Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01145:Gm5916'

52009

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm5916

Ensembl Gene

ENSMUSG00000091411

Gene Name

predicted gene 5916

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.083) question?

Stock #

IGL01145

Quality Score

Status

Chromosome

Chromosomal Location

36031230-36040075 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 36031998 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glutamic Acid at position 95 (D95E)

Ref Sequence

ENSEMBL: ENSMUSP00000125855 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000168452]

AlphaFold

G5E8W5

Predicted Effect

unknown
Transcript: ENSMUST00000168452
AA Change: D95E

SMART Domains

Protein: ENSMUSP00000125855
Gene: ENSMUSG00000091411
AA Change: D95E

Domain	Start	End	E-Value	Type
signal peptide	1	17	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acan	A	C	7: 78,749,030 (GRCm39)	D1267A	probably damaging	Het
Ankrd44	A	G	1: 54,801,418 (GRCm39)		probably null	Het
Arap3	T	C	18: 38,122,232 (GRCm39)	M619V	probably benign	Het
C8b	A	T	4: 104,637,777 (GRCm39)	Y83F	probably benign	Het
Capn15	A	G	17: 26,182,024 (GRCm39)	V595A	probably damaging	Het
Cbx1	A	T	11: 96,692,392 (GRCm39)	D93V	probably benign	Het
Cyp2c66	G	T	19: 39,159,405 (GRCm39)	E285D	probably benign	Het
Dkk4	T	A	8: 23,115,402 (GRCm39)	V84D	probably damaging	Het
Dnah17	T	A	11: 117,937,999 (GRCm39)	I3343F	possibly damaging	Het
Dus3l	T	C	17: 57,074,627 (GRCm39)		probably benign	Het
Ecpas	A	C	4: 58,811,501 (GRCm39)	D1467E	probably null	Het
Eif6	A	G	2: 155,668,355 (GRCm39)		probably benign	Het
Eya3	A	G	4: 132,437,306 (GRCm39)	I389V	probably damaging	Het
Gucy2d	T	A	7: 98,099,170 (GRCm39)	S329T	probably benign	Het
Hook3	C	T	8: 26,549,372 (GRCm39)	M157I	probably benign	Het
Iapp	C	A	6: 142,249,090 (GRCm39)	R48S	probably damaging	Het
Ints11	A	G	4: 155,969,583 (GRCm39)	Y153C	probably damaging	Het
Layn	G	A	9: 50,985,346 (GRCm39)	T62I	probably benign	Het
Llgl2	A	G	11: 115,744,631 (GRCm39)	H876R	probably benign	Het
Lrp4	T	C	2: 91,317,396 (GRCm39)	I840T	probably damaging	Het
Myo9a	T	A	9: 59,762,658 (GRCm39)	F796L	probably benign	Het
Naip1	A	G	13: 100,545,629 (GRCm39)	S1300P	probably benign	Het
Nfat5	T	A	8: 108,093,847 (GRCm39)	I602N	probably damaging	Het
Omt2a	T	C	9: 78,220,238 (GRCm39)	M64V	probably benign	Het
Pcnx1	T	C	12: 82,038,809 (GRCm39)	S2025P	probably damaging	Het
Pemt	A	G	11: 59,874,293 (GRCm39)	L62P	probably damaging	Het
Polrmt	A	G	10: 79,576,971 (GRCm39)	V399A	probably benign	Het
Rasgrp4	T	C	7: 28,850,898 (GRCm39)	S77P	possibly damaging	Het
Rrm2b	G	A	15: 37,944,804 (GRCm39)	P111L	probably damaging	Het
Slc10a4-ps	A	T	5: 72,743,547 (GRCm39)		probably null	Het
Thap12	A	G	7: 98,362,110 (GRCm39)	*121W	probably null	Het
Tnik	A	G	3: 28,658,316 (GRCm39)		probably benign	Het
Trio	G	A	15: 27,818,253 (GRCm39)		probably benign	Het
Zfhx4	A	G	3: 5,310,407 (GRCm39)	E930G	probably damaging	Het
Zfp335	G	T	2: 164,749,422 (GRCm39)	T299K	probably benign	Het

Other mutations in Gm5916

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02103:Gm5916	APN	9	36,039,970 (GRCm39)	missense	probably damaging	0.97
IGL02665:Gm5916	APN	9	36,039,962 (GRCm39)	missense	possibly damaging	0.66
R5071:Gm5916	UTSW	9	36,039,964 (GRCm39)	missense	probably benign	0.00
R5347:Gm5916	UTSW	9	36,032,012 (GRCm39)	missense	probably benign	0.03
R6996:Gm5916	UTSW	9	36,039,935 (GRCm39)	missense	probably benign	0.14
R7213:Gm5916	UTSW	9	36,039,946 (GRCm39)	missense	possibly damaging	0.95
R7256:Gm5916	UTSW	9	36,032,285 (GRCm39)	missense	possibly damaging	0.78
R7890:Gm5916	UTSW	9	36,032,291 (GRCm39)	missense	possibly damaging	0.92
R8987:Gm5916	UTSW	9	36,032,286 (GRCm39)	missense	probably benign	0.16
R9112:Gm5916	UTSW	9	36,032,258 (GRCm39)	missense	probably damaging	0.98
R9140:Gm5916	UTSW	9	36,031,982 (GRCm39)	missense	unknown
R9187:Gm5916	UTSW	9	36,032,020 (GRCm39)	missense	probably benign	0.03

Posted On

2013-06-21