Incidental Mutation 'IGL00474:Vmn1r120'
| ID |
5316 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r120
|
| Ensembl Gene |
ENSMUSG00000093986 |
| Gene Name |
vomeronasal 1 receptor 120 |
| Synonyms |
Gm5730 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.052)
|
| Stock # |
IGL00474
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
20786792-20787709 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 20786935 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 259
(I259F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000100837
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000105202]
|
| AlphaFold |
K7N6J6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000105202
AA Change: I259F
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000100837
Gene: ENSMUSG00000093986
AA Change: I259F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
8 |
297 |
2.3e-15 |
PFAM |
|
Pfam:7tm_1
|
31 |
286 |
3.6e-6 |
PFAM |
|
Pfam:V1R
|
41 |
296 |
6.4e-13 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 10 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam12 |
T |
C |
7: 133,511,610 (GRCm39) |
K730R |
possibly damaging |
Het |
| Adgrf4 |
T |
C |
17: 42,986,650 (GRCm39) |
I36M |
probably damaging |
Het |
| Atp2a1 |
A |
T |
7: 126,049,466 (GRCm39) |
C525* |
probably null |
Het |
| Col11a1 |
A |
C |
3: 113,860,182 (GRCm39) |
M203L |
unknown |
Het |
| Duox2 |
T |
A |
2: 122,114,056 (GRCm39) |
M1159L |
probably benign |
Het |
| Harbi1 |
T |
G |
2: 91,542,971 (GRCm39) |
V144G |
probably damaging |
Het |
| Kcp |
A |
G |
6: 29,482,656 (GRCm39) |
V1471A |
probably benign |
Het |
| Lrig1 |
G |
T |
6: 94,588,385 (GRCm39) |
T588K |
probably damaging |
Het |
| Lyst |
A |
G |
13: 13,818,121 (GRCm39) |
I1264V |
possibly damaging |
Het |
| Slc4a11 |
A |
T |
2: 130,530,058 (GRCm39) |
M240K |
probably benign |
Het |
|
| Other mutations in Vmn1r120 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02533:Vmn1r120
|
APN |
7 |
20,787,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03261:Vmn1r120
|
APN |
7 |
20,787,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0539:Vmn1r120
|
UTSW |
7 |
20,787,397 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0973:Vmn1r120
|
UTSW |
7 |
20,786,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1831:Vmn1r120
|
UTSW |
7 |
20,787,556 (GRCm39) |
missense |
probably benign |
|
|
R2034:Vmn1r120
|
UTSW |
7 |
20,786,883 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R2149:Vmn1r120
|
UTSW |
7 |
20,786,889 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3437:Vmn1r120
|
UTSW |
7 |
20,787,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5449:Vmn1r120
|
UTSW |
7 |
20,787,074 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5548:Vmn1r120
|
UTSW |
7 |
20,787,482 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5730:Vmn1r120
|
UTSW |
7 |
20,786,934 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6305:Vmn1r120
|
UTSW |
7 |
20,787,531 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7348:Vmn1r120
|
UTSW |
7 |
20,787,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8435:Vmn1r120
|
UTSW |
7 |
20,787,557 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8486:Vmn1r120
|
UTSW |
7 |
20,787,027 (GRCm39) |
missense |
probably benign |
|
|
R9613:Vmn1r120
|
UTSW |
7 |
20,787,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
| Posted On |
2012-04-20 |
Incidental Mutation