Incidental Mutation 'FR4342:Cluh'
| ID |
511274 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cluh
|
| Ensembl Gene |
ENSMUSG00000020741 |
| Gene Name |
clustered mitochondria homolog |
| Synonyms |
1300001I01Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.205)
|
| Stock # |
FR4342 ()
|
| Quality Score |
217.468 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
74540321-74561673 bp(+) (GRCm39) |
| Type of Mutation |
small insertion (2 aa in frame mutation) |
| DNA Base Change (assembly) |
GCCTGA to GCCTGAACCTGA
at 74560352 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113371
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000021091]
[ENSMUST00000092915]
[ENSMUST00000102520]
[ENSMUST00000117818]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000021091
|
| SMART Domains |
Protein: ENSMUSP00000021091
Gene: ENSMUSG00000020745
| Domain | Start | End | E-Value | Type |
|---|
|
LisH
|
7 |
39 |
6.12e-7 |
SMART |
|
WD40
|
97 |
136 |
2.1e-7 |
SMART |
|
WD40
|
139 |
178 |
9.73e-12 |
SMART |
|
WD40
|
181 |
220 |
1.1e-10 |
SMART |
|
WD40
|
223 |
262 |
9.3e-9 |
SMART |
|
WD40
|
265 |
324 |
4.65e-9 |
SMART |
|
WD40
|
327 |
366 |
4.11e-10 |
SMART |
|
WD40
|
369 |
408 |
8.81e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092915
|
| SMART Domains |
Protein: ENSMUSP00000090593
Gene: ENSMUSG00000020741
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:CLU_N
|
104 |
177 |
3.1e-28 |
PFAM |
|
Pfam:CLU
|
394 |
614 |
3.4e-89 |
PFAM |
|
Pfam:eIF3_p135
|
806 |
988 |
1.3e-58 |
PFAM |
|
Pfam:TPR_10
|
1059 |
1100 |
2.9e-7 |
PFAM |
|
low complexity region
|
1114 |
1125 |
N/A |
INTRINSIC |
|
Pfam:TPR_12
|
1140 |
1218 |
1.7e-10 |
PFAM |
|
low complexity region
|
1316 |
1334 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102520
|
| SMART Domains |
Protein: ENSMUSP00000099578
Gene: ENSMUSG00000020745
| Domain | Start | End | E-Value | Type |
|---|
|
LisH
|
7 |
39 |
6.12e-7 |
SMART |
|
WD40
|
97 |
136 |
2.1e-7 |
SMART |
|
WD40
|
139 |
178 |
9.73e-12 |
SMART |
|
WD40
|
181 |
220 |
1.1e-10 |
SMART |
|
WD40
|
223 |
262 |
9.3e-9 |
SMART |
|
WD40
|
265 |
324 |
4.65e-9 |
SMART |
|
WD40
|
327 |
366 |
4.11e-10 |
SMART |
|
WD40
|
369 |
408 |
8.81e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117818
|
| SMART Domains |
Protein: ENSMUSP00000113371
Gene: ENSMUSG00000020741
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:CLU_N
|
102 |
177 |
9.8e-30 |
PFAM |
|
Pfam:CLU
|
394 |
615 |
5.3e-92 |
PFAM |
|
Pfam:eIF3_p135
|
796 |
938 |
2.9e-38 |
PFAM |
|
Pfam:TPR_10
|
1008 |
1049 |
9.5e-7 |
PFAM |
|
low complexity region
|
1063 |
1074 |
N/A |
INTRINSIC |
|
Pfam:TPR_12
|
1089 |
1167 |
1.1e-9 |
PFAM |
|
low complexity region
|
1265 |
1283 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126341
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128155
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155558
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156794
|
| Coding Region Coverage |
- 1x: 99.7%
- 3x: 99.4%
- 10x: 97.8%
- 20x: 93.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Constitutive homozygous KO affects liver mitochondrial function and leads to neonatal lethality. Conditional homozygous KO in the adult liver affects cellular respiration under energy stress conditions. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 107 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810004N23Rik |
TT |
TTATGT |
8: 125,566,572 (GRCm39) |
|
probably null |
Homo |
| 4930433I11Rik |
AACC |
A |
7: 40,642,479 (GRCm39) |
|
probably benign |
Het |
| 7530416G11Rik |
T |
A |
15: 85,378,508 (GRCm39) |
E45V |
unknown |
Homo |
| Ankrd35 |
TCCCC |
TCCC |
3: 96,590,831 (GRCm39) |
|
probably null |
Het |
| Anxa2 |
CCC |
CCCACC |
9: 69,387,487 (GRCm39) |
|
probably benign |
Het |
| Anxa2 |
C |
CCCA |
9: 69,387,492 (GRCm39) |
|
probably benign |
Het |
| Apc |
CAATAAAGC |
CAATAAAGCAAATAAAGC |
18: 34,415,052 (GRCm39) |
|
probably benign |
Homo |
| Arrb2 |
C |
T |
11: 70,329,497 (GRCm39) |
T269M |
probably damaging |
Homo |
| Bcas3 |
G |
A |
11: 85,400,323 (GRCm39) |
V431I |
probably benign |
Homo |
| Begain |
CCCCGCC |
CCCCGCCCCCGCC |
12: 108,999,344 (GRCm39) |
|
probably benign |
Homo |
| Catsper2 |
TCA |
TCAACA |
2: 121,228,274 (GRCm39) |
|
probably benign |
Het |
| Ccdc121 |
GAGAAG |
GAG |
5: 31,644,717 (GRCm39) |
|
probably benign |
Homo |
| Cd164 |
G |
T |
10: 41,397,922 (GRCm39) |
A59S |
probably benign |
Homo |
| Cd22 |
C |
T |
7: 30,577,507 (GRCm39) |
R2H |
possibly damaging |
Homo |
| Cimip2b |
CAGAG |
CAG |
4: 43,427,384 (GRCm39) |
|
probably null |
Homo |
| Cntnap1 |
AGCCCC |
AGCCCCCGCCCC |
11: 101,080,401 (GRCm39) |
|
probably benign |
Het |
| Col2a1 |
C |
A |
15: 97,886,862 (GRCm39) |
|
probably null |
Het |
| Col6a5 |
A |
T |
9: 105,811,373 (GRCm39) |
N715K |
unknown |
Homo |
| Cpeb4 |
T |
TGA |
11: 31,877,638 (GRCm39) |
|
probably benign |
Homo |
| Dbr1 |
AGGAGG |
AGGAGGGGGAGG |
9: 99,465,733 (GRCm39) |
|
probably benign |
Het |
| Defa29 |
C |
G |
8: 21,816,160 (GRCm39) |
R69P |
probably benign |
Het |
| Dhx8 |
CG |
CGAGAACGG |
11: 101,629,032 (GRCm39) |
|
probably null |
Het |
| Dnaaf9 |
TCC |
TCCCCC |
2: 130,612,662 (GRCm39) |
|
probably benign |
Het |
| Dnah12 |
G |
T |
14: 26,571,342 (GRCm39) |
G2817V |
probably damaging |
Homo |
| Dthd1 |
C |
CTTA |
5: 63,000,369 (GRCm39) |
|
probably benign |
Homo |
| E4f1 |
GC |
GCCCC |
17: 24,674,171 (GRCm39) |
|
probably benign |
Het |
| F830016B08Rik |
A |
ACAG |
18: 60,433,013 (GRCm39) |
|
probably benign |
Homo |
| Fbrsl1 |
GTGTGTGTGCTGGTGCGTGTGCTGGTG |
GTGTGTGTGCTGGTGTGTGTGCTGGTGCGTGTGCTGGTG |
5: 110,525,991 (GRCm39) |
|
probably benign |
Het |
| Fbxo22 |
A |
C |
9: 55,128,354 (GRCm39) |
|
probably null |
Het |
| Flg |
G |
A |
3: 93,197,820 (GRCm39) |
|
probably benign |
Het |
| Fmn1 |
TCC |
TCCTCCACC |
2: 113,356,128 (GRCm39) |
|
probably benign |
Homo |
| Frmpd2 |
G |
T |
14: 33,232,978 (GRCm39) |
L399F |
probably damaging |
Homo |
| Gbp2b |
A |
G |
3: 142,309,413 (GRCm39) |
I175V |
probably benign |
Het |
| Gjc2 |
T |
TCCCG |
11: 59,073,569 (GRCm39) |
|
probably benign |
Homo |
| Gm14496 |
A |
C |
2: 181,637,699 (GRCm39) |
K258Q |
probably benign |
Het |
| Gm4340 |
CAGAAG |
CAGAAGAAG |
10: 104,031,960 (GRCm39) |
|
probably benign |
Het |
| Gm4340 |
CAGAAG |
CAGAAGAAG |
10: 104,031,927 (GRCm39) |
|
probably benign |
Het |
| Gpatch11 |
AGAGGA |
AGAGGATGAGGA |
17: 79,149,607 (GRCm39) |
|
probably benign |
Het |
| H1f6 |
TGTGG |
TG |
13: 23,879,896 (GRCm39) |
|
probably benign |
Homo |
| H2-Q4 |
G |
A |
17: 35,599,381 (GRCm39) |
D155N |
probably damaging |
Homo |
| Hoxa3 |
G |
GCTT |
6: 52,147,110 (GRCm39) |
|
probably benign |
Homo |
| Ifi208 |
ATGGTG |
ATG |
1: 173,505,264 (GRCm39) |
|
probably benign |
Homo |
| Ighv5-9 |
C |
T |
12: 113,625,497 (GRCm39) |
S82N |
probably benign |
Homo |
| Klra10 |
G |
A |
6: 130,249,710 (GRCm39) |
R192C |
probably benign |
Het |
| Kmt2b |
TCCTCC |
TCCTCCCCCTCC |
7: 30,285,800 (GRCm39) |
|
probably benign |
Het |
| Krt10 |
CGCC |
CGCCGCC |
11: 99,277,025 (GRCm39) |
|
probably benign |
Het |
| Krt10 |
ACC |
ACCCCC |
11: 99,277,029 (GRCm39) |
|
probably benign |
Homo |
| Lce1m |
CGCTGCTGCTGCCACAGCA |
C |
3: 92,925,554 (GRCm39) |
|
probably benign |
Het |
| Mak16 |
T |
G,A |
8: 31,651,777 (GRCm39) |
E203D |
probably benign |
Homo |
| Med12l |
AGC |
AGCGGC |
3: 59,183,409 (GRCm39) |
|
probably benign |
Het |
| Med12l |
AGCGGC |
AGCGGCGGC |
3: 59,183,415 (GRCm39) |
|
probably benign |
Het |
| Mn1 |
AGC |
AGCGGC |
5: 111,567,572 (GRCm39) |
|
probably benign |
Het |
| Nacad |
TC |
TCAGGGGC |
11: 6,549,762 (GRCm39) |
|
probably benign |
Het |
| Naip1 |
C |
T |
13: 100,561,979 (GRCm39) |
R1062K |
probably benign |
Het |
| Ndel1 |
G |
A |
11: 68,724,235 (GRCm39) |
P246L |
probably damaging |
Het |
| Nelfe |
AC |
ACAAAGAGCGGGATCGAGACAGAGCC |
17: 35,073,065 (GRCm39) |
|
probably benign |
Het |
| Or51q1 |
TCC |
TCCC |
7: 103,629,110 (GRCm39) |
|
probably null |
Het |
| Or5p70 |
A |
G |
7: 107,995,100 (GRCm39) |
T258A |
probably benign |
Het |
| Or5p70 |
G |
A |
7: 107,995,105 (GRCm39) |
M259I |
probably benign |
Het |
| P4ha2 |
GTGTTGCTG |
GTG |
11: 54,001,077 (GRCm39) |
|
probably benign |
Homo |
| Pde3b |
GGTGGTGGTG |
GGTGGTGGTGGTG |
7: 114,134,010 (GRCm39) |
|
probably benign |
Homo |
| Pdik1l |
ACCACC |
ACCACCCCCACC |
4: 134,006,820 (GRCm39) |
|
probably benign |
Homo |
| Phaf1 |
G |
A |
8: 105,967,730 (GRCm39) |
G207E |
probably benign |
Homo |
| Plekhs1 |
AGAC |
AGACCTCCCCCGCGAC |
19: 56,468,293 (GRCm39) |
|
probably benign |
Homo |
| Plekhs1 |
TCCAGAC |
TCCAGACCTCCCCCCAGAC |
19: 56,468,290 (GRCm39) |
|
probably benign |
Homo |
| Pramel16 |
AAGAG |
AAG |
4: 143,676,327 (GRCm39) |
|
probably null |
Het |
| Pramel16 |
G |
A |
4: 143,676,312 (GRCm39) |
T264M |
probably damaging |
Het |
| Pramel27 |
AA |
AATA |
4: 143,578,213 (GRCm39) |
|
probably null |
Homo |
| Prkn |
G |
A |
17: 12,073,650 (GRCm39) |
V323M |
probably damaging |
Homo |
| Ptms |
TCT |
TCTCCT |
6: 124,891,417 (GRCm39) |
|
probably benign |
Homo |
| Raet1d |
A |
G |
10: 22,247,458 (GRCm39) |
Q178R |
probably benign |
Het |
| Rtbdn |
AGCG |
AGCGCCGGCG |
8: 85,682,797 (GRCm39) |
|
probably benign |
Het |
| Rtbdn |
GC |
GCAGCGCC |
8: 85,682,807 (GRCm39) |
|
probably benign |
Het |
| Semp2l2a |
G |
C |
8: 13,887,613 (GRCm39) |
H159Q |
probably benign |
Het |
| Serac1 |
T |
A |
17: 6,121,083 (GRCm39) |
K70N |
probably damaging |
Homo |
| Sfswap |
CCCACTC |
CCCACTCAGACCACTC |
5: 129,646,821 (GRCm39) |
|
probably benign |
Homo |
| Sp110 |
ACT |
ACTGCT |
1: 85,515,209 (GRCm39) |
|
probably benign |
Het |
| Spaca1 |
GCTCTC |
GCTCTCACTCTC |
4: 34,049,838 (GRCm39) |
|
probably benign |
Het |
| Spag17 |
GGA |
GGATGA |
3: 99,963,565 (GRCm39) |
|
probably benign |
Het |
| Spag17 |
GGAGGAGGA |
GGAGGAGGAGGA |
3: 99,963,568 (GRCm39) |
|
probably benign |
Homo |
| Speer4a1 |
C |
A |
5: 26,241,746 (GRCm39) |
E127* |
probably null |
Het |
| Sry |
GGT |
GGTTGT |
Y: 2,662,836 (GRCm39) |
|
probably benign |
Het |
| Sry |
TGG |
TGGGGG |
Y: 2,662,835 (GRCm39) |
|
probably benign |
Het |
| Sry |
CTGCTGGTG |
CTG |
Y: 2,663,146 (GRCm39) |
|
probably benign |
Het |
| Sry |
GGT |
GGTAGT |
Y: 2,662,839 (GRCm39) |
|
probably benign |
Homo |
| Tdpoz3 |
C |
T |
3: 93,733,819 (GRCm39) |
P165S |
probably benign |
Het |
| Tdpoz4 |
GAA |
GA |
3: 93,704,187 (GRCm39) |
|
probably null |
Het |
| Tert |
AGGCC |
AGGCCAAGGGGGCC |
13: 73,796,419 (GRCm39) |
|
probably benign |
Homo |
| Tmbim7 |
C |
T |
5: 3,720,064 (GRCm39) |
R100C |
possibly damaging |
Homo |
| Tnfrsf9 |
CT |
CTGAT |
4: 151,018,851 (GRCm39) |
|
probably benign |
Homo |
| Tob1 |
AGC |
AGCCGC |
11: 94,105,298 (GRCm39) |
|
probably benign |
Het |
| Trav6n-5 |
GCTT |
G |
14: 53,342,369 (GRCm39) |
|
probably benign |
Homo |
| Triobp |
G |
GTCA |
15: 78,877,592 (GRCm39) |
|
probably benign |
Homo |
| Tsen2 |
AGG |
AGGTGG |
6: 115,537,033 (GRCm39) |
|
probably benign |
Het |
| Ubtf |
TCC |
TCCGCC |
11: 102,197,782 (GRCm39) |
|
probably benign |
Het |
| Ubtf |
TC |
TCCCC |
11: 102,197,785 (GRCm39) |
|
probably benign |
Het |
| Vmn2r125 |
G |
A |
4: 156,703,260 (GRCm39) |
V213I |
probably benign |
Het |
| Vmn2r87 |
C |
T |
10: 130,314,583 (GRCm39) |
M334I |
probably benign |
Homo |
| Zdhhc16 |
G |
A |
19: 41,930,588 (GRCm39) |
|
probably benign |
Het |
| Zfp28 |
G |
A |
7: 6,397,862 (GRCm39) |
G766R |
probably damaging |
Het |
| Zfp335 |
GTCGTC |
GTCGTCGTC |
2: 164,749,385 (GRCm39) |
|
probably benign |
Het |
| Zfp335 |
C |
CCCC |
2: 164,749,397 (GRCm39) |
|
probably benign |
Het |
| Zfp428 |
G |
A |
7: 24,214,506 (GRCm39) |
D41N |
probably damaging |
Homo |
| Zfp429 |
A |
T |
13: 67,544,769 (GRCm39) |
F48Y |
probably benign |
Het |
| Zfp598 |
CCACC |
CCACCCACACC |
17: 24,899,754 (GRCm39) |
|
probably benign |
Het |
| Zfp93 |
G |
A |
7: 23,975,011 (GRCm39) |
R332H |
possibly damaging |
Het |
| Zpld2 |
G |
GCTC |
4: 133,929,942 (GRCm39) |
|
probably benign |
Homo |
|
| Other mutations in Cluh |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00095:Cluh
|
APN |
11 |
74,554,890 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL00858:Cluh
|
APN |
11 |
74,550,431 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL01380:Cluh
|
APN |
11 |
74,556,772 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02402:Cluh
|
APN |
11 |
74,547,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02620:Cluh
|
APN |
11 |
74,555,893 (GRCm39) |
nonsense |
probably null |
|
|
IGL02990:Cluh
|
APN |
11 |
74,558,591 (GRCm39) |
splice site |
probably null |
|
|
IGL03163:Cluh
|
APN |
11 |
74,556,894 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL03208:Cluh
|
APN |
11 |
74,560,332 (GRCm39) |
splice site |
probably null |
|
|
IGL03293:Cluh
|
APN |
11 |
74,556,578 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL03408:Cluh
|
APN |
11 |
74,556,779 (GRCm39) |
missense |
probably benign |
0.06 |
|
spent
|
UTSW |
11 |
74,551,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4342:Cluh
|
UTSW |
11 |
74,560,350 (GRCm39) |
small insertion |
probably benign |
|
|
FR4449:Cluh
|
UTSW |
11 |
74,560,358 (GRCm39) |
small insertion |
probably benign |
|
|
FR4589:Cluh
|
UTSW |
11 |
74,560,357 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Cluh
|
UTSW |
11 |
74,560,350 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Cluh
|
UTSW |
11 |
74,560,345 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Cluh
|
UTSW |
11 |
74,560,340 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Cluh
|
UTSW |
11 |
74,560,359 (GRCm39) |
small insertion |
probably benign |
|
|
FR4976:Cluh
|
UTSW |
11 |
74,560,346 (GRCm39) |
small insertion |
probably benign |
|
|
R0147:Cluh
|
UTSW |
11 |
74,556,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0153:Cluh
|
UTSW |
11 |
74,548,176 (GRCm39) |
splice site |
probably benign |
|
|
R0506:Cluh
|
UTSW |
11 |
74,555,720 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0526:Cluh
|
UTSW |
11 |
74,556,812 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0834:Cluh
|
UTSW |
11 |
74,554,631 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1873:Cluh
|
UTSW |
11 |
74,552,902 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R1991:Cluh
|
UTSW |
11 |
74,550,355 (GRCm39) |
nonsense |
probably null |
|
|
R1992:Cluh
|
UTSW |
11 |
74,550,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2095:Cluh
|
UTSW |
11 |
74,552,550 (GRCm39) |
nonsense |
probably null |
|
|
R2101:Cluh
|
UTSW |
11 |
74,551,328 (GRCm39) |
splice site |
probably benign |
|
|
R2103:Cluh
|
UTSW |
11 |
74,550,355 (GRCm39) |
nonsense |
probably null |
|
|
R2220:Cluh
|
UTSW |
11 |
74,557,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3702:Cluh
|
UTSW |
11 |
74,556,182 (GRCm39) |
missense |
probably benign |
|
|
R3853:Cluh
|
UTSW |
11 |
74,547,279 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3900:Cluh
|
UTSW |
11 |
74,557,930 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4891:Cluh
|
UTSW |
11 |
74,555,885 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4895:Cluh
|
UTSW |
11 |
74,558,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5056:Cluh
|
UTSW |
11 |
74,552,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5089:Cluh
|
UTSW |
11 |
74,551,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5217:Cluh
|
UTSW |
11 |
74,550,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Cluh
|
UTSW |
11 |
74,556,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5382:Cluh
|
UTSW |
11 |
74,555,935 (GRCm39) |
intron |
probably benign |
|
|
R5516:Cluh
|
UTSW |
11 |
74,551,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5809:Cluh
|
UTSW |
11 |
74,552,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6146:Cluh
|
UTSW |
11 |
74,558,054 (GRCm39) |
splice site |
probably null |
|
|
R6326:Cluh
|
UTSW |
11 |
74,557,068 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6541:Cluh
|
UTSW |
11 |
74,548,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6674:Cluh
|
UTSW |
11 |
74,557,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6870:Cluh
|
UTSW |
11 |
74,556,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Cluh
|
UTSW |
11 |
74,552,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7086:Cluh
|
UTSW |
11 |
74,558,166 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7225:Cluh
|
UTSW |
11 |
74,557,232 (GRCm39) |
splice site |
probably null |
|
|
R7310:Cluh
|
UTSW |
11 |
74,560,285 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7317:Cluh
|
UTSW |
11 |
74,556,530 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7674:Cluh
|
UTSW |
11 |
74,558,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7941:Cluh
|
UTSW |
11 |
74,550,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9061:Cluh
|
UTSW |
11 |
74,551,192 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R9326:Cluh
|
UTSW |
11 |
74,554,902 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9489:Cluh
|
UTSW |
11 |
74,558,772 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9605:Cluh
|
UTSW |
11 |
74,558,772 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
RF020:Cluh
|
UTSW |
11 |
74,560,364 (GRCm39) |
small insertion |
probably benign |
|
|
RF032:Cluh
|
UTSW |
11 |
74,560,341 (GRCm39) |
small insertion |
probably benign |
|
|
X0028:Cluh
|
UTSW |
11 |
74,554,292 (GRCm39) |
missense |
probably benign |
0.26 |
|
Z1177:Cluh
|
UTSW |
11 |
74,558,580 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
Z1186:Cluh
|
UTSW |
11 |
74,560,357 (GRCm39) |
small insertion |
probably benign |
|
|
Z1186:Cluh
|
UTSW |
11 |
74,560,343 (GRCm39) |
small insertion |
probably benign |
|
|
Z1187:Cluh
|
UTSW |
11 |
74,560,340 (GRCm39) |
small insertion |
probably benign |
|
|
Z1187:Cluh
|
UTSW |
11 |
74,560,342 (GRCm39) |
small insertion |
probably benign |
|
|
Z1187:Cluh
|
UTSW |
11 |
74,560,343 (GRCm39) |
small insertion |
probably benign |
|
|
Z1187:Cluh
|
UTSW |
11 |
74,560,346 (GRCm39) |
small insertion |
probably benign |
|
|
Z1187:Cluh
|
UTSW |
11 |
74,560,347 (GRCm39) |
small insertion |
probably benign |
|
|
Z1187:Cluh
|
UTSW |
11 |
74,560,350 (GRCm39) |
small insertion |
probably benign |
|
|
Z1187:Cluh
|
UTSW |
11 |
74,560,355 (GRCm39) |
small insertion |
probably benign |
|
|
Z1188:Cluh
|
UTSW |
11 |
74,560,343 (GRCm39) |
small insertion |
probably benign |
|
|
Z1189:Cluh
|
UTSW |
11 |
74,560,340 (GRCm39) |
frame shift |
probably null |
|
|
Z1189:Cluh
|
UTSW |
11 |
74,560,357 (GRCm39) |
small insertion |
probably benign |
|
|
Z1189:Cluh
|
UTSW |
11 |
74,560,356 (GRCm39) |
nonsense |
probably null |
|
|
Z1189:Cluh
|
UTSW |
11 |
74,560,355 (GRCm39) |
small insertion |
probably benign |
|
|
Z1189:Cluh
|
UTSW |
11 |
74,560,349 (GRCm39) |
small insertion |
probably benign |
|
|
Z1189:Cluh
|
UTSW |
11 |
74,560,345 (GRCm39) |
small insertion |
probably benign |
|
|
Z1189:Cluh
|
UTSW |
11 |
74,560,343 (GRCm39) |
small insertion |
probably benign |
|
|
Z1190:Cluh
|
UTSW |
11 |
74,560,356 (GRCm39) |
small insertion |
probably benign |
|
|
Z1190:Cluh
|
UTSW |
11 |
74,560,344 (GRCm39) |
small insertion |
probably benign |
|
|
Z1190:Cluh
|
UTSW |
11 |
74,560,343 (GRCm39) |
small insertion |
probably benign |
|
|
Z1190:Cluh
|
UTSW |
11 |
74,560,358 (GRCm39) |
small insertion |
probably benign |
|
|
Z1191:Cluh
|
UTSW |
11 |
74,560,349 (GRCm39) |
small insertion |
probably benign |
|
|
Z1191:Cluh
|
UTSW |
11 |
74,560,343 (GRCm39) |
small insertion |
probably benign |
|
|
Z1191:Cluh
|
UTSW |
11 |
74,560,340 (GRCm39) |
small insertion |
probably benign |
|
|
Z1191:Cluh
|
UTSW |
11 |
74,560,356 (GRCm39) |
small insertion |
probably benign |
|
|
Z1191:Cluh
|
UTSW |
11 |
74,560,352 (GRCm39) |
small insertion |
probably benign |
|
|
Z1192:Cluh
|
UTSW |
11 |
74,560,351 (GRCm39) |
small insertion |
probably benign |
|
|
Z1192:Cluh
|
UTSW |
11 |
74,560,343 (GRCm39) |
small insertion |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGTGTCCTGAAAGCTGCAGG -3'
(R):5'- TTTTAGGGGCAGGCAAACCAG -3'
Sequencing Primer
(F):5'- TGAAAGCTGCAGGGTGCC -3'
(R):5'- GGTATAAAGTTGAGGACTAGCTTCC -3'
|
| Posted On |
2018-04-05 |
Incidental Mutation