Mutagenetix > Incidental Mutation

Incidental Mutation 'R6945:Fsip2'

540825

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

045059-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.108) question?

Stock #

R6945 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

82773978-82839281 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 82823184 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Leucine at position 6306 (I6306L)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000132967

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000143764
AA Change: I6306L

PolyPhen 2 Score 0.163 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: I6306L

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Meta Mutation Damage Score

0.0824

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.3%
20x: 97.5%

Validation Efficiency

96% (51/53)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 54 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc5	T	A	16: 20,218,759 (GRCm39)	T208S	probably benign	Het
Acaa2	A	G	18: 74,926,380 (GRCm39)	E112G	probably benign	Het
Adgrb1	A	G	15: 74,421,873 (GRCm39)	N881S	probably damaging	Het
Adgre1	A	G	17: 57,717,844 (GRCm39)	E314G	probably benign	Het
Adgre1	A	G	17: 57,727,399 (GRCm39)	E443G	probably benign	Het
Akp3	A	G	1: 87,053,353 (GRCm39)	Y102C	probably damaging	Het
Birc6	A	G	17: 74,886,526 (GRCm39)	N618S	probably benign	Het
Bpifc	A	G	10: 85,815,078 (GRCm39)	V296A	probably benign	Het
Cacna2d3	G	A	14: 28,691,275 (GRCm39)		probably benign	Het
Cacnb4	T	C	2: 52,364,966 (GRCm39)	N99S	probably damaging	Het
Cd38	A	G	5: 44,065,348 (GRCm39)	Y283C	probably damaging	Het
Celf4	T	A	18: 25,629,293 (GRCm39)	Q411L	probably damaging	Het
Cemip	A	T	7: 83,647,755 (GRCm39)	H108Q	probably damaging	Het
Col23a1	A	G	11: 51,452,720 (GRCm39)	E225G	unknown	Het
Dnah11	T	C	12: 118,024,045 (GRCm39)	E1902G	probably damaging	Het
Dst	A	G	1: 34,229,571 (GRCm39)	D2063G	probably damaging	Het
Furin	A	G	7: 80,040,838 (GRCm39)	S667P	possibly damaging	Het
Glmp	T	A	3: 88,233,139 (GRCm39)	S92R	probably benign	Het
Gm11563	C	G	11: 99,549,298 (GRCm39)	C152S	unknown	Het
Gm3486	A	G	14: 41,206,518 (GRCm39)	V185A	probably benign	Het
Gvin2	G	A	7: 105,551,187 (GRCm39)	Q622*	probably null	Het
Hyal1	C	A	9: 107,456,369 (GRCm39)	A102E	probably damaging	Het
Invs	T	C	4: 48,421,785 (GRCm39)	C806R	probably benign	Het
L1td1	T	C	4: 98,621,933 (GRCm39)	V165A	probably benign	Het
Lama1	A	G	17: 68,120,861 (GRCm39)	T2666A		Het
Lrit1	G	C	14: 36,782,052 (GRCm39)	V242L	probably damaging	Het
Lrrc8a	A	G	2: 30,146,239 (GRCm39)	Y351C	probably damaging	Het
Myh7b	T	C	2: 155,464,152 (GRCm39)	F551S	possibly damaging	Het
Myo19	A	G	11: 84,788,386 (GRCm39)	T333A	probably benign	Het
Nrp2	A	T	1: 62,799,947 (GRCm39)	N387I	probably damaging	Het
Oas2	T	C	5: 120,874,204 (GRCm39)	D543G	probably benign	Het
Or2g25	A	G	17: 37,970,405 (GRCm39)	I273T	possibly damaging	Het
Or5al6	A	G	2: 85,976,428 (GRCm39)	S217P	probably damaging	Het
Pak5	A	G	2: 135,942,859 (GRCm39)	V427A	probably benign	Het
Pfas	G	A	11: 68,891,356 (GRCm39)	A247V	probably benign	Het
Pramel52-ps	C	T	5: 94,531,490 (GRCm39)	H125Y	possibly damaging	Het
Psat1	T	A	19: 15,894,545 (GRCm39)	T115S	probably benign	Het
Psme4	T	A	11: 30,787,437 (GRCm39)	D1077E	probably benign	Het
Rabgap1l	A	G	1: 160,509,752 (GRCm39)	S442P	probably benign	Het
Ralgapa1	A	G	12: 55,822,976 (GRCm39)	M280T	possibly damaging	Het
Rb1cc1	A	T	1: 6,331,256 (GRCm39)	E394D	probably damaging	Het
Seh1l	T	C	18: 67,922,460 (GRCm39)	V271A	probably benign	Het
Sf3b1	A	T	1: 55,036,315 (GRCm39)	N919K	probably benign	Het
Sftpd	A	G	14: 40,896,449 (GRCm39)	S245P	possibly damaging	Het
Slc22a15	T	C	3: 101,831,430 (GRCm39)	E2G	probably damaging	Het
Spta1	A	G	1: 174,036,891 (GRCm39)	D1134G	possibly damaging	Het
Syna	A	G	5: 134,587,815 (GRCm39)	V378A	probably damaging	Het
Tchp	A	G	5: 114,847,411 (GRCm39)	K77E	possibly damaging	Het
Tescl	T	C	7: 24,032,956 (GRCm39)	N123S	probably benign	Het
Trio	C	T	15: 27,824,176 (GRCm39)	R1443Q	probably damaging	Het
Trrap	A	T	5: 144,727,665 (GRCm39)	Y462F	possibly damaging	Het
Vmn1r78	A	G	7: 11,886,832 (GRCm39)	T148A	probably benign	Het
Vmn2r111	T	C	17: 22,778,032 (GRCm39)	N549S	possibly damaging	Het
Zfp1007	A	C	5: 109,824,711 (GRCm39)	N246K	probably benign	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,820,730 (GRCm39)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,821,657 (GRCm39)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,830,163 (GRCm39)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,823,326 (GRCm39)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,807,863 (GRCm39)	missense	probably benign
IGL01554:Fsip2	APN	2	82,807,622 (GRCm39)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,821,430 (GRCm39)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,808,691 (GRCm39)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,812,983 (GRCm39)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,815,273 (GRCm39)	missense	probably benign
IGL01918:Fsip2	APN	2	82,822,482 (GRCm39)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,824,349 (GRCm39)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,824,211 (GRCm39)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,822,204 (GRCm39)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,809,065 (GRCm39)	missense	probably benign
IGL02155:Fsip2	APN	2	82,828,696 (GRCm39)	missense	probably benign
IGL02219:Fsip2	APN	2	82,808,174 (GRCm39)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,813,116 (GRCm39)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,809,137 (GRCm39)	missense	probably benign
IGL02478:Fsip2	APN	2	82,814,736 (GRCm39)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,809,199 (GRCm39)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,822,347 (GRCm39)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,779,836 (GRCm39)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,823,407 (GRCm39)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,828,662 (GRCm39)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,812,501 (GRCm39)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,781,370 (GRCm39)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,823,839 (GRCm39)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,822,701 (GRCm39)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,813,398 (GRCm39)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,820,968 (GRCm39)	intron	probably benign
IGL03076:Fsip2	APN	2	82,812,482 (GRCm39)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,808,420 (GRCm39)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,807,737 (GRCm39)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,820,814 (GRCm39)	missense	probably benign
bubblegum	UTSW	2	82,823,184 (GRCm39)	missense	probably benign	0.16
Dao	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
engulf	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
envelope	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
gladius	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
glove	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
Katana	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
scarf	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
Sock	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
swaddle	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
wrap	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
Wrapper	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,818,756 (GRCm39)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,814,709 (GRCm39)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,814,706 (GRCm39)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,821,196 (GRCm39)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,822,416 (GRCm39)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,830,201 (GRCm39)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,817,299 (GRCm39)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,806,952 (GRCm39)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,809,317 (GRCm39)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,815,269 (GRCm39)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,821,465 (GRCm39)	missense	probably benign
R0149:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,811,151 (GRCm39)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,815,521 (GRCm39)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,816,240 (GRCm39)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,813,677 (GRCm39)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,805,849 (GRCm39)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,814,908 (GRCm39)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,821,419 (GRCm39)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,808,129 (GRCm39)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,777,296 (GRCm39)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,824,139 (GRCm39)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,807,877 (GRCm39)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,774,484 (GRCm39)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,819,302 (GRCm39)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,807,241 (GRCm39)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,816,513 (GRCm39)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,821,703 (GRCm39)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,812,683 (GRCm39)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,816,617 (GRCm39)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,815,828 (GRCm39)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,807,436 (GRCm39)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,828,375 (GRCm39)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,819,780 (GRCm39)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,818,805 (GRCm39)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,805,378 (GRCm39)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,821,844 (GRCm39)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,805,570 (GRCm39)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,805,361 (GRCm39)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,811,355 (GRCm39)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,820,107 (GRCm39)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,819,752 (GRCm39)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,816,096 (GRCm39)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,820,089 (GRCm39)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,828,407 (GRCm39)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,817,539 (GRCm39)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,810,155 (GRCm39)	missense	probably benign
R1520:Fsip2	UTSW	2	82,811,058 (GRCm39)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,811,931 (GRCm39)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,816,626 (GRCm39)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,808,861 (GRCm39)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,816,689 (GRCm39)	missense	probably benign
R1700:Fsip2	UTSW	2	82,822,081 (GRCm39)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,805,289 (GRCm39)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,820,256 (GRCm39)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,818,055 (GRCm39)	missense	possibly damaging	0.71
R1760:Fsip2	UTSW	2	82,815,240 (GRCm39)	missense	probably benign	0.07
R1760:Fsip2	UTSW	2	82,830,185 (GRCm39)	missense	possibly damaging	0.85
R1789:Fsip2	UTSW	2	82,807,906 (GRCm39)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,814,933 (GRCm39)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,823,601 (GRCm39)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,774,504 (GRCm39)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,813,772 (GRCm39)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,817,164 (GRCm39)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,811,127 (GRCm39)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,817,077 (GRCm39)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,810,902 (GRCm39)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,821,894 (GRCm39)	missense	probably benign
R1965:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,823,124 (GRCm39)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,810,175 (GRCm39)	missense	probably benign
R1988:Fsip2	UTSW	2	82,806,861 (GRCm39)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,813,076 (GRCm39)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,819,788 (GRCm39)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R2037:Fsip2	UTSW	2	82,808,856 (GRCm39)	missense	probably damaging	0.99
R2070:Fsip2	UTSW	2	82,806,699 (GRCm39)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	82,839,159 (GRCm39)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,818,923 (GRCm39)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,820,615 (GRCm39)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,807,823 (GRCm39)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,793,095 (GRCm39)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,805,437 (GRCm39)	missense	probably benign
R2344:Fsip2	UTSW	2	82,820,257 (GRCm39)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,806,593 (GRCm39)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,811,064 (GRCm39)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,815,685 (GRCm39)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,809,954 (GRCm39)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,816,782 (GRCm39)	missense	probably benign
R2511:Fsip2	UTSW	2	82,782,001 (GRCm39)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,808,511 (GRCm39)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,820,775 (GRCm39)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,809,389 (GRCm39)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,821,868 (GRCm39)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,816,854 (GRCm39)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,822,354 (GRCm39)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,817,071 (GRCm39)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,815,253 (GRCm39)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,810,602 (GRCm39)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,819,311 (GRCm39)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,808,561 (GRCm39)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,813,058 (GRCm39)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,781,290 (GRCm39)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,819,950 (GRCm39)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,816,759 (GRCm39)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,815,120 (GRCm39)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,789,006 (GRCm39)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,813,862 (GRCm39)	missense	probably benign
R4042:Fsip2	UTSW	2	82,813,896 (GRCm39)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,813,245 (GRCm39)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,817,413 (GRCm39)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,805,493 (GRCm39)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,808,201 (GRCm39)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,821,550 (GRCm39)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4458:Fsip2	UTSW	2	82,821,120 (GRCm39)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,782,009 (GRCm39)	missense	probably benign
R4549:Fsip2	UTSW	2	82,819,972 (GRCm39)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,815,297 (GRCm39)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,816,510 (GRCm39)	missense	possibly damaging	0.71
R4583:Fsip2	UTSW	2	82,809,017 (GRCm39)	missense	probably benign	0.33
R4618:Fsip2	UTSW	2	82,818,103 (GRCm39)	missense	probably benign
R4700:Fsip2	UTSW	2	82,817,373 (GRCm39)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,805,203 (GRCm39)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,805,697 (GRCm39)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,819,629 (GRCm39)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,812,452 (GRCm39)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,818,044 (GRCm39)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,818,786 (GRCm39)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,820,515 (GRCm39)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,815,815 (GRCm39)	missense	probably benign	0.26
R4840:Fsip2	UTSW	2	82,779,739 (GRCm39)	missense	probably benign	0.01
R4865:Fsip2	UTSW	2	82,821,295 (GRCm39)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,805,202 (GRCm39)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,818,438 (GRCm39)	missense	probably benign	0.02
R4911:Fsip2	UTSW	2	82,811,837 (GRCm39)	missense	possibly damaging	0.85
R4918:Fsip2	UTSW	2	82,824,114 (GRCm39)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,815,384 (GRCm39)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,807,758 (GRCm39)	missense	probably benign	0.03
R4950:Fsip2	UTSW	2	82,777,276 (GRCm39)	missense	probably damaging	0.97
R4959:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,816,222 (GRCm39)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,815,169 (GRCm39)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,809,773 (GRCm39)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,819,477 (GRCm39)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,818,836 (GRCm39)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,823,494 (GRCm39)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,821,460 (GRCm39)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,822,329 (GRCm39)	missense	probably benign
R5119:Fsip2	UTSW	2	82,818,535 (GRCm39)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,811,768 (GRCm39)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,808,916 (GRCm39)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,811,085 (GRCm39)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,813,338 (GRCm39)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,823,505 (GRCm39)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,808,925 (GRCm39)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,818,489 (GRCm39)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,820,185 (GRCm39)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,805,742 (GRCm39)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,821,262 (GRCm39)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,812,572 (GRCm39)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,810,230 (GRCm39)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,815,654 (GRCm39)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,815,542 (GRCm39)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,781,256 (GRCm39)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,781,252 (GRCm39)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,817,403 (GRCm39)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,812,207 (GRCm39)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,793,090 (GRCm39)	missense	probably benign
R5568:Fsip2	UTSW	2	82,816,908 (GRCm39)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,828,472 (GRCm39)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,818,439 (GRCm39)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,817,838 (GRCm39)	nonsense	probably null
R5712:Fsip2	UTSW	2	82,839,192 (GRCm39)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,808,260 (GRCm39)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,815,084 (GRCm39)	missense	probably benign
R5881:Fsip2	UTSW	2	82,814,785 (GRCm39)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,822,953 (GRCm39)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,818,852 (GRCm39)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,817,092 (GRCm39)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,807,835 (GRCm39)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,793,657 (GRCm39)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,820,812 (GRCm39)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,818,283 (GRCm39)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,822,471 (GRCm39)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,816,017 (GRCm39)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,809,777 (GRCm39)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,821,388 (GRCm39)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,824,112 (GRCm39)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,818,289 (GRCm39)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,817,601 (GRCm39)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,811,071 (GRCm39)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,812,798 (GRCm39)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,820,227 (GRCm39)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,818,762 (GRCm39)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,810,785 (GRCm39)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,819,242 (GRCm39)	missense	probably benign	0.16
R6349:Fsip2	UTSW	2	82,823,416 (GRCm39)	missense	probably benign	0.05
R6351:Fsip2	UTSW	2	82,823,028 (GRCm39)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,813,836 (GRCm39)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,812,657 (GRCm39)	missense	probably benign
R6621:Fsip2	UTSW	2	82,820,158 (GRCm39)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,813,571 (GRCm39)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,798,161 (GRCm39)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,820,430 (GRCm39)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,809,878 (GRCm39)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,808,738 (GRCm39)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,816,776 (GRCm39)	missense	probably benign
R6790:Fsip2	UTSW	2	82,821,283 (GRCm39)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,819,838 (GRCm39)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,811,303 (GRCm39)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,815,544 (GRCm39)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,813,969 (GRCm39)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,813,131 (GRCm39)	missense	probably benign	0.26
R6950:Fsip2	UTSW	2	82,816,332 (GRCm39)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,812,293 (GRCm39)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,809,061 (GRCm39)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,778,630 (GRCm39)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,807,298 (GRCm39)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,817,269 (GRCm39)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,820,979 (GRCm39)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,821,235 (GRCm39)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,811,078 (GRCm39)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,813,496 (GRCm39)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,817,968 (GRCm39)	missense	probably benign
R7126:Fsip2	UTSW	2	82,813,485 (GRCm39)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,813,085 (GRCm39)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,811,541 (GRCm39)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,816,571 (GRCm39)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,823,581 (GRCm39)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,819,412 (GRCm39)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,814,015 (GRCm39)	missense	probably benign
R7228:Fsip2	UTSW	2	82,822,651 (GRCm39)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,812,484 (GRCm39)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,823,607 (GRCm39)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,809,425 (GRCm39)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,812,474 (GRCm39)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,810,863 (GRCm39)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,820,035 (GRCm39)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,819,860 (GRCm39)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,813,462 (GRCm39)	missense	probably benign
R7343:Fsip2	UTSW	2	82,809,711 (GRCm39)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,828,524 (GRCm39)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,819,140 (GRCm39)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,820,663 (GRCm39)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,815,601 (GRCm39)	missense	possibly damaging	0.53
R7426:Fsip2	UTSW	2	82,810,441 (GRCm39)	missense	probably damaging	0.98
R7450:Fsip2	UTSW	2	82,782,024 (GRCm39)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,818,894 (GRCm39)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,815,196 (GRCm39)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,824,337 (GRCm39)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,819,361 (GRCm39)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,805,585 (GRCm39)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,817,256 (GRCm39)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,807,886 (GRCm39)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,812,149 (GRCm39)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,820,455 (GRCm39)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,811,252 (GRCm39)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,818,723 (GRCm39)	missense	probably benign
R7811:Fsip2	UTSW	2	82,828,797 (GRCm39)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,807,044 (GRCm39)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,779,856 (GRCm39)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,808,168 (GRCm39)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,781,365 (GRCm39)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,816,120 (GRCm39)	missense	possibly damaging	0.51
R8009:Fsip2	UTSW	2	82,818,793 (GRCm39)	missense	possibly damaging	0.85
R8031:Fsip2	UTSW	2	82,817,235 (GRCm39)	missense	probably benign
R8034:Fsip2	UTSW	2	82,819,699 (GRCm39)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,816,322 (GRCm39)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,789,017 (GRCm39)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,823,296 (GRCm39)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,806,141 (GRCm39)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,818,021 (GRCm39)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,815,088 (GRCm39)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,806,951 (GRCm39)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,820,808 (GRCm39)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,808,487 (GRCm39)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,819,687 (GRCm39)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,811,346 (GRCm39)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,818,724 (GRCm39)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,821,099 (GRCm39)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,818,198 (GRCm39)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,822,239 (GRCm39)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8419:Fsip2	UTSW	2	82,808,963 (GRCm39)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,811,910 (GRCm39)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,807,430 (GRCm39)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,814,937 (GRCm39)	missense	probably benign
R8459:Fsip2	UTSW	2	82,810,022 (GRCm39)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,810,284 (GRCm39)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,777,336 (GRCm39)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,821,871 (GRCm39)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,815,246 (GRCm39)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,811,453 (GRCm39)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,815,822 (GRCm39)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,813,453 (GRCm39)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,821,606 (GRCm39)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,810,521 (GRCm39)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,820,782 (GRCm39)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,809,524 (GRCm39)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,807,681 (GRCm39)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,816,984 (GRCm39)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,810,938 (GRCm39)	missense	probably benign
R8926:Fsip2	UTSW	2	82,823,927 (GRCm39)	missense	possibly damaging	0.84
R8991:Fsip2	UTSW	2	82,815,370 (GRCm39)	missense	probably benign	0.33
R9014:Fsip2	UTSW	2	82,806,898 (GRCm39)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,817,075 (GRCm39)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,828,545 (GRCm39)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,806,180 (GRCm39)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,807,301 (GRCm39)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,816,103 (GRCm39)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,813,170 (GRCm39)	missense	probably benign
R9149:Fsip2	UTSW	2	82,812,374 (GRCm39)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,815,574 (GRCm39)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,817,844 (GRCm39)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,820,425 (GRCm39)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,823,062 (GRCm39)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,815,958 (GRCm39)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,807,662 (GRCm39)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,818,604 (GRCm39)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,818,747 (GRCm39)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,811,039 (GRCm39)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,822,756 (GRCm39)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,819,793 (GRCm39)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,805,907 (GRCm39)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,816,702 (GRCm39)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,806,132 (GRCm39)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,817,285 (GRCm39)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,793,062 (GRCm39)	missense	probably benign
R9523:Fsip2	UTSW	2	82,807,972 (GRCm39)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,798,173 (GRCm39)	missense	probably benign
R9636:Fsip2	UTSW	2	82,820,563 (GRCm39)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,821,984 (GRCm39)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,819,272 (GRCm39)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,806,226 (GRCm39)	missense	probably benign
R9705:Fsip2	UTSW	2	82,823,634 (GRCm39)	missense	probably benign
R9739:Fsip2	UTSW	2	82,823,896 (GRCm39)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,818,241 (GRCm39)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,821,994 (GRCm39)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,810,225 (GRCm39)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,821,865 (GRCm39)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,822,876 (GRCm39)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,808,184 (GRCm39)	missense	probably benign
RF028:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,824,352 (GRCm39)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,814,707 (GRCm39)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,812,851 (GRCm39)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,781,364 (GRCm39)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,785,290 (GRCm39)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,807,122 (GRCm39)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,817,807 (GRCm39)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,818,978 (GRCm39)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,817,997 (GRCm39)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,805,792 (GRCm39)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,820,009 (GRCm39)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,814,868 (GRCm39)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,777,304 (GRCm39)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,817,547 (GRCm39)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- TTGACTCCAATTCAGTGTGCAG -3'
(R):5'- AATCTTCAAATGCAGATGTAGGGG -3'

Sequencing Primer
(F):5'- CTCCAATTCAGTGTGCAGAAGTTGAC -3'
(R):5'- GAGCCACAGTGTTTCAAAAGGTTTG -3'

Posted On

2018-11-28