Incidental Mutation 'R6861:Arid1b'
| ID |
535562 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arid1b
|
| Ensembl Gene |
ENSMUSG00000069729 |
| Gene Name |
AT-rich interaction domain 1B |
| Synonyms |
9330189K18Rik, B230217J03Rik |
| MMRRC Submission |
044962-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.813)
|
| Stock # |
R6861 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
5044607-5397931 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 5377961 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 1238
(V1238M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000111463
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092723]
[ENSMUST00000115797]
[ENSMUST00000115799]
[ENSMUST00000232180]
|
| AlphaFold |
E9Q4N7 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000092723
AA Change: V1237M
PolyPhen 2
Score 0.926 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000090398
Gene: ENSMUSG00000069729
AA Change: V1237M
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
69 |
132 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
150 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
232 |
247 |
N/A |
INTRINSIC |
|
low complexity region
|
257 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
371 |
N/A |
INTRINSIC |
|
low complexity region
|
379 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
476 |
N/A |
INTRINSIC |
|
low complexity region
|
485 |
499 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
558 |
N/A |
INTRINSIC |
|
low complexity region
|
574 |
591 |
N/A |
INTRINSIC |
|
low complexity region
|
596 |
611 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
640 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
707 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
740 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
773 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
816 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
952 |
N/A |
INTRINSIC |
|
low complexity region
|
974 |
985 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1045 |
N/A |
INTRINSIC |
|
ARID
|
1057 |
1147 |
9.9e-33 |
SMART |
|
BRIGHT
|
1061 |
1152 |
7.62e-41 |
SMART |
|
low complexity region
|
1166 |
1177 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1268 |
N/A |
INTRINSIC |
|
low complexity region
|
1336 |
1364 |
N/A |
INTRINSIC |
|
low complexity region
|
1426 |
1456 |
N/A |
INTRINSIC |
|
low complexity region
|
1473 |
1486 |
N/A |
INTRINSIC |
|
low complexity region
|
1579 |
1595 |
N/A |
INTRINSIC |
|
coiled coil region
|
1724 |
1745 |
N/A |
INTRINSIC |
|
low complexity region
|
1835 |
1843 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1933 |
2189 |
1.5e-152 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000115797
AA Change: V1238M
PolyPhen 2
Score 0.926 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000111463
Gene: ENSMUSG00000069729
AA Change: V1238M
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
80 |
N/A |
INTRINSIC |
|
low complexity region
|
87 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
149 |
172 |
N/A |
INTRINSIC |
|
low complexity region
|
180 |
195 |
N/A |
INTRINSIC |
|
low complexity region
|
205 |
224 |
N/A |
INTRINSIC |
|
low complexity region
|
249 |
319 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
355 |
N/A |
INTRINSIC |
|
low complexity region
|
386 |
424 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
low complexity region
|
486 |
506 |
N/A |
INTRINSIC |
|
low complexity region
|
522 |
539 |
N/A |
INTRINSIC |
|
low complexity region
|
544 |
559 |
N/A |
INTRINSIC |
|
low complexity region
|
563 |
588 |
N/A |
INTRINSIC |
|
low complexity region
|
639 |
655 |
N/A |
INTRINSIC |
|
low complexity region
|
667 |
688 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
721 |
N/A |
INTRINSIC |
|
low complexity region
|
753 |
764 |
N/A |
INTRINSIC |
|
low complexity region
|
860 |
878 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
922 |
933 |
N/A |
INTRINSIC |
|
Blast:ARID
|
981 |
1028 |
1e-8 |
BLAST |
|
low complexity region
|
1029 |
1054 |
N/A |
INTRINSIC |
|
ARID
|
1058 |
1148 |
9.9e-33 |
SMART |
|
BRIGHT
|
1062 |
1153 |
7.62e-41 |
SMART |
|
low complexity region
|
1167 |
1178 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1269 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1427 |
1457 |
N/A |
INTRINSIC |
|
low complexity region
|
1474 |
1487 |
N/A |
INTRINSIC |
|
low complexity region
|
1580 |
1596 |
N/A |
INTRINSIC |
|
coiled coil region
|
1725 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1836 |
1844 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1935 |
2190 |
6.3e-121 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000115799
AA Change: V756M
PolyPhen 2
Score 0.598 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000111465
Gene: ENSMUSG00000069729
AA Change: V756M
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
54 |
N/A |
INTRINSIC |
|
low complexity region
|
70 |
87 |
N/A |
INTRINSIC |
|
low complexity region
|
92 |
107 |
N/A |
INTRINSIC |
|
low complexity region
|
111 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
187 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
215 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
282 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
418 |
N/A |
INTRINSIC |
|
low complexity region
|
440 |
451 |
N/A |
INTRINSIC |
|
Blast:ARID
|
499 |
546 |
1e-8 |
BLAST |
|
low complexity region
|
547 |
572 |
N/A |
INTRINSIC |
|
ARID
|
576 |
666 |
9.9e-33 |
SMART |
|
BRIGHT
|
580 |
671 |
7.62e-41 |
SMART |
|
low complexity region
|
685 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
776 |
787 |
N/A |
INTRINSIC |
|
low complexity region
|
855 |
883 |
N/A |
INTRINSIC |
|
low complexity region
|
945 |
975 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1005 |
N/A |
INTRINSIC |
|
low complexity region
|
1098 |
1114 |
N/A |
INTRINSIC |
|
coiled coil region
|
1243 |
1264 |
N/A |
INTRINSIC |
|
low complexity region
|
1354 |
1362 |
N/A |
INTRINSIC |
|
Pfam:DUF3518
|
1452 |
1708 |
1.1e-152 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000232180
AA Change: V1290M
PolyPhen 2
Score 0.912 (Sensitivity: 0.81; Specificity: 0.94)
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
|
| Allele List at MGI |
All alleles(61) : Targeted(2) Gene trapped(59)
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl4 |
G |
A |
3: 95,588,194 (GRCm39) |
R598C |
probably damaging |
Het |
| Adra2a |
T |
C |
19: 54,034,818 (GRCm39) |
L58P |
probably damaging |
Het |
| Ajm1 |
C |
CTCTA |
2: 25,469,733 (GRCm39) |
|
probably null |
Het |
| Alox5ap |
A |
G |
5: 149,201,927 (GRCm39) |
D2G |
probably damaging |
Het |
| Bank1 |
A |
G |
3: 135,960,764 (GRCm39) |
V31A |
probably benign |
Het |
| Bptf |
G |
A |
11: 106,953,391 (GRCm39) |
T2117M |
probably damaging |
Het |
| Cadps |
G |
A |
14: 12,522,401 (GRCm38) |
R588* |
probably null |
Het |
| Cavin4 |
A |
G |
4: 48,672,214 (GRCm39) |
I220V |
probably benign |
Het |
| Cep192 |
G |
A |
18: 67,974,699 (GRCm39) |
M1267I |
probably benign |
Het |
| Cers5 |
G |
A |
15: 99,670,244 (GRCm39) |
|
probably benign |
Het |
| Cfap65 |
A |
T |
1: 74,964,274 (GRCm39) |
I558N |
probably damaging |
Het |
| Cfh |
A |
T |
1: 140,028,621 (GRCm39) |
S1025T |
probably benign |
Het |
| Cftr |
A |
G |
6: 18,268,107 (GRCm39) |
I689V |
probably benign |
Het |
| Cgrrf1 |
T |
C |
14: 47,069,785 (GRCm39) |
I18T |
probably damaging |
Het |
| CK137956 |
A |
G |
4: 127,864,519 (GRCm39) |
S37P |
probably damaging |
Het |
| Clca4a |
T |
C |
3: 144,676,416 (GRCm39) |
D88G |
probably benign |
Het |
| Col11a1 |
G |
A |
3: 113,961,141 (GRCm39) |
G1166D |
probably damaging |
Het |
| Col24a1 |
G |
A |
3: 145,166,589 (GRCm39) |
G1075S |
probably damaging |
Het |
| Crispld2 |
C |
T |
8: 120,752,852 (GRCm39) |
T299M |
probably damaging |
Het |
| Cyb561a3 |
T |
A |
19: 10,562,701 (GRCm39) |
Y114N |
probably damaging |
Het |
| Cyp3a57 |
T |
A |
5: 145,307,773 (GRCm39) |
W147R |
possibly damaging |
Het |
| Dnah2 |
C |
A |
11: 69,346,789 (GRCm39) |
R2599L |
possibly damaging |
Het |
| Dock1 |
T |
A |
7: 134,373,207 (GRCm39) |
S525T |
probably benign |
Het |
| Drc7 |
T |
G |
8: 95,789,025 (GRCm39) |
|
probably null |
Het |
| Efhd2 |
G |
T |
4: 141,587,192 (GRCm39) |
|
probably null |
Het |
| Epb41l1 |
A |
T |
2: 156,367,142 (GRCm39) |
E658D |
probably benign |
Het |
| Evi5 |
C |
T |
5: 107,896,184 (GRCm39) |
S753N |
probably benign |
Het |
| Exoc3 |
A |
T |
13: 74,337,319 (GRCm39) |
D427E |
probably benign |
Het |
| Fbxw9 |
A |
G |
8: 85,792,740 (GRCm39) |
D363G |
probably damaging |
Het |
| Fcer2a |
T |
C |
8: 3,732,910 (GRCm39) |
Y277C |
probably damaging |
Het |
| Fstl5 |
A |
T |
3: 76,229,523 (GRCm39) |
Y108F |
probably damaging |
Het |
| Gcn1 |
A |
G |
5: 115,749,108 (GRCm39) |
D1880G |
probably benign |
Het |
| Gm4924 |
T |
A |
10: 82,214,948 (GRCm39) |
Y915* |
probably null |
Het |
| Gpr139 |
T |
A |
7: 118,743,875 (GRCm39) |
I237F |
probably benign |
Het |
| Hao2 |
A |
G |
3: 98,784,498 (GRCm39) |
L289S |
probably damaging |
Het |
| Hexim1 |
A |
G |
11: 103,007,793 (GRCm39) |
S16G |
probably benign |
Het |
| Hmgcs1 |
T |
A |
13: 120,161,535 (GRCm39) |
M109K |
probably damaging |
Het |
| Hs3st4 |
T |
A |
7: 123,996,052 (GRCm39) |
N239K |
possibly damaging |
Het |
| Hsd3b5 |
T |
A |
3: 98,529,328 (GRCm39) |
N101Y |
probably damaging |
Het |
| Idh2 |
G |
A |
7: 79,747,966 (GRCm39) |
P245S |
probably damaging |
Het |
| Irx3 |
A |
G |
8: 92,525,530 (GRCm39) |
|
probably benign |
Het |
| Lilra5 |
A |
T |
7: 4,244,931 (GRCm39) |
D234V |
probably benign |
Het |
| Lrfn5 |
G |
A |
12: 61,886,476 (GRCm39) |
S88N |
probably damaging |
Het |
| Lrp2 |
A |
T |
2: 69,343,721 (GRCm39) |
S879R |
possibly damaging |
Het |
| Lsm11 |
A |
G |
11: 45,824,781 (GRCm39) |
S249P |
probably benign |
Het |
| Ltbp1 |
C |
T |
17: 75,534,187 (GRCm39) |
A543V |
possibly damaging |
Het |
| Mbd1 |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
GTCTGCATCTGCGTCTTCGTCTGCATCTGCATCTGC |
18: 74,406,645 (GRCm39) |
|
|
Het |
| Mier2 |
C |
T |
10: 79,376,990 (GRCm39) |
|
probably benign |
Het |
| Mup6 |
G |
C |
4: 60,004,093 (GRCm39) |
G70A |
probably benign |
Het |
| Neb |
A |
G |
2: 52,085,732 (GRCm39) |
L5258P |
probably damaging |
Het |
| Nlrc5 |
G |
A |
8: 95,247,857 (GRCm39) |
|
probably benign |
Het |
| Nr6a1 |
A |
T |
2: 38,630,597 (GRCm39) |
F207I |
possibly damaging |
Het |
| Or2y1 |
A |
T |
11: 49,385,632 (GRCm39) |
T91S |
probably benign |
Het |
| Or5k17 |
A |
T |
16: 58,746,867 (GRCm39) |
D22E |
probably benign |
Het |
| Or8b43 |
T |
C |
9: 38,360,731 (GRCm39) |
C188R |
probably damaging |
Het |
| Osbp2 |
A |
G |
11: 3,665,191 (GRCm39) |
V51A |
possibly damaging |
Het |
| Papln |
G |
T |
12: 83,821,723 (GRCm39) |
C317F |
probably damaging |
Het |
| Pdcd7 |
T |
C |
9: 65,265,904 (GRCm39) |
S454P |
probably damaging |
Het |
| Pde4a |
C |
T |
9: 21,116,597 (GRCm39) |
T473I |
probably damaging |
Het |
| Peg10 |
CC |
CCCCATCAGGC |
6: 4,756,350 (GRCm39) |
|
probably benign |
Het |
| Peg10 |
C |
CCCATCAGGA |
6: 4,756,351 (GRCm39) |
|
probably benign |
Het |
| Peg3 |
G |
T |
7: 6,714,385 (GRCm39) |
S279* |
probably null |
Het |
| Rbl1 |
A |
G |
2: 156,994,887 (GRCm39) |
Y929H |
probably damaging |
Het |
| Rsf1 |
G |
GACGGCGGCA |
7: 97,229,116 (GRCm39) |
|
probably benign |
Het |
| Sall3 |
C |
A |
18: 81,017,590 (GRCm39) |
E113* |
probably null |
Het |
| Scn5a |
A |
C |
9: 119,359,089 (GRCm39) |
F653V |
probably damaging |
Het |
| Selenok |
T |
A |
14: 29,692,005 (GRCm39) |
N14K |
possibly damaging |
Het |
| Slc22a20 |
T |
C |
19: 6,021,838 (GRCm39) |
T426A |
probably benign |
Het |
| Slc4a2 |
T |
A |
5: 24,640,007 (GRCm39) |
S563T |
probably damaging |
Het |
| Sspo |
T |
A |
6: 48,464,889 (GRCm39) |
S3798T |
probably benign |
Het |
| Stag3 |
G |
T |
5: 138,302,969 (GRCm39) |
R63L |
possibly damaging |
Het |
| Stard9 |
A |
T |
2: 120,535,667 (GRCm39) |
M3975L |
probably benign |
Het |
| Syne2 |
C |
A |
12: 75,956,040 (GRCm39) |
T582K |
probably damaging |
Het |
| Synj1 |
G |
A |
16: 90,760,768 (GRCm39) |
Q748* |
probably null |
Het |
| Tas2r109 |
T |
C |
6: 132,957,048 (GRCm39) |
D294G |
probably benign |
Het |
| Tbl1xr1 |
C |
T |
3: 22,245,603 (GRCm39) |
T203M |
possibly damaging |
Het |
| Tbl1xr1 |
T |
A |
3: 22,245,703 (GRCm39) |
|
probably null |
Het |
| Tcf7l2 |
A |
G |
19: 55,730,955 (GRCm39) |
D19G |
probably damaging |
Het |
| Tecta |
A |
G |
9: 42,248,633 (GRCm39) |
V1923A |
possibly damaging |
Het |
| Tg |
T |
A |
15: 66,560,740 (GRCm39) |
M1034K |
probably benign |
Het |
| Ttf2 |
T |
C |
3: 100,876,941 (GRCm39) |
E8G |
possibly damaging |
Het |
| Vps13b |
T |
A |
15: 35,576,541 (GRCm39) |
V983E |
probably damaging |
Het |
| Vps35l |
A |
G |
7: 118,342,898 (GRCm39) |
H32R |
probably damaging |
Het |
| Vwa2 |
T |
C |
19: 56,890,025 (GRCm39) |
V210A |
probably benign |
Het |
| Xkr6 |
T |
A |
14: 64,057,093 (GRCm39) |
Y335N |
probably benign |
Het |
| Zfp97 |
A |
G |
17: 17,365,437 (GRCm39) |
H312R |
probably damaging |
Het |
|
| Other mutations in Arid1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Arid1b
|
APN |
17 |
5,387,385 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL00340:Arid1b
|
APN |
17 |
5,371,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00886:Arid1b
|
APN |
17 |
5,177,254 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01161:Arid1b
|
APN |
17 |
5,392,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01391:Arid1b
|
APN |
17 |
5,369,133 (GRCm39) |
splice site |
probably benign |
|
|
IGL01456:Arid1b
|
APN |
17 |
5,341,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02152:Arid1b
|
APN |
17 |
5,364,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02288:Arid1b
|
APN |
17 |
5,314,315 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02713:Arid1b
|
APN |
17 |
5,393,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02858:Arid1b
|
APN |
17 |
5,392,166 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02885:Arid1b
|
APN |
17 |
5,392,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02989:Arid1b
|
APN |
17 |
5,385,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4449:Arid1b
|
UTSW |
17 |
5,045,864 (GRCm39) |
small insertion |
probably benign |
|
|
PIT4142001:Arid1b
|
UTSW |
17 |
5,389,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Arid1b
|
UTSW |
17 |
5,364,309 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0124:Arid1b
|
UTSW |
17 |
5,389,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0153:Arid1b
|
UTSW |
17 |
5,393,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Arid1b
|
UTSW |
17 |
5,046,535 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R0825:Arid1b
|
UTSW |
17 |
5,392,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1172:Arid1b
|
UTSW |
17 |
5,389,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1468:Arid1b
|
UTSW |
17 |
5,293,197 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1616:Arid1b
|
UTSW |
17 |
5,389,569 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Arid1b
|
UTSW |
17 |
5,329,476 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1760:Arid1b
|
UTSW |
17 |
5,392,088 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1812:Arid1b
|
UTSW |
17 |
5,387,304 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1911:Arid1b
|
UTSW |
17 |
5,393,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3874:Arid1b
|
UTSW |
17 |
5,386,790 (GRCm39) |
splice site |
probably null |
|
|
R3913:Arid1b
|
UTSW |
17 |
5,392,532 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3916:Arid1b
|
UTSW |
17 |
5,392,928 (GRCm39) |
missense |
probably benign |
0.25 |
|
R3922:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4119:Arid1b
|
UTSW |
17 |
5,046,069 (GRCm39) |
unclassified |
probably benign |
|
|
R4290:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4291:Arid1b
|
UTSW |
17 |
5,090,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4352:Arid1b
|
UTSW |
17 |
5,147,859 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4386:Arid1b
|
UTSW |
17 |
5,045,247 (GRCm39) |
unclassified |
probably benign |
|
|
R4458:Arid1b
|
UTSW |
17 |
5,293,191 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4524:Arid1b
|
UTSW |
17 |
5,147,895 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4622:Arid1b
|
UTSW |
17 |
5,045,325 (GRCm39) |
unclassified |
probably benign |
|
|
R4723:Arid1b
|
UTSW |
17 |
5,387,565 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4782:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Arid1b
|
UTSW |
17 |
5,389,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4910:Arid1b
|
UTSW |
17 |
5,392,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4946:Arid1b
|
UTSW |
17 |
5,393,118 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5083:Arid1b
|
UTSW |
17 |
5,364,293 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R5204:Arid1b
|
UTSW |
17 |
5,393,316 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5347:Arid1b
|
UTSW |
17 |
5,341,332 (GRCm39) |
nonsense |
probably null |
|
|
R5553:Arid1b
|
UTSW |
17 |
5,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5713:Arid1b
|
UTSW |
17 |
5,387,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5820:Arid1b
|
UTSW |
17 |
5,046,529 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5992:Arid1b
|
UTSW |
17 |
5,045,231 (GRCm39) |
unclassified |
probably benign |
|
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6038:Arid1b
|
UTSW |
17 |
5,386,957 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6153:Arid1b
|
UTSW |
17 |
5,293,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6222:Arid1b
|
UTSW |
17 |
5,377,922 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6249:Arid1b
|
UTSW |
17 |
5,329,636 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R6279:Arid1b
|
UTSW |
17 |
5,392,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6329:Arid1b
|
UTSW |
17 |
5,387,538 (GRCm39) |
nonsense |
probably null |
|
|
R6368:Arid1b
|
UTSW |
17 |
5,382,808 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R6466:Arid1b
|
UTSW |
17 |
5,377,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7008:Arid1b
|
UTSW |
17 |
5,341,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7270:Arid1b
|
UTSW |
17 |
5,046,318 (GRCm39) |
missense |
unknown |
|
|
R7514:Arid1b
|
UTSW |
17 |
5,391,989 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7519:Arid1b
|
UTSW |
17 |
5,046,128 (GRCm39) |
small insertion |
probably benign |
|
|
R7519:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,392,865 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7521:Arid1b
|
UTSW |
17 |
5,046,119 (GRCm39) |
small insertion |
probably benign |
|
|
R7521:Arid1b
|
UTSW |
17 |
5,046,135 (GRCm39) |
small insertion |
probably benign |
|
|
R7616:Arid1b
|
UTSW |
17 |
5,045,661 (GRCm39) |
missense |
unknown |
|
|
R7654:Arid1b
|
UTSW |
17 |
5,341,360 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7711:Arid1b
|
UTSW |
17 |
5,387,095 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7828:Arid1b
|
UTSW |
17 |
5,147,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7864:Arid1b
|
UTSW |
17 |
5,392,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7998:Arid1b
|
UTSW |
17 |
5,377,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8105:Arid1b
|
UTSW |
17 |
5,341,518 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8260:Arid1b
|
UTSW |
17 |
5,382,788 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8374:Arid1b
|
UTSW |
17 |
5,392,919 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8779:Arid1b
|
UTSW |
17 |
5,391,809 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8801:Arid1b
|
UTSW |
17 |
5,387,103 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8894:Arid1b
|
UTSW |
17 |
5,377,668 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8982:Arid1b
|
UTSW |
17 |
5,293,316 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9034:Arid1b
|
UTSW |
17 |
5,387,180 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9272:Arid1b
|
UTSW |
17 |
5,386,879 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9300:Arid1b
|
UTSW |
17 |
5,293,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Arid1b
|
UTSW |
17 |
5,045,584 (GRCm39) |
missense |
unknown |
|
|
R9481:Arid1b
|
UTSW |
17 |
5,369,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9493:Arid1b
|
UTSW |
17 |
5,046,423 (GRCm39) |
missense |
unknown |
|
|
R9512:Arid1b
|
UTSW |
17 |
5,391,864 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9548:Arid1b
|
UTSW |
17 |
5,385,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF007:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF008:Arid1b
|
UTSW |
17 |
5,045,869 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,871 (GRCm39) |
small insertion |
probably benign |
|
|
RF025:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF028:Arid1b
|
UTSW |
17 |
5,045,873 (GRCm39) |
small insertion |
probably benign |
|
|
RF032:Arid1b
|
UTSW |
17 |
5,045,863 (GRCm39) |
small insertion |
probably benign |
|
|
RF033:Arid1b
|
UTSW |
17 |
5,045,860 (GRCm39) |
small insertion |
probably benign |
|
|
RF041:Arid1b
|
UTSW |
17 |
5,045,870 (GRCm39) |
small insertion |
probably benign |
|
|
RF045:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
RF046:Arid1b
|
UTSW |
17 |
5,045,865 (GRCm39) |
small insertion |
probably benign |
|
|
RF058:Arid1b
|
UTSW |
17 |
5,045,858 (GRCm39) |
small insertion |
probably benign |
|
|
X0023:Arid1b
|
UTSW |
17 |
5,392,668 (GRCm39) |
missense |
probably benign |
0.39 |
|
X0027:Arid1b
|
UTSW |
17 |
5,392,647 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Arid1b
|
UTSW |
17 |
5,046,603 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTACTGCTCCTTTCAGCGTG -3'
(R):5'- ACATGGCAGGGGCTTAGAAC -3'
Sequencing Primer
(F):5'- GCTCCTTTCAGCGTGTAGTTTAC -3'
(R):5'- GGCTTAGAACCGTCCCAACTG -3'
|
| Posted On |
2018-09-12 |
Incidental Mutation