Incidental Mutation 'IGL01088:Zfp820'
| ID |
53039 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp820
|
| Ensembl Gene |
ENSMUSG00000069743 |
| Gene Name |
zinc finger protein 820 |
| Synonyms |
2610036F08Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.130)
|
| Stock # |
IGL01088
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
22035857-22064740 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 22040162 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Stop codon
at position 16
(K16*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000081158
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000084141]
|
| AlphaFold |
A0A3B2W7H5 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000084141
AA Change: K16*
|
| SMART Domains |
Protein: ENSMUSP00000081158
Gene: ENSMUSG00000069743
AA Change: K16*
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
13 |
73 |
8.77e-20 |
SMART |
|
ZnF_C2H2
|
183 |
205 |
6.32e-3 |
SMART |
|
ZnF_C2H2
|
211 |
233 |
2.79e-4 |
SMART |
|
ZnF_C2H2
|
239 |
261 |
4.3e-5 |
SMART |
|
ZnF_C2H2
|
267 |
289 |
4.61e-5 |
SMART |
|
ZnF_C2H2
|
295 |
317 |
1.2e-3 |
SMART |
|
ZnF_C2H2
|
323 |
345 |
1.22e-4 |
SMART |
|
ZnF_C2H2
|
351 |
373 |
2.75e-3 |
SMART |
|
ZnF_C2H2
|
379 |
401 |
2.95e-3 |
SMART |
|
ZnF_C2H2
|
407 |
429 |
5.29e-5 |
SMART |
|
ZnF_C2H2
|
435 |
457 |
1.42e-5 |
SMART |
|
ZnF_C2H2
|
463 |
485 |
1.2e-3 |
SMART |
|
ZnF_C2H2
|
491 |
513 |
1.13e-4 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 32 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actr6 |
C |
T |
10: 89,561,703 (GRCm39) |
V148I |
probably damaging |
Het |
| Aspn |
G |
T |
13: 49,720,029 (GRCm39) |
K348N |
probably benign |
Het |
| C1qtnf9 |
T |
C |
14: 61,017,205 (GRCm39) |
V245A |
probably benign |
Het |
| Cfhr4 |
T |
C |
1: 139,625,823 (GRCm39) |
|
probably benign |
Het |
| Chd4 |
T |
C |
6: 125,099,431 (GRCm39) |
|
probably benign |
Het |
| Clcn3 |
A |
T |
8: 61,390,381 (GRCm39) |
C187S |
probably damaging |
Het |
| Dcxr |
T |
C |
11: 120,616,993 (GRCm39) |
I123M |
possibly damaging |
Het |
| Fstl1 |
T |
C |
16: 37,647,175 (GRCm39) |
Y182H |
probably damaging |
Het |
| Ghrhr |
T |
C |
6: 55,356,178 (GRCm39) |
|
probably null |
Het |
| Gpr179 |
T |
C |
11: 97,228,627 (GRCm39) |
E1176G |
probably damaging |
Het |
| H2-T22 |
A |
G |
17: 36,352,811 (GRCm39) |
S99P |
probably damaging |
Het |
| Igkv4-79 |
T |
A |
6: 69,020,110 (GRCm39) |
K68N |
probably damaging |
Het |
| Kpna6 |
C |
T |
4: 129,549,276 (GRCm39) |
V169I |
probably damaging |
Het |
| Krit1 |
G |
T |
5: 3,862,844 (GRCm39) |
V278F |
probably damaging |
Het |
| Mrpl4 |
T |
C |
9: 20,914,627 (GRCm39) |
S68P |
probably damaging |
Het |
| Mylk3 |
A |
C |
8: 86,078,586 (GRCm39) |
|
probably null |
Het |
| Nfasc |
A |
T |
1: 132,570,514 (GRCm39) |
|
probably benign |
Het |
| Ntsr1 |
T |
C |
2: 180,184,335 (GRCm39) |
F346S |
probably damaging |
Het |
| Or10ak11 |
A |
G |
4: 118,686,989 (GRCm39) |
V216A |
probably benign |
Het |
| Or5b107 |
T |
C |
19: 13,142,735 (GRCm39) |
M119T |
probably damaging |
Het |
| Phox2a |
T |
C |
7: 101,470,942 (GRCm39) |
F145L |
probably damaging |
Het |
| Rbm7 |
A |
G |
9: 48,402,149 (GRCm39) |
V146A |
probably damaging |
Het |
| Sall3 |
A |
T |
18: 81,016,447 (GRCm39) |
Y494N |
probably damaging |
Het |
| Ssbp1 |
T |
A |
6: 40,455,004 (GRCm39) |
|
probably benign |
Het |
| Stard7 |
T |
C |
2: 127,112,746 (GRCm39) |
L4P |
probably damaging |
Het |
| Stk-ps2 |
A |
T |
1: 46,069,010 (GRCm39) |
|
noncoding transcript |
Het |
| Tmem67 |
G |
A |
4: 12,063,126 (GRCm39) |
R507C |
probably damaging |
Het |
| Unc13c |
A |
T |
9: 73,839,563 (GRCm39) |
D429E |
possibly damaging |
Het |
| Unc93b1 |
A |
G |
19: 3,985,356 (GRCm39) |
|
probably null |
Het |
| Vmn1r171 |
T |
C |
7: 23,332,252 (GRCm39) |
V159A |
probably damaging |
Het |
| Zfp608 |
T |
C |
18: 55,031,159 (GRCm39) |
E927G |
probably benign |
Het |
| Zgrf1 |
T |
C |
3: 127,381,790 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Zfp820 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00424:Zfp820
|
APN |
17 |
22,038,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00954:Zfp820
|
APN |
17 |
22,038,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03067:Zfp820
|
APN |
17 |
22,038,801 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0158:Zfp820
|
UTSW |
17 |
22,038,800 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0617:Zfp820
|
UTSW |
17 |
22,038,685 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0658:Zfp820
|
UTSW |
17 |
22,037,901 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0696:Zfp820
|
UTSW |
17 |
22,039,041 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0791:Zfp820
|
UTSW |
17 |
22,038,509 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0792:Zfp820
|
UTSW |
17 |
22,038,509 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0882:Zfp820
|
UTSW |
17 |
22,042,817 (GRCm39) |
splice site |
probably benign |
|
|
R1421:Zfp820
|
UTSW |
17 |
22,038,861 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1573:Zfp820
|
UTSW |
17 |
22,037,737 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1928:Zfp820
|
UTSW |
17 |
22,038,316 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3889:Zfp820
|
UTSW |
17 |
22,037,877 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4782:Zfp820
|
UTSW |
17 |
22,037,966 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4799:Zfp820
|
UTSW |
17 |
22,037,966 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4807:Zfp820
|
UTSW |
17 |
22,042,853 (GRCm39) |
start codon destroyed |
probably null |
1.00 |
|
R4913:Zfp820
|
UTSW |
17 |
22,038,200 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5100:Zfp820
|
UTSW |
17 |
22,040,054 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R5766:Zfp820
|
UTSW |
17 |
22,038,983 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5772:Zfp820
|
UTSW |
17 |
22,037,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6516:Zfp820
|
UTSW |
17 |
22,038,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6577:Zfp820
|
UTSW |
17 |
22,038,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7094:Zfp820
|
UTSW |
17 |
22,038,246 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7570:Zfp820
|
UTSW |
17 |
22,037,994 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7794:Zfp820
|
UTSW |
17 |
22,039,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8545:Zfp820
|
UTSW |
17 |
22,038,438 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8692:Zfp820
|
UTSW |
17 |
22,037,876 (GRCm39) |
missense |
probably benign |
0.43 |
|
R9072:Zfp820
|
UTSW |
17 |
22,039,031 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9073:Zfp820
|
UTSW |
17 |
22,039,031 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9325:Zfp820
|
UTSW |
17 |
22,038,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9421:Zfp820
|
UTSW |
17 |
22,038,336 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9480:Zfp820
|
UTSW |
17 |
22,037,994 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9592:Zfp820
|
UTSW |
17 |
22,038,577 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9600:Zfp820
|
UTSW |
17 |
22,038,861 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9632:Zfp820
|
UTSW |
17 |
22,038,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2013-06-21 |
Incidental Mutation