Incidental Mutation 'IGL01093:Vmn1r225'
| ID |
53049 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r225
|
| Ensembl Gene |
ENSMUSG00000043537 |
| Gene Name |
vomeronasal 1 receptor 225 |
| Synonyms |
V1re5 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.066)
|
| Stock # |
IGL01093
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
17 |
| Chromosomal Location |
20722561-20723457 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 20723081 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 174
(D174V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000056068
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061660]
|
| AlphaFold |
Q8R2A5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000061660
AA Change: D174V
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000056068
Gene: ENSMUSG00000043537
AA Change: D174V
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
1 |
287 |
8.9e-15 |
PFAM |
|
Pfam:V1R
|
11 |
291 |
3.1e-24 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 29 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Akr1c21 |
C |
T |
13: 4,631,139 (GRCm39) |
|
probably benign |
Het |
| Alpk2 |
A |
G |
18: 65,482,400 (GRCm39) |
L69P |
probably damaging |
Het |
| C3 |
G |
T |
17: 57,530,949 (GRCm39) |
P384Q |
probably damaging |
Het |
| Cobll1 |
T |
C |
2: 64,928,581 (GRCm39) |
E953G |
probably damaging |
Het |
| Dnaaf9 |
T |
C |
2: 130,619,156 (GRCm39) |
T281A |
probably benign |
Het |
| Dnmt1 |
C |
T |
9: 20,821,081 (GRCm39) |
E1269K |
possibly damaging |
Het |
| Dync2h1 |
T |
C |
9: 7,145,611 (GRCm39) |
R1012G |
probably benign |
Het |
| Fbxw24 |
T |
A |
9: 109,434,041 (GRCm39) |
Q423L |
probably benign |
Het |
| Flg2 |
T |
C |
3: 93,109,678 (GRCm39) |
S569P |
unknown |
Het |
| Ier5 |
A |
G |
1: 154,975,139 (GRCm39) |
I13T |
probably damaging |
Het |
| Kat6a |
A |
G |
8: 23,429,337 (GRCm39) |
D1564G |
possibly damaging |
Het |
| Lcn5 |
T |
C |
2: 25,550,729 (GRCm39) |
V139A |
probably benign |
Het |
| Naca |
A |
G |
10: 127,883,982 (GRCm39) |
S2138G |
probably damaging |
Het |
| Or1j15 |
T |
G |
2: 36,458,838 (GRCm39) |
V76G |
probably damaging |
Het |
| Or5p59 |
T |
A |
7: 107,702,851 (GRCm39) |
S112T |
probably benign |
Het |
| Or5w14 |
T |
G |
2: 87,541,477 (GRCm39) |
M258L |
possibly damaging |
Het |
| Or6c66 |
A |
C |
10: 129,461,432 (GRCm39) |
F166C |
probably damaging |
Het |
| Or6c74 |
A |
G |
10: 129,869,761 (GRCm39) |
T89A |
probably benign |
Het |
| Pcdhgb8 |
A |
G |
18: 37,958,089 (GRCm39) |
T813A |
probably damaging |
Het |
| Pkd1l1 |
T |
C |
11: 8,851,345 (GRCm39) |
T696A |
probably benign |
Het |
| Rif1 |
T |
G |
2: 51,985,960 (GRCm39) |
H648Q |
probably damaging |
Het |
| Secisbp2l |
C |
A |
2: 125,582,245 (GRCm39) |
K1070N |
probably benign |
Het |
| Spock3 |
G |
A |
8: 63,801,993 (GRCm39) |
R327Q |
probably benign |
Het |
| Trpm2 |
A |
G |
10: 77,768,114 (GRCm39) |
I795T |
probably benign |
Het |
| Ube4b |
T |
C |
4: 149,414,726 (GRCm39) |
I1128V |
probably benign |
Het |
| Xpnpep3 |
T |
A |
15: 81,320,969 (GRCm39) |
Y283N |
possibly damaging |
Het |
| Zfp9 |
C |
T |
6: 118,442,800 (GRCm39) |
A99T |
probably benign |
Het |
| Zfp944 |
A |
G |
17: 22,562,615 (GRCm39) |
|
probably benign |
Het |
| Zscan4c |
G |
A |
7: 10,743,544 (GRCm39) |
C381Y |
probably benign |
Het |
|
| Other mutations in Vmn1r225 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01830:Vmn1r225
|
APN |
17 |
20,722,717 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02943:Vmn1r225
|
APN |
17 |
20,722,567 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0544:Vmn1r225
|
UTSW |
17 |
20,722,718 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1126:Vmn1r225
|
UTSW |
17 |
20,722,588 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1809:Vmn1r225
|
UTSW |
17 |
20,722,918 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1928:Vmn1r225
|
UTSW |
17 |
20,723,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2044:Vmn1r225
|
UTSW |
17 |
20,722,852 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2191:Vmn1r225
|
UTSW |
17 |
20,723,147 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2206:Vmn1r225
|
UTSW |
17 |
20,722,611 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R2207:Vmn1r225
|
UTSW |
17 |
20,722,611 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R2680:Vmn1r225
|
UTSW |
17 |
20,723,055 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3740:Vmn1r225
|
UTSW |
17 |
20,723,261 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R3807:Vmn1r225
|
UTSW |
17 |
20,723,114 (GRCm39) |
nonsense |
probably null |
|
|
R4196:Vmn1r225
|
UTSW |
17 |
20,723,237 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4970:Vmn1r225
|
UTSW |
17 |
20,722,831 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R5129:Vmn1r225
|
UTSW |
17 |
20,723,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Vmn1r225
|
UTSW |
17 |
20,723,047 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5187:Vmn1r225
|
UTSW |
17 |
20,723,177 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5580:Vmn1r225
|
UTSW |
17 |
20,723,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6563:Vmn1r225
|
UTSW |
17 |
20,722,763 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6674:Vmn1r225
|
UTSW |
17 |
20,723,377 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7003:Vmn1r225
|
UTSW |
17 |
20,723,416 (GRCm39) |
missense |
probably null |
0.01 |
|
R7143:Vmn1r225
|
UTSW |
17 |
20,722,646 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7422:Vmn1r225
|
UTSW |
17 |
20,723,059 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7651:Vmn1r225
|
UTSW |
17 |
20,722,611 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7952:Vmn1r225
|
UTSW |
17 |
20,722,589 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8097:Vmn1r225
|
UTSW |
17 |
20,722,611 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8696:Vmn1r225
|
UTSW |
17 |
20,723,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8823:Vmn1r225
|
UTSW |
17 |
20,722,823 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9007:Vmn1r225
|
UTSW |
17 |
20,723,449 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9041:Vmn1r225
|
UTSW |
17 |
20,722,577 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9147:Vmn1r225
|
UTSW |
17 |
20,722,577 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9148:Vmn1r225
|
UTSW |
17 |
20,722,577 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9312:Vmn1r225
|
UTSW |
17 |
20,722,960 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9401:Vmn1r225
|
UTSW |
17 |
20,722,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9401:Vmn1r225
|
UTSW |
17 |
20,722,911 (GRCm39) |
nonsense |
probably null |
|
|
R9488:Vmn1r225
|
UTSW |
17 |
20,722,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Vmn1r225
|
UTSW |
17 |
20,722,753 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
| Posted On |
2013-06-21 |
Incidental Mutation