Incidental Mutation 'R6980:Ift172'
| ID |
543760 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ift172
|
| Ensembl Gene |
ENSMUSG00000038564 |
| Gene Name |
intraflagellar transport 172 |
| Synonyms |
4930553F24Rik, wim, avc1 |
| MMRRC Submission |
045088-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R6980 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
31410623-31448458 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 31414730 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1390
(D1390G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049335
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041565]
[ENSMUST00000054829]
[ENSMUST00000201625]
[ENSMUST00000201937]
|
| AlphaFold |
Q6VH22 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041565
AA Change: D1390G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000049335
Gene: ENSMUSG00000038564
AA Change: D1390G
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
2 |
44 |
6e-3 |
SMART |
|
WD40
|
55 |
94 |
2.22e0 |
SMART |
|
WD40
|
102 |
139 |
1.23e2 |
SMART |
|
WD40
|
141 |
180 |
4.6e0 |
SMART |
|
WD40
|
186 |
223 |
3.3e1 |
SMART |
|
WD40
|
225 |
267 |
4.42e1 |
SMART |
|
WD40
|
279 |
314 |
1.03e1 |
SMART |
|
Blast:WD40
|
516 |
550 |
5e-13 |
BLAST |
|
low complexity region
|
573 |
588 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
625 |
1026 |
1.7e-10 |
PROSPERO |
|
Blast:TPR
|
1029 |
1062 |
2e-13 |
BLAST |
|
low complexity region
|
1077 |
1091 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1101 |
1498 |
1.7e-10 |
PROSPERO |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000054829
|
| SMART Domains |
Protein: ENSMUSP00000060414
Gene: ENSMUSG00000029149
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BCLP
|
19 |
211 |
8.6e-80 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201625
|
| SMART Domains |
Protein: ENSMUSP00000144052
Gene: ENSMUSG00000029149
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BCLP
|
19 |
206 |
1.8e-74 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000201937
|
| SMART Domains |
Protein: ENSMUSP00000144464
Gene: ENSMUSG00000029149
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BCLP
|
19 |
206 |
1.8e-74 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the intraflagellar transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are necessary for ciliary assembly and maintenance. Mutations in this gene have been associated with skeletal ciliopathies, with or without polydactyly, such as such short-rib thoracic dysplasias 1, 9 or 10. [provided by RefSeq, Mar 2014]
PHENOTYPE: Mice homozygous for disruptions in this gene display embryonic lethality during organogenesis, neural tube defects, and developmental patterning abnormalities. Mice homozygous for a conditional allele activated in the early limb bud exhibit polydactyly and short limbs. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca2 |
C |
A |
2: 25,330,878 (GRCm39) |
R1189S |
possibly damaging |
Het |
| Abcf2 |
T |
C |
5: 24,770,970 (GRCm39) |
Q594R |
probably benign |
Het |
| Abhd18 |
G |
A |
3: 40,888,215 (GRCm39) |
S353N |
probably benign |
Het |
| Adrb1 |
G |
T |
19: 56,712,046 (GRCm39) |
A415S |
probably benign |
Het |
| Art2b |
T |
C |
7: 101,229,680 (GRCm39) |
N73S |
probably benign |
Het |
| BC028528 |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
CTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTT |
3: 95,795,448 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
CACTGGTTCTGTGGT |
CACTGGTTCTGTGGTTACTGGTTCTGTGGT |
3: 95,795,480 (GRCm39) |
|
probably benign |
Het |
| BC028528 |
ACTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC |
ACTGGTTCTGTGGTCTCTGGTTCTGTGGTCACTGGTTCTGTGGTCACTGGTTCTGTGGTC |
3: 95,795,451 (GRCm39) |
|
probably benign |
Het |
| Cacna1a |
A |
G |
8: 85,338,914 (GRCm39) |
M1753V |
possibly damaging |
Het |
| Cbx8 |
A |
T |
11: 118,930,287 (GRCm39) |
I102N |
possibly damaging |
Het |
| Ccdc178 |
T |
A |
18: 22,238,620 (GRCm39) |
E332D |
probably benign |
Het |
| Cdhr17 |
T |
A |
5: 17,031,944 (GRCm39) |
V533D |
possibly damaging |
Het |
| Cfap74 |
G |
A |
4: 155,550,809 (GRCm39) |
|
probably benign |
Het |
| Chat |
A |
T |
14: 32,146,111 (GRCm39) |
M354K |
probably benign |
Het |
| Cmas |
A |
G |
6: 142,702,526 (GRCm39) |
T10A |
probably damaging |
Het |
| Cyb561d1 |
A |
T |
3: 108,107,475 (GRCm39) |
L51H |
probably benign |
Het |
| D030056L22Rik |
A |
T |
19: 18,694,629 (GRCm39) |
N128I |
probably damaging |
Het |
| D130043K22Rik |
G |
T |
13: 25,048,764 (GRCm39) |
A423S |
probably damaging |
Het |
| Dnah14 |
T |
C |
1: 181,475,795 (GRCm39) |
I1349T |
probably benign |
Het |
| Dnajb3 |
T |
G |
1: 88,132,736 (GRCm39) |
D222A |
probably damaging |
Het |
| Dtx1 |
T |
C |
5: 120,819,422 (GRCm39) |
E592G |
probably damaging |
Het |
| Dzank1 |
C |
T |
2: 144,332,056 (GRCm39) |
G427R |
possibly damaging |
Het |
| E130308A19Rik |
A |
C |
4: 59,719,991 (GRCm39) |
K508Q |
probably damaging |
Het |
| Eif4e1b |
T |
A |
13: 54,931,916 (GRCm39) |
|
probably null |
Het |
| Ell2 |
A |
G |
13: 75,904,495 (GRCm39) |
M159V |
probably null |
Het |
| Eml4 |
G |
A |
17: 83,758,446 (GRCm39) |
V377I |
probably benign |
Het |
| Fryl |
A |
T |
5: 73,207,773 (GRCm39) |
S2466T |
probably benign |
Het |
| Gfpt1 |
C |
A |
6: 87,054,071 (GRCm39) |
T426K |
probably damaging |
Het |
| Gm49355 |
T |
C |
14: 12,307,173 (GRCm38) |
|
probably benign |
Het |
| Gm5114 |
T |
C |
7: 39,058,624 (GRCm39) |
I332V |
probably benign |
Het |
| Gpr15 |
T |
A |
16: 58,539,105 (GRCm39) |
|
probably benign |
Het |
| Gpr179 |
T |
C |
11: 97,225,684 (GRCm39) |
E2157G |
probably benign |
Het |
| Gramd4 |
A |
G |
15: 86,016,170 (GRCm39) |
N482S |
probably benign |
Het |
| Hfm1 |
A |
T |
5: 107,028,343 (GRCm39) |
I829K |
probably benign |
Het |
| Hydin |
A |
T |
8: 111,139,916 (GRCm39) |
E728D |
possibly damaging |
Het |
| Ifngr2 |
T |
A |
16: 91,356,895 (GRCm39) |
V143E |
probably damaging |
Het |
| Kdf1 |
A |
T |
4: 133,256,138 (GRCm39) |
D285V |
probably damaging |
Het |
| Mast4 |
C |
T |
13: 102,941,155 (GRCm39) |
V301I |
probably damaging |
Het |
| Mdn1 |
G |
A |
4: 32,726,942 (GRCm39) |
|
probably null |
Het |
| Megf11 |
A |
G |
9: 64,613,132 (GRCm39) |
E1016G |
probably damaging |
Het |
| Mixl1 |
G |
A |
1: 180,524,453 (GRCm39) |
A42V |
possibly damaging |
Het |
| Mpp2 |
A |
G |
11: 101,950,154 (GRCm39) |
W567R |
probably damaging |
Het |
| Mrgpra6 |
A |
G |
7: 46,838,697 (GRCm39) |
L136P |
probably damaging |
Het |
| Mroh7 |
T |
A |
4: 106,557,434 (GRCm39) |
I759L |
probably benign |
Het |
| Nrxn2 |
A |
G |
19: 6,500,609 (GRCm39) |
D277G |
probably benign |
Het |
| Nup210l |
A |
T |
3: 90,027,234 (GRCm39) |
K205N |
probably benign |
Het |
| Or4g17 |
A |
G |
2: 111,209,620 (GRCm39) |
I92V |
possibly damaging |
Het |
| Or4p4b-ps1 |
A |
G |
2: 88,453,939 (GRCm39) |
*97W |
probably null |
Het |
| Or52e19b |
T |
C |
7: 103,032,303 (GRCm39) |
E302G |
probably benign |
Het |
| Or5al6 |
A |
T |
2: 85,976,681 (GRCm39) |
Y132* |
probably null |
Het |
| Oxnad1 |
C |
T |
14: 31,807,576 (GRCm39) |
|
probably benign |
Het |
| Pamr1 |
C |
T |
2: 102,472,549 (GRCm39) |
T616I |
probably benign |
Het |
| Pcdhgb5 |
C |
T |
18: 37,866,592 (GRCm39) |
H796Y |
possibly damaging |
Het |
| Pdlim7 |
G |
T |
13: 55,656,041 (GRCm39) |
D126E |
probably benign |
Het |
| Pfdn2 |
C |
T |
1: 171,185,465 (GRCm39) |
|
probably benign |
Het |
| Piezo2 |
T |
A |
18: 63,216,032 (GRCm39) |
|
probably null |
Het |
| Pms2 |
A |
T |
5: 143,848,842 (GRCm39) |
I43L |
probably benign |
Het |
| Prex2 |
T |
A |
1: 11,232,487 (GRCm39) |
S851R |
probably benign |
Het |
| Ptpn4 |
T |
A |
1: 119,671,151 (GRCm39) |
E202D |
possibly damaging |
Het |
| Rnf40 |
T |
A |
7: 127,193,849 (GRCm39) |
V455E |
probably damaging |
Het |
| Rp1l1 |
A |
G |
14: 64,266,169 (GRCm39) |
N585S |
probably benign |
Het |
| Rrp12 |
A |
G |
19: 41,878,582 (GRCm39) |
S188P |
probably damaging |
Het |
| Rsbn1l |
T |
A |
5: 21,101,482 (GRCm39) |
H686L |
probably benign |
Het |
| Runx2 |
C |
T |
17: 45,046,203 (GRCm39) |
V107I |
possibly damaging |
Het |
| Rusc2 |
A |
G |
4: 43,422,846 (GRCm39) |
I994M |
probably benign |
Het |
| Ryr1 |
T |
A |
7: 28,808,812 (GRCm39) |
D420V |
probably benign |
Het |
| Sash1 |
T |
C |
10: 8,605,612 (GRCm39) |
Q926R |
probably benign |
Het |
| Scgb3a2 |
T |
A |
18: 43,897,499 (GRCm39) |
I6N |
probably damaging |
Het |
| Sdc3 |
T |
A |
4: 130,544,233 (GRCm39) |
|
probably benign |
Het |
| Sik2 |
A |
G |
9: 50,808,755 (GRCm39) |
V658A |
probably benign |
Het |
| Slc25a39 |
A |
G |
11: 102,296,601 (GRCm39) |
V81A |
probably damaging |
Het |
| Snai2 |
T |
A |
16: 14,526,113 (GRCm39) |
S255T |
possibly damaging |
Het |
| Sorbs1 |
A |
T |
19: 40,316,060 (GRCm39) |
Y371* |
probably null |
Het |
| Spata31d1b |
A |
T |
13: 59,863,236 (GRCm39) |
H128L |
probably benign |
Het |
| Spdl1 |
A |
T |
11: 34,721,706 (GRCm39) |
M1K |
probably null |
Het |
| Tgm3 |
T |
A |
2: 129,868,697 (GRCm39) |
N211K |
probably benign |
Het |
| Tmem116 |
T |
C |
5: 121,606,050 (GRCm39) |
|
probably null |
Het |
| Tmem132e |
T |
A |
11: 82,329,212 (GRCm39) |
|
probably null |
Het |
| Tmem53 |
T |
C |
4: 117,125,705 (GRCm39) |
C251R |
probably damaging |
Het |
| Trcg1 |
A |
C |
9: 57,152,856 (GRCm39) |
D551A |
probably damaging |
Het |
| Trp63 |
T |
A |
16: 25,620,843 (GRCm39) |
F12I |
probably benign |
Het |
| Ttn |
C |
T |
2: 76,709,401 (GRCm39) |
|
probably null |
Het |
| Tubgcp4 |
T |
C |
2: 121,025,946 (GRCm39) |
V596A |
probably benign |
Het |
| Ugt2a3 |
A |
C |
5: 87,473,491 (GRCm39) |
H475Q |
probably damaging |
Het |
| Unc79 |
G |
A |
12: 103,025,759 (GRCm39) |
R382K |
probably damaging |
Het |
| Vmn2r58 |
T |
C |
7: 41,513,662 (GRCm39) |
H327R |
possibly damaging |
Het |
| Vmn2r7 |
G |
A |
3: 64,623,987 (GRCm39) |
T111I |
possibly damaging |
Het |
| Zfp318 |
T |
A |
17: 46,708,138 (GRCm39) |
Y399N |
probably damaging |
Het |
|
| Other mutations in Ift172 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Ift172
|
APN |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01399:Ift172
|
APN |
5 |
31,423,592 (GRCm39) |
missense |
probably benign |
|
|
IGL01405:Ift172
|
APN |
5 |
31,419,196 (GRCm39) |
nonsense |
probably null |
|
|
IGL01562:Ift172
|
APN |
5 |
31,424,591 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01758:Ift172
|
APN |
5 |
31,438,058 (GRCm39) |
missense |
probably benign |
|
|
IGL01792:Ift172
|
APN |
5 |
31,434,215 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01830:Ift172
|
APN |
5 |
31,442,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01839:Ift172
|
APN |
5 |
31,423,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02007:Ift172
|
APN |
5 |
31,443,948 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02172:Ift172
|
APN |
5 |
31,438,681 (GRCm39) |
splice site |
probably benign |
|
|
IGL02190:Ift172
|
APN |
5 |
31,411,802 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL02334:Ift172
|
APN |
5 |
31,440,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02486:Ift172
|
APN |
5 |
31,414,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02517:Ift172
|
APN |
5 |
31,410,992 (GRCm39) |
splice site |
probably null |
|
|
IGL02571:Ift172
|
APN |
5 |
31,415,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02626:Ift172
|
APN |
5 |
31,421,840 (GRCm39) |
missense |
probably benign |
|
|
IGL03183:Ift172
|
APN |
5 |
31,429,348 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL03277:Ift172
|
APN |
5 |
31,424,642 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03349:Ift172
|
APN |
5 |
31,441,474 (GRCm39) |
missense |
probably benign |
0.05 |
|
ostinato
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
pushback
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0042:Ift172
|
UTSW |
5 |
31,418,799 (GRCm39) |
missense |
probably benign |
0.35 |
|
PIT4802001:Ift172
|
UTSW |
5 |
31,442,610 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0153:Ift172
|
UTSW |
5 |
31,417,968 (GRCm39) |
missense |
probably benign |
|
|
R0328:Ift172
|
UTSW |
5 |
31,421,195 (GRCm39) |
nonsense |
probably null |
|
|
R0357:Ift172
|
UTSW |
5 |
31,415,244 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R0369:Ift172
|
UTSW |
5 |
31,410,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0391:Ift172
|
UTSW |
5 |
31,444,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0512:Ift172
|
UTSW |
5 |
31,442,821 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0546:Ift172
|
UTSW |
5 |
31,414,945 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0553:Ift172
|
UTSW |
5 |
31,433,186 (GRCm39) |
splice site |
probably benign |
|
|
R0606:Ift172
|
UTSW |
5 |
31,411,657 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0834:Ift172
|
UTSW |
5 |
31,414,715 (GRCm39) |
missense |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,415,262 (GRCm39) |
unclassified |
probably benign |
|
|
R0973:Ift172
|
UTSW |
5 |
31,422,699 (GRCm39) |
missense |
probably benign |
|
|
R1189:Ift172
|
UTSW |
5 |
31,443,174 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1205:Ift172
|
UTSW |
5 |
31,443,136 (GRCm39) |
missense |
probably benign |
|
|
R1289:Ift172
|
UTSW |
5 |
31,438,320 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1342:Ift172
|
UTSW |
5 |
31,419,210 (GRCm39) |
missense |
probably benign |
|
|
R1395:Ift172
|
UTSW |
5 |
31,442,582 (GRCm39) |
unclassified |
probably benign |
|
|
R1417:Ift172
|
UTSW |
5 |
31,413,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2020:Ift172
|
UTSW |
5 |
31,424,585 (GRCm39) |
nonsense |
probably null |
|
|
R2111:Ift172
|
UTSW |
5 |
31,443,423 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2175:Ift172
|
UTSW |
5 |
31,424,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2509:Ift172
|
UTSW |
5 |
31,420,312 (GRCm39) |
missense |
probably benign |
|
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2870:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2871:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2872:Ift172
|
UTSW |
5 |
31,415,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3705:Ift172
|
UTSW |
5 |
31,418,781 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3793:Ift172
|
UTSW |
5 |
31,414,925 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R4385:Ift172
|
UTSW |
5 |
31,444,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4477:Ift172
|
UTSW |
5 |
31,422,781 (GRCm39) |
missense |
probably benign |
0.38 |
|
R4590:Ift172
|
UTSW |
5 |
31,411,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4663:Ift172
|
UTSW |
5 |
31,441,559 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4665:Ift172
|
UTSW |
5 |
31,442,598 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4977:Ift172
|
UTSW |
5 |
31,429,460 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5109:Ift172
|
UTSW |
5 |
31,423,330 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5182:Ift172
|
UTSW |
5 |
31,424,958 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5343:Ift172
|
UTSW |
5 |
31,421,156 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5465:Ift172
|
UTSW |
5 |
31,418,862 (GRCm39) |
splice site |
probably null |
|
|
R5622:Ift172
|
UTSW |
5 |
31,440,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Ift172
|
UTSW |
5 |
31,412,621 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5793:Ift172
|
UTSW |
5 |
31,434,292 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R5870:Ift172
|
UTSW |
5 |
31,434,284 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5919:Ift172
|
UTSW |
5 |
31,418,006 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5968:Ift172
|
UTSW |
5 |
31,418,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6112:Ift172
|
UTSW |
5 |
31,414,241 (GRCm39) |
missense |
probably benign |
|
|
R6339:Ift172
|
UTSW |
5 |
31,444,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6339:Ift172
|
UTSW |
5 |
31,413,927 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6355:Ift172
|
UTSW |
5 |
31,441,501 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6565:Ift172
|
UTSW |
5 |
31,433,227 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6668:Ift172
|
UTSW |
5 |
31,412,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6755:Ift172
|
UTSW |
5 |
31,418,342 (GRCm39) |
nonsense |
probably null |
|
|
R6818:Ift172
|
UTSW |
5 |
31,423,304 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6939:Ift172
|
UTSW |
5 |
31,414,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7047:Ift172
|
UTSW |
5 |
31,433,238 (GRCm39) |
nonsense |
probably null |
|
|
R7156:Ift172
|
UTSW |
5 |
31,429,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Ift172
|
UTSW |
5 |
31,411,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Ift172
|
UTSW |
5 |
31,442,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7351:Ift172
|
UTSW |
5 |
31,433,240 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7706:Ift172
|
UTSW |
5 |
31,423,723 (GRCm39) |
nonsense |
probably null |
|
|
R7890:Ift172
|
UTSW |
5 |
31,440,425 (GRCm39) |
nonsense |
probably null |
|
|
R7980:Ift172
|
UTSW |
5 |
31,417,988 (GRCm39) |
missense |
probably benign |
|
|
R8263:Ift172
|
UTSW |
5 |
31,422,681 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8559:Ift172
|
UTSW |
5 |
31,413,921 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8717:Ift172
|
UTSW |
5 |
31,412,985 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8774:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R8774-TAIL:Ift172
|
UTSW |
5 |
31,415,207 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9037:Ift172
|
UTSW |
5 |
31,420,400 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9038:Ift172
|
UTSW |
5 |
31,441,399 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9133:Ift172
|
UTSW |
5 |
31,442,867 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9607:Ift172
|
UTSW |
5 |
31,410,913 (GRCm39) |
missense |
|
|
|
X0022:Ift172
|
UTSW |
5 |
31,442,664 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1176:Ift172
|
UTSW |
5 |
31,434,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTACCTCTTCAGGAATTTGGC -3'
(R):5'- ATATCCCACTGTGCAGGCTG -3'
Sequencing Primer
(F):5'- ATATATAGAGCTCAGCCTCTTGACC -3'
(R):5'- TCTGAACCTGGACCTTGTCAAAG -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation