Incidental Mutation 'R6291:Ep300'
| ID |
508464 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ep300
|
| Ensembl Gene |
ENSMUSG00000055024 |
| Gene Name |
E1A binding protein p300 |
| Synonyms |
p300, KAT3B |
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R6291 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
81470329-81536278 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 81532708 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 1649
(S1649T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066789
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068387]
|
| AlphaFold |
B2RWS6 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000068387
AA Change: S1649T
|
| SMART Domains |
Protein: ENSMUSP00000066789
Gene: ENSMUSG00000055024
AA Change: S1649T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
242 |
N/A |
INTRINSIC |
|
low complexity region
|
296 |
309 |
N/A |
INTRINSIC |
|
ZnF_TAZ
|
333 |
418 |
2.85e-32 |
SMART |
|
low complexity region
|
475 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
503 |
N/A |
INTRINSIC |
|
Pfam:KIX
|
567 |
647 |
7.2e-44 |
PFAM |
|
low complexity region
|
722 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
831 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
852 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
924 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
1024 |
1039 |
N/A |
INTRINSIC |
|
BROMO
|
1047 |
1157 |
6.36e-42 |
SMART |
|
Blast:KAT11
|
1227 |
1300 |
9e-22 |
BLAST |
|
KAT11
|
1305 |
1610 |
1.19e-140 |
SMART |
|
ZnF_ZZ
|
1663 |
1704 |
2.67e-15 |
SMART |
|
ZnF_TAZ
|
1728 |
1806 |
5.53e-30 |
SMART |
|
low complexity region
|
1810 |
1836 |
N/A |
INTRINSIC |
|
low complexity region
|
1847 |
1881 |
N/A |
INTRINSIC |
|
low complexity region
|
1902 |
1927 |
N/A |
INTRINSIC |
|
low complexity region
|
1962 |
1979 |
N/A |
INTRINSIC |
|
Pfam:Creb_binding
|
1993 |
2099 |
3.5e-37 |
PFAM |
|
low complexity region
|
2146 |
2158 |
N/A |
INTRINSIC |
|
low complexity region
|
2187 |
2203 |
N/A |
INTRINSIC |
|
low complexity region
|
2205 |
2244 |
N/A |
INTRINSIC |
|
low complexity region
|
2254 |
2265 |
N/A |
INTRINSIC |
|
low complexity region
|
2303 |
2346 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2405 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000187776
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206431
|
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.6%
- 20x: 96.3%
|
| Validation Efficiency |
98% (86/88) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for a targeted null mutation exhibit defects of the heart, lung, and small intestine and die at midgestation; heterozygotes also show some embryonic loss. Heterozygotes for an acetyltransferase-negative mutation die by the neonatal period. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc12 |
C |
T |
8: 87,293,173 (GRCm39) |
G5D |
possibly damaging |
Het |
| Adamts9 |
T |
C |
6: 92,867,101 (GRCm39) |
K95R |
probably damaging |
Het |
| Adap1 |
G |
T |
5: 139,259,246 (GRCm39) |
L314M |
probably benign |
Het |
| Alkbh1 |
T |
A |
12: 87,475,864 (GRCm39) |
E306V |
possibly damaging |
Het |
| Alpk2 |
T |
A |
18: 65,438,972 (GRCm39) |
D1274V |
possibly damaging |
Het |
| Ankrd31 |
A |
C |
13: 97,014,746 (GRCm39) |
K1188N |
possibly damaging |
Het |
| Aox1 |
T |
A |
1: 58,369,965 (GRCm39) |
M759K |
probably damaging |
Het |
| Atp13a3 |
T |
A |
16: 30,155,061 (GRCm39) |
D961V |
probably damaging |
Het |
| Bcl11a |
G |
A |
11: 24,108,321 (GRCm39) |
G100R |
probably damaging |
Het |
| Bpifc |
G |
A |
10: 85,812,122 (GRCm39) |
A362V |
probably damaging |
Het |
| Btaf1 |
C |
T |
19: 36,950,408 (GRCm39) |
T546I |
probably benign |
Het |
| Casd1 |
C |
A |
6: 4,619,834 (GRCm39) |
P193Q |
probably damaging |
Het |
| Cdhr1 |
T |
C |
14: 36,811,422 (GRCm39) |
T230A |
probably benign |
Het |
| Celsr3 |
T |
G |
9: 108,706,041 (GRCm39) |
D841E |
probably damaging |
Het |
| Cenpj |
T |
C |
14: 56,789,433 (GRCm39) |
D872G |
probably benign |
Het |
| Cep95 |
G |
T |
11: 106,706,422 (GRCm39) |
A559S |
probably damaging |
Het |
| Chpt1 |
A |
T |
10: 88,311,306 (GRCm39) |
C62* |
probably null |
Het |
| Cspg4b |
T |
A |
13: 113,456,981 (GRCm39) |
I1009N |
possibly damaging |
Het |
| Cspp1 |
A |
G |
1: 10,134,559 (GRCm39) |
K103R |
probably damaging |
Het |
| Ctla4 |
T |
C |
1: 60,951,837 (GRCm39) |
V122A |
probably benign |
Het |
| Cyp3a11 |
A |
G |
5: 145,799,237 (GRCm39) |
F317L |
possibly damaging |
Het |
| Daam1 |
T |
C |
12: 71,993,025 (GRCm39) |
L338P |
unknown |
Het |
| Dcc |
T |
A |
18: 71,815,238 (GRCm39) |
I379L |
probably benign |
Het |
| Dennd2c |
C |
A |
3: 103,038,925 (GRCm39) |
C24* |
probably null |
Het |
| Dnai3 |
G |
A |
3: 145,772,648 (GRCm39) |
S466L |
probably benign |
Het |
| Dnajc12 |
A |
G |
10: 63,233,053 (GRCm39) |
I65V |
probably benign |
Het |
| Dock3 |
T |
A |
9: 106,785,631 (GRCm39) |
M208L |
probably benign |
Het |
| Dsg1b |
T |
C |
18: 20,537,848 (GRCm39) |
I588T |
possibly damaging |
Het |
| Eif1b |
T |
C |
9: 120,323,206 (GRCm39) |
L22S |
probably benign |
Het |
| Eps15 |
CAAA |
CAA |
4: 109,162,900 (GRCm39) |
|
probably null |
Het |
| Ercc6 |
A |
T |
14: 32,291,943 (GRCm39) |
E1102D |
probably benign |
Het |
| Gsdmc3 |
T |
C |
15: 63,732,090 (GRCm39) |
N312S |
probably benign |
Het |
| Guca2b |
A |
T |
4: 119,514,890 (GRCm39) |
L57Q |
probably damaging |
Het |
| Heatr5b |
G |
T |
17: 79,069,526 (GRCm39) |
H1740Q |
probably benign |
Het |
| Hecw1 |
G |
A |
13: 14,697,592 (GRCm39) |
|
probably benign |
Het |
| Icam5 |
A |
G |
9: 20,948,217 (GRCm39) |
H675R |
probably benign |
Het |
| Il18rap |
T |
C |
1: 40,564,049 (GRCm39) |
F56L |
probably benign |
Het |
| Iqgap3 |
T |
A |
3: 87,997,037 (GRCm39) |
|
probably null |
Het |
| Itsn1 |
T |
C |
16: 91,664,984 (GRCm39) |
|
probably benign |
Het |
| Jakmip3 |
A |
T |
7: 138,622,585 (GRCm39) |
D315V |
probably damaging |
Het |
| Kif24 |
A |
G |
4: 41,413,959 (GRCm39) |
Y328H |
probably damaging |
Het |
| Kmt2a |
A |
T |
9: 44,744,171 (GRCm39) |
|
probably benign |
Het |
| Kng1 |
A |
G |
16: 22,898,475 (GRCm39) |
E625G |
probably damaging |
Het |
| Man2b1 |
C |
T |
8: 85,823,675 (GRCm39) |
T973I |
probably benign |
Het |
| Masp2 |
G |
A |
4: 148,687,210 (GRCm39) |
V31M |
probably damaging |
Het |
| Myo18b |
C |
T |
5: 113,013,601 (GRCm39) |
R785H |
possibly damaging |
Het |
| Naa15 |
G |
A |
3: 51,350,212 (GRCm39) |
G103D |
probably damaging |
Het |
| Or4f15 |
A |
G |
2: 111,813,969 (GRCm39) |
V150A |
probably benign |
Het |
| Or5m11b |
A |
G |
2: 85,805,926 (GRCm39) |
Y113C |
probably damaging |
Het |
| Or7e177 |
T |
A |
9: 20,211,899 (GRCm39) |
D134E |
probably damaging |
Het |
| Papln |
A |
G |
12: 83,829,789 (GRCm39) |
N970S |
probably benign |
Het |
| Pick1 |
T |
A |
15: 79,135,928 (GRCm39) |
|
probably null |
Het |
| Pigr |
A |
C |
1: 130,769,498 (GRCm39) |
D103A |
probably benign |
Het |
| Plekhf1 |
A |
C |
7: 37,921,029 (GRCm39) |
F180V |
possibly damaging |
Het |
| Plxnc1 |
A |
G |
10: 94,669,504 (GRCm39) |
|
probably null |
Het |
| Polr3f |
A |
G |
2: 144,376,308 (GRCm39) |
I136V |
probably damaging |
Het |
| Ppp2r2c |
T |
C |
5: 37,097,468 (GRCm39) |
M218T |
possibly damaging |
Het |
| Prox2 |
C |
T |
12: 85,136,420 (GRCm39) |
V466I |
probably damaging |
Het |
| Prrc2a |
G |
A |
17: 35,373,909 (GRCm39) |
L1479F |
probably damaging |
Het |
| Rbm24 |
T |
A |
13: 46,575,313 (GRCm39) |
|
probably null |
Het |
| Rcc1l |
A |
T |
5: 134,195,560 (GRCm39) |
|
probably null |
Het |
| Ripk4 |
A |
C |
16: 97,556,323 (GRCm39) |
L140R |
probably damaging |
Het |
| Rmnd1 |
A |
T |
10: 4,372,135 (GRCm39) |
L188Q |
probably damaging |
Het |
| Rnf170 |
C |
T |
8: 26,630,992 (GRCm39) |
P249S |
probably damaging |
Het |
| Rras |
A |
G |
7: 44,667,595 (GRCm39) |
|
probably null |
Het |
| Rsf1 |
G |
A |
7: 97,229,117 (GRCm39) |
|
probably benign |
Het |
| Scn7a |
T |
A |
2: 66,530,458 (GRCm39) |
D629V |
probably damaging |
Het |
| Sipa1l3 |
A |
G |
7: 29,087,558 (GRCm39) |
S556P |
probably damaging |
Het |
| Smarca2 |
C |
T |
19: 26,608,292 (GRCm39) |
A117V |
probably damaging |
Het |
| Snca |
C |
T |
6: 60,792,702 (GRCm39) |
A69T |
probably damaging |
Het |
| Snx2 |
T |
C |
18: 53,342,737 (GRCm39) |
|
probably null |
Het |
| Spp1 |
T |
A |
5: 104,587,242 (GRCm39) |
S109T |
possibly damaging |
Het |
| Stoml3 |
T |
C |
3: 53,414,937 (GRCm39) |
L243P |
probably damaging |
Het |
| Susd2 |
A |
G |
10: 75,473,408 (GRCm39) |
F789L |
possibly damaging |
Het |
| Sycp1 |
A |
G |
3: 102,816,277 (GRCm39) |
M419T |
probably damaging |
Het |
| Thoc1 |
T |
C |
18: 9,993,330 (GRCm39) |
V563A |
probably benign |
Het |
| Tmprss11g |
T |
C |
5: 86,635,281 (GRCm39) |
I398V |
probably damaging |
Het |
| Tox3 |
A |
G |
8: 90,975,566 (GRCm39) |
L355P |
probably damaging |
Het |
| Tpp1 |
A |
G |
7: 105,396,223 (GRCm39) |
I492T |
probably benign |
Het |
| Trim21 |
A |
T |
7: 102,213,289 (GRCm39) |
L3Q |
probably damaging |
Het |
| Ttn |
A |
C |
2: 76,738,080 (GRCm39) |
V4153G |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,744,638 (GRCm39) |
|
probably benign |
Het |
| Unc80 |
A |
G |
1: 66,560,756 (GRCm39) |
E828G |
possibly damaging |
Het |
| Vav3 |
A |
G |
3: 109,416,170 (GRCm39) |
N263S |
possibly damaging |
Het |
| Vmn1r183 |
A |
C |
7: 23,754,982 (GRCm39) |
T262P |
possibly damaging |
Het |
| Vmn2r67 |
G |
A |
7: 84,799,142 (GRCm39) |
P522S |
possibly damaging |
Het |
| Vps35 |
T |
A |
8: 86,026,086 (GRCm39) |
M1L |
probably benign |
Het |
| Xpo7 |
A |
T |
14: 70,942,130 (GRCm39) |
L79* |
probably null |
Het |
| Zc3h14 |
G |
A |
12: 98,726,087 (GRCm39) |
R324H |
probably damaging |
Het |
| Zfp330 |
T |
C |
8: 83,499,613 (GRCm39) |
T6A |
probably damaging |
Het |
| Zfp948 |
T |
A |
17: 21,807,286 (GRCm39) |
H159Q |
unknown |
Het |
|
| Other mutations in Ep300 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Ep300
|
APN |
15 |
81,525,619 (GRCm39) |
missense |
unknown |
|
|
IGL01128:Ep300
|
APN |
15 |
81,514,207 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01151:Ep300
|
APN |
15 |
81,507,673 (GRCm39) |
intron |
probably benign |
|
|
IGL01414:Ep300
|
APN |
15 |
81,511,467 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01564:Ep300
|
APN |
15 |
81,516,665 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01875:Ep300
|
APN |
15 |
81,524,224 (GRCm39) |
missense |
unknown |
|
|
IGL01945:Ep300
|
APN |
15 |
81,500,310 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02022:Ep300
|
APN |
15 |
81,495,638 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02115:Ep300
|
APN |
15 |
81,533,019 (GRCm39) |
missense |
unknown |
|
|
IGL02129:Ep300
|
APN |
15 |
81,470,837 (GRCm39) |
missense |
unknown |
|
|
IGL02145:Ep300
|
APN |
15 |
81,485,367 (GRCm39) |
missense |
unknown |
|
|
IGL02149:Ep300
|
APN |
15 |
81,512,621 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02165:Ep300
|
APN |
15 |
81,525,592 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02226:Ep300
|
APN |
15 |
81,497,613 (GRCm39) |
missense |
unknown |
|
|
IGL02610:Ep300
|
APN |
15 |
81,485,723 (GRCm39) |
missense |
unknown |
|
|
IGL02731:Ep300
|
APN |
15 |
81,532,615 (GRCm39) |
missense |
unknown |
|
|
IGL03239:Ep300
|
APN |
15 |
81,525,589 (GRCm39) |
missense |
unknown |
|
|
BB001:Ep300
|
UTSW |
15 |
81,533,703 (GRCm39) |
missense |
unknown |
|
|
BB011:Ep300
|
UTSW |
15 |
81,533,703 (GRCm39) |
missense |
unknown |
|
|
R0077:Ep300
|
UTSW |
15 |
81,525,514 (GRCm39) |
missense |
unknown |
|
|
R0145:Ep300
|
UTSW |
15 |
81,500,328 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0244:Ep300
|
UTSW |
15 |
81,524,329 (GRCm39) |
missense |
unknown |
|
|
R0390:Ep300
|
UTSW |
15 |
81,524,317 (GRCm39) |
missense |
unknown |
|
|
R0534:Ep300
|
UTSW |
15 |
81,485,097 (GRCm39) |
splice site |
probably benign |
|
|
R0671:Ep300
|
UTSW |
15 |
81,500,335 (GRCm39) |
unclassified |
probably benign |
|
|
R0840:Ep300
|
UTSW |
15 |
81,529,134 (GRCm39) |
missense |
unknown |
|
|
R1166:Ep300
|
UTSW |
15 |
81,514,265 (GRCm39) |
unclassified |
probably benign |
|
|
R1737:Ep300
|
UTSW |
15 |
81,510,548 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1893:Ep300
|
UTSW |
15 |
81,515,847 (GRCm39) |
unclassified |
probably benign |
|
|
R2136:Ep300
|
UTSW |
15 |
81,524,648 (GRCm39) |
missense |
unknown |
|
|
R3427:Ep300
|
UTSW |
15 |
81,485,480 (GRCm39) |
missense |
unknown |
|
|
R3757:Ep300
|
UTSW |
15 |
81,532,790 (GRCm39) |
missense |
unknown |
|
|
R3892:Ep300
|
UTSW |
15 |
81,504,198 (GRCm39) |
unclassified |
probably benign |
|
|
R4554:Ep300
|
UTSW |
15 |
81,485,631 (GRCm39) |
missense |
unknown |
|
|
R4575:Ep300
|
UTSW |
15 |
81,495,611 (GRCm39) |
unclassified |
probably benign |
|
|
R4575:Ep300
|
UTSW |
15 |
81,533,210 (GRCm39) |
missense |
unknown |
|
|
R4577:Ep300
|
UTSW |
15 |
81,495,611 (GRCm39) |
unclassified |
probably benign |
|
|
R4577:Ep300
|
UTSW |
15 |
81,533,210 (GRCm39) |
missense |
unknown |
|
|
R4578:Ep300
|
UTSW |
15 |
81,495,611 (GRCm39) |
unclassified |
probably benign |
|
|
R4578:Ep300
|
UTSW |
15 |
81,533,210 (GRCm39) |
missense |
unknown |
|
|
R5021:Ep300
|
UTSW |
15 |
81,524,224 (GRCm39) |
missense |
unknown |
|
|
R5366:Ep300
|
UTSW |
15 |
81,500,301 (GRCm39) |
missense |
probably benign |
0.24 |
|
R5372:Ep300
|
UTSW |
15 |
81,521,031 (GRCm39) |
missense |
unknown |
|
|
R5393:Ep300
|
UTSW |
15 |
81,515,819 (GRCm39) |
unclassified |
probably benign |
|
|
R5410:Ep300
|
UTSW |
15 |
81,533,055 (GRCm39) |
missense |
unknown |
|
|
R5571:Ep300
|
UTSW |
15 |
81,527,418 (GRCm39) |
intron |
probably benign |
|
|
R5701:Ep300
|
UTSW |
15 |
81,485,696 (GRCm39) |
missense |
unknown |
|
|
R5772:Ep300
|
UTSW |
15 |
81,524,115 (GRCm39) |
intron |
probably benign |
|
|
R5825:Ep300
|
UTSW |
15 |
81,495,673 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5917:Ep300
|
UTSW |
15 |
81,512,808 (GRCm39) |
unclassified |
probably benign |
|
|
R5991:Ep300
|
UTSW |
15 |
81,532,667 (GRCm39) |
missense |
unknown |
|
|
R6019:Ep300
|
UTSW |
15 |
81,525,583 (GRCm39) |
missense |
unknown |
|
|
R6144:Ep300
|
UTSW |
15 |
81,485,435 (GRCm39) |
missense |
unknown |
|
|
R6292:Ep300
|
UTSW |
15 |
81,500,935 (GRCm39) |
unclassified |
probably benign |
|
|
R6599:Ep300
|
UTSW |
15 |
81,470,914 (GRCm39) |
missense |
unknown |
|
|
R6804:Ep300
|
UTSW |
15 |
81,525,512 (GRCm39) |
nonsense |
probably null |
|
|
R6925:Ep300
|
UTSW |
15 |
81,534,182 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7327:Ep300
|
UTSW |
15 |
81,511,515 (GRCm39) |
missense |
unknown |
|
|
R7378:Ep300
|
UTSW |
15 |
81,534,746 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7388:Ep300
|
UTSW |
15 |
81,532,567 (GRCm39) |
missense |
unknown |
|
|
R7419:Ep300
|
UTSW |
15 |
81,532,715 (GRCm39) |
missense |
unknown |
|
|
R7498:Ep300
|
UTSW |
15 |
81,524,044 (GRCm39) |
missense |
unknown |
|
|
R7584:Ep300
|
UTSW |
15 |
81,512,627 (GRCm39) |
missense |
unknown |
|
|
R7605:Ep300
|
UTSW |
15 |
81,505,353 (GRCm39) |
missense |
unknown |
|
|
R7619:Ep300
|
UTSW |
15 |
81,492,399 (GRCm39) |
missense |
unknown |
|
|
R7699:Ep300
|
UTSW |
15 |
81,470,594 (GRCm39) |
start gained |
probably benign |
|
|
R7763:Ep300
|
UTSW |
15 |
81,470,784 (GRCm39) |
start gained |
probably benign |
|
|
R7775:Ep300
|
UTSW |
15 |
81,470,887 (GRCm39) |
missense |
unknown |
|
|
R7778:Ep300
|
UTSW |
15 |
81,470,887 (GRCm39) |
missense |
unknown |
|
|
R7862:Ep300
|
UTSW |
15 |
81,534,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7924:Ep300
|
UTSW |
15 |
81,533,703 (GRCm39) |
missense |
unknown |
|
|
R8155:Ep300
|
UTSW |
15 |
81,505,269 (GRCm39) |
missense |
unknown |
|
|
R8259:Ep300
|
UTSW |
15 |
81,523,218 (GRCm39) |
missense |
unknown |
|
|
R8276:Ep300
|
UTSW |
15 |
81,534,229 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8331:Ep300
|
UTSW |
15 |
81,485,411 (GRCm39) |
missense |
unknown |
|
|
R8554:Ep300
|
UTSW |
15 |
81,523,228 (GRCm39) |
missense |
unknown |
|
|
R9019:Ep300
|
UTSW |
15 |
81,532,730 (GRCm39) |
missense |
unknown |
|
|
R9128:Ep300
|
UTSW |
15 |
81,533,946 (GRCm39) |
missense |
unknown |
|
|
R9379:Ep300
|
UTSW |
15 |
81,532,760 (GRCm39) |
missense |
unknown |
|
|
R9380:Ep300
|
UTSW |
15 |
81,500,245 (GRCm39) |
missense |
unknown |
|
|
R9484:Ep300
|
UTSW |
15 |
81,521,026 (GRCm39) |
missense |
unknown |
|
|
R9659:Ep300
|
UTSW |
15 |
81,505,273 (GRCm39) |
missense |
unknown |
|
|
R9690:Ep300
|
UTSW |
15 |
81,520,396 (GRCm39) |
missense |
unknown |
|
|
R9721:Ep300
|
UTSW |
15 |
81,492,516 (GRCm39) |
missense |
unknown |
|
|
RF020:Ep300
|
UTSW |
15 |
81,470,772 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Ep300
|
UTSW |
15 |
81,514,298 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CAGTGGCATTGCAGTTCGAAAG -3'
(R):5'- GGGCAGAGGTTTGTAACACATG -3'
Sequencing Primer
(F):5'- GCATTGCAGTTCGAAAGTCACAATG -3'
(R):5'- GGCAGAGGTTTGTAACACATGTTTAC -3'
|
| Posted On |
2018-03-15 |
Incidental Mutation