Incidental Mutation 'R7017:Cacna1i'
| ID |
545407 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cacna1i
|
| Ensembl Gene |
ENSMUSG00000022416 |
| Gene Name |
calcium channel, voltage-dependent, alpha 1I subunit |
| Synonyms |
|
| MMRRC Submission |
045118-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7017 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
80171439-80282480 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 80264671 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 1500
(F1500L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125229
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000160424]
[ENSMUST00000162155]
|
| AlphaFold |
E9Q7P2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160424
AA Change: F1500L
PolyPhen 2
Score 0.423 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000125063
Gene: ENSMUSG00000022416
AA Change: F1500L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
16 |
N/A |
INTRINSIC |
|
low complexity region
|
24 |
40 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
76 |
407 |
1.4e-79 |
PFAM |
|
low complexity region
|
464 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
531 |
554 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
597 |
830 |
7.4e-58 |
PFAM |
|
low complexity region
|
870 |
892 |
N/A |
INTRINSIC |
|
low complexity region
|
919 |
940 |
N/A |
INTRINSIC |
|
low complexity region
|
984 |
1015 |
N/A |
INTRINSIC |
|
low complexity region
|
1069 |
1080 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
1128 |
1401 |
7.8e-65 |
PFAM |
|
Pfam:Ion_trans
|
1445 |
1700 |
9.4e-58 |
PFAM |
|
Pfam:PKD_channel
|
1538 |
1694 |
1.4e-10 |
PFAM |
|
low complexity region
|
1718 |
1739 |
N/A |
INTRINSIC |
|
low complexity region
|
1744 |
1760 |
N/A |
INTRINSIC |
|
low complexity region
|
1837 |
1853 |
N/A |
INTRINSIC |
|
low complexity region
|
1922 |
1933 |
N/A |
INTRINSIC |
|
low complexity region
|
1990 |
2005 |
N/A |
INTRINSIC |
|
low complexity region
|
2041 |
2058 |
N/A |
INTRINSIC |
|
low complexity region
|
2087 |
2097 |
N/A |
INTRINSIC |
|
low complexity region
|
2103 |
2126 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000162155
AA Change: F1500L
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000125229
Gene: ENSMUSG00000022416
AA Change: F1500L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
16 |
N/A |
INTRINSIC |
|
low complexity region
|
24 |
40 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
115 |
395 |
1.9e-66 |
PFAM |
|
low complexity region
|
464 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
531 |
554 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
632 |
819 |
2.4e-45 |
PFAM |
|
low complexity region
|
870 |
892 |
N/A |
INTRINSIC |
|
low complexity region
|
919 |
940 |
N/A |
INTRINSIC |
|
low complexity region
|
984 |
1015 |
N/A |
INTRINSIC |
|
low complexity region
|
1069 |
1080 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
1165 |
1389 |
6.2e-55 |
PFAM |
|
coiled coil region
|
1394 |
1426 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
1480 |
1688 |
1.9e-47 |
PFAM |
|
Pfam:PKD_channel
|
1538 |
1694 |
4.8e-10 |
PFAM |
|
low complexity region
|
1718 |
1739 |
N/A |
INTRINSIC |
|
low complexity region
|
1744 |
1760 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.5%
|
| Validation Efficiency |
100% (75/75) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2410137M14Rik |
A |
G |
17: 37,288,926 (GRCm39) |
|
probably benign |
Het |
| Acot3 |
A |
T |
12: 84,100,077 (GRCm39) |
|
probably benign |
Het |
| Add3 |
T |
A |
19: 53,222,284 (GRCm39) |
V297E |
possibly damaging |
Het |
| Arfgap1 |
C |
G |
2: 180,618,097 (GRCm39) |
|
probably null |
Het |
| Cacna1s |
T |
C |
1: 136,023,596 (GRCm39) |
I945T |
probably damaging |
Het |
| Ccdc180 |
T |
A |
4: 45,940,934 (GRCm39) |
N1334K |
possibly damaging |
Het |
| Cd5l |
C |
A |
3: 87,273,368 (GRCm39) |
Y112* |
probably null |
Het |
| Cracd |
GAGGCAGCGCGAGGCCGAGAGGCAGGAGGAGGAAGCAAGACAACGCGAGGCCGAGAGGCAGG |
GAGACAACGCGAGGCCGAGAGGCAGG |
5: 77,004,795 (GRCm39) |
|
probably benign |
Het |
| Cyp2d40 |
A |
T |
15: 82,644,234 (GRCm39) |
F297Y |
unknown |
Het |
| Ddx4 |
C |
T |
13: 112,738,022 (GRCm39) |
V546I |
probably damaging |
Het |
| Dgkg |
T |
C |
16: 22,391,463 (GRCm39) |
M332V |
probably benign |
Het |
| Dnah12 |
T |
C |
14: 26,456,835 (GRCm39) |
I867T |
probably benign |
Het |
| Dnah2 |
T |
A |
11: 69,382,373 (GRCm39) |
K1246* |
probably null |
Het |
| Drd2 |
G |
A |
9: 49,312,129 (GRCm39) |
V161I |
probably benign |
Het |
| Dsp |
A |
G |
13: 38,370,683 (GRCm39) |
D862G |
probably benign |
Het |
| Ephx4 |
T |
C |
5: 107,553,980 (GRCm39) |
F10S |
probably damaging |
Het |
| Fabp9 |
C |
A |
3: 10,259,756 (GRCm39) |
A76S |
possibly damaging |
Het |
| Fat4 |
G |
A |
3: 38,945,692 (GRCm39) |
M1528I |
probably benign |
Het |
| Fbxl12 |
A |
G |
9: 20,529,616 (GRCm39) |
S84P |
unknown |
Het |
| Fbxo40 |
T |
C |
16: 36,790,732 (GRCm39) |
D126G |
probably damaging |
Het |
| Fpr1 |
C |
T |
17: 18,097,654 (GRCm39) |
V112I |
probably benign |
Het |
| Frem2 |
T |
C |
3: 53,427,023 (GRCm39) |
N2975S |
probably benign |
Het |
| Gask1a |
T |
C |
9: 121,795,052 (GRCm39) |
|
probably null |
Het |
| Gm7945 |
T |
C |
14: 41,105,610 (GRCm39) |
Y156C |
|
Het |
| Gnpat |
T |
C |
8: 125,590,014 (GRCm39) |
V13A |
probably benign |
Het |
| Gpx5 |
G |
A |
13: 21,475,561 (GRCm39) |
P55L |
probably damaging |
Het |
| Hbp1 |
A |
G |
12: 31,993,852 (GRCm39) |
S59P |
probably damaging |
Het |
| Ighv1-36 |
T |
A |
12: 114,843,533 (GRCm39) |
D109V |
probably damaging |
Het |
| Iqcf5 |
T |
A |
9: 106,392,863 (GRCm39) |
I40N |
possibly damaging |
Het |
| Kcnma1 |
T |
G |
14: 23,544,711 (GRCm39) |
I484L |
possibly damaging |
Het |
| Kera |
A |
T |
10: 97,444,939 (GRCm39) |
R99S |
possibly damaging |
Het |
| Kif3b |
T |
A |
2: 153,171,644 (GRCm39) |
S707R |
possibly damaging |
Het |
| Lilra6 |
G |
T |
7: 3,911,707 (GRCm39) |
T317N |
possibly damaging |
Het |
| Lrrc15 |
C |
T |
16: 30,091,780 (GRCm39) |
E520K |
probably benign |
Het |
| Lrrc34 |
C |
T |
3: 30,699,465 (GRCm39) |
|
probably null |
Het |
| Lvrn |
A |
G |
18: 46,983,745 (GRCm39) |
T163A |
probably benign |
Het |
| Met |
T |
A |
6: 17,491,286 (GRCm39) |
L16* |
probably null |
Het |
| Mpzl2 |
G |
T |
9: 44,958,587 (GRCm39) |
D108Y |
probably benign |
Het |
| Mrgprb2 |
T |
A |
7: 48,202,585 (GRCm39) |
I47F |
probably benign |
Het |
| Muc5ac |
G |
C |
7: 141,363,424 (GRCm39) |
|
probably benign |
Het |
| Mybphl |
T |
A |
3: 108,282,154 (GRCm39) |
V128E |
probably damaging |
Het |
| Nckap5 |
A |
T |
1: 126,030,398 (GRCm39) |
D231E |
probably damaging |
Het |
| Or5g23 |
T |
A |
2: 85,438,673 (GRCm39) |
M194L |
probably benign |
Het |
| Orm1 |
T |
A |
4: 63,263,448 (GRCm39) |
I87K |
probably benign |
Het |
| Pdgfrb |
C |
T |
18: 61,214,076 (GRCm39) |
P954S |
probably benign |
Het |
| Pdzd8 |
G |
T |
19: 59,333,784 (GRCm39) |
S79* |
probably null |
Het |
| Pdzd9 |
T |
A |
7: 120,262,225 (GRCm39) |
H79L |
probably benign |
Het |
| Plcg1 |
A |
T |
2: 160,600,017 (GRCm39) |
I926F |
probably damaging |
Het |
| Plec |
A |
T |
15: 76,057,741 (GRCm39) |
F4078L |
probably damaging |
Het |
| Plek |
G |
A |
11: 17,002,220 (GRCm39) |
|
probably benign |
Het |
| Pogz |
T |
C |
3: 94,761,335 (GRCm39) |
I25T |
probably damaging |
Het |
| Ppfia3 |
A |
T |
7: 45,008,224 (GRCm39) |
D215E |
probably benign |
Het |
| Psg22 |
C |
A |
7: 18,458,366 (GRCm39) |
S352R |
probably benign |
Het |
| Ptchd4 |
A |
G |
17: 42,813,626 (GRCm39) |
Y509C |
probably damaging |
Het |
| Ralgapb |
C |
A |
2: 158,290,257 (GRCm39) |
N389K |
probably benign |
Het |
| Rdh1 |
A |
G |
10: 127,598,906 (GRCm39) |
D129G |
probably benign |
Het |
| Rimbp3 |
A |
G |
16: 17,027,610 (GRCm39) |
T345A |
probably benign |
Het |
| S100a14 |
T |
C |
3: 90,434,602 (GRCm39) |
|
probably null |
Het |
| Scamp1 |
T |
A |
13: 94,361,423 (GRCm39) |
R152S |
probably damaging |
Het |
| Slc30a2 |
G |
A |
4: 134,074,726 (GRCm39) |
R161Q |
probably damaging |
Het |
| Srf |
T |
C |
17: 46,861,830 (GRCm39) |
T383A |
probably benign |
Het |
| St6galnac5 |
T |
C |
3: 152,552,040 (GRCm39) |
M176V |
probably damaging |
Het |
| St8sia1 |
C |
A |
6: 142,813,632 (GRCm39) |
V177F |
probably damaging |
Het |
| Syt12 |
C |
T |
19: 4,510,895 (GRCm39) |
|
probably null |
Het |
| Tanc2 |
A |
G |
11: 105,813,934 (GRCm39) |
I1793V |
probably benign |
Het |
| Tas2r123 |
A |
G |
6: 132,824,513 (GRCm39) |
I137V |
probably benign |
Het |
| Tenm2 |
T |
A |
11: 36,062,236 (GRCm39) |
Y543F |
probably damaging |
Het |
| Tent5b |
T |
C |
4: 133,213,545 (GRCm39) |
S139P |
possibly damaging |
Het |
| Tgfbr1 |
T |
C |
4: 47,410,728 (GRCm39) |
I488T |
probably damaging |
Het |
| Tgm1 |
T |
A |
14: 55,942,398 (GRCm39) |
Y651F |
possibly damaging |
Het |
| Thbs3 |
A |
T |
3: 89,131,722 (GRCm39) |
D698V |
probably damaging |
Het |
| Tpra1 |
T |
A |
6: 88,885,294 (GRCm39) |
I82N |
probably damaging |
Het |
| Ubr4 |
T |
A |
4: 139,120,401 (GRCm39) |
D275E |
probably damaging |
Het |
| Vmn2r111 |
T |
C |
17: 22,778,032 (GRCm39) |
N549S |
possibly damaging |
Het |
| Wwp1 |
T |
C |
4: 19,623,124 (GRCm39) |
Y787C |
probably damaging |
Het |
| Znfx1 |
T |
C |
2: 166,890,454 (GRCm39) |
S677G |
probably damaging |
Het |
|
| Other mutations in Cacna1i |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00421:Cacna1i
|
APN |
15 |
80,266,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00976:Cacna1i
|
APN |
15 |
80,239,846 (GRCm39) |
missense |
probably benign |
|
|
IGL01338:Cacna1i
|
APN |
15 |
80,232,581 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01589:Cacna1i
|
APN |
15 |
80,271,960 (GRCm39) |
splice site |
probably benign |
|
|
IGL01669:Cacna1i
|
APN |
15 |
80,275,958 (GRCm39) |
missense |
probably benign |
|
|
IGL01807:Cacna1i
|
APN |
15 |
80,258,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01911:Cacna1i
|
APN |
15 |
80,275,933 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01973:Cacna1i
|
APN |
15 |
80,266,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02205:Cacna1i
|
APN |
15 |
80,257,152 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02519:Cacna1i
|
APN |
15 |
80,246,075 (GRCm39) |
nonsense |
probably null |
|
|
IGL02648:Cacna1i
|
APN |
15 |
80,182,839 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03033:Cacna1i
|
APN |
15 |
80,246,440 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03214:Cacna1i
|
APN |
15 |
80,239,917 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0067:Cacna1i
|
UTSW |
15 |
80,265,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0067:Cacna1i
|
UTSW |
15 |
80,265,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0295:Cacna1i
|
UTSW |
15 |
80,240,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0345:Cacna1i
|
UTSW |
15 |
80,256,663 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0415:Cacna1i
|
UTSW |
15 |
80,253,031 (GRCm39) |
splice site |
probably benign |
|
|
R0637:Cacna1i
|
UTSW |
15 |
80,256,855 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0638:Cacna1i
|
UTSW |
15 |
80,265,281 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0840:Cacna1i
|
UTSW |
15 |
80,243,150 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1463:Cacna1i
|
UTSW |
15 |
80,263,255 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1528:Cacna1i
|
UTSW |
15 |
80,275,975 (GRCm39) |
splice site |
probably null |
|
|
R1563:Cacna1i
|
UTSW |
15 |
80,274,056 (GRCm39) |
splice site |
probably benign |
|
|
R1563:Cacna1i
|
UTSW |
15 |
80,205,389 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1573:Cacna1i
|
UTSW |
15 |
80,277,869 (GRCm39) |
splice site |
probably null |
|
|
R1654:Cacna1i
|
UTSW |
15 |
80,273,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Cacna1i
|
UTSW |
15 |
80,255,730 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1794:Cacna1i
|
UTSW |
15 |
80,273,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1824:Cacna1i
|
UTSW |
15 |
80,260,990 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1863:Cacna1i
|
UTSW |
15 |
80,243,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1885:Cacna1i
|
UTSW |
15 |
80,243,145 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1886:Cacna1i
|
UTSW |
15 |
80,243,145 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1899:Cacna1i
|
UTSW |
15 |
80,275,843 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1907:Cacna1i
|
UTSW |
15 |
80,259,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1943:Cacna1i
|
UTSW |
15 |
80,279,245 (GRCm39) |
missense |
probably benign |
|
|
R2162:Cacna1i
|
UTSW |
15 |
80,240,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2888:Cacna1i
|
UTSW |
15 |
80,258,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3701:Cacna1i
|
UTSW |
15 |
80,265,272 (GRCm39) |
splice site |
probably benign |
|
|
R3702:Cacna1i
|
UTSW |
15 |
80,265,272 (GRCm39) |
splice site |
probably benign |
|
|
R3832:Cacna1i
|
UTSW |
15 |
80,240,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4852:Cacna1i
|
UTSW |
15 |
80,272,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4857:Cacna1i
|
UTSW |
15 |
80,253,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4950:Cacna1i
|
UTSW |
15 |
80,252,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4980:Cacna1i
|
UTSW |
15 |
80,232,650 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5217:Cacna1i
|
UTSW |
15 |
80,275,041 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5437:Cacna1i
|
UTSW |
15 |
80,255,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5519:Cacna1i
|
UTSW |
15 |
80,255,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5642:Cacna1i
|
UTSW |
15 |
80,279,279 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R6217:Cacna1i
|
UTSW |
15 |
80,273,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6225:Cacna1i
|
UTSW |
15 |
80,205,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6251:Cacna1i
|
UTSW |
15 |
80,220,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6463:Cacna1i
|
UTSW |
15 |
80,239,959 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6490:Cacna1i
|
UTSW |
15 |
80,262,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6613:Cacna1i
|
UTSW |
15 |
80,205,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6884:Cacna1i
|
UTSW |
15 |
80,259,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6904:Cacna1i
|
UTSW |
15 |
80,259,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7155:Cacna1i
|
UTSW |
15 |
80,279,439 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7274:Cacna1i
|
UTSW |
15 |
80,261,023 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7323:Cacna1i
|
UTSW |
15 |
80,275,854 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7335:Cacna1i
|
UTSW |
15 |
80,259,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7571:Cacna1i
|
UTSW |
15 |
80,259,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7768:Cacna1i
|
UTSW |
15 |
80,265,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7820:Cacna1i
|
UTSW |
15 |
80,256,573 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7987:Cacna1i
|
UTSW |
15 |
80,204,553 (GRCm39) |
splice site |
probably null |
|
|
R8150:Cacna1i
|
UTSW |
15 |
80,259,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8206:Cacna1i
|
UTSW |
15 |
80,274,016 (GRCm39) |
splice site |
probably null |
|
|
R8270:Cacna1i
|
UTSW |
15 |
80,257,835 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8382:Cacna1i
|
UTSW |
15 |
80,261,017 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8501:Cacna1i
|
UTSW |
15 |
80,266,247 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8518:Cacna1i
|
UTSW |
15 |
80,243,095 (GRCm39) |
nonsense |
probably null |
|
|
R8552:Cacna1i
|
UTSW |
15 |
80,204,598 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R8679:Cacna1i
|
UTSW |
15 |
80,260,011 (GRCm39) |
intron |
probably benign |
|
|
R8696:Cacna1i
|
UTSW |
15 |
80,266,175 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8887:Cacna1i
|
UTSW |
15 |
80,258,894 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9274:Cacna1i
|
UTSW |
15 |
80,254,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9379:Cacna1i
|
UTSW |
15 |
80,259,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9508:Cacna1i
|
UTSW |
15 |
80,279,372 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9518:Cacna1i
|
UTSW |
15 |
80,271,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9674:Cacna1i
|
UTSW |
15 |
80,264,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9747:Cacna1i
|
UTSW |
15 |
80,246,318 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9769:Cacna1i
|
UTSW |
15 |
80,253,793 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0022:Cacna1i
|
UTSW |
15 |
80,246,163 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0024:Cacna1i
|
UTSW |
15 |
80,246,340 (GRCm39) |
missense |
probably benign |
0.03 |
|
X0058:Cacna1i
|
UTSW |
15 |
80,263,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Cacna1i
|
UTSW |
15 |
80,273,584 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Z1177:Cacna1i
|
UTSW |
15 |
80,265,380 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAGGCTAGCACAGATGAGG -3'
(R):5'- ATCCATTCACTGTGACTTAATCGC -3'
Sequencing Primer
(F):5'- AGCGATGTGAAATGACTTAACAC -3'
(R):5'- CCTCTTGTCTGGGAATGTAGTCAAC -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation