Incidental Mutation 'R6994:Cfhr4'
| ID |
544014 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cfhr4
|
| Ensembl Gene |
ENSMUSG00000070594 |
| Gene Name |
complement factor H-related 4 |
| Synonyms |
Gm4788 |
| MMRRC Submission |
045100-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.063)
|
| Stock # |
R6994 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
139625657-139708977 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 139664668 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Leucine
at position 464
(I464L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107620
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027612]
[ENSMUST00000111986]
[ENSMUST00000111989]
|
| AlphaFold |
E9Q8B5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000027612
AA Change: I463L
PolyPhen 2
Score 0.037 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000027612
Gene: ENSMUSG00000070594
AA Change: I463L
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
28 |
88 |
1.65e-2 |
SMART |
|
CCP
|
92 |
145 |
1.15e-10 |
SMART |
|
CCP
|
151 |
208 |
5.65e-10 |
SMART |
|
CCP
|
212 |
267 |
1.12e-4 |
SMART |
|
CCP
|
272 |
325 |
4.52e-9 |
SMART |
|
CCP
|
332 |
386 |
9.1e-14 |
SMART |
|
CCP
|
393 |
446 |
1.58e-13 |
SMART |
|
CCP
|
455 |
505 |
4.92e-1 |
SMART |
|
CCP
|
511 |
564 |
8.9e-8 |
SMART |
|
CCP
|
569 |
622 |
4.18e-13 |
SMART |
|
CCP
|
627 |
681 |
3.5e-15 |
SMART |
|
CCP
|
688 |
742 |
5.69e-15 |
SMART |
|
CCP
|
746 |
807 |
2.77e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111986
AA Change: I464L
PolyPhen 2
Score 0.032 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000107617
Gene: ENSMUSG00000070594
AA Change: I464L
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
28 |
88 |
1.65e-2 |
SMART |
|
CCP
|
92 |
145 |
1.15e-10 |
SMART |
|
CCP
|
151 |
208 |
5.65e-10 |
SMART |
|
CCP
|
212 |
267 |
1.12e-4 |
SMART |
|
CCP
|
272 |
325 |
4.52e-9 |
SMART |
|
CCP
|
333 |
387 |
9.1e-14 |
SMART |
|
CCP
|
394 |
447 |
1.58e-13 |
SMART |
|
CCP
|
456 |
506 |
4.92e-1 |
SMART |
|
CCP
|
512 |
565 |
8.9e-8 |
SMART |
|
CCP
|
571 |
635 |
2.66e-6 |
SMART |
|
CCP
|
640 |
693 |
4.18e-13 |
SMART |
|
CCP
|
700 |
754 |
5.69e-15 |
SMART |
|
CCP
|
758 |
819 |
2.77e0 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000111989
AA Change: I464L
PolyPhen 2
Score 0.670 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000107620
Gene: ENSMUSG00000070594
AA Change: I464L
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
28 |
88 |
1.65e-2 |
SMART |
|
CCP
|
92 |
145 |
1.15e-10 |
SMART |
|
CCP
|
151 |
208 |
5.65e-10 |
SMART |
|
CCP
|
212 |
267 |
1.12e-4 |
SMART |
|
CCP
|
272 |
325 |
4.52e-9 |
SMART |
|
CCP
|
333 |
387 |
9.1e-14 |
SMART |
|
CCP
|
394 |
447 |
1.58e-13 |
SMART |
|
CCP
|
456 |
506 |
4.92e-1 |
SMART |
|
CCP
|
512 |
565 |
8.9e-8 |
SMART |
|
CCP
|
571 |
635 |
2.66e-6 |
SMART |
|
CCP
|
640 |
693 |
4.18e-13 |
SMART |
|
CCP
|
698 |
752 |
3.5e-15 |
SMART |
|
CCP
|
759 |
813 |
5.69e-15 |
SMART |
|
CCP
|
817 |
878 |
2.77e0 |
SMART |
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.8%
|
| Validation Efficiency |
96% (82/85) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl4 |
T |
G |
4: 144,349,849 (GRCm39) |
W369G |
probably damaging |
Het |
| Abhd16b |
C |
T |
2: 181,135,461 (GRCm39) |
T121M |
possibly damaging |
Het |
| Adam5 |
A |
T |
8: 25,276,262 (GRCm39) |
C468* |
probably null |
Het |
| Aim2 |
C |
T |
1: 173,283,152 (GRCm39) |
A78V |
possibly damaging |
Het |
| Alg9 |
G |
A |
9: 50,703,422 (GRCm39) |
W254* |
probably null |
Het |
| Ankrd55 |
G |
C |
13: 112,504,834 (GRCm39) |
E499Q |
probably benign |
Het |
| Atp6v0a2 |
T |
C |
5: 124,791,209 (GRCm39) |
F546S |
probably damaging |
Het |
| Bean1 |
CT |
C |
8: 104,908,664 (GRCm39) |
|
probably null |
Het |
| Bpi |
A |
T |
2: 158,100,164 (GRCm39) |
|
probably benign |
Het |
| Bves |
A |
G |
10: 45,215,514 (GRCm39) |
H63R |
probably benign |
Het |
| Ccdc183 |
T |
C |
2: 25,507,057 (GRCm39) |
M45V |
probably benign |
Het |
| Cmklr1 |
T |
C |
5: 113,752,983 (GRCm39) |
Y6C |
probably damaging |
Het |
| Colgalt1 |
C |
T |
8: 72,076,165 (GRCm39) |
R539C |
probably damaging |
Het |
| Ctsm |
T |
A |
13: 61,687,698 (GRCm39) |
E53D |
probably damaging |
Het |
| Cyp2a22 |
A |
G |
7: 26,638,606 (GRCm39) |
|
probably null |
Het |
| Ddx10 |
A |
G |
9: 53,115,411 (GRCm39) |
V641A |
probably damaging |
Het |
| Ddx6 |
T |
C |
9: 44,540,020 (GRCm39) |
V316A |
probably damaging |
Het |
| Dhx34 |
T |
C |
7: 15,937,799 (GRCm39) |
D767G |
probably benign |
Het |
| Dnaaf6rt |
T |
C |
1: 31,261,990 (GRCm39) |
|
probably benign |
Het |
| Dtnbp1 |
T |
A |
13: 45,155,405 (GRCm39) |
D15V |
probably damaging |
Het |
| Dtx3l |
C |
T |
16: 35,751,742 (GRCm39) |
|
probably null |
Het |
| Entpd8 |
T |
C |
2: 24,973,321 (GRCm39) |
I162T |
probably damaging |
Het |
| Fam186a |
G |
T |
15: 99,840,347 (GRCm39) |
Q1966K |
probably benign |
Het |
| Fbxo27 |
A |
C |
7: 28,392,785 (GRCm39) |
D22A |
probably damaging |
Het |
| Fermt3 |
A |
T |
19: 6,977,095 (GRCm39) |
I577N |
probably damaging |
Het |
| Frmd8 |
A |
T |
19: 5,923,209 (GRCm39) |
S81T |
probably damaging |
Het |
| Gm5108 |
T |
A |
5: 68,102,012 (GRCm39) |
|
probably benign |
Het |
| Gm9195 |
T |
C |
14: 72,718,271 (GRCm39) |
Y135C |
probably damaging |
Het |
| Gpatch2l |
G |
A |
12: 86,290,958 (GRCm39) |
R47H |
probably damaging |
Het |
| Kcnh8 |
A |
T |
17: 53,284,723 (GRCm39) |
I898F |
probably benign |
Het |
| Kri1 |
C |
T |
9: 21,199,083 (GRCm39) |
|
probably benign |
Het |
| Krt32 |
T |
A |
11: 99,977,271 (GRCm39) |
I210F |
probably damaging |
Het |
| Lama1 |
G |
A |
17: 68,060,820 (GRCm39) |
C716Y |
|
Het |
| Lamc2 |
G |
A |
1: 153,012,508 (GRCm39) |
T722M |
probably benign |
Het |
| Lpin3 |
C |
T |
2: 160,746,803 (GRCm39) |
P766L |
probably damaging |
Het |
| Macroh2a1 |
T |
C |
13: 56,237,643 (GRCm39) |
N206D |
probably benign |
Het |
| Marf1 |
T |
C |
16: 13,946,721 (GRCm39) |
T1169A |
probably damaging |
Het |
| Morc1 |
G |
A |
16: 48,385,984 (GRCm39) |
V536M |
probably benign |
Het |
| Morc1 |
A |
T |
16: 48,438,909 (GRCm39) |
H768L |
probably benign |
Het |
| Mpped2 |
T |
A |
2: 106,529,878 (GRCm39) |
H42Q |
possibly damaging |
Het |
| Nfatc1 |
G |
T |
18: 80,696,779 (GRCm39) |
|
probably null |
Het |
| Nfkbid |
G |
A |
7: 30,125,192 (GRCm39) |
S263N |
probably benign |
Het |
| Npas3 |
C |
A |
12: 54,115,576 (GRCm39) |
Q802K |
probably damaging |
Het |
| Or52s1b |
T |
C |
7: 102,822,119 (GRCm39) |
T242A |
probably damaging |
Het |
| Or5ac20 |
T |
G |
16: 59,104,453 (GRCm39) |
M136L |
possibly damaging |
Het |
| Or5p67 |
T |
A |
7: 107,922,101 (GRCm39) |
I261F |
possibly damaging |
Het |
| Pabpc4l |
C |
A |
3: 46,401,345 (GRCm39) |
V100L |
possibly damaging |
Het |
| Pagr1a |
A |
G |
7: 126,615,613 (GRCm39) |
|
probably null |
Het |
| Pcdh1 |
A |
T |
18: 38,331,553 (GRCm39) |
N483K |
probably damaging |
Het |
| Pikfyve |
C |
A |
1: 65,291,689 (GRCm39) |
P1303T |
probably damaging |
Het |
| Plekhh3 |
T |
A |
11: 101,056,519 (GRCm39) |
|
probably null |
Het |
| Pnkd |
T |
A |
1: 74,332,335 (GRCm39) |
|
probably null |
Het |
| Pparg |
A |
T |
6: 115,428,011 (GRCm39) |
Q166L |
probably benign |
Het |
| Psenen |
A |
G |
7: 30,262,932 (GRCm39) |
|
probably null |
Het |
| Rab4a |
T |
C |
8: 124,557,105 (GRCm39) |
S142P |
probably damaging |
Het |
| Reg3a |
T |
C |
6: 78,358,132 (GRCm39) |
V21A |
probably benign |
Het |
| Relt |
A |
C |
7: 100,502,321 (GRCm39) |
|
probably benign |
Het |
| Rftn1 |
T |
A |
17: 50,344,019 (GRCm39) |
T90S |
possibly damaging |
Het |
| Ripor3 |
T |
G |
2: 167,839,186 (GRCm39) |
D105A |
probably damaging |
Het |
| Rnase10 |
T |
A |
14: 51,247,138 (GRCm39) |
I135N |
probably damaging |
Het |
| Rsrc1 |
C |
T |
3: 66,901,982 (GRCm39) |
P44L |
unknown |
Het |
| Rttn |
A |
G |
18: 89,047,023 (GRCm39) |
E895G |
probably damaging |
Het |
| Serpina3a |
G |
A |
12: 104,079,089 (GRCm39) |
|
probably null |
Het |
| Slco5a1 |
C |
T |
1: 12,951,617 (GRCm39) |
C562Y |
probably damaging |
Het |
| Spen |
T |
C |
4: 141,220,770 (GRCm39) |
T396A |
unknown |
Het |
| Tgfbr3 |
A |
G |
5: 107,280,892 (GRCm39) |
S623P |
probably damaging |
Het |
| Tmem8b |
A |
G |
4: 43,690,192 (GRCm39) |
I876V |
probably damaging |
Het |
| Tmod3 |
T |
C |
9: 75,416,669 (GRCm39) |
K221R |
probably damaging |
Het |
| Tomm40 |
G |
T |
7: 19,436,831 (GRCm39) |
D40E |
probably damaging |
Het |
| Trav6d-4 |
G |
T |
14: 52,991,048 (GRCm39) |
G28V |
probably damaging |
Het |
| Trav8d-2 |
G |
T |
14: 53,279,933 (GRCm39) |
A17S |
probably benign |
Het |
| Triml2 |
T |
C |
8: 43,643,115 (GRCm39) |
C158R |
possibly damaging |
Het |
| Trip10 |
A |
G |
17: 57,562,331 (GRCm39) |
E283G |
probably damaging |
Het |
| Tubb2b |
T |
C |
13: 34,311,518 (GRCm39) |
Y425C |
probably damaging |
Het |
| Ubr1 |
T |
C |
2: 120,794,074 (GRCm39) |
T37A |
probably benign |
Het |
| Unc13b |
A |
G |
4: 43,171,403 (GRCm39) |
|
probably benign |
Het |
| Unc13b |
A |
G |
4: 43,173,203 (GRCm39) |
|
probably benign |
Het |
| Vcan |
A |
T |
13: 89,841,526 (GRCm39) |
D379E |
possibly damaging |
Het |
| Vmn1r44 |
T |
A |
6: 89,871,140 (GRCm39) |
H295Q |
probably benign |
Het |
| Vmn2r16 |
A |
T |
5: 109,487,969 (GRCm39) |
S281C |
probably damaging |
Het |
| Vmn2r84 |
C |
T |
10: 130,226,876 (GRCm39) |
A321T |
possibly damaging |
Het |
| Vsig10l |
A |
T |
7: 43,114,491 (GRCm39) |
H271L |
possibly damaging |
Het |
| Vwa8 |
A |
T |
14: 79,145,596 (GRCm39) |
H91L |
possibly damaging |
Het |
| Zfp957 |
T |
A |
14: 79,451,130 (GRCm39) |
E223V |
probably damaging |
Het |
|
| Other mutations in Cfhr4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00906:Cfhr4
|
APN |
1 |
139,659,312 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01088:Cfhr4
|
APN |
1 |
139,625,823 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01419:Cfhr4
|
APN |
1 |
139,667,382 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01552:Cfhr4
|
APN |
1 |
139,667,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01924:Cfhr4
|
APN |
1 |
139,666,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02032:Cfhr4
|
APN |
1 |
139,702,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02254:Cfhr4
|
APN |
1 |
139,661,143 (GRCm39) |
splice site |
probably benign |
|
|
IGL02318:Cfhr4
|
APN |
1 |
139,708,835 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL02527:Cfhr4
|
APN |
1 |
139,680,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02531:Cfhr4
|
APN |
1 |
139,702,307 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL02587:Cfhr4
|
APN |
1 |
139,629,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02644:Cfhr4
|
APN |
1 |
139,708,905 (GRCm39) |
start codon destroyed |
probably null |
0.63 |
|
IGL02852:Cfhr4
|
APN |
1 |
139,701,754 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02963:Cfhr4
|
APN |
1 |
139,659,334 (GRCm39) |
nonsense |
probably null |
|
|
IGL03084:Cfhr4
|
APN |
1 |
139,708,880 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0131:Cfhr4
|
UTSW |
1 |
139,682,009 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0131:Cfhr4
|
UTSW |
1 |
139,682,009 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0132:Cfhr4
|
UTSW |
1 |
139,682,009 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0549:Cfhr4
|
UTSW |
1 |
139,667,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0558:Cfhr4
|
UTSW |
1 |
139,667,230 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0610:Cfhr4
|
UTSW |
1 |
139,629,584 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1341:Cfhr4
|
UTSW |
1 |
139,660,131 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1460:Cfhr4
|
UTSW |
1 |
139,625,934 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Cfhr4
|
UTSW |
1 |
139,664,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Cfhr4
|
UTSW |
1 |
139,702,398 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2032:Cfhr4
|
UTSW |
1 |
139,660,993 (GRCm39) |
splice site |
probably benign |
|
|
R2111:Cfhr4
|
UTSW |
1 |
139,702,417 (GRCm39) |
splice site |
probably benign |
|
|
R2179:Cfhr4
|
UTSW |
1 |
139,659,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3806:Cfhr4
|
UTSW |
1 |
139,680,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4356:Cfhr4
|
UTSW |
1 |
139,660,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4747:Cfhr4
|
UTSW |
1 |
139,625,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4838:Cfhr4
|
UTSW |
1 |
139,661,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4867:Cfhr4
|
UTSW |
1 |
139,702,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4910:Cfhr4
|
UTSW |
1 |
139,702,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4911:Cfhr4
|
UTSW |
1 |
139,702,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5050:Cfhr4
|
UTSW |
1 |
139,664,578 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5120:Cfhr4
|
UTSW |
1 |
139,680,841 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5259:Cfhr4
|
UTSW |
1 |
139,668,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5504:Cfhr4
|
UTSW |
1 |
139,629,558 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5825:Cfhr4
|
UTSW |
1 |
139,702,336 (GRCm39) |
splice site |
probably null |
|
|
R5949:Cfhr4
|
UTSW |
1 |
139,660,887 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6140:Cfhr4
|
UTSW |
1 |
139,660,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6200:Cfhr4
|
UTSW |
1 |
139,682,073 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6254:Cfhr4
|
UTSW |
1 |
139,682,128 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6255:Cfhr4
|
UTSW |
1 |
139,680,749 (GRCm39) |
nonsense |
probably null |
|
|
R6334:Cfhr4
|
UTSW |
1 |
139,701,662 (GRCm39) |
splice site |
probably null |
|
|
R6611:Cfhr4
|
UTSW |
1 |
139,660,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6798:Cfhr4
|
UTSW |
1 |
139,625,859 (GRCm39) |
missense |
probably benign |
0.20 |
|
R6800:Cfhr4
|
UTSW |
1 |
139,629,719 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6895:Cfhr4
|
UTSW |
1 |
139,668,210 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6904:Cfhr4
|
UTSW |
1 |
139,659,391 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7173:Cfhr4
|
UTSW |
1 |
139,659,415 (GRCm39) |
nonsense |
probably null |
|
|
R7184:Cfhr4
|
UTSW |
1 |
139,660,822 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7192:Cfhr4
|
UTSW |
1 |
139,667,033 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7205:Cfhr4
|
UTSW |
1 |
139,680,788 (GRCm39) |
nonsense |
probably null |
|
|
R7302:Cfhr4
|
UTSW |
1 |
139,667,436 (GRCm39) |
splice site |
probably null |
|
|
R7308:Cfhr4
|
UTSW |
1 |
139,682,041 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7735:Cfhr4
|
UTSW |
1 |
139,660,039 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8006:Cfhr4
|
UTSW |
1 |
139,664,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8045:Cfhr4
|
UTSW |
1 |
139,661,243 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8188:Cfhr4
|
UTSW |
1 |
139,625,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8339:Cfhr4
|
UTSW |
1 |
139,660,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9156:Cfhr4
|
UTSW |
1 |
139,660,085 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9339:Cfhr4
|
UTSW |
1 |
139,682,044 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9520:Cfhr4
|
UTSW |
1 |
139,682,135 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9525:Cfhr4
|
UTSW |
1 |
139,702,250 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9554:Cfhr4
|
UTSW |
1 |
139,668,169 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9635:Cfhr4
|
UTSW |
1 |
139,701,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9669:Cfhr4
|
UTSW |
1 |
139,708,872 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9737:Cfhr4
|
UTSW |
1 |
139,708,872 (GRCm39) |
missense |
probably damaging |
0.96 |
|
X0009:Cfhr4
|
UTSW |
1 |
139,661,287 (GRCm39) |
missense |
probably benign |
0.08 |
|
X0024:Cfhr4
|
UTSW |
1 |
139,661,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Cfhr4
|
UTSW |
1 |
139,681,999 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Cfhr4
|
UTSW |
1 |
139,661,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Cfhr4
|
UTSW |
1 |
139,625,994 (GRCm39) |
missense |
probably benign |
0.13 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAATGCTAGGACACTCAGACAG -3'
(R):5'- TGGACATGATATCCCATTTCCAC -3'
Sequencing Primer
(F):5'- ACTCAGACAGTGCCAATAAGC -3'
(R):5'- TCTGCACGGTGAATCTCAG -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation