Incidental Mutation 'R6351:Fam186a'
| ID |
514289 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fam186a
|
| Ensembl Gene |
ENSMUSG00000045350 |
| Gene Name |
family with sequence similarity 186, member A |
| Synonyms |
LOC380973, 1700030F18Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.059)
|
| Stock # |
R6351 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
99816229-99864942 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 99839623 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Arginine
at position 2207
(L2207R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097783
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000100209]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000100209
AA Change: L2207R
PolyPhen 2
Score 0.974 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000097783
Gene: ENSMUSG00000045350
AA Change: L2207R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
21 |
N/A |
INTRINSIC |
|
Blast:FBG
|
44 |
222 |
4e-48 |
BLAST |
|
coiled coil region
|
292 |
340 |
N/A |
INTRINSIC |
|
low complexity region
|
423 |
443 |
N/A |
INTRINSIC |
|
low complexity region
|
446 |
458 |
N/A |
INTRINSIC |
|
low complexity region
|
632 |
644 |
N/A |
INTRINSIC |
|
low complexity region
|
702 |
713 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
743 |
1156 |
1.05e-58 |
PROSPERO |
|
internal_repeat_1
|
833 |
1270 |
7.71e-59 |
PROSPERO |
|
low complexity region
|
1271 |
1285 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1323 |
N/A |
INTRINSIC |
|
low complexity region
|
1327 |
1338 |
N/A |
INTRINSIC |
|
low complexity region
|
1347 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1365 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1384 |
1395 |
N/A |
INTRINSIC |
|
low complexity region
|
1403 |
1414 |
N/A |
INTRINSIC |
|
low complexity region
|
1423 |
1437 |
N/A |
INTRINSIC |
|
low complexity region
|
1441 |
1452 |
N/A |
INTRINSIC |
|
low complexity region
|
1460 |
1471 |
N/A |
INTRINSIC |
|
low complexity region
|
1479 |
1490 |
N/A |
INTRINSIC |
|
low complexity region
|
1498 |
1509 |
N/A |
INTRINSIC |
|
low complexity region
|
1518 |
1532 |
N/A |
INTRINSIC |
|
low complexity region
|
1536 |
1547 |
N/A |
INTRINSIC |
|
low complexity region
|
1555 |
1566 |
N/A |
INTRINSIC |
|
low complexity region
|
1574 |
1585 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1586 |
1981 |
7.71e-59 |
PROSPERO |
|
internal_repeat_2
|
1737 |
2197 |
1.05e-58 |
PROSPERO |
|
low complexity region
|
2367 |
2378 |
N/A |
INTRINSIC |
|
low complexity region
|
2549 |
2564 |
N/A |
INTRINSIC |
|
low complexity region
|
2644 |
2655 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000104255
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000177831
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180309
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.2%
- 20x: 94.9%
|
| Validation Efficiency |
99% (95/96) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acaa1a |
C |
A |
9: 119,170,630 (GRCm39) |
S17* |
probably null |
Het |
| Adamts16 |
T |
A |
13: 70,984,322 (GRCm39) |
S114C |
probably damaging |
Het |
| Agpat5 |
T |
C |
8: 18,896,724 (GRCm39) |
V50A |
probably benign |
Het |
| Agrn |
T |
C |
4: 156,263,891 (GRCm39) |
N124S |
probably benign |
Het |
| Ak8 |
T |
C |
2: 28,625,638 (GRCm39) |
I227T |
probably benign |
Het |
| Akap6 |
A |
G |
12: 53,188,808 (GRCm39) |
E2074G |
probably damaging |
Het |
| Apc |
T |
A |
18: 34,445,265 (GRCm39) |
S702R |
probably damaging |
Het |
| Ascc3 |
T |
C |
10: 50,596,769 (GRCm39) |
I1233T |
probably damaging |
Het |
| Asphd2 |
A |
T |
5: 112,533,698 (GRCm39) |
F318I |
probably damaging |
Het |
| Bltp1 |
G |
A |
3: 36,962,377 (GRCm39) |
A493T |
probably damaging |
Het |
| Bnc2 |
T |
C |
4: 84,211,380 (GRCm39) |
T397A |
probably benign |
Het |
| Bpifb4 |
C |
T |
2: 153,799,054 (GRCm39) |
T528I |
probably damaging |
Het |
| Brinp3 |
A |
G |
1: 146,777,323 (GRCm39) |
E590G |
probably damaging |
Het |
| Ccdc149 |
A |
G |
5: 52,542,477 (GRCm39) |
S372P |
probably benign |
Het |
| Cdhr2 |
A |
G |
13: 54,874,589 (GRCm39) |
H887R |
probably benign |
Het |
| Clcn6 |
C |
T |
4: 148,101,957 (GRCm39) |
V376I |
probably benign |
Het |
| Cntln |
T |
G |
4: 85,033,591 (GRCm39) |
C1305W |
probably damaging |
Het |
| Cspg4 |
A |
G |
9: 56,799,928 (GRCm39) |
D1564G |
probably benign |
Het |
| Cux1 |
A |
T |
5: 136,338,646 (GRCm39) |
S582T |
probably damaging |
Het |
| Cwh43 |
G |
A |
5: 73,569,248 (GRCm39) |
A97T |
possibly damaging |
Het |
| Dsc1 |
A |
T |
18: 20,219,826 (GRCm39) |
F781L |
probably damaging |
Het |
| Dsc3 |
G |
T |
18: 20,099,348 (GRCm39) |
H723N |
probably benign |
Het |
| Ear10 |
A |
T |
14: 44,160,512 (GRCm39) |
V105D |
probably damaging |
Het |
| Ecel1 |
A |
G |
1: 87,077,231 (GRCm39) |
V659A |
possibly damaging |
Het |
| Eogt |
A |
T |
6: 97,097,155 (GRCm39) |
F316I |
probably damaging |
Het |
| Etaa1 |
T |
C |
11: 17,897,188 (GRCm39) |
N310D |
possibly damaging |
Het |
| Exoc3l2 |
G |
A |
7: 19,203,633 (GRCm39) |
R75Q |
possibly damaging |
Het |
| Fam187b |
T |
C |
7: 30,677,024 (GRCm39) |
Y178H |
probably damaging |
Het |
| Fat1 |
A |
T |
8: 45,486,532 (GRCm39) |
Q3362L |
probably damaging |
Het |
| Fat3 |
A |
T |
9: 15,849,694 (GRCm39) |
S3903T |
probably damaging |
Het |
| Fsip2 |
G |
A |
2: 82,823,028 (GRCm39) |
V6254I |
possibly damaging |
Het |
| Gabra5 |
T |
C |
7: 57,063,528 (GRCm39) |
T299A |
probably damaging |
Het |
| Gbp11 |
T |
C |
5: 105,475,464 (GRCm39) |
T295A |
probably benign |
Het |
| Glcci1 |
C |
T |
6: 8,573,203 (GRCm39) |
Q44* |
probably null |
Het |
| Gpc5 |
A |
T |
14: 115,636,612 (GRCm39) |
T432S |
probably benign |
Het |
| Grhl1 |
G |
A |
12: 24,634,857 (GRCm39) |
E228K |
probably damaging |
Het |
| Hyal5 |
T |
C |
6: 24,891,708 (GRCm39) |
|
probably null |
Het |
| Idh2 |
TCCCAGG |
T |
7: 79,748,079 (GRCm39) |
|
probably benign |
Het |
| Ints9 |
A |
G |
14: 65,230,456 (GRCm39) |
I128V |
probably damaging |
Het |
| Kcnt2 |
A |
T |
1: 140,302,850 (GRCm39) |
N130I |
probably damaging |
Het |
| Krba1 |
T |
C |
6: 48,391,062 (GRCm39) |
V717A |
probably benign |
Het |
| Lrp12 |
T |
A |
15: 39,741,584 (GRCm39) |
D377V |
probably damaging |
Het |
| Magi1 |
G |
T |
6: 93,920,210 (GRCm39) |
D135E |
possibly damaging |
Het |
| Map10 |
T |
A |
8: 126,397,984 (GRCm39) |
L459Q |
probably damaging |
Het |
| Mitf |
A |
G |
6: 97,980,873 (GRCm39) |
D238G |
possibly damaging |
Het |
| Ms4a19 |
C |
T |
19: 11,119,765 (GRCm39) |
G14D |
probably damaging |
Het |
| Mylk |
G |
T |
16: 34,742,341 (GRCm39) |
R951L |
probably benign |
Het |
| Nacad |
T |
A |
11: 6,549,235 (GRCm39) |
D1272V |
probably damaging |
Het |
| Nacad |
T |
A |
11: 6,550,165 (GRCm39) |
K1009* |
probably null |
Het |
| Ncor1 |
T |
C |
11: 62,264,124 (GRCm39) |
D786G |
probably benign |
Het |
| Oas2 |
G |
A |
5: 120,886,603 (GRCm39) |
R188C |
probably benign |
Het |
| Odf2l |
A |
G |
3: 144,841,479 (GRCm39) |
I300V |
probably benign |
Het |
| Or1j10 |
T |
A |
2: 36,267,208 (GRCm39) |
V140D |
possibly damaging |
Het |
| Or51b17 |
A |
T |
7: 103,542,342 (GRCm39) |
L200* |
probably null |
Het |
| Or51v8 |
A |
G |
7: 103,320,163 (GRCm39) |
I25T |
possibly damaging |
Het |
| Or5p60 |
A |
G |
7: 107,723,637 (GRCm39) |
S278P |
probably damaging |
Het |
| Or9i1 |
A |
G |
19: 13,839,186 (GRCm39) |
T10A |
probably benign |
Het |
| Pes1 |
T |
A |
11: 3,928,865 (GRCm39) |
D574E |
probably benign |
Het |
| Phf20 |
C |
T |
2: 156,136,130 (GRCm39) |
R650C |
possibly damaging |
Het |
| Pias4 |
G |
A |
10: 80,993,098 (GRCm39) |
T248I |
probably damaging |
Het |
| Pkhd1 |
T |
C |
1: 20,282,175 (GRCm39) |
T2889A |
probably benign |
Het |
| Plcxd1 |
C |
A |
5: 110,250,033 (GRCm39) |
|
probably null |
Het |
| Plekha7 |
A |
G |
7: 115,776,133 (GRCm39) |
F194L |
probably damaging |
Het |
| Plxnb2 |
T |
C |
15: 89,041,973 (GRCm39) |
N1642S |
possibly damaging |
Het |
| Pnpla7 |
A |
T |
2: 24,901,576 (GRCm39) |
D534V |
probably damaging |
Het |
| Ppp2r5c |
A |
T |
12: 110,521,313 (GRCm39) |
S279C |
probably damaging |
Het |
| Ptprq |
T |
A |
10: 107,544,529 (GRCm39) |
T334S |
probably damaging |
Het |
| Rab39 |
T |
C |
9: 53,597,821 (GRCm39) |
D148G |
probably benign |
Het |
| Reep3 |
A |
T |
10: 66,870,432 (GRCm39) |
F121L |
probably benign |
Het |
| Reln |
G |
T |
5: 22,106,661 (GRCm39) |
C3236* |
probably null |
Het |
| Rrp8 |
C |
T |
7: 105,384,016 (GRCm39) |
C162Y |
probably damaging |
Het |
| Scrib |
C |
A |
15: 75,936,835 (GRCm39) |
Q399H |
possibly damaging |
Het |
| Sertad1 |
T |
A |
7: 27,189,224 (GRCm39) |
Y182N |
possibly damaging |
Het |
| Sfrp5 |
A |
G |
19: 42,190,263 (GRCm39) |
V63A |
possibly damaging |
Het |
| Shoc1 |
T |
C |
4: 59,069,317 (GRCm39) |
D703G |
probably benign |
Het |
| Slc46a1 |
T |
C |
11: 78,357,985 (GRCm39) |
M346T |
probably benign |
Het |
| Sycp2 |
A |
G |
2: 178,005,209 (GRCm39) |
L886S |
probably damaging |
Het |
| Teddm1b |
A |
T |
1: 153,750,505 (GRCm39) |
I105F |
probably benign |
Het |
| Thumpd1 |
A |
T |
7: 119,319,828 (GRCm39) |
I46N |
possibly damaging |
Het |
| Tmod4 |
A |
G |
3: 95,035,164 (GRCm39) |
N223S |
probably damaging |
Het |
| Tnfrsf10b |
G |
C |
14: 70,010,850 (GRCm39) |
C85S |
probably damaging |
Het |
| Tox |
T |
C |
4: 6,697,439 (GRCm39) |
T455A |
probably benign |
Het |
| Tox |
T |
C |
4: 6,741,536 (GRCm39) |
Q148R |
probably benign |
Het |
| Trp53bp1 |
A |
C |
2: 121,100,426 (GRCm39) |
S109R |
probably damaging |
Het |
| Tshz2 |
A |
T |
2: 169,726,888 (GRCm39) |
T26S |
probably benign |
Het |
| Tubb4a |
T |
A |
17: 57,388,016 (GRCm39) |
N337Y |
probably damaging |
Het |
| Tubb6 |
T |
A |
18: 67,534,458 (GRCm39) |
V119E |
probably damaging |
Het |
| Unk |
C |
T |
11: 115,945,772 (GRCm39) |
T481I |
probably benign |
Het |
| Vmn2r112 |
C |
T |
17: 22,820,259 (GRCm39) |
T44I |
probably benign |
Het |
| Vstm5 |
G |
A |
9: 15,168,829 (GRCm39) |
G131D |
probably damaging |
Het |
| Wscd1 |
T |
C |
11: 71,650,709 (GRCm39) |
L12P |
probably damaging |
Het |
| Zfp369 |
T |
A |
13: 65,444,044 (GRCm39) |
S396T |
possibly damaging |
Het |
| Zfp932 |
T |
A |
5: 110,157,209 (GRCm39) |
C302* |
probably null |
Het |
| Zfp972 |
A |
T |
2: 177,548,728 (GRCm39) |
|
probably null |
Het |
| Zfyve21 |
C |
A |
12: 111,794,028 (GRCm39) |
A212E |
probably benign |
Het |
|
| Other mutations in Fam186a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00588:Fam186a
|
APN |
15 |
99,825,572 (GRCm39) |
splice site |
probably benign |
|
|
IGL03047:Fam186a
|
UTSW |
15 |
99,843,589 (GRCm39) |
missense |
unknown |
|
|
R0172:Fam186a
|
UTSW |
15 |
99,852,768 (GRCm39) |
missense |
unknown |
|
|
R0194:Fam186a
|
UTSW |
15 |
99,839,644 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0381:Fam186a
|
UTSW |
15 |
99,840,055 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0799:Fam186a
|
UTSW |
15 |
99,839,893 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1295:Fam186a
|
UTSW |
15 |
99,837,670 (GRCm39) |
splice site |
probably benign |
|
|
R1366:Fam186a
|
UTSW |
15 |
99,841,270 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1519:Fam186a
|
UTSW |
15 |
99,845,536 (GRCm39) |
missense |
unknown |
|
|
R1592:Fam186a
|
UTSW |
15 |
99,838,199 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1636:Fam186a
|
UTSW |
15 |
99,839,539 (GRCm39) |
missense |
unknown |
|
|
R1719:Fam186a
|
UTSW |
15 |
99,840,227 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R1759:Fam186a
|
UTSW |
15 |
99,864,762 (GRCm39) |
nonsense |
probably null |
|
|
R1856:Fam186a
|
UTSW |
15 |
99,838,183 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2131:Fam186a
|
UTSW |
15 |
99,831,557 (GRCm39) |
unclassified |
probably benign |
|
|
R2192:Fam186a
|
UTSW |
15 |
99,838,192 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R2239:Fam186a
|
UTSW |
15 |
99,852,745 (GRCm39) |
missense |
unknown |
|
|
R2251:Fam186a
|
UTSW |
15 |
99,842,978 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2902:Fam186a
|
UTSW |
15 |
99,843,049 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3037:Fam186a
|
UTSW |
15 |
99,841,675 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3744:Fam186a
|
UTSW |
15 |
99,845,416 (GRCm39) |
missense |
unknown |
|
|
R4021:Fam186a
|
UTSW |
15 |
99,839,680 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4183:Fam186a
|
UTSW |
15 |
99,831,566 (GRCm39) |
unclassified |
probably benign |
|
|
R4238:Fam186a
|
UTSW |
15 |
99,841,523 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4667:Fam186a
|
UTSW |
15 |
99,842,413 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4817:Fam186a
|
UTSW |
15 |
99,831,419 (GRCm39) |
unclassified |
probably benign |
|
|
R4835:Fam186a
|
UTSW |
15 |
99,843,689 (GRCm39) |
missense |
unknown |
|
|
R4837:Fam186a
|
UTSW |
15 |
99,838,678 (GRCm39) |
missense |
unknown |
|
|
R4897:Fam186a
|
UTSW |
15 |
99,843,158 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4902:Fam186a
|
UTSW |
15 |
99,844,723 (GRCm39) |
missense |
unknown |
|
|
R4950:Fam186a
|
UTSW |
15 |
99,839,534 (GRCm39) |
missense |
unknown |
|
|
R4995:Fam186a
|
UTSW |
15 |
99,842,980 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5062:Fam186a
|
UTSW |
15 |
99,842,527 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5124:Fam186a
|
UTSW |
15 |
99,840,977 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5133:Fam186a
|
UTSW |
15 |
99,853,374 (GRCm39) |
missense |
unknown |
|
|
R5424:Fam186a
|
UTSW |
15 |
99,843,644 (GRCm39) |
missense |
unknown |
|
|
R5624:Fam186a
|
UTSW |
15 |
99,839,628 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5628:Fam186a
|
UTSW |
15 |
99,839,628 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5637:Fam186a
|
UTSW |
15 |
99,839,628 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5639:Fam186a
|
UTSW |
15 |
99,844,931 (GRCm39) |
missense |
unknown |
|
|
R5652:Fam186a
|
UTSW |
15 |
99,843,253 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5673:Fam186a
|
UTSW |
15 |
99,839,628 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5799:Fam186a
|
UTSW |
15 |
99,864,705 (GRCm39) |
nonsense |
probably null |
|
|
R5965:Fam186a
|
UTSW |
15 |
99,842,978 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6044:Fam186a
|
UTSW |
15 |
99,839,878 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6077:Fam186a
|
UTSW |
15 |
99,840,584 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6120:Fam186a
|
UTSW |
15 |
99,838,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6185:Fam186a
|
UTSW |
15 |
99,845,530 (GRCm39) |
missense |
unknown |
|
|
R6186:Fam186a
|
UTSW |
15 |
99,845,206 (GRCm39) |
missense |
unknown |
|
|
R6242:Fam186a
|
UTSW |
15 |
99,837,788 (GRCm39) |
missense |
unknown |
|
|
R6368:Fam186a
|
UTSW |
15 |
99,841,198 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6369:Fam186a
|
UTSW |
15 |
99,845,212 (GRCm39) |
missense |
unknown |
|
|
R6559:Fam186a
|
UTSW |
15 |
99,842,356 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6855:Fam186a
|
UTSW |
15 |
99,852,756 (GRCm39) |
missense |
unknown |
|
|
R6867:Fam186a
|
UTSW |
15 |
99,843,731 (GRCm39) |
missense |
unknown |
|
|
R6957:Fam186a
|
UTSW |
15 |
99,844,357 (GRCm39) |
missense |
unknown |
|
|
R6961:Fam186a
|
UTSW |
15 |
99,838,082 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6994:Fam186a
|
UTSW |
15 |
99,840,347 (GRCm39) |
missense |
probably benign |
0.35 |
|
R6996:Fam186a
|
UTSW |
15 |
99,853,374 (GRCm39) |
missense |
unknown |
|
|
R7062:Fam186a
|
UTSW |
15 |
99,831,521 (GRCm39) |
unclassified |
probably benign |
|
|
R7064:Fam186a
|
UTSW |
15 |
99,839,557 (GRCm39) |
missense |
unknown |
|
|
R7173:Fam186a
|
UTSW |
15 |
99,843,531 (GRCm39) |
missense |
unknown |
|
|
R7244:Fam186a
|
UTSW |
15 |
99,844,273 (GRCm39) |
missense |
unknown |
|
|
R7270:Fam186a
|
UTSW |
15 |
99,842,033 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7410:Fam186a
|
UTSW |
15 |
99,844,826 (GRCm39) |
nonsense |
probably null |
|
|
R7437:Fam186a
|
UTSW |
15 |
99,840,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7475:Fam186a
|
UTSW |
15 |
99,845,395 (GRCm39) |
missense |
unknown |
|
|
R7487:Fam186a
|
UTSW |
15 |
99,840,017 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7526:Fam186a
|
UTSW |
15 |
99,839,796 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7650:Fam186a
|
UTSW |
15 |
99,837,788 (GRCm39) |
missense |
unknown |
|
|
R7658:Fam186a
|
UTSW |
15 |
99,837,725 (GRCm39) |
missense |
unknown |
|
|
R7663:Fam186a
|
UTSW |
15 |
99,842,950 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7703:Fam186a
|
UTSW |
15 |
99,852,678 (GRCm39) |
missense |
unknown |
|
|
R7814:Fam186a
|
UTSW |
15 |
99,842,545 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7958:Fam186a
|
UTSW |
15 |
99,841,189 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7970:Fam186a
|
UTSW |
15 |
99,831,467 (GRCm39) |
missense |
unknown |
|
|
R8076:Fam186a
|
UTSW |
15 |
99,841,351 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8087:Fam186a
|
UTSW |
15 |
99,839,725 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8130:Fam186a
|
UTSW |
15 |
99,841,914 (GRCm39) |
frame shift |
probably null |
|
|
R8239:Fam186a
|
UTSW |
15 |
99,839,191 (GRCm39) |
missense |
unknown |
|
|
R8246:Fam186a
|
UTSW |
15 |
99,838,428 (GRCm39) |
missense |
unknown |
|
|
R8446:Fam186a
|
UTSW |
15 |
99,845,335 (GRCm39) |
missense |
unknown |
|
|
R8469:Fam186a
|
UTSW |
15 |
99,845,186 (GRCm39) |
missense |
unknown |
|
|
R8676:Fam186a
|
UTSW |
15 |
99,845,023 (GRCm39) |
missense |
unknown |
|
|
R8790:Fam186a
|
UTSW |
15 |
99,841,024 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8808:Fam186a
|
UTSW |
15 |
99,842,604 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8848:Fam186a
|
UTSW |
15 |
99,838,034 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9083:Fam186a
|
UTSW |
15 |
99,843,079 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9106:Fam186a
|
UTSW |
15 |
99,844,107 (GRCm39) |
small deletion |
probably benign |
|
|
R9116:Fam186a
|
UTSW |
15 |
99,840,472 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9156:Fam186a
|
UTSW |
15 |
99,841,159 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R9227:Fam186a
|
UTSW |
15 |
99,853,384 (GRCm39) |
missense |
unknown |
|
|
R9250:Fam186a
|
UTSW |
15 |
99,845,330 (GRCm39) |
missense |
unknown |
|
|
R9282:Fam186a
|
UTSW |
15 |
99,839,879 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9495:Fam186a
|
UTSW |
15 |
99,844,766 (GRCm39) |
missense |
unknown |
|
|
R9514:Fam186a
|
UTSW |
15 |
99,844,766 (GRCm39) |
missense |
unknown |
|
|
R9521:Fam186a
|
UTSW |
15 |
99,841,471 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9553:Fam186a
|
UTSW |
15 |
99,844,561 (GRCm39) |
missense |
unknown |
|
|
R9641:Fam186a
|
UTSW |
15 |
99,838,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9655:Fam186a
|
UTSW |
15 |
99,840,973 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9661:Fam186a
|
UTSW |
15 |
99,842,492 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9673:Fam186a
|
UTSW |
15 |
99,841,024 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9762:Fam186a
|
UTSW |
15 |
99,842,393 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
X0021:Fam186a
|
UTSW |
15 |
99,843,316 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Fam186a
|
UTSW |
15 |
99,843,875 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TAGAGGCGACAGCTGGTTTG -3'
(R):5'- GAAGATTTGCCTCACCCCTGAG -3'
Sequencing Primer
(F):5'- TGGGGATTTGGATAGACTCAGAG -3'
(R):5'- CCCTGGGGATCACTGTCAC -3'
|
| Posted On |
2018-04-27 |
Incidental Mutation