Incidental Mutation 'R6861:Idh2'
| ID |
535523 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Idh2
|
| Ensembl Gene |
ENSMUSG00000030541 |
| Gene Name |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| Synonyms |
Idh-2, IDPm |
| MMRRC Submission |
044962-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6861 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
79744594-79765140 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 79747966 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Serine
at position 245
(P245S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000103007
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000107384]
[ENSMUST00000125542]
[ENSMUST00000134328]
[ENSMUST00000164056]
[ENSMUST00000206714]
|
| AlphaFold |
P54071 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107384
AA Change: P245S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000103007
Gene: ENSMUSG00000030541
AA Change: P245S
| Domain | Start | End | E-Value | Type |
|---|
|
Iso_dh
|
49 |
441 |
5.32e-135 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125542
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000134328
AA Change: A281V
|
| SMART Domains |
Protein: ENSMUSP00000118184
Gene: ENSMUSG00000030541
AA Change: A281V
| Domain | Start | End | E-Value | Type |
|---|
|
Iso_dh
|
49 |
284 |
1.59e-8 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164056
|
| SMART Domains |
Protein: ENSMUSP00000132361
Gene: ENSMUSG00000048897
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
88 |
N/A |
INTRINSIC |
|
low complexity region
|
106 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
181 |
N/A |
INTRINSIC |
|
low complexity region
|
187 |
201 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
297 |
319 |
2.71e-2 |
SMART |
|
ZnF_C2H2
|
325 |
347 |
1.92e-2 |
SMART |
|
ZnF_C2H2
|
353 |
375 |
2.71e-2 |
SMART |
|
ZnF_C2H2
|
381 |
403 |
1.18e-2 |
SMART |
|
ZnF_C2H2
|
409 |
431 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
437 |
459 |
4.87e-4 |
SMART |
|
ZnF_C2H2
|
465 |
487 |
3.83e-2 |
SMART |
|
ZnF_C2H2
|
493 |
515 |
2.12e-4 |
SMART |
|
ZnF_C2H2
|
521 |
543 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
549 |
571 |
1.58e-3 |
SMART |
|
ZnF_C2H2
|
577 |
600 |
3.69e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206714
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit suppression of tumorigenesis from B16F10 melanoma cells. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl4 |
G |
A |
3: 95,588,194 (GRCm39) |
R598C |
probably damaging |
Het |
| Adra2a |
T |
C |
19: 54,034,818 (GRCm39) |
L58P |
probably damaging |
Het |
| Ajm1 |
C |
CTCTA |
2: 25,469,733 (GRCm39) |
|
probably null |
Het |
| Alox5ap |
A |
G |
5: 149,201,927 (GRCm39) |
D2G |
probably damaging |
Het |
| Arid1b |
G |
A |
17: 5,377,961 (GRCm39) |
V1238M |
possibly damaging |
Het |
| Bank1 |
A |
G |
3: 135,960,764 (GRCm39) |
V31A |
probably benign |
Het |
| Bptf |
G |
A |
11: 106,953,391 (GRCm39) |
T2117M |
probably damaging |
Het |
| Cadps |
G |
A |
14: 12,522,401 (GRCm38) |
R588* |
probably null |
Het |
| Cavin4 |
A |
G |
4: 48,672,214 (GRCm39) |
I220V |
probably benign |
Het |
| Cep192 |
G |
A |
18: 67,974,699 (GRCm39) |
M1267I |
probably benign |
Het |
| Cers5 |
G |
A |
15: 99,670,244 (GRCm39) |
|
probably benign |
Het |
| Cfap65 |
A |
T |
1: 74,964,274 (GRCm39) |
I558N |
probably damaging |
Het |
| Cfh |
A |
T |
1: 140,028,621 (GRCm39) |
S1025T |
probably benign |
Het |
| Cftr |
A |
G |
6: 18,268,107 (GRCm39) |
I689V |
probably benign |
Het |
| Cgrrf1 |
T |
C |
14: 47,069,785 (GRCm39) |
I18T |
probably damaging |
Het |
| CK137956 |
A |
G |
4: 127,864,519 (GRCm39) |
S37P |
probably damaging |
Het |
| Clca4a |
T |
C |
3: 144,676,416 (GRCm39) |
D88G |
probably benign |
Het |
| Col11a1 |
G |
A |
3: 113,961,141 (GRCm39) |
G1166D |
probably damaging |
Het |
| Col24a1 |
G |
A |
3: 145,166,589 (GRCm39) |
G1075S |
probably damaging |
Het |
| Crispld2 |
C |
T |
8: 120,752,852 (GRCm39) |
T299M |
probably damaging |
Het |
| Cyb561a3 |
T |
A |
19: 10,562,701 (GRCm39) |
Y114N |
probably damaging |
Het |
| Cyp3a57 |
T |
A |
5: 145,307,773 (GRCm39) |
W147R |
possibly damaging |
Het |
| Dnah2 |
C |
A |
11: 69,346,789 (GRCm39) |
R2599L |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,373,207 (GRCm39) |
S525T |
probably benign |
Het |
| Drc7 |
T |
G |
8: 95,789,025 (GRCm39) |
|
probably null |
Het |
| Efhd2 |
G |
T |
4: 141,587,192 (GRCm39) |
|
probably null |
Het |
| Epb41l1 |
A |
T |
2: 156,367,142 (GRCm39) |
E658D |
probably benign |
Het |
| Evi5 |
C |
T |
5: 107,896,184 (GRCm39) |
S753N |
probably benign |
Het |
| Exoc3 |
A |
T |
13: 74,337,319 (GRCm39) |
D427E |
probably benign |
Het |
| Fbxw9 |
A |
G |
8: 85,792,740 (GRCm39) |
D363G |
probably damaging |
Het |
| Fcer2a |
T |
C |
8: 3,732,910 (GRCm39) |
Y277C |
probably damaging |
Het |
| Fstl5 |
A |
T |
3: 76,229,523 (GRCm39) |
Y108F |
probably damaging |
Het |
| Gcn1 |
A |
G |
5: 115,749,108 (GRCm39) |
D1880G |
probably benign |
Het |
| Gm4924 |
T |
A |
10: 82,214,948 (GRCm39) |
Y915* |
probably null |
Het |
| Gpr139 |
T |
A |
7: 118,743,875 (GRCm39) |
I237F |
probably benign |
Het |
| Hao2 |
A |
G |
3: 98,784,498 (GRCm39) |
L289S |
probably damaging |
Het |
| Hexim1 |
A |
G |
11: 103,007,793 (GRCm39) |
S16G |
probably benign |
Het |
| Hmgcs1 |
T |
A |
13: 120,161,535 (GRCm39) |
M109K |
probably damaging |
Het |
| Hs3st4 |
T |
A |
7: 123,996,052 (GRCm39) |
N239K |
possibly damaging |
Het |
| Hsd3b5 |
T |
A |
3: 98,529,328 (GRCm39) |
N101Y |
probably damaging |
Het |
| Irx3 |
A |
G |
8: 92,525,530 (GRCm39) |
|
probably benign |
Het |
| Lilra5 |
A |
T |
7: 4,244,931 (GRCm39) |
D234V |
probably benign |
Het |
| Lrfn5 |
G |
A |
12: 61,886,476 (GRCm39) |
S88N |
probably damaging |
Het |
| Lrp2 |
A |
T |
2: 69,343,721 (GRCm39) |
S879R |
possibly damaging |
Het |
| Lsm11 |
A |
G |
11: 45,824,781 (GRCm39) |
S249P |
probably benign |
Het |
| Ltbp1 |
C |
T |
17: 75,534,187 (GRCm39) |
A543V |
possibly damaging |
Het |
| Mbd1 |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
18: 74,406,645 (GRCm39) |
|
|
Het |
| Mier2 |
C |
T |
10: 79,376,990 (GRCm39) |
|
probably benign |
Het |
| Mup6 |
G |
C |
4: 60,004,093 (GRCm39) |
G70A |
probably benign |
Het |
| Neb |
A |
G |
2: 52,085,732 (GRCm39) |
L5258P |
probably damaging |
Het |
| Nlrc5 |
G |
A |
8: 95,247,857 (GRCm39) |
|
probably benign |
Het |
| Nr6a1 |
A |
T |
2: 38,630,597 (GRCm39) |
F207I |
possibly damaging |
Het |
| Or2y1 |
A |
T |
11: 49,385,632 (GRCm39) |
T91S |
probably benign |
Het |
| Or5k17 |
A |
T |
16: 58,746,867 (GRCm39) |
D22E |
probably benign |
Het |
| Or8b43 |
T |
C |
9: 38,360,731 (GRCm39) |
C188R |
probably damaging |
Het |
| Osbp2 |
A |
G |
11: 3,665,191 (GRCm39) |
V51A |
possibly damaging |
Het |
| Papln |
G |
T |
12: 83,821,723 (GRCm39) |
C317F |
probably damaging |
Het |
| Pdcd7 |
T |
C |
9: 65,265,904 (GRCm39) |
S454P |
probably damaging |
Het |
| Pde4a |
C |
T |
9: 21,116,597 (GRCm39) |
T473I |
probably damaging |
Het |
| Peg10 |
CC |
CCCCATCAGGC |
6: 4,756,350 (GRCm39) |
|
probably benign |
Het |
| Peg10 |
C |
CCCATCAGGA |
6: 4,756,351 (GRCm39) |
|
probably benign |
Het |
| Peg3 |
G |
T |
7: 6,714,385 (GRCm39) |
S279* |
probably null |
Het |
| Rbl1 |
A |
G |
2: 156,994,887 (GRCm39) |
Y929H |
probably damaging |
Het |
| Rsf1 |
G |
GACGGCGGCA |
7: 97,229,116 (GRCm39) |
|
probably benign |
Het |
| Sall3 |
C |
A |
18: 81,017,590 (GRCm39) |
E113* |
probably null |
Het |
| Scn5a |
A |
C |
9: 119,359,089 (GRCm39) |
F653V |
probably damaging |
Het |
| Selenok |
T |
A |
14: 29,692,005 (GRCm39) |
N14K |
possibly damaging |
Het |
| Slc22a20 |
T |
C |
19: 6,021,838 (GRCm39) |
T426A |
probably benign |
Het |
| Slc4a2 |
T |
A |
5: 24,640,007 (GRCm39) |
S563T |
probably damaging |
Het |
| Sspo |
T |
A |
6: 48,464,889 (GRCm39) |
S3798T |
probably benign |
Het |
| Stag3 |
G |
T |
5: 138,302,969 (GRCm39) |
R63L |
possibly damaging |
Het |
| Stard9 |
A |
T |
2: 120,535,667 (GRCm39) |
M3975L |
probably benign |
Het |
| Syne2 |
C |
A |
12: 75,956,040 (GRCm39) |
T582K |
probably damaging |
Het |
| Synj1 |
G |
A |
16: 90,760,768 (GRCm39) |
Q748* |
probably null |
Het |
| Tas2r109 |
T |
C |
6: 132,957,048 (GRCm39) |
D294G |
probably benign |
Het |
| Tbl1xr1 |
C |
T |
3: 22,245,603 (GRCm39) |
T203M |
possibly damaging |
Het |
| Tbl1xr1 |
T |
A |
3: 22,245,703 (GRCm39) |
|
probably null |
Het |
| Tcf7l2 |
A |
G |
19: 55,730,955 (GRCm39) |
D19G |
probably damaging |
Het |
| Tecta |
A |
G |
9: 42,248,633 (GRCm39) |
V1923A |
possibly damaging |
Het |
| Tg |
T |
A |
15: 66,560,740 (GRCm39) |
M1034K |
probably benign |
Het |
| Ttf2 |
T |
C |
3: 100,876,941 (GRCm39) |
E8G |
possibly damaging |
Het |
| Vps13b |
T |
A |
15: 35,576,541 (GRCm39) |
V983E |
probably damaging |
Het |
| Vps35l |
A |
G |
7: 118,342,898 (GRCm39) |
H32R |
probably damaging |
Het |
| Vwa2 |
T |
C |
19: 56,890,025 (GRCm39) |
V210A |
probably benign |
Het |
| Xkr6 |
T |
A |
14: 64,057,093 (GRCm39) |
Y335N |
probably benign |
Het |
| Zfp97 |
A |
G |
17: 17,365,437 (GRCm39) |
H312R |
probably damaging |
Het |
|
| Other mutations in Idh2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01529:Idh2
|
APN |
7 |
79,747,693 (GRCm39) |
missense |
probably benign |
|
|
IGL02281:Idh2
|
APN |
7 |
79,745,550 (GRCm39) |
splice site |
probably null |
|
|
IGL02874:Idh2
|
APN |
7 |
79,747,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02892:Idh2
|
APN |
7 |
79,745,418 (GRCm39) |
missense |
probably benign |
|
|
IGL02937:Idh2
|
APN |
7 |
79,748,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02989:Idh2
|
APN |
7 |
79,748,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Idh2
|
UTSW |
7 |
79,747,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Idh2
|
UTSW |
7 |
79,747,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0090:Idh2
|
UTSW |
7 |
79,747,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0322:Idh2
|
UTSW |
7 |
79,748,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0384:Idh2
|
UTSW |
7 |
79,748,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0385:Idh2
|
UTSW |
7 |
79,748,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0386:Idh2
|
UTSW |
7 |
79,748,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0387:Idh2
|
UTSW |
7 |
79,748,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0494:Idh2
|
UTSW |
7 |
79,748,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1603:Idh2
|
UTSW |
7 |
79,748,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1681:Idh2
|
UTSW |
7 |
79,748,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1711:Idh2
|
UTSW |
7 |
79,748,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1844:Idh2
|
UTSW |
7 |
79,748,625 (GRCm39) |
missense |
probably benign |
0.31 |
|
R3700:Idh2
|
UTSW |
7 |
79,748,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4941:Idh2
|
UTSW |
7 |
79,745,847 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5234:Idh2
|
UTSW |
7 |
79,745,853 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5387:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R5582:Idh2
|
UTSW |
7 |
79,748,087 (GRCm39) |
frame shift |
probably null |
|
|
R5655:Idh2
|
UTSW |
7 |
79,747,996 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6191:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R6261:Idh2
|
UTSW |
7 |
79,748,077 (GRCm39) |
intron |
probably benign |
|
|
R6311:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R6351:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R6413:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R6561:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R6709:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R6772:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R6781:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R6848:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R6899:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R7063:Idh2
|
UTSW |
7 |
79,745,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7076:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R7081:Idh2
|
UTSW |
7 |
79,748,077 (GRCm39) |
intron |
probably benign |
|
|
R7090:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R7254:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
frame shift |
probably null |
|
|
R7298:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R7401:Idh2
|
UTSW |
7 |
79,748,077 (GRCm39) |
intron |
probably benign |
|
|
R7560:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
frame shift |
probably null |
|
|
R7561:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R7694:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R7816:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R7884:Idh2
|
UTSW |
7 |
79,748,077 (GRCm39) |
intron |
probably benign |
|
|
R7919:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R7961:Idh2
|
UTSW |
7 |
79,748,001 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8009:Idh2
|
UTSW |
7 |
79,748,001 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8036:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8162:Idh2
|
UTSW |
7 |
79,748,077 (GRCm39) |
intron |
probably benign |
|
|
R8321:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8451:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8488:Idh2
|
UTSW |
7 |
79,748,077 (GRCm39) |
intron |
probably benign |
|
|
R8501:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8671:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8673:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8707:Idh2
|
UTSW |
7 |
79,748,077 (GRCm39) |
intron |
probably benign |
|
|
R8725:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
frame shift |
probably null |
|
|
R8863:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8872:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8892:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8915:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8935:Idh2
|
UTSW |
7 |
79,764,946 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8951:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8954:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R8985:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R9101:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R9111:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R9138:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
frame shift |
probably null |
|
|
R9138:Idh2
|
UTSW |
7 |
79,748,077 (GRCm39) |
intron |
probably benign |
|
|
R9140:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R9555:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R9580:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R9614:Idh2
|
UTSW |
7 |
79,747,925 (GRCm39) |
nonsense |
probably null |
|
|
R9619:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R9697:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R9756:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
R9790:Idh2
|
UTSW |
7 |
79,748,079 (GRCm39) |
intron |
probably benign |
|
|
RF030:Idh2
|
UTSW |
7 |
79,748,077 (GRCm39) |
intron |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGAACCAAGCGCACACTAGG -3'
(R):5'- TCTGTGCTCCCAGAAGTCTG -3'
Sequencing Primer
(F):5'- TAGGAAAGCAACCTCCCCAGG -3'
(R):5'- AGATTGGCCAAGCATTCCGTG -3'
|
| Posted On |
2018-09-12 |
Incidental Mutation