Incidental Mutation 'R6298:Insrr'
| ID |
508876 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Insrr
|
| Ensembl Gene |
ENSMUSG00000005640 |
| Gene Name |
insulin receptor-related receptor |
| Synonyms |
|
| MMRRC Submission |
044408-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.285)
|
| Stock # |
R6298 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
87704258-87723408 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 87720272 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 970
(D970G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000103208
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029711]
[ENSMUST00000029714]
[ENSMUST00000090981]
[ENSMUST00000107582]
|
| AlphaFold |
Q9WTL4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000029711
AA Change: D970G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000029711
Gene: ENSMUSG00000005640
AA Change: D970G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:Recep_L_domain
|
47 |
159 |
1.8e-25 |
PFAM |
|
FU
|
225 |
268 |
9.54e-11 |
SMART |
|
Pfam:Recep_L_domain
|
346 |
460 |
3.8e-28 |
PFAM |
|
FN3
|
483 |
586 |
9.19e-1 |
SMART |
|
FN3
|
605 |
798 |
6.45e-5 |
SMART |
|
FN3
|
816 |
899 |
6.35e-4 |
SMART |
|
TyrKc
|
979 |
1246 |
4.61e-128 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029714
|
| SMART Domains |
Protein: ENSMUSP00000029714
Gene: ENSMUSG00000028073
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
78 |
N/A |
INTRINSIC |
|
EGF
|
102 |
130 |
3.82e-2 |
SMART |
|
EGF_like
|
132 |
173 |
2.92e1 |
SMART |
|
EGF_like
|
146 |
185 |
1.92e0 |
SMART |
|
EGF_like
|
189 |
246 |
1.99e0 |
SMART |
|
EGF
|
217 |
258 |
1.04e1 |
SMART |
|
EGF_Lam
|
274 |
313 |
1.21e-4 |
SMART |
|
EGF
|
312 |
344 |
4.03e-1 |
SMART |
|
EGF_Lam
|
361 |
402 |
1.33e-1 |
SMART |
|
EGF
|
401 |
433 |
1.18e-2 |
SMART |
|
EGF_like
|
449 |
488 |
1.72e0 |
SMART |
|
EGF
|
487 |
519 |
6.92e0 |
SMART |
|
EGF_Lam
|
535 |
574 |
2.08e-3 |
SMART |
|
EGF
|
573 |
605 |
5.49e-3 |
SMART |
|
EGF_Lam
|
620 |
660 |
1.58e-3 |
SMART |
|
EGF
|
659 |
691 |
3.1e-2 |
SMART |
|
EGF
|
702 |
734 |
2.53e1 |
SMART |
|
transmembrane domain
|
754 |
776 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
993 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1019 |
1031 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000090981
|
| SMART Domains |
Protein: ENSMUSP00000088503
Gene: ENSMUSG00000028073
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
low complexity region
|
67 |
78 |
N/A |
INTRINSIC |
|
EGF
|
102 |
130 |
3.82e-2 |
SMART |
|
EGF_like
|
132 |
173 |
2.92e1 |
SMART |
|
EGF_like
|
146 |
185 |
1.92e0 |
SMART |
|
EGF_like
|
189 |
246 |
1.99e0 |
SMART |
|
EGF
|
217 |
258 |
1.04e1 |
SMART |
|
EGF_Lam
|
274 |
313 |
1.21e-4 |
SMART |
|
EGF
|
312 |
344 |
4.03e-1 |
SMART |
|
EGF_Lam
|
361 |
402 |
1.33e-1 |
SMART |
|
EGF
|
401 |
433 |
1.18e-2 |
SMART |
|
EGF_like
|
449 |
488 |
1.72e0 |
SMART |
|
EGF
|
487 |
519 |
6.92e0 |
SMART |
|
EGF_Lam
|
535 |
574 |
2.08e-3 |
SMART |
|
EGF
|
573 |
605 |
5.49e-3 |
SMART |
|
EGF_Lam
|
620 |
660 |
1.58e-3 |
SMART |
|
EGF
|
659 |
691 |
3.1e-2 |
SMART |
|
EGF
|
702 |
734 |
2.53e1 |
SMART |
|
transmembrane domain
|
754 |
776 |
N/A |
INTRINSIC |
|
low complexity region
|
809 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
954 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
993 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1019 |
1031 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107582
AA Change: D970G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000103208
Gene: ENSMUSG00000005640
AA Change: D970G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
Pfam:Recep_L_domain
|
47 |
159 |
7.7e-25 |
PFAM |
|
FU
|
225 |
268 |
9.54e-11 |
SMART |
|
Pfam:Recep_L_domain
|
346 |
460 |
1.6e-28 |
PFAM |
|
FN3
|
483 |
586 |
9.19e-1 |
SMART |
|
FN3
|
605 |
798 |
6.45e-5 |
SMART |
|
FN3
|
816 |
899 |
6.35e-4 |
SMART |
|
TyrKc
|
979 |
1246 |
4.61e-128 |
SMART |
|
| Meta Mutation Damage Score |
0.3786 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
98% (79/81) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit no anomalies in pancreatic islet morphology, beta-cell mass or pancreatic secretory function. This mutation in combination with Insr mutant mice does not affect the diabetes predisposition of Insr mutant mice. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abtb2 |
A |
T |
2: 103,539,833 (GRCm39) |
M733L |
probably benign |
Het |
| Acss3 |
G |
A |
10: 106,920,717 (GRCm39) |
P131L |
probably damaging |
Het |
| Adgrv1 |
T |
A |
13: 81,539,886 (GRCm39) |
I5678F |
probably benign |
Het |
| Aff1 |
C |
T |
5: 103,902,586 (GRCm39) |
L6F |
possibly damaging |
Het |
| Ank3 |
G |
T |
10: 69,686,006 (GRCm39) |
R273L |
probably damaging |
Het |
| Anks1b |
G |
A |
10: 90,516,699 (GRCm39) |
G898D |
probably damaging |
Het |
| Anxa11 |
C |
T |
14: 25,873,158 (GRCm39) |
P131S |
unknown |
Het |
| Ap4e1 |
T |
A |
2: 126,889,035 (GRCm39) |
M500K |
probably benign |
Het |
| Bag3 |
T |
C |
7: 128,141,922 (GRCm39) |
S138P |
probably damaging |
Het |
| Capn9 |
T |
C |
8: 125,344,193 (GRCm39) |
V670A |
probably benign |
Het |
| Ccne2 |
T |
A |
4: 11,199,306 (GRCm39) |
W236R |
probably damaging |
Het |
| Cdh23 |
A |
T |
10: 60,262,451 (GRCm39) |
Y702* |
probably null |
Het |
| Chd1l |
G |
A |
3: 97,494,483 (GRCm39) |
A399V |
probably damaging |
Het |
| Cit |
A |
T |
5: 116,086,124 (GRCm39) |
E896V |
probably damaging |
Het |
| Cntln |
T |
A |
4: 85,014,998 (GRCm39) |
N1096K |
probably damaging |
Het |
| Cntnap5c |
T |
C |
17: 58,411,747 (GRCm39) |
C544R |
probably damaging |
Het |
| Csf1 |
A |
T |
3: 107,655,675 (GRCm39) |
L452Q |
possibly damaging |
Het |
| Cts8 |
T |
A |
13: 61,397,037 (GRCm39) |
K294N |
possibly damaging |
Het |
| Dcakd |
T |
G |
11: 102,890,618 (GRCm39) |
E56D |
possibly damaging |
Het |
| Dnah17 |
T |
C |
11: 117,998,987 (GRCm39) |
I929V |
probably benign |
Het |
| Dnah2 |
G |
T |
11: 69,382,467 (GRCm39) |
H1214Q |
probably benign |
Het |
| Dock9 |
T |
C |
14: 121,872,006 (GRCm39) |
D536G |
probably damaging |
Het |
| Drc3 |
A |
G |
11: 60,284,596 (GRCm39) |
N467S |
possibly damaging |
Het |
| Dysf |
A |
G |
6: 84,084,118 (GRCm39) |
|
probably null |
Het |
| Ecpas |
T |
G |
4: 58,877,157 (GRCm39) |
T93P |
probably damaging |
Het |
| Evpl |
A |
T |
11: 116,121,748 (GRCm39) |
L378Q |
probably damaging |
Het |
| Fer1l4 |
A |
T |
2: 155,866,660 (GRCm39) |
H1520Q |
probably damaging |
Het |
| Fhod1 |
A |
T |
8: 106,063,780 (GRCm39) |
|
probably benign |
Het |
| Gabra1 |
T |
A |
11: 42,073,205 (GRCm39) |
|
probably benign |
Het |
| Gm10549 |
C |
A |
18: 33,597,358 (GRCm39) |
|
probably benign |
Het |
| Gm14137 |
A |
G |
2: 119,005,572 (GRCm39) |
T44A |
possibly damaging |
Het |
| H2bl1 |
T |
A |
13: 99,120,974 (GRCm39) |
R17S |
probably benign |
Het |
| Herc2 |
T |
C |
7: 55,841,013 (GRCm39) |
M3444T |
probably benign |
Het |
| Igsf5 |
T |
C |
16: 96,197,648 (GRCm39) |
S208P |
possibly damaging |
Het |
| Ino80b |
A |
G |
6: 83,102,066 (GRCm39) |
L12P |
possibly damaging |
Het |
| Iqcf4 |
G |
A |
9: 106,445,874 (GRCm39) |
A91V |
probably benign |
Het |
| Itga10 |
A |
G |
3: 96,564,078 (GRCm39) |
T911A |
probably benign |
Het |
| Katnip |
T |
C |
7: 125,469,869 (GRCm39) |
V1446A |
probably benign |
Het |
| Klhl30 |
A |
T |
1: 91,285,086 (GRCm39) |
D314V |
probably benign |
Het |
| Lpcat1 |
T |
C |
13: 73,659,074 (GRCm39) |
V330A |
possibly damaging |
Het |
| Myef2l |
T |
C |
3: 10,154,239 (GRCm39) |
I336T |
probably damaging |
Het |
| Nhlrc3 |
A |
T |
3: 53,359,944 (GRCm39) |
D306E |
possibly damaging |
Het |
| Notum |
T |
A |
11: 120,548,766 (GRCm39) |
I187F |
probably damaging |
Het |
| Nphp3 |
T |
C |
9: 103,892,640 (GRCm39) |
L288P |
probably damaging |
Het |
| Ntrk2 |
G |
T |
13: 59,019,570 (GRCm39) |
E394* |
probably null |
Het |
| Or6k2 |
T |
A |
1: 173,979,748 (GRCm39) |
V222D |
probably benign |
Het |
| Pbld2 |
A |
G |
10: 62,874,931 (GRCm39) |
K63E |
probably benign |
Het |
| Phc2 |
T |
C |
4: 128,641,982 (GRCm39) |
M768T |
possibly damaging |
Het |
| Pik3c2g |
G |
A |
6: 139,603,561 (GRCm39) |
C249Y |
probably damaging |
Het |
| Plod1 |
G |
A |
4: 148,000,772 (GRCm39) |
|
probably benign |
Het |
| Plscr2 |
A |
T |
9: 92,172,772 (GRCm39) |
T9S |
probably benign |
Het |
| Pnrc1 |
T |
A |
4: 33,246,315 (GRCm39) |
M215L |
probably benign |
Het |
| Prcp |
G |
T |
7: 92,577,841 (GRCm39) |
C370F |
probably damaging |
Het |
| Pter |
A |
G |
2: 12,983,205 (GRCm39) |
N70S |
probably damaging |
Het |
| Ptprt |
G |
T |
2: 161,395,779 (GRCm39) |
H1131Q |
probably damaging |
Het |
| Rasal2 |
T |
C |
1: 157,239,432 (GRCm39) |
D8G |
possibly damaging |
Het |
| Rcn2 |
A |
C |
9: 55,960,209 (GRCm39) |
K159Q |
probably benign |
Het |
| Rex2 |
T |
A |
4: 147,141,972 (GRCm39) |
C153* |
probably null |
Het |
| Rps6ka2 |
T |
C |
17: 7,437,766 (GRCm39) |
F8S |
possibly damaging |
Het |
| Samd9l |
A |
G |
6: 3,375,383 (GRCm39) |
L626S |
probably damaging |
Het |
| Sptb |
A |
G |
12: 76,667,428 (GRCm39) |
|
probably null |
Het |
| Srgap3 |
A |
T |
6: 112,793,571 (GRCm39) |
V135D |
probably damaging |
Het |
| Srsf7 |
T |
C |
17: 80,514,682 (GRCm39) |
|
probably benign |
Het |
| Tacc2 |
A |
G |
7: 130,228,255 (GRCm39) |
T1647A |
probably benign |
Het |
| Thap12 |
G |
T |
7: 98,352,612 (GRCm39) |
A6S |
probably damaging |
Het |
| Tmem33 |
T |
A |
5: 67,425,894 (GRCm39) |
L146* |
probably null |
Het |
| Trip13 |
C |
A |
13: 74,084,378 (GRCm39) |
E36* |
probably null |
Het |
| Vkorc1l1 |
T |
A |
5: 129,971,079 (GRCm39) |
C23S |
probably damaging |
Het |
| Vmn1r20 |
G |
A |
6: 57,409,112 (GRCm39) |
R146H |
probably benign |
Het |
| Vmn1r222 |
T |
A |
13: 23,416,965 (GRCm39) |
I83F |
probably benign |
Het |
| Vmn2r107 |
A |
T |
17: 20,576,044 (GRCm39) |
I125F |
probably benign |
Het |
| Vmn2r116 |
A |
G |
17: 23,605,736 (GRCm39) |
D216G |
probably damaging |
Het |
| Vwa3a |
C |
T |
7: 120,394,874 (GRCm39) |
T898I |
probably benign |
Het |
| Wdfy3 |
T |
C |
5: 102,116,812 (GRCm39) |
D76G |
probably damaging |
Het |
| Wdhd1 |
T |
C |
14: 47,510,579 (GRCm39) |
D148G |
possibly damaging |
Het |
| Xylt1 |
T |
C |
7: 117,255,960 (GRCm39) |
I844T |
probably damaging |
Het |
| Zfp106 |
A |
T |
2: 120,353,185 (GRCm39) |
V1535D |
probably damaging |
Het |
| Zfp385b |
A |
T |
2: 77,244,323 (GRCm39) |
L315Q |
possibly damaging |
Het |
| Zfp458 |
T |
A |
13: 67,404,870 (GRCm39) |
H523L |
probably damaging |
Het |
| Zfp712 |
T |
C |
13: 67,189,393 (GRCm39) |
H378R |
probably damaging |
Het |
| Zic1 |
T |
C |
9: 91,246,556 (GRCm39) |
Y172C |
probably damaging |
Het |
|
| Other mutations in Insrr |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00718:Insrr
|
APN |
3 |
87,720,981 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00801:Insrr
|
APN |
3 |
87,721,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Insrr
|
APN |
3 |
87,708,099 (GRCm39) |
nonsense |
probably null |
|
|
IGL01755:Insrr
|
APN |
3 |
87,721,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02100:Insrr
|
APN |
3 |
87,718,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02261:Insrr
|
APN |
3 |
87,708,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02366:Insrr
|
APN |
3 |
87,717,216 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02387:Insrr
|
APN |
3 |
87,720,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02478:Insrr
|
APN |
3 |
87,716,719 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL02550:Insrr
|
APN |
3 |
87,711,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02555:Insrr
|
APN |
3 |
87,721,124 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02673:Insrr
|
APN |
3 |
87,720,368 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02724:Insrr
|
APN |
3 |
87,716,879 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02798:Insrr
|
APN |
3 |
87,717,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02969:Insrr
|
APN |
3 |
87,721,498 (GRCm39) |
nonsense |
probably null |
|
|
IGL03073:Insrr
|
APN |
3 |
87,717,245 (GRCm39) |
splice site |
probably benign |
|
|
IGL03178:Insrr
|
APN |
3 |
87,709,848 (GRCm39) |
splice site |
probably null |
|
|
IGL03389:Insrr
|
APN |
3 |
87,716,038 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03399:Insrr
|
APN |
3 |
87,716,638 (GRCm39) |
missense |
probably null |
0.99 |
|
IGL02799:Insrr
|
UTSW |
3 |
87,720,888 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0011:Insrr
|
UTSW |
3 |
87,716,923 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0053:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0053:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0357:Insrr
|
UTSW |
3 |
87,715,953 (GRCm39) |
splice site |
probably null |
|
|
R0501:Insrr
|
UTSW |
3 |
87,717,991 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0504:Insrr
|
UTSW |
3 |
87,720,463 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0522:Insrr
|
UTSW |
3 |
87,708,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0555:Insrr
|
UTSW |
3 |
87,721,744 (GRCm39) |
splice site |
probably benign |
|
|
R0558:Insrr
|
UTSW |
3 |
87,718,288 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0599:Insrr
|
UTSW |
3 |
87,720,440 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1312:Insrr
|
UTSW |
3 |
87,707,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Insrr
|
UTSW |
3 |
87,711,369 (GRCm39) |
missense |
probably benign |
|
|
R1785:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R1786:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R1892:Insrr
|
UTSW |
3 |
87,721,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1950:Insrr
|
UTSW |
3 |
87,721,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2080:Insrr
|
UTSW |
3 |
87,721,598 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2094:Insrr
|
UTSW |
3 |
87,710,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2130:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2131:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2133:Insrr
|
UTSW |
3 |
87,717,879 (GRCm39) |
splice site |
probably null |
|
|
R2220:Insrr
|
UTSW |
3 |
87,716,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2259:Insrr
|
UTSW |
3 |
87,707,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2404:Insrr
|
UTSW |
3 |
87,709,974 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4027:Insrr
|
UTSW |
3 |
87,716,906 (GRCm39) |
missense |
probably benign |
|
|
R4042:Insrr
|
UTSW |
3 |
87,721,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4510:Insrr
|
UTSW |
3 |
87,715,978 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4511:Insrr
|
UTSW |
3 |
87,715,978 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4571:Insrr
|
UTSW |
3 |
87,708,194 (GRCm39) |
missense |
probably benign |
|
|
R4870:Insrr
|
UTSW |
3 |
87,718,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Insrr
|
UTSW |
3 |
87,722,572 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5393:Insrr
|
UTSW |
3 |
87,718,007 (GRCm39) |
splice site |
probably null |
|
|
R5685:Insrr
|
UTSW |
3 |
87,707,803 (GRCm39) |
splice site |
probably null |
|
|
R6039:Insrr
|
UTSW |
3 |
87,716,608 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6039:Insrr
|
UTSW |
3 |
87,716,608 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6047:Insrr
|
UTSW |
3 |
87,711,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6276:Insrr
|
UTSW |
3 |
87,707,826 (GRCm39) |
nonsense |
probably null |
|
|
R6726:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6727:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6728:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6796:Insrr
|
UTSW |
3 |
87,720,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7041:Insrr
|
UTSW |
3 |
87,722,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7169:Insrr
|
UTSW |
3 |
87,715,901 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7270:Insrr
|
UTSW |
3 |
87,710,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7340:Insrr
|
UTSW |
3 |
87,721,623 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7398:Insrr
|
UTSW |
3 |
87,716,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7473:Insrr
|
UTSW |
3 |
87,711,838 (GRCm39) |
splice site |
probably null |
|
|
R7815:Insrr
|
UTSW |
3 |
87,716,002 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8159:Insrr
|
UTSW |
3 |
87,707,735 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8289:Insrr
|
UTSW |
3 |
87,721,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8309:Insrr
|
UTSW |
3 |
87,717,749 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8312:Insrr
|
UTSW |
3 |
87,707,791 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8445:Insrr
|
UTSW |
3 |
87,720,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8917:Insrr
|
UTSW |
3 |
87,718,276 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8960:Insrr
|
UTSW |
3 |
87,720,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8989:Insrr
|
UTSW |
3 |
87,722,664 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9015:Insrr
|
UTSW |
3 |
87,720,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9202:Insrr
|
UTSW |
3 |
87,720,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9251:Insrr
|
UTSW |
3 |
87,717,391 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9327:Insrr
|
UTSW |
3 |
87,721,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9646:Insrr
|
UTSW |
3 |
87,721,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF022:Insrr
|
UTSW |
3 |
87,711,792 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Z1177:Insrr
|
UTSW |
3 |
87,708,134 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
Z1192:Insrr
|
UTSW |
3 |
87,709,886 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATAGACGCCTTTGTCCTGC -3'
(R):5'- AGGAATTCAACGCGTTCCC -3'
Sequencing Primer
(F):5'- GTGTGAGCCTGTAGTTACCAAAATC -3'
(R):5'- CAACGCGTTCCCGAGCG -3'
|
| Posted On |
2018-04-02 |
Incidental Mutation