Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01067:Ncor1'

52210

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ncor1

Ensembl Gene

ENSMUSG00000018501

Gene Name

nuclear receptor co-repressor 1

Synonyms

Rxrip13, 5730405M06Rik, A230020K14Rik, N-CoR

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL01067

Quality Score

Status

Chromosome

Chromosomal Location

62207132-62348200 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 62283354 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Glutamine at position 444 (H444Q)

Ref Sequence

ENSEMBL: ENSMUSP00000098628 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000018645] [ENSMUST00000101066] [ENSMUST00000101067] [ENSMUST00000127471] [ENSMUST00000151498] [ENSMUST00000155486]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000018645
AA Change: H444Q

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000018645
Gene: ENSMUSG00000018501
AA Change: H444Q

Domain	Start	End	E-Value	Type
low complexity region	51	74	N/A	INTRINSIC
Pfam:GPS2_interact	150	239	1.4e-37	PFAM
coiled coil region	302	329	N/A	INTRINSIC
low complexity region	349	366	N/A	INTRINSIC
SANT	437	485	2.76e-7	SMART
coiled coil region	507	544	N/A	INTRINSIC
low complexity region	593	617	N/A	INTRINSIC
SANT	624	672	3.29e-14	SMART
low complexity region	710	731	N/A	INTRINSIC
low complexity region	771	788	N/A	INTRINSIC
low complexity region	888	899	N/A	INTRINSIC
low complexity region	987	995	N/A	INTRINSIC
low complexity region	1002	1013	N/A	INTRINSIC
low complexity region	1036	1049	N/A	INTRINSIC
internal_repeat_2	1061	1298	1.62e-6	PROSPERO
internal_repeat_2	1299	1515	1.62e-6	PROSPERO
low complexity region	1516	1527	N/A	INTRINSIC
coiled coil region	1712	1749	N/A	INTRINSIC
low complexity region	1834	1848	N/A	INTRINSIC
low complexity region	1969	1980	N/A	INTRINSIC
low complexity region	2036	2055	N/A	INTRINSIC
PDB:3N00\|B	2064	2084	4e-7	PDB
low complexity region	2086	2101	N/A	INTRINSIC
low complexity region	2157	2168	N/A	INTRINSIC
PDB:2OVM\|B	2267	2290	2e-8	PDB
low complexity region	2311	2324	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000101066
AA Change: H444Q

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000098627
Gene: ENSMUSG00000018501
AA Change: H444Q

Domain	Start	End	E-Value	Type
low complexity region	51	74	N/A	INTRINSIC
coiled coil region	176	217	N/A	INTRINSIC
coiled coil region	302	329	N/A	INTRINSIC
low complexity region	349	366	N/A	INTRINSIC
SANT	437	485	2.76e-7	SMART
coiled coil region	507	544	N/A	INTRINSIC
low complexity region	593	617	N/A	INTRINSIC
SANT	624	672	3.29e-14	SMART
low complexity region	710	731	N/A	INTRINSIC
low complexity region	771	788	N/A	INTRINSIC
low complexity region	888	899	N/A	INTRINSIC
low complexity region	987	995	N/A	INTRINSIC
low complexity region	1002	1013	N/A	INTRINSIC
low complexity region	1036	1049	N/A	INTRINSIC
internal_repeat_2	1061	1298	1.62e-6	PROSPERO
internal_repeat_2	1299	1515	1.62e-6	PROSPERO
low complexity region	1516	1527	N/A	INTRINSIC
coiled coil region	1712	1749	N/A	INTRINSIC
low complexity region	1834	1848	N/A	INTRINSIC
low complexity region	1969	1980	N/A	INTRINSIC
low complexity region	2036	2055	N/A	INTRINSIC
PDB:3N00\|B	2064	2084	4e-7	PDB
low complexity region	2086	2101	N/A	INTRINSIC
low complexity region	2157	2168	N/A	INTRINSIC
PDB:2OVM\|B	2267	2290	2e-8	PDB
low complexity region	2311	2324	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000101067
AA Change: H444Q

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000098628
Gene: ENSMUSG00000018501
AA Change: H444Q

Domain	Start	End	E-Value	Type
low complexity region	51	74	N/A	INTRINSIC
coiled coil region	176	217	N/A	INTRINSIC
coiled coil region	302	329	N/A	INTRINSIC
low complexity region	349	366	N/A	INTRINSIC
SANT	437	485	2.76e-7	SMART
coiled coil region	507	544	N/A	INTRINSIC
low complexity region	593	617	N/A	INTRINSIC
SANT	624	672	3.29e-14	SMART
low complexity region	716	734	N/A	INTRINSIC
low complexity region	838	849	N/A	INTRINSIC
low complexity region	937	945	N/A	INTRINSIC
low complexity region	952	963	N/A	INTRINSIC
low complexity region	986	999	N/A	INTRINSIC
low complexity region	1448	1459	N/A	INTRINSIC
coiled coil region	1645	1682	N/A	INTRINSIC
low complexity region	1767	1781	N/A	INTRINSIC
low complexity region	1902	1913	N/A	INTRINSIC
low complexity region	1969	1988	N/A	INTRINSIC
PDB:3N00\|B	1997	2017	4e-7	PDB
low complexity region	2019	2034	N/A	INTRINSIC
low complexity region	2089	2100	N/A	INTRINSIC
PDB:2OVM\|B	2199	2222	2e-8	PDB
low complexity region	2243	2256	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000101068

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000124027

Predicted Effect

probably benign
Transcript: ENSMUST00000127471
AA Change: H444Q

PolyPhen 2 Score 0.007 (Sensitivity: 0.96; Specificity: 0.75)

SMART Domains

Protein: ENSMUSP00000121806
Gene: ENSMUSG00000018501
AA Change: H444Q

Domain	Start	End	E-Value	Type
low complexity region	51	74	N/A	INTRINSIC
coiled coil region	176	217	N/A	INTRINSIC
coiled coil region	302	329	N/A	INTRINSIC
low complexity region	349	366	N/A	INTRINSIC
SANT	437	485	2.76e-7	SMART
coiled coil region	508	545	N/A	INTRINSIC
low complexity region	594	618	N/A	INTRINSIC
SANT	625	673	3.29e-14	SMART
low complexity region	711	732	N/A	INTRINSIC
low complexity region	756	773	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000151498
AA Change: H44Q

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000125317
Gene: ENSMUSG00000018501
AA Change: H44Q

Domain	Start	End	E-Value	Type
SANT	37	85	2.76e-7	SMART
coiled coil region	107	144	N/A	INTRINSIC
low complexity region	193	217	N/A	INTRINSIC
SANT	224	272	3.29e-14	SMART
low complexity region	316	337	N/A	INTRINSIC
low complexity region	361	378	N/A	INTRINSIC
low complexity region	478	489	N/A	INTRINSIC
low complexity region	577	585	N/A	INTRINSIC
low complexity region	592	603	N/A	INTRINSIC
low complexity region	684	697	N/A	INTRINSIC
internal_repeat_2	700	830	5.77e-7	PROSPERO
internal_repeat_2	855	961	5.77e-7	PROSPERO

Predicted Effect

probably benign
Transcript: ENSMUST00000155486
AA Change: H453Q

PolyPhen 2 Score 0.027 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000122647
Gene: ENSMUSG00000018501
AA Change: H453Q

Domain	Start	End	E-Value	Type
low complexity region	51	74	N/A	INTRINSIC
coiled coil region	176	217	N/A	INTRINSIC
coiled coil region	311	338	N/A	INTRINSIC
low complexity region	358	375	N/A	INTRINSIC
SANT	446	494	2.76e-7	SMART
coiled coil region	516	541	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000160171

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
PHENOTYPE: Mice homozygous for a targeted mutation in this gene exhibit embryonic lethality with erythrocytic, thymocytic and central nervous system development abnormalities. Mice homozygous for a hypomorphic allele exhibit increased thyroid hormone sensitivity under hypothyroid conditions. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110038F14Rik	G	A	15: 76,834,475 (GRCm39)	V124I	probably damaging	Het
A330008L17Rik	T	C	8: 100,148,586 (GRCm39)		noncoding transcript	Het
Acp4	C	T	7: 43,902,876 (GRCm39)	V331I	probably benign	Het
Aen	G	A	7: 78,557,050 (GRCm39)	M299I	probably damaging	Het
Alg6	T	C	4: 99,629,807 (GRCm39)	V128A	probably benign	Het
Ank3	A	G	10: 69,686,026 (GRCm39)	K280E	probably damaging	Het
Bfar	T	C	16: 13,503,105 (GRCm39)	C36R	probably damaging	Het
Car14	A	G	3: 95,806,128 (GRCm39)	I311T	probably damaging	Het
Cd300c	T	C	11: 114,851,253 (GRCm39)		probably benign	Het
Cfap100	T	A	6: 90,383,096 (GRCm39)	E513V	probably damaging	Het
Clip1	C	A	5: 123,768,867 (GRCm39)	K612N	probably damaging	Het
Depdc5	A	G	5: 33,056,411 (GRCm39)		probably null	Het
Dock3	A	T	9: 106,959,572 (GRCm39)		probably null	Het
Dph6	A	T	2: 114,478,290 (GRCm39)	M17K	probably damaging	Het
Enkur	T	C	2: 21,194,042 (GRCm39)	Q177R	probably benign	Het
Faap100	T	C	11: 120,262,958 (GRCm39)	H800R	probably damaging	Het
Fastkd2	T	G	1: 63,776,930 (GRCm39)		probably benign	Het
Fcgr2b	A	T	1: 170,795,622 (GRCm39)	N102K	possibly damaging	Het
Fezf1	C	T	6: 23,247,842 (GRCm39)	V78I	possibly damaging	Het
Fmn2	A	T	1: 174,330,885 (GRCm39)	D425V	unknown	Het
Fnta	G	A	8: 26,497,229 (GRCm39)	Q207*	probably null	Het
Fpr3	T	A	17: 18,190,828 (GRCm39)	V33D	probably benign	Het
Fshr	C	T	17: 89,292,821 (GRCm39)	C619Y	possibly damaging	Het
Gbp3	T	C	3: 142,272,358 (GRCm39)		probably null	Het
Gjb2	A	G	14: 57,337,629 (GRCm39)	V193A	possibly damaging	Het
Il4ra	A	G	7: 125,174,333 (GRCm39)	T292A	probably benign	Het
Lama5	A	G	2: 179,818,336 (GRCm39)		probably benign	Het
Marveld3	G	T	8: 110,688,596 (GRCm39)	D48E	possibly damaging	Het
Meox1	A	T	11: 101,784,599 (GRCm39)	I78N	probably benign	Het
Ndst3	T	C	3: 123,340,466 (GRCm39)	Q784R	probably damaging	Het
Or10ag2	A	G	2: 87,248,714 (GRCm39)	I107M	probably benign	Het
Or4k44	T	A	2: 111,368,359 (GRCm39)	I92F	probably damaging	Het
Pld5	A	T	1: 176,102,445 (GRCm39)		probably benign	Het
Plk1	G	A	7: 121,768,148 (GRCm39)	R456H	probably damaging	Het
Polr2a	T	A	11: 69,638,840 (GRCm39)	I65F	possibly damaging	Het
Ptprd	T	A	4: 75,977,922 (GRCm39)	I196F	probably damaging	Het
Qsox2	T	C	2: 26,118,408 (GRCm39)	N121S	probably damaging	Het
Reln	A	G	5: 22,184,664 (GRCm39)	L1617S	probably damaging	Het
Rragc	T	C	4: 123,823,761 (GRCm39)	F345L	probably benign	Het
Sass6	A	T	3: 116,407,605 (GRCm39)	E240D	possibly damaging	Het
Shcbp1l	A	C	1: 153,311,770 (GRCm39)	S308R	possibly damaging	Het
Slc1a5	T	A	7: 16,520,804 (GRCm39)	C224*	probably null	Het
Slc27a5	T	C	7: 12,722,999 (GRCm39)	E567G	probably damaging	Het
Synj2	T	A	17: 6,088,201 (GRCm39)	N1417K	possibly damaging	Het
Tbc1d9	A	G	8: 83,960,791 (GRCm39)	T214A	probably damaging	Het
Tjp3	C	A	10: 81,109,699 (GRCm39)	V835L	probably benign	Het
Trpc4	C	A	3: 54,129,983 (GRCm39)	Q250K	probably benign	Het
Ttn	A	T	2: 76,575,506 (GRCm39)	I25129N	probably damaging	Het
Ube4a	T	A	9: 44,856,163 (GRCm39)	Y523F	probably damaging	Het
Zfp971	G	A	2: 177,665,175 (GRCm39)		probably null	Het

Other mutations in Ncor1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01343:Ncor1	APN	11	62,216,312 (GRCm39)	critical splice donor site	probably null
IGL01392:Ncor1	APN	11	62,231,420 (GRCm39)	missense	probably damaging	0.99
IGL01402:Ncor1	APN	11	62,231,300 (GRCm39)	missense	probably damaging	1.00
IGL01714:Ncor1	APN	11	62,225,410 (GRCm39)	missense	possibly damaging	0.58
IGL01772:Ncor1	APN	11	62,240,173 (GRCm39)	intron	probably benign
IGL01889:Ncor1	APN	11	62,225,427 (GRCm39)	missense	possibly damaging	0.69
IGL02058:Ncor1	APN	11	62,235,463 (GRCm39)	missense	probably damaging	1.00
IGL02065:Ncor1	APN	11	62,310,435 (GRCm39)	missense	possibly damaging	0.95
IGL02073:Ncor1	APN	11	62,249,743 (GRCm39)	missense	probably damaging	0.99
IGL02176:Ncor1	APN	11	62,220,485 (GRCm39)	unclassified	probably benign
IGL02288:Ncor1	APN	11	62,240,229 (GRCm39)	missense	probably benign	0.01
IGL02348:Ncor1	APN	11	62,224,485 (GRCm39)	splice site	probably benign
IGL02608:Ncor1	APN	11	62,264,040 (GRCm39)	missense	probably benign	0.07
laggard	UTSW	11	62,260,130 (GRCm39)	missense	probably damaging	1.00
Shortstep	UTSW	11	62,225,367 (GRCm39)	missense	probably damaging	1.00
LCD18:Ncor1	UTSW	11	62,419,782 (GRCm38)	critical splice acceptor site	probably benign
PIT4382001:Ncor1	UTSW	11	62,235,489 (GRCm39)	missense	probably damaging	0.96
PIT4576001:Ncor1	UTSW	11	62,224,543 (GRCm39)	missense	probably damaging	0.99
R0026:Ncor1	UTSW	11	62,329,255 (GRCm39)	missense	probably damaging	1.00
R0038:Ncor1	UTSW	11	62,283,377 (GRCm39)	missense	probably damaging	0.99
R0038:Ncor1	UTSW	11	62,283,377 (GRCm39)	missense	probably damaging	0.99
R0103:Ncor1	UTSW	11	62,233,871 (GRCm39)	missense	possibly damaging	0.85
R0103:Ncor1	UTSW	11	62,233,871 (GRCm39)	missense	possibly damaging	0.85
R0144:Ncor1	UTSW	11	62,283,421 (GRCm39)	missense	probably damaging	1.00
R0427:Ncor1	UTSW	11	62,301,746 (GRCm39)	missense	probably damaging	1.00
R0501:Ncor1	UTSW	11	62,264,148 (GRCm39)	missense	possibly damaging	0.73
R0544:Ncor1	UTSW	11	62,224,603 (GRCm39)	missense	probably damaging	1.00
R0544:Ncor1	UTSW	11	62,224,602 (GRCm39)	missense	probably damaging	1.00
R0563:Ncor1	UTSW	11	62,234,056 (GRCm39)	missense	probably damaging	0.97
R1074:Ncor1	UTSW	11	62,283,377 (GRCm39)	missense	probably damaging	0.99
R1266:Ncor1	UTSW	11	62,224,866 (GRCm39)	missense	probably damaging	0.98
R1444:Ncor1	UTSW	11	62,294,632 (GRCm39)	missense	probably damaging	1.00
R1452:Ncor1	UTSW	11	62,225,457 (GRCm39)	missense	probably damaging	1.00
R1534:Ncor1	UTSW	11	62,269,330 (GRCm39)	missense	possibly damaging	0.92
R1710:Ncor1	UTSW	11	62,313,831 (GRCm39)	missense	probably damaging	1.00
R1762:Ncor1	UTSW	11	62,275,610 (GRCm39)	missense	possibly damaging	0.82
R1771:Ncor1	UTSW	11	62,217,938 (GRCm39)	missense	probably damaging	1.00
R1864:Ncor1	UTSW	11	62,272,245 (GRCm39)	missense	probably damaging	1.00
R1902:Ncor1	UTSW	11	62,228,984 (GRCm39)	missense	probably damaging	1.00
R1906:Ncor1	UTSW	11	62,240,211 (GRCm39)	missense	possibly damaging	0.81
R2009:Ncor1	UTSW	11	62,216,427 (GRCm39)	missense	probably benign	0.43
R3708:Ncor1	UTSW	11	62,235,513 (GRCm39)	missense	probably damaging	1.00
R3825:Ncor1	UTSW	11	62,264,183 (GRCm39)	missense	probably benign	0.00
R3923:Ncor1	UTSW	11	62,216,442 (GRCm39)	missense	probably damaging	1.00
R3966:Ncor1	UTSW	11	62,235,583 (GRCm39)	missense	probably damaging	1.00
R4049:Ncor1	UTSW	11	62,220,494 (GRCm39)	splice site	probably null
R4350:Ncor1	UTSW	11	62,301,644 (GRCm39)	critical splice donor site	probably null
R4351:Ncor1	UTSW	11	62,301,644 (GRCm39)	critical splice donor site	probably null
R4359:Ncor1	UTSW	11	62,249,736 (GRCm39)	missense	probably damaging	1.00
R4712:Ncor1	UTSW	11	62,235,660 (GRCm39)	missense	probably damaging	1.00
R4723:Ncor1	UTSW	11	62,269,438 (GRCm39)	missense	probably benign	0.26
R4863:Ncor1	UTSW	11	62,283,464 (GRCm39)	missense	possibly damaging	0.92
R4875:Ncor1	UTSW	11	62,324,437 (GRCm39)	small deletion	probably benign
R4956:Ncor1	UTSW	11	62,231,431 (GRCm39)	missense	probably damaging	1.00
R4993:Ncor1	UTSW	11	62,234,167 (GRCm39)	missense	probably damaging	1.00
R5079:Ncor1	UTSW	11	62,236,063 (GRCm39)	missense	possibly damaging	0.92
R5144:Ncor1	UTSW	11	62,240,290 (GRCm39)	missense	probably damaging	1.00
R5223:Ncor1	UTSW	11	62,229,826 (GRCm39)	missense	probably damaging	1.00
R5243:Ncor1	UTSW	11	62,229,788 (GRCm39)	missense	probably damaging	1.00
R5271:Ncor1	UTSW	11	62,231,371 (GRCm39)	missense	probably damaging	1.00
R5285:Ncor1	UTSW	11	62,283,475 (GRCm39)	missense	probably damaging	1.00
R5533:Ncor1	UTSW	11	62,233,837 (GRCm39)	missense	probably benign	0.00
R5580:Ncor1	UTSW	11	62,280,604 (GRCm39)	nonsense	probably null
R5593:Ncor1	UTSW	11	62,260,130 (GRCm39)	missense	probably damaging	1.00
R5609:Ncor1	UTSW	11	62,249,679 (GRCm39)	splice site	probably null
R5632:Ncor1	UTSW	11	62,229,060 (GRCm39)	missense	possibly damaging	0.85
R5830:Ncor1	UTSW	11	62,235,589 (GRCm39)	missense	possibly damaging	0.71
R5896:Ncor1	UTSW	11	62,274,016 (GRCm39)	missense	probably damaging	1.00
R5973:Ncor1	UTSW	11	62,240,136 (GRCm39)	splice site	probably null
R6013:Ncor1	UTSW	11	62,211,903 (GRCm39)	missense	probably benign
R6019:Ncor1	UTSW	11	62,263,987 (GRCm39)	missense	probably benign	0.00
R6032:Ncor1	UTSW	11	62,264,147 (GRCm39)	missense	possibly damaging	0.54
R6032:Ncor1	UTSW	11	62,264,147 (GRCm39)	missense	possibly damaging	0.54
R6075:Ncor1	UTSW	11	62,208,675 (GRCm39)	missense	probably damaging	1.00
R6091:Ncor1	UTSW	11	62,310,443 (GRCm39)	missense	probably damaging	0.98
R6248:Ncor1	UTSW	11	62,257,808 (GRCm39)	missense	probably damaging	1.00
R6281:Ncor1	UTSW	11	62,264,371 (GRCm39)	missense	possibly damaging	0.71
R6351:Ncor1	UTSW	11	62,264,124 (GRCm39)	missense	probably benign	0.30
R6469:Ncor1	UTSW	11	62,234,128 (GRCm39)	missense	probably damaging	1.00
R6502:Ncor1	UTSW	11	62,272,240 (GRCm39)	nonsense	probably null
R6614:Ncor1	UTSW	11	62,221,645 (GRCm39)	missense	probably benign	0.01
R6650:Ncor1	UTSW	11	62,225,367 (GRCm39)	missense	probably damaging	1.00
R6765:Ncor1	UTSW	11	62,264,272 (GRCm39)	missense	probably benign	0.01
R6852:Ncor1	UTSW	11	62,234,071 (GRCm39)	missense	probably damaging	0.97
R6909:Ncor1	UTSW	11	62,220,312 (GRCm39)	missense	probably damaging	1.00
R6965:Ncor1	UTSW	11	62,244,059 (GRCm39)	critical splice donor site	probably null
R7054:Ncor1	UTSW	11	62,275,619 (GRCm39)	missense	probably null
R7248:Ncor1	UTSW	11	62,275,598 (GRCm39)	missense	possibly damaging	0.89
R7352:Ncor1	UTSW	11	62,224,737 (GRCm39)	missense	probably damaging	0.99
R7396:Ncor1	UTSW	11	62,234,044 (GRCm39)	missense	probably damaging	0.99
R7434:Ncor1	UTSW	11	62,274,025 (GRCm39)	missense	probably damaging	0.99
R7552:Ncor1	UTSW	11	62,264,250 (GRCm39)	missense	possibly damaging	0.53
R7565:Ncor1	UTSW	11	62,292,091 (GRCm39)	missense	probably damaging	1.00
R7575:Ncor1	UTSW	11	62,274,082 (GRCm39)	missense	probably benign	0.21
R7622:Ncor1	UTSW	11	62,208,794 (GRCm39)	missense	probably benign	0.00
R7664:Ncor1	UTSW	11	62,289,154 (GRCm39)	missense	probably damaging	1.00
R7814:Ncor1	UTSW	11	62,224,752 (GRCm39)	missense	probably damaging	0.99
R7963:Ncor1	UTSW	11	62,225,359 (GRCm39)	missense	probably benign	0.28
R7990:Ncor1	UTSW	11	62,240,321 (GRCm39)	critical splice acceptor site	probably null
R8302:Ncor1	UTSW	11	62,224,681 (GRCm39)	missense	probably benign	0.00
R8334:Ncor1	UTSW	11	62,274,070 (GRCm39)	missense	probably damaging	0.99
R8512:Ncor1	UTSW	11	62,324,437 (GRCm39)	small deletion	probably benign
R8728:Ncor1	UTSW	11	62,221,685 (GRCm39)	missense	probably benign	0.04
R8777:Ncor1	UTSW	11	62,324,494 (GRCm39)	missense	probably damaging	1.00
R8777:Ncor1	UTSW	11	62,324,492 (GRCm39)	missense	probably benign	0.03
R8777-TAIL:Ncor1	UTSW	11	62,324,494 (GRCm39)	missense	probably damaging	1.00
R8777-TAIL:Ncor1	UTSW	11	62,324,492 (GRCm39)	missense	probably benign	0.03
R8821:Ncor1	UTSW	11	62,260,234 (GRCm39)	missense	probably benign	0.07
R8831:Ncor1	UTSW	11	62,260,234 (GRCm39)	missense	probably benign	0.07
R8988:Ncor1	UTSW	11	62,233,871 (GRCm39)	nonsense	probably null
R9111:Ncor1	UTSW	11	62,280,585 (GRCm39)	missense	possibly damaging	0.95
R9147:Ncor1	UTSW	11	62,224,672 (GRCm39)	missense	probably damaging	1.00
R9391:Ncor1	UTSW	11	62,216,376 (GRCm39)	nonsense	probably null
R9467:Ncor1	UTSW	11	62,324,448 (GRCm39)	small insertion	probably benign
R9467:Ncor1	UTSW	11	62,324,437 (GRCm39)	small insertion	probably benign
R9510:Ncor1	UTSW	11	62,324,442 (GRCm39)	small insertion	probably benign
R9511:Ncor1	UTSW	11	62,324,449 (GRCm39)	small insertion	probably benign
R9560:Ncor1	UTSW	11	62,263,948 (GRCm39)	missense	possibly damaging	0.96
R9687:Ncor1	UTSW	11	62,260,193 (GRCm39)	missense	possibly damaging	0.93
X0065:Ncor1	UTSW	11	62,249,817 (GRCm39)	missense	probably benign	0.23
X0065:Ncor1	UTSW	11	62,245,395 (GRCm39)	critical splice donor site	probably null
Z1176:Ncor1	UTSW	11	62,329,342 (GRCm39)	critical splice acceptor site	probably null

Posted On

2013-06-21