Mutagenetix > Incidental Mutation

Incidental Mutation 'R6782:Ptprd'

531454

Institutional Source

Beutler Lab

Gene Symbol

Ptprd

Ensembl Gene

ENSMUSG00000028399

Gene Name

protein tyrosine phosphatase receptor type D

Synonyms

1110002J03Rik, B230219D21Rik, 3000002J10Rik

MMRRC Submission

044896-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R6782 (G1)

Quality Score

215.009

Status

Not validated

Chromosome

Chromosomal Location

75859475-78130198 bp(-) (GRCm39)

Type of Mutation

splice site (40 bp from exon)

DNA Base Change (assembly)

T to C at 76243377 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000133328 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000050757] [ENSMUST00000098005] [ENSMUST00000107289] [ENSMUST00000173376] [ENSMUST00000174023] [ENSMUST00000174180] [ENSMUST00000174531] [ENSMUST00000174831]

AlphaFold

Q64487

Predicted Effect

probably null
Transcript: ENSMUST00000050757

SMART Domains

Protein: ENSMUSP00000058466
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	208	1.38e-15	SMART
IGc2	238	299	8.13e-4	SMART
FN3	313	392	7.92e-14	SMART
FN3	408	491	5.73e-11	SMART
IG_like	499	593	8.34e1	SMART
FN3	506	584	9.1e-14	SMART
FN3	597	674	1.21e0	SMART
transmembrane domain	847	869	N/A	INTRINSIC
low complexity region	870	882	N/A	INTRINSIC
PTPc	949	1207	6.38e-134	SMART
PTPc	1236	1498	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000098005

SMART Domains

Protein: ENSMUSP00000095614
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	214	8.5e-16	SMART
low complexity region	225	237	N/A	INTRINSIC
IGc2	248	309	8.13e-4	SMART
FN3	323	402	7.92e-14	SMART
FN3	418	501	5.73e-11	SMART
IG_like	509	603	8.34e1	SMART
FN3	516	594	9.1e-14	SMART
FN3	607	684	1.21e0	SMART
transmembrane domain	857	879	N/A	INTRINSIC
low complexity region	886	897	N/A	INTRINSIC
PTPc	950	1208	6.38e-134	SMART
PTPc	1237	1499	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000107289

SMART Domains

Protein: ENSMUSP00000102910
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	214	8.5e-16	SMART
low complexity region	225	237	N/A	INTRINSIC
IGc2	248	309	8.13e-4	SMART
FN3	323	402	7.92e-14	SMART
FN3	418	501	5.73e-11	SMART
IG_like	509	603	8.34e1	SMART
FN3	516	594	9.1e-14	SMART
FN3	609	696	2.72e-12	SMART
FN3	712	809	2.87e-11	SMART
FN3	824	904	4.96e-6	SMART
FN3	919	1003	4.12e-12	SMART
FN3	1018	1095	1.95e0	SMART
transmembrane domain	1268	1290	N/A	INTRINSIC
low complexity region	1291	1303	N/A	INTRINSIC
PTPc	1356	1614	6.38e-134	SMART
PTPc	1643	1905	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000173376

SMART Domains

Protein: ENSMUSP00000133468
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	43	112	8.57e-12	SMART
IGc2	145	221	8.5e-16	SMART
low complexity region	232	244	N/A	INTRINSIC
IGc2	255	316	8.13e-4	SMART
FN3	330	409	7.92e-14	SMART
FN3	425	508	5.73e-11	SMART
IG_like	516	610	8.34e1	SMART
FN3	523	601	9.1e-14	SMART
FN3	614	691	1.21e0	SMART
transmembrane domain	864	886	N/A	INTRINSIC
low complexity region	887	899	N/A	INTRINSIC
PTPc	952	1210	6.38e-134	SMART
PTPc	1239	1501	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000174023

SMART Domains

Protein: ENSMUSP00000133562
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	211	4.88e-16	SMART
low complexity region	222	234	N/A	INTRINSIC
IGc2	245	306	8.13e-4	SMART
FN3	320	399	7.92e-14	SMART
FN3	415	498	5.73e-11	SMART
IG_like	506	600	8.34e1	SMART
FN3	513	591	9.1e-14	SMART
FN3	604	681	1.21e0	SMART
transmembrane domain	853	875	N/A	INTRINSIC
low complexity region	882	893	N/A	INTRINSIC
PTPc	946	1204	6.38e-134	SMART
PTPc	1233	1495	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000174180

SMART Domains

Protein: ENSMUSP00000133973
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	205	2.09e-15	SMART
IGc2	235	296	8.13e-4	SMART
FN3	310	389	7.92e-14	SMART
FN3	405	488	5.73e-11	SMART
IG_like	496	590	8.34e1	SMART
FN3	503	581	9.1e-14	SMART
FN3	596	683	2.72e-12	SMART
FN3	699	787	6.15e-11	SMART
FN3	802	882	4.96e-6	SMART
FN3	897	981	4.12e-12	SMART
FN3	996	1073	1.95e0	SMART
transmembrane domain	1246	1268	N/A	INTRINSIC
low complexity region	1269	1281	N/A	INTRINSIC
PTPc	1334	1592	6.38e-134	SMART
PTPc	1621	1883	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000174531

SMART Domains

Protein: ENSMUSP00000134229
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	208	1.38e-15	SMART
low complexity region	219	231	N/A	INTRINSIC
IGc2	242	303	8.13e-4	SMART
FN3	317	396	7.92e-14	SMART
FN3	412	495	5.73e-11	SMART
IG_like	503	597	8.34e1	SMART
FN3	510	588	9.1e-14	SMART
FN3	601	678	1.21e0	SMART
transmembrane domain	851	873	N/A	INTRINSIC
low complexity region	874	886	N/A	INTRINSIC
PTPc	939	1197	6.38e-134	SMART
PTPc	1226	1488	9.17e-135	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000174831

SMART Domains

Protein: ENSMUSP00000133328
Gene: ENSMUSG00000028399

Domain	Start	End	E-Value	Type
IGc2	36	105	8.57e-12	SMART
IGc2	138	214	8.5e-16	SMART
low complexity region	225	237	N/A	INTRINSIC
IGc2	248	309	8.13e-4	SMART
FN3	323	402	7.92e-14	SMART
FN3	418	501	5.73e-11	SMART
IG_like	509	603	8.34e1	SMART
FN3	516	594	9.1e-14	SMART
FN3	607	684	1.21e0	SMART
transmembrane domain	856	878	N/A	INTRINSIC
low complexity region	885	896	N/A	INTRINSIC
PTPc	949	1207	6.38e-134	SMART
PTPc	1236	1498	9.17e-135	SMART

Coding Region Coverage

1x: 99.9%
3x: 99.6%
10x: 98.4%
20x: 95.7%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Homozygotes for a targeted null mutation exhibit impaired learning of spatial tasks, enhanced long-term potentiation at hippocampal synapses, and high mortality associated with reduced food intake. [provided by MGI curators]

Allele List at MGI

All alleles(9) : Targeted(4) Gene trapped(5)

Other mutations in this stock

Total: 55 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca14	C	T	7: 119,847,308 (GRCm39)	A724V	probably damaging	Het
Abcc3	A	T	11: 94,249,776 (GRCm39)	F1055L	probably damaging	Het
Akt3	A	T	1: 176,877,756 (GRCm39)	Y337*	probably null	Het
Ankrd17	T	C	5: 90,402,597 (GRCm39)	K1488R	possibly damaging	Het
Ano1	G	A	7: 144,175,424 (GRCm39)	T498I	probably damaging	Het
Arhgap42	T	A	9: 9,115,721 (GRCm39)	K118N	probably damaging	Het
Arl5b	A	G	2: 15,077,993 (GRCm39)	E106G	probably damaging	Het
Atp5mc3	C	T	2: 73,739,672 (GRCm39)	R56Q	probably benign	Het
Bbx	T	C	16: 50,020,928 (GRCm39)	R749G	probably benign	Het
Cacna1g	A	G	11: 94,350,376 (GRCm39)	S490P	probably damaging	Het
Ccdc63	A	T	5: 122,249,077 (GRCm39)	Y417*	probably null	Het
Cep162	A	T	9: 87,093,737 (GRCm39)	N880K	probably benign	Het
Chd2	G	A	7: 73,125,127 (GRCm39)	Q77*	probably null	Het
Cntrl	T	G	2: 35,060,658 (GRCm39)	M1397R	possibly damaging	Het
Dcaf7	A	G	11: 105,945,581 (GRCm39)	Y310C	probably damaging	Het
Dnah5	T	A	15: 28,449,302 (GRCm39)	S4235T	possibly damaging	Het
Dot1l	C	T	10: 80,625,224 (GRCm39)	P1157L	probably damaging	Het
Esco2	T	C	14: 66,057,465 (GRCm39)	T577A	probably benign	Het
Foxp1	T	C	6: 98,907,106 (GRCm39)	D624G	probably damaging	Het
Gfi1	A	T	5: 107,873,819 (GRCm39)		probably null	Het
Gm10985	TTCTCTCTCTCTCTCTCT	TTCTCTCTCTCTCTCT	3: 53,752,626 (GRCm39)		probably null	Het
Gm5113	G	A	7: 29,878,178 (GRCm39)	V89I	probably benign	Het
Gtf3c2	A	C	5: 31,327,180 (GRCm39)	L382R	probably benign	Het
H3c2	T	C	13: 23,936,393 (GRCm39)	S11P	probably benign	Het
Hhip	T	C	8: 80,778,233 (GRCm39)	N99S	probably damaging	Het
Htr5b	T	C	1: 121,438,227 (GRCm39)	I335V	probably benign	Het
Ifi206	A	G	1: 173,308,923 (GRCm39)	S358P	unknown	Het
Loxhd1	T	A	18: 77,518,873 (GRCm39)	V1893D	probably damaging	Het
Mical2	A	G	7: 111,945,968 (GRCm39)	R11G	probably damaging	Het
Mrc1	T	C	2: 14,266,148 (GRCm39)		probably null	Het
Npr1	T	C	3: 90,363,560 (GRCm39)	N821S	probably benign	Het
Or4g16	A	G	2: 111,137,090 (GRCm39)	D180G	probably damaging	Het
Or52a24	A	G	7: 103,381,549 (GRCm39)	T139A	possibly damaging	Het
Or5p63	T	C	7: 107,811,670 (GRCm39)	D22G	probably benign	Het
Or5p70	T	G	7: 107,994,744 (GRCm39)	M139R	probably damaging	Het
Pi4ka	T	A	16: 17,143,852 (GRCm39)	D739V	probably damaging	Het
Pi4ka	A	G	16: 17,194,846 (GRCm39)	L184P	possibly damaging	Het
Ralgapb	G	A	2: 158,278,486 (GRCm39)	G5R	probably damaging	Het
Ric8b	T	C	10: 84,783,391 (GRCm39)	V83A	probably damaging	Het
Sdc2	C	A	15: 33,028,281 (GRCm39)	T133K	probably damaging	Het
Slc12a7	T	A	13: 73,947,088 (GRCm39)	V592D	probably damaging	Het
Sorcs1	G	T	19: 50,164,560 (GRCm39)	Y990*	probably null	Het
Spata13	G	T	14: 60,928,912 (GRCm39)	G157W	probably damaging	Het
Tada1	A	G	1: 166,217,541 (GRCm39)	N226S	probably benign	Het
Tenm3	A	G	8: 49,099,291 (GRCm39)		probably null	Het
Tll1	A	G	8: 64,524,315 (GRCm39)	V457A	probably benign	Het
Tmem232	T	C	17: 65,807,119 (GRCm39)	K25E	possibly damaging	Het
Tnrc18	T	C	5: 142,773,063 (GRCm39)	S406G	unknown	Het
Ush2a	A	G	1: 188,089,031 (GRCm39)	M329V	probably benign	Het
Vmn2r107	T	C	17: 20,577,141 (GRCm39)	S380P	probably damaging	Het
Vmn2r73	A	G	7: 85,519,563 (GRCm39)	M465T	probably benign	Het
Wwc2	A	G	8: 48,353,826 (GRCm39)	Y103H	possibly damaging	Het
Zfp217	T	C	2: 169,958,178 (GRCm39)	D463G	probably damaging	Het
Zfp345	T	C	2: 150,315,274 (GRCm39)	S88G	probably damaging	Het
Zfp975	A	C	7: 42,311,454 (GRCm39)	N386K	probably benign	Het

Other mutations in Ptprd

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00964:Ptprd	APN	4	75,916,793 (GRCm39)	nonsense	probably null
IGL01067:Ptprd	APN	4	75,977,922 (GRCm39)	missense	probably damaging	1.00
IGL01121:Ptprd	APN	4	75,872,438 (GRCm39)	splice site	probably benign
IGL01531:Ptprd	APN	4	76,003,757 (GRCm39)	missense	probably damaging	0.98
IGL01661:Ptprd	APN	4	75,872,320 (GRCm39)	missense	probably damaging	1.00
IGL01723:Ptprd	APN	4	76,161,910 (GRCm39)	missense	probably damaging	1.00
IGL01735:Ptprd	APN	4	76,055,057 (GRCm39)	splice site	probably null
IGL01810:Ptprd	APN	4	76,058,744 (GRCm39)	splice site	probably benign
IGL01834:Ptprd	APN	4	76,046,832 (GRCm39)	missense	probably damaging	1.00
IGL01835:Ptprd	APN	4	76,165,058 (GRCm39)	missense	probably benign	0.02
IGL01867:Ptprd	APN	4	76,161,884 (GRCm39)	missense	probably damaging	1.00
IGL02582:Ptprd	APN	4	75,865,361 (GRCm39)	missense	probably damaging	1.00
IGL02591:Ptprd	APN	4	75,900,287 (GRCm39)	missense	probably damaging	1.00
IGL02741:Ptprd	APN	4	76,051,521 (GRCm39)	missense	probably damaging	1.00
IGL02866:Ptprd	APN	4	75,968,674 (GRCm39)	missense	probably damaging	1.00
IGL02960:Ptprd	APN	4	76,047,105 (GRCm39)	missense	probably damaging	1.00
IGL03155:Ptprd	APN	4	75,984,456 (GRCm39)	missense	possibly damaging	0.95
IGL03230:Ptprd	APN	4	75,968,654 (GRCm39)	nonsense	probably null
IGL03343:Ptprd	APN	4	75,977,966 (GRCm39)	missense	probably damaging	1.00
unhurried	UTSW	4	76,018,870 (GRCm39)	nonsense	probably null
ANU22:Ptprd	UTSW	4	76,018,693 (GRCm39)	missense	probably damaging	0.99
F5493:Ptprd	UTSW	4	76,002,645 (GRCm39)	missense	probably damaging	1.00
P0033:Ptprd	UTSW	4	76,047,091 (GRCm39)	nonsense	probably null
R0044:Ptprd	UTSW	4	76,004,566 (GRCm39)	missense	probably benign	0.08
R0044:Ptprd	UTSW	4	76,004,566 (GRCm39)	missense	probably benign	0.08
R0076:Ptprd	UTSW	4	75,865,276 (GRCm39)	splice site	probably benign
R0137:Ptprd	UTSW	4	76,055,140 (GRCm39)	missense	probably benign	0.24
R0358:Ptprd	UTSW	4	75,863,226 (GRCm39)	missense	probably damaging	1.00
R0365:Ptprd	UTSW	4	76,055,083 (GRCm39)	missense	probably damaging	1.00
R0385:Ptprd	UTSW	4	76,046,902 (GRCm39)	missense	probably damaging	1.00
R0601:Ptprd	UTSW	4	76,018,711 (GRCm39)	missense	probably benign
R0646:Ptprd	UTSW	4	76,002,640 (GRCm39)	missense	probably damaging	0.99
R0667:Ptprd	UTSW	4	75,875,583 (GRCm39)	missense	probably damaging	1.00
R0707:Ptprd	UTSW	4	75,875,476 (GRCm39)	missense	probably damaging	1.00
R0734:Ptprd	UTSW	4	76,058,834 (GRCm39)	missense	probably damaging	1.00
R0827:Ptprd	UTSW	4	76,047,152 (GRCm39)	missense	probably damaging	0.98
R0932:Ptprd	UTSW	4	76,055,122 (GRCm39)	missense	probably damaging	1.00
R1069:Ptprd	UTSW	4	76,018,870 (GRCm39)	nonsense	probably null
R1069:Ptprd	UTSW	4	75,916,724 (GRCm39)	splice site	probably benign
R1086:Ptprd	UTSW	4	76,051,495 (GRCm39)	missense	probably damaging	1.00
R1439:Ptprd	UTSW	4	75,984,437 (GRCm39)	missense	probably damaging	1.00
R1440:Ptprd	UTSW	4	76,002,789 (GRCm39)	missense	probably damaging	0.98
R1688:Ptprd	UTSW	4	75,900,921 (GRCm39)	missense	probably damaging	1.00
R1858:Ptprd	UTSW	4	75,865,384 (GRCm39)	missense	probably damaging	1.00
R2001:Ptprd	UTSW	4	75,872,359 (GRCm39)	missense	probably damaging	1.00
R2020:Ptprd	UTSW	4	76,051,398 (GRCm39)	missense	probably damaging	1.00
R2023:Ptprd	UTSW	4	75,875,341 (GRCm39)	missense	probably damaging	1.00
R2413:Ptprd	UTSW	4	76,051,437 (GRCm39)	missense	probably damaging	1.00
R2510:Ptprd	UTSW	4	76,004,248 (GRCm39)	critical splice donor site	probably null
R2914:Ptprd	UTSW	4	75,865,338 (GRCm39)	missense	probably damaging	1.00
R2971:Ptprd	UTSW	4	76,025,561 (GRCm39)	missense	probably benign	0.10
R3051:Ptprd	UTSW	4	76,018,867 (GRCm39)	missense	probably damaging	1.00
R3433:Ptprd	UTSW	4	76,004,248 (GRCm39)	critical splice donor site	probably null
R3964:Ptprd	UTSW	4	75,978,073 (GRCm39)	splice site	probably benign
R4009:Ptprd	UTSW	4	75,874,634 (GRCm39)	missense	possibly damaging	0.94
R4394:Ptprd	UTSW	4	76,046,922 (GRCm39)	missense	probably damaging	1.00
R4420:Ptprd	UTSW	4	75,957,614 (GRCm39)	missense	possibly damaging	0.92
R4424:Ptprd	UTSW	4	76,021,200 (GRCm39)	missense	probably benign	0.22
R4575:Ptprd	UTSW	4	76,162,023 (GRCm39)	missense	possibly damaging	0.55
R4578:Ptprd	UTSW	4	76,162,023 (GRCm39)	missense	possibly damaging	0.55
R4715:Ptprd	UTSW	4	76,025,570 (GRCm39)	missense	probably benign	0.03
R4782:Ptprd	UTSW	4	76,009,769 (GRCm39)	missense	probably benign	0.01
R4785:Ptprd	UTSW	4	76,058,790 (GRCm39)	missense	probably benign	0.05
R4799:Ptprd	UTSW	4	76,009,769 (GRCm39)	missense	probably benign	0.01
R4944:Ptprd	UTSW	4	76,047,136 (GRCm39)	missense	probably damaging	1.00
R4950:Ptprd	UTSW	4	76,058,752 (GRCm39)	splice site	probably null
R4969:Ptprd	UTSW	4	76,051,542 (GRCm39)	missense	probably damaging	1.00
R5153:Ptprd	UTSW	4	75,930,339 (GRCm39)	missense	probably damaging	1.00
R5164:Ptprd	UTSW	4	76,018,995 (GRCm39)	splice site	probably null
R5287:Ptprd	UTSW	4	75,872,405 (GRCm39)	nonsense	probably null
R5305:Ptprd	UTSW	4	75,900,863 (GRCm39)	missense	probably damaging	1.00
R5362:Ptprd	UTSW	4	76,047,050 (GRCm39)	missense	probably damaging	1.00
R5403:Ptprd	UTSW	4	75,872,405 (GRCm39)	nonsense	probably null
R5531:Ptprd	UTSW	4	75,977,904 (GRCm39)	critical splice donor site	probably null
R5543:Ptprd	UTSW	4	75,977,990 (GRCm39)	missense	probably damaging	1.00
R5634:Ptprd	UTSW	4	75,990,255 (GRCm39)	missense	probably benign	0.01
R5719:Ptprd	UTSW	4	75,972,839 (GRCm39)	critical splice acceptor site	probably null
R5884:Ptprd	UTSW	4	75,900,927 (GRCm39)	missense	probably damaging	1.00
R6247:Ptprd	UTSW	4	75,984,528 (GRCm39)	missense	probably benign	0.06
R6250:Ptprd	UTSW	4	76,047,232 (GRCm39)	missense	probably damaging	1.00
R6335:Ptprd	UTSW	4	75,872,420 (GRCm39)	missense	probably damaging	1.00
R6352:Ptprd	UTSW	4	76,009,789 (GRCm39)	splice site	probably null
R6533:Ptprd	UTSW	4	76,046,765 (GRCm39)	missense	probably damaging	1.00
R6756:Ptprd	UTSW	4	75,873,536 (GRCm39)	missense	probably damaging	1.00
R7131:Ptprd	UTSW	4	75,984,577 (GRCm39)	missense	probably damaging	1.00
R7170:Ptprd	UTSW	4	75,990,199 (GRCm39)	missense	probably benign	0.06
R7233:Ptprd	UTSW	4	75,978,020 (GRCm39)	missense	probably benign	0.00
R7246:Ptprd	UTSW	4	76,046,913 (GRCm39)	missense	probably damaging	1.00
R7413:Ptprd	UTSW	4	76,165,076 (GRCm39)	missense	probably benign	0.00
R7428:Ptprd	UTSW	4	76,004,705 (GRCm39)	missense	probably benign	0.03
R7442:Ptprd	UTSW	4	75,978,058 (GRCm39)	nonsense	probably null
R7491:Ptprd	UTSW	4	76,051,392 (GRCm39)	missense	probably benign	0.23
R7526:Ptprd	UTSW	4	75,984,564 (GRCm39)	missense	probably benign	0.00
R7609:Ptprd	UTSW	4	75,990,240 (GRCm39)	missense	probably benign	0.03
R7612:Ptprd	UTSW	4	76,004,696 (GRCm39)	missense	probably benign	0.45
R7659:Ptprd	UTSW	4	76,047,153 (GRCm39)	missense	probably benign	0.03
R7743:Ptprd	UTSW	4	76,004,326 (GRCm39)	missense	probably damaging	1.00
R7748:Ptprd	UTSW	4	76,017,741 (GRCm39)	missense	probably null	0.39
R7788:Ptprd	UTSW	4	75,916,841 (GRCm39)	missense	probably damaging	1.00
R7836:Ptprd	UTSW	4	75,900,881 (GRCm39)	missense	probably damaging	0.99
R7937:Ptprd	UTSW	4	76,013,772 (GRCm39)	missense	probably benign	0.00
R8000:Ptprd	UTSW	4	75,984,479 (GRCm39)	missense	possibly damaging	0.95
R8018:Ptprd	UTSW	4	76,003,757 (GRCm39)	missense	probably damaging	0.98
R8072:Ptprd	UTSW	4	76,004,273 (GRCm39)	missense	probably benign	0.01
R8119:Ptprd	UTSW	4	76,047,263 (GRCm39)	missense	probably benign	0.00
R8350:Ptprd	UTSW	4	75,868,898 (GRCm39)	missense	probably damaging	1.00
R8387:Ptprd	UTSW	4	75,873,526 (GRCm39)	missense	probably damaging	1.00
R8458:Ptprd	UTSW	4	75,984,496 (GRCm39)	missense	probably benign	0.00
R8529:Ptprd	UTSW	4	76,047,262 (GRCm39)	missense	probably damaging	1.00
R8699:Ptprd	UTSW	4	75,959,629 (GRCm39)	missense	probably benign
R8924:Ptprd	UTSW	4	75,916,736 (GRCm39)	critical splice donor site	probably null
R8984:Ptprd	UTSW	4	75,863,251 (GRCm39)	missense	probably damaging	1.00
R9024:Ptprd	UTSW	4	75,874,567 (GRCm39)	missense	probably damaging	1.00
R9204:Ptprd	UTSW	4	75,872,315 (GRCm39)	missense	possibly damaging	0.46
R9206:Ptprd	UTSW	4	75,872,315 (GRCm39)	missense	possibly damaging	0.46
R9259:Ptprd	UTSW	4	75,990,200 (GRCm39)	missense	probably damaging	0.99
R9311:Ptprd	UTSW	4	76,051,320 (GRCm39)	missense	probably benign	0.25
R9417:Ptprd	UTSW	4	75,865,335 (GRCm39)	missense	probably damaging	0.99
R9427:Ptprd	UTSW	4	76,051,440 (GRCm39)	missense	probably benign	0.01
R9579:Ptprd	UTSW	4	75,872,315 (GRCm39)	missense	possibly damaging	0.46
R9580:Ptprd	UTSW	4	75,872,315 (GRCm39)	missense	possibly damaging	0.46
R9701:Ptprd	UTSW	4	75,916,896 (GRCm39)	missense	probably damaging	1.00
RF016:Ptprd	UTSW	4	76,046,892 (GRCm39)	missense	probably benign	0.01
RF023:Ptprd	UTSW	4	76,046,802 (GRCm39)	missense	probably damaging	0.98
Z1176:Ptprd	UTSW	4	76,051,451 (GRCm39)	missense	probably benign	0.00

Predicted Primers

PCR Primer
(F):5'- TTGTCACAAGGCTAGTAGGAAG -3'
(R):5'- GCTGAAGTTTCTGAGCGGAG -3'

Sequencing Primer
(F):5'- GGAGCAGTTAGACACACAAGC -3'
(R):5'- GCAGTCGCTGTGGCTCC -3'

Posted On

2018-08-29