Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01062:Vmn1r10'

51228

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r10

Ensembl Gene

ENSMUSG00000115181

Gene Name

vomeronasal 1 receptor 10

Synonyms

V1rc1

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.290) question?

Stock #

IGL01062

Quality Score

Status

Chromosome

Chromosomal Location

57090410-57091345 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 57090821 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Glycine at position 138 (S138G)

Ref Sequence

ENSEMBL: ENSMUSP00000154213 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000176073] [ENSMUST00000228270]

AlphaFold

W4VSP8

Predicted Effect

possibly damaging
Transcript: ENSMUST00000176073
AA Change: S138G

PolyPhen 2 Score 0.698 (Sensitivity: 0.86; Specificity: 0.92)

SMART Domains

Protein: ENSMUSP00000134901
Gene: ENSMUSG00000115181
AA Change: S138G

Domain	Start	End	E-Value	Type
Pfam:V1R	28	293	4.1e-55	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000228270
AA Change: S138G

PolyPhen 2 Score 0.698 (Sensitivity: 0.86; Specificity: 0.92)

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aen	G	A	7: 78,557,050 (GRCm39)	M299I	probably damaging	Het
Amer3	A	G	1: 34,625,820 (GRCm39)	K20E	probably damaging	Het
Arhgap31	A	G	16: 38,421,818 (GRCm39)	L1416P	probably damaging	Het
Avpr1a	G	A	10: 122,285,434 (GRCm39)	C242Y	probably damaging	Het
Bclaf3	T	C	X: 158,336,415 (GRCm39)	Y281H	probably benign	Het
Cdc14a	T	A	3: 116,068,361 (GRCm39)		probably benign	Het
Cfap206	C	T	4: 34,721,562 (GRCm39)	S162N	probably damaging	Het
Cntn4	T	C	6: 106,595,239 (GRCm39)		probably benign	Het
Cyp3a44	T	A	5: 145,731,149 (GRCm39)	D217V	possibly damaging	Het
Eprs1	A	G	1: 185,111,812 (GRCm39)	E274G	probably benign	Het
Ercc6l2	G	T	13: 63,995,268 (GRCm39)	Q354H	probably null	Het
Glb1l	A	T	1: 75,177,882 (GRCm39)	I392N	probably damaging	Het
Gm3173	T	C	14: 15,728,472 (GRCm39)		probably null	Het
Hadh	C	T	3: 131,034,640 (GRCm39)	V219M	probably damaging	Het
Hspb9	A	G	11: 100,604,761 (GRCm39)	H29R	possibly damaging	Het
Iqgap3	G	T	3: 88,017,429 (GRCm39)	V240L	probably benign	Het
Jmjd1c	T	C	10: 67,062,494 (GRCm39)	S1616P	probably damaging	Het
Knl1	A	G	2: 118,907,461 (GRCm39)	I1662V	probably benign	Het
Maco1	A	T	4: 134,560,608 (GRCm39)	V125E	probably damaging	Het
Mapre3	A	G	5: 31,022,240 (GRCm39)	I236V	probably benign	Het
Med17	T	C	9: 15,190,917 (GRCm39)	E58G	probably benign	Het
Myh6	T	C	14: 55,189,749 (GRCm39)	E1099G	probably damaging	Het
Myt1	T	A	2: 181,439,522 (GRCm39)	V348D	probably damaging	Het
Nat10	A	T	2: 103,573,393 (GRCm39)	I368N	probably damaging	Het
Nol6	T	C	4: 41,118,205 (GRCm39)	I811V	probably benign	Het
Oas1d	C	A	5: 121,057,127 (GRCm39)	Y244*	probably null	Het
Or6e1	A	T	14: 54,520,181 (GRCm39)	M57K	probably damaging	Het
Osbpl1a	A	G	18: 13,038,132 (GRCm39)	V273A	probably benign	Het
Pigw	T	C	11: 84,768,769 (GRCm39)	R187G	probably benign	Het
Plekhg5	G	A	4: 152,192,953 (GRCm39)	D603N	probably damaging	Het
Ptprk	T	C	10: 28,456,414 (GRCm39)	V1058A	probably damaging	Het
Robo4	G	A	9: 37,317,296 (GRCm39)	S537N	probably benign	Het
Rptn	T	A	3: 93,304,489 (GRCm39)	F607L	probably benign	Het
Sall1	A	G	8: 89,759,972 (GRCm39)	V44A	probably damaging	Het
Sh3bp4	C	A	1: 89,071,682 (GRCm39)	Q177K	probably benign	Het
Skic3	T	A	13: 76,303,581 (GRCm39)	L1225*	probably null	Het
Spmip6	T	A	4: 41,511,433 (GRCm39)	E93D	probably damaging	Het
Srrt	C	A	5: 137,294,569 (GRCm39)	G779V	probably damaging	Het
Tamalin	A	G	15: 101,126,777 (GRCm39)		probably benign	Het
Tex21	T	C	12: 76,245,718 (GRCm39)	D526G	probably benign	Het
Yars2	C	T	16: 16,124,406 (GRCm39)	R338*	probably null	Het
Zfp454	T	C	11: 50,765,033 (GRCm39)	E22G	probably benign	Het
Zzef1	T	A	11: 72,765,795 (GRCm39)	C1441S	probably benign	Het

Other mutations in Vmn1r10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL03255:Vmn1r10	APN	6	57,090,911 (GRCm39)	missense	probably benign	0.05
IGL03393:Vmn1r10	APN	6	57,091,042 (GRCm39)	nonsense	probably null
R0310:Vmn1r10	UTSW	6	57,090,486 (GRCm39)	missense	probably damaging	0.97
R2271:Vmn1r10	UTSW	6	57,091,088 (GRCm39)	missense	probably damaging	1.00
R2411:Vmn1r10	UTSW	6	57,091,124 (GRCm39)	missense	probably benign	0.14
R3700:Vmn1r10	UTSW	6	57,091,287 (GRCm39)	missense	probably benign	0.05
R3731:Vmn1r10	UTSW	6	57,090,719 (GRCm39)	missense	probably damaging	0.99
R4805:Vmn1r10	UTSW	6	57,090,602 (GRCm39)	missense	possibly damaging	0.94
R4922:Vmn1r10	UTSW	6	57,090,811 (GRCm39)	missense	probably damaging	0.99
R5697:Vmn1r10	UTSW	6	57,090,474 (GRCm39)	missense	probably damaging	1.00
R5936:Vmn1r10	UTSW	6	57,091,302 (GRCm39)	missense	probably benign	0.01
R6119:Vmn1r10	UTSW	6	57,091,218 (GRCm39)	missense	probably benign	0.01
R7107:Vmn1r10	UTSW	6	57,090,615 (GRCm39)	missense	possibly damaging	0.90
R7531:Vmn1r10	UTSW	6	57,090,924 (GRCm39)	missense	possibly damaging	0.90
R7635:Vmn1r10	UTSW	6	57,091,026 (GRCm39)	missense	probably benign	0.00
R7860:Vmn1r10	UTSW	6	57,090,686 (GRCm39)	missense	probably benign	0.19
R8786:Vmn1r10	UTSW	6	57,091,010 (GRCm39)	missense	probably benign	0.05
R9385:Vmn1r10	UTSW	6	57,090,833 (GRCm39)	missense	probably benign	0.01

Posted On

2013-06-21