Incidental Mutation 'R6362:Dsc2'
| ID |
512556 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2a, Dsc2b |
| MMRRC Submission |
044512-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6362 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
20163690-20192611 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
A to T
at 20168520 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Stop codon
at position 45
(Y45*)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000039247
AA Change: Y646*
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: Y646*
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000075214
AA Change: Y646*
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: Y646*
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128464
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000155407
AA Change: Y45*
|
| SMART Domains |
Protein: ENSMUSP00000116063
Gene: ENSMUSG00000024331
AA Change: Y45*
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1l3wa5
|
2 |
71 |
2e-3 |
SMART |
|
Blast:CA
|
2 |
76 |
2e-47 |
BLAST |
|
transmembrane domain
|
96 |
118 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.9640 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.7%
- 10x: 98.5%
- 20x: 96.0%
|
| Validation Efficiency |
99% (78/79) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aldh5a1 |
T |
G |
13: 25,102,533 (GRCm39) |
D310A |
probably benign |
Het |
| Als2cl |
T |
A |
9: 110,724,514 (GRCm39) |
|
probably null |
Het |
| Amacr |
C |
A |
15: 10,984,891 (GRCm39) |
R170S |
probably damaging |
Het |
| Brwd1 |
C |
T |
16: 95,803,507 (GRCm39) |
R2221Q |
probably damaging |
Het |
| Cacna1g |
A |
T |
11: 94,330,533 (GRCm39) |
|
probably null |
Het |
| Cd3d |
G |
A |
9: 44,897,589 (GRCm39) |
D157N |
probably damaging |
Het |
| Cep131 |
T |
C |
11: 119,955,516 (GRCm39) |
D1043G |
probably damaging |
Het |
| Cimip1 |
T |
G |
2: 173,369,967 (GRCm39) |
|
probably null |
Het |
| Cit |
A |
G |
5: 116,024,735 (GRCm39) |
D326G |
probably benign |
Het |
| Col16a1 |
G |
C |
4: 129,959,983 (GRCm39) |
G370R |
unknown |
Het |
| Col6a3 |
T |
A |
1: 90,738,285 (GRCm39) |
Y1078F |
probably damaging |
Het |
| Colgalt2 |
A |
C |
1: 152,347,549 (GRCm39) |
Y161S |
probably damaging |
Het |
| Cyp2j13 |
A |
G |
4: 95,959,932 (GRCm39) |
Y75H |
probably damaging |
Het |
| Daxx |
G |
A |
17: 34,130,338 (GRCm39) |
V118I |
probably damaging |
Het |
| Dennd5a |
G |
T |
7: 109,533,472 (GRCm39) |
C75* |
probably null |
Het |
| Diaph3 |
A |
G |
14: 87,009,566 (GRCm39) |
L1071P |
probably damaging |
Het |
| Disp3 |
A |
G |
4: 148,338,765 (GRCm39) |
L802P |
possibly damaging |
Het |
| Dmc1 |
A |
G |
15: 79,473,024 (GRCm39) |
V141A |
probably benign |
Het |
| Dspp |
A |
G |
5: 104,323,900 (GRCm39) |
I348V |
probably benign |
Het |
| Epb42 |
C |
A |
2: 120,856,260 (GRCm39) |
C428F |
possibly damaging |
Het |
| Fam227a |
G |
T |
15: 79,527,551 (GRCm39) |
P100Q |
possibly damaging |
Het |
| Fer1l4 |
C |
T |
2: 155,890,170 (GRCm39) |
V252I |
probably benign |
Het |
| Fhod1 |
C |
A |
8: 106,058,273 (GRCm39) |
|
probably null |
Het |
| Fhod3 |
G |
T |
18: 24,887,312 (GRCm39) |
A68S |
probably benign |
Het |
| Gatm |
T |
C |
2: 122,428,677 (GRCm39) |
D328G |
probably benign |
Het |
| Gm6401 |
G |
T |
14: 41,789,727 (GRCm39) |
H44N |
probably benign |
Het |
| Gpat2 |
G |
C |
2: 127,273,838 (GRCm39) |
G294R |
possibly damaging |
Het |
| Gpr84 |
G |
A |
15: 103,216,937 (GRCm39) |
A380V |
probably damaging |
Het |
| Herc1 |
G |
T |
9: 66,379,190 (GRCm39) |
W3492L |
probably damaging |
Het |
| Hjurp |
A |
T |
1: 88,202,772 (GRCm39) |
Y71N |
possibly damaging |
Het |
| Jag2 |
T |
A |
12: 112,883,742 (GRCm39) |
K246N |
probably damaging |
Het |
| Klhl32 |
T |
C |
4: 24,629,195 (GRCm39) |
D524G |
probably null |
Het |
| Lax1 |
A |
G |
1: 133,608,334 (GRCm39) |
S136P |
possibly damaging |
Het |
| Lefty1 |
A |
G |
1: 180,764,725 (GRCm39) |
K217E |
probably benign |
Het |
| Lgr5 |
A |
G |
10: 115,314,430 (GRCm39) |
L169P |
probably damaging |
Het |
| Lrrc37 |
G |
C |
11: 103,511,478 (GRCm39) |
N163K |
unknown |
Het |
| Mad1l1 |
A |
T |
5: 140,300,810 (GRCm39) |
S29T |
possibly damaging |
Het |
| Man1a |
T |
C |
10: 53,950,891 (GRCm39) |
H77R |
probably benign |
Het |
| Met |
C |
T |
6: 17,558,732 (GRCm39) |
S1120F |
probably damaging |
Het |
| Mfsd4b2 |
A |
T |
10: 39,797,605 (GRCm39) |
I250N |
probably damaging |
Het |
| Myod1 |
A |
G |
7: 46,026,305 (GRCm39) |
H70R |
possibly damaging |
Het |
| Neb |
T |
C |
2: 52,102,704 (GRCm39) |
N4280S |
probably benign |
Het |
| Nudt6 |
T |
C |
3: 37,473,638 (GRCm39) |
T28A |
possibly damaging |
Het |
| Nup85 |
A |
G |
11: 115,474,560 (GRCm39) |
E628G |
probably damaging |
Het |
| Oaz3 |
A |
T |
3: 94,342,295 (GRCm39) |
D120E |
probably damaging |
Het |
| Or2y3 |
A |
T |
17: 38,393,620 (GRCm39) |
M83K |
probably damaging |
Het |
| Or5b102 |
A |
T |
19: 13,040,709 (GRCm39) |
|
probably benign |
Het |
| Or5be3 |
C |
T |
2: 86,863,633 (GRCm39) |
A311T |
probably benign |
Het |
| Or5m8 |
C |
A |
2: 85,822,285 (GRCm39) |
N41K |
probably damaging |
Het |
| Or6c1b |
A |
C |
10: 129,272,812 (GRCm39) |
I44L |
probably damaging |
Het |
| Osbpl8 |
A |
T |
10: 111,108,929 (GRCm39) |
K404* |
probably null |
Het |
| Pcdhga2 |
A |
G |
18: 37,803,958 (GRCm39) |
N601D |
probably damaging |
Het |
| Pld2 |
T |
C |
11: 70,445,501 (GRCm39) |
Y638H |
probably damaging |
Het |
| Pramel27 |
A |
G |
4: 143,579,435 (GRCm39) |
Y340C |
probably damaging |
Het |
| Prickle2 |
C |
G |
6: 92,435,596 (GRCm39) |
V2L |
possibly damaging |
Het |
| Psmd6 |
G |
A |
14: 14,116,949 (GRCm38) |
R125C |
probably benign |
Het |
| Rnaset2b |
G |
A |
17: 7,259,093 (GRCm39) |
V24I |
probably benign |
Het |
| Rusc2 |
A |
T |
4: 43,416,416 (GRCm39) |
D574V |
probably benign |
Het |
| Scn8a |
T |
A |
15: 100,837,996 (GRCm39) |
|
probably null |
Het |
| Sec11a |
T |
C |
7: 80,572,879 (GRCm39) |
E134G |
probably benign |
Het |
| Senp5 |
A |
G |
16: 31,808,702 (GRCm39) |
V157A |
probably damaging |
Het |
| Shkbp1 |
C |
T |
7: 27,051,120 (GRCm39) |
|
probably null |
Het |
| Slc43a1 |
T |
C |
2: 84,690,128 (GRCm39) |
L435P |
probably damaging |
Het |
| Spn |
G |
A |
7: 126,735,895 (GRCm39) |
P204L |
possibly damaging |
Het |
| Srr |
T |
A |
11: 74,801,028 (GRCm39) |
Q173L |
probably damaging |
Het |
| Star |
C |
G |
8: 26,301,835 (GRCm39) |
T222S |
probably benign |
Het |
| Timm22 |
T |
A |
11: 76,301,953 (GRCm39) |
Y93N |
probably damaging |
Het |
| Tmc4 |
G |
T |
7: 3,678,458 (GRCm39) |
Q58K |
probably benign |
Het |
| Tmem86b |
C |
T |
7: 4,632,835 (GRCm39) |
M1I |
probably null |
Het |
| Tmtc2 |
A |
T |
10: 105,205,831 (GRCm39) |
I488N |
probably damaging |
Het |
| Tnxb |
A |
T |
17: 34,913,362 (GRCm39) |
Y1792F |
probably damaging |
Het |
| Tph1 |
T |
A |
7: 46,296,867 (GRCm39) |
R443W |
possibly damaging |
Het |
| Ttyh1 |
T |
A |
7: 4,132,323 (GRCm39) |
V253E |
possibly damaging |
Het |
| Usf3 |
A |
G |
16: 44,038,940 (GRCm39) |
D1140G |
probably benign |
Het |
| Usp10 |
T |
C |
8: 120,668,055 (GRCm39) |
S118P |
probably benign |
Het |
| Vmn2r63 |
C |
T |
7: 42,552,721 (GRCm39) |
C845Y |
probably benign |
Het |
| Vmn2r72 |
G |
T |
7: 85,400,382 (GRCm39) |
F222L |
probably damaging |
Het |
| Zfp654 |
G |
A |
16: 64,606,457 (GRCm39) |
Q582* |
probably null |
Het |
| Zfp791 |
C |
T |
8: 85,846,279 (GRCm39) |
|
probably benign |
Het |
| Zfp879 |
T |
A |
11: 50,729,302 (GRCm39) |
D32V |
probably damaging |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,174,854 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,168,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,167,740 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,176,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,181,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,180,214 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,171,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,179,399 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,176,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,178,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,174,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,180,136 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,179,300 (GRCm39) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,179,334 (GRCm39) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,166,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,184,283 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,174,594 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,174,509 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,183,116 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,166,352 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,165,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,178,622 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,167,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,183,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,179,303 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,165,456 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,178,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,168,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,178,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,178,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,165,408 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,183,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,183,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,167,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,168,360 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,179,336 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,168,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,165,567 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,180,165 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,178,487 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6433:Dsc2
|
UTSW |
18 |
20,184,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,179,295 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,165,335 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,183,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,168,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,184,236 (GRCm39) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,168,392 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,174,983 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,168,451 (GRCm39) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,183,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,174,835 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,373 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,183,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,179,342 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,167,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,167,722 (GRCm39) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,171,151 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,176,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,167,764 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,174,773 (GRCm39) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,180,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,171,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,179,361 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,168,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTATCACTTTTCAGACCACTACC -3'
(R):5'- AGGCTTTCAGTTCAGCTACAG -3'
Sequencing Primer
(F):5'- TCACTTTTCAGACCACTACCTATAAG -3'
(R):5'- GCTACAGCTTCAGGAAGGATCC -3'
|
| Posted On |
2018-04-27 |
Incidental Mutation