Mutagenetix > Incidental Mutation

Incidental Mutation 'R6968:Tenm3'

542112

Institutional Source

Beutler Lab

Gene Symbol

Tenm3

Ensembl Gene

ENSMUSG00000031561

Gene Name

teneurin transmembrane protein 3

Synonyms

Odz3, Ten-m3, 2610100B16Rik

MMRRC Submission

045078-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.472) question?

Stock #

R6968 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

48680717-49296986 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 48689474 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Asparagine at position 2038 (D2038N)

Ref Sequence

ENSEMBL: ENSMUSP00000033965 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033965] [ENSMUST00000190840]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000033965
AA Change: D2038N

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000033965
Gene: ENSMUSG00000031561
AA Change: D2038N

Domain	Start	End	E-Value	Type
Pfam:Ten_N	11	177	6.9e-91	PFAM
Pfam:Ten_N	171	308	1e-72	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2631	2708	1.5e-34	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000190840
AA Change: D2022N

PolyPhen 2 Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000140141
Gene: ENSMUSG00000031561
AA Change: D2022N

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	182	7.6e-77	PFAM
Pfam:Ten_N	168	308	6.6e-50	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2630	2708	3.2e-35	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.2%
20x: 97.1%

Validation Efficiency

97% (57/59)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large transmembrane protein that may be involved in the regulation of neuronal development. Mutation in this gene causes microphthalmia. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 62 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Apip	C	T	2: 102,919,798 (GRCm39)	L125F	possibly damaging	Het
Arfgef1	T	C	1: 10,223,903 (GRCm39)	Q1465R	probably damaging	Het
Arfgef1	G	T	1: 10,223,904 (GRCm39)	Q1465K	probably damaging	Het
Arhgef5	T	C	6: 43,252,276 (GRCm39)	V1009A	probably benign	Het
Asah2	A	T	19: 31,989,913 (GRCm39)	I489K	probably benign	Het
Bace1	A	G	9: 45,766,263 (GRCm39)		probably null	Het
Bhlhe40	TG	TGG	6: 108,641,818 (GRCm39)	254	probably null	Het
Ccdc162	T	C	10: 41,549,840 (GRCm39)	T348A	possibly damaging	Het
Cdkn2aip	C	A	8: 48,166,922 (GRCm39)		probably benign	Het
Cep78	A	C	19: 15,959,102 (GRCm39)	F111V	probably benign	Het
Chd4	T	A	6: 125,085,281 (GRCm39)	L784Q	probably damaging	Het
Chrna6	C	T	8: 27,896,683 (GRCm39)	C398Y	probably benign	Het
Cmip	T	C	8: 118,103,895 (GRCm39)	Y128H	probably damaging	Het
Cpne2	C	T	8: 95,275,130 (GRCm39)	P46L	probably damaging	Het
Cyp2w1	A	G	5: 139,339,746 (GRCm39)	Q112R	probably damaging	Het
Entpd3	A	T	9: 120,389,722 (GRCm39)	E336V	probably benign	Het
Fbxw28	A	C	9: 109,159,856 (GRCm39)	S197A	probably benign	Het
Foxk2	T	C	11: 121,151,308 (GRCm39)	F118L	possibly damaging	Het
Golm1	ACTTCTTCT	ACTTCT	13: 59,797,390 (GRCm39)		probably benign	Het
Hinfp	A	C	9: 44,209,282 (GRCm39)	S306A	probably benign	Het
Hspg2	T	A	4: 137,262,467 (GRCm39)	V1663E	probably damaging	Het
Inpp4b	T	C	8: 82,571,086 (GRCm39)	I125T	probably benign	Het
Jag2	C	T	12: 112,877,878 (GRCm39)	E592K	probably benign	Het
Krt23	T	A	11: 99,371,900 (GRCm39)	E317V	probably damaging	Het
Ltbp2	C	T	12: 84,835,857 (GRCm39)		probably null	Het
Mast4	G	T	13: 102,934,586 (GRCm39)	N152K	probably damaging	Het
Mast4	C	T	13: 102,941,155 (GRCm39)	V301I	probably damaging	Het
Mier2	G	A	10: 79,376,476 (GRCm39)		probably benign	Het
Mmp9	A	G	2: 164,794,860 (GRCm39)	T584A	probably benign	Het
Necab1	T	C	4: 14,957,852 (GRCm39)	E335G	probably damaging	Het
Nlrp9b	T	A	7: 19,783,433 (GRCm39)	N925K	probably damaging	Het
Nr4a2	T	C	2: 56,998,758 (GRCm39)		probably null	Het
Nrg2	T	C	18: 36,329,499 (GRCm39)	I239V	probably benign	Het
Nsun2	A	G	13: 69,779,409 (GRCm39)	D562G	probably benign	Het
Odad2	T	C	18: 7,273,155 (GRCm39)		probably null	Het
Or1e31	A	G	11: 73,690,205 (GRCm39)	I126T	possibly damaging	Het
Ormdl3	T	A	11: 98,474,941 (GRCm39)	M1L	probably benign	Het
Pcdh10	T	A	3: 45,333,977 (GRCm39)	V97D	probably damaging	Het
Pde3a	T	C	6: 141,433,658 (GRCm39)	F847L	probably damaging	Het
Ppp1r13b	C	A	12: 111,799,612 (GRCm39)	V722F	possibly damaging	Het
Rhoh	A	G	5: 66,049,862 (GRCm39)	D44G	possibly damaging	Het
Riox1	C	T	12: 83,998,147 (GRCm39)	R228C	probably damaging	Het
Rtl1	C	T	12: 109,561,113 (GRCm39)	R242Q	unknown	Het
Saxo2	T	C	7: 82,292,969 (GRCm39)	T43A	probably damaging	Het
Sec16a	G	A	2: 26,320,498 (GRCm39)	R1361C	probably damaging	Het
Sema3f	C	T	9: 107,568,648 (GRCm39)		probably null	Het
Snap25	T	C	2: 136,611,690 (GRCm39)	M64T	probably benign	Het
Spef2	T	C	15: 9,597,426 (GRCm39)	N1410S	probably benign	Het
Sstr2	T	C	11: 113,515,774 (GRCm39)	I231T	probably damaging	Het
Stam	A	T	2: 14,120,829 (GRCm39)	H78L	probably damaging	Het
Suox	C	T	10: 128,507,702 (GRCm39)	V109I	possibly damaging	Het
Syne1	T	C	10: 5,067,041 (GRCm39)	R7075G	probably benign	Het
Tln1	C	T	4: 43,550,217 (GRCm39)	R482Q	probably benign	Het
Tnrc6a	T	C	7: 122,781,650 (GRCm39)	V1440A	probably benign	Het
Togaram2	A	G	17: 72,016,608 (GRCm39)	D655G	probably damaging	Het
Trgv2	A	T	13: 19,520,896 (GRCm39)	I66K	probably damaging	Het
Vmn1r113	A	T	7: 20,521,876 (GRCm39)	I223F	probably damaging	Het
Vmn2r62	T	A	7: 42,437,866 (GRCm39)	H206L	probably benign	Het
Zan	T	A	5: 137,460,075 (GRCm39)	Y1272F	unknown	Het
Zfp39	T	C	11: 58,782,306 (GRCm39)	H152R	probably benign	Het
Zfp41	T	A	15: 75,490,310 (GRCm39)	Y87*	probably null	Het
Zfp933	A	T	4: 147,910,654 (GRCm39)	L314H	probably damaging	Het

Other mutations in Tenm3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Tenm3	APN	8	48,870,095 (GRCm39)	missense	probably damaging	1.00
IGL00538:Tenm3	APN	8	48,689,060 (GRCm39)	missense	probably damaging	1.00
IGL00719:Tenm3	APN	8	48,732,077 (GRCm39)	missense	probably benign	0.39
IGL00720:Tenm3	APN	8	48,729,456 (GRCm39)	missense	probably damaging	0.98
IGL00870:Tenm3	APN	8	48,870,167 (GRCm39)	missense	probably benign	0.00
IGL00976:Tenm3	APN	8	48,709,876 (GRCm39)	missense	probably benign	0.14
IGL01469:Tenm3	APN	8	48,689,458 (GRCm39)	missense	probably damaging	1.00
IGL01508:Tenm3	APN	8	48,729,680 (GRCm39)	missense	probably benign	0.09
IGL01590:Tenm3	APN	8	48,681,837 (GRCm39)	missense	probably damaging	1.00
IGL01610:Tenm3	APN	8	48,707,512 (GRCm39)	missense	probably damaging	1.00
IGL01874:Tenm3	APN	8	48,689,793 (GRCm39)	nonsense	probably null
IGL01892:Tenm3	APN	8	48,729,431 (GRCm39)	missense	probably benign	0.09
IGL02098:Tenm3	APN	8	48,729,611 (GRCm39)	missense	possibly damaging	0.94
IGL02382:Tenm3	APN	8	48,688,511 (GRCm39)	missense	probably damaging	1.00
IGL02397:Tenm3	APN	8	48,689,729 (GRCm39)	missense	possibly damaging	0.94
IGL02475:Tenm3	APN	8	48,732,233 (GRCm39)	splice site	probably benign
IGL02502:Tenm3	APN	8	48,741,051 (GRCm39)	missense	probably damaging	1.00
IGL02508:Tenm3	APN	8	48,752,674 (GRCm39)	missense	probably benign	0.30
IGL02543:Tenm3	APN	8	48,751,991 (GRCm39)	missense	probably damaging	1.00
IGL02723:Tenm3	APN	8	48,729,938 (GRCm39)	missense	probably benign	0.02
IGL03037:Tenm3	APN	8	48,751,913 (GRCm39)	missense	possibly damaging	0.90
IGL03160:Tenm3	APN	8	49,099,453 (GRCm39)	missense	probably benign	0.05
IGL03268:Tenm3	APN	8	48,688,558 (GRCm39)	missense	probably damaging	1.00
IGL02988:Tenm3	UTSW	8	48,688,381 (GRCm39)	missense	probably damaging	0.99
PIT4431001:Tenm3	UTSW	8	48,688,642 (GRCm39)	missense	probably damaging	1.00
PIT4504001:Tenm3	UTSW	8	48,746,692 (GRCm39)	missense	probably damaging	1.00
R0079:Tenm3	UTSW	8	48,796,380 (GRCm39)	missense	possibly damaging	0.90
R0121:Tenm3	UTSW	8	48,795,694 (GRCm39)	missense	probably damaging	0.99
R0123:Tenm3	UTSW	8	49,127,507 (GRCm39)	missense	probably damaging	1.00
R0134:Tenm3	UTSW	8	49,127,507 (GRCm39)	missense	probably damaging	1.00
R0147:Tenm3	UTSW	8	48,689,755 (GRCm39)	missense	probably damaging	1.00
R0148:Tenm3	UTSW	8	48,689,755 (GRCm39)	missense	probably damaging	1.00
R0309:Tenm3	UTSW	8	48,794,069 (GRCm39)	missense	probably damaging	1.00
R0322:Tenm3	UTSW	8	48,689,947 (GRCm39)	splice site	probably benign
R0335:Tenm3	UTSW	8	48,685,140 (GRCm39)	missense	probably damaging	1.00
R0355:Tenm3	UTSW	8	48,682,010 (GRCm39)	missense	probably damaging	1.00
R0411:Tenm3	UTSW	8	48,740,826 (GRCm39)	missense	possibly damaging	0.61
R0505:Tenm3	UTSW	8	48,794,195 (GRCm39)	splice site	probably benign
R0573:Tenm3	UTSW	8	49,127,434 (GRCm39)	splice site	probably benign
R0599:Tenm3	UTSW	8	48,730,745 (GRCm39)	missense	probably damaging	1.00
R0616:Tenm3	UTSW	8	48,729,191 (GRCm39)	missense	possibly damaging	0.76
R0637:Tenm3	UTSW	8	48,689,560 (GRCm39)	missense	probably damaging	1.00
R0726:Tenm3	UTSW	8	48,689,629 (GRCm39)	missense	probably damaging	1.00
R0840:Tenm3	UTSW	8	48,788,777 (GRCm39)	missense	probably damaging	0.99
R0981:Tenm3	UTSW	8	48,752,000 (GRCm39)	missense	probably damaging	1.00
R1006:Tenm3	UTSW	8	48,681,577 (GRCm39)	missense	probably damaging	1.00
R1199:Tenm3	UTSW	8	48,688,617 (GRCm39)	missense	probably damaging	0.99
R1223:Tenm3	UTSW	8	48,693,431 (GRCm39)	missense	possibly damaging	0.72
R1240:Tenm3	UTSW	8	48,740,928 (GRCm39)	missense	possibly damaging	0.74
R1394:Tenm3	UTSW	8	48,729,435 (GRCm39)	missense	probably benign
R1455:Tenm3	UTSW	8	48,732,083 (GRCm39)	missense	possibly damaging	0.87
R1459:Tenm3	UTSW	8	48,689,006 (GRCm39)	missense	probably damaging	1.00
R1473:Tenm3	UTSW	8	48,763,660 (GRCm39)	missense	probably damaging	1.00
R1501:Tenm3	UTSW	8	48,796,351 (GRCm39)	missense	probably damaging	0.99
R1507:Tenm3	UTSW	8	48,740,857 (GRCm39)	missense	probably benign	0.01
R1522:Tenm3	UTSW	8	48,848,611 (GRCm39)	missense	probably damaging	1.00
R1524:Tenm3	UTSW	8	48,682,016 (GRCm39)	missense	possibly damaging	0.92
R1553:Tenm3	UTSW	8	48,689,456 (GRCm39)	missense	probably damaging	1.00
R1572:Tenm3	UTSW	8	48,682,028 (GRCm39)	missense	possibly damaging	0.94
R1583:Tenm3	UTSW	8	48,732,109 (GRCm39)	missense	probably benign	0.09
R1676:Tenm3	UTSW	8	48,870,154 (GRCm39)	missense	possibly damaging	0.83
R1732:Tenm3	UTSW	8	48,763,669 (GRCm39)	missense	probably damaging	1.00
R1768:Tenm3	UTSW	8	48,685,139 (GRCm39)	missense	probably damaging	1.00
R1777:Tenm3	UTSW	8	48,870,214 (GRCm39)	missense	probably benign	0.05
R1793:Tenm3	UTSW	8	49,127,579 (GRCm39)	missense	probably damaging	0.98
R1801:Tenm3	UTSW	8	48,729,291 (GRCm39)	missense	probably benign	0.39
R1863:Tenm3	UTSW	8	48,729,381 (GRCm39)	missense	probably benign	0.20
R1898:Tenm3	UTSW	8	48,763,796 (GRCm39)	missense	probably damaging	1.00
R1971:Tenm3	UTSW	8	48,689,348 (GRCm39)	missense	probably damaging	1.00
R1972:Tenm3	UTSW	8	48,681,626 (GRCm39)	missense	probably damaging	1.00
R1996:Tenm3	UTSW	8	48,681,703 (GRCm39)	missense	probably damaging	1.00
R2061:Tenm3	UTSW	8	48,795,291 (GRCm39)	critical splice donor site	probably null
R2109:Tenm3	UTSW	8	48,796,384 (GRCm39)	missense	possibly damaging	0.94
R2124:Tenm3	UTSW	8	48,870,041 (GRCm39)	critical splice donor site	probably null
R2190:Tenm3	UTSW	8	48,848,579 (GRCm39)	missense	probably damaging	1.00
R2204:Tenm3	UTSW	8	49,127,585 (GRCm39)	missense	probably benign	0.17
R2233:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2234:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2235:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2237:Tenm3	UTSW	8	48,795,372 (GRCm39)	missense	probably damaging	1.00
R2418:Tenm3	UTSW	8	48,729,693 (GRCm39)	missense	possibly damaging	0.87
R2419:Tenm3	UTSW	8	48,729,693 (GRCm39)	missense	possibly damaging	0.87
R2435:Tenm3	UTSW	8	48,740,988 (GRCm39)	missense	probably damaging	1.00
R2483:Tenm3	UTSW	8	48,693,305 (GRCm39)	missense	probably damaging	0.99
R3406:Tenm3	UTSW	8	48,681,590 (GRCm39)	missense	probably damaging	1.00
R3724:Tenm3	UTSW	8	48,730,781 (GRCm39)	missense	probably damaging	0.97
R4009:Tenm3	UTSW	8	48,802,258 (GRCm39)	missense	probably damaging	1.00
R4210:Tenm3	UTSW	8	48,802,439 (GRCm39)	missense	probably damaging	1.00
R4293:Tenm3	UTSW	8	48,848,693 (GRCm39)	missense	probably damaging	1.00
R4656:Tenm3	UTSW	8	48,746,761 (GRCm39)	missense	probably damaging	1.00
R4663:Tenm3	UTSW	8	48,689,005 (GRCm39)	missense	probably damaging	1.00
R4835:Tenm3	UTSW	8	48,766,271 (GRCm39)	critical splice donor site	probably null
R4851:Tenm3	UTSW	8	48,763,656 (GRCm39)	critical splice donor site	probably null
R4867:Tenm3	UTSW	8	48,688,856 (GRCm39)	missense	probably damaging	1.00
R4892:Tenm3	UTSW	8	48,729,896 (GRCm39)	missense	probably damaging	0.99
R4895:Tenm3	UTSW	8	48,754,006 (GRCm39)	missense	probably damaging	1.00
R4962:Tenm3	UTSW	8	48,731,996 (GRCm39)	nonsense	probably null
R4995:Tenm3	UTSW	8	48,682,172 (GRCm39)	missense	possibly damaging	0.87
R4996:Tenm3	UTSW	8	48,688,861 (GRCm39)	missense	probably damaging	0.97
R5091:Tenm3	UTSW	8	48,795,343 (GRCm39)	missense	probably benign	0.14
R5228:Tenm3	UTSW	8	48,689,390 (GRCm39)	missense	probably damaging	1.00
R5253:Tenm3	UTSW	8	48,682,233 (GRCm39)	missense	possibly damaging	0.92
R5260:Tenm3	UTSW	8	48,689,890 (GRCm39)	missense	probably damaging	1.00
R5363:Tenm3	UTSW	8	48,740,866 (GRCm39)	missense	possibly damaging	0.55
R5414:Tenm3	UTSW	8	48,689,390 (GRCm39)	missense	probably damaging	1.00
R5427:Tenm3	UTSW	8	48,689,599 (GRCm39)	missense	probably damaging	1.00
R5431:Tenm3	UTSW	8	48,820,412 (GRCm39)	nonsense	probably null
R5566:Tenm3	UTSW	8	48,732,041 (GRCm39)	missense	probably damaging	1.00
R5579:Tenm3	UTSW	8	48,689,799 (GRCm39)	missense	probably damaging	1.00
R5656:Tenm3	UTSW	8	48,681,797 (GRCm39)	missense	probably damaging	1.00
R5931:Tenm3	UTSW	8	49,099,533 (GRCm39)	missense	probably benign	0.00
R5959:Tenm3	UTSW	8	49,099,482 (GRCm39)	nonsense	probably null
R5965:Tenm3	UTSW	8	48,681,543 (GRCm39)	nonsense	probably null
R6062:Tenm3	UTSW	8	48,796,441 (GRCm39)	missense	possibly damaging	0.46
R6151:Tenm3	UTSW	8	48,848,608 (GRCm39)	missense	probably damaging	1.00
R6157:Tenm3	UTSW	8	48,751,843 (GRCm39)	missense	probably damaging	0.96
R6167:Tenm3	UTSW	8	48,707,657 (GRCm39)	missense	possibly damaging	0.46
R6217:Tenm3	UTSW	8	48,746,700 (GRCm39)	missense	probably damaging	0.99
R6233:Tenm3	UTSW	8	48,870,094 (GRCm39)	missense	probably damaging	1.00
R6270:Tenm3	UTSW	8	48,820,429 (GRCm39)	missense	probably damaging	0.98
R6329:Tenm3	UTSW	8	48,729,884 (GRCm39)	missense	probably damaging	0.99
R6466:Tenm3	UTSW	8	48,689,098 (GRCm39)	missense	probably damaging	0.97
R6515:Tenm3	UTSW	8	48,870,257 (GRCm39)	missense	probably benign
R6516:Tenm3	UTSW	8	48,870,257 (GRCm39)	missense	probably benign
R6747:Tenm3	UTSW	8	48,796,278 (GRCm39)	missense	probably damaging	1.00
R6782:Tenm3	UTSW	8	49,099,291 (GRCm39)	critical splice donor site	probably null
R6788:Tenm3	UTSW	8	49,127,528 (GRCm39)	missense	probably damaging	1.00
R6823:Tenm3	UTSW	8	48,709,872 (GRCm39)	missense	probably damaging	0.99
R6846:Tenm3	UTSW	8	48,729,773 (GRCm39)	missense	probably benign	0.39
R6913:Tenm3	UTSW	8	48,751,972 (GRCm39)	missense	probably damaging	0.99
R6941:Tenm3	UTSW	8	49,127,451 (GRCm39)	missense	probably damaging	0.99
R6950:Tenm3	UTSW	8	48,693,514 (GRCm39)	nonsense	probably null
R6970:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R6993:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R7003:Tenm3	UTSW	8	48,693,479 (GRCm39)	missense	probably damaging	1.00
R7125:Tenm3	UTSW	8	49,127,588 (GRCm39)	missense	probably benign	0.00
R7140:Tenm3	UTSW	8	48,745,271 (GRCm39)	missense	probably damaging	1.00
R7222:Tenm3	UTSW	8	48,754,004 (GRCm39)	missense	probably damaging	1.00
R7232:Tenm3	UTSW	8	48,688,970 (GRCm39)	missense	probably damaging	1.00
R7336:Tenm3	UTSW	8	48,689,212 (GRCm39)	missense	possibly damaging	0.93
R7417:Tenm3	UTSW	8	48,689,218 (GRCm39)	missense	probably damaging	1.00
R7526:Tenm3	UTSW	8	48,740,847 (GRCm39)	missense	probably damaging	0.96
R7527:Tenm3	UTSW	8	48,729,635 (GRCm39)	missense	possibly damaging	0.60
R7616:Tenm3	UTSW	8	48,794,084 (GRCm39)	missense	possibly damaging	0.56
R7662:Tenm3	UTSW	8	48,788,762 (GRCm39)	missense	probably benign	0.27
R7734:Tenm3	UTSW	8	49,099,368 (GRCm39)	missense	probably damaging	1.00
R7802:Tenm3	UTSW	8	48,689,500 (GRCm39)	missense	probably damaging	1.00
R7812:Tenm3	UTSW	8	48,729,335 (GRCm39)	missense	probably benign	0.01
R7843:Tenm3	UTSW	8	48,682,146 (GRCm39)	nonsense	probably null
R7951:Tenm3	UTSW	8	48,763,738 (GRCm39)	missense	possibly damaging	0.86
R8293:Tenm3	UTSW	8	48,820,457 (GRCm39)	missense	possibly damaging	0.91
R8336:Tenm3	UTSW	8	48,746,808 (GRCm39)	missense	probably damaging	1.00
R8351:Tenm3	UTSW	8	48,740,907 (GRCm39)	missense	probably damaging	0.96
R8387:Tenm3	UTSW	8	48,740,883 (GRCm39)	missense	probably damaging	0.98
R8414:Tenm3	UTSW	8	48,746,544 (GRCm39)	missense	probably damaging	1.00
R8451:Tenm3	UTSW	8	48,740,907 (GRCm39)	missense	probably damaging	0.96
R8465:Tenm3	UTSW	8	48,682,216 (GRCm39)	missense	probably damaging	1.00
R8528:Tenm3	UTSW	8	48,795,668 (GRCm39)	missense	probably damaging	1.00
R8717:Tenm3	UTSW	8	48,752,680 (GRCm39)	missense	possibly damaging	0.77
R8734:Tenm3	UTSW	8	48,802,391 (GRCm39)	missense	probably benign	0.16
R8781:Tenm3	UTSW	8	48,795,484 (GRCm39)	frame shift	probably null
R8820:Tenm3	UTSW	8	48,763,759 (GRCm39)	missense	probably damaging	0.96
R8821:Tenm3	UTSW	8	48,729,417 (GRCm39)	missense
R8831:Tenm3	UTSW	8	48,729,417 (GRCm39)	missense
R8853:Tenm3	UTSW	8	48,795,382 (GRCm39)	missense	probably damaging	1.00
R8900:Tenm3	UTSW	8	48,689,437 (GRCm39)	missense	probably damaging	1.00
R8931:Tenm3	UTSW	8	48,688,637 (GRCm39)	missense	probably damaging	1.00
R8933:Tenm3	UTSW	8	48,732,095 (GRCm39)	missense	possibly damaging	0.53
R8989:Tenm3	UTSW	8	48,688,383 (GRCm39)	nonsense	probably null
R8998:Tenm3	UTSW	8	48,729,722 (GRCm39)	missense	probably damaging	1.00
R9008:Tenm3	UTSW	8	48,795,688 (GRCm39)	missense	probably damaging	0.98
R9017:Tenm3	UTSW	8	48,707,668 (GRCm39)	missense	probably damaging	0.99
R9101:Tenm3	UTSW	8	48,745,186 (GRCm39)	missense	probably damaging	1.00
R9108:Tenm3	UTSW	8	48,766,271 (GRCm39)	critical splice donor site	probably null
R9142:Tenm3	UTSW	8	48,788,548 (GRCm39)	missense	unknown
R9231:Tenm3	UTSW	8	48,689,231 (GRCm39)	missense	probably damaging	1.00
R9309:Tenm3	UTSW	8	48,751,972 (GRCm39)	missense	probably damaging	0.99
R9310:Tenm3	UTSW	8	49,008,935 (GRCm39)	unclassified	probably benign
R9336:Tenm3	UTSW	8	48,870,115 (GRCm39)	missense	probably damaging	1.00
R9373:Tenm3	UTSW	8	48,752,690 (GRCm39)	missense	probably damaging	1.00
R9393:Tenm3	UTSW	8	49,127,559 (GRCm39)	missense	probably damaging	0.99
R9509:Tenm3	UTSW	8	48,766,292 (GRCm39)	nonsense	probably null
R9575:Tenm3	UTSW	8	48,688,796 (GRCm39)	missense	possibly damaging	0.94
R9698:Tenm3	UTSW	8	48,689,246 (GRCm39)	missense	probably damaging	1.00
R9722:Tenm3	UTSW	8	48,753,849 (GRCm39)	missense	probably benign	0.00
R9788:Tenm3	UTSW	8	48,788,596 (GRCm39)	missense	probably benign	0.02
X0010:Tenm3	UTSW	8	48,740,864 (GRCm39)	missense	probably damaging	0.98
X0025:Tenm3	UTSW	8	48,689,512 (GRCm39)	missense	probably damaging	1.00
Z1177:Tenm3	UTSW	8	48,729,815 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- ATAAGTCATCACGGCCGTG -3'
(R):5'- AACGAGTCGGAGGGTCTTATTC -3'

Sequencing Primer
(F):5'- CACGGCCGTGGAAATGATTTG -3'
(R):5'- TACGACAGCACAAGAGTCAGTTTTAC -3'

Posted On

2018-11-28