Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01147:Zfp367'

52618

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp367

Ensembl Gene

ENSMUSG00000044934

Gene Name

zinc finger protein 367

Synonyms

8030486J21Rik, ZFF29a, ZFF29b

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01147

Quality Score

Status

Chromosome

Chromosomal Location

64280836-64301013 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 64283253 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 300 (S300P)

Ref Sequence

ENSEMBL: ENSMUSP00000050854 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000059817]

AlphaFold

Q0VDT2

Predicted Effect

probably damaging
Transcript: ENSMUST00000059817
AA Change: S300P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000050854
Gene: ENSMUSG00000044934
AA Change: S300P

Domain	Start	End	E-Value	Type
low complexity region	5	14	N/A	INTRINSIC
low complexity region	37	59	N/A	INTRINSIC
low complexity region	77	94	N/A	INTRINSIC
low complexity region	105	113	N/A	INTRINSIC
ZnF_C2H2	157	179	3.44e-4	SMART
ZnF_C2H2	185	209	2.4e-3	SMART
coiled coil region	299	332	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000134136

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000152644

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 36 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc3	A	G	11: 94,234,611 (GRCm39)		probably benign	Het
Aen	G	A	7: 78,557,050 (GRCm39)	M299I	probably damaging	Het
Cdh1	C	A	8: 107,387,516 (GRCm39)	T472K	probably damaging	Het
Cfap206	C	T	4: 34,721,562 (GRCm39)	S162N	probably damaging	Het
Cfap57	A	T	4: 118,446,198 (GRCm39)	V688E	probably damaging	Het
Cfp	G	A	X: 20,794,981 (GRCm39)	R155C	probably damaging	Het
Chst7	T	C	X: 19,926,991 (GRCm39)	I346T	probably damaging	Het
Crybg2	G	A	4: 133,816,575 (GRCm39)		probably null	Het
Ctsc	T	A	7: 87,951,479 (GRCm39)	V242D	possibly damaging	Het
Cyp27b1	C	T	10: 126,886,255 (GRCm39)	T312I	possibly damaging	Het
D6Wsu163e	A	G	6: 126,921,815 (GRCm39)	D80G	possibly damaging	Het
Enpp3	G	T	10: 24,650,805 (GRCm39)	T777K	probably damaging	Het
H2-M1	T	A	17: 36,982,199 (GRCm39)	H134L	possibly damaging	Het
Heatr1	T	C	13: 12,452,793 (GRCm39)	S2105P	probably damaging	Het
Herc2	T	C	7: 55,806,697 (GRCm39)	S2388P	probably benign	Het
Igkv6-23	A	G	6: 70,237,922 (GRCm39)		probably benign	Het
Il1rapl2	C	T	X: 137,121,325 (GRCm39)		probably benign	Het
Itpka	T	C	2: 119,573,254 (GRCm39)	L132P	probably benign	Het
Jak3	T	C	8: 72,136,047 (GRCm39)	S616P	probably benign	Het
Kcnj11	T	C	7: 45,748,193 (GRCm39)	K377E	probably benign	Het
Map4k3	A	T	17: 80,944,147 (GRCm39)		probably null	Het
Parp1	T	C	1: 180,417,145 (GRCm39)	I643T	probably damaging	Het
Phf3	T	C	1: 30,843,250 (GRCm39)	D1903G	probably damaging	Het
Picalm	G	T	7: 89,826,800 (GRCm39)	S416I	probably benign	Het
Pkn2	T	C	3: 142,534,770 (GRCm39)	N285S	probably benign	Het
Sh3gl2	A	C	4: 85,265,433 (GRCm39)		probably benign	Het
Smpd1	C	A	7: 105,204,943 (GRCm39)	T274K	probably damaging	Het
Snap91	G	A	9: 86,680,611 (GRCm39)	T424M	probably benign	Het
Sox13	T	A	1: 133,320,873 (GRCm39)	T46S	probably benign	Het
Syne1	G	A	10: 5,002,691 (GRCm39)	Q8075*	probably null	Het
Trio	T	C	15: 27,881,406 (GRCm39)	E555G	probably damaging	Het
Upf3b	T	C	X: 36,360,586 (GRCm39)	E298G	probably damaging	Het
Vmn1r158	A	G	7: 22,490,204 (GRCm39)	S2P	probably benign	Het
Vmn1r6	T	A	6: 56,979,626 (GRCm39)	L74H	probably damaging	Het
Vwa2	T	C	19: 56,890,066 (GRCm39)	S224P	probably damaging	Het
Wbp1l	T	A	19: 46,632,808 (GRCm39)	V36E	probably damaging	Het

Other mutations in Zfp367

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL03151:Zfp367	APN	13	64,293,445 (GRCm39)	missense	probably damaging	1.00
IGL03267:Zfp367	APN	13	64,292,097 (GRCm39)	splice site	probably benign
fisher	UTSW	13	64,293,457 (GRCm39)	missense	probably damaging	1.00
Otter	UTSW	13	64,292,069 (GRCm39)	nonsense	probably null
R4608:Zfp367	UTSW	13	64,283,238 (GRCm39)	missense	probably damaging	1.00
R6180:Zfp367	UTSW	13	64,283,204 (GRCm39)	missense	probably damaging	1.00
R6531:Zfp367	UTSW	13	64,292,064 (GRCm39)	missense	probably damaging	1.00
R7727:Zfp367	UTSW	13	64,293,457 (GRCm39)	missense	probably damaging	1.00
R8247:Zfp367	UTSW	13	64,300,482 (GRCm39)	missense	probably benign
R8754:Zfp367	UTSW	13	64,292,069 (GRCm39)	nonsense	probably null
R9557:Zfp367	UTSW	13	64,300,586 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-06-21