Mutagenetix > Incidental Mutation

Incidental Mutation 'R6572:Ahnak'

526306

Institutional Source

Beutler Lab

Gene Symbol

Ahnak

Ensembl Gene

ENSMUSG00000069833

Gene Name

AHNAK nucleoprotein

Synonyms

DY6, 1110004P15Rik, 2310047C17Rik

MMRRC Submission

044696-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.313) question?

Stock #

R6572 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

8966648-9054278 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 8985340 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Arginine at position 2208 (K2208R)

Ref Sequence

ENSEMBL: ENSMUSP00000090633 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092955] [ENSMUST00000092956]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000092955

SMART Domains

Protein: ENSMUSP00000090632
Gene: ENSMUSG00000069833

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000092956
AA Change: K2208R

PolyPhen 2 Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000090633
Gene: ENSMUSG00000069833
AA Change: K2208R

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART
internal_repeat_2	163	1515	5.22e-182	PROSPERO
internal_repeat_1	224	2314	N/A	PROSPERO
internal_repeat_2	1532	3028	5.22e-182	PROSPERO
internal_repeat_1	2660	5095	N/A	PROSPERO
low complexity region	5336	5353	N/A	INTRINSIC
low complexity region	5493	5504	N/A	INTRINSIC
low complexity region	5580	5600	N/A	INTRINSIC
low complexity region	5620	5636	N/A	INTRINSIC

Meta Mutation Damage Score

0.1428

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.4%
20x: 98.2%

Validation Efficiency

97% (62/64)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 61 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930447A16Rik	C	T	15: 37,425,961 (GRCm39)	Q34*	probably null	Het
Adamts3	T	A	5: 90,009,468 (GRCm39)	H65L	possibly damaging	Het
Ago2	A	G	15: 72,998,826 (GRCm39)	V257A	probably benign	Het
Apc2	C	T	10: 80,147,613 (GRCm39)	S860L	probably damaging	Het
Arhgap18	A	G	10: 26,722,412 (GRCm39)		probably null	Het
Arhgap33	T	C	7: 30,226,635 (GRCm39)	E524G	probably damaging	Het
Ascc3	C	T	10: 50,566,343 (GRCm39)	Q763*	probably null	Het
Atg2a	T	C	19: 6,304,695 (GRCm39)	L1184P	probably damaging	Het
Baiap2l1	A	G	5: 144,223,112 (GRCm39)	L75P	probably damaging	Het
Btbd17	A	T	11: 114,683,046 (GRCm39)	L222Q	probably damaging	Het
Chst13	G	T	6: 90,286,588 (GRCm39)	R125S	probably benign	Het
Cpsf1	CCCCTGCATGAGGCAGGTCCC	CCCC	15: 76,481,655 (GRCm39)		probably null	Het
Cracr2a	T	C	6: 127,585,715 (GRCm39)		probably null	Het
Dchs1	T	A	7: 105,408,013 (GRCm39)	T1940S	possibly damaging	Het
Ddit4l	G	T	3: 137,332,111 (GRCm39)	R159L	probably benign	Het
Dock3	A	G	9: 106,866,674 (GRCm39)	Y679H	probably damaging	Het
Dyrk4	T	G	6: 126,874,201 (GRCm39)	I130L	probably benign	Het
Eml2	T	C	7: 18,930,539 (GRCm39)	V373A	possibly damaging	Het
Entrep1	A	T	19: 23,962,082 (GRCm39)	M307K	possibly damaging	Het
Ephb1	A	G	9: 101,944,097 (GRCm39)	F312L	probably benign	Het
Fndc9	A	T	11: 46,128,708 (GRCm39)	I76F	probably damaging	Het
Frk	G	A	10: 34,459,963 (GRCm39)	R186K	probably benign	Het
Gpatch3	G	T	4: 133,302,191 (GRCm39)	G41C	probably damaging	Het
Greb1l	T	A	18: 10,522,131 (GRCm39)	H633Q	probably benign	Het
Gstt4	T	A	10: 75,650,954 (GRCm39)	T223S	probably damaging	Het
Hpd	C	T	5: 123,318,739 (GRCm39)	E60K	probably benign	Het
Inpp5d	C	T	1: 87,623,118 (GRCm39)	P403S	probably damaging	Het
Klk1b9	T	A	7: 43,629,159 (GRCm39)	I189K	probably benign	Het
Kmt2e	A	T	5: 23,702,579 (GRCm39)	H239L	possibly damaging	Het
Lrriq3	A	G	3: 154,887,312 (GRCm39)	D344G	probably benign	Het
Neb	A	G	2: 52,168,859 (GRCm39)	I1892T	probably damaging	Het
Neto2	A	T	8: 86,397,033 (GRCm39)	I73N	possibly damaging	Het
Nipal3	A	T	4: 135,174,564 (GRCm39)	S396T	probably benign	Het
Or1e35	A	G	11: 73,797,629 (GRCm39)	S230P	possibly damaging	Het
Or51q1c	T	A	7: 103,648,391 (GRCm39)		probably null	Het
Phf20l1	T	A	15: 66,481,396 (GRCm39)	V264D	probably damaging	Het
Pigs	A	G	11: 78,230,190 (GRCm39)	Y319C	probably damaging	Het
Pkd2l2	T	C	18: 34,571,824 (GRCm39)	Y608H	probably damaging	Het
Ppard	G	T	17: 28,516,093 (GRCm39)	E106*	probably null	Het
Pramel11	C	T	4: 143,621,943 (GRCm39)	V471I	possibly damaging	Het
Pramel16	A	G	4: 143,676,262 (GRCm39)	S281P	probably benign	Het
Psenen	T	C	7: 30,261,773 (GRCm39)	T48A	probably benign	Het
Ralgps2	A	T	1: 156,651,620 (GRCm39)		probably null	Het
Ripk4	T	A	16: 97,547,105 (GRCm39)	R323*	probably null	Het
Rsf1	CG	CGACGGCGGTG	7: 97,229,115 (GRCm39)		probably benign	Het
Scgb2b24	T	A	7: 33,437,902 (GRCm39)	E68D	probably damaging	Het
Setx	A	G	2: 29,063,706 (GRCm39)	D2334G	possibly damaging	Het
Sh3bp4	A	G	1: 89,072,643 (GRCm39)	D497G	possibly damaging	Het
Smarca2	A	T	19: 26,656,573 (GRCm39)	I850F	possibly damaging	Het
Smyd1	A	G	6: 71,202,396 (GRCm39)	Y270H	probably damaging	Het
Spidr	T	A	16: 15,730,380 (GRCm39)		probably null	Het
Srms	T	C	2: 180,854,450 (GRCm39)	D39G	probably benign	Het
Trpc2	T	A	7: 101,739,213 (GRCm39)	I528N	probably damaging	Het
Tshr	A	G	12: 91,505,134 (GRCm39)	I691V	probably benign	Het
Urb1	A	C	16: 90,584,302 (GRCm39)	V560G	probably benign	Het
Usp37	A	G	1: 74,534,941 (GRCm39)	S2P	possibly damaging	Het
Vmn1r60	G	A	7: 5,547,599 (GRCm39)	S167F	probably benign	Het
Vmn2r89	G	A	14: 51,693,450 (GRCm39)	V267I	probably damaging	Het
Washc3	T	A	10: 88,049,568 (GRCm39)	D63E	probably benign	Het
Wdr89	A	G	12: 75,680,159 (GRCm39)	S32P	probably damaging	Het
Zfp157	T	C	5: 138,455,313 (GRCm39)	S504P	possibly damaging	Het

Other mutations in Ahnak

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00467:Ahnak	APN	19	8,984,587 (GRCm39)	missense	probably damaging	0.99
IGL00509:Ahnak	APN	19	8,987,315 (GRCm39)	missense	possibly damaging	0.94
IGL00539:Ahnak	APN	19	8,985,272 (GRCm39)	missense	possibly damaging	0.50
IGL00558:Ahnak	APN	19	8,981,671 (GRCm39)	missense	possibly damaging	0.93
IGL00567:Ahnak	APN	19	8,990,747 (GRCm39)	missense	probably benign	0.24
IGL00706:Ahnak	APN	19	8,991,094 (GRCm39)	nonsense	probably null
IGL00807:Ahnak	APN	19	8,985,886 (GRCm39)	missense	possibly damaging	0.92
IGL00870:Ahnak	APN	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
IGL01101:Ahnak	APN	19	8,990,251 (GRCm39)	intron	probably benign
IGL01118:Ahnak	APN	19	8,989,942 (GRCm39)	missense	probably damaging	1.00
IGL01288:Ahnak	APN	19	8,979,858 (GRCm39)	missense	possibly damaging	0.94
IGL01324:Ahnak	APN	19	8,980,396 (GRCm39)	missense	probably damaging	1.00
IGL01341:Ahnak	APN	19	8,989,067 (GRCm39)	missense	probably benign
IGL01541:Ahnak	APN	19	8,985,243 (GRCm39)	missense	possibly damaging	0.95
IGL01580:Ahnak	APN	19	8,980,203 (GRCm39)	missense	probably benign	0.02
IGL01595:Ahnak	APN	19	8,980,865 (GRCm39)	nonsense	probably null
IGL01746:Ahnak	APN	19	8,982,276 (GRCm39)	missense	possibly damaging	0.89
IGL01766:Ahnak	APN	19	8,977,482 (GRCm39)	missense	unknown
IGL01821:Ahnak	APN	19	8,989,482 (GRCm39)	missense	probably benign
IGL01913:Ahnak	APN	19	8,983,428 (GRCm39)	nonsense	probably null
IGL01934:Ahnak	APN	19	8,980,021 (GRCm39)	missense	probably damaging	1.00
IGL01940:Ahnak	APN	19	8,983,921 (GRCm39)	missense	probably benign	0.14
IGL01958:Ahnak	APN	19	8,992,273 (GRCm39)	missense	possibly damaging	0.59
IGL02145:Ahnak	APN	19	8,980,219 (GRCm39)	missense	probably benign	0.11
IGL02246:Ahnak	APN	19	8,985,632 (GRCm39)	missense	probably damaging	1.00
IGL02282:Ahnak	APN	19	8,983,351 (GRCm39)	missense	probably damaging	1.00
IGL02428:Ahnak	APN	19	8,992,197 (GRCm39)	missense	possibly damaging	0.83
IGL02442:Ahnak	APN	19	8,981,380 (GRCm39)	missense	probably damaging	1.00
IGL02474:Ahnak	APN	19	8,982,297 (GRCm39)	missense	probably benign	0.13
IGL02483:Ahnak	APN	19	8,980,672 (GRCm39)	missense	probably benign	0.01
IGL02616:Ahnak	APN	19	8,982,991 (GRCm39)	missense	probably benign	0.03
IGL02630:Ahnak	APN	19	8,989,441 (GRCm39)	missense	probably damaging	1.00
IGL02690:Ahnak	APN	19	8,989,948 (GRCm39)	nonsense	probably null
IGL02717:Ahnak	APN	19	8,979,751 (GRCm39)	missense	probably benign	0.00
IGL02721:Ahnak	APN	19	8,987,071 (GRCm39)	missense	probably benign	0.07
IGL02737:Ahnak	APN	19	8,981,957 (GRCm39)	missense	probably benign	0.17
IGL02850:Ahnak	APN	19	8,979,960 (GRCm39)	missense	probably benign	0.00
IGL03071:Ahnak	APN	19	8,989,282 (GRCm39)	missense	possibly damaging	0.63
IGL03072:Ahnak	APN	19	8,983,872 (GRCm39)	missense	probably benign	0.11
IGL03094:Ahnak	APN	19	8,980,911 (GRCm39)	missense	possibly damaging	0.64
IGL03140:Ahnak	APN	19	8,982,576 (GRCm39)	intron	probably benign
IGL03176:Ahnak	APN	19	8,979,813 (GRCm39)	missense	probably damaging	1.00
IGL03176:Ahnak	APN	19	8,985,530 (GRCm39)	missense	possibly damaging	0.56
IGL03189:Ahnak	APN	19	8,988,603 (GRCm39)	missense	possibly damaging	0.65
IGL03357:Ahnak	APN	19	8,986,689 (GRCm39)	intron	probably benign
IGL03371:Ahnak	APN	19	8,981,592 (GRCm39)	missense	possibly damaging	0.91
Eskimo	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
Nanook	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
Netsilik	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
IGL03097:Ahnak	UTSW	19	8,979,751 (GRCm39)	missense	probably benign	0.00
PIT4403001:Ahnak	UTSW	19	8,983,540 (GRCm39)	missense	possibly damaging	0.87
R0054:Ahnak	UTSW	19	8,989,420 (GRCm39)	missense	probably damaging	1.00
R0094:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R0110:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0141:Ahnak	UTSW	19	8,984,044 (GRCm39)	missense	probably damaging	1.00
R0166:Ahnak	UTSW	19	8,983,089 (GRCm39)	missense	probably damaging	1.00
R0309:Ahnak	UTSW	19	8,979,859 (GRCm39)	missense	probably damaging	1.00
R0368:Ahnak	UTSW	19	8,985,714 (GRCm39)	nonsense	probably null
R0386:Ahnak	UTSW	19	8,988,508 (GRCm39)	missense	possibly damaging	0.94
R0401:Ahnak	UTSW	19	8,992,480 (GRCm39)	missense	probably benign	0.24
R0415:Ahnak	UTSW	19	8,990,235 (GRCm39)	intron	probably benign
R0463:Ahnak	UTSW	19	8,986,771 (GRCm39)	intron	probably benign
R0469:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0470:Ahnak	UTSW	19	8,986,331 (GRCm39)	missense	probably benign	0.29
R0487:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R0487:Ahnak	UTSW	19	8,984,515 (GRCm39)	missense	probably benign	0.00
R0499:Ahnak	UTSW	19	8,977,628 (GRCm39)	splice site	probably benign
R0506:Ahnak	UTSW	19	8,986,492 (GRCm39)	missense	probably damaging	1.00
R0510:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0557:Ahnak	UTSW	19	8,979,308 (GRCm39)	missense	probably benign	0.10
R0570:Ahnak	UTSW	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
R0610:Ahnak	UTSW	19	8,985,242 (GRCm39)	missense	probably benign	0.08
R0646:Ahnak	UTSW	19	8,990,766 (GRCm39)	nonsense	probably null
R0659:Ahnak	UTSW	19	8,992,366 (GRCm39)	missense	possibly damaging	0.60
R0791:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0792:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0840:Ahnak	UTSW	19	8,982,427 (GRCm39)	missense	probably damaging	1.00
R0847:Ahnak	UTSW	19	8,983,797 (GRCm39)	nonsense	probably null
R0941:Ahnak	UTSW	19	8,987,278 (GRCm39)	missense	probably damaging	1.00
R0962:Ahnak	UTSW	19	8,990,212 (GRCm39)	intron	probably benign
R1017:Ahnak	UTSW	19	8,987,907 (GRCm39)	missense	probably damaging	0.99
R1037:Ahnak	UTSW	19	8,984,982 (GRCm39)	missense	probably benign	0.27
R1085:Ahnak	UTSW	19	8,990,489 (GRCm39)	missense	possibly damaging	0.50
R1113:Ahnak	UTSW	19	8,982,984 (GRCm39)	missense	probably benign	0.29
R1140:Ahnak	UTSW	19	8,981,609 (GRCm39)	missense	probably damaging	1.00
R1158:Ahnak	UTSW	19	8,991,290 (GRCm39)	missense	probably benign	0.00
R1218:Ahnak	UTSW	19	8,992,983 (GRCm39)	missense	probably damaging	1.00
R1225:Ahnak	UTSW	19	8,980,247 (GRCm39)	missense	probably damaging	1.00
R1245:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R1421:Ahnak	UTSW	19	8,992,995 (GRCm39)	missense	possibly damaging	0.95
R1447:Ahnak	UTSW	19	8,984,446 (GRCm39)	missense	probably damaging	0.98
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1471:Ahnak	UTSW	19	8,990,296 (GRCm39)	intron	probably benign
R1507:Ahnak	UTSW	19	8,987,441 (GRCm39)	missense	probably damaging	1.00
R1521:Ahnak	UTSW	19	8,982,092 (GRCm39)	missense	probably benign	0.11
R1568:Ahnak	UTSW	19	8,979,739 (GRCm39)	missense	probably damaging	0.98
R1569:Ahnak	UTSW	19	8,981,458 (GRCm39)	missense	possibly damaging	0.78
R1616:Ahnak	UTSW	19	8,986,351 (GRCm39)	missense	possibly damaging	0.94
R1638:Ahnak	UTSW	19	8,986,813 (GRCm39)	missense	probably benign	0.01
R1680:Ahnak	UTSW	19	8,987,327 (GRCm39)	missense	probably benign	0.05
R1713:Ahnak	UTSW	19	8,989,173 (GRCm39)	missense	possibly damaging	0.95
R1722:Ahnak	UTSW	19	8,988,019 (GRCm39)	missense	probably damaging	0.99
R1771:Ahnak	UTSW	19	8,991,117 (GRCm39)	missense	probably benign	0.24
R1795:Ahnak	UTSW	19	8,979,802 (GRCm39)	missense	possibly damaging	0.79
R1823:Ahnak	UTSW	19	8,982,269 (GRCm39)	missense	probably damaging	0.99
R1842:Ahnak	UTSW	19	8,983,231 (GRCm39)	missense	probably damaging	0.99
R1854:Ahnak	UTSW	19	8,991,196 (GRCm39)	missense	possibly damaging	0.61
R1856:Ahnak	UTSW	19	8,979,412 (GRCm39)	missense	possibly damaging	0.86
R1886:Ahnak	UTSW	19	8,993,343 (GRCm39)	missense	probably damaging	0.98
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1912:Ahnak	UTSW	19	8,995,245 (GRCm39)	missense	probably damaging	1.00
R1913:Ahnak	UTSW	19	8,985,286 (GRCm39)	missense	probably damaging	0.99
R1942:Ahnak	UTSW	19	8,992,447 (GRCm39)	missense	probably damaging	0.98
R1987:Ahnak	UTSW	19	8,992,615 (GRCm39)	missense	probably damaging	1.00
R2006:Ahnak	UTSW	19	8,984,439 (GRCm39)	missense	probably damaging	1.00
R2013:Ahnak	UTSW	19	8,991,937 (GRCm39)	missense	probably damaging	0.98
R2014:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R2047:Ahnak	UTSW	19	8,991,664 (GRCm39)	missense	possibly damaging	0.67
R2048:Ahnak	UTSW	19	8,984,420 (GRCm39)	missense	probably damaging	0.99
R2060:Ahnak	UTSW	19	8,985,405 (GRCm39)	missense	probably benign	0.08
R2083:Ahnak	UTSW	19	8,988,921 (GRCm39)	missense	probably damaging	1.00
R2157:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R2167:Ahnak	UTSW	19	8,988,858 (GRCm39)	nonsense	probably null
R2208:Ahnak	UTSW	19	8,995,096 (GRCm39)	missense	probably benign	0.00
R2224:Ahnak	UTSW	19	8,990,355 (GRCm39)	intron	probably benign
R2268:Ahnak	UTSW	19	8,987,938 (GRCm39)	missense	possibly damaging	0.66
R2420:Ahnak	UTSW	19	8,986,620 (GRCm39)	missense	possibly damaging	0.89
R2426:Ahnak	UTSW	19	8,980,215 (GRCm39)	missense	possibly damaging	0.81
R2910:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2911:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2981:Ahnak	UTSW	19	8,977,512 (GRCm39)	missense	probably damaging	0.97
R3151:Ahnak	UTSW	19	8,987,308 (GRCm39)	missense	probably benign	0.12
R3155:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R3422:Ahnak	UTSW	19	8,984,116 (GRCm39)	missense	probably benign	0.05
R3422:Ahnak	UTSW	19	8,983,072 (GRCm39)	missense	probably benign	0.39
R3430:Ahnak	UTSW	19	8,984,322 (GRCm39)	missense	probably benign	0.42
R3433:Ahnak	UTSW	19	8,987,358 (GRCm39)	missense	probably benign	0.01
R3711:Ahnak	UTSW	19	8,985,262 (GRCm39)	missense	probably benign
R3723:Ahnak	UTSW	19	8,994,217 (GRCm39)	missense	possibly damaging	0.79
R3775:Ahnak	UTSW	19	8,986,387 (GRCm39)	missense	possibly damaging	0.91
R3858:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3859:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3922:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3924:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3926:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R4026:Ahnak	UTSW	19	8,988,663 (GRCm39)	missense	probably damaging	0.97
R4051:Ahnak	UTSW	19	8,991,691 (GRCm39)	missense	probably damaging	1.00
R4209:Ahnak	UTSW	19	8,979,964 (GRCm39)	missense	probably damaging	1.00
R4234:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R4237:Ahnak	UTSW	19	8,979,147 (GRCm39)	missense	probably benign	0.02
R4285:Ahnak	UTSW	19	8,994,203 (GRCm39)	nonsense	probably null
R4331:Ahnak	UTSW	19	8,993,184 (GRCm39)	missense	probably damaging	1.00
R4342:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R4430:Ahnak	UTSW	19	8,980,404 (GRCm39)	missense	probably benign	0.00
R4554:Ahnak	UTSW	19	8,992,294 (GRCm39)	missense	probably damaging	1.00
R4602:Ahnak	UTSW	19	8,988,189 (GRCm39)	missense	possibly damaging	0.66
R4612:Ahnak	UTSW	19	8,981,088 (GRCm39)	missense	probably benign	0.44
R4655:Ahnak	UTSW	19	8,986,065 (GRCm39)	missense	probably damaging	1.00
R4656:Ahnak	UTSW	19	8,982,219 (GRCm39)	missense	possibly damaging	0.80
R4700:Ahnak	UTSW	19	8,982,045 (GRCm39)	missense	probably benign	0.02
R4704:Ahnak	UTSW	19	8,989,622 (GRCm39)	intron	probably benign
R4704:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R4705:Ahnak	UTSW	19	8,994,270 (GRCm39)	missense	probably benign	0.07
R4707:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	probably benign	0.03
R4732:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4733:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4778:Ahnak	UTSW	19	8,989,339 (GRCm39)	missense	possibly damaging	0.79
R4782:Ahnak	UTSW	19	8,989,863 (GRCm39)	intron	probably benign
R4832:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R4882:Ahnak	UTSW	19	8,983,261 (GRCm39)	missense	probably damaging	0.98
R4884:Ahnak	UTSW	19	8,990,118 (GRCm39)	intron	probably benign
R4895:Ahnak	UTSW	19	8,994,805 (GRCm39)	missense	probably benign	0.43
R4930:Ahnak	UTSW	19	8,988,331 (GRCm39)	missense	possibly damaging	0.79
R4951:Ahnak	UTSW	19	8,995,199 (GRCm39)	missense	probably damaging	1.00
R4968:Ahnak	UTSW	19	8,992,464 (GRCm39)	missense	probably damaging	1.00
R5026:Ahnak	UTSW	19	8,987,995 (GRCm39)	missense	possibly damaging	0.46
R5050:Ahnak	UTSW	19	8,989,822 (GRCm39)	intron	probably benign
R5073:Ahnak	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
R5110:Ahnak	UTSW	19	8,992,123 (GRCm39)	missense	probably damaging	1.00
R5119:Ahnak	UTSW	19	8,991,008 (GRCm39)	missense	probably benign	0.00
R5128:Ahnak	UTSW	19	8,994,451 (GRCm39)	missense	probably damaging	1.00
R5139:Ahnak	UTSW	19	8,982,019 (GRCm39)	missense	probably damaging	1.00
R5150:Ahnak	UTSW	19	8,988,268 (GRCm39)	missense	possibly damaging	0.46
R5151:Ahnak	UTSW	19	8,994,933 (GRCm39)	missense	probably benign	0.03
R5165:Ahnak	UTSW	19	8,993,029 (GRCm39)	missense	possibly damaging	0.95
R5236:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R5361:Ahnak	UTSW	19	8,992,705 (GRCm39)	missense	possibly damaging	0.92
R5366:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	possibly damaging	0.65
R5387:Ahnak	UTSW	19	8,981,055 (GRCm39)	missense	probably damaging	1.00
R5396:Ahnak	UTSW	19	8,984,539 (GRCm39)	missense	probably damaging	0.99
R5583:Ahnak	UTSW	19	8,984,281 (GRCm39)	missense	probably damaging	0.99
R5587:Ahnak	UTSW	19	8,986,840 (GRCm39)	missense	possibly damaging	0.88
R5620:Ahnak	UTSW	19	8,990,458 (GRCm39)	nonsense	probably null
R5643:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5644:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5657:Ahnak	UTSW	19	8,991,979 (GRCm39)	missense	probably damaging	0.99
R5688:Ahnak	UTSW	19	8,979,883 (GRCm39)	missense	probably benign	0.01
R5702:Ahnak	UTSW	19	8,979,204 (GRCm39)	missense	probably damaging	1.00
R5727:Ahnak	UTSW	19	8,994,111 (GRCm39)	missense	probably damaging	0.99
R5730:Ahnak	UTSW	19	8,987,617 (GRCm39)	missense	possibly damaging	0.81
R5755:Ahnak	UTSW	19	8,979,096 (GRCm39)	missense	probably benign	0.06
R5760:Ahnak	UTSW	19	8,990,926 (GRCm39)	missense	probably damaging	1.00
R5789:Ahnak	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
R5790:Ahnak	UTSW	19	8,992,612 (GRCm39)	missense	probably damaging	0.99
R5795:Ahnak	UTSW	19	8,989,746 (GRCm39)	nonsense	probably null
R5808:Ahnak	UTSW	19	8,987,599 (GRCm39)	missense	possibly damaging	0.91
R5867:Ahnak	UTSW	19	8,987,416 (GRCm39)	missense	probably damaging	0.99
R5878:Ahnak	UTSW	19	8,985,706 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,995,575 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,991,131 (GRCm39)	missense	possibly damaging	0.63
R5912:Ahnak	UTSW	19	8,989,267 (GRCm39)	missense	probably damaging	0.99
R5935:Ahnak	UTSW	19	8,992,546 (GRCm39)	missense	possibly damaging	0.91
R5969:Ahnak	UTSW	19	8,993,949 (GRCm39)	missense	probably damaging	1.00
R5988:Ahnak	UTSW	19	8,986,711 (GRCm39)	intron	probably benign
R6000:Ahnak	UTSW	19	8,990,475 (GRCm39)	nonsense	probably null
R6005:Ahnak	UTSW	19	8,992,525 (GRCm39)	missense	possibly damaging	0.61
R6101:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6105:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6116:Ahnak	UTSW	19	8,990,327 (GRCm39)	intron	probably benign
R6209:Ahnak	UTSW	19	8,989,930 (GRCm39)	missense	probably damaging	1.00
R6240:Ahnak	UTSW	19	8,990,947 (GRCm39)	missense	probably damaging	1.00
R6255:Ahnak	UTSW	19	8,985,389 (GRCm39)	missense	possibly damaging	0.95
R6263:Ahnak	UTSW	19	8,995,641 (GRCm39)	missense	probably benign	0.03
R6287:Ahnak	UTSW	19	8,992,367 (GRCm39)	missense	probably benign	0.02
R6296:Ahnak	UTSW	19	8,980,669 (GRCm39)	missense	probably damaging	0.99
R6315:Ahnak	UTSW	19	8,983,990 (GRCm39)	missense	probably damaging	0.99
R6328:Ahnak	UTSW	19	8,984,512 (GRCm39)	missense	probably benign	0.11
R6331:Ahnak	UTSW	19	8,983,989 (GRCm39)	missense	probably benign	0.18
R6355:Ahnak	UTSW	19	8,986,126 (GRCm39)	missense	probably benign	0.02
R6409:Ahnak	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
R6567:Ahnak	UTSW	19	8,986,170 (GRCm39)	missense	probably benign	0.27
R6574:Ahnak	UTSW	19	8,994,411 (GRCm39)	missense	probably benign	0.04
R6590:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6620:Ahnak	UTSW	19	8,992,674 (GRCm39)	missense	possibly damaging	0.95
R6690:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6731:Ahnak	UTSW	19	8,988,926 (GRCm39)	missense	possibly damaging	0.85
R6756:Ahnak	UTSW	19	8,984,925 (GRCm39)	missense	possibly damaging	0.59
R6846:Ahnak	UTSW	19	8,989,221 (GRCm39)	missense	possibly damaging	0.66
R6854:Ahnak	UTSW	19	8,992,599 (GRCm39)	missense	probably damaging	1.00
R6857:Ahnak	UTSW	19	9,014,532 (GRCm39)	nonsense	probably null
R6863:Ahnak	UTSW	19	8,989,729 (GRCm39)	intron	probably benign
R6876:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R6958:Ahnak	UTSW	19	8,992,579 (GRCm39)	missense	possibly damaging	0.88
R7126:Ahnak	UTSW	19	8,979,723 (GRCm39)	missense	possibly damaging	0.61
R7181:Ahnak	UTSW	19	8,990,852 (GRCm39)	missense	probably damaging	1.00
R7183:Ahnak	UTSW	19	8,995,032 (GRCm39)	missense	probably damaging	1.00
R7202:Ahnak	UTSW	19	8,995,163 (GRCm39)	missense	probably damaging	1.00
R7235:Ahnak	UTSW	19	8,989,852 (GRCm39)	missense	unknown
R7241:Ahnak	UTSW	19	8,986,395 (GRCm39)	missense	possibly damaging	0.65
R7269:Ahnak	UTSW	19	8,983,981 (GRCm39)	missense	probably damaging	1.00
R7311:Ahnak	UTSW	19	8,979,507 (GRCm39)	missense	probably benign	0.04
R7311:Ahnak	UTSW	19	8,987,191 (GRCm39)	missense	possibly damaging	0.56
R7329:Ahnak	UTSW	19	8,979,156 (GRCm39)	missense	probably damaging	0.99
R7339:Ahnak	UTSW	19	8,985,529 (GRCm39)	missense	possibly damaging	0.75
R7390:Ahnak	UTSW	19	8,980,569 (GRCm39)	missense	probably benign	0.02
R7400:Ahnak	UTSW	19	8,991,977 (GRCm39)	missense	probably damaging	0.99
R7444:Ahnak	UTSW	19	8,984,787 (GRCm39)	missense	probably benign	0.08
R7483:Ahnak	UTSW	19	8,982,186 (GRCm39)	missense	probably damaging	1.00
R7498:Ahnak	UTSW	19	8,989,383 (GRCm39)	missense	probably benign	0.14
R7521:Ahnak	UTSW	19	8,979,715 (GRCm39)	missense	possibly damaging	0.89
R7522:Ahnak	UTSW	19	8,979,686 (GRCm39)	missense	probably benign	0.01
R7552:Ahnak	UTSW	19	8,984,188 (GRCm39)	missense	probably benign	0.18
R7563:Ahnak	UTSW	19	8,988,529 (GRCm39)	missense	probably damaging	0.99
R7565:Ahnak	UTSW	19	8,993,520 (GRCm39)	missense	probably benign	0.05
R7571:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R7583:Ahnak	UTSW	19	8,983,457 (GRCm39)	missense	possibly damaging	0.90
R7600:Ahnak	UTSW	19	8,981,938 (GRCm39)	missense	possibly damaging	0.89
R7771:Ahnak	UTSW	19	8,992,411 (GRCm39)	missense	probably damaging	0.99
R7787:Ahnak	UTSW	19	8,986,679 (GRCm39)	missense	unknown
R7827:Ahnak	UTSW	19	8,982,708 (GRCm39)	nonsense	probably null
R7857:Ahnak	UTSW	19	8,984,832 (GRCm39)	missense	probably damaging	0.97
R7916:Ahnak	UTSW	19	8,983,196 (GRCm39)	missense	possibly damaging	0.66
R7939:Ahnak	UTSW	19	8,991,448 (GRCm39)	nonsense	probably null
R7959:Ahnak	UTSW	19	8,988,013 (GRCm39)	missense	possibly damaging	0.46
R7962:Ahnak	UTSW	19	8,990,164 (GRCm39)	missense	unknown
R7979:Ahnak	UTSW	19	8,988,796 (GRCm39)	missense	probably damaging	1.00
R8006:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R8013:Ahnak	UTSW	19	8,986,699 (GRCm39)	missense	unknown
R8033:Ahnak	UTSW	19	8,981,074 (GRCm39)	missense	probably benign	0.10
R8124:Ahnak	UTSW	19	8,984,487 (GRCm39)	missense	probably damaging	0.99
R8125:Ahnak	UTSW	19	8,989,240 (GRCm39)	missense	possibly damaging	0.95
R8129:Ahnak	UTSW	19	8,977,464 (GRCm39)	start codon destroyed	not run
R8151:Ahnak	UTSW	19	8,982,043 (GRCm39)	missense	possibly damaging	0.59
R8190:Ahnak	UTSW	19	8,979,619 (GRCm39)	missense	probably benign	0.01
R8221:Ahnak	UTSW	19	8,987,800 (GRCm39)	nonsense	probably null
R8241:Ahnak	UTSW	19	8,984,659 (GRCm39)	missense	probably benign	0.15
R8244:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8248:Ahnak	UTSW	19	8,979,310 (GRCm39)	missense	probably damaging	1.00
R8261:Ahnak	UTSW	19	8,982,817 (GRCm39)	missense	probably damaging	1.00
R8330:Ahnak	UTSW	19	8,987,026 (GRCm39)	missense	possibly damaging	0.86
R8380:Ahnak	UTSW	19	8,995,219 (GRCm39)	missense	probably benign	0.05
R8407:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8409:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8463:Ahnak	UTSW	19	8,986,113 (GRCm39)	missense	probably benign	0.07
R8511:Ahnak	UTSW	19	8,989,719 (GRCm39)	missense	unknown
R8528:Ahnak	UTSW	19	8,985,092 (GRCm39)	missense	probably damaging	1.00
R8549:Ahnak	UTSW	19	8,988,847 (GRCm39)	missense	probably damaging	1.00
R8674:Ahnak	UTSW	19	8,983,360 (GRCm39)	missense	probably damaging	0.98
R8716:Ahnak	UTSW	19	8,986,438 (GRCm39)	missense	probably damaging	1.00
R8722:Ahnak	UTSW	19	8,990,710 (GRCm39)	nonsense	probably null
R8751:Ahnak	UTSW	19	8,987,509 (GRCm39)	missense	probably damaging	1.00
R8752:Ahnak	UTSW	19	8,992,901 (GRCm39)	missense	probably damaging	1.00
R8783:Ahnak	UTSW	19	8,988,837 (GRCm39)	missense	probably damaging	1.00
R8844:Ahnak	UTSW	19	8,984,254 (GRCm39)	missense	probably damaging	1.00
R8859:Ahnak	UTSW	19	8,984,567 (GRCm39)	missense	probably damaging	1.00
R8882:Ahnak	UTSW	19	8,978,106 (GRCm39)	missense	probably damaging	1.00
R8907:Ahnak	UTSW	19	8,986,452 (GRCm39)	missense	probably benign	0.24
R8938:Ahnak	UTSW	19	8,989,099 (GRCm39)	missense	probably benign	0.00
R8975:Ahnak	UTSW	19	8,990,101 (GRCm39)	missense	probably damaging	1.00
R8983:Ahnak	UTSW	19	8,981,477 (GRCm39)	missense	possibly damaging	0.75
R9017:Ahnak	UTSW	19	8,987,487 (GRCm39)	missense	probably damaging	1.00
R9027:Ahnak	UTSW	19	8,984,617 (GRCm39)	missense	possibly damaging	0.94
R9081:Ahnak	UTSW	19	8,985,890 (GRCm39)	missense	possibly damaging	0.81
R9104:Ahnak	UTSW	19	8,987,711 (GRCm39)	missense	probably benign	0.01
R9112:Ahnak	UTSW	19	8,987,149 (GRCm39)	missense	probably damaging	0.98
R9145:Ahnak	UTSW	19	8,992,287 (GRCm39)	missense	probably benign	0.38
R9189:Ahnak	UTSW	19	8,988,247 (GRCm39)	missense	possibly damaging	0.92
R9221:Ahnak	UTSW	19	8,989,943 (GRCm39)	missense	probably damaging	1.00
R9261:Ahnak	UTSW	19	8,993,503 (GRCm39)	missense	possibly damaging	0.63
R9299:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9325:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R9337:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9340:Ahnak	UTSW	19	8,994,411 (GRCm39)	missense	probably benign	0.04
R9351:Ahnak	UTSW	19	8,985,232 (GRCm39)	missense	probably damaging	1.00
R9416:Ahnak	UTSW	19	8,990,266 (GRCm39)	missense	unknown
R9462:Ahnak	UTSW	19	8,981,299 (GRCm39)	missense	probably damaging	0.96
R9469:Ahnak	UTSW	19	8,988,225 (GRCm39)	missense	probably damaging	1.00
R9485:Ahnak	UTSW	19	8,979,438 (GRCm39)	missense	probably benign	0.16
R9503:Ahnak	UTSW	19	8,987,458 (GRCm39)	missense	probably damaging	1.00
R9524:Ahnak	UTSW	19	9,014,617 (GRCm39)	missense
R9534:Ahnak	UTSW	19	8,980,976 (GRCm39)	missense	probably benign	0.20
R9598:Ahnak	UTSW	19	8,981,149 (GRCm39)	missense	probably benign	0.42
R9611:Ahnak	UTSW	19	8,989,162 (GRCm39)	missense	probably damaging	0.99
R9624:Ahnak	UTSW	19	8,989,846 (GRCm39)	missense	unknown
R9649:Ahnak	UTSW	19	8,985,786 (GRCm39)	nonsense	probably null
R9683:Ahnak	UTSW	19	8,984,719 (GRCm39)	missense	possibly damaging	0.94
R9691:Ahnak	UTSW	19	8,989,090 (GRCm39)	missense	possibly damaging	0.49
R9712:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9712:Ahnak	UTSW	19	8,984,392 (GRCm39)	small deletion	probably benign
R9713:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9715:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9725:Ahnak	UTSW	19	8,991,607 (GRCm39)	missense	probably damaging	1.00
R9725:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R9747:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R9798:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
RF007:Ahnak	UTSW	19	8,990,965 (GRCm39)	missense	possibly damaging	0.45
X0021:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
X0027:Ahnak	UTSW	19	8,989,401 (GRCm39)	missense	probably damaging	1.00
Z1088:Ahnak	UTSW	19	8,993,446 (GRCm39)	missense	probably damaging	0.99
Z1176:Ahnak	UTSW	19	8,986,220 (GRCm39)	missense	probably damaging	0.97
Z1177:Ahnak	UTSW	19	8,994,832 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TGAAAGGCCCCAAGTTCAAG -3'
(R):5'- AATTTGGGGCCCTTCAGCTTC -3'

Sequencing Primer
(F):5'- GTTCAAGATGCCTGACATGC -3'
(R):5'- TGGAACATCAATGTCCACCTTGG -3'

Posted On

2018-06-22