Mutagenetix > Incidental Mutation

Incidental Mutation 'R6331:Ahnak'

510946

Institutional Source

Beutler Lab

Gene Symbol

Ahnak

Ensembl Gene

ENSMUSG00000069833

Gene Name

AHNAK nucleoprotein

Synonyms

DY6, 1110004P15Rik, 2310047C17Rik

MMRRC Submission

044485-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.313) question?

Stock #

R6331 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

8966648-9054278 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 8983989 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Leucine at position 1758 (M1758L)

Ref Sequence

ENSEMBL: ENSMUSP00000090633 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092955] [ENSMUST00000092956]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000092955

SMART Domains

Protein: ENSMUSP00000090632
Gene: ENSMUSG00000069833

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000092956
AA Change: M1758L

PolyPhen 2 Score 0.182 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000090633
Gene: ENSMUSG00000069833
AA Change: M1758L

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART
internal_repeat_2	163	1515	5.22e-182	PROSPERO
internal_repeat_1	224	2314	N/A	PROSPERO
internal_repeat_2	1532	3028	5.22e-182	PROSPERO
internal_repeat_1	2660	5095	N/A	PROSPERO
low complexity region	5336	5353	N/A	INTRINSIC
low complexity region	5493	5504	N/A	INTRINSIC
low complexity region	5580	5600	N/A	INTRINSIC
low complexity region	5620	5636	N/A	INTRINSIC

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.3%
20x: 97.8%

Validation Efficiency

100% (66/66)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 66 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
A2ml1	T	C	6: 128,529,199 (GRCm39)	D981G	probably damaging	Het
Abcc1	C	A	16: 14,282,920 (GRCm39)	A1132D	probably damaging	Het
Adamts12	A	G	15: 11,241,519 (GRCm39)	T364A	probably damaging	Het
Ak9	T	C	10: 41,258,825 (GRCm39)	V774A	probably damaging	Het
Ash1l	A	G	3: 88,915,172 (GRCm39)	E1934G	probably benign	Het
Atp2b2	C	T	6: 113,774,092 (GRCm39)	A341T	probably benign	Het
Bach2	G	T	4: 32,238,816 (GRCm39)		probably benign	Het
Bltp3a	T	C	17: 28,112,175 (GRCm39)	I1150T	probably benign	Het
Brd10	C	T	19: 29,695,147 (GRCm39)	V1449I	probably benign	Het
Ccdc102a	T	C	8: 95,638,144 (GRCm39)	T241A	probably benign	Het
Chd5	G	T	4: 152,466,865 (GRCm39)	R1627S	probably benign	Het
Clint1	T	C	11: 45,785,908 (GRCm39)	S322P	probably benign	Het
Dapk1	T	A	13: 60,877,256 (GRCm39)	C498*	probably null	Het
Diaph3	T	G	14: 87,103,976 (GRCm39)	S803R	probably damaging	Het
Dmp1	T	C	5: 104,354,991 (GRCm39)	L10P	probably damaging	Het
Gcc2	T	C	10: 58,107,287 (GRCm39)	V741A	probably benign	Het
Gldn	A	G	9: 54,194,162 (GRCm39)	M119V	probably benign	Het
Gucy1b1	A	G	3: 81,941,718 (GRCm39)	S574P	possibly damaging	Het
Hapln4	T	A	8: 70,537,073 (GRCm39)		probably benign	Het
Hars1	A	G	18: 36,904,385 (GRCm39)	V209A	probably benign	Het
Htt	T	A	5: 35,053,231 (GRCm39)	F2521L	possibly damaging	Het
Kif14	A	G	1: 136,443,724 (GRCm39)	D1299G	probably null	Het
Krt25	T	A	11: 99,208,253 (GRCm39)	E325V	probably damaging	Het
Lcmt1	T	C	7: 122,977,405 (GRCm39)		probably benign	Het
Lrp1b	A	T	2: 40,693,221 (GRCm39)	N3266K	probably damaging	Het
Mctp1	T	A	13: 77,168,982 (GRCm39)		probably null	Het
Mtarc2	A	G	1: 184,551,525 (GRCm39)	S304P	probably damaging	Het
Myo5b	G	A	18: 74,750,064 (GRCm39)	A176T	probably damaging	Het
Myom3	A	G	4: 135,503,688 (GRCm39)	N379S	possibly damaging	Het
Nbea	A	T	3: 55,908,037 (GRCm39)	D1358E	possibly damaging	Het
Nod1	T	C	6: 54,901,968 (GRCm39)	E939G	probably damaging	Het
Obox1	A	G	7: 15,289,294 (GRCm39)	R70G	probably benign	Het
Or13c25	A	G	4: 52,911,399 (GRCm39)	Y132H	probably damaging	Het
Or13p3	A	G	4: 118,567,144 (GRCm39)	E180G	probably benign	Het
Or4a2	C	T	2: 89,248,695 (GRCm39)	G21S	probably benign	Het
Or5m12	T	C	2: 85,734,560 (GRCm39)	I279M	probably benign	Het
Otof	T	C	5: 30,529,279 (GRCm39)	D1745G	possibly damaging	Het
Pklr	A	G	3: 89,044,662 (GRCm39)	I47V	probably damaging	Het
Pms2	T	A	5: 143,851,451 (GRCm39)	S123T	possibly damaging	Het
Pnpla2	T	C	7: 141,039,198 (GRCm39)	S337P	probably damaging	Het
Ptgfrn	A	C	3: 100,952,936 (GRCm39)	V766G	possibly damaging	Het
Ptpn11	T	A	5: 121,282,716 (GRCm39)	H419L	probably damaging	Het
Rims3	T	A	4: 120,740,350 (GRCm39)	V99E	probably damaging	Het
Rmc1	G	A	18: 12,313,571 (GRCm39)	R228H	probably damaging	Het
Samd9l	A	G	6: 3,376,361 (GRCm39)	V300A	probably damaging	Het
Sdad1	T	C	5: 92,451,789 (GRCm39)	D144G	probably damaging	Het
Siglecg	T	C	7: 43,058,178 (GRCm39)	Y22H	possibly damaging	Het
Slc39a1	A	G	3: 90,159,588 (GRCm39)	K305R	possibly damaging	Het
Slc5a4a	A	G	10: 76,014,034 (GRCm39)	R414G	probably damaging	Het
Smg1	T	C	7: 117,753,500 (GRCm39)		probably benign	Het
Tbc1d9b	C	T	11: 50,022,324 (GRCm39)	A20V	possibly damaging	Het
Tgfb3	G	T	12: 86,110,638 (GRCm39)	D237E	probably benign	Het
Tle6	A	G	10: 81,431,073 (GRCm39)	S234P	probably benign	Het
Tnrc6b	A	G	15: 80,763,815 (GRCm39)	N439S	probably benign	Het
Trim33	T	C	3: 103,248,925 (GRCm39)	S783P	probably benign	Het
Ttn	A	T	2: 76,632,698 (GRCm39)	Y12373N	probably damaging	Het
Tube1	G	A	10: 39,010,097 (GRCm39)	V7I	probably benign	Het
Tufm	T	C	7: 126,088,410 (GRCm39)	V265A	probably benign	Het
Usp32	T	C	11: 84,877,402 (GRCm39)	H1550R	possibly damaging	Het
Usp33	A	T	3: 152,081,887 (GRCm39)	M546L	probably damaging	Het
Uspl1	C	A	5: 149,151,097 (GRCm39)	Q752K	probably benign	Het
Vmn1r20	A	G	6: 57,408,655 (GRCm39)		probably null	Het
Vmn1r201	T	C	13: 22,659,521 (GRCm39)	F245S	probably damaging	Het
Vmn2r3	A	G	3: 64,186,182 (GRCm39)	S168P	probably damaging	Het
Wdr24	T	G	17: 26,044,650 (GRCm39)	D168E	possibly damaging	Het
Zfp646	C	T	7: 127,482,853 (GRCm39)	P1677S	probably damaging	Het

Other mutations in Ahnak

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00467:Ahnak	APN	19	8,984,587 (GRCm39)	missense	probably damaging	0.99
IGL00509:Ahnak	APN	19	8,987,315 (GRCm39)	missense	possibly damaging	0.94
IGL00539:Ahnak	APN	19	8,985,272 (GRCm39)	missense	possibly damaging	0.50
IGL00558:Ahnak	APN	19	8,981,671 (GRCm39)	missense	possibly damaging	0.93
IGL00567:Ahnak	APN	19	8,990,747 (GRCm39)	missense	probably benign	0.24
IGL00706:Ahnak	APN	19	8,991,094 (GRCm39)	nonsense	probably null
IGL00807:Ahnak	APN	19	8,985,886 (GRCm39)	missense	possibly damaging	0.92
IGL00870:Ahnak	APN	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
IGL01101:Ahnak	APN	19	8,990,251 (GRCm39)	intron	probably benign
IGL01118:Ahnak	APN	19	8,989,942 (GRCm39)	missense	probably damaging	1.00
IGL01288:Ahnak	APN	19	8,979,858 (GRCm39)	missense	possibly damaging	0.94
IGL01324:Ahnak	APN	19	8,980,396 (GRCm39)	missense	probably damaging	1.00
IGL01341:Ahnak	APN	19	8,989,067 (GRCm39)	missense	probably benign
IGL01541:Ahnak	APN	19	8,985,243 (GRCm39)	missense	possibly damaging	0.95
IGL01580:Ahnak	APN	19	8,980,203 (GRCm39)	missense	probably benign	0.02
IGL01595:Ahnak	APN	19	8,980,865 (GRCm39)	nonsense	probably null
IGL01746:Ahnak	APN	19	8,982,276 (GRCm39)	missense	possibly damaging	0.89
IGL01766:Ahnak	APN	19	8,977,482 (GRCm39)	missense	unknown
IGL01821:Ahnak	APN	19	8,989,482 (GRCm39)	missense	probably benign
IGL01913:Ahnak	APN	19	8,983,428 (GRCm39)	nonsense	probably null
IGL01934:Ahnak	APN	19	8,980,021 (GRCm39)	missense	probably damaging	1.00
IGL01940:Ahnak	APN	19	8,983,921 (GRCm39)	missense	probably benign	0.14
IGL01958:Ahnak	APN	19	8,992,273 (GRCm39)	missense	possibly damaging	0.59
IGL02145:Ahnak	APN	19	8,980,219 (GRCm39)	missense	probably benign	0.11
IGL02246:Ahnak	APN	19	8,985,632 (GRCm39)	missense	probably damaging	1.00
IGL02282:Ahnak	APN	19	8,983,351 (GRCm39)	missense	probably damaging	1.00
IGL02428:Ahnak	APN	19	8,992,197 (GRCm39)	missense	possibly damaging	0.83
IGL02442:Ahnak	APN	19	8,981,380 (GRCm39)	missense	probably damaging	1.00
IGL02474:Ahnak	APN	19	8,982,297 (GRCm39)	missense	probably benign	0.13
IGL02483:Ahnak	APN	19	8,980,672 (GRCm39)	missense	probably benign	0.01
IGL02616:Ahnak	APN	19	8,982,991 (GRCm39)	missense	probably benign	0.03
IGL02630:Ahnak	APN	19	8,989,441 (GRCm39)	missense	probably damaging	1.00
IGL02690:Ahnak	APN	19	8,989,948 (GRCm39)	nonsense	probably null
IGL02717:Ahnak	APN	19	8,979,751 (GRCm39)	missense	probably benign	0.00
IGL02721:Ahnak	APN	19	8,987,071 (GRCm39)	missense	probably benign	0.07
IGL02737:Ahnak	APN	19	8,981,957 (GRCm39)	missense	probably benign	0.17
IGL02850:Ahnak	APN	19	8,979,960 (GRCm39)	missense	probably benign	0.00
IGL03071:Ahnak	APN	19	8,989,282 (GRCm39)	missense	possibly damaging	0.63
IGL03072:Ahnak	APN	19	8,983,872 (GRCm39)	missense	probably benign	0.11
IGL03094:Ahnak	APN	19	8,980,911 (GRCm39)	missense	possibly damaging	0.64
IGL03140:Ahnak	APN	19	8,982,576 (GRCm39)	intron	probably benign
IGL03176:Ahnak	APN	19	8,979,813 (GRCm39)	missense	probably damaging	1.00
IGL03176:Ahnak	APN	19	8,985,530 (GRCm39)	missense	possibly damaging	0.56
IGL03189:Ahnak	APN	19	8,988,603 (GRCm39)	missense	possibly damaging	0.65
IGL03357:Ahnak	APN	19	8,986,689 (GRCm39)	intron	probably benign
IGL03371:Ahnak	APN	19	8,981,592 (GRCm39)	missense	possibly damaging	0.91
Eskimo	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
Nanook	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
Netsilik	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
IGL03097:Ahnak	UTSW	19	8,979,751 (GRCm39)	missense	probably benign	0.00
PIT4403001:Ahnak	UTSW	19	8,983,540 (GRCm39)	missense	possibly damaging	0.87
R0054:Ahnak	UTSW	19	8,989,420 (GRCm39)	missense	probably damaging	1.00
R0094:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R0110:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0141:Ahnak	UTSW	19	8,984,044 (GRCm39)	missense	probably damaging	1.00
R0166:Ahnak	UTSW	19	8,983,089 (GRCm39)	missense	probably damaging	1.00
R0309:Ahnak	UTSW	19	8,979,859 (GRCm39)	missense	probably damaging	1.00
R0368:Ahnak	UTSW	19	8,985,714 (GRCm39)	nonsense	probably null
R0386:Ahnak	UTSW	19	8,988,508 (GRCm39)	missense	possibly damaging	0.94
R0401:Ahnak	UTSW	19	8,992,480 (GRCm39)	missense	probably benign	0.24
R0415:Ahnak	UTSW	19	8,990,235 (GRCm39)	intron	probably benign
R0463:Ahnak	UTSW	19	8,986,771 (GRCm39)	intron	probably benign
R0469:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0470:Ahnak	UTSW	19	8,986,331 (GRCm39)	missense	probably benign	0.29
R0487:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R0487:Ahnak	UTSW	19	8,984,515 (GRCm39)	missense	probably benign	0.00
R0499:Ahnak	UTSW	19	8,977,628 (GRCm39)	splice site	probably benign
R0506:Ahnak	UTSW	19	8,986,492 (GRCm39)	missense	probably damaging	1.00
R0510:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0557:Ahnak	UTSW	19	8,979,308 (GRCm39)	missense	probably benign	0.10
R0570:Ahnak	UTSW	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
R0610:Ahnak	UTSW	19	8,985,242 (GRCm39)	missense	probably benign	0.08
R0646:Ahnak	UTSW	19	8,990,766 (GRCm39)	nonsense	probably null
R0659:Ahnak	UTSW	19	8,992,366 (GRCm39)	missense	possibly damaging	0.60
R0791:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0792:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0840:Ahnak	UTSW	19	8,982,427 (GRCm39)	missense	probably damaging	1.00
R0847:Ahnak	UTSW	19	8,983,797 (GRCm39)	nonsense	probably null
R0941:Ahnak	UTSW	19	8,987,278 (GRCm39)	missense	probably damaging	1.00
R0962:Ahnak	UTSW	19	8,990,212 (GRCm39)	intron	probably benign
R1017:Ahnak	UTSW	19	8,987,907 (GRCm39)	missense	probably damaging	0.99
R1037:Ahnak	UTSW	19	8,984,982 (GRCm39)	missense	probably benign	0.27
R1085:Ahnak	UTSW	19	8,990,489 (GRCm39)	missense	possibly damaging	0.50
R1113:Ahnak	UTSW	19	8,982,984 (GRCm39)	missense	probably benign	0.29
R1140:Ahnak	UTSW	19	8,981,609 (GRCm39)	missense	probably damaging	1.00
R1158:Ahnak	UTSW	19	8,991,290 (GRCm39)	missense	probably benign	0.00
R1218:Ahnak	UTSW	19	8,992,983 (GRCm39)	missense	probably damaging	1.00
R1225:Ahnak	UTSW	19	8,980,247 (GRCm39)	missense	probably damaging	1.00
R1245:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R1421:Ahnak	UTSW	19	8,992,995 (GRCm39)	missense	possibly damaging	0.95
R1447:Ahnak	UTSW	19	8,984,446 (GRCm39)	missense	probably damaging	0.98
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1471:Ahnak	UTSW	19	8,990,296 (GRCm39)	intron	probably benign
R1507:Ahnak	UTSW	19	8,987,441 (GRCm39)	missense	probably damaging	1.00
R1521:Ahnak	UTSW	19	8,982,092 (GRCm39)	missense	probably benign	0.11
R1568:Ahnak	UTSW	19	8,979,739 (GRCm39)	missense	probably damaging	0.98
R1569:Ahnak	UTSW	19	8,981,458 (GRCm39)	missense	possibly damaging	0.78
R1616:Ahnak	UTSW	19	8,986,351 (GRCm39)	missense	possibly damaging	0.94
R1638:Ahnak	UTSW	19	8,986,813 (GRCm39)	missense	probably benign	0.01
R1680:Ahnak	UTSW	19	8,987,327 (GRCm39)	missense	probably benign	0.05
R1713:Ahnak	UTSW	19	8,989,173 (GRCm39)	missense	possibly damaging	0.95
R1722:Ahnak	UTSW	19	8,988,019 (GRCm39)	missense	probably damaging	0.99
R1771:Ahnak	UTSW	19	8,991,117 (GRCm39)	missense	probably benign	0.24
R1795:Ahnak	UTSW	19	8,979,802 (GRCm39)	missense	possibly damaging	0.79
R1823:Ahnak	UTSW	19	8,982,269 (GRCm39)	missense	probably damaging	0.99
R1842:Ahnak	UTSW	19	8,983,231 (GRCm39)	missense	probably damaging	0.99
R1854:Ahnak	UTSW	19	8,991,196 (GRCm39)	missense	possibly damaging	0.61
R1856:Ahnak	UTSW	19	8,979,412 (GRCm39)	missense	possibly damaging	0.86
R1886:Ahnak	UTSW	19	8,993,343 (GRCm39)	missense	probably damaging	0.98
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1912:Ahnak	UTSW	19	8,995,245 (GRCm39)	missense	probably damaging	1.00
R1913:Ahnak	UTSW	19	8,985,286 (GRCm39)	missense	probably damaging	0.99
R1942:Ahnak	UTSW	19	8,992,447 (GRCm39)	missense	probably damaging	0.98
R1987:Ahnak	UTSW	19	8,992,615 (GRCm39)	missense	probably damaging	1.00
R2006:Ahnak	UTSW	19	8,984,439 (GRCm39)	missense	probably damaging	1.00
R2013:Ahnak	UTSW	19	8,991,937 (GRCm39)	missense	probably damaging	0.98
R2014:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R2047:Ahnak	UTSW	19	8,991,664 (GRCm39)	missense	possibly damaging	0.67
R2048:Ahnak	UTSW	19	8,984,420 (GRCm39)	missense	probably damaging	0.99
R2060:Ahnak	UTSW	19	8,985,405 (GRCm39)	missense	probably benign	0.08
R2083:Ahnak	UTSW	19	8,988,921 (GRCm39)	missense	probably damaging	1.00
R2157:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R2167:Ahnak	UTSW	19	8,988,858 (GRCm39)	nonsense	probably null
R2208:Ahnak	UTSW	19	8,995,096 (GRCm39)	missense	probably benign	0.00
R2224:Ahnak	UTSW	19	8,990,355 (GRCm39)	intron	probably benign
R2268:Ahnak	UTSW	19	8,987,938 (GRCm39)	missense	possibly damaging	0.66
R2420:Ahnak	UTSW	19	8,986,620 (GRCm39)	missense	possibly damaging	0.89
R2426:Ahnak	UTSW	19	8,980,215 (GRCm39)	missense	possibly damaging	0.81
R2910:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2911:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2981:Ahnak	UTSW	19	8,977,512 (GRCm39)	missense	probably damaging	0.97
R3151:Ahnak	UTSW	19	8,987,308 (GRCm39)	missense	probably benign	0.12
R3155:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R3422:Ahnak	UTSW	19	8,984,116 (GRCm39)	missense	probably benign	0.05
R3422:Ahnak	UTSW	19	8,983,072 (GRCm39)	missense	probably benign	0.39
R3430:Ahnak	UTSW	19	8,984,322 (GRCm39)	missense	probably benign	0.42
R3433:Ahnak	UTSW	19	8,987,358 (GRCm39)	missense	probably benign	0.01
R3711:Ahnak	UTSW	19	8,985,262 (GRCm39)	missense	probably benign
R3723:Ahnak	UTSW	19	8,994,217 (GRCm39)	missense	possibly damaging	0.79
R3775:Ahnak	UTSW	19	8,986,387 (GRCm39)	missense	possibly damaging	0.91
R3858:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3859:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3922:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3924:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3926:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R4026:Ahnak	UTSW	19	8,988,663 (GRCm39)	missense	probably damaging	0.97
R4051:Ahnak	UTSW	19	8,991,691 (GRCm39)	missense	probably damaging	1.00
R4209:Ahnak	UTSW	19	8,979,964 (GRCm39)	missense	probably damaging	1.00
R4234:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R4237:Ahnak	UTSW	19	8,979,147 (GRCm39)	missense	probably benign	0.02
R4285:Ahnak	UTSW	19	8,994,203 (GRCm39)	nonsense	probably null
R4331:Ahnak	UTSW	19	8,993,184 (GRCm39)	missense	probably damaging	1.00
R4342:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R4430:Ahnak	UTSW	19	8,980,404 (GRCm39)	missense	probably benign	0.00
R4554:Ahnak	UTSW	19	8,992,294 (GRCm39)	missense	probably damaging	1.00
R4602:Ahnak	UTSW	19	8,988,189 (GRCm39)	missense	possibly damaging	0.66
R4612:Ahnak	UTSW	19	8,981,088 (GRCm39)	missense	probably benign	0.44
R4655:Ahnak	UTSW	19	8,986,065 (GRCm39)	missense	probably damaging	1.00
R4656:Ahnak	UTSW	19	8,982,219 (GRCm39)	missense	possibly damaging	0.80
R4700:Ahnak	UTSW	19	8,982,045 (GRCm39)	missense	probably benign	0.02
R4704:Ahnak	UTSW	19	8,989,622 (GRCm39)	intron	probably benign
R4704:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R4705:Ahnak	UTSW	19	8,994,270 (GRCm39)	missense	probably benign	0.07
R4707:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	probably benign	0.03
R4732:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4733:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4778:Ahnak	UTSW	19	8,989,339 (GRCm39)	missense	possibly damaging	0.79
R4782:Ahnak	UTSW	19	8,989,863 (GRCm39)	intron	probably benign
R4832:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R4882:Ahnak	UTSW	19	8,983,261 (GRCm39)	missense	probably damaging	0.98
R4884:Ahnak	UTSW	19	8,990,118 (GRCm39)	intron	probably benign
R4895:Ahnak	UTSW	19	8,994,805 (GRCm39)	missense	probably benign	0.43
R4930:Ahnak	UTSW	19	8,988,331 (GRCm39)	missense	possibly damaging	0.79
R4951:Ahnak	UTSW	19	8,995,199 (GRCm39)	missense	probably damaging	1.00
R4968:Ahnak	UTSW	19	8,992,464 (GRCm39)	missense	probably damaging	1.00
R5026:Ahnak	UTSW	19	8,987,995 (GRCm39)	missense	possibly damaging	0.46
R5050:Ahnak	UTSW	19	8,989,822 (GRCm39)	intron	probably benign
R5073:Ahnak	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
R5110:Ahnak	UTSW	19	8,992,123 (GRCm39)	missense	probably damaging	1.00
R5119:Ahnak	UTSW	19	8,991,008 (GRCm39)	missense	probably benign	0.00
R5128:Ahnak	UTSW	19	8,994,451 (GRCm39)	missense	probably damaging	1.00
R5139:Ahnak	UTSW	19	8,982,019 (GRCm39)	missense	probably damaging	1.00
R5150:Ahnak	UTSW	19	8,988,268 (GRCm39)	missense	possibly damaging	0.46
R5151:Ahnak	UTSW	19	8,994,933 (GRCm39)	missense	probably benign	0.03
R5165:Ahnak	UTSW	19	8,993,029 (GRCm39)	missense	possibly damaging	0.95
R5236:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R5361:Ahnak	UTSW	19	8,992,705 (GRCm39)	missense	possibly damaging	0.92
R5366:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	possibly damaging	0.65
R5387:Ahnak	UTSW	19	8,981,055 (GRCm39)	missense	probably damaging	1.00
R5396:Ahnak	UTSW	19	8,984,539 (GRCm39)	missense	probably damaging	0.99
R5583:Ahnak	UTSW	19	8,984,281 (GRCm39)	missense	probably damaging	0.99
R5587:Ahnak	UTSW	19	8,986,840 (GRCm39)	missense	possibly damaging	0.88
R5620:Ahnak	UTSW	19	8,990,458 (GRCm39)	nonsense	probably null
R5643:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5644:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5657:Ahnak	UTSW	19	8,991,979 (GRCm39)	missense	probably damaging	0.99
R5688:Ahnak	UTSW	19	8,979,883 (GRCm39)	missense	probably benign	0.01
R5702:Ahnak	UTSW	19	8,979,204 (GRCm39)	missense	probably damaging	1.00
R5727:Ahnak	UTSW	19	8,994,111 (GRCm39)	missense	probably damaging	0.99
R5730:Ahnak	UTSW	19	8,987,617 (GRCm39)	missense	possibly damaging	0.81
R5755:Ahnak	UTSW	19	8,979,096 (GRCm39)	missense	probably benign	0.06
R5760:Ahnak	UTSW	19	8,990,926 (GRCm39)	missense	probably damaging	1.00
R5789:Ahnak	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
R5790:Ahnak	UTSW	19	8,992,612 (GRCm39)	missense	probably damaging	0.99
R5795:Ahnak	UTSW	19	8,989,746 (GRCm39)	nonsense	probably null
R5808:Ahnak	UTSW	19	8,987,599 (GRCm39)	missense	possibly damaging	0.91
R5867:Ahnak	UTSW	19	8,987,416 (GRCm39)	missense	probably damaging	0.99
R5878:Ahnak	UTSW	19	8,985,706 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,995,575 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,991,131 (GRCm39)	missense	possibly damaging	0.63
R5912:Ahnak	UTSW	19	8,989,267 (GRCm39)	missense	probably damaging	0.99
R5935:Ahnak	UTSW	19	8,992,546 (GRCm39)	missense	possibly damaging	0.91
R5969:Ahnak	UTSW	19	8,993,949 (GRCm39)	missense	probably damaging	1.00
R5988:Ahnak	UTSW	19	8,986,711 (GRCm39)	intron	probably benign
R6000:Ahnak	UTSW	19	8,990,475 (GRCm39)	nonsense	probably null
R6005:Ahnak	UTSW	19	8,992,525 (GRCm39)	missense	possibly damaging	0.61
R6101:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6105:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6116:Ahnak	UTSW	19	8,990,327 (GRCm39)	intron	probably benign
R6209:Ahnak	UTSW	19	8,989,930 (GRCm39)	missense	probably damaging	1.00
R6240:Ahnak	UTSW	19	8,990,947 (GRCm39)	missense	probably damaging	1.00
R6255:Ahnak	UTSW	19	8,985,389 (GRCm39)	missense	possibly damaging	0.95
R6263:Ahnak	UTSW	19	8,995,641 (GRCm39)	missense	probably benign	0.03
R6287:Ahnak	UTSW	19	8,992,367 (GRCm39)	missense	probably benign	0.02
R6296:Ahnak	UTSW	19	8,980,669 (GRCm39)	missense	probably damaging	0.99
R6315:Ahnak	UTSW	19	8,983,990 (GRCm39)	missense	probably damaging	0.99
R6328:Ahnak	UTSW	19	8,984,512 (GRCm39)	missense	probably benign	0.11
R6355:Ahnak	UTSW	19	8,986,126 (GRCm39)	missense	probably benign	0.02
R6409:Ahnak	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
R6567:Ahnak	UTSW	19	8,986,170 (GRCm39)	missense	probably benign	0.27
R6572:Ahnak	UTSW	19	8,985,340 (GRCm39)	missense	probably damaging	0.99
R6574:Ahnak	UTSW	19	8,994,411 (GRCm39)	missense	probably benign	0.04
R6590:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6620:Ahnak	UTSW	19	8,992,674 (GRCm39)	missense	possibly damaging	0.95
R6690:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6731:Ahnak	UTSW	19	8,988,926 (GRCm39)	missense	possibly damaging	0.85
R6756:Ahnak	UTSW	19	8,984,925 (GRCm39)	missense	possibly damaging	0.59
R6846:Ahnak	UTSW	19	8,989,221 (GRCm39)	missense	possibly damaging	0.66
R6854:Ahnak	UTSW	19	8,992,599 (GRCm39)	missense	probably damaging	1.00
R6857:Ahnak	UTSW	19	9,014,532 (GRCm39)	nonsense	probably null
R6863:Ahnak	UTSW	19	8,989,729 (GRCm39)	intron	probably benign
R6876:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R6958:Ahnak	UTSW	19	8,992,579 (GRCm39)	missense	possibly damaging	0.88
R7126:Ahnak	UTSW	19	8,979,723 (GRCm39)	missense	possibly damaging	0.61
R7181:Ahnak	UTSW	19	8,990,852 (GRCm39)	missense	probably damaging	1.00
R7183:Ahnak	UTSW	19	8,995,032 (GRCm39)	missense	probably damaging	1.00
R7202:Ahnak	UTSW	19	8,995,163 (GRCm39)	missense	probably damaging	1.00
R7235:Ahnak	UTSW	19	8,989,852 (GRCm39)	missense	unknown
R7241:Ahnak	UTSW	19	8,986,395 (GRCm39)	missense	possibly damaging	0.65
R7269:Ahnak	UTSW	19	8,983,981 (GRCm39)	missense	probably damaging	1.00
R7311:Ahnak	UTSW	19	8,979,507 (GRCm39)	missense	probably benign	0.04
R7311:Ahnak	UTSW	19	8,987,191 (GRCm39)	missense	possibly damaging	0.56
R7329:Ahnak	UTSW	19	8,979,156 (GRCm39)	missense	probably damaging	0.99
R7339:Ahnak	UTSW	19	8,985,529 (GRCm39)	missense	possibly damaging	0.75
R7390:Ahnak	UTSW	19	8,980,569 (GRCm39)	missense	probably benign	0.02
R7400:Ahnak	UTSW	19	8,991,977 (GRCm39)	missense	probably damaging	0.99
R7444:Ahnak	UTSW	19	8,984,787 (GRCm39)	missense	probably benign	0.08
R7483:Ahnak	UTSW	19	8,982,186 (GRCm39)	missense	probably damaging	1.00
R7498:Ahnak	UTSW	19	8,989,383 (GRCm39)	missense	probably benign	0.14
R7521:Ahnak	UTSW	19	8,979,715 (GRCm39)	missense	possibly damaging	0.89
R7522:Ahnak	UTSW	19	8,979,686 (GRCm39)	missense	probably benign	0.01
R7552:Ahnak	UTSW	19	8,984,188 (GRCm39)	missense	probably benign	0.18
R7563:Ahnak	UTSW	19	8,988,529 (GRCm39)	missense	probably damaging	0.99
R7565:Ahnak	UTSW	19	8,993,520 (GRCm39)	missense	probably benign	0.05
R7571:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R7583:Ahnak	UTSW	19	8,983,457 (GRCm39)	missense	possibly damaging	0.90
R7600:Ahnak	UTSW	19	8,981,938 (GRCm39)	missense	possibly damaging	0.89
R7771:Ahnak	UTSW	19	8,992,411 (GRCm39)	missense	probably damaging	0.99
R7787:Ahnak	UTSW	19	8,986,679 (GRCm39)	missense	unknown
R7827:Ahnak	UTSW	19	8,982,708 (GRCm39)	nonsense	probably null
R7857:Ahnak	UTSW	19	8,984,832 (GRCm39)	missense	probably damaging	0.97
R7916:Ahnak	UTSW	19	8,983,196 (GRCm39)	missense	possibly damaging	0.66
R7939:Ahnak	UTSW	19	8,991,448 (GRCm39)	nonsense	probably null
R7959:Ahnak	UTSW	19	8,988,013 (GRCm39)	missense	possibly damaging	0.46
R7962:Ahnak	UTSW	19	8,990,164 (GRCm39)	missense	unknown
R7979:Ahnak	UTSW	19	8,988,796 (GRCm39)	missense	probably damaging	1.00
R8006:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R8013:Ahnak	UTSW	19	8,986,699 (GRCm39)	missense	unknown
R8033:Ahnak	UTSW	19	8,981,074 (GRCm39)	missense	probably benign	0.10
R8124:Ahnak	UTSW	19	8,984,487 (GRCm39)	missense	probably damaging	0.99
R8125:Ahnak	UTSW	19	8,989,240 (GRCm39)	missense	possibly damaging	0.95
R8129:Ahnak	UTSW	19	8,977,464 (GRCm39)	start codon destroyed	not run
R8151:Ahnak	UTSW	19	8,982,043 (GRCm39)	missense	possibly damaging	0.59
R8190:Ahnak	UTSW	19	8,979,619 (GRCm39)	missense	probably benign	0.01
R8221:Ahnak	UTSW	19	8,987,800 (GRCm39)	nonsense	probably null
R8241:Ahnak	UTSW	19	8,984,659 (GRCm39)	missense	probably benign	0.15
R8244:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8248:Ahnak	UTSW	19	8,979,310 (GRCm39)	missense	probably damaging	1.00
R8261:Ahnak	UTSW	19	8,982,817 (GRCm39)	missense	probably damaging	1.00
R8330:Ahnak	UTSW	19	8,987,026 (GRCm39)	missense	possibly damaging	0.86
R8380:Ahnak	UTSW	19	8,995,219 (GRCm39)	missense	probably benign	0.05
R8407:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8409:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8463:Ahnak	UTSW	19	8,986,113 (GRCm39)	missense	probably benign	0.07
R8511:Ahnak	UTSW	19	8,989,719 (GRCm39)	missense	unknown
R8528:Ahnak	UTSW	19	8,985,092 (GRCm39)	missense	probably damaging	1.00
R8549:Ahnak	UTSW	19	8,988,847 (GRCm39)	missense	probably damaging	1.00
R8674:Ahnak	UTSW	19	8,983,360 (GRCm39)	missense	probably damaging	0.98
R8716:Ahnak	UTSW	19	8,986,438 (GRCm39)	missense	probably damaging	1.00
R8722:Ahnak	UTSW	19	8,990,710 (GRCm39)	nonsense	probably null
R8751:Ahnak	UTSW	19	8,987,509 (GRCm39)	missense	probably damaging	1.00
R8752:Ahnak	UTSW	19	8,992,901 (GRCm39)	missense	probably damaging	1.00
R8783:Ahnak	UTSW	19	8,988,837 (GRCm39)	missense	probably damaging	1.00
R8844:Ahnak	UTSW	19	8,984,254 (GRCm39)	missense	probably damaging	1.00
R8859:Ahnak	UTSW	19	8,984,567 (GRCm39)	missense	probably damaging	1.00
R8882:Ahnak	UTSW	19	8,978,106 (GRCm39)	missense	probably damaging	1.00
R8907:Ahnak	UTSW	19	8,986,452 (GRCm39)	missense	probably benign	0.24
R8938:Ahnak	UTSW	19	8,989,099 (GRCm39)	missense	probably benign	0.00
R8975:Ahnak	UTSW	19	8,990,101 (GRCm39)	missense	probably damaging	1.00
R8983:Ahnak	UTSW	19	8,981,477 (GRCm39)	missense	possibly damaging	0.75
R9017:Ahnak	UTSW	19	8,987,487 (GRCm39)	missense	probably damaging	1.00
R9027:Ahnak	UTSW	19	8,984,617 (GRCm39)	missense	possibly damaging	0.94
R9081:Ahnak	UTSW	19	8,985,890 (GRCm39)	missense	possibly damaging	0.81
R9104:Ahnak	UTSW	19	8,987,711 (GRCm39)	missense	probably benign	0.01
R9112:Ahnak	UTSW	19	8,987,149 (GRCm39)	missense	probably damaging	0.98
R9145:Ahnak	UTSW	19	8,992,287 (GRCm39)	missense	probably benign	0.38
R9189:Ahnak	UTSW	19	8,988,247 (GRCm39)	missense	possibly damaging	0.92
R9221:Ahnak	UTSW	19	8,989,943 (GRCm39)	missense	probably damaging	1.00
R9261:Ahnak	UTSW	19	8,993,503 (GRCm39)	missense	possibly damaging	0.63
R9299:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9325:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R9337:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9340:Ahnak	UTSW	19	8,994,411 (GRCm39)	missense	probably benign	0.04
R9351:Ahnak	UTSW	19	8,985,232 (GRCm39)	missense	probably damaging	1.00
R9416:Ahnak	UTSW	19	8,990,266 (GRCm39)	missense	unknown
R9462:Ahnak	UTSW	19	8,981,299 (GRCm39)	missense	probably damaging	0.96
R9469:Ahnak	UTSW	19	8,988,225 (GRCm39)	missense	probably damaging	1.00
R9485:Ahnak	UTSW	19	8,979,438 (GRCm39)	missense	probably benign	0.16
R9503:Ahnak	UTSW	19	8,987,458 (GRCm39)	missense	probably damaging	1.00
R9524:Ahnak	UTSW	19	9,014,617 (GRCm39)	missense
R9534:Ahnak	UTSW	19	8,980,976 (GRCm39)	missense	probably benign	0.20
R9598:Ahnak	UTSW	19	8,981,149 (GRCm39)	missense	probably benign	0.42
R9611:Ahnak	UTSW	19	8,989,162 (GRCm39)	missense	probably damaging	0.99
R9624:Ahnak	UTSW	19	8,989,846 (GRCm39)	missense	unknown
R9649:Ahnak	UTSW	19	8,985,786 (GRCm39)	nonsense	probably null
R9683:Ahnak	UTSW	19	8,984,719 (GRCm39)	missense	possibly damaging	0.94
R9691:Ahnak	UTSW	19	8,989,090 (GRCm39)	missense	possibly damaging	0.49
R9712:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9712:Ahnak	UTSW	19	8,984,392 (GRCm39)	small deletion	probably benign
R9713:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9715:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9725:Ahnak	UTSW	19	8,991,607 (GRCm39)	missense	probably damaging	1.00
R9725:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R9747:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R9798:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
RF007:Ahnak	UTSW	19	8,990,965 (GRCm39)	missense	possibly damaging	0.45
X0021:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
X0027:Ahnak	UTSW	19	8,989,401 (GRCm39)	missense	probably damaging	1.00
Z1088:Ahnak	UTSW	19	8,993,446 (GRCm39)	missense	probably damaging	0.99
Z1176:Ahnak	UTSW	19	8,986,220 (GRCm39)	missense	probably damaging	0.97
Z1177:Ahnak	UTSW	19	8,994,832 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AGGGTCCCAAGTTCAAGATGC -3'
(R):5'- ACATCTACATCTGGGGCATTG -3'

Sequencing Primer
(F):5'- CAAAATCTCTATGCCTGATGTTGGG -3'
(R):5'- ACATCTACATCTGGGGCATTGATGTC -3'

Posted On

2018-04-02