Z1177:Igsf10	UTSW	3	59,237,026 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- TCCACAGAGCAGTTCATTGC -3'
(R):5'- CTGGATATTGTCTCTAGGCCTC -3'

Sequencing Primer
(F):5'- ATTGCTACAGGCTTGCCAAC -3'
(R):5'- GTCTCTAGGCCTCCATTAATCAATG -3'

Posted On

2018-03-15