Mutagenetix > Incidental Mutation

Incidental Mutation 'R6919:Pcnt'

539511

Institutional Source

Beutler Lab

Gene Symbol

Pcnt

Ensembl Gene

ENSMUSG00000001151

Gene Name

pericentrin (kendrin)

Synonyms

m275Asp, m239Asp, Pcnt2

MMRRC Submission

045039-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R6919 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

76187097-76278620 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 76221632 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 1998 (V1998A)

Ref Sequence

ENSEMBL: ENSMUSP00000001179 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000001179] [ENSMUST00000217838]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000001179
AA Change: V1998A

PolyPhen 2 Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000001179
Gene: ENSMUSG00000001151
AA Change: V1998A

Domain	Start	End	E-Value	Type
internal_repeat_1	7	78	2.47e-5	PROSPERO
low complexity region	104	114	N/A	INTRINSIC
coiled coil region	131	229	N/A	INTRINSIC
internal_repeat_3	241	259	6.69e-5	PROSPERO
low complexity region	313	325	N/A	INTRINSIC
internal_repeat_3	391	409	6.69e-5	PROSPERO
low complexity region	456	467	N/A	INTRINSIC
coiled coil region	468	520	N/A	INTRINSIC
coiled coil region	554	581	N/A	INTRINSIC
low complexity region	652	666	N/A	INTRINSIC
coiled coil region	727	787	N/A	INTRINSIC
coiled coil region	871	916	N/A	INTRINSIC
low complexity region	931	942	N/A	INTRINSIC
low complexity region	969	985	N/A	INTRINSIC
coiled coil region	1055	1383	N/A	INTRINSIC
coiled coil region	1429	1481	N/A	INTRINSIC
coiled coil region	1529	1567	N/A	INTRINSIC
low complexity region	1614	1624	N/A	INTRINSIC
internal_repeat_2	1916	1964	2.47e-5	PROSPERO
coiled coil region	2158	2178	N/A	INTRINSIC
coiled coil region	2211	2279	N/A	INTRINSIC
coiled coil region	2300	2421	N/A	INTRINSIC
coiled coil region	2447	2526	N/A	INTRINSIC
Pfam:PACT_coil_coil	2718	2797	5.8e-29	PFAM
internal_repeat_1	2820	2885	2.47e-5	PROSPERO
internal_repeat_2	2844	2891	2.47e-5	PROSPERO

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000190491

Predicted Effect

probably benign
Transcript: ENSMUST00000217838
AA Change: V1998A

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000220395

Meta Mutation Damage Score

0.0846

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.3%
20x: 97.8%

Validation Efficiency

99% (84/85)

MGI Phenotype

PHENOTYPE: Mice homozygous for a gene trapped allele display mitotic spindle misorientation, microcephaly, craniofacial developmental anomalies, such as cleft palate and eye defects, variable structural kidney and cardiovascular defects, and altered hemodynamics leading to heart failure and prenatal lethality. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 83 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700086D15Rik	A	G	11: 65,043,356 (GRCm39)		probably benign	Het
6430548M08Rik	T	C	8: 120,872,221 (GRCm39)	S50P	probably damaging	Het
Aacs	A	G	5: 125,583,227 (GRCm39)	D261G	probably benign	Het
Abcc4	T	A	14: 118,832,306 (GRCm39)	T775S	probably benign	Het
Acsl6	A	G	11: 54,232,582 (GRCm39)		probably null	Het
Agbl5	T	A	5: 31,062,061 (GRCm39)	F196I	probably benign	Het
Ahnak2	T	C	12: 112,741,118 (GRCm39)	T985A	possibly damaging	Het
Ak1	A	T	2: 32,521,134 (GRCm39)	D101V	possibly damaging	Het
Alx1	A	G	10: 102,861,061 (GRCm39)	Y156H	probably damaging	Het
Angptl7	T	A	4: 148,584,488 (GRCm39)	S87C	probably benign	Het
Ankrd36	A	G	11: 5,579,299 (GRCm39)	T188A	probably benign	Het
Arhgap11a	A	C	2: 113,670,054 (GRCm39)	S356R	possibly damaging	Het
Ascc3	G	T	10: 50,521,849 (GRCm39)	E455*	probably null	Het
Atp6v0a2	G	A	5: 124,789,225 (GRCm39)		probably null	Het
B3gnt7	T	C	1: 86,233,416 (GRCm39)	W104R	probably damaging	Het
Bbs9	G	A	9: 22,723,840 (GRCm39)		probably null	Het
Cc2d2a	T	A	5: 43,860,557 (GRCm39)	D544E	probably benign	Het
Cic	C	T	7: 24,971,202 (GRCm39)	T311I	probably benign	Het
Cngb1	T	A	8: 95,975,003 (GRCm39)	R1157W	probably null	Het
Cntln	A	G	4: 85,033,605 (GRCm39)	H1310R	probably benign	Het
Cntnap5c	A	T	17: 58,600,948 (GRCm39)	I764F	probably benign	Het
Col26a1	T	C	5: 136,773,088 (GRCm39)	Q362R	possibly damaging	Het
Cyp2c29	G	A	19: 39,279,585 (GRCm39)	R100K	probably benign	Het
D17H6S53E	C	G	17: 35,346,222 (GRCm39)	D44E	probably damaging	Het
Dap3	A	G	3: 88,838,296 (GRCm39)	V65A	probably damaging	Het
Dna2	A	T	10: 62,792,782 (GRCm39)	I266F	probably damaging	Het
Dnah14	G	A	1: 181,412,631 (GRCm39)	G57E	probably benign	Het
Dock9	A	T	14: 121,880,564 (GRCm39)	V333E	probably benign	Het
Dpm1	A	G	2: 168,072,195 (GRCm39)	Y27H	probably damaging	Het
Dsp	A	T	13: 38,351,631 (GRCm39)	Y150F	possibly damaging	Het
Emilin3	A	T	2: 160,750,018 (GRCm39)	I577N	probably damaging	Het
Erap1	A	G	13: 74,819,552 (GRCm39)	T189A	probably benign	Het
Fat2	A	G	11: 55,173,597 (GRCm39)	I2372T	possibly damaging	Het
Fbn2	A	T	18: 58,257,259 (GRCm39)		probably null	Het
Gnl1	A	T	17: 36,298,425 (GRCm39)	R390*	probably null	Het
Hivep1	A	G	13: 42,336,928 (GRCm39)	I2336V	probably benign	Het
Il17rb	C	G	14: 29,726,228 (GRCm39)		probably null	Het
Itga9	T	C	9: 118,716,883 (GRCm39)	W396R	probably damaging	Het
Katnal2	A	G	18: 77,098,734 (GRCm39)	V152A	probably benign	Het
Kcnk3	A	G	5: 30,779,744 (GRCm39)	T265A	probably benign	Het
Klhl1	T	C	14: 96,374,030 (GRCm39)	Y672C	probably benign	Het
Leng8	C	A	7: 4,146,625 (GRCm39)	N412K	possibly damaging	Het
Lrrc9	T	A	12: 72,553,167 (GRCm39)	F1356L	probably benign	Het
Map7	A	G	10: 20,046,828 (GRCm39)		probably benign	Het
Mei1	T	C	15: 81,966,131 (GRCm39)	F251S	probably damaging	Het
Mia2	A	G	12: 59,176,681 (GRCm39)	E9G	possibly damaging	Het
Ms4a13	C	A	19: 11,149,249 (GRCm39)	W182C	probably benign	Het
Muc16	C	T	9: 18,571,595 (GRCm39)	R308K	unknown	Het
Or4c103	G	A	2: 88,514,028 (GRCm39)	T16I	possibly damaging	Het
Or8g22	A	G	9: 38,958,827 (GRCm39)		probably benign	Het
Pgm2	A	T	5: 64,254,368 (GRCm39)	N51I	probably benign	Het
Piezo1	T	A	8: 123,217,020 (GRCm39)	H1333L	probably damaging	Het
Prg2	G	A	2: 84,813,600 (GRCm39)	V199M	probably damaging	Het
Prss51	T	C	14: 64,334,937 (GRCm39)	V182A	probably damaging	Het
Psmb9	A	T	17: 34,402,199 (GRCm39)	Y132*	probably null	Het
Ralyl	T	C	3: 13,842,091 (GRCm39)	Y76H	probably damaging	Het
Rnaset2a	A	T	17: 8,349,114 (GRCm39)	D174E	probably benign	Het
Rnft1	G	A	11: 86,386,156 (GRCm39)		probably null	Het
Robo2	T	C	16: 73,758,755 (GRCm39)	Y676C	probably damaging	Het
Samd9l	T	G	6: 3,376,313 (GRCm39)	Y316S	possibly damaging	Het
Siah3	T	A	14: 75,693,578 (GRCm39)	F28Y	possibly damaging	Het
Slc28a3	C	T	13: 58,721,257 (GRCm39)		probably null	Het
Slc8a1	A	G	17: 81,696,301 (GRCm39)	F911S	probably damaging	Het
Spata31e2	T	C	1: 26,722,015 (GRCm39)	Y1055C	probably benign	Het
Speg	T	A	1: 75,364,552 (GRCm39)	L156*	probably null	Het
Spopl	T	G	2: 23,407,873 (GRCm39)	M269L	probably benign	Het
Tacr1	C	T	6: 82,534,054 (GRCm39)	T360I	probably benign	Het
Tasor	T	A	14: 27,171,758 (GRCm39)	L397*	probably null	Het
Tmem262	A	G	19: 6,130,767 (GRCm39)	E95G	probably benign	Het
Tmem68	G	T	4: 3,569,669 (GRCm39)	T7N	possibly damaging	Het
Top3a	T	A	11: 60,640,319 (GRCm39)	I460F	probably damaging	Het
Trafd1	G	A	5: 121,522,137 (GRCm39)	R5*	probably null	Het
Trim16	T	A	11: 62,731,695 (GRCm39)	V435D	possibly damaging	Het
Tspan17	A	G	13: 54,943,846 (GRCm39)	D236G	probably damaging	Het
Tssk2	A	T	16: 17,717,565 (GRCm39)	M323L	probably benign	Het
Ubqln5	A	G	7: 103,778,215 (GRCm39)	V203A	probably benign	Het
Utrn	A	T	10: 12,569,214 (GRCm39)	L1134*	probably null	Het
Vmn1r37	C	T	6: 66,708,704 (GRCm39)	S73F	possibly damaging	Het
Vps13c	A	G	9: 67,834,734 (GRCm39)	K1688E	probably damaging	Het
Zbtb39	A	G	10: 127,577,711 (GRCm39)	D95G	probably damaging	Het
Zfhx3	T	A	8: 109,527,160 (GRCm39)	I1019N	probably damaging	Het
Zfp207	C	T	11: 80,286,329 (GRCm39)		probably benign	Het
Zmiz1	C	T	14: 25,644,062 (GRCm39)	T169M	probably damaging	Het

Other mutations in Pcnt

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01075:Pcnt	APN	10	76,258,738 (GRCm39)	nonsense	probably null
IGL01307:Pcnt	APN	10	76,247,422 (GRCm39)	missense	probably damaging	1.00
IGL01549:Pcnt	APN	10	76,203,320 (GRCm39)	splice site	probably null
IGL01576:Pcnt	APN	10	76,204,656 (GRCm39)	missense	probably damaging	0.99
IGL01611:Pcnt	APN	10	76,272,258 (GRCm39)	critical splice donor site	probably null
IGL01630:Pcnt	APN	10	76,256,080 (GRCm39)	missense	probably damaging	0.99
IGL01647:Pcnt	APN	10	76,205,835 (GRCm39)	nonsense	probably null
IGL01689:Pcnt	APN	10	76,247,487 (GRCm39)	missense	probably damaging	1.00
IGL01690:Pcnt	APN	10	76,228,609 (GRCm39)	missense	probably damaging	1.00
IGL01723:Pcnt	APN	10	76,254,333 (GRCm39)	missense	possibly damaging	0.63
IGL01920:Pcnt	APN	10	76,240,362 (GRCm39)	missense	probably damaging	1.00
IGL01958:Pcnt	APN	10	76,269,513 (GRCm39)	missense	probably damaging	0.96
IGL02210:Pcnt	APN	10	76,225,053 (GRCm39)	missense	possibly damaging	0.95
IGL02225:Pcnt	APN	10	76,225,308 (GRCm39)	missense	probably benign	0.00
IGL02228:Pcnt	APN	10	76,225,308 (GRCm39)	missense	probably benign	0.00
IGL02237:Pcnt	APN	10	76,188,818 (GRCm39)	missense	probably damaging	1.00
IGL02279:Pcnt	APN	10	76,239,599 (GRCm39)	missense	probably damaging	1.00
IGL02303:Pcnt	APN	10	76,278,393 (GRCm39)	splice site	probably benign
IGL02355:Pcnt	APN	10	76,210,996 (GRCm39)	nonsense	probably null
IGL02362:Pcnt	APN	10	76,210,996 (GRCm39)	nonsense	probably null
IGL02428:Pcnt	APN	10	76,265,090 (GRCm39)	missense	probably damaging	0.99
IGL02536:Pcnt	APN	10	76,216,063 (GRCm39)	missense	possibly damaging	0.68
IGL02715:Pcnt	APN	10	76,204,556 (GRCm39)	splice site	probably benign
IGL02800:Pcnt	APN	10	76,248,417 (GRCm39)	nonsense	probably null
IGL03395:Pcnt	APN	10	76,272,325 (GRCm39)	missense	possibly damaging	0.95
IGL02799:Pcnt	UTSW	10	76,248,417 (GRCm39)	nonsense	probably null
PIT4520001:Pcnt	UTSW	10	76,256,069 (GRCm39)	missense	probably damaging	0.99
R0049:Pcnt	UTSW	10	76,205,655 (GRCm39)	unclassified	probably benign
R0049:Pcnt	UTSW	10	76,205,655 (GRCm39)	unclassified	probably benign
R0109:Pcnt	UTSW	10	76,225,030 (GRCm39)	missense	probably benign	0.00
R0117:Pcnt	UTSW	10	76,244,561 (GRCm39)	nonsense	probably null
R0254:Pcnt	UTSW	10	76,228,414 (GRCm39)	missense	probably benign	0.10
R0392:Pcnt	UTSW	10	76,220,660 (GRCm39)	missense	probably benign
R0511:Pcnt	UTSW	10	76,240,429 (GRCm39)	missense	possibly damaging	0.66
R0570:Pcnt	UTSW	10	76,247,941 (GRCm39)	missense	probably damaging	1.00
R0614:Pcnt	UTSW	10	76,256,150 (GRCm39)	missense	probably damaging	1.00
R0635:Pcnt	UTSW	10	76,240,419 (GRCm39)	missense	probably damaging	1.00
R0707:Pcnt	UTSW	10	76,256,375 (GRCm39)	missense	probably damaging	1.00
R0749:Pcnt	UTSW	10	76,217,198 (GRCm39)	missense	probably damaging	1.00
R0969:Pcnt	UTSW	10	76,263,785 (GRCm39)	missense	probably damaging	1.00
R1172:Pcnt	UTSW	10	76,228,878 (GRCm39)	splice site	probably null
R1174:Pcnt	UTSW	10	76,228,878 (GRCm39)	splice site	probably null
R1175:Pcnt	UTSW	10	76,228,878 (GRCm39)	splice site	probably null
R1512:Pcnt	UTSW	10	76,240,496 (GRCm39)	splice site	probably null
R1542:Pcnt	UTSW	10	76,237,220 (GRCm39)	missense	probably benign	0.02
R1542:Pcnt	UTSW	10	76,225,221 (GRCm39)	missense	probably benign	0.08
R1558:Pcnt	UTSW	10	76,258,756 (GRCm39)	missense	possibly damaging	0.53
R1562:Pcnt	UTSW	10	76,203,164 (GRCm39)	missense	probably benign	0.02
R1762:Pcnt	UTSW	10	76,190,971 (GRCm39)	critical splice acceptor site	probably null
R1779:Pcnt	UTSW	10	76,244,630 (GRCm39)	missense	probably damaging	0.99
R1869:Pcnt	UTSW	10	76,215,740 (GRCm39)	missense	probably null	0.94
R1911:Pcnt	UTSW	10	76,204,650 (GRCm39)	missense	possibly damaging	0.94
R1985:Pcnt	UTSW	10	76,216,171 (GRCm39)	missense	possibly damaging	0.95
R1995:Pcnt	UTSW	10	76,228,633 (GRCm39)	nonsense	probably null
R2073:Pcnt	UTSW	10	76,216,214 (GRCm39)	missense	possibly damaging	0.92
R2111:Pcnt	UTSW	10	76,256,360 (GRCm39)	missense	probably damaging	0.99
R2112:Pcnt	UTSW	10	76,256,360 (GRCm39)	missense	probably damaging	0.99
R2309:Pcnt	UTSW	10	76,278,460 (GRCm39)	start gained	probably benign
R2902:Pcnt	UTSW	10	76,211,064 (GRCm39)	missense	probably damaging	0.98
R3623:Pcnt	UTSW	10	76,269,584 (GRCm39)	missense	probably benign	0.23
R4088:Pcnt	UTSW	10	76,263,848 (GRCm39)	missense	probably damaging	1.00
R4300:Pcnt	UTSW	10	76,203,225 (GRCm39)	missense	probably benign	0.40
R4402:Pcnt	UTSW	10	76,228,227 (GRCm39)	missense	probably benign	0.00
R4407:Pcnt	UTSW	10	76,210,704 (GRCm39)	missense	possibly damaging	0.90
R4483:Pcnt	UTSW	10	76,237,317 (GRCm39)	missense	probably damaging	1.00
R4647:Pcnt	UTSW	10	76,190,047 (GRCm39)	missense	probably benign	0.01
R4734:Pcnt	UTSW	10	76,273,040 (GRCm39)	missense	probably benign	0.25
R4747:Pcnt	UTSW	10	76,272,299 (GRCm39)	missense	possibly damaging	0.91
R4782:Pcnt	UTSW	10	76,245,411 (GRCm39)	missense	possibly damaging	0.62
R4795:Pcnt	UTSW	10	76,205,858 (GRCm39)	missense	probably benign	0.21
R4831:Pcnt	UTSW	10	76,248,335 (GRCm39)	missense	probably damaging	0.96
R4873:Pcnt	UTSW	10	76,205,688 (GRCm39)	missense	probably benign	0.03
R4875:Pcnt	UTSW	10	76,205,688 (GRCm39)	missense	probably benign	0.03
R4946:Pcnt	UTSW	10	76,192,019 (GRCm39)	missense	probably damaging	1.00
R5032:Pcnt	UTSW	10	76,190,911 (GRCm39)	missense	probably benign	0.00
R5033:Pcnt	UTSW	10	76,235,779 (GRCm39)	missense	possibly damaging	0.95
R5106:Pcnt	UTSW	10	76,237,278 (GRCm39)	missense	probably damaging	1.00
R5118:Pcnt	UTSW	10	76,248,002 (GRCm39)	missense	probably damaging	0.98
R5167:Pcnt	UTSW	10	76,256,258 (GRCm39)	missense	probably damaging	0.97
R5199:Pcnt	UTSW	10	76,254,378 (GRCm39)	missense	probably benign	0.09
R5223:Pcnt	UTSW	10	76,216,106 (GRCm39)	missense	probably damaging	0.99
R5241:Pcnt	UTSW	10	76,269,451 (GRCm39)	missense	probably benign	0.26
R5308:Pcnt	UTSW	10	76,192,159 (GRCm39)	nonsense	probably null
R5328:Pcnt	UTSW	10	76,247,553 (GRCm39)	missense	probably damaging	1.00
R5454:Pcnt	UTSW	10	76,225,381 (GRCm39)	splice site	probably null
R5543:Pcnt	UTSW	10	76,247,886 (GRCm39)	missense	probably benign	0.01
R5588:Pcnt	UTSW	10	76,278,445 (GRCm39)	missense	possibly damaging	0.74
R5647:Pcnt	UTSW	10	76,221,675 (GRCm39)	missense	probably benign	0.17
R5668:Pcnt	UTSW	10	76,245,334 (GRCm39)	missense	probably benign	0.16
R5712:Pcnt	UTSW	10	76,265,105 (GRCm39)	missense	probably damaging	0.96
R5714:Pcnt	UTSW	10	76,256,325 (GRCm39)	missense	probably damaging	1.00
R5797:Pcnt	UTSW	10	76,228,590 (GRCm39)	missense	probably benign	0.00
R5946:Pcnt	UTSW	10	76,217,897 (GRCm39)	missense	possibly damaging	0.91
R5955:Pcnt	UTSW	10	76,247,456 (GRCm39)	missense	possibly damaging	0.45
R6024:Pcnt	UTSW	10	76,255,871 (GRCm39)	missense	possibly damaging	0.87
R6267:Pcnt	UTSW	10	76,221,632 (GRCm39)	missense	probably benign	0.02
R6485:Pcnt	UTSW	10	76,225,164 (GRCm39)	nonsense	probably null
R6605:Pcnt	UTSW	10	76,265,032 (GRCm39)	critical splice donor site	probably null
R6877:Pcnt	UTSW	10	76,269,851 (GRCm39)	missense	possibly damaging	0.94
R6882:Pcnt	UTSW	10	76,263,662 (GRCm39)	missense	probably benign	0.00
R7025:Pcnt	UTSW	10	76,239,669 (GRCm39)	missense	probably damaging	1.00
R7098:Pcnt	UTSW	10	76,220,673 (GRCm39)	missense	probably benign
R7109:Pcnt	UTSW	10	76,205,738 (GRCm39)	missense	probably damaging	1.00
R7121:Pcnt	UTSW	10	76,263,761 (GRCm39)	missense	possibly damaging	0.73
R7143:Pcnt	UTSW	10	76,224,894 (GRCm39)	missense	possibly damaging	0.47
R7152:Pcnt	UTSW	10	76,247,194 (GRCm39)	splice site	probably null
R7213:Pcnt	UTSW	10	76,244,738 (GRCm39)	missense	probably damaging	1.00
R7368:Pcnt	UTSW	10	76,235,835 (GRCm39)	missense	probably benign
R7453:Pcnt	UTSW	10	76,225,284 (GRCm39)	missense	probably benign
R7486:Pcnt	UTSW	10	76,254,271 (GRCm39)	missense	probably benign
R7486:Pcnt	UTSW	10	76,254,270 (GRCm39)	missense	probably benign	0.03
R7538:Pcnt	UTSW	10	76,235,773 (GRCm39)	missense	probably benign
R7575:Pcnt	UTSW	10	76,225,086 (GRCm39)	missense	probably benign	0.32
R7662:Pcnt	UTSW	10	76,223,356 (GRCm39)	missense	probably benign	0.27
R7685:Pcnt	UTSW	10	76,258,642 (GRCm39)	missense	probably benign	0.14
R7764:Pcnt	UTSW	10	76,190,082 (GRCm39)	missense	probably benign	0.33
R7802:Pcnt	UTSW	10	76,211,137 (GRCm39)	splice site	probably null
R8432:Pcnt	UTSW	10	76,256,039 (GRCm39)	missense	probably damaging	1.00
R8439:Pcnt	UTSW	10	76,256,039 (GRCm39)	missense	probably damaging	1.00
R8493:Pcnt	UTSW	10	76,239,457 (GRCm39)	critical splice donor site	probably null
R8530:Pcnt	UTSW	10	76,256,039 (GRCm39)	missense	probably damaging	1.00
R8535:Pcnt	UTSW	10	76,256,039 (GRCm39)	missense	probably damaging	1.00
R8830:Pcnt	UTSW	10	76,218,008 (GRCm39)	missense	probably benign	0.03
R8878:Pcnt	UTSW	10	76,244,675 (GRCm39)	missense	probably damaging	1.00
R8911:Pcnt	UTSW	10	76,223,359 (GRCm39)	missense	probably damaging	0.98
R8988:Pcnt	UTSW	10	76,245,407 (GRCm39)	nonsense	probably null
R9084:Pcnt	UTSW	10	76,235,826 (GRCm39)	missense	probably benign	0.09
R9169:Pcnt	UTSW	10	76,221,572 (GRCm39)	missense	possibly damaging	0.95
R9372:Pcnt	UTSW	10	76,258,960 (GRCm39)	missense	probably damaging	1.00
R9411:Pcnt	UTSW	10	76,258,896 (GRCm39)	missense	probably damaging	0.96
R9448:Pcnt	UTSW	10	76,256,360 (GRCm39)	missense	probably damaging	0.99
R9459:Pcnt	UTSW	10	76,228,572 (GRCm39)	missense	probably damaging	1.00
R9479:Pcnt	UTSW	10	76,217,963 (GRCm39)	missense	probably benign	0.00
R9503:Pcnt	UTSW	10	76,263,882 (GRCm39)	missense	possibly damaging	0.59
R9561:Pcnt	UTSW	10	76,217,128 (GRCm39)	nonsense	probably null
R9618:Pcnt	UTSW	10	76,188,794 (GRCm39)	missense	probably damaging	1.00
R9648:Pcnt	UTSW	10	76,190,089 (GRCm39)	missense	probably benign	0.32
R9733:Pcnt	UTSW	10	76,237,314 (GRCm39)	missense	probably benign	0.01
Z1176:Pcnt	UTSW	10	76,217,991 (GRCm39)	nonsense	probably null
Z1177:Pcnt	UTSW	10	76,235,802 (GRCm39)	missense	probably benign	0.00

Predicted Primers

PCR Primer
(F):5'- CTCCTATACTGTGATGGCCCAG -3'
(R):5'- TGGAAATTGGTGACACCTTTACC -3'

Sequencing Primer
(F):5'- TGAGTGTAGCCCACCAATG -3'
(R):5'- ACCTGGTGCTAATCGGTGC -3'

Posted On

2018-11-06