Incidental Mutation 'R6376:Apc2'
| ID |
514986 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Apc2
|
| Ensembl Gene |
ENSMUSG00000020135 |
| Gene Name |
APC regulator of WNT signaling pathway 2 |
| Synonyms |
APCL |
| MMRRC Submission |
044526-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.172)
|
| Stock # |
R6376 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
80131811-80154097 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 80148488 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 1152
(C1152S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000020349
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020349]
[ENSMUST00000105359]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000020349
AA Change: C1152S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000020349
Gene: ENSMUSG00000020135
AA Change: C1152S
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:1DEB|B
|
4 |
57 |
9e-17 |
PDB |
|
Pfam:Suppressor_APC
|
123 |
205 |
1.3e-28 |
PFAM |
|
coiled coil region
|
214 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
242 |
261 |
N/A |
INTRINSIC |
|
ARM
|
300 |
355 |
2.95e0 |
SMART |
|
ARM
|
417 |
468 |
2.22e-2 |
SMART |
|
ARM
|
470 |
511 |
3.22e0 |
SMART |
|
ARM
|
513 |
555 |
3.56e-1 |
SMART |
|
ARM
|
557 |
602 |
2.1e1 |
SMART |
|
ARM
|
607 |
647 |
1.82e-7 |
SMART |
|
Blast:ARM
|
649 |
689 |
6e-18 |
BLAST |
|
low complexity region
|
772 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
844 |
N/A |
INTRINSIC |
|
low complexity region
|
859 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
971 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
1057 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1087 |
1103 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1134 |
1159 |
4.4e-9 |
PFAM |
|
low complexity region
|
1197 |
1208 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1244 |
1269 |
4.1e-8 |
PFAM |
|
Pfam:SAMP
|
1323 |
1343 |
2.1e-10 |
PFAM |
|
Pfam:APC_crr
|
1369 |
1394 |
5.8e-8 |
PFAM |
|
low complexity region
|
1500 |
1516 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1540 |
1565 |
5.7e-8 |
PFAM |
|
Pfam:SAMP
|
1594 |
1613 |
8.8e-11 |
PFAM |
|
low complexity region
|
1673 |
1699 |
N/A |
INTRINSIC |
|
Pfam:APC_basic
|
1757 |
2093 |
1.1e-142 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105359
AA Change: C1181S
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000100996
Gene: ENSMUSG00000020135
AA Change: C1181S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:APC_N_CC
|
30 |
81 |
2.7e-34 |
PFAM |
|
Pfam:Suppressor_APC
|
148 |
228 |
1.4e-27 |
PFAM |
|
coiled coil region
|
238 |
260 |
N/A |
INTRINSIC |
|
low complexity region
|
266 |
285 |
N/A |
INTRINSIC |
|
ARM
|
324 |
379 |
2.95e0 |
SMART |
|
ARM
|
446 |
497 |
2.22e-2 |
SMART |
|
ARM
|
499 |
540 |
3.22e0 |
SMART |
|
ARM
|
542 |
584 |
3.56e-1 |
SMART |
|
ARM
|
586 |
631 |
2.1e1 |
SMART |
|
ARM
|
636 |
676 |
1.82e-7 |
SMART |
|
Blast:ARM
|
678 |
718 |
6e-18 |
BLAST |
|
Pfam:Arm_APC_u3
|
719 |
977 |
1.1e-26 |
PFAM |
|
low complexity region
|
1000 |
1009 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1098 |
N/A |
INTRINSIC |
|
low complexity region
|
1116 |
1132 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1164 |
1187 |
9.3e-8 |
PFAM |
|
low complexity region
|
1226 |
1237 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1274 |
1297 |
7.9e-10 |
PFAM |
|
Pfam:APC_crr
|
1399 |
1423 |
1.3e-9 |
PFAM |
|
low complexity region
|
1529 |
1545 |
N/A |
INTRINSIC |
|
low complexity region
|
1585 |
1603 |
N/A |
INTRINSIC |
|
Pfam:SAMP
|
1624 |
1642 |
1.3e-11 |
PFAM |
|
low complexity region
|
1702 |
1728 |
N/A |
INTRINSIC |
|
Pfam:APC_basic
|
1786 |
2122 |
1.3e-122 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.4%
- 20x: 97.8%
|
| Validation Efficiency |
100% (81/81) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele display gradual postnatal growth retardation, abnormal lamination of the cerebral cortex, hippocampus, olfactory bulb and cerebellum, impaired neuronal migration and impaired coordination. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930550C14Rik |
A |
T |
9: 53,339,456 (GRCm39) |
E106D |
probably damaging |
Het |
| A830018L16Rik |
A |
T |
1: 11,868,718 (GRCm39) |
N333Y |
probably damaging |
Het |
| Abca4 |
T |
A |
3: 121,917,309 (GRCm39) |
M1007K |
possibly damaging |
Het |
| Accsl |
T |
A |
2: 93,687,343 (GRCm39) |
I495F |
probably damaging |
Het |
| Acsl3 |
T |
C |
1: 78,674,182 (GRCm39) |
S373P |
possibly damaging |
Het |
| Adam7 |
A |
G |
14: 68,742,546 (GRCm39) |
I689T |
possibly damaging |
Het |
| Akap11 |
G |
A |
14: 78,752,336 (GRCm39) |
T179I |
probably damaging |
Het |
| Ankmy1 |
T |
C |
1: 92,816,187 (GRCm39) |
K309R |
possibly damaging |
Het |
| Apaf1 |
A |
T |
10: 90,859,673 (GRCm39) |
I824N |
probably damaging |
Het |
| Arhgap17 |
C |
A |
7: 122,899,727 (GRCm39) |
W409L |
probably damaging |
Het |
| Arhgef15 |
T |
C |
11: 68,845,796 (GRCm39) |
I19V |
unknown |
Het |
| Arnt |
C |
A |
3: 95,397,936 (GRCm39) |
P573H |
probably damaging |
Het |
| Arvcf |
G |
A |
16: 18,223,882 (GRCm39) |
G932R |
probably damaging |
Het |
| Atg4a-ps |
C |
T |
3: 103,553,044 (GRCm39) |
W99* |
probably null |
Het |
| Atp13a5 |
T |
A |
16: 29,056,004 (GRCm39) |
D1052V |
probably benign |
Het |
| Atp2b4 |
T |
C |
1: 133,642,797 (GRCm39) |
T1103A |
probably damaging |
Het |
| B4galnt4 |
C |
A |
7: 140,647,335 (GRCm39) |
Q362K |
possibly damaging |
Het |
| Cd320 |
T |
A |
17: 34,066,491 (GRCm39) |
N90K |
probably benign |
Het |
| Cep170b |
A |
T |
12: 112,698,502 (GRCm39) |
I87F |
probably damaging |
Het |
| Coq3 |
T |
G |
4: 21,900,486 (GRCm39) |
C238G |
probably benign |
Het |
| Cpa5 |
A |
T |
6: 30,614,044 (GRCm39) |
Q62L |
probably benign |
Het |
| Ctsg |
A |
T |
14: 56,339,110 (GRCm39) |
C49* |
probably null |
Het |
| Cul9 |
T |
C |
17: 46,819,489 (GRCm39) |
T2000A |
probably damaging |
Het |
| Dedd |
C |
T |
1: 171,167,790 (GRCm39) |
P155S |
probably benign |
Het |
| Dnah1 |
A |
G |
14: 30,997,565 (GRCm39) |
S2598P |
probably damaging |
Het |
| Dnah14 |
C |
T |
1: 181,433,459 (GRCm39) |
P379S |
possibly damaging |
Het |
| Dync2h1 |
A |
T |
9: 7,165,703 (GRCm39) |
S519R |
probably benign |
Het |
| Eea1 |
A |
G |
10: 95,874,660 (GRCm39) |
S1192G |
probably benign |
Het |
| Eif5b |
T |
C |
1: 38,084,760 (GRCm39) |
I869T |
probably damaging |
Het |
| Elavl4 |
C |
A |
4: 110,112,651 (GRCm39) |
|
probably benign |
Het |
| Eml2 |
G |
A |
7: 18,935,088 (GRCm39) |
V432I |
probably damaging |
Het |
| Ets2 |
G |
A |
16: 95,520,037 (GRCm39) |
R421H |
probably damaging |
Het |
| Exoc3l2 |
G |
A |
7: 19,203,635 (GRCm39) |
A76T |
possibly damaging |
Het |
| Fam89b |
T |
C |
19: 5,778,757 (GRCm39) |
Y144C |
probably damaging |
Het |
| Greb1 |
T |
C |
12: 16,749,580 (GRCm39) |
E1082G |
probably damaging |
Het |
| Gtf3a |
A |
T |
5: 146,890,798 (GRCm39) |
|
probably null |
Het |
| Hoxc12 |
C |
A |
15: 102,845,524 (GRCm39) |
F79L |
possibly damaging |
Het |
| Hspb8 |
G |
T |
5: 116,547,491 (GRCm39) |
L164I |
probably damaging |
Het |
| Ina |
C |
T |
19: 47,003,564 (GRCm39) |
A124V |
probably benign |
Het |
| Inhbb |
T |
A |
1: 119,345,411 (GRCm39) |
I293F |
probably damaging |
Het |
| Itpr3 |
A |
G |
17: 27,314,449 (GRCm39) |
Y633C |
possibly damaging |
Het |
| Jag2 |
C |
T |
12: 112,872,949 (GRCm39) |
V1102I |
probably benign |
Het |
| Kalrn |
A |
T |
16: 33,796,361 (GRCm39) |
F1138Y |
probably benign |
Het |
| Large2 |
T |
A |
2: 92,200,853 (GRCm39) |
|
probably benign |
Het |
| Lats2 |
A |
G |
14: 57,959,966 (GRCm39) |
S177P |
probably benign |
Het |
| Lims2 |
G |
A |
18: 32,087,515 (GRCm39) |
R124H |
possibly damaging |
Het |
| Lrp2 |
T |
A |
2: 69,313,787 (GRCm39) |
T2315S |
probably benign |
Het |
| Lrrc4c |
A |
C |
2: 97,459,391 (GRCm39) |
T6P |
probably benign |
Het |
| Lrrk2 |
T |
C |
15: 91,626,469 (GRCm39) |
L1171S |
possibly damaging |
Het |
| Man2b2 |
A |
T |
5: 36,978,378 (GRCm39) |
M302K |
probably damaging |
Het |
| Mocos |
G |
A |
18: 24,834,542 (GRCm39) |
G860R |
possibly damaging |
Het |
| Mylk3 |
T |
A |
8: 86,085,571 (GRCm39) |
D258V |
possibly damaging |
Het |
| Nkx1-2 |
C |
T |
7: 132,201,240 (GRCm39) |
D6N |
probably damaging |
Het |
| Nrp2 |
A |
G |
1: 62,758,176 (GRCm39) |
N54S |
possibly damaging |
Het |
| Nt5el |
T |
C |
13: 105,256,473 (GRCm39) |
I514T |
possibly damaging |
Het |
| Or2d2 |
A |
G |
7: 106,727,848 (GRCm39) |
F251L |
probably benign |
Het |
| Pacsin1 |
A |
T |
17: 27,926,879 (GRCm39) |
T195S |
probably benign |
Het |
| Pank4 |
T |
C |
4: 155,056,693 (GRCm39) |
|
probably null |
Het |
| Pdgfra |
A |
T |
5: 75,327,180 (GRCm39) |
M126L |
probably benign |
Het |
| Podxl |
T |
A |
6: 31,505,432 (GRCm39) |
T204S |
probably benign |
Het |
| Pole |
G |
A |
5: 110,484,240 (GRCm39) |
D2175N |
probably damaging |
Het |
| Pramel16 |
C |
T |
4: 143,677,267 (GRCm39) |
G104E |
probably benign |
Het |
| Prkdc |
A |
G |
16: 15,587,749 (GRCm39) |
K2545E |
probably benign |
Het |
| Prodh |
T |
C |
16: 17,897,849 (GRCm39) |
I183V |
probably benign |
Het |
| Ptch1 |
T |
C |
13: 63,691,422 (GRCm39) |
D277G |
possibly damaging |
Het |
| Rapgef5 |
G |
A |
12: 117,684,988 (GRCm39) |
V246M |
probably damaging |
Het |
| Rubcnl |
A |
G |
14: 75,269,834 (GRCm39) |
N164S |
probably benign |
Het |
| Samd4 |
A |
T |
14: 47,290,419 (GRCm39) |
L175F |
probably damaging |
Het |
| Scart1 |
G |
A |
7: 139,808,642 (GRCm39) |
G851D |
probably damaging |
Het |
| Scimp |
C |
A |
11: 70,688,893 (GRCm39) |
W41L |
possibly damaging |
Het |
| Scn3a |
T |
A |
2: 65,291,843 (GRCm39) |
K1634N |
possibly damaging |
Het |
| Spta1 |
A |
G |
1: 174,030,888 (GRCm39) |
R957G |
probably benign |
Het |
| Sptlc3 |
T |
A |
2: 139,478,692 (GRCm39) |
N550K |
probably benign |
Het |
| Srebf1 |
T |
C |
11: 60,094,361 (GRCm39) |
N609D |
probably null |
Het |
| Styxl1 |
A |
T |
5: 135,776,664 (GRCm39) |
L164H |
probably benign |
Het |
| Synpo2l |
A |
T |
14: 20,710,702 (GRCm39) |
D865E |
probably damaging |
Het |
| Tnfsf15 |
T |
C |
4: 63,663,267 (GRCm39) |
M19V |
probably damaging |
Het |
| Trappc8 |
G |
C |
18: 20,970,132 (GRCm39) |
R953G |
probably benign |
Het |
| Trav13-1 |
A |
G |
14: 53,782,800 (GRCm39) |
N50S |
probably benign |
Het |
| Trim12a |
T |
C |
7: 103,955,241 (GRCm39) |
K161E |
probably benign |
Het |
| Vipr1 |
C |
A |
9: 121,493,640 (GRCm39) |
N230K |
probably damaging |
Het |
| Xirp1 |
A |
T |
9: 119,847,557 (GRCm39) |
V3E |
probably damaging |
Het |
| Zfp768 |
A |
G |
7: 126,943,892 (GRCm39) |
F82L |
probably benign |
Het |
|
| Other mutations in Apc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01069:Apc2
|
APN |
10 |
80,147,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01154:Apc2
|
APN |
10 |
80,148,903 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01411:Apc2
|
APN |
10 |
80,150,912 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01598:Apc2
|
APN |
10 |
80,148,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01621:Apc2
|
APN |
10 |
80,142,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01720:Apc2
|
APN |
10 |
80,150,333 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01837:Apc2
|
APN |
10 |
80,150,492 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01933:Apc2
|
APN |
10 |
80,147,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02243:Apc2
|
APN |
10 |
80,138,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02292:Apc2
|
APN |
10 |
80,138,258 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02956:Apc2
|
APN |
10 |
80,142,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03081:Apc2
|
APN |
10 |
80,148,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03172:Apc2
|
APN |
10 |
80,149,220 (GRCm39) |
missense |
probably damaging |
0.98 |
|
LCD18:Apc2
|
UTSW |
10 |
80,135,808 (GRCm39) |
intron |
probably benign |
|
|
R0278:Apc2
|
UTSW |
10 |
80,148,647 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0501:Apc2
|
UTSW |
10 |
80,150,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Apc2
|
UTSW |
10 |
80,142,090 (GRCm39) |
nonsense |
probably null |
|
|
R0607:Apc2
|
UTSW |
10 |
80,149,935 (GRCm39) |
missense |
probably benign |
|
|
R0624:Apc2
|
UTSW |
10 |
80,150,417 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0633:Apc2
|
UTSW |
10 |
80,143,289 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0638:Apc2
|
UTSW |
10 |
80,140,801 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0647:Apc2
|
UTSW |
10 |
80,140,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0830:Apc2
|
UTSW |
10 |
80,151,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1071:Apc2
|
UTSW |
10 |
80,147,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1221:Apc2
|
UTSW |
10 |
80,142,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1432:Apc2
|
UTSW |
10 |
80,148,183 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1579:Apc2
|
UTSW |
10 |
80,147,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Apc2
|
UTSW |
10 |
80,137,676 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1700:Apc2
|
UTSW |
10 |
80,148,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1774:Apc2
|
UTSW |
10 |
80,144,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Apc2
|
UTSW |
10 |
80,149,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1908:Apc2
|
UTSW |
10 |
80,150,678 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1915:Apc2
|
UTSW |
10 |
80,151,701 (GRCm39) |
missense |
probably benign |
|
|
R1999:Apc2
|
UTSW |
10 |
80,144,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2050:Apc2
|
UTSW |
10 |
80,143,443 (GRCm39) |
splice site |
probably null |
|
|
R2219:Apc2
|
UTSW |
10 |
80,144,943 (GRCm39) |
missense |
probably benign |
0.41 |
|
R2393:Apc2
|
UTSW |
10 |
80,148,903 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R3862:Apc2
|
UTSW |
10 |
80,143,393 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3900:Apc2
|
UTSW |
10 |
80,131,806 (GRCm39) |
splice site |
probably null |
|
|
R3901:Apc2
|
UTSW |
10 |
80,150,922 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3952:Apc2
|
UTSW |
10 |
80,150,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4009:Apc2
|
UTSW |
10 |
80,149,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4090:Apc2
|
UTSW |
10 |
80,141,378 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4695:Apc2
|
UTSW |
10 |
80,146,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4754:Apc2
|
UTSW |
10 |
80,150,192 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4807:Apc2
|
UTSW |
10 |
80,150,196 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4886:Apc2
|
UTSW |
10 |
80,150,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4964:Apc2
|
UTSW |
10 |
80,149,841 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5056:Apc2
|
UTSW |
10 |
80,137,148 (GRCm39) |
missense |
probably benign |
|
|
R5057:Apc2
|
UTSW |
10 |
80,144,903 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5165:Apc2
|
UTSW |
10 |
80,151,684 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5241:Apc2
|
UTSW |
10 |
80,148,068 (GRCm39) |
missense |
probably benign |
|
|
R5649:Apc2
|
UTSW |
10 |
80,149,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Apc2
|
UTSW |
10 |
80,147,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6124:Apc2
|
UTSW |
10 |
80,142,185 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6218:Apc2
|
UTSW |
10 |
80,142,254 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6490:Apc2
|
UTSW |
10 |
80,149,757 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6572:Apc2
|
UTSW |
10 |
80,147,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6620:Apc2
|
UTSW |
10 |
80,149,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7171:Apc2
|
UTSW |
10 |
80,151,170 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7180:Apc2
|
UTSW |
10 |
80,146,990 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7326:Apc2
|
UTSW |
10 |
80,147,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7340:Apc2
|
UTSW |
10 |
80,149,316 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7378:Apc2
|
UTSW |
10 |
80,147,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7384:Apc2
|
UTSW |
10 |
80,148,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7431:Apc2
|
UTSW |
10 |
80,138,017 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7543:Apc2
|
UTSW |
10 |
80,150,720 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7743:Apc2
|
UTSW |
10 |
80,140,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7759:Apc2
|
UTSW |
10 |
80,147,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8244:Apc2
|
UTSW |
10 |
80,151,166 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8327:Apc2
|
UTSW |
10 |
80,137,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8489:Apc2
|
UTSW |
10 |
80,143,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Apc2
|
UTSW |
10 |
80,150,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8669:Apc2
|
UTSW |
10 |
80,149,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8773:Apc2
|
UTSW |
10 |
80,142,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8920:Apc2
|
UTSW |
10 |
80,149,934 (GRCm39) |
missense |
probably benign |
|
|
R9178:Apc2
|
UTSW |
10 |
80,150,235 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9224:Apc2
|
UTSW |
10 |
80,150,111 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9357:Apc2
|
UTSW |
10 |
80,146,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9394:Apc2
|
UTSW |
10 |
80,145,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9666:Apc2
|
UTSW |
10 |
80,147,183 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9689:Apc2
|
UTSW |
10 |
80,150,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0018:Apc2
|
UTSW |
10 |
80,148,098 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Apc2
|
UTSW |
10 |
80,147,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGACAGCGATTCATCCCTG -3'
(R):5'- TTTCCCACTGCAGGCTGAAC -3'
Sequencing Primer
(F):5'- GCTTGAGGAGGCTGGTCC -3'
(R):5'- CTGAACTGGCTGGTCTCAG -3'
|
| Posted On |
2018-05-04 |
Incidental Mutation