Mutagenetix > Incidental Mutation

Incidental Mutation 'R7022:Dnhd1'

545693

Institutional Source

Beutler Lab

Gene Symbol

Dnhd1

Ensembl Gene

ENSMUSG00000030882

Gene Name

dynein heavy chain domain 1

Synonyms

8030491N06Rik

MMRRC Submission

045123-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.090) question?

Stock #

R7022 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

105300034-105371006 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 105370005 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Proline to Serine at position 4477 (P4477S)

Ref Sequence

ENSEMBL: ENSMUSP00000121261 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000145988]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000145988
AA Change: P4477S

PolyPhen 2 Score 0.357 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000121261
Gene: ENSMUSG00000030882
AA Change: P4477S

Domain	Start	End	E-Value	Type
low complexity region	5	18	N/A	INTRINSIC
low complexity region	102	115	N/A	INTRINSIC
low complexity region	183	191	N/A	INTRINSIC
low complexity region	253	269	N/A	INTRINSIC
low complexity region	943	962	N/A	INTRINSIC
Pfam:DHC_N2	1018	1472	4.6e-50	PFAM
Pfam:AAA_6	1652	1875	2.7e-14	PFAM
low complexity region	1906	1918	N/A	INTRINSIC
Blast:AAA	1993	2196	1e-34	BLAST
Pfam:AAA_7	2362	2610	3.3e-11	PFAM
low complexity region	2697	2714	N/A	INTRINSIC
low complexity region	2722	2733	N/A	INTRINSIC
low complexity region	2800	2810	N/A	INTRINSIC
low complexity region	3116	3134	N/A	INTRINSIC
Pfam:MT	3178	3470	3.9e-16	PFAM
coiled coil region	3590	3642	N/A	INTRINSIC
coiled coil region	3816	3843	N/A	INTRINSIC
Pfam:Dynein_heavy	3976	4746	7.3e-97	PFAM

Meta Mutation Damage Score

0.1515

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 98.9%

Validation Efficiency

100% (75/75)

Allele List at MGI

All alleles(1) : Gene trapped(1)

Other mutations in this stock

Total: 75 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca8a	A	T	11: 109,974,326 (GRCm39)	S203T	probably damaging	Het
Adat1	A	T	8: 112,716,494 (GRCm39)	M76K	probably damaging	Het
Ankrd33	G	C	15: 101,014,780 (GRCm39)	V56L	probably benign	Het
Ascc3	T	A	10: 50,592,725 (GRCm39)	L1134I	possibly damaging	Het
C3	T	G	17: 57,524,286 (GRCm39)	D948A	probably damaging	Het
Ccdc121rt3	A	C	5: 112,503,395 (GRCm39)	M103R	probably benign	Het
Ccdc40	A	G	11: 119,122,612 (GRCm39)	E138G	possibly damaging	Het
Cd80	A	G	16: 38,306,866 (GRCm39)		probably null	Het
Cdca7	T	A	2: 72,309,873 (GRCm39)		probably null	Het
Chit1	A	G	1: 134,079,030 (GRCm39)	S447G	probably benign	Het
Cmya5	C	T	13: 93,205,786 (GRCm39)		probably null	Het
Cnnm2	A	T	19: 46,750,989 (GRCm39)	I260F	probably damaging	Het
Cnnm2	T	A	19: 46,847,379 (GRCm39)		probably null	Het
Col1a2	T	C	6: 4,534,639 (GRCm39)	L881P	unknown	Het
Crebbp	A	T	16: 3,935,187 (GRCm39)	S901T	probably damaging	Het
Dcun1d2	T	C	8: 13,321,637 (GRCm39)	Y158C	probably damaging	Het
Donson	A	G	16: 91,478,218 (GRCm39)	Y428H	probably damaging	Het
Dsp	G	T	13: 38,375,716 (GRCm39)	W1167L	probably benign	Het
Elmo2	C	T	2: 165,136,961 (GRCm39)	V592M	probably damaging	Het
Enpp3	T	A	10: 24,702,093 (GRCm39)	E60D	probably damaging	Het
Erfl	A	T	7: 24,631,089 (GRCm39)		probably null	Het
Fam83b	TAAGA	T	9: 76,409,394 (GRCm39)		probably null	Het
Fbxo38	A	G	18: 62,669,295 (GRCm39)	C52R	probably damaging	Het
Gm10912	T	C	2: 103,897,055 (GRCm39)	W65R	probably damaging	Het
Gm43518	A	T	5: 124,074,490 (GRCm39)	M44L	probably benign	Het
Gnb1	T	A	4: 155,637,913 (GRCm39)	D212E	probably damaging	Het
Gnl1	A	G	17: 36,299,620 (GRCm39)	N597S	probably damaging	Het
Gprin1	T	G	13: 54,886,855 (GRCm39)	E473A	probably benign	Het
Ighv1-69	T	A	12: 115,586,834 (GRCm39)	M100L	probably benign	Het
Igkv14-100	T	C	6: 68,496,193 (GRCm39)	S29P	probably damaging	Het
Ints6	A	G	14: 62,951,786 (GRCm39)	V232A	probably damaging	Het
Jup	A	G	11: 100,270,379 (GRCm39)	L376P	probably damaging	Het
Kdr	A	T	5: 76,132,920 (GRCm39)	Y119*	probably null	Het
Kif1a	T	G	1: 92,993,820 (GRCm39)	T377P	probably benign	Het
Lama5	C	A	2: 179,822,524 (GRCm39)	V2850L	probably damaging	Het
Lrp2	T	C	2: 69,313,552 (GRCm39)	Y2393C	probably damaging	Het
Mfsd13a	C	T	19: 46,356,763 (GRCm39)	Q255*	probably null	Het
Msh3	A	C	13: 92,372,096 (GRCm39)	D891E	probably damaging	Het
Msl2	A	G	9: 100,957,335 (GRCm39)	N2D	possibly damaging	Het
Myo19	T	C	11: 84,791,373 (GRCm39)	L476P	probably damaging	Het
Nbeal2	G	A	9: 110,467,686 (GRCm39)	R501W	probably damaging	Het
Nfasc	C	A	1: 132,548,787 (GRCm39)	K293N	probably damaging	Het
Npbwr1	A	T	1: 5,987,319 (GRCm39)	L65Q	probably damaging	Het
Nrbp1	T	A	5: 31,401,825 (GRCm39)	D34E	probably damaging	Het
Nup205	T	A	6: 35,220,871 (GRCm39)	V1891D	probably benign	Het
Or51g2	T	A	7: 102,623,175 (GRCm39)	N8I	possibly damaging	Het
Or5g29	T	A	2: 85,420,942 (GRCm39)	D19E	probably benign	Het
Or5k1b	T	C	16: 58,581,482 (GRCm39)	N19S	probably benign	Het
Or8g22	G	T	9: 38,958,379 (GRCm39)	C156*	probably null	Het
Oscp1	G	A	4: 125,976,783 (GRCm39)		probably null	Het
Pcdhgb7	A	G	18: 37,886,086 (GRCm39)	T419A	probably damaging	Het
Pdzph1	T	C	17: 59,281,121 (GRCm39)	D387G	probably benign	Het
Phc1	A	G	6: 122,311,990 (GRCm39)	F56S	probably damaging	Het
Pik3c2g	A	G	6: 139,599,061 (GRCm39)	E59G	possibly damaging	Het
Prickle1	G	T	15: 93,398,752 (GRCm39)	T692K	possibly damaging	Het
Rbm45	T	A	2: 76,206,738 (GRCm39)	L250Q	probably damaging	Het
Ror1	T	A	4: 100,265,108 (GRCm39)	M194K	probably damaging	Het
Rrbp1	T	A	2: 143,799,722 (GRCm39)		probably null	Het
Rundc3b	T	C	5: 8,562,348 (GRCm39)	K340R	probably null	Het
Scn1a	T	A	2: 66,148,243 (GRCm39)	T1101S	probably damaging	Het
Sdk1	C	G	5: 142,080,412 (GRCm39)		probably null	Het
Skic2	A	G	17: 35,064,183 (GRCm39)	F501S	possibly damaging	Het
Slc20a1	T	A	2: 129,041,979 (GRCm39)	M114K	probably damaging	Het
Sorl1	A	C	9: 41,881,047 (GRCm39)	I2158S	probably benign	Het
Strip1	A	T	3: 107,534,111 (GRCm39)	F174L	probably benign	Het
Sucnr1	A	T	3: 59,993,699 (GRCm39)	I76L	probably benign	Het
Syt17	C	T	7: 118,007,242 (GRCm39)	V412I	probably benign	Het
Tie1	T	A	4: 118,346,850 (GRCm39)	H18L	probably benign	Het
Tpp1	T	G	7: 105,398,129 (GRCm39)	K345Q	probably damaging	Het
Trcg1	G	A	9: 57,148,852 (GRCm39)	M141I	possibly damaging	Het
Trpc4ap	T	C	2: 155,499,742 (GRCm39)	N260S	probably benign	Het
Vps41	C	A	13: 19,026,438 (GRCm39)	T512K	possibly damaging	Het
Vps52	A	T	17: 34,178,293 (GRCm39)	M147L	probably benign	Het
Ywhaq	A	G	12: 21,441,752 (GRCm39)		probably benign	Het
Zfp619	A	G	7: 39,184,387 (GRCm39)	N139S	probably benign	Het

Other mutations in Dnhd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00321:Dnhd1	APN	7	105,327,202 (GRCm39)	missense	probably damaging	1.00
IGL00516:Dnhd1	APN	7	105,306,418 (GRCm39)	missense	possibly damaging	0.52
IGL00576:Dnhd1	APN	7	105,341,882 (GRCm39)	missense	probably damaging	1.00
IGL00990:Dnhd1	APN	7	105,370,895 (GRCm39)	missense	possibly damaging	0.85
IGL01346:Dnhd1	APN	7	105,363,116 (GRCm39)	missense	probably benign
IGL01714:Dnhd1	APN	7	105,370,149 (GRCm39)	missense	probably damaging	1.00
IGL01735:Dnhd1	APN	7	105,362,961 (GRCm39)	missense	probably benign	0.37
IGL01814:Dnhd1	APN	7	105,301,237 (GRCm39)	missense	probably benign
IGL01999:Dnhd1	APN	7	105,370,422 (GRCm39)	missense	possibly damaging	0.50
IGL02022:Dnhd1	APN	7	105,327,516 (GRCm39)	missense	probably damaging	1.00
IGL02131:Dnhd1	APN	7	105,370,009 (GRCm39)	missense	probably damaging	1.00
IGL02156:Dnhd1	APN	7	105,370,951 (GRCm39)	missense	probably damaging	1.00
IGL02674:Dnhd1	APN	7	105,370,688 (GRCm39)	missense	probably benign	0.00
IGL02966:Dnhd1	APN	7	105,369,948 (GRCm39)	missense	probably benign	0.00
IGL03066:Dnhd1	APN	7	105,369,089 (GRCm39)	missense	probably damaging	0.99
IGL03298:Dnhd1	APN	7	105,363,682 (GRCm39)	missense	probably damaging	0.98
IGL03378:Dnhd1	APN	7	105,362,940 (GRCm39)	missense	possibly damaging	0.87
IGL02802:Dnhd1	UTSW	7	105,304,930 (GRCm39)	missense	possibly damaging	0.83
R0060:Dnhd1	UTSW	7	105,317,721 (GRCm39)	missense	probably damaging	0.99
R0129:Dnhd1	UTSW	7	105,370,131 (GRCm39)	missense	probably benign	0.19
R0238:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0238:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0239:Dnhd1	UTSW	7	105,370,738 (GRCm39)	missense	probably benign	0.06
R0384:Dnhd1	UTSW	7	105,369,321 (GRCm39)	missense	possibly damaging	0.56
R0453:Dnhd1	UTSW	7	105,323,651 (GRCm39)	missense	probably benign	0.00
R0540:Dnhd1	UTSW	7	105,369,995 (GRCm39)	missense	probably benign	0.04
R0554:Dnhd1	UTSW	7	105,343,602 (GRCm39)	missense	probably benign	0.10
R0576:Dnhd1	UTSW	7	105,363,252 (GRCm39)	missense	probably damaging	1.00
R0607:Dnhd1	UTSW	7	105,369,995 (GRCm39)	missense	probably benign	0.04
R0631:Dnhd1	UTSW	7	105,300,831 (GRCm39)	missense	probably benign	0.17
R0639:Dnhd1	UTSW	7	105,345,671 (GRCm39)	missense	possibly damaging	0.95
R0668:Dnhd1	UTSW	7	105,344,958 (GRCm39)	missense	probably benign
R0669:Dnhd1	UTSW	7	105,342,911 (GRCm39)	missense	probably benign	0.01
R0670:Dnhd1	UTSW	7	105,345,671 (GRCm39)	missense	possibly damaging	0.95
R0699:Dnhd1	UTSW	7	105,301,113 (GRCm39)	missense	probably damaging	0.98
R1019:Dnhd1	UTSW	7	105,358,378 (GRCm39)	missense	probably damaging	1.00
R1144:Dnhd1	UTSW	7	105,362,238 (GRCm39)	missense	probably damaging	1.00
R1226:Dnhd1	UTSW	7	105,346,106 (GRCm39)	missense	probably damaging	1.00
R1257:Dnhd1	UTSW	7	105,343,360 (GRCm39)	missense	probably damaging	1.00
R1391:Dnhd1	UTSW	7	105,369,331 (GRCm39)	missense	probably damaging	1.00
R1453:Dnhd1	UTSW	7	105,370,480 (GRCm39)	critical splice donor site	probably null
R1501:Dnhd1	UTSW	7	105,317,670 (GRCm39)	missense	probably benign	0.00
R1503:Dnhd1	UTSW	7	105,342,867 (GRCm39)	missense	possibly damaging	0.67
R1515:Dnhd1	UTSW	7	105,353,355 (GRCm39)	missense	probably benign	0.11
R1615:Dnhd1	UTSW	7	105,362,913 (GRCm39)	missense	possibly damaging	0.74
R1615:Dnhd1	UTSW	7	105,352,413 (GRCm39)	missense	probably benign	0.00
R1656:Dnhd1	UTSW	7	105,363,488 (GRCm39)	missense	probably damaging	1.00
R1720:Dnhd1	UTSW	7	105,343,035 (GRCm39)	missense	probably benign
R1723:Dnhd1	UTSW	7	105,364,127 (GRCm39)	missense	possibly damaging	0.60
R1766:Dnhd1	UTSW	7	105,343,179 (GRCm39)	missense	possibly damaging	0.50
R1799:Dnhd1	UTSW	7	105,304,974 (GRCm39)	missense	probably benign	0.31
R1860:Dnhd1	UTSW	7	105,353,412 (GRCm39)	missense	probably benign
R1920:Dnhd1	UTSW	7	105,362,614 (GRCm39)	missense	probably benign	0.00
R1925:Dnhd1	UTSW	7	105,323,061 (GRCm39)	missense	probably damaging	0.96
R1925:Dnhd1	UTSW	7	105,301,459 (GRCm39)	missense	probably damaging	1.00
R1934:Dnhd1	UTSW	7	105,357,789 (GRCm39)	missense	probably benign	0.05
R1935:Dnhd1	UTSW	7	105,323,183 (GRCm39)	missense	probably benign	0.09
R1936:Dnhd1	UTSW	7	105,323,183 (GRCm39)	missense	probably benign	0.09
R2035:Dnhd1	UTSW	7	105,354,128 (GRCm39)	missense	probably damaging	0.99
R2125:Dnhd1	UTSW	7	105,327,178 (GRCm39)	missense	probably benign	0.35
R2127:Dnhd1	UTSW	7	105,342,928 (GRCm39)	missense	possibly damaging	0.56
R2254:Dnhd1	UTSW	7	105,352,979 (GRCm39)	missense	probably damaging	1.00
R2301:Dnhd1	UTSW	7	105,354,606 (GRCm39)	missense	probably damaging	1.00
R2316:Dnhd1	UTSW	7	105,323,628 (GRCm39)	missense	probably damaging	1.00
R2324:Dnhd1	UTSW	7	105,359,297 (GRCm39)	missense	probably damaging	1.00
R2337:Dnhd1	UTSW	7	105,352,674 (GRCm39)	missense	probably benign	0.07
R2381:Dnhd1	UTSW	7	105,342,871 (GRCm39)	missense	probably benign	0.42
R2394:Dnhd1	UTSW	7	105,369,438 (GRCm39)	missense	probably benign	0.19
R2862:Dnhd1	UTSW	7	105,361,766 (GRCm39)	missense	probably benign	0.01
R3038:Dnhd1	UTSW	7	105,369,436 (GRCm39)	missense	probably damaging	0.99
R3114:Dnhd1	UTSW	7	105,345,772 (GRCm39)	critical splice donor site	probably null
R3404:Dnhd1	UTSW	7	105,343,968 (GRCm39)	nonsense	probably null
R3405:Dnhd1	UTSW	7	105,343,968 (GRCm39)	nonsense	probably null
R3439:Dnhd1	UTSW	7	105,343,992 (GRCm39)	missense	probably damaging	1.00
R3959:Dnhd1	UTSW	7	105,362,329 (GRCm39)	missense	probably benign	0.21
R4014:Dnhd1	UTSW	7	105,364,045 (GRCm39)	missense	probably damaging	0.99
R4084:Dnhd1	UTSW	7	105,358,795 (GRCm39)	missense	probably damaging	1.00
R4181:Dnhd1	UTSW	7	105,343,161 (GRCm39)	missense	probably damaging	1.00
R4255:Dnhd1	UTSW	7	105,362,205 (GRCm39)	missense	probably damaging	1.00
R4302:Dnhd1	UTSW	7	105,343,161 (GRCm39)	missense	probably damaging	1.00
R4440:Dnhd1	UTSW	7	105,345,935 (GRCm39)	nonsense	probably null
R4565:Dnhd1	UTSW	7	105,301,163 (GRCm39)	missense	possibly damaging	0.92
R4569:Dnhd1	UTSW	7	105,306,373 (GRCm39)	splice site	probably null
R4584:Dnhd1	UTSW	7	105,327,256 (GRCm39)	missense	probably damaging	1.00
R4586:Dnhd1	UTSW	7	105,327,256 (GRCm39)	missense	probably damaging	1.00
R4590:Dnhd1	UTSW	7	105,363,237 (GRCm39)	missense	probably damaging	1.00
R4593:Dnhd1	UTSW	7	105,364,653 (GRCm39)	missense	probably benign	0.02
R4600:Dnhd1	UTSW	7	105,352,851 (GRCm39)	missense	probably damaging	1.00
R4705:Dnhd1	UTSW	7	105,304,948 (GRCm39)	missense	probably damaging	1.00
R4731:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4732:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4733:Dnhd1	UTSW	7	105,323,056 (GRCm39)	missense	probably benign	0.00
R4786:Dnhd1	UTSW	7	105,323,651 (GRCm39)	missense	probably benign	0.00
R4791:Dnhd1	UTSW	7	105,370,324 (GRCm39)	missense	probably damaging	1.00
R4811:Dnhd1	UTSW	7	105,363,488 (GRCm39)	missense	probably damaging	0.99
R4822:Dnhd1	UTSW	7	105,353,171 (GRCm39)	missense	probably benign	0.00
R4886:Dnhd1	UTSW	7	105,364,015 (GRCm39)	missense	probably benign	0.00
R4890:Dnhd1	UTSW	7	105,306,164 (GRCm39)	missense	possibly damaging	0.47
R4973:Dnhd1	UTSW	7	105,362,840 (GRCm39)	missense	probably benign	0.24
R5007:Dnhd1	UTSW	7	105,362,283 (GRCm39)	missense	probably damaging	1.00
R5048:Dnhd1	UTSW	7	105,342,904 (GRCm39)	missense	probably benign	0.01
R5151:Dnhd1	UTSW	7	105,362,647 (GRCm39)	missense	probably benign	0.22
R5179:Dnhd1	UTSW	7	105,363,759 (GRCm39)	missense	probably damaging	1.00
R5182:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5183:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5185:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5209:Dnhd1	UTSW	7	105,345,667 (GRCm39)	missense	probably benign	0.00
R5225:Dnhd1	UTSW	7	105,353,130 (GRCm39)	missense	possibly damaging	0.73
R5250:Dnhd1	UTSW	7	105,334,968 (GRCm39)	missense	probably damaging	1.00
R5257:Dnhd1	UTSW	7	105,323,244 (GRCm39)	missense	probably benign
R5258:Dnhd1	UTSW	7	105,323,244 (GRCm39)	missense	probably benign
R5273:Dnhd1	UTSW	7	105,363,689 (GRCm39)	missense	probably damaging	0.99
R5288:Dnhd1	UTSW	7	105,363,644 (GRCm39)	missense	possibly damaging	0.94
R5396:Dnhd1	UTSW	7	105,362,891 (GRCm39)	missense	probably benign	0.00
R5453:Dnhd1	UTSW	7	105,359,330 (GRCm39)	missense	probably damaging	1.00
R5511:Dnhd1	UTSW	7	105,363,363 (GRCm39)	missense	probably damaging	1.00
R5518:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5523:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5528:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5529:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5561:Dnhd1	UTSW	7	105,364,028 (GRCm39)	missense	probably damaging	0.99
R5681:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5682:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5683:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5684:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5686:Dnhd1	UTSW	7	105,352,416 (GRCm39)	missense	probably damaging	1.00
R5697:Dnhd1	UTSW	7	105,323,395 (GRCm39)	missense	probably damaging	1.00
R5789:Dnhd1	UTSW	7	105,354,217 (GRCm39)	missense	possibly damaging	0.50
R5790:Dnhd1	UTSW	7	105,304,981 (GRCm39)	missense	probably damaging	1.00
R5814:Dnhd1	UTSW	7	105,369,102 (GRCm39)	missense	possibly damaging	0.69
R5828:Dnhd1	UTSW	7	105,369,388 (GRCm39)	missense	probably benign	0.00
R5852:Dnhd1	UTSW	7	105,344,955 (GRCm39)	missense	probably damaging	1.00
R5883:Dnhd1	UTSW	7	105,369,711 (GRCm39)	missense	probably damaging	0.98
R6115:Dnhd1	UTSW	7	105,363,194 (GRCm39)	missense	probably benign	0.00
R6119:Dnhd1	UTSW	7	105,358,647 (GRCm39)	missense	probably benign	0.18
R6212:Dnhd1	UTSW	7	105,353,255 (GRCm39)	missense	probably damaging	1.00
R6243:Dnhd1	UTSW	7	105,301,216 (GRCm39)	missense	probably damaging	1.00
R6265:Dnhd1	UTSW	7	105,342,577 (GRCm39)	missense	probably benign	0.07
R6332:Dnhd1	UTSW	7	105,343,273 (GRCm39)	missense	probably benign	0.02
R6344:Dnhd1	UTSW	7	105,343,817 (GRCm39)	missense	probably benign	0.38
R6477:Dnhd1	UTSW	7	105,327,093 (GRCm39)	missense	probably benign	0.05
R6642:Dnhd1	UTSW	7	105,353,006 (GRCm39)	missense	probably benign
R6663:Dnhd1	UTSW	7	105,334,899 (GRCm39)	splice site	probably null
R6730:Dnhd1	UTSW	7	105,353,082 (GRCm39)	missense	probably benign	0.00
R6748:Dnhd1	UTSW	7	105,369,844 (GRCm39)	missense	probably benign	0.03
R6833:Dnhd1	UTSW	7	105,352,580 (GRCm39)	missense	probably benign	0.01
R6850:Dnhd1	UTSW	7	105,369,137 (GRCm39)	missense	possibly damaging	0.68
R6853:Dnhd1	UTSW	7	105,352,935 (GRCm39)	missense	probably benign
R6860:Dnhd1	UTSW	7	105,327,473 (GRCm39)	missense	probably benign
R6898:Dnhd1	UTSW	7	105,336,584 (GRCm39)	missense	probably damaging	0.99
R6927:Dnhd1	UTSW	7	105,364,770 (GRCm39)	missense	probably damaging	1.00
R6952:Dnhd1	UTSW	7	105,362,895 (GRCm39)	missense	probably damaging	1.00
R6987:Dnhd1	UTSW	7	105,353,792 (GRCm39)	missense	probably damaging	0.98
R6988:Dnhd1	UTSW	7	105,363,417 (GRCm39)	missense	probably damaging	1.00
R7053:Dnhd1	UTSW	7	105,344,161 (GRCm39)	missense	probably damaging	1.00
R7085:Dnhd1	UTSW	7	105,364,468 (GRCm39)	missense	probably benign	0.26
R7086:Dnhd1	UTSW	7	105,357,739 (GRCm39)	missense	probably benign	0.03
R7112:Dnhd1	UTSW	7	105,363,192 (GRCm39)	missense	probably damaging	1.00
R7140:Dnhd1	UTSW	7	105,342,973 (GRCm39)	missense	probably benign	0.00
R7151:Dnhd1	UTSW	7	105,359,234 (GRCm39)	missense	probably benign	0.03
R7178:Dnhd1	UTSW	7	105,344,200 (GRCm39)	missense	probably damaging	0.98
R7326:Dnhd1	UTSW	7	105,370,137 (GRCm39)	missense	probably damaging	0.96
R7345:Dnhd1	UTSW	7	105,353,174 (GRCm39)	missense	probably benign	0.17
R7349:Dnhd1	UTSW	7	105,359,330 (GRCm39)	missense	probably damaging	1.00
R7397:Dnhd1	UTSW	7	105,354,504 (GRCm39)	missense	possibly damaging	0.87
R7520:Dnhd1	UTSW	7	105,345,255 (GRCm39)	missense	probably benign	0.07
R7536:Dnhd1	UTSW	7	105,358,768 (GRCm39)	missense	probably damaging	1.00
R7539:Dnhd1	UTSW	7	105,370,119 (GRCm39)	missense	probably damaging	1.00
R7541:Dnhd1	UTSW	7	105,327,516 (GRCm39)	missense	probably damaging	1.00
R7619:Dnhd1	UTSW	7	105,323,475 (GRCm39)	missense	probably benign	0.01
R7676:Dnhd1	UTSW	7	105,333,294 (GRCm39)	missense	probably benign	0.09
R7689:Dnhd1	UTSW	7	105,363,170 (GRCm39)	missense	probably benign	0.07
R7712:Dnhd1	UTSW	7	105,300,831 (GRCm39)	missense	probably benign	0.17
R7729:Dnhd1	UTSW	7	105,354,472 (GRCm39)	missense	probably damaging	1.00
R7767:Dnhd1	UTSW	7	105,343,817 (GRCm39)	missense	probably benign	0.38
R7768:Dnhd1	UTSW	7	105,370,302 (GRCm39)	missense	possibly damaging	0.87
R7779:Dnhd1	UTSW	7	105,327,122 (GRCm39)	missense	probably benign	0.01
R7879:Dnhd1	UTSW	7	105,352,646 (GRCm39)	missense	probably benign	0.09
R7922:Dnhd1	UTSW	7	105,317,721 (GRCm39)	missense	probably damaging	1.00
R7951:Dnhd1	UTSW	7	105,327,211 (GRCm39)	missense	probably damaging	1.00
R8259:Dnhd1	UTSW	7	105,343,995 (GRCm39)	missense	probably benign	0.38
R8350:Dnhd1	UTSW	7	105,327,231 (GRCm39)	missense	probably damaging	0.99
R8380:Dnhd1	UTSW	7	105,327,073 (GRCm39)	missense	probably benign	0.31
R8392:Dnhd1	UTSW	7	105,352,550 (GRCm39)	missense	possibly damaging	0.84
R8478:Dnhd1	UTSW	7	105,332,001 (GRCm39)	missense	probably benign	0.00
R8708:Dnhd1	UTSW	7	105,343,487 (GRCm39)	nonsense	probably null
R8767:Dnhd1	UTSW	7	105,301,330 (GRCm39)	missense	probably damaging	1.00
R8825:Dnhd1	UTSW	7	105,343,174 (GRCm39)	missense	possibly damaging	0.95
R8849:Dnhd1	UTSW	7	105,370,723 (GRCm39)	missense	probably benign	0.00
R8903:Dnhd1	UTSW	7	105,362,855 (GRCm39)	nonsense	probably null
R8910:Dnhd1	UTSW	7	105,332,904 (GRCm39)	missense	possibly damaging	0.92
R8940:Dnhd1	UTSW	7	105,363,854 (GRCm39)	intron	probably benign
R8954:Dnhd1	UTSW	7	105,343,986 (GRCm39)	missense	probably benign	0.35
R8956:Dnhd1	UTSW	7	105,341,852 (GRCm39)	missense	probably damaging	0.99
R8971:Dnhd1	UTSW	7	105,358,528 (GRCm39)	nonsense	probably null
R8996:Dnhd1	UTSW	7	105,323,242 (GRCm39)	missense	probably damaging	1.00
R9051:Dnhd1	UTSW	7	105,341,933 (GRCm39)	missense	possibly damaging	0.54
R9058:Dnhd1	UTSW	7	105,333,270 (GRCm39)	missense	probably benign	0.01
R9109:Dnhd1	UTSW	7	105,333,173 (GRCm39)	missense	probably damaging	0.98
R9284:Dnhd1	UTSW	7	105,301,091 (GRCm39)	missense	probably damaging	1.00
R9295:Dnhd1	UTSW	7	105,363,348 (GRCm39)	missense	probably benign
R9298:Dnhd1	UTSW	7	105,333,173 (GRCm39)	missense	probably damaging	0.98
R9299:Dnhd1	UTSW	7	105,369,806 (GRCm39)	missense	probably benign	0.00
R9308:Dnhd1	UTSW	7	105,353,484 (GRCm39)	missense	probably damaging	1.00
R9337:Dnhd1	UTSW	7	105,369,806 (GRCm39)	missense	probably benign	0.00
R9385:Dnhd1	UTSW	7	105,361,972 (GRCm39)	missense	probably damaging	1.00
R9463:Dnhd1	UTSW	7	105,344,223 (GRCm39)	missense	probably benign
R9463:Dnhd1	UTSW	7	105,306,454 (GRCm39)	missense	probably benign	0.00
R9476:Dnhd1	UTSW	7	105,352,889 (GRCm39)	missense	possibly damaging	0.74
R9489:Dnhd1	UTSW	7	105,300,804 (GRCm39)	missense	probably benign
R9500:Dnhd1	UTSW	7	105,353,709 (GRCm39)	missense	probably benign
R9510:Dnhd1	UTSW	7	105,352,889 (GRCm39)	missense	possibly damaging	0.74
R9513:Dnhd1	UTSW	7	105,354,179 (GRCm39)	missense	probably damaging	1.00
R9537:Dnhd1	UTSW	7	105,344,740 (GRCm39)	missense	probably damaging	0.99
R9567:Dnhd1	UTSW	7	105,353,473 (GRCm39)	missense	probably benign	0.03
R9622:Dnhd1	UTSW	7	105,353,342 (GRCm39)	missense	probably benign
R9623:Dnhd1	UTSW	7	105,344,134 (GRCm39)	missense	probably damaging	1.00
R9623:Dnhd1	UTSW	7	105,335,773 (GRCm39)	missense	probably damaging	1.00
R9674:Dnhd1	UTSW	7	105,363,429 (GRCm39)	missense	probably damaging	1.00
R9756:Dnhd1	UTSW	7	105,353,135 (GRCm39)	missense	probably benign	0.19
R9777:Dnhd1	UTSW	7	105,369,456 (GRCm39)	missense	probably benign	0.14
R9778:Dnhd1	UTSW	7	105,353,240 (GRCm39)	missense	probably benign
R9781:Dnhd1	UTSW	7	105,352,917 (GRCm39)	missense	probably benign	0.31
R9796:Dnhd1	UTSW	7	105,342,537 (GRCm39)	missense	probably damaging	1.00
Z1088:Dnhd1	UTSW	7	105,361,934 (GRCm39)	missense	probably benign	0.00
Z1176:Dnhd1	UTSW	7	105,352,243 (GRCm39)	critical splice acceptor site	probably null
Z1176:Dnhd1	UTSW	7	105,327,506 (GRCm39)	missense	probably benign
Z1176:Dnhd1	UTSW	7	105,317,754 (GRCm39)	missense	probably damaging	0.98
Z1176:Dnhd1	UTSW	7	105,352,787 (GRCm39)	frame shift	probably null
Z1177:Dnhd1	UTSW	7	105,332,048 (GRCm39)	missense	possibly damaging	0.90

Predicted Primers

PCR Primer
(F):5'- GTCGTGTTCTCCTGAATGCG -3'
(R):5'- GCATGAGATCTCCAAGGCTG -3'

Sequencing Primer
(F):5'- TGCAGAAGTGTTCATCCACG -3'
(R):5'- TCTCCAAGGCTGAGGTAGG -3'

Posted On

2019-05-13