Incidental Mutation 'R6861:Synj1'
| ID |
535561 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Synj1
|
| Ensembl Gene |
ENSMUSG00000022973 |
| Gene Name |
synaptojanin 1 |
| Synonyms |
A930006D20Rik |
| MMRRC Submission |
044962-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R6861 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
90732980-90808196 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
G to A
at 90760768 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Stop codon
at position 748
(Q748*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128997
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000121759]
[ENSMUST00000130813]
[ENSMUST00000170853]
[ENSMUST00000231472]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000118390
AA Change: Q762*
|
| SMART Domains |
Protein: ENSMUSP00000113518
Gene: ENSMUSG00000022973
AA Change: Q762*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
1 |
15 |
N/A |
INTRINSIC |
|
Pfam:Syja_N
|
75 |
356 |
3.1e-71 |
PFAM |
|
IPPc
|
546 |
889 |
6.37e-177 |
SMART |
|
DUF1866
|
882 |
1024 |
1.24e-80 |
SMART |
|
low complexity region
|
1040 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1117 |
1151 |
N/A |
INTRINSIC |
|
low complexity region
|
1155 |
1166 |
N/A |
INTRINSIC |
|
low complexity region
|
1189 |
1208 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1322 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000121759
AA Change: Q788*
|
| SMART Domains |
Protein: ENSMUSP00000113308
Gene: ENSMUSG00000022973
AA Change: Q788*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
9 |
40 |
N/A |
INTRINSIC |
|
Pfam:Syja_N
|
100 |
381 |
4.2e-71 |
PFAM |
|
IPPc
|
571 |
914 |
6.37e-177 |
SMART |
|
DUF1866
|
907 |
1049 |
1.24e-80 |
SMART |
|
low complexity region
|
1065 |
1094 |
N/A |
INTRINSIC |
|
low complexity region
|
1142 |
1176 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1214 |
1233 |
N/A |
INTRINSIC |
|
low complexity region
|
1314 |
1343 |
N/A |
INTRINSIC |
|
Blast:IPPc
|
1344 |
1428 |
1e-17 |
BLAST |
|
low complexity region
|
1564 |
1596 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000130813
|
| SMART Domains |
Protein: ENSMUSP00000119712
Gene: ENSMUSG00000022973
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Syja_N
|
59 |
346 |
1.4e-86 |
PFAM |
|
low complexity region
|
441 |
459 |
N/A |
INTRINSIC |
|
IPPc
|
526 |
693 |
1.8e-9 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000170853
AA Change: Q748*
|
| SMART Domains |
Protein: ENSMUSP00000128997
Gene: ENSMUSG00000022973
AA Change: Q748*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Syja_N
|
59 |
346 |
1.7e-85 |
PFAM |
|
IPPc
|
531 |
874 |
6.37e-177 |
SMART |
|
DUF1866
|
867 |
1009 |
1.24e-80 |
SMART |
|
low complexity region
|
1025 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1136 |
N/A |
INTRINSIC |
|
low complexity region
|
1140 |
1151 |
N/A |
INTRINSIC |
|
low complexity region
|
1174 |
1193 |
N/A |
INTRINSIC |
|
low complexity region
|
1274 |
1307 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000231472
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
PHENOTYPE: Homozygotes for a targeted null mutation exhibit neurological defects associated with impaired phosphoinositide metabolism and accumulation of clathrin-coated vesicles at nerve endings. Mutants show impaired suckling and most die within 24 hours of birth. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl4 |
G |
A |
3: 95,588,194 (GRCm39) |
R598C |
probably damaging |
Het |
| Adra2a |
T |
C |
19: 54,034,818 (GRCm39) |
L58P |
probably damaging |
Het |
| Ajm1 |
C |
CTCTA |
2: 25,469,733 (GRCm39) |
|
probably null |
Het |
| Alox5ap |
A |
G |
5: 149,201,927 (GRCm39) |
D2G |
probably damaging |
Het |
| Arid1b |
G |
A |
17: 5,377,961 (GRCm39) |
V1238M |
possibly damaging |
Het |
| Bank1 |
A |
G |
3: 135,960,764 (GRCm39) |
V31A |
probably benign |
Het |
| Bptf |
G |
A |
11: 106,953,391 (GRCm39) |
T2117M |
probably damaging |
Het |
| Cadps |
G |
A |
14: 12,522,401 (GRCm38) |
R588* |
probably null |
Het |
| Cavin4 |
A |
G |
4: 48,672,214 (GRCm39) |
I220V |
probably benign |
Het |
| Cep192 |
G |
A |
18: 67,974,699 (GRCm39) |
M1267I |
probably benign |
Het |
| Cers5 |
G |
A |
15: 99,670,244 (GRCm39) |
|
probably benign |
Het |
| Cfap65 |
A |
T |
1: 74,964,274 (GRCm39) |
I558N |
probably damaging |
Het |
| Cfh |
A |
T |
1: 140,028,621 (GRCm39) |
S1025T |
probably benign |
Het |
| Cftr |
A |
G |
6: 18,268,107 (GRCm39) |
I689V |
probably benign |
Het |
| Cgrrf1 |
T |
C |
14: 47,069,785 (GRCm39) |
I18T |
probably damaging |
Het |
| CK137956 |
A |
G |
4: 127,864,519 (GRCm39) |
S37P |
probably damaging |
Het |
| Clca4a |
T |
C |
3: 144,676,416 (GRCm39) |
D88G |
probably benign |
Het |
| Col11a1 |
G |
A |
3: 113,961,141 (GRCm39) |
G1166D |
probably damaging |
Het |
| Col24a1 |
G |
A |
3: 145,166,589 (GRCm39) |
G1075S |
probably damaging |
Het |
| Crispld2 |
C |
T |
8: 120,752,852 (GRCm39) |
T299M |
probably damaging |
Het |
| Cyb561a3 |
T |
A |
19: 10,562,701 (GRCm39) |
Y114N |
probably damaging |
Het |
| Cyp3a57 |
T |
A |
5: 145,307,773 (GRCm39) |
W147R |
possibly damaging |
Het |
| Dnah2 |
C |
A |
11: 69,346,789 (GRCm39) |
R2599L |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,373,207 (GRCm39) |
S525T |
probably benign |
Het |
| Drc7 |
T |
G |
8: 95,789,025 (GRCm39) |
|
probably null |
Het |
| Efhd2 |
G |
T |
4: 141,587,192 (GRCm39) |
|
probably null |
Het |
| Epb41l1 |
A |
T |
2: 156,367,142 (GRCm39) |
E658D |
probably benign |
Het |
| Evi5 |
C |
T |
5: 107,896,184 (GRCm39) |
S753N |
probably benign |
Het |
| Exoc3 |
A |
T |
13: 74,337,319 (GRCm39) |
D427E |
probably benign |
Het |
| Fbxw9 |
A |
G |
8: 85,792,740 (GRCm39) |
D363G |
probably damaging |
Het |
| Fcer2a |
T |
C |
8: 3,732,910 (GRCm39) |
Y277C |
probably damaging |
Het |
| Fstl5 |
A |
T |
3: 76,229,523 (GRCm39) |
Y108F |
probably damaging |
Het |
| Gcn1 |
A |
G |
5: 115,749,108 (GRCm39) |
D1880G |
probably benign |
Het |
| Gm4924 |
T |
A |
10: 82,214,948 (GRCm39) |
Y915* |
probably null |
Het |
| Gpr139 |
T |
A |
7: 118,743,875 (GRCm39) |
I237F |
probably benign |
Het |
| Hao2 |
A |
G |
3: 98,784,498 (GRCm39) |
L289S |
probably damaging |
Het |
| Hexim1 |
A |
G |
11: 103,007,793 (GRCm39) |
S16G |
probably benign |
Het |
| Hmgcs1 |
T |
A |
13: 120,161,535 (GRCm39) |
M109K |
probably damaging |
Het |
| Hs3st4 |
T |
A |
7: 123,996,052 (GRCm39) |
N239K |
possibly damaging |
Het |
| Hsd3b5 |
T |
A |
3: 98,529,328 (GRCm39) |
N101Y |
probably damaging |
Het |
| Idh2 |
G |
A |
7: 79,747,966 (GRCm39) |
P245S |
probably damaging |
Het |
| Irx3 |
A |
G |
8: 92,525,530 (GRCm39) |
|
probably benign |
Het |
| Lilra5 |
A |
T |
7: 4,244,931 (GRCm39) |
D234V |
probably benign |
Het |
| Lrfn5 |
G |
A |
12: 61,886,476 (GRCm39) |
S88N |
probably damaging |
Het |
| Lrp2 |
A |
T |
2: 69,343,721 (GRCm39) |
S879R |
possibly damaging |
Het |
| Lsm11 |
A |
G |
11: 45,824,781 (GRCm39) |
S249P |
probably benign |
Het |
| Ltbp1 |
C |
T |
17: 75,534,187 (GRCm39) |
A543V |
possibly damaging |
Het |
| Mbd1 |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
18: 74,406,645 (GRCm39) |
|
|
Het |
| Mier2 |
C |
T |
10: 79,376,990 (GRCm39) |
|
probably benign |
Het |
| Mup6 |
G |
C |
4: 60,004,093 (GRCm39) |
G70A |
probably benign |
Het |
| Neb |
A |
G |
2: 52,085,732 (GRCm39) |
L5258P |
probably damaging |
Het |
| Nlrc5 |
G |
A |
8: 95,247,857 (GRCm39) |
|
probably benign |
Het |
| Nr6a1 |
A |
T |
2: 38,630,597 (GRCm39) |
F207I |
possibly damaging |
Het |
| Or2y1 |
A |
T |
11: 49,385,632 (GRCm39) |
T91S |
probably benign |
Het |
| Or5k17 |
A |
T |
16: 58,746,867 (GRCm39) |
D22E |
probably benign |
Het |
| Or8b43 |
T |
C |
9: 38,360,731 (GRCm39) |
C188R |
probably damaging |
Het |
| Osbp2 |
A |
G |
11: 3,665,191 (GRCm39) |
V51A |
possibly damaging |
Het |
| Papln |
G |
T |
12: 83,821,723 (GRCm39) |
C317F |
probably damaging |
Het |
| Pdcd7 |
T |
C |
9: 65,265,904 (GRCm39) |
S454P |
probably damaging |
Het |
| Pde4a |
C |
T |
9: 21,116,597 (GRCm39) |
T473I |
probably damaging |
Het |
| Peg10 |
CC |
CCCCATCAGGC |
6: 4,756,350 (GRCm39) |
|
probably benign |
Het |
| Peg10 |
C |
CCCATCAGGA |
6: 4,756,351 (GRCm39) |
|
probably benign |
Het |
| Peg3 |
G |
T |
7: 6,714,385 (GRCm39) |
S279* |
probably null |
Het |
| Rbl1 |
A |
G |
2: 156,994,887 (GRCm39) |
Y929H |
probably damaging |
Het |
| Rsf1 |
G |
GACGGCGGCA |
7: 97,229,116 (GRCm39) |
|
probably benign |
Het |
| Sall3 |
C |
A |
18: 81,017,590 (GRCm39) |
E113* |
probably null |
Het |
| Scn5a |
A |
C |
9: 119,359,089 (GRCm39) |
F653V |
probably damaging |
Het |
| Selenok |
T |
A |
14: 29,692,005 (GRCm39) |
N14K |
possibly damaging |
Het |
| Slc22a20 |
T |
C |
19: 6,021,838 (GRCm39) |
T426A |
probably benign |
Het |
| Slc4a2 |
T |
A |
5: 24,640,007 (GRCm39) |
S563T |
probably damaging |
Het |
| Sspo |
T |
A |
6: 48,464,889 (GRCm39) |
S3798T |
probably benign |
Het |
| Stag3 |
G |
T |
5: 138,302,969 (GRCm39) |
R63L |
possibly damaging |
Het |
| Stard9 |
A |
T |
2: 120,535,667 (GRCm39) |
M3975L |
probably benign |
Het |
| Syne2 |
C |
A |
12: 75,956,040 (GRCm39) |
T582K |
probably damaging |
Het |
| Tas2r109 |
T |
C |
6: 132,957,048 (GRCm39) |
D294G |
probably benign |
Het |
| Tbl1xr1 |
C |
T |
3: 22,245,603 (GRCm39) |
T203M |
possibly damaging |
Het |
| Tbl1xr1 |
T |
A |
3: 22,245,703 (GRCm39) |
|
probably null |
Het |
| Tcf7l2 |
A |
G |
19: 55,730,955 (GRCm39) |
D19G |
probably damaging |
Het |
| Tecta |
A |
G |
9: 42,248,633 (GRCm39) |
V1923A |
possibly damaging |
Het |
| Tg |
T |
A |
15: 66,560,740 (GRCm39) |
M1034K |
probably benign |
Het |
| Ttf2 |
T |
C |
3: 100,876,941 (GRCm39) |
E8G |
possibly damaging |
Het |
| Vps13b |
T |
A |
15: 35,576,541 (GRCm39) |
V983E |
probably damaging |
Het |
| Vps35l |
A |
G |
7: 118,342,898 (GRCm39) |
H32R |
probably damaging |
Het |
| Vwa2 |
T |
C |
19: 56,890,025 (GRCm39) |
V210A |
probably benign |
Het |
| Xkr6 |
T |
A |
14: 64,057,093 (GRCm39) |
Y335N |
probably benign |
Het |
| Zfp97 |
A |
G |
17: 17,365,437 (GRCm39) |
H312R |
probably damaging |
Het |
|
| Other mutations in Synj1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01143:Synj1
|
APN |
16 |
90,748,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01468:Synj1
|
APN |
16 |
90,807,060 (GRCm39) |
splice site |
probably benign |
|
|
IGL02209:Synj1
|
APN |
16 |
90,784,307 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02452:Synj1
|
APN |
16 |
90,758,253 (GRCm39) |
splice site |
probably benign |
|
|
IGL02619:Synj1
|
APN |
16 |
90,770,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02650:Synj1
|
APN |
16 |
90,773,584 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02708:Synj1
|
APN |
16 |
90,788,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02863:Synj1
|
APN |
16 |
90,758,322 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03131:Synj1
|
APN |
16 |
90,785,056 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03295:Synj1
|
APN |
16 |
90,735,318 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL03356:Synj1
|
APN |
16 |
90,784,280 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Synj1
|
UTSW |
16 |
90,761,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0179:Synj1
|
UTSW |
16 |
90,761,519 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0396:Synj1
|
UTSW |
16 |
90,735,528 (GRCm39) |
missense |
probably benign |
|
|
R0426:Synj1
|
UTSW |
16 |
90,764,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0486:Synj1
|
UTSW |
16 |
90,735,151 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R0515:Synj1
|
UTSW |
16 |
90,790,910 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0535:Synj1
|
UTSW |
16 |
90,744,975 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0697:Synj1
|
UTSW |
16 |
90,757,503 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0698:Synj1
|
UTSW |
16 |
90,757,503 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0945:Synj1
|
UTSW |
16 |
90,757,333 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1327:Synj1
|
UTSW |
16 |
90,743,743 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1562:Synj1
|
UTSW |
16 |
90,784,290 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1732:Synj1
|
UTSW |
16 |
90,761,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1752:Synj1
|
UTSW |
16 |
90,735,361 (GRCm39) |
missense |
probably benign |
|
|
R1785:Synj1
|
UTSW |
16 |
90,761,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1786:Synj1
|
UTSW |
16 |
90,761,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2011:Synj1
|
UTSW |
16 |
90,735,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2012:Synj1
|
UTSW |
16 |
90,735,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2065:Synj1
|
UTSW |
16 |
90,788,537 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2862:Synj1
|
UTSW |
16 |
90,766,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3026:Synj1
|
UTSW |
16 |
90,775,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3151:Synj1
|
UTSW |
16 |
90,757,514 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3946:Synj1
|
UTSW |
16 |
90,806,984 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R3971:Synj1
|
UTSW |
16 |
90,788,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4472:Synj1
|
UTSW |
16 |
90,766,069 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4547:Synj1
|
UTSW |
16 |
90,785,170 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4647:Synj1
|
UTSW |
16 |
90,770,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4739:Synj1
|
UTSW |
16 |
90,752,307 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Synj1
|
UTSW |
16 |
90,737,407 (GRCm39) |
splice site |
probably null |
|
|
R5428:Synj1
|
UTSW |
16 |
90,788,406 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5586:Synj1
|
UTSW |
16 |
90,806,865 (GRCm39) |
intron |
probably benign |
|
|
R5769:Synj1
|
UTSW |
16 |
90,735,141 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R6005:Synj1
|
UTSW |
16 |
90,766,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6119:Synj1
|
UTSW |
16 |
90,735,877 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6313:Synj1
|
UTSW |
16 |
90,743,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6324:Synj1
|
UTSW |
16 |
90,735,518 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6549:Synj1
|
UTSW |
16 |
90,735,565 (GRCm39) |
missense |
probably benign |
|
|
R6696:Synj1
|
UTSW |
16 |
90,757,340 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6698:Synj1
|
UTSW |
16 |
90,757,340 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7008:Synj1
|
UTSW |
16 |
90,790,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7153:Synj1
|
UTSW |
16 |
90,744,978 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7393:Synj1
|
UTSW |
16 |
90,748,887 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7510:Synj1
|
UTSW |
16 |
90,735,565 (GRCm39) |
missense |
probably benign |
|
|
R7560:Synj1
|
UTSW |
16 |
90,737,371 (GRCm39) |
missense |
probably benign |
|
|
R7724:Synj1
|
UTSW |
16 |
90,758,387 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7913:Synj1
|
UTSW |
16 |
90,788,315 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8326:Synj1
|
UTSW |
16 |
90,785,084 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8707:Synj1
|
UTSW |
16 |
90,752,319 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8711:Synj1
|
UTSW |
16 |
90,806,971 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8767:Synj1
|
UTSW |
16 |
90,758,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8911:Synj1
|
UTSW |
16 |
90,775,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9052:Synj1
|
UTSW |
16 |
90,735,728 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9124:Synj1
|
UTSW |
16 |
90,735,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9307:Synj1
|
UTSW |
16 |
90,785,095 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9408:Synj1
|
UTSW |
16 |
90,741,740 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9458:Synj1
|
UTSW |
16 |
90,766,200 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9567:Synj1
|
UTSW |
16 |
90,790,912 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9651:Synj1
|
UTSW |
16 |
90,757,343 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9651:Synj1
|
UTSW |
16 |
90,735,412 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9707:Synj1
|
UTSW |
16 |
90,758,300 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9730:Synj1
|
UTSW |
16 |
90,757,552 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9732:Synj1
|
UTSW |
16 |
90,761,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Synj1
|
UTSW |
16 |
90,784,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCAAAATTCATACCCTCCTTTTACA -3'
(R):5'- AGTGCTGATAGTGCAAGCC -3'
Sequencing Primer
(F):5'- GATCTTCAGCATTGCAAGGC -3'
(R):5'- ATAGTGCAAGCCCTTGTGAG -3'
|
| Posted On |
2018-09-12 |
Incidental Mutation