Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01066:Nlrp4g'

51859

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Nlrp4g

Ensembl Gene

ENSMUSG00000079741

Gene Name

NLR family, pyrin domain containing 4G

Synonyms

nalp4g

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.078) question?

Stock #

IGL01066

Quality Score

Status

Chromosome

Chromosomal Location

124117991-124126089 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

C to A at 124349526 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000067621

SMART Domains

Protein: ENSMUSP00000065508
Gene: ENSMUSG00000079741

Domain	Start	End	E-Value	Type
Pfam:NACHT	69	238	1.5e-39	PFAM
Blast:LRR	555	582	9e-10	BLAST
Blast:LRR	610	637	7e-10	BLAST

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000214229

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215276

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215602

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000216416

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000217178

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000217183

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 58 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110038F14Rik	G	A	15: 76,834,475 (GRCm39)	V124I	probably damaging	Het
2300003K06Rik	T	A	11: 99,728,454 (GRCm39)	R130*	probably null	Het
Abca12	T	A	1: 71,392,889 (GRCm39)	R117W	possibly damaging	Het
Agrn	A	G	4: 156,261,800 (GRCm39)	S497P	probably benign	Het
Alpk1	A	T	3: 127,473,874 (GRCm39)	S710T	probably benign	Het
Anapc4	T	A	5: 53,014,551 (GRCm39)	N471K	probably benign	Het
Ano3	A	T	2: 110,491,790 (GRCm39)	M879K	probably null	Het
Apoe	A	G	7: 19,430,525 (GRCm39)	L239P	probably damaging	Het
Ash1l	T	C	3: 88,891,942 (GRCm39)	Y1274H	probably damaging	Het
B3glct	C	T	5: 149,632,890 (GRCm39)	T80I	possibly damaging	Het
Ccdc146	T	C	5: 21,524,540 (GRCm39)	T271A	probably benign	Het
Chd8	T	A	14: 52,455,223 (GRCm39)	N1088I	probably damaging	Het
Csnk1g2	T	C	10: 80,470,481 (GRCm39)		probably benign	Het
Daxx	T	A	17: 34,132,867 (GRCm39)	V627D	probably benign	Het
Dnai7	C	T	6: 145,121,948 (GRCm39)	G624S	probably damaging	Het
Dpy19l3	A	G	7: 35,392,192 (GRCm39)		probably benign	Het
Enc1	A	G	13: 97,381,822 (GRCm39)	I111V	probably benign	Het
Ep400	A	G	5: 110,816,065 (GRCm39)		probably benign	Het
Fig4	T	C	10: 41,161,413 (GRCm39)		probably benign	Het
Fkbp7	A	T	2: 76,503,252 (GRCm39)	L36*	probably null	Het
Fxn	A	T	19: 24,244,662 (GRCm39)		probably benign	Het
Gm10152	C	T	7: 144,316,993 (GRCm39)	P16L	unknown	Het
Hivep2	T	C	10: 14,024,768 (GRCm39)	V2194A	possibly damaging	Het
Hook3	T	G	8: 26,538,326 (GRCm39)	E525A	probably damaging	Het
Icam1	A	G	9: 20,927,401 (GRCm39)		probably null	Het
Ifngr1	C	T	10: 19,484,946 (GRCm39)	T315I	probably damaging	Het
Igsf10	A	G	3: 59,235,203 (GRCm39)		probably null	Het
Irag2	T	C	6: 145,106,681 (GRCm39)	S222P	probably damaging	Het
Krt87	A	G	15: 101,336,266 (GRCm39)		probably null	Het
Lama1	T	A	17: 68,050,321 (GRCm39)	C311S	probably damaging	Het
Lig3	T	A	11: 82,688,141 (GRCm39)	M714K	possibly damaging	Het
Lypd5	C	T	7: 24,052,910 (GRCm39)	T189I	probably benign	Het
Mapk8ip3	C	T	17: 25,120,692 (GRCm39)	G807D	probably benign	Het
Met	T	C	6: 17,535,104 (GRCm39)		probably null	Het
Nlrp6	T	A	7: 140,501,709 (GRCm39)	V62D	possibly damaging	Het
Nme7	A	G	1: 164,172,999 (GRCm39)		probably null	Het
Or2y1f	T	C	11: 49,184,457 (GRCm39)	I103T	possibly damaging	Het
Or5m9	A	G	2: 85,877,602 (GRCm39)	R259G	probably damaging	Het
Or5p79	T	C	7: 108,221,064 (GRCm39)	F15S	probably damaging	Het
Pcnx1	G	A	12: 82,038,795 (GRCm39)	R2020Q	possibly damaging	Het
Pdzd2	T	A	15: 12,402,718 (GRCm39)		probably benign	Het
Pi4ka	A	G	16: 17,166,637 (GRCm39)		probably benign	Het
Pkdrej	T	G	15: 85,700,360 (GRCm39)	I1859L	probably benign	Het
Plcg1	A	T	2: 160,596,318 (GRCm39)	H638L	probably damaging	Het
Polr1b	C	T	2: 128,961,072 (GRCm39)	S677L	probably damaging	Het
Ppef2	A	G	5: 92,382,096 (GRCm39)	L533P	probably damaging	Het
Sh3rf1	T	A	8: 61,782,370 (GRCm39)	W171R	probably damaging	Het
Son	T	C	16: 91,457,024 (GRCm39)		probably benign	Het
Sycp1	A	G	3: 102,827,950 (GRCm39)	S266P	probably damaging	Het
Tedc1	A	G	12: 113,126,770 (GRCm39)	E344G	probably damaging	Het
Tkfc	T	C	19: 10,571,892 (GRCm39)	I381M	probably benign	Het
Tmprss6	T	C	15: 78,326,634 (GRCm39)	D1G	probably null	Het
Ttn	T	C	2: 76,582,770 (GRCm39)	T22708A	probably damaging	Het
Ubtf	T	C	11: 102,199,710 (GRCm39)		probably benign	Het
Vps35l	T	A	7: 118,372,234 (GRCm39)		probably null	Het
Vwc2l	T	C	1: 70,768,070 (GRCm39)	F45L	probably damaging	Het
Xpo7	T	C	14: 70,939,195 (GRCm39)	T154A	probably benign	Het
Yars2	C	T	16: 16,124,406 (GRCm39)	R338*	probably null	Het

Other mutations in Nlrp4g

Allele	Source	Chr	Coord	Type	Predicted Effect
IGL01087:Nlrp4g	APN	9	124,353,858 (GRCm38)	critical splice acceptor site	noncoding transcript
IGL01106:Nlrp4g	APN	9	124,350,452 (GRCm38)	unclassified	noncoding transcript
IGL01938:Nlrp4g	APN	9	124,349,068 (GRCm38)	unclassified	noncoding transcript
IGL02088:Nlrp4g	APN	9	124,350,453 (GRCm38)	unclassified	noncoding transcript
IGL02170:Nlrp4g	APN	9	124,348,980 (GRCm38)	unclassified	noncoding transcript
IGL02582:Nlrp4g	APN	9	124,349,764 (GRCm38)	unclassified	noncoding transcript
IGL02588:Nlrp4g	APN	9	124,348,843 (GRCm38)	unclassified	noncoding transcript
IGL02931:Nlrp4g	APN	9	124,348,940 (GRCm38)	unclassified	noncoding transcript
IGL03111:Nlrp4g	APN	9	124,353,978 (GRCm38)	exon	noncoding transcript
IGL03373:Nlrp4g	APN	9	124,349,853 (GRCm38)	unclassified	noncoding transcript
R0617:Nlrp4g	UTSW	9	124,349,540 (GRCm38)	unclassified	noncoding transcript
R1419:Nlrp4g	UTSW	9	124,349,434 (GRCm38)	unclassified	noncoding transcript
R2060:Nlrp4g	UTSW	9	124,349,693 (GRCm38)	unclassified	noncoding transcript
R2152:Nlrp4g	UTSW	9	124,353,339 (GRCm38)	exon	noncoding transcript
R2356:Nlrp4g	UTSW	9	124,349,306 (GRCm38)	unclassified	noncoding transcript
R2384:Nlrp4g	UTSW	9	124,349,707 (GRCm38)	unclassified	noncoding transcript
R2698:Nlrp4g	UTSW	9	124,349,630 (GRCm38)	unclassified	noncoding transcript
R3878:Nlrp4g	UTSW	9	124,349,362 (GRCm38)	unclassified	noncoding transcript
R4640:Nlrp4g	UTSW	9	124,349,153 (GRCm38)	unclassified	noncoding transcript
R4745:Nlrp4g	UTSW	9	124,349,515 (GRCm38)	unclassified	noncoding transcript
R4754:Nlrp4g	UTSW	9	124,349,788 (GRCm38)	unclassified	noncoding transcript
R4937:Nlrp4g	UTSW	9	124,354,005 (GRCm38)	exon	noncoding transcript
R5024:Nlrp4g	UTSW	9	124,350,155 (GRCm38)	unclassified	noncoding transcript
R5162:Nlrp4g	UTSW	9	124,350,394 (GRCm38)	unclassified	noncoding transcript
R5407:Nlrp4g	UTSW	9	124,349,930 (GRCm38)	unclassified	noncoding transcript
R5521:Nlrp4g	UTSW	9	124,350,020 (GRCm38)	unclassified	noncoding transcript
R8224:Nlrp4g	UTSW	9	124,353,374 (GRCm38)	missense	noncoding transcript
R8259:Nlrp4g	UTSW	9	124,353,392 (GRCm38)	missense	noncoding transcript
Z1088:Nlrp4g	UTSW	9	124,349,201 (GRCm38)	unclassified	noncoding transcript

Posted On

2013-06-21