Incidental Mutation 'IGL01018:Vmn2r125'
ID53543
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r125
Ensembl Gene ENSMUSG00000096042
Gene Namevomeronasal 2, receptor 125
SynonymsGm20782
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.072) question?
Stock #IGL01018
Quality Score
Status
Chromosome4
Chromosomal Location156349921-156354578 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to A at 156350899 bp
ZygosityHeterozygous
Amino Acid Change Glutamine to Lysine at position 191 (Q191K)
Ref Sequence ENSEMBL: ENSMUSP00000094556 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000096794]
Predicted Effect probably benign
Transcript: ENSMUST00000096794
AA Change: Q191K

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000094556
Gene: ENSMUSG00000096042
AA Change: Q191K

DomainStartEndE-ValueType
Pfam:ANF_receptor 9 355 7e-32 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4931408C20Rik T C 1: 26,682,910 E1063G probably damaging Het
5530400C23Rik G T 6: 133,294,497 R168I probably benign Het
5530400C23Rik A T 6: 133,294,498 R168S probably benign Het
9230019H11Rik G A 10: 3,125,031 noncoding transcript Het
9230019H11Rik C T 10: 3,125,193 noncoding transcript Het
9230019H11Rik A G 10: 3,120,231 noncoding transcript Het
9230019H11Rik A G 10: 3,120,209 noncoding transcript Het
Armt1 T A 10: 4,450,732 S160T probably benign Het
Armt1 C T 10: 4,454,237 probably benign Het
Ccdc170 T C 10: 4,512,788 W35R probably benign Het
Ccdc170 G T 10: 4,514,155 A99S probably benign Het
Ccdc170 T C 10: 4,514,114 V31A probably benign Het
Glp2r C A 11: 67,709,644 V460F probably benign Het
Gm21411 C T 4: 146,892,610 S69N possibly damaging Het
Gm21411 T C 4: 146,892,577 Q80R probably benign Het
Gm21671 G T 5: 25,950,723 H208N probably benign Het
Gm21738 G A 14: 19,418,856 P24L probably benign Het
H2-M10.6 C T 17: 36,812,220 A15V probably benign Het
H60c T C 10: 3,259,766 M174V probably benign Het
H60c A C 10: 3,260,343 F69V probably benign Het
Ipcef1 C T 10: 6,919,968 R144Q probably damaging Het
Ipcef1 G A 10: 6,890,551 A382V probably benign Het
Mapk8ip3 T G 17: 24,899,719 probably benign Het
Mthfd1l T C 10: 3,978,708 V100A probably benign Het
Mthfd1l T C 10: 4,007,800 V279A probably benign Het
Mthfd1l T C 10: 4,032,345 probably benign Het
Mtrf1l A G 10: 5,814,180 probably benign Het
Myo18b T C 5: 112,809,747 E1450G probably damaging Het
Obscn C T 11: 59,128,069 V973M probably damaging Het
Olfr414 G A 1: 174,431,342 V305I probably benign Het
Oprm1 T C 10: 7,037,170 probably benign Het
Pou5f2 A G 13: 78,025,938 probably benign Het
Ralgapa2 G A 2: 146,410,193 H891Y probably benign Het
Ralgapa2 T G 2: 146,410,192 H806P probably benign Het
Rmnd1 A T 10: 4,427,290 S130T probably benign Het
Rmnd1 A G 10: 4,427,392 W96R probably benign Het
Trappc12 A C 12: 28,691,854 probably benign Het
Vip A G 10: 5,642,480 D40G probably benign Het
Vmn2r40 G A 7: 8,908,176 S706F probably damaging Het
Vmn2r-ps159 G A 4: 156,334,605 noncoding transcript Het
Vmn2r-ps159 A T 4: 156,338,146 noncoding transcript Het
Vmn2r-ps159 C A 4: 156,338,435 noncoding transcript Het
Vmn2r-ps159 T C 4: 156,334,263 noncoding transcript Het
Vmn2r-ps159 T C 4: 156,335,590 noncoding transcript Het
Zfp14 T A 7: 30,038,101 R486S probably damaging Het
Other mutations in Vmn2r125
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00990:Vmn2r125 APN 4 156351226 missense probably benign
IGL00990:Vmn2r125 APN 4 156351383 missense probably benign 0.00
IGL00990:Vmn2r125 APN 4 156350966 missense probably benign 0.01
IGL00990:Vmn2r125 APN 4 156350900 missense probably benign 0.35
IGL00990:Vmn2r125 APN 4 156350899 missense probably benign
IGL00990:Vmn2r125 APN 4 156351038 missense probably benign 0.06
IGL00990:Vmn2r125 APN 4 156351037 missense probably benign 0.16
IGL01018:Vmn2r125 APN 4 156351226 missense probably benign
IGL01018:Vmn2r125 APN 4 156351038 missense probably benign 0.06
IGL01018:Vmn2r125 APN 4 156351037 missense probably benign 0.16
IGL01018:Vmn2r125 APN 4 156350900 missense probably benign 0.35
IGL01018:Vmn2r125 APN 4 156350845 missense probably damaging 1.00
IGL01018:Vmn2r125 APN 4 156350612 splice site probably benign
IGL02644:Vmn2r125 APN 4 156350999 missense probably benign 0.01
IGL03144:Vmn2r125 APN 4 156350019 missense possibly damaging 0.76
FR4342:Vmn2r125 UTSW 4 156350965 missense probably benign 0.01
R0408:Vmn2r125 UTSW 4 156350858 missense probably damaging 0.99
R0785:Vmn2r125 UTSW 4 156351101 missense probably benign
R1185:Vmn2r125 UTSW 4 156351101 missense probably benign
R1530:Vmn2r125 UTSW 4 156351152 missense probably damaging 1.00
R1698:Vmn2r125 UTSW 4 156351038 missense probably benign 0.06
R1780:Vmn2r125 UTSW 4 156351373 missense probably damaging 1.00
R1977:Vmn2r125 UTSW 4 156354591 unclassified probably null
R2917:Vmn2r125 UTSW 4 156351269 missense probably benign 0.01
R3428:Vmn2r125 UTSW 4 156350141 missense probably benign 0.34
R3712:Vmn2r125 UTSW 4 156350124 nonsense probably null
R4274:Vmn2r125 UTSW 4 156350087 missense probably benign 0.00
R4575:Vmn2r125 UTSW 4 156349977 missense probably null 0.30
R4707:Vmn2r125 UTSW 4 156349981 missense probably damaging 1.00
R5229:Vmn2r125 UTSW 4 156351038 missense probably benign 0.06
R5504:Vmn2r125 UTSW 4 156351161 missense possibly damaging 0.81
R5587:Vmn2r125 UTSW 4 156350138 missense probably damaging 1.00
R5987:Vmn2r125 UTSW 4 156349997 missense probably damaging 1.00
R6037:Vmn2r125 UTSW 4 156351101 missense probably benign
R6183:Vmn2r125 UTSW 4 156350069 missense probably damaging 0.97
R6456:Vmn2r125 UTSW 4 156351062 missense probably benign 0.41
Posted On2013-06-28