Mutagenetix > Incidental Mutation

Incidental Mutation 'R6349:Fsip2'

512418

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

044503-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.108) question?

Stock #

R6349 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

82773978-82839281 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 82823416 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Methionine to Lysine at position 6383 (M6383K)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000132967

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000143764
AA Change: M6383K

PolyPhen 2 Score 0.051 (Sensitivity: 0.94; Specificity: 0.83)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: M6383K

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Coding Region Coverage

1x: 99.9%
3x: 99.5%
10x: 97.9%
20x: 93.6%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700012A03Rik	A	G	6: 32,028,595 (GRCm39)	Y9C	probably benign	Het
4930433I11Rik	A	C	7: 40,644,196 (GRCm39)	M622L	possibly damaging	Het
Abca8b	C	T	11: 109,825,544 (GRCm39)		probably null	Het
Adam28	T	C	14: 68,870,621 (GRCm39)	I351V	probably benign	Het
Adgrd1	A	C	5: 129,219,603 (GRCm39)		probably null	Het
Ank3	T	A	10: 69,815,269 (GRCm39)	I473N	probably damaging	Het
Ankrd6	A	T	4: 32,822,231 (GRCm39)	H179Q	probably damaging	Het
Ano6	A	G	15: 95,863,903 (GRCm39)	R808G	probably damaging	Het
Anxa8	A	T	14: 33,819,850 (GRCm39)	I280F	probably damaging	Het
Asb2	C	T	12: 103,312,118 (GRCm39)	M1I	probably null	Het
Astn1	C	T	1: 158,491,691 (GRCm39)	Q1023*	probably null	Het
Cast	T	A	13: 74,869,314 (GRCm39)	E542D	probably damaging	Het
Ccdc162	C	T	10: 41,570,396 (GRCm39)	E30K	probably damaging	Het
Ccdc87	T	C	19: 4,891,347 (GRCm39)	V613A	probably damaging	Het
Cdk13	T	C	13: 17,926,304 (GRCm39)	N832S	probably damaging	Het
Celsr1	T	A	15: 85,915,885 (GRCm39)	N696I	probably damaging	Het
Chd3	T	C	11: 69,254,857 (GRCm39)	E161G	possibly damaging	Het
Cxcr4	C	A	1: 128,517,014 (GRCm39)	V216F	possibly damaging	Het
Cyp4a10	A	G	4: 115,382,555 (GRCm39)	I282V	probably benign	Het
Deaf1	T	C	7: 140,902,863 (GRCm39)	T154A	possibly damaging	Het
Dido1	A	T	2: 180,302,494 (GRCm39)	D1803E	probably benign	Het
Dmxl2	T	C	9: 54,327,193 (GRCm39)	D944G	possibly damaging	Het
Dnah5	G	A	15: 28,238,657 (GRCm39)	V400M	probably damaging	Het
Fbxo15	A	G	18: 84,982,267 (GRCm39)	I240V	probably benign	Het
Fcrl2	A	G	3: 87,159,803 (GRCm39)	C484R	probably damaging	Het
Fech	G	T	18: 64,603,856 (GRCm39)	Y164*	probably null	Het
Fer1l5	T	A	1: 36,450,355 (GRCm39)	W1175R	probably damaging	Het
Fgfrl1	T	C	5: 108,853,372 (GRCm39)	Y241H	probably damaging	Het
Flvcr2	T	C	12: 85,793,974 (GRCm39)	Y117H	probably benign	Het
Gcc2	T	A	10: 58,105,296 (GRCm39)	D141E	probably benign	Het
Glt1d1	A	C	5: 127,783,950 (GRCm39)	R301S	probably benign	Het
Hars1	G	C	18: 36,916,107 (GRCm39)	A16G	probably benign	Het
Hmcn2	G	T	2: 31,278,385 (GRCm39)	G1696C	probably damaging	Het
Hydin	T	A	8: 111,145,091 (GRCm39)	L814*	probably null	Het
Izumo4	T	A	10: 80,538,551 (GRCm39)	M1K	probably null	Het
Kdm5d	T	A	Y: 916,847 (GRCm39)	M414K	probably damaging	Homo
Kif21b	G	A	1: 136,086,064 (GRCm39)	V812I	probably damaging	Het
Map3k7	A	G	4: 31,988,661 (GRCm39)	D270G	possibly damaging	Het
Mical3	A	G	6: 120,936,486 (GRCm39)	S1347P	probably benign	Het
Mras	T	A	9: 99,276,669 (GRCm39)	D67V	probably damaging	Het
Mtnr1b	A	T	9: 15,774,509 (GRCm39)	Y183*	probably null	Het
Muc16	A	T	9: 18,568,625 (GRCm39)	L1298Q	unknown	Het
Myh2	A	T	11: 67,083,829 (GRCm39)	I1536F	probably benign	Het
Or7c19	T	C	8: 85,957,787 (GRCm39)	I221T	possibly damaging	Het
Osmr	G	T	15: 6,850,544 (GRCm39)	D686E	probably benign	Het
Pah	T	A	10: 87,414,831 (GRCm39)	D394E	probably benign	Het
Pla1a	T	A	16: 38,237,486 (GRCm39)	S71C	probably benign	Het
Proc	T	A	18: 32,266,486 (GRCm39)	I114L	probably benign	Het
Psd	T	G	19: 46,301,826 (GRCm39)		probably null	Het
Psmb6	C	T	11: 70,418,364 (GRCm39)	Q226*	probably null	Het
Rnpepl1	A	T	1: 92,847,563 (GRCm39)	N717Y	probably damaging	Het
Rundc1	T	C	11: 101,324,988 (GRCm39)	S565P	probably benign	Het
Serpinb5	T	A	1: 106,809,495 (GRCm39)	S300R	probably benign	Het
Serpinf2	T	C	11: 75,323,257 (GRCm39)	D483G	probably damaging	Het
Sgsm3	T	C	15: 80,892,547 (GRCm39)	I291T	probably benign	Het
Smg6	T	A	11: 74,944,600 (GRCm39)	D116E	possibly damaging	Het
Srfbp1	G	T	18: 52,622,034 (GRCm39)	S365I	probably benign	Het
Stkld1	A	G	2: 26,835,872 (GRCm39)	T236A	probably benign	Het
Susd5	T	C	9: 113,924,870 (GRCm39)	V251A	probably benign	Het
Tcf25	A	G	8: 124,118,332 (GRCm39)	Y314C	probably damaging	Het
Tmem210	A	G	2: 25,179,048 (GRCm39)	D112G	possibly damaging	Het
Tubb2b	A	G	13: 34,311,528 (GRCm39)	Y422H	probably damaging	Het
Tyw1	T	C	5: 130,305,872 (GRCm39)	S332P	possibly damaging	Het
Vmn1r29	A	C	6: 58,284,412 (GRCm39)	Q44P	probably damaging	Het
Vrtn	T	C	12: 84,695,792 (GRCm39)	S181P	probably damaging	Het
Wdr76	T	A	2: 121,364,712 (GRCm39)	Y437N	possibly damaging	Het
Zc3h18	C	A	8: 123,135,025 (GRCm39)		probably benign	Het
Zfp287	G	T	11: 62,616,168 (GRCm39)	D174E	probably damaging	Het
Zfp800	A	T	6: 28,244,601 (GRCm39)	Y121*	probably null	Het
Zfyve19	T	A	2: 119,041,078 (GRCm39)	L57Q	probably damaging	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,820,730 (GRCm39)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,821,657 (GRCm39)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,830,163 (GRCm39)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,823,326 (GRCm39)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,807,863 (GRCm39)	missense	probably benign
IGL01554:Fsip2	APN	2	82,807,622 (GRCm39)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,821,430 (GRCm39)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,808,691 (GRCm39)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,812,983 (GRCm39)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,815,273 (GRCm39)	missense	probably benign
IGL01918:Fsip2	APN	2	82,822,482 (GRCm39)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,824,349 (GRCm39)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,824,211 (GRCm39)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,822,204 (GRCm39)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,809,065 (GRCm39)	missense	probably benign
IGL02155:Fsip2	APN	2	82,828,696 (GRCm39)	missense	probably benign
IGL02219:Fsip2	APN	2	82,808,174 (GRCm39)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,813,116 (GRCm39)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,809,137 (GRCm39)	missense	probably benign
IGL02478:Fsip2	APN	2	82,814,736 (GRCm39)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,809,199 (GRCm39)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,822,347 (GRCm39)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,779,836 (GRCm39)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,823,407 (GRCm39)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,828,662 (GRCm39)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,812,501 (GRCm39)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,781,370 (GRCm39)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,823,839 (GRCm39)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,822,701 (GRCm39)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,813,398 (GRCm39)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,820,968 (GRCm39)	intron	probably benign
IGL03076:Fsip2	APN	2	82,812,482 (GRCm39)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,808,420 (GRCm39)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,807,737 (GRCm39)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,820,814 (GRCm39)	missense	probably benign
bubblegum	UTSW	2	82,823,184 (GRCm39)	missense	probably benign	0.16
Dao	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
engulf	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
envelope	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
gladius	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
glove	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
Katana	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
scarf	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
Sock	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
swaddle	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
wrap	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
Wrapper	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,818,756 (GRCm39)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,814,709 (GRCm39)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,814,706 (GRCm39)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,821,196 (GRCm39)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,830,201 (GRCm39)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,806,952 (GRCm39)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,815,269 (GRCm39)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,821,465 (GRCm39)	missense	probably benign
R0149:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,811,151 (GRCm39)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,815,521 (GRCm39)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,816,240 (GRCm39)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,813,677 (GRCm39)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,814,908 (GRCm39)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,821,419 (GRCm39)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,808,129 (GRCm39)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,777,296 (GRCm39)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,824,139 (GRCm39)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,807,877 (GRCm39)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,774,484 (GRCm39)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,819,302 (GRCm39)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,807,241 (GRCm39)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,816,513 (GRCm39)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,821,703 (GRCm39)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,812,683 (GRCm39)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,816,617 (GRCm39)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,815,828 (GRCm39)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,828,375 (GRCm39)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,819,780 (GRCm39)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,818,805 (GRCm39)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,805,378 (GRCm39)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,821,844 (GRCm39)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,805,570 (GRCm39)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,805,361 (GRCm39)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,811,355 (GRCm39)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,820,107 (GRCm39)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,819,752 (GRCm39)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,820,089 (GRCm39)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,828,407 (GRCm39)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,817,539 (GRCm39)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,810,155 (GRCm39)	missense	probably benign
R1520:Fsip2	UTSW	2	82,811,058 (GRCm39)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,811,931 (GRCm39)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,816,626 (GRCm39)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,808,861 (GRCm39)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,816,689 (GRCm39)	missense	probably benign
R1700:Fsip2	UTSW	2	82,822,081 (GRCm39)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,805,289 (GRCm39)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,820,256 (GRCm39)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,818,055 (GRCm39)	missense	possibly damaging	0.71
R1760:Fsip2	UTSW	2	82,815,240 (GRCm39)	missense	probably benign	0.07
R1760:Fsip2	UTSW	2	82,830,185 (GRCm39)	missense	possibly damaging	0.85
R1789:Fsip2	UTSW	2	82,807,906 (GRCm39)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,814,933 (GRCm39)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,823,601 (GRCm39)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,811,127 (GRCm39)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,817,077 (GRCm39)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,810,902 (GRCm39)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,821,894 (GRCm39)	missense	probably benign
R1965:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,810,175 (GRCm39)	missense	probably benign
R1988:Fsip2	UTSW	2	82,806,861 (GRCm39)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,819,788 (GRCm39)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R2037:Fsip2	UTSW	2	82,808,856 (GRCm39)	missense	probably damaging	0.99
R2070:Fsip2	UTSW	2	82,806,699 (GRCm39)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	82,839,159 (GRCm39)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,818,923 (GRCm39)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,820,615 (GRCm39)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,807,823 (GRCm39)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,793,095 (GRCm39)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,805,437 (GRCm39)	missense	probably benign
R2344:Fsip2	UTSW	2	82,820,257 (GRCm39)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,806,593 (GRCm39)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,811,064 (GRCm39)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,815,685 (GRCm39)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,809,954 (GRCm39)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,782,001 (GRCm39)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,808,511 (GRCm39)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,820,775 (GRCm39)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,809,389 (GRCm39)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,821,868 (GRCm39)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,816,854 (GRCm39)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,822,354 (GRCm39)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,817,071 (GRCm39)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,815,253 (GRCm39)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,819,311 (GRCm39)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,808,561 (GRCm39)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,813,058 (GRCm39)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,781,290 (GRCm39)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,819,950 (GRCm39)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,816,759 (GRCm39)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,789,006 (GRCm39)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,813,862 (GRCm39)	missense	probably benign
R4042:Fsip2	UTSW	2	82,813,896 (GRCm39)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,813,245 (GRCm39)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,817,413 (GRCm39)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,808,201 (GRCm39)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,821,550 (GRCm39)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4458:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,782,009 (GRCm39)	missense	probably benign
R4549:Fsip2	UTSW	2	82,819,972 (GRCm39)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,815,297 (GRCm39)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,816,510 (GRCm39)	missense	possibly damaging	0.71
R4583:Fsip2	UTSW	2	82,809,017 (GRCm39)	missense	probably benign	0.33
R4618:Fsip2	UTSW	2	82,818,103 (GRCm39)	missense	probably benign
R4700:Fsip2	UTSW	2	82,817,373 (GRCm39)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,805,203 (GRCm39)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,805,697 (GRCm39)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,819,629 (GRCm39)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,812,452 (GRCm39)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,818,044 (GRCm39)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,818,786 (GRCm39)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,820,515 (GRCm39)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,815,815 (GRCm39)	missense	probably benign	0.26
R4840:Fsip2	UTSW	2	82,779,739 (GRCm39)	missense	probably benign	0.01
R4865:Fsip2	UTSW	2	82,821,295 (GRCm39)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,805,202 (GRCm39)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,818,438 (GRCm39)	missense	probably benign	0.02
R4911:Fsip2	UTSW	2	82,811,837 (GRCm39)	missense	possibly damaging	0.85
R4918:Fsip2	UTSW	2	82,824,114 (GRCm39)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,815,384 (GRCm39)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,807,758 (GRCm39)	missense	probably benign	0.03
R4950:Fsip2	UTSW	2	82,777,276 (GRCm39)	missense	probably damaging	0.97
R4959:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,816,222 (GRCm39)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,809,773 (GRCm39)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,819,477 (GRCm39)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,818,836 (GRCm39)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,821,460 (GRCm39)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,822,329 (GRCm39)	missense	probably benign
R5119:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,811,768 (GRCm39)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,808,916 (GRCm39)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,813,338 (GRCm39)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,823,505 (GRCm39)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,808,925 (GRCm39)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,818,489 (GRCm39)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,820,185 (GRCm39)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,805,742 (GRCm39)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,821,262 (GRCm39)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,812,572 (GRCm39)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,810,230 (GRCm39)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,815,654 (GRCm39)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,815,542 (GRCm39)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,781,256 (GRCm39)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,781,252 (GRCm39)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,793,090 (GRCm39)	missense	probably benign
R5568:Fsip2	UTSW	2	82,816,908 (GRCm39)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,828,472 (GRCm39)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,818,439 (GRCm39)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,817,838 (GRCm39)	nonsense	probably null
R5712:Fsip2	UTSW	2	82,839,192 (GRCm39)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,808,260 (GRCm39)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,815,084 (GRCm39)	missense	probably benign
R5881:Fsip2	UTSW	2	82,814,785 (GRCm39)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,822,953 (GRCm39)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,818,852 (GRCm39)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,817,092 (GRCm39)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,807,835 (GRCm39)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,793,657 (GRCm39)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,820,812 (GRCm39)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,818,283 (GRCm39)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,822,471 (GRCm39)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,816,017 (GRCm39)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,809,777 (GRCm39)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,821,388 (GRCm39)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,824,112 (GRCm39)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,818,289 (GRCm39)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,817,601 (GRCm39)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,811,071 (GRCm39)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,812,798 (GRCm39)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,820,227 (GRCm39)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,810,785 (GRCm39)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,819,242 (GRCm39)	missense	probably benign	0.16
R6351:Fsip2	UTSW	2	82,823,028 (GRCm39)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,813,836 (GRCm39)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,812,657 (GRCm39)	missense	probably benign
R6621:Fsip2	UTSW	2	82,820,158 (GRCm39)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,813,571 (GRCm39)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,798,161 (GRCm39)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,809,878 (GRCm39)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,816,776 (GRCm39)	missense	probably benign
R6790:Fsip2	UTSW	2	82,821,283 (GRCm39)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,811,303 (GRCm39)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,815,544 (GRCm39)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,813,969 (GRCm39)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R6945:Fsip2	UTSW	2	82,823,184 (GRCm39)	missense	probably benign	0.16
R6950:Fsip2	UTSW	2	82,816,332 (GRCm39)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,809,061 (GRCm39)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,778,630 (GRCm39)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,807,298 (GRCm39)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,817,269 (GRCm39)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,820,979 (GRCm39)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,821,235 (GRCm39)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,811,078 (GRCm39)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,813,496 (GRCm39)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,817,968 (GRCm39)	missense	probably benign
R7126:Fsip2	UTSW	2	82,813,485 (GRCm39)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,813,085 (GRCm39)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,811,541 (GRCm39)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,816,571 (GRCm39)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,823,581 (GRCm39)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,819,412 (GRCm39)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,814,015 (GRCm39)	missense	probably benign
R7228:Fsip2	UTSW	2	82,822,651 (GRCm39)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,812,484 (GRCm39)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,823,607 (GRCm39)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,809,425 (GRCm39)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,812,474 (GRCm39)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,810,863 (GRCm39)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,820,035 (GRCm39)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,813,462 (GRCm39)	missense	probably benign
R7343:Fsip2	UTSW	2	82,809,711 (GRCm39)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,819,140 (GRCm39)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,820,663 (GRCm39)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,815,601 (GRCm39)	missense	possibly damaging	0.53
R7426:Fsip2	UTSW	2	82,810,441 (GRCm39)	missense	probably damaging	0.98
R7450:Fsip2	UTSW	2	82,782,024 (GRCm39)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,818,894 (GRCm39)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,815,196 (GRCm39)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,824,337 (GRCm39)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,819,361 (GRCm39)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,805,585 (GRCm39)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,817,256 (GRCm39)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,812,149 (GRCm39)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,820,455 (GRCm39)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,811,252 (GRCm39)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,818,723 (GRCm39)	missense	probably benign
R7811:Fsip2	UTSW	2	82,828,797 (GRCm39)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,807,044 (GRCm39)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,808,168 (GRCm39)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,781,365 (GRCm39)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,816,120 (GRCm39)	missense	possibly damaging	0.51
R8009:Fsip2	UTSW	2	82,818,793 (GRCm39)	missense	possibly damaging	0.85
R8031:Fsip2	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
R8034:Fsip2	UTSW	2	82,819,699 (GRCm39)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,816,322 (GRCm39)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,789,017 (GRCm39)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,823,296 (GRCm39)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,806,141 (GRCm39)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,818,021 (GRCm39)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,815,088 (GRCm39)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,806,951 (GRCm39)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,820,808 (GRCm39)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,808,487 (GRCm39)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,811,346 (GRCm39)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,818,724 (GRCm39)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,821,099 (GRCm39)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,818,198 (GRCm39)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,822,239 (GRCm39)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8419:Fsip2	UTSW	2	82,808,963 (GRCm39)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,811,910 (GRCm39)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,807,430 (GRCm39)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8459:Fsip2	UTSW	2	82,810,022 (GRCm39)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,810,284 (GRCm39)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,777,336 (GRCm39)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,821,871 (GRCm39)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,815,246 (GRCm39)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,811,453 (GRCm39)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,815,822 (GRCm39)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,813,453 (GRCm39)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,821,606 (GRCm39)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,820,782 (GRCm39)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,809,524 (GRCm39)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,807,681 (GRCm39)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,816,984 (GRCm39)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,810,938 (GRCm39)	missense	probably benign
R8926:Fsip2	UTSW	2	82,823,927 (GRCm39)	missense	possibly damaging	0.84
R8991:Fsip2	UTSW	2	82,815,370 (GRCm39)	missense	probably benign	0.33
R9014:Fsip2	UTSW	2	82,806,898 (GRCm39)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,817,075 (GRCm39)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,828,545 (GRCm39)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,806,180 (GRCm39)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,807,301 (GRCm39)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,816,103 (GRCm39)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,813,170 (GRCm39)	missense	probably benign
R9149:Fsip2	UTSW	2	82,812,374 (GRCm39)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,815,574 (GRCm39)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,817,844 (GRCm39)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,820,425 (GRCm39)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,823,062 (GRCm39)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,815,958 (GRCm39)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,807,662 (GRCm39)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,818,604 (GRCm39)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,818,747 (GRCm39)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,811,039 (GRCm39)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,822,756 (GRCm39)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,819,793 (GRCm39)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,805,907 (GRCm39)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,816,702 (GRCm39)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,806,132 (GRCm39)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,817,285 (GRCm39)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,793,062 (GRCm39)	missense	probably benign
R9523:Fsip2	UTSW	2	82,807,972 (GRCm39)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,798,173 (GRCm39)	missense	probably benign
R9636:Fsip2	UTSW	2	82,820,563 (GRCm39)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,821,984 (GRCm39)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,819,272 (GRCm39)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,806,226 (GRCm39)	missense	probably benign
R9705:Fsip2	UTSW	2	82,823,634 (GRCm39)	missense	probably benign
R9739:Fsip2	UTSW	2	82,823,896 (GRCm39)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,818,241 (GRCm39)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,821,994 (GRCm39)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,810,225 (GRCm39)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,821,865 (GRCm39)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,822,876 (GRCm39)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,808,184 (GRCm39)	missense	probably benign
RF028:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,812,851 (GRCm39)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,781,364 (GRCm39)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,785,290 (GRCm39)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,807,122 (GRCm39)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,817,807 (GRCm39)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,818,978 (GRCm39)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,817,997 (GRCm39)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,805,792 (GRCm39)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,820,009 (GRCm39)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,814,868 (GRCm39)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,777,304 (GRCm39)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,817,547 (GRCm39)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- TGTACAACCTGTGAAGGAATCAG -3'
(R):5'- GGGACCAGGTGTCTTTACTAG -3'

Sequencing Primer
(F):5'- ATCAGAAGCTGTGCCTTCAG -3'
(R):5'- AGCTTCCTCTAAAACTCTGGAG -3'

Posted On

2018-04-27