Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01070:Vmn1r64'

51447

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r64

Ensembl Gene

ENSMUSG00000058399

Gene Name

vomeronasal 1 receptor 64

Synonyms

V1rd11

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.053) question?

Stock #

IGL01070

Quality Score

Status

Chromosome

Chromosomal Location

5886579-5887541 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 5886941 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Alanine to Serine at position 201 (A201S)

Ref Sequence

ENSEMBL: ENSMUSP00000077568 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078475]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000078475
AA Change: A201S

PolyPhen 2 Score 0.037 (Sensitivity: 0.94; Specificity: 0.82)

SMART Domains

Protein: ENSMUSP00000077568
Gene: ENSMUSG00000058399
AA Change: A201S

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	296	3.3e-13	PFAM
Pfam:V1R	41	296	1.5e-19	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110038F14Rik	G	A	15: 76,834,475 (GRCm39)	V124I	probably damaging	Het
Adamts5	T	C	16: 85,660,021 (GRCm39)	H757R	probably damaging	Het
Aen	G	A	7: 78,557,050 (GRCm39)	M299I	probably damaging	Het
Akap3	A	T	6: 126,842,842 (GRCm39)	E487V	possibly damaging	Het
Bicd2	T	C	13: 49,531,792 (GRCm39)	S271P	probably damaging	Het
Cfap206	C	T	4: 34,721,562 (GRCm39)	S162N	probably damaging	Het
Cma1	A	G	14: 56,180,154 (GRCm39)	S71P	probably benign	Het
Cspp1	T	C	1: 10,158,370 (GRCm39)	Y494H	probably damaging	Het
Cyp39a1	A	G	17: 43,993,913 (GRCm39)	K191R	probably benign	Het
Efr3a	G	A	15: 65,724,927 (GRCm39)	V507I	probably benign	Het
Fam178b	C	T	1: 36,603,484 (GRCm39)	R489Q	possibly damaging	Het
Kcnj4	A	G	15: 79,368,780 (GRCm39)	L400P	probably benign	Het
Kif27	A	G	13: 58,491,907 (GRCm39)	Y411H	probably damaging	Het
Mstn	A	T	1: 53,101,156 (GRCm39)	I78L	possibly damaging	Het
Nrap	T	C	19: 56,317,516 (GRCm39)	D1377G	probably damaging	Het
Pramel5	T	G	4: 143,997,842 (GRCm39)	Y467S	probably damaging	Het
Prkg1	G	A	19: 30,546,743 (GRCm39)		probably benign	Het
Rbfox1	A	C	16: 7,124,307 (GRCm39)	S219R	possibly damaging	Het
Rfng	T	C	11: 120,674,778 (GRCm39)	N71D	probably damaging	Het
Rp1	T	C	1: 4,415,461 (GRCm39)	I1884V	probably damaging	Het
Rptn	T	A	3: 93,305,483 (GRCm39)	Y939N	possibly damaging	Het
Sart1	A	G	19: 5,433,979 (GRCm39)	V322A	probably benign	Het
Shank3	T	C	15: 89,433,619 (GRCm39)	S1455P	probably damaging	Het
Smc5	T	A	19: 23,208,965 (GRCm39)	R703W	possibly damaging	Het
Sptan1	G	A	2: 29,904,185 (GRCm39)		probably null	Het
Tecta	T	C	9: 42,306,299 (GRCm39)	D43G	probably damaging	Het
Tmem67	A	T	4: 12,054,750 (GRCm39)	M685K	probably benign	Het
Trac	A	G	14: 54,458,223 (GRCm39)	T82A	probably benign	Het
Trank1	A	G	9: 111,195,861 (GRCm39)	N1295S	probably damaging	Het
Ttc36	T	C	9: 44,712,887 (GRCm39)		probably null	Het
Utp18	A	T	11: 93,760,674 (GRCm39)	S384T	possibly damaging	Het
Vmn2r26	A	T	6: 124,038,566 (GRCm39)	I714F	probably benign	Het
Vps54	T	A	11: 21,262,268 (GRCm39)	V626D	probably damaging	Het
Wapl	T	C	14: 34,467,579 (GRCm39)		probably benign	Het
Yars2	C	T	16: 16,124,406 (GRCm39)	R338*	probably null	Het

Other mutations in Vmn1r64

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Vmn1r64	APN	7	5,886,827 (GRCm39)	missense	probably damaging	0.98
IGL01817:Vmn1r64	APN	7	5,887,222 (GRCm39)	missense	probably damaging	1.00
IGL02026:Vmn1r64	APN	7	5,886,649 (GRCm39)	missense	possibly damaging	0.84
IGL02657:Vmn1r64	APN	7	5,886,727 (GRCm39)	missense	probably benign	0.33
IGL03352:Vmn1r64	APN	7	5,887,070 (GRCm39)	missense	probably benign	0.12
R0200:Vmn1r64	UTSW	7	5,886,817 (GRCm39)	missense	probably benign	0.38
R0540:Vmn1r64	UTSW	7	5,887,096 (GRCm39)	missense	probably damaging	1.00
R0655:Vmn1r64	UTSW	7	5,887,207 (GRCm39)	missense	probably benign	0.25
R1212:Vmn1r64	UTSW	7	5,887,210 (GRCm39)	missense	probably damaging	1.00
R1579:Vmn1r64	UTSW	7	5,886,803 (GRCm39)	missense	probably damaging	1.00
R2034:Vmn1r64	UTSW	7	5,886,988 (GRCm39)	missense	probably benign	0.09
R2221:Vmn1r64	UTSW	7	5,887,448 (GRCm39)	missense	probably benign	0.00
R2240:Vmn1r64	UTSW	7	5,887,369 (GRCm39)	nonsense	probably null
R2305:Vmn1r64	UTSW	7	5,887,535 (GRCm39)	missense	probably benign	0.04
R3019:Vmn1r64	UTSW	7	5,887,226 (GRCm39)	missense	probably damaging	1.00
R4256:Vmn1r64	UTSW	7	5,886,895 (GRCm39)	missense	probably benign	0.05
R4666:Vmn1r64	UTSW	7	5,887,357 (GRCm39)	missense	probably damaging	0.99
R4996:Vmn1r64	UTSW	7	5,887,052 (GRCm39)	missense	probably benign	0.03
R5682:Vmn1r64	UTSW	7	5,886,622 (GRCm39)	missense	possibly damaging	0.79
R5730:Vmn1r64	UTSW	7	5,887,522 (GRCm39)	missense	probably benign	0.01
R7397:Vmn1r64	UTSW	7	5,887,013 (GRCm39)	missense	possibly damaging	0.87
R9697:Vmn1r64	UTSW	7	5,886,859 (GRCm39)	missense	probably benign	0.04
X0063:Vmn1r64	UTSW	7	5,887,349 (GRCm39)	missense	probably benign	0.00

Posted On

2013-06-21