Incidental Mutation 'IGL01010:Gm3573'
ID53954
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm3573
Ensembl Gene ENSMUSG00000091792
Gene Namepredicted gene 3573
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL01010
Quality Score
Status
Chromosome14
Chromosomal Location42185391-42190791 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 42187566 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Leucine at position 141 (I141L)
Ref Sequence ENSEMBL: ENSMUSP00000127488 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000168673]
Predicted Effect probably benign
Transcript: ENSMUST00000168673
AA Change: I141L

PolyPhen 2 Score 0.083 (Sensitivity: 0.93; Specificity: 0.85)
SMART Domains Protein: ENSMUSP00000127488
Gene: ENSMUSG00000091792
AA Change: I141L

DomainStartEndE-ValueType
Pfam:Takusan 10 88 1.4e-20 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700030K09Rik C A 8: 72,445,215 S155R probably damaging Het
Acss3 G T 10: 107,023,849 probably benign Het
Ano4 G A 10: 88,960,600 T680I probably benign Het
Drosha C T 15: 12,827,289 probably benign Het
Ehd3 A G 17: 73,827,489 D281G probably damaging Het
Exoc5 A G 14: 49,037,755 L196P probably damaging Het
Gal3st1 T C 11: 3,996,914 probably benign Het
Gart G A 16: 91,643,092 R4* probably null Het
Gm21738 T A 14: 19,417,361 T56S probably benign Het
Gpr6 A G 10: 41,071,151 M145T probably benign Het
Kcns3 T C 12: 11,092,426 M91V probably benign Het
Marc2 T G 1: 184,819,316 I308L probably benign Het
Mto1 A G 9: 78,461,643 K529R probably benign Het
Naip2 A T 13: 100,154,938 V1164D probably damaging Het
Olfr1053 A T 2: 86,314,944 I114N probably damaging Het
Olfr695 T C 7: 106,874,253 probably benign Het
Plekha1 T C 7: 130,902,254 probably benign Het
Psg26 T C 7: 18,478,330 S367G possibly damaging Het
Rps6kb1 T C 11: 86,502,766 M513V probably benign Het
Slitrk3 C T 3: 73,049,273 G722D probably benign Het
Sssca1 A G 19: 5,731,265 S78P probably damaging Het
Stag1 A G 9: 100,945,933 E1005G probably benign Het
Tgfbr2 A T 9: 116,129,980 L122Q possibly damaging Het
Traf2 G A 2: 25,520,438 R400* probably null Het
Trim33 C T 3: 103,346,715 Q153* probably null Het
Zmynd15 T C 11: 70,465,916 Y551H probably damaging Het
Other mutations in Gm3573
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02548:Gm3573 APN 14 42187495 critical splice donor site probably null
R6774:Gm3573 UTSW 14 42187515 missense possibly damaging 0.86
R6827:Gm3573 UTSW 14 42188472 missense probably benign 0.00
Posted On2013-06-28