Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01089:Gm1110'

51896

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm1110

Ensembl Gene

ENSMUSG00000079644

Gene Name

predicted gene 1110

Synonyms

LOC382064

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.069) question?

Stock #

IGL01089

Quality Score

Status

Chromosome

Chromosomal Location

26790863-26834407 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 26793156 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 540 (N540S)

Ref Sequence

ENSEMBL: ENSMUSP00000110916 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000115261]

AlphaFold

F6Y113

Predicted Effect

probably benign
Transcript: ENSMUST00000115261
AA Change: N540S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000110916
Gene: ENSMUSG00000079644
AA Change: N540S

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
Pfam:Glyco_hydro_35	55	368	2e-93	PFAM
Pfam:Glyco_hydro_42	70	229	1e-12	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000214847

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000217197

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Actr8	T	C	14: 29,710,292 (GRCm39)	L353S	probably damaging	Het
Adgrf2	G	A	17: 43,021,049 (GRCm39)	P592S	probably damaging	Het
Aen	G	A	7: 78,557,050 (GRCm39)	M299I	probably damaging	Het
Afap1l2	A	C	19: 56,901,843 (GRCm39)		probably null	Het
Asnsd1	G	A	1: 53,387,436 (GRCm39)	P64S	probably damaging	Het
Bmt2	A	G	6: 13,663,270 (GRCm39)	M76T	probably damaging	Het
Clca3b	A	T	3: 144,529,283 (GRCm39)	V797D	probably benign	Het
Cog2	T	C	8: 125,271,982 (GRCm39)	S499P	probably benign	Het
Cyp27a1	A	T	1: 74,771,097 (GRCm39)	Y94F	possibly damaging	Het
D630045J12Rik	A	G	6: 38,113,898 (GRCm39)	S1765P	probably benign	Het
Fam149a	A	G	8: 45,801,564 (GRCm39)	L519P	possibly damaging	Het
Fam171a2	G	A	11: 102,328,674 (GRCm39)	A695V	possibly damaging	Het
Fat1	T	A	8: 45,470,894 (GRCm39)	V1566E	probably damaging	Het
Flvcr1	T	G	1: 190,745,587 (GRCm39)	N361H	probably damaging	Het
Katnip	A	G	7: 125,394,485 (GRCm39)	E187G	probably damaging	Het
Kcns3	T	A	12: 11,141,572 (GRCm39)	T376S	possibly damaging	Het
Krt32	A	G	11: 99,978,605 (GRCm39)	S150P	probably benign	Het
Liat1	A	G	11: 75,894,163 (GRCm39)	E180G	possibly damaging	Het
Lrtm2	C	T	6: 119,297,753 (GRCm39)	R96Q	possibly damaging	Het
Mctp1	A	G	13: 77,168,917 (GRCm39)	E838G	probably damaging	Het
Mios	T	C	6: 8,234,363 (GRCm39)		probably null	Het
Or1j10	A	T	2: 36,267,178 (GRCm39)	Y130F	probably damaging	Het
Phldb1	T	A	9: 44,619,184 (GRCm39)	K167*	probably null	Het
Pkhd1l1	A	G	15: 44,347,265 (GRCm39)		probably benign	Het
Plaa	A	G	4: 94,462,284 (GRCm39)	V531A	probably benign	Het
Psmb2	A	G	4: 126,577,999 (GRCm39)	Y59C	probably damaging	Het
Ptprg	A	G	14: 12,215,286 (GRCm38)	H1091R	probably damaging	Het
Rbm44	T	A	1: 91,096,419 (GRCm39)	V926D	possibly damaging	Het
Rgma	G	T	7: 73,059,462 (GRCm39)	V189L	possibly damaging	Het
Sbf2	A	T	7: 109,948,169 (GRCm39)	I1227K	probably damaging	Het
Slc8a1	T	C	17: 81,955,710 (GRCm39)	T443A	probably damaging	Het
Slc8a1	A	G	17: 81,696,310 (GRCm39)	V896A	probably damaging	Het
Taf2	T	C	15: 54,879,977 (GRCm39)	M1120V	probably benign	Het
Ugt2b34	C	T	5: 87,054,185 (GRCm39)	V199I	probably benign	Het
Unc5c	C	A	3: 141,523,963 (GRCm39)		probably benign	Het
Usp37	G	A	1: 74,532,205 (GRCm39)	R63*	probably null	Het

Other mutations in Gm1110

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00591:Gm1110	APN	9	26,792,170 (GRCm39)	nonsense	probably null
IGL01631:Gm1110	APN	9	26,809,212 (GRCm39)	critical splice donor site	probably null
IGL02008:Gm1110	APN	9	26,794,526 (GRCm39)	missense	probably benign	0.09
IGL02331:Gm1110	APN	9	26,824,583 (GRCm39)	critical splice donor site	probably null
IGL02335:Gm1110	APN	9	26,793,059 (GRCm39)	missense	probably benign	0.00
IGL02550:Gm1110	APN	9	26,793,130 (GRCm39)	missense	probably benign	0.09
IGL02614:Gm1110	APN	9	26,832,010 (GRCm39)	missense	probably benign	0.11
IGL03409:Gm1110	APN	9	26,807,916 (GRCm39)	missense	probably benign	0.21
PIT4458001:Gm1110	UTSW	9	26,792,124 (GRCm39)	missense	probably benign	0.00
R0189:Gm1110	UTSW	9	26,794,514 (GRCm39)	missense	probably null	0.99
R0271:Gm1110	UTSW	9	26,831,962 (GRCm39)	missense	probably damaging	1.00
R1034:Gm1110	UTSW	9	26,832,646 (GRCm39)	missense	probably damaging	1.00
R1229:Gm1110	UTSW	9	26,793,102 (GRCm39)	missense	probably benign
R1355:Gm1110	UTSW	9	26,795,057 (GRCm39)	missense	probably benign	0.01
R1566:Gm1110	UTSW	9	26,792,166 (GRCm39)	missense	probably damaging	1.00
R1574:Gm1110	UTSW	9	26,792,422 (GRCm39)	splice site	probably benign
R1916:Gm1110	UTSW	9	26,800,934 (GRCm39)	missense	probably damaging	1.00
R2011:Gm1110	UTSW	9	26,805,554 (GRCm39)	missense	probably benign	0.01
R2214:Gm1110	UTSW	9	26,813,786 (GRCm39)	missense	probably benign	0.37
R2567:Gm1110	UTSW	9	26,831,992 (GRCm39)	missense	probably benign
R2967:Gm1110	UTSW	9	26,792,339 (GRCm39)	missense	probably benign	0.05
R4271:Gm1110	UTSW	9	26,806,944 (GRCm39)	critical splice donor site	probably null
R4683:Gm1110	UTSW	9	26,831,890 (GRCm39)	missense	probably damaging	0.99
R4945:Gm1110	UTSW	9	26,831,891 (GRCm39)	missense	possibly damaging	0.46
R5015:Gm1110	UTSW	9	26,793,162 (GRCm39)	missense	probably benign	0.01
R5089:Gm1110	UTSW	9	26,793,683 (GRCm39)	missense	probably damaging	0.96
R5225:Gm1110	UTSW	9	26,813,774 (GRCm39)	missense	probably damaging	1.00
R5239:Gm1110	UTSW	9	26,804,866 (GRCm39)	missense	probably benign	0.00
R5395:Gm1110	UTSW	9	26,800,928 (GRCm39)	missense	probably benign
R5783:Gm1110	UTSW	9	26,793,632 (GRCm39)	missense	probably benign
R6045:Gm1110	UTSW	9	26,794,505 (GRCm39)	critical splice donor site	probably null
R6245:Gm1110	UTSW	9	26,832,043 (GRCm39)	missense	probably benign	0.04
R6357:Gm1110	UTSW	9	26,825,424 (GRCm39)	splice site	probably null
R6863:Gm1110	UTSW	9	26,792,360 (GRCm39)	missense	probably damaging	1.00
R7336:Gm1110	UTSW	9	26,825,653 (GRCm39)	missense	probably damaging	0.99
R7454:Gm1110	UTSW	9	26,831,945 (GRCm39)	missense	probably benign
R7555:Gm1110	UTSW	9	26,804,924 (GRCm39)	missense	probably benign	0.05
R7579:Gm1110	UTSW	9	26,795,122 (GRCm39)	missense	possibly damaging	0.93
R7990:Gm1110	UTSW	9	26,792,137 (GRCm39)	missense	possibly damaging	0.66
R8062:Gm1110	UTSW	9	26,793,117 (GRCm39)	missense	probably damaging	0.99
R8108:Gm1110	UTSW	9	26,831,957 (GRCm39)	missense	probably damaging	1.00
R8323:Gm1110	UTSW	9	26,813,719 (GRCm39)	critical splice donor site	probably null
R8354:Gm1110	UTSW	9	26,794,577 (GRCm39)	missense	probably benign	0.00
R8354:Gm1110	UTSW	9	26,794,576 (GRCm39)	missense	probably benign	0.01
R8454:Gm1110	UTSW	9	26,794,577 (GRCm39)	missense	probably benign	0.00
R8454:Gm1110	UTSW	9	26,794,576 (GRCm39)	missense	probably benign	0.01
R8494:Gm1110	UTSW	9	26,792,154 (GRCm39)	missense	probably benign	0.04
R8978:Gm1110	UTSW	9	26,807,095 (GRCm39)	splice site	probably benign
R9321:Gm1110	UTSW	9	26,831,891 (GRCm39)	missense	probably benign	0.00
R9513:Gm1110	UTSW	9	26,795,083 (GRCm39)	missense	possibly damaging	0.95
R9545:Gm1110	UTSW	9	26,800,977 (GRCm39)	missense	probably benign	0.00
R9758:Gm1110	UTSW	9	26,800,894 (GRCm39)	nonsense	probably null
RF002:Gm1110	UTSW	9	26,831,936 (GRCm39)	missense	probably damaging	1.00
X0063:Gm1110	UTSW	9	26,805,576 (GRCm39)	missense	probably benign	0.01
Z1088:Gm1110	UTSW	9	26,824,606 (GRCm39)	missense	probably benign	0.01

Posted On

2013-06-21