Incidental Mutation 'IGL01010:Psg26'
| ID |
53649 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Psg26
|
| Ensembl Gene |
ENSMUSG00000070799 |
| Gene Name |
pregnancy-specific beta-1-glycoprotein 26 |
| Synonyms |
EG574429, cea14 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.052)
|
| Stock # |
IGL01010
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
18208507-18218102 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 18212255 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 367
(S367G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000092392
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094798]
|
| AlphaFold |
Q4KL65 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000094798
AA Change: S367G
PolyPhen 2
Score 0.829 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000092392
Gene: ENSMUSG00000070799
AA Change: S367G
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
40 |
141 |
4.93e-3 |
SMART |
|
IG
|
160 |
261 |
2.39e-1 |
SMART |
|
IG
|
280 |
379 |
6.07e-3 |
SMART |
|
IGc2
|
397 |
461 |
5.48e-10 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 26 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700030K09Rik |
C |
A |
8: 73,199,059 (GRCm39) |
S155R |
probably damaging |
Het |
| Acss3 |
G |
T |
10: 106,859,710 (GRCm39) |
|
probably benign |
Het |
| Ano4 |
G |
A |
10: 88,796,462 (GRCm39) |
T680I |
probably benign |
Het |
| Drosha |
C |
T |
15: 12,827,375 (GRCm39) |
|
probably benign |
Het |
| Ehd3 |
A |
G |
17: 74,134,484 (GRCm39) |
D281G |
probably damaging |
Het |
| Exoc5 |
A |
G |
14: 49,275,212 (GRCm39) |
L196P |
probably damaging |
Het |
| Gal3st1 |
T |
C |
11: 3,946,914 (GRCm39) |
|
probably benign |
Het |
| Gart |
G |
A |
16: 91,439,980 (GRCm39) |
R4* |
probably null |
Het |
| Gm21738 |
T |
A |
14: 19,417,361 (GRCm38) |
T56S |
probably benign |
Het |
| Gm3573 |
T |
A |
14: 42,009,523 (GRCm39) |
I141L |
probably benign |
Het |
| Gpr6 |
A |
G |
10: 40,947,147 (GRCm39) |
M145T |
probably benign |
Het |
| Kcns3 |
T |
C |
12: 11,142,427 (GRCm39) |
M91V |
probably benign |
Het |
| Mtarc2 |
T |
G |
1: 184,551,513 (GRCm39) |
I308L |
probably benign |
Het |
| Mto1 |
A |
G |
9: 78,368,925 (GRCm39) |
K529R |
probably benign |
Het |
| Naip2 |
A |
T |
13: 100,291,446 (GRCm39) |
V1164D |
probably damaging |
Het |
| Or2ag13 |
T |
C |
7: 106,473,460 (GRCm39) |
|
probably benign |
Het |
| Or8k21 |
A |
T |
2: 86,145,288 (GRCm39) |
I114N |
probably damaging |
Het |
| Plekha1 |
T |
C |
7: 130,503,984 (GRCm39) |
|
probably benign |
Het |
| Rps6kb1 |
T |
C |
11: 86,393,592 (GRCm39) |
M513V |
probably benign |
Het |
| Slitrk3 |
C |
T |
3: 72,956,606 (GRCm39) |
G722D |
probably benign |
Het |
| Stag1 |
A |
G |
9: 100,827,986 (GRCm39) |
E1005G |
probably benign |
Het |
| Tgfbr2 |
A |
T |
9: 115,959,048 (GRCm39) |
L122Q |
possibly damaging |
Het |
| Traf2 |
G |
A |
2: 25,410,450 (GRCm39) |
R400* |
probably null |
Het |
| Trim33 |
C |
T |
3: 103,254,031 (GRCm39) |
Q153* |
probably null |
Het |
| Zmynd15 |
T |
C |
11: 70,356,742 (GRCm39) |
Y551H |
probably damaging |
Het |
| Znrd2 |
A |
G |
19: 5,781,293 (GRCm39) |
S78P |
probably damaging |
Het |
|
| Other mutations in Psg26 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01383:Psg26
|
APN |
7 |
18,214,179 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01453:Psg26
|
APN |
7 |
18,213,999 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01603:Psg26
|
APN |
7 |
18,209,028 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02201:Psg26
|
APN |
7 |
18,214,071 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02468:Psg26
|
APN |
7 |
18,212,387 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02648:Psg26
|
APN |
7 |
18,216,691 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02812:Psg26
|
APN |
7 |
18,209,080 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0226:Psg26
|
UTSW |
7 |
18,217,883 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0352:Psg26
|
UTSW |
7 |
18,209,181 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0369:Psg26
|
UTSW |
7 |
18,216,481 (GRCm39) |
nonsense |
probably null |
|
|
R0718:Psg26
|
UTSW |
7 |
18,212,212 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0718:Psg26
|
UTSW |
7 |
18,209,160 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1710:Psg26
|
UTSW |
7 |
18,213,966 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1899:Psg26
|
UTSW |
7 |
18,212,350 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1958:Psg26
|
UTSW |
7 |
18,212,264 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2102:Psg26
|
UTSW |
7 |
18,209,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3766:Psg26
|
UTSW |
7 |
18,208,996 (GRCm39) |
missense |
probably benign |
|
|
R4544:Psg26
|
UTSW |
7 |
18,212,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4977:Psg26
|
UTSW |
7 |
18,209,235 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5000:Psg26
|
UTSW |
7 |
18,214,057 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5376:Psg26
|
UTSW |
7 |
18,214,030 (GRCm39) |
missense |
probably benign |
|
|
R5416:Psg26
|
UTSW |
7 |
18,216,525 (GRCm39) |
missense |
probably benign |
|
|
R5435:Psg26
|
UTSW |
7 |
18,212,398 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6000:Psg26
|
UTSW |
7 |
18,216,617 (GRCm39) |
nonsense |
probably null |
|
|
R6285:Psg26
|
UTSW |
7 |
18,216,753 (GRCm39) |
missense |
probably benign |
|
|
R7062:Psg26
|
UTSW |
7 |
18,216,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7083:Psg26
|
UTSW |
7 |
18,213,934 (GRCm39) |
nonsense |
probably null |
|
|
R7513:Psg26
|
UTSW |
7 |
18,209,225 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7817:Psg26
|
UTSW |
7 |
18,216,572 (GRCm39) |
missense |
not run |
|
|
R7857:Psg26
|
UTSW |
7 |
18,212,215 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7905:Psg26
|
UTSW |
7 |
18,209,242 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8047:Psg26
|
UTSW |
7 |
18,212,474 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8789:Psg26
|
UTSW |
7 |
18,216,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8877:Psg26
|
UTSW |
7 |
18,217,865 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9012:Psg26
|
UTSW |
7 |
18,216,596 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9203:Psg26
|
UTSW |
7 |
18,212,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9327:Psg26
|
UTSW |
7 |
18,216,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9547:Psg26
|
UTSW |
7 |
18,214,087 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Psg26
|
UTSW |
7 |
18,214,216 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Posted On |
2013-06-28 |
Incidental Mutation