Mutagenetix > Incidental Mutation

Incidental Mutation 'R6863:Csmd1'

535751

Institutional Source

Beutler Lab

Gene Symbol

Csmd1

Ensembl Gene

ENSMUSG00000060924

Gene Name

CUB and Sushi multiple domains 1

Synonyms

MMRRC Submission

044963-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R6863 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

15942537-17585602 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 17584929 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Alanine to Valine at position 21 (A21V)

Ref Sequence

ENSEMBL: ENSMUSP00000080751 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000082104]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000082104
AA Change: A21V

PolyPhen 2 Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000080751
Gene: ENSMUSG00000060924
AA Change: A21V

Domain	Start	End	E-Value	Type
signal peptide	1	29	N/A	INTRINSIC
CUB	32	140	1.46e-26	SMART
CCP	145	202	1.01e-11	SMART
CUB	208	312	1.05e-27	SMART
CCP	349	406	1.28e-8	SMART
CUB	411	522	2.34e-25	SMART
CCP	527	580	1.22e-14	SMART
CUB	584	692	1.61e-37	SMART
CCP	697	754	4.41e-12	SMART
CUB	758	866	6.55e-38	SMART
CCP	873	926	2.53e-12	SMART
CUB	930	1040	8.94e-22	SMART
CCP	1045	1100	7.06e-11	SMART
CUB	1104	1212	3.14e-26	SMART
CCP	1217	1273	1.18e-12	SMART
CUB	1277	1386	9.72e-32	SMART
CCP	1391	1447	2.06e-12	SMART
CUB	1451	1559	1.68e-35	SMART
CCP	1564	1621	2.53e-12	SMART
CUB	1625	1733	4.24e-14	SMART
CCP	1741	1798	9.46e-12	SMART
CUB	1802	1910	4.23e-32	SMART
CCP	1915	1970	8.23e-12	SMART
CUB	1974	2082	8.59e-33	SMART
CCP	2087	2142	6.09e-15	SMART
CUB	2146	2253	2.36e-30	SMART
CCP	2258	2315	1.1e-12	SMART
CUB	2320	2430	4.3e-24	SMART
CCP	2432	2490	2.94e-8	SMART
CCP	2495	2552	2.03e-11	SMART
CCP	2557	2617	1.22e-5	SMART
CCP	2622	2675	2.72e-12	SMART
CCP	2680	2733	5.86e-17	SMART
CCP	2738	2791	6.09e-15	SMART
CCP	2796	2854	9.1e-14	SMART
CCP	2859	2912	3.96e-14	SMART
CCP	2920	2973	4.41e-12	SMART
CCP	2978	3032	2.94e-8	SMART
CCP	3037	3092	6.59e-11	SMART
CCP	3097	3150	4.12e-12	SMART
CCP	3155	3208	7.92e-14	SMART
CCP	3216	3270	2.8e-14	SMART
CCP	3275	3330	3.78e-11	SMART
transmembrane domain	3487	3509	N/A	INTRINSIC

Meta Mutation Damage Score

0.1289

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.4%
20x: 97.9%

Validation Efficiency

100% (56/56)

MGI Phenotype

PHENOTYPE: Mice exhibit normal pre-pulse inhibition, social interaction, sucrose preference and d-amphetamine sensitivity. [provided by MGI curators]

Allele List at MGI

All alleles(1) : Targeted, knock-out(1)

Other mutations in this stock

Total: 57 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamts20	A	T	15: 94,277,627 (GRCm39)	Y278*	probably null	Het
Agap3	A	T	5: 24,657,461 (GRCm39)	Y86F	possibly damaging	Het
Agap3	C	A	5: 24,657,462 (GRCm39)	Y86*	probably null	Het
Ahnak	T	C	19: 8,989,729 (GRCm39)		probably benign	Het
Arhgap45	G	T	10: 79,853,616 (GRCm39)	E43D	probably benign	Het
Cacna1d	A	C	14: 29,797,809 (GRCm39)	I1426S	probably damaging	Het
Calhm5	C	A	10: 33,968,451 (GRCm39)	A201S	probably benign	Het
Cdkn2a	T	C	4: 89,193,003 (GRCm39)	E159G	probably benign	Het
Cep85l	C	A	10: 53,225,214 (GRCm39)	W125L	probably damaging	Het
Ces1g	C	T	8: 94,043,647 (GRCm39)	V431M	possibly damaging	Het
Ctsc	T	A	7: 87,951,486 (GRCm39)	Y243*	probably null	Het
Ctu1	A	G	7: 43,326,046 (GRCm39)	E235G	probably damaging	Het
Degs2	T	C	12: 108,668,457 (GRCm39)	Y14C	probably damaging	Het
Dnaaf5	T	C	5: 139,137,351 (GRCm39)	F235L	probably damaging	Het
Dpp8	T	C	9: 64,942,290 (GRCm39)	S5P	probably damaging	Het
Dync1h1	T	C	12: 110,618,614 (GRCm39)	I3288T	probably benign	Het
Ebpl	A	T	14: 61,597,751 (GRCm39)	L30Q	probably damaging	Het
Eif1ad15	T	C	12: 88,287,968 (GRCm39)	Y95C	probably damaging	Het
Etaa1	T	A	11: 17,903,794 (GRCm39)	M1L	probably benign	Het
Etl4	A	G	2: 20,811,120 (GRCm39)	T1068A	probably benign	Het
Eya1	C	A	1: 14,341,199 (GRCm39)		probably null	Het
Fat1	G	T	8: 45,497,501 (GRCm39)	V4329L	probably damaging	Het
Fras1	A	T	5: 96,691,165 (GRCm39)	Q127L	probably benign	Het
Gm1110	T	G	9: 26,792,360 (GRCm39)	Y590S	probably damaging	Het
Gm14410	G	A	2: 176,885,860 (GRCm39)	Q135*	probably null	Het
Greb1	A	T	12: 16,734,421 (GRCm39)	V1523D	probably damaging	Het
Hmg20b	T	C	10: 81,182,854 (GRCm39)	N210S	probably damaging	Het
Kcnh7	T	C	2: 62,618,029 (GRCm39)	K487E	possibly damaging	Het
Kcnk13	G	T	12: 100,027,948 (GRCm39)	R341L	probably damaging	Het
Kif17	T	A	4: 137,997,195 (GRCm39)	Y139*	probably null	Het
Klhl2	A	T	8: 65,275,743 (GRCm39)	N53K	probably benign	Het
Lrit2	G	T	14: 36,793,901 (GRCm39)	G322C	probably damaging	Het
Macir	T	C	1: 97,574,030 (GRCm39)	T12A	probably benign	Het
Matcap1	T	C	8: 106,012,435 (GRCm39)	D4G	probably damaging	Het
Mgam	A	T	6: 40,705,943 (GRCm39)	Q4L	probably benign	Het
Mst1r	A	G	9: 107,797,225 (GRCm39)	T1365A	probably benign	Het
Muc5ac	C	T	7: 141,363,481 (GRCm39)		probably benign	Het
Mydgf	C	A	17: 56,490,789 (GRCm39)	V35L	probably damaging	Het
Nmt2	T	A	2: 3,306,341 (GRCm39)		probably null	Het
Or10s1	A	G	9: 39,986,110 (GRCm39)	Y173C	probably damaging	Het
Or52ad1	C	T	7: 102,996,123 (GRCm39)	C4Y	possibly damaging	Het
Pik3r2	T	C	8: 71,223,058 (GRCm39)	Y454C	probably damaging	Het
Rad54l	T	C	4: 115,956,866 (GRCm39)	Y485C	probably damaging	Het
Rapgef6	T	A	11: 54,437,206 (GRCm39)	S50T	probably benign	Het
Scaf11	T	C	15: 96,317,300 (GRCm39)	S755G	probably damaging	Het
Shb	A	G	4: 45,458,163 (GRCm39)	W135R	probably damaging	Het
Slc1a4	T	C	11: 20,264,001 (GRCm39)	K239E	probably damaging	Het
Slc44a4	T	A	17: 35,142,798 (GRCm39)	V248D	probably benign	Het
Smpdl3a	T	A	10: 57,684,107 (GRCm39)	Y288*	probably null	Het
Sptbn1	T	C	11: 30,096,777 (GRCm39)	M267V	possibly damaging	Het
Taok2	C	T	7: 126,471,109 (GRCm39)	R661Q	probably damaging	Het
Tas1r2	A	T	4: 139,397,030 (GRCm39)	I819F	probably damaging	Het
Themis2	A	T	4: 132,516,907 (GRCm39)	W198R	probably damaging	Het
Timd4	C	G	11: 46,706,270 (GRCm39)	S24*	probably null	Het
Tnrc18	T	C	5: 142,800,952 (GRCm39)	D2G	probably damaging	Het
Wdr35	A	G	12: 9,040,047 (GRCm39)	D384G	probably damaging	Het
Zfp560	C	A	9: 20,259,795 (GRCm39)	V356F	probably damaging	Het

Other mutations in Csmd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00095:Csmd1	APN	8	16,059,297 (GRCm39)	splice site	probably benign
IGL00433:Csmd1	APN	8	16,281,387 (GRCm39)	missense	probably damaging	1.00
IGL00500:Csmd1	APN	8	15,971,139 (GRCm39)	missense	probably damaging	1.00
IGL00666:Csmd1	APN	8	16,240,004 (GRCm39)	missense	probably damaging	1.00
IGL00913:Csmd1	APN	8	16,121,301 (GRCm39)	missense	probably benign	0.00
IGL01012:Csmd1	APN	8	15,967,341 (GRCm39)	missense	probably benign	0.00
IGL01123:Csmd1	APN	8	17,584,944 (GRCm39)	missense	possibly damaging	0.96
IGL01348:Csmd1	APN	8	15,960,596 (GRCm39)	missense	probably damaging	0.99
IGL01444:Csmd1	APN	8	16,250,069 (GRCm39)	missense	probably benign	0.00
IGL01530:Csmd1	APN	8	15,953,195 (GRCm39)	missense	probably damaging	0.99
IGL01548:Csmd1	APN	8	16,338,660 (GRCm39)	nonsense	probably null
IGL01814:Csmd1	APN	8	16,551,389 (GRCm39)	missense	probably damaging	1.00
IGL01889:Csmd1	APN	8	16,048,857 (GRCm39)	missense	probably damaging	1.00
IGL02055:Csmd1	APN	8	16,119,015 (GRCm39)	missense	probably damaging	0.99
IGL02066:Csmd1	APN	8	15,976,594 (GRCm39)	missense	probably damaging	1.00
IGL02097:Csmd1	APN	8	16,261,773 (GRCm39)	missense	probably null	0.17
IGL02112:Csmd1	APN	8	16,131,719 (GRCm39)	missense	probably benign	0.18
IGL02161:Csmd1	APN	8	16,408,426 (GRCm39)	missense	probably damaging	0.97
IGL02189:Csmd1	APN	8	16,321,620 (GRCm39)	missense	probably damaging	0.99
IGL02272:Csmd1	APN	8	16,249,907 (GRCm39)	missense	probably damaging	0.99
IGL02292:Csmd1	APN	8	16,261,884 (GRCm39)	missense	probably damaging	1.00
IGL02385:Csmd1	APN	8	15,953,275 (GRCm39)	missense	probably benign	0.08
IGL02424:Csmd1	APN	8	16,142,340 (GRCm39)	missense	probably benign	0.22
IGL02492:Csmd1	APN	8	16,052,597 (GRCm39)	missense	probably benign	0.13
IGL02507:Csmd1	APN	8	17,584,992 (GRCm39)	utr 5 prime	probably benign
IGL02513:Csmd1	APN	8	16,049,869 (GRCm39)	splice site	probably benign
IGL02727:Csmd1	APN	8	16,281,341 (GRCm39)	missense	probably damaging	1.00
IGL02728:Csmd1	APN	8	16,049,779 (GRCm39)	critical splice donor site	probably null
IGL02852:Csmd1	APN	8	15,945,728 (GRCm39)	missense	probably damaging	0.99
IGL02935:Csmd1	APN	8	16,273,348 (GRCm39)	missense	probably damaging	1.00
IGL02945:Csmd1	APN	8	16,321,584 (GRCm39)	missense	possibly damaging	0.92
IGL02959:Csmd1	APN	8	15,960,465 (GRCm39)	missense	probably damaging	0.99
IGL03113:Csmd1	APN	8	16,078,712 (GRCm39)	missense	probably benign
IGL03129:Csmd1	APN	8	16,011,521 (GRCm39)	missense	probably damaging	0.99
IGL03131:Csmd1	APN	8	16,138,231 (GRCm39)	missense	probably damaging	1.00
IGL03275:Csmd1	APN	8	16,207,106 (GRCm39)	missense	probably benign	0.00
IGL03297:Csmd1	APN	8	16,059,432 (GRCm39)	nonsense	probably null
ikura	UTSW	8	16,281,285 (GRCm39)	missense	probably damaging	1.00
I2289:Csmd1	UTSW	8	15,962,381 (GRCm39)	missense	probably benign	0.10
IGL03055:Csmd1	UTSW	8	16,145,515 (GRCm39)	missense	probably damaging	1.00
IGL03097:Csmd1	UTSW	8	15,995,127 (GRCm39)	missense	probably damaging	1.00
PIT4260001:Csmd1	UTSW	8	16,120,327 (GRCm39)	missense	probably damaging	1.00
PIT4378001:Csmd1	UTSW	8	15,945,728 (GRCm39)	missense	probably damaging	0.99
PIT4520001:Csmd1	UTSW	8	15,956,023 (GRCm39)	missense	probably benign	0.01
R0037:Csmd1	UTSW	8	15,967,248 (GRCm39)	missense	probably damaging	0.97
R0095:Csmd1	UTSW	8	16,283,065 (GRCm39)	missense	probably damaging	1.00
R0113:Csmd1	UTSW	8	16,034,849 (GRCm39)	missense	probably damaging	1.00
R0129:Csmd1	UTSW	8	16,129,956 (GRCm39)	missense	possibly damaging	0.95
R0144:Csmd1	UTSW	8	16,441,838 (GRCm39)	missense	probably benign	0.16
R0166:Csmd1	UTSW	8	16,283,036 (GRCm39)	missense	probably benign	0.29
R0227:Csmd1	UTSW	8	16,441,836 (GRCm39)	missense	probably benign	0.05
R0279:Csmd1	UTSW	8	16,273,249 (GRCm39)	missense	probably damaging	0.99
R0280:Csmd1	UTSW	8	16,321,616 (GRCm39)	missense	probably damaging	1.00
R0312:Csmd1	UTSW	8	16,034,760 (GRCm39)	missense	probably damaging	1.00
R0355:Csmd1	UTSW	8	15,968,330 (GRCm39)	missense	probably damaging	0.97
R0367:Csmd1	UTSW	8	15,967,270 (GRCm39)	missense	probably damaging	1.00
R0395:Csmd1	UTSW	8	16,396,652 (GRCm39)	missense	probably damaging	0.99
R0413:Csmd1	UTSW	8	16,760,530 (GRCm39)	missense	probably damaging	0.97
R0457:Csmd1	UTSW	8	16,551,407 (GRCm39)	critical splice acceptor site	probably null
R0463:Csmd1	UTSW	8	15,971,759 (GRCm39)	missense	probably damaging	0.99
R0482:Csmd1	UTSW	8	16,283,115 (GRCm39)	missense	probably damaging	1.00
R0501:Csmd1	UTSW	8	17,077,339 (GRCm39)	missense	probably damaging	0.97
R0505:Csmd1	UTSW	8	16,042,758 (GRCm39)	missense	probably damaging	1.00
R0507:Csmd1	UTSW	8	16,235,358 (GRCm39)	splice site	probably benign
R0511:Csmd1	UTSW	8	15,982,529 (GRCm39)	missense	possibly damaging	0.80
R0555:Csmd1	UTSW	8	16,235,287 (GRCm39)	missense	probably benign
R0580:Csmd1	UTSW	8	15,960,528 (GRCm39)	missense	probably damaging	1.00
R0610:Csmd1	UTSW	8	15,968,208 (GRCm39)	missense	possibly damaging	0.95
R0634:Csmd1	UTSW	8	16,276,405 (GRCm39)	missense	probably damaging	1.00
R0666:Csmd1	UTSW	8	16,119,063 (GRCm39)	missense	possibly damaging	0.88
R0674:Csmd1	UTSW	8	16,050,550 (GRCm39)	missense	probably benign	0.03
R0675:Csmd1	UTSW	8	16,208,145 (GRCm39)	missense	probably benign	0.01
R0763:Csmd1	UTSW	8	17,077,300 (GRCm39)	missense	possibly damaging	0.67
R0781:Csmd1	UTSW	8	15,971,174 (GRCm39)	missense	probably benign	0.35
R0862:Csmd1	UTSW	8	16,240,040 (GRCm39)	missense	probably damaging	0.99
R0864:Csmd1	UTSW	8	16,240,040 (GRCm39)	missense	probably damaging	0.99
R0925:Csmd1	UTSW	8	16,760,634 (GRCm39)	missense	probably benign	0.29
R0926:Csmd1	UTSW	8	16,083,590 (GRCm39)	splice site	probably null
R1005:Csmd1	UTSW	8	16,338,707 (GRCm39)	missense	probably damaging	0.99
R1073:Csmd1	UTSW	8	16,408,477 (GRCm39)	splice site	probably benign
R1185:Csmd1	UTSW	8	16,408,362 (GRCm39)	missense	probably damaging	0.96
R1185:Csmd1	UTSW	8	16,408,362 (GRCm39)	missense	probably damaging	0.96
R1185:Csmd1	UTSW	8	16,408,362 (GRCm39)	missense	probably damaging	0.96
R1256:Csmd1	UTSW	8	16,129,978 (GRCm39)	missense	probably damaging	1.00
R1294:Csmd1	UTSW	8	16,748,052 (GRCm39)	missense	probably damaging	0.99
R1375:Csmd1	UTSW	8	16,513,095 (GRCm39)	splice site	probably null
R1447:Csmd1	UTSW	8	15,975,306 (GRCm39)	nonsense	probably null
R1450:Csmd1	UTSW	8	15,995,180 (GRCm39)	critical splice acceptor site	probably null
R1470:Csmd1	UTSW	8	16,207,218 (GRCm39)	splice site	probably benign
R1580:Csmd1	UTSW	8	15,975,299 (GRCm39)	missense	probably damaging	1.00
R1591:Csmd1	UTSW	8	15,950,710 (GRCm39)	missense	probably damaging	0.99
R1658:Csmd1	UTSW	8	16,131,739 (GRCm39)	missense	possibly damaging	0.69
R1678:Csmd1	UTSW	8	15,968,252 (GRCm39)	missense	possibly damaging	0.58
R1717:Csmd1	UTSW	8	17,266,708 (GRCm39)	missense	possibly damaging	0.58
R1735:Csmd1	UTSW	8	15,982,610 (GRCm39)	missense	probably damaging	0.99
R1750:Csmd1	UTSW	8	15,967,303 (GRCm39)	missense	probably damaging	0.99
R1753:Csmd1	UTSW	8	16,207,134 (GRCm39)	nonsense	probably null
R1822:Csmd1	UTSW	8	16,273,340 (GRCm39)	missense	probably damaging	1.00
R1875:Csmd1	UTSW	8	15,979,101 (GRCm39)	missense	probably damaging	0.99
R1909:Csmd1	UTSW	8	15,956,116 (GRCm39)	missense	probably damaging	1.00
R1912:Csmd1	UTSW	8	16,284,012 (GRCm39)	critical splice donor site	probably null
R1993:Csmd1	UTSW	8	16,396,698 (GRCm39)	missense	probably damaging	0.99
R2067:Csmd1	UTSW	8	15,950,782 (GRCm39)	missense	probably benign
R2094:Csmd1	UTSW	8	16,129,992 (GRCm39)	missense	probably damaging	0.99
R2119:Csmd1	UTSW	8	17,266,749 (GRCm39)	missense	probably damaging	0.98
R2127:Csmd1	UTSW	8	15,967,392 (GRCm39)	missense	probably damaging	1.00
R2138:Csmd1	UTSW	8	15,979,088 (GRCm39)	missense	probably damaging	0.96
R2216:Csmd1	UTSW	8	17,077,355 (GRCm39)	critical splice acceptor site	probably null
R2220:Csmd1	UTSW	8	16,042,641 (GRCm39)	missense	possibly damaging	0.94
R2380:Csmd1	UTSW	8	16,240,101 (GRCm39)	missense	probably damaging	1.00
R2471:Csmd1	UTSW	8	16,261,776 (GRCm39)	missense	probably damaging	1.00
R2984:Csmd1	UTSW	8	16,003,782 (GRCm39)	missense	probably damaging	1.00
R3001:Csmd1	UTSW	8	16,246,184 (GRCm39)	missense	probably damaging	0.98
R3002:Csmd1	UTSW	8	16,246,184 (GRCm39)	missense	probably damaging	0.98
R3003:Csmd1	UTSW	8	16,246,184 (GRCm39)	missense	probably damaging	0.98
R3103:Csmd1	UTSW	8	15,967,405 (GRCm39)	missense	probably damaging	1.00
R3104:Csmd1	UTSW	8	17,077,247 (GRCm39)	missense	probably damaging	1.00
R3620:Csmd1	UTSW	8	16,042,684 (GRCm39)	missense	probably benign	0.29
R3621:Csmd1	UTSW	8	16,042,684 (GRCm39)	missense	probably benign	0.29
R3748:Csmd1	UTSW	8	15,956,071 (GRCm39)	missense	probably damaging	0.99
R3780:Csmd1	UTSW	8	16,252,000 (GRCm39)	missense	probably damaging	1.00
R3815:Csmd1	UTSW	8	16,052,522 (GRCm39)	missense	probably damaging	1.00
R3816:Csmd1	UTSW	8	16,052,522 (GRCm39)	missense	probably damaging	1.00
R3818:Csmd1	UTSW	8	16,052,522 (GRCm39)	missense	probably damaging	1.00
R3819:Csmd1	UTSW	8	16,052,522 (GRCm39)	missense	probably damaging	1.00
R3850:Csmd1	UTSW	8	16,129,936 (GRCm39)	missense	probably benign	0.00
R3945:Csmd1	UTSW	8	15,960,619 (GRCm39)	splice site	probably null
R3980:Csmd1	UTSW	8	15,956,056 (GRCm39)	nonsense	probably null
R4061:Csmd1	UTSW	8	15,995,158 (GRCm39)	missense	probably benign	0.00
R4086:Csmd1	UTSW	8	16,042,738 (GRCm39)	missense	probably damaging	0.99
R4087:Csmd1	UTSW	8	16,042,738 (GRCm39)	missense	probably damaging	0.99
R4089:Csmd1	UTSW	8	16,042,738 (GRCm39)	missense	probably damaging	0.99
R4183:Csmd1	UTSW	8	15,960,464 (GRCm39)	missense	probably damaging	0.99
R4226:Csmd1	UTSW	8	16,050,490 (GRCm39)	missense	probably damaging	0.99
R4454:Csmd1	UTSW	8	15,995,011 (GRCm39)	missense	probably damaging	0.99
R4533:Csmd1	UTSW	8	15,981,037 (GRCm39)	splice site	probably null
R4544:Csmd1	UTSW	8	16,760,652 (GRCm39)	missense	possibly damaging	0.93
R4547:Csmd1	UTSW	8	16,441,811 (GRCm39)	missense	possibly damaging	0.48
R4612:Csmd1	UTSW	8	15,971,908 (GRCm39)	splice site	probably null
R4620:Csmd1	UTSW	8	16,052,694 (GRCm39)	critical splice acceptor site	probably null
R4627:Csmd1	UTSW	8	16,747,933 (GRCm39)	missense	probably benign	0.00
R4633:Csmd1	UTSW	8	16,052,620 (GRCm39)	missense	probably damaging	0.99
R4646:Csmd1	UTSW	8	15,982,511 (GRCm39)	missense	possibly damaging	0.87
R4648:Csmd1	UTSW	8	16,048,788 (GRCm39)	nonsense	probably null
R4668:Csmd1	UTSW	8	16,073,905 (GRCm39)	missense	possibly damaging	0.50
R4709:Csmd1	UTSW	8	16,760,522 (GRCm39)	critical splice donor site	probably null
R4709:Csmd1	UTSW	8	16,073,905 (GRCm39)	missense	possibly damaging	0.96
R4741:Csmd1	UTSW	8	15,960,447 (GRCm39)	missense	probably damaging	0.99
R4774:Csmd1	UTSW	8	16,059,369 (GRCm39)	missense	probably benign	0.11
R4793:Csmd1	UTSW	8	16,138,277 (GRCm39)	missense	probably damaging	1.00
R4829:Csmd1	UTSW	8	16,177,310 (GRCm39)	missense	probably damaging	1.00
R4888:Csmd1	UTSW	8	15,945,674 (GRCm39)	utr 3 prime	probably benign
R4896:Csmd1	UTSW	8	16,059,439 (GRCm39)	missense	probably benign	0.00
R4932:Csmd1	UTSW	8	16,073,779 (GRCm39)	missense	probably damaging	0.99
R4944:Csmd1	UTSW	8	16,048,772 (GRCm39)	missense	probably damaging	1.00
R4953:Csmd1	UTSW	8	16,249,931 (GRCm39)	missense	probably damaging	0.99
R4996:Csmd1	UTSW	8	15,960,452 (GRCm39)	missense	probably damaging	0.97
R5028:Csmd1	UTSW	8	16,039,090 (GRCm39)	missense	probably damaging	1.00
R5146:Csmd1	UTSW	8	16,246,204 (GRCm39)	missense	probably damaging	1.00
R5272:Csmd1	UTSW	8	16,249,958 (GRCm39)	missense	probably damaging	0.99
R5327:Csmd1	UTSW	8	17,266,728 (GRCm39)	missense	possibly damaging	0.94
R5399:Csmd1	UTSW	8	16,760,613 (GRCm39)	missense	probably damaging	1.00
R5411:Csmd1	UTSW	8	15,960,471 (GRCm39)	missense	probably damaging	1.00
R5462:Csmd1	UTSW	8	16,011,486 (GRCm39)	missense	probably benign	0.12
R5463:Csmd1	UTSW	8	16,034,860 (GRCm39)	missense	probably benign	0.34
R5497:Csmd1	UTSW	8	16,135,195 (GRCm39)	missense	probably benign	0.20
R5536:Csmd1	UTSW	8	16,338,674 (GRCm39)	missense	probably damaging	0.99
R5711:Csmd1	UTSW	8	16,003,703 (GRCm39)	missense	probably damaging	1.00
R5730:Csmd1	UTSW	8	16,235,206 (GRCm39)	nonsense	probably null
R5788:Csmd1	UTSW	8	16,251,980 (GRCm39)	missense	probably damaging	1.00
R5941:Csmd1	UTSW	8	15,982,471 (GRCm39)	missense	probably damaging	0.99
R5960:Csmd1	UTSW	8	16,121,430 (GRCm39)	missense	possibly damaging	0.68
R5961:Csmd1	UTSW	8	16,120,366 (GRCm39)	missense	probably damaging	0.99
R5969:Csmd1	UTSW	8	16,121,367 (GRCm39)	missense	probably benign	0.00
R5998:Csmd1	UTSW	8	15,960,443 (GRCm39)	missense	probably damaging	1.00
R6062:Csmd1	UTSW	8	16,142,319 (GRCm39)	missense	possibly damaging	0.68
R6109:Csmd1	UTSW	8	16,249,874 (GRCm39)	missense	possibly damaging	0.93
R6116:Csmd1	UTSW	8	16,261,864 (GRCm39)	missense	probably damaging	1.00
R6143:Csmd1	UTSW	8	16,138,315 (GRCm39)	missense	probably damaging	1.00
R6155:Csmd1	UTSW	8	15,953,231 (GRCm39)	missense	probably benign	0.01
R6197:Csmd1	UTSW	8	15,976,611 (GRCm39)	missense	probably benign	0.32
R6247:Csmd1	UTSW	8	16,246,249 (GRCm39)	missense	possibly damaging	0.91
R6304:Csmd1	UTSW	8	16,108,688 (GRCm39)	missense	probably damaging	1.00
R6317:Csmd1	UTSW	8	16,760,658 (GRCm39)	missense	possibly damaging	0.89
R6318:Csmd1	UTSW	8	15,953,212 (GRCm39)	missense	probably damaging	1.00
R6338:Csmd1	UTSW	8	15,982,492 (GRCm39)	missense	possibly damaging	0.75
R6369:Csmd1	UTSW	8	17,585,020 (GRCm39)	start gained	probably benign
R6447:Csmd1	UTSW	8	15,960,527 (GRCm39)	missense	probably damaging	1.00
R6454:Csmd1	UTSW	8	15,971,150 (GRCm39)	missense	probably damaging	0.99
R6494:Csmd1	UTSW	8	16,261,709 (GRCm39)	splice site	probably null
R6614:Csmd1	UTSW	8	17,266,803 (GRCm39)	missense	probably damaging	1.00
R6736:Csmd1	UTSW	8	16,052,626 (GRCm39)	missense	probably damaging	0.99
R6769:Csmd1	UTSW	8	16,121,408 (GRCm39)	missense	possibly damaging	0.80
R6771:Csmd1	UTSW	8	16,121,408 (GRCm39)	missense	possibly damaging	0.80
R6804:Csmd1	UTSW	8	16,087,260 (GRCm39)	missense	probably damaging	1.00
R6818:Csmd1	UTSW	8	16,235,341 (GRCm39)	missense	probably damaging	1.00
R6930:Csmd1	UTSW	8	16,142,409 (GRCm39)	missense	probably damaging	0.97
R6969:Csmd1	UTSW	8	17,266,805 (GRCm39)	missense	possibly damaging	0.94
R7112:Csmd1	UTSW	8	16,151,142 (GRCm39)	missense	probably damaging	1.00
R7124:Csmd1	UTSW	8	15,953,202 (GRCm39)	missense	probably damaging	1.00
R7167:Csmd1	UTSW	8	15,976,524 (GRCm39)	missense	probably benign
R7243:Csmd1	UTSW	8	15,965,357 (GRCm39)	missense	probably damaging	1.00
R7260:Csmd1	UTSW	8	16,050,574 (GRCm39)	missense	probably damaging	1.00
R7271:Csmd1	UTSW	8	17,077,295 (GRCm39)	missense	probably damaging	0.99
R7324:Csmd1	UTSW	8	16,108,721 (GRCm39)	missense	probably damaging	1.00
R7325:Csmd1	UTSW	8	16,108,721 (GRCm39)	missense	probably damaging	1.00
R7327:Csmd1	UTSW	8	16,108,721 (GRCm39)	missense	probably damaging	1.00
R7373:Csmd1	UTSW	8	16,042,713 (GRCm39)	missense	probably damaging	1.00
R7406:Csmd1	UTSW	8	16,338,707 (GRCm39)	missense	probably damaging	0.99
R7427:Csmd1	UTSW	8	16,073,864 (GRCm39)	missense	possibly damaging	0.91
R7428:Csmd1	UTSW	8	16,073,864 (GRCm39)	missense	possibly damaging	0.91
R7445:Csmd1	UTSW	8	16,208,268 (GRCm39)	missense	possibly damaging	0.61
R7458:Csmd1	UTSW	8	16,003,738 (GRCm39)	missense	probably damaging	1.00
R7476:Csmd1	UTSW	8	15,945,731 (GRCm39)	missense	probably damaging	1.00
R7527:Csmd1	UTSW	8	16,261,732 (GRCm39)	missense	probably damaging	1.00
R7544:Csmd1	UTSW	8	16,142,310 (GRCm39)	missense	probably damaging	1.00
R7583:Csmd1	UTSW	8	16,048,833 (GRCm39)	missense	probably damaging	0.96
R7603:Csmd1	UTSW	8	16,338,696 (GRCm39)	missense	probably damaging	1.00
R7607:Csmd1	UTSW	8	15,968,331 (GRCm39)	missense	possibly damaging	0.94
R7642:Csmd1	UTSW	8	16,135,192 (GRCm39)	missense	probably damaging	0.99
R7669:Csmd1	UTSW	8	15,967,273 (GRCm39)	missense	probably damaging	1.00
R7720:Csmd1	UTSW	8	15,981,108 (GRCm39)	missense	probably damaging	1.00
R7728:Csmd1	UTSW	8	16,281,285 (GRCm39)	missense	probably damaging	1.00
R7738:Csmd1	UTSW	8	16,151,004 (GRCm39)	missense	probably damaging	1.00
R7745:Csmd1	UTSW	8	15,982,461 (GRCm39)	critical splice donor site	probably null
R7879:Csmd1	UTSW	8	16,441,820 (GRCm39)	missense	probably benign	0.28
R7884:Csmd1	UTSW	8	16,011,418 (GRCm39)	missense	probably damaging	1.00
R7897:Csmd1	UTSW	8	17,584,935 (GRCm39)	missense	possibly damaging	0.96
R8111:Csmd1	UTSW	8	15,967,306 (GRCm39)	missense	probably benign
R8119:Csmd1	UTSW	8	17,077,310 (GRCm39)	missense	probably damaging	0.99
R8134:Csmd1	UTSW	8	15,982,550 (GRCm39)	missense	probably damaging	0.99
R8187:Csmd1	UTSW	8	16,177,188 (GRCm39)	missense	probably damaging	0.99
R8196:Csmd1	UTSW	8	16,059,468 (GRCm39)	missense	probably benign	0.18
R8231:Csmd1	UTSW	8	16,747,939 (GRCm39)	missense	possibly damaging	0.82
R8242:Csmd1	UTSW	8	16,760,670 (GRCm39)	missense	probably benign	0.42
R8274:Csmd1	UTSW	8	15,960,453 (GRCm39)	missense	possibly damaging	0.93
R8286:Csmd1	UTSW	8	16,039,188 (GRCm39)	missense	probably benign	0.18
R8289:Csmd1	UTSW	8	16,108,716 (GRCm39)	missense	probably damaging	0.99
R8314:Csmd1	UTSW	8	16,208,258 (GRCm39)	missense	probably benign
R8323:Csmd1	UTSW	8	17,266,751 (GRCm39)	nonsense	probably null
R8387:Csmd1	UTSW	8	16,050,484 (GRCm39)	missense	possibly damaging	0.94
R8413:Csmd1	UTSW	8	15,950,676 (GRCm39)	missense	probably damaging	0.98
R8672:Csmd1	UTSW	8	15,976,598 (GRCm39)	missense	probably benign	0.01
R8765:Csmd1	UTSW	8	16,760,627 (GRCm39)	nonsense	probably null
R8789:Csmd1	UTSW	8	17,266,722 (GRCm39)	missense	probably damaging	0.99
R8828:Csmd1	UTSW	8	16,048,794 (GRCm39)	missense	probably benign	0.00
R8858:Csmd1	UTSW	8	16,120,318 (GRCm39)	missense	probably benign	0.10
R8878:Csmd1	UTSW	8	15,960,528 (GRCm39)	missense	probably damaging	1.00
R8911:Csmd1	UTSW	8	16,748,019 (GRCm39)	missense	probably damaging	0.99
R8966:Csmd1	UTSW	8	16,250,059 (GRCm39)	missense	probably damaging	1.00
R8978:Csmd1	UTSW	8	15,971,056 (GRCm39)	missense	probably benign	0.37
R8996:Csmd1	UTSW	8	15,971,105 (GRCm39)	missense	possibly damaging	0.54
R9045:Csmd1	UTSW	8	16,284,088 (GRCm39)	missense	probably damaging	0.99
R9084:Csmd1	UTSW	8	16,138,325 (GRCm39)	missense	probably benign
R9124:Csmd1	UTSW	8	16,034,806 (GRCm39)	missense	probably damaging	0.99
R9127:Csmd1	UTSW	8	16,273,286 (GRCm39)	missense	probably benign	0.31
R9146:Csmd1	UTSW	8	16,048,832 (GRCm39)	missense	probably benign	0.00
R9198:Csmd1	UTSW	8	15,962,430 (GRCm39)	missense	probably damaging	1.00
R9285:Csmd1	UTSW	8	15,956,088 (GRCm39)	missense	probably damaging	1.00
R9303:Csmd1	UTSW	8	16,011,532 (GRCm39)	missense	probably benign	0.31
R9305:Csmd1	UTSW	8	16,011,532 (GRCm39)	missense	probably benign	0.31
R9326:Csmd1	UTSW	8	16,049,803 (GRCm39)	missense	probably benign	0.21
R9356:Csmd1	UTSW	8	16,252,069 (GRCm39)	missense	probably damaging	1.00
R9385:Csmd1	UTSW	8	16,034,756 (GRCm39)	missense	probably benign	0.19
R9444:Csmd1	UTSW	8	16,208,250 (GRCm39)	missense	probably benign	0.30
R9476:Csmd1	UTSW	8	15,981,215 (GRCm39)	critical splice acceptor site	probably null
R9506:Csmd1	UTSW	8	16,250,023 (GRCm39)	missense	probably damaging	1.00
R9614:Csmd1	UTSW	8	16,208,239 (GRCm39)	missense	probably benign	0.00
R9668:Csmd1	UTSW	8	16,261,772 (GRCm39)	missense	probably benign	0.00
X0011:Csmd1	UTSW	8	16,246,277 (GRCm39)	missense	probably damaging	1.00
X0021:Csmd1	UTSW	8	16,235,270 (GRCm39)	missense	probably damaging	1.00
X0024:Csmd1	UTSW	8	16,087,232 (GRCm39)	missense	probably damaging	0.99
X0028:Csmd1	UTSW	8	15,965,333 (GRCm39)	missense	possibly damaging	0.79
Z1088:Csmd1	UTSW	8	16,239,992 (GRCm39)	missense	possibly damaging	0.50
Z1088:Csmd1	UTSW	8	16,142,272 (GRCm39)	missense	probably damaging	1.00
Z1088:Csmd1	UTSW	8	15,971,875 (GRCm39)	missense	possibly damaging	0.91
Z1088:Csmd1	UTSW	8	16,396,631 (GRCm39)	missense	probably damaging	0.99
Z1088:Csmd1	UTSW	8	16,250,072 (GRCm39)	missense	probably damaging	0.97
Z1176:Csmd1	UTSW	8	16,087,212 (GRCm39)	missense	probably damaging	1.00
Z1176:Csmd1	UTSW	8	16,048,814 (GRCm39)	missense	probably damaging	1.00
Z1177:Csmd1	UTSW	8	16,250,033 (GRCm39)	missense	probably damaging	1.00
Z1177:Csmd1	UTSW	8	16,034,708 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GTCGTTTAAGCCCAAGTGAGG -3'
(R):5'- CTCGCTCAGAGCATCTTCAG -3'

Sequencing Primer
(F):5'- ACGCGATGGAAGCTCGGTATC -3'
(R):5'- TCAGAGCATCTTCAGCCCCG -3'

Posted On

2018-10-18