Incidental Mutation 'R7058:Hfm1'
| ID |
548047 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hfm1
|
| Ensembl Gene |
ENSMUSG00000043410 |
| Gene Name |
HFM1, ATP-dependent DNA helicase homolog |
| Synonyms |
LOC381663, A330009G12Rik, Mer3, Sec63d1 |
| MMRRC Submission |
045155-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.089)
|
| Stock # |
R7058 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
106988058-107074187 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 107059306 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 239
(S239T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142727
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000112690]
[ENSMUST00000117588]
[ENSMUST00000148686]
[ENSMUST00000200249]
|
| AlphaFold |
D3Z4R1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112690
AA Change: S239T
PolyPhen 2
Score 0.037 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000108310
Gene: ENSMUSG00000043410
AA Change: S239T
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117588
AA Change: S239T
PolyPhen 2
Score 0.037 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000112590
Gene: ENSMUSG00000043410
AA Change: S239T
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148686
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200249
AA Change: S239T
PolyPhen 2
Score 0.037 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000142727
Gene: ENSMUSG00000043410
AA Change: S239T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ResIII
|
260 |
410 |
9.9e-7 |
PFAM |
|
Pfam:DEAD
|
281 |
410 |
1.5e-19 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
100% (87/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to be an ATP-dependent DNA helicase and is expressed mainly in germ-line cells. Defects in this gene are a cause of premature ovarian failure 9 (POF9). [provided by RefSeq, Apr 2014]
PHENOTYPE: Meiosis ais disrupted in homozygotes and bothe sexes are sterile [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610021A01Rik |
T |
C |
7: 41,275,554 (GRCm39) |
I419T |
possibly damaging |
Het |
| Afap1 |
T |
C |
5: 36,119,604 (GRCm39) |
V294A |
probably benign |
Het |
| Amotl1 |
T |
A |
9: 14,486,532 (GRCm39) |
Q454L |
possibly damaging |
Het |
| Ap2a1 |
T |
C |
7: 44,550,215 (GRCm39) |
S961G |
probably damaging |
Het |
| Asxl3 |
A |
G |
18: 22,650,731 (GRCm39) |
K907E |
probably damaging |
Het |
| BC028528 |
A |
T |
3: 95,792,323 (GRCm39) |
L137I |
possibly damaging |
Het |
| Cand1 |
A |
T |
10: 119,047,659 (GRCm39) |
N610K |
probably benign |
Het |
| Cat |
A |
G |
2: 103,304,698 (GRCm39) |
I109T |
probably benign |
Het |
| Ccdc18 |
T |
C |
5: 108,341,664 (GRCm39) |
V853A |
probably benign |
Het |
| Chd4 |
C |
A |
6: 125,085,405 (GRCm39) |
D805E |
possibly damaging |
Het |
| Cnih1 |
A |
C |
14: 47,017,652 (GRCm39) |
F77V |
probably damaging |
Het |
| Cntd1 |
A |
T |
11: 101,178,252 (GRCm39) |
I284F |
probably damaging |
Het |
| Col6a3 |
C |
A |
1: 90,755,759 (GRCm39) |
E177* |
probably null |
Het |
| Cpxm2 |
T |
A |
7: 131,745,408 (GRCm39) |
D139V |
probably benign |
Het |
| Cyp1a2 |
G |
T |
9: 57,584,525 (GRCm39) |
R510S |
probably damaging |
Het |
| D2hgdh |
T |
C |
1: 93,763,096 (GRCm39) |
S294P |
probably damaging |
Het |
| Dchs1 |
A |
G |
7: 105,406,228 (GRCm39) |
C2335R |
probably benign |
Het |
| Disc1 |
G |
T |
8: 125,977,724 (GRCm39) |
C719F |
probably damaging |
Het |
| Dnah14 |
A |
C |
1: 181,525,614 (GRCm39) |
D2180A |
probably benign |
Het |
| Dop1b |
G |
A |
16: 93,573,878 (GRCm39) |
R1582Q |
probably benign |
Het |
| Dsg2 |
A |
T |
18: 20,725,332 (GRCm39) |
H481L |
probably benign |
Het |
| Epha6 |
A |
G |
16: 59,503,013 (GRCm39) |
S965P |
probably damaging |
Het |
| Esrrg |
G |
T |
1: 187,882,503 (GRCm39) |
L253F |
probably damaging |
Het |
| Exoc6b |
T |
C |
6: 84,831,704 (GRCm39) |
K438R |
probably damaging |
Het |
| Fam98a |
C |
A |
17: 75,845,384 (GRCm39) |
R454L |
unknown |
Het |
| Fam98c |
A |
T |
7: 28,855,308 (GRCm39) |
|
probably null |
Het |
| Fhad1 |
CGG |
CG |
4: 141,645,602 (GRCm39) |
|
probably null |
Het |
| Galnt13 |
A |
G |
2: 54,988,587 (GRCm39) |
T470A |
probably damaging |
Het |
| Ggt7 |
A |
T |
2: 155,345,015 (GRCm39) |
|
probably null |
Het |
| Golim4 |
T |
C |
3: 75,785,957 (GRCm39) |
E606G |
probably damaging |
Het |
| Gpd2 |
G |
A |
2: 57,197,112 (GRCm39) |
|
probably null |
Het |
| Grin2b |
T |
C |
6: 135,757,304 (GRCm39) |
M386V |
probably damaging |
Het |
| Hmcn1 |
G |
A |
1: 150,649,641 (GRCm39) |
T615I |
probably benign |
Het |
| Hook2 |
G |
A |
8: 85,724,040 (GRCm39) |
E446K |
possibly damaging |
Het |
| Hsd3b1 |
C |
T |
3: 98,765,131 (GRCm39) |
|
probably null |
Het |
| Igsf9b |
A |
G |
9: 27,234,150 (GRCm39) |
Y421C |
probably damaging |
Het |
| Il21 |
A |
G |
3: 37,286,629 (GRCm39) |
L29P |
probably damaging |
Het |
| Ildr1 |
A |
G |
16: 36,542,730 (GRCm39) |
S421G |
probably benign |
Het |
| Kat2b |
C |
A |
17: 53,972,894 (GRCm39) |
T736K |
probably benign |
Het |
| Kcng1 |
A |
G |
2: 168,104,529 (GRCm39) |
V439A |
probably damaging |
Het |
| Kif21a |
A |
T |
15: 90,833,106 (GRCm39) |
|
probably null |
Het |
| Lat |
A |
G |
7: 125,968,318 (GRCm39) |
|
probably null |
Het |
| Mastl |
T |
A |
2: 23,023,425 (GRCm39) |
K433* |
probably null |
Het |
| Mettl2 |
A |
G |
11: 105,019,719 (GRCm39) |
R119G |
probably benign |
Het |
| Mia2 |
C |
T |
12: 59,231,021 (GRCm39) |
P1223L |
possibly damaging |
Het |
| Mkrn2os |
G |
T |
6: 115,563,635 (GRCm39) |
D133E |
probably benign |
Het |
| Mslnl |
A |
G |
17: 25,962,186 (GRCm39) |
T195A |
probably benign |
Het |
| Muc16 |
T |
G |
9: 18,551,051 (GRCm39) |
T5081P |
probably benign |
Het |
| Mylpf |
G |
C |
7: 126,813,139 (GRCm39) |
R110P |
probably damaging |
Het |
| Myo19 |
G |
T |
11: 84,798,194 (GRCm39) |
C738F |
possibly damaging |
Het |
| Nat8f4 |
T |
A |
6: 85,878,271 (GRCm39) |
N84I |
possibly damaging |
Het |
| Nol8 |
C |
T |
13: 49,829,862 (GRCm39) |
R1104C |
probably damaging |
Het |
| Notch1 |
A |
T |
2: 26,353,830 (GRCm39) |
D1932E |
probably benign |
Het |
| Nsun3 |
A |
T |
16: 62,596,663 (GRCm39) |
C152S |
possibly damaging |
Het |
| Opcml |
G |
A |
9: 28,586,507 (GRCm39) |
W75* |
probably null |
Het |
| Or14j10 |
A |
G |
17: 37,934,597 (GRCm39) |
F310L |
probably benign |
Het |
| Pcdh7 |
G |
A |
5: 57,879,582 (GRCm39) |
E1046K |
probably damaging |
Het |
| Pcdhb9 |
T |
A |
18: 37,536,334 (GRCm39) |
V776D |
probably benign |
Het |
| Pla2g4a |
A |
G |
1: 149,727,103 (GRCm39) |
L551S |
probably damaging |
Het |
| Plaa |
G |
A |
4: 94,458,060 (GRCm39) |
Q637* |
probably null |
Het |
| Plekhh1 |
A |
T |
12: 79,122,204 (GRCm39) |
E1099V |
probably damaging |
Het |
| Ppp4r1 |
A |
T |
17: 66,136,495 (GRCm39) |
N551Y |
probably benign |
Het |
| R3hdm2 |
T |
C |
10: 127,320,382 (GRCm39) |
V554A |
probably damaging |
Het |
| Rab44 |
A |
G |
17: 29,357,150 (GRCm39) |
|
probably null |
Het |
| Rab5c |
G |
A |
11: 100,610,789 (GRCm39) |
R40C |
probably damaging |
Het |
| Rasgrf2 |
T |
C |
13: 92,034,521 (GRCm39) |
T1119A |
probably damaging |
Het |
| Rims2 |
A |
G |
15: 39,449,044 (GRCm39) |
D1194G |
probably damaging |
Het |
| Scarb1 |
A |
T |
5: 125,374,294 (GRCm39) |
C280S |
probably damaging |
Het |
| Sde2 |
T |
C |
1: 180,693,827 (GRCm39) |
F439S |
probably damaging |
Het |
| Setd5 |
T |
C |
6: 113,092,532 (GRCm39) |
I304T |
probably benign |
Het |
| Sipa1l1 |
A |
G |
12: 82,449,896 (GRCm39) |
E1106G |
probably benign |
Het |
| Sis |
T |
G |
3: 72,810,940 (GRCm39) |
S1694R |
probably damaging |
Het |
| Smad9 |
T |
A |
3: 54,693,614 (GRCm39) |
F181Y |
probably benign |
Het |
| Smg1 |
A |
G |
7: 117,797,502 (GRCm39) |
|
probably benign |
Het |
| Sspo |
T |
C |
6: 48,425,516 (GRCm39) |
Y46H |
probably damaging |
Het |
| Tdrd12 |
A |
G |
7: 35,177,534 (GRCm39) |
M940T |
unknown |
Het |
| Tmem44 |
G |
T |
16: 30,366,213 (GRCm39) |
T71K |
possibly damaging |
Het |
| Tmf1 |
T |
A |
6: 97,133,911 (GRCm39) |
E1009V |
probably damaging |
Het |
| Ttc39a |
C |
T |
4: 109,288,763 (GRCm39) |
R288W |
probably damaging |
Het |
| Ttc9c |
G |
A |
19: 8,796,191 (GRCm39) |
|
probably benign |
Het |
| Usp28 |
T |
A |
9: 48,950,456 (GRCm39) |
Y634N |
probably damaging |
Het |
| Vmn1r211 |
C |
T |
13: 23,036,063 (GRCm39) |
M201I |
probably benign |
Het |
| Vmn2r54 |
T |
A |
7: 12,349,722 (GRCm39) |
Q620L |
possibly damaging |
Het |
| Vps13c |
T |
C |
9: 67,831,110 (GRCm39) |
L1580P |
probably benign |
Het |
| Vrk3 |
C |
A |
7: 44,417,890 (GRCm39) |
F308L |
probably damaging |
Het |
| Zdbf2 |
T |
A |
1: 63,346,563 (GRCm39) |
H1647Q |
possibly damaging |
Het |
| Zfp984 |
A |
T |
4: 147,840,002 (GRCm39) |
M283K |
probably benign |
Het |
|
| Other mutations in Hfm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Hfm1
|
APN |
5 |
107,049,996 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL01295:Hfm1
|
APN |
5 |
107,065,472 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01725:Hfm1
|
APN |
5 |
107,065,245 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01758:Hfm1
|
APN |
5 |
107,052,659 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01911:Hfm1
|
APN |
5 |
107,059,410 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02337:Hfm1
|
APN |
5 |
107,052,133 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02472:Hfm1
|
APN |
5 |
107,021,794 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Hfm1
|
APN |
5 |
107,049,627 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02545:Hfm1
|
APN |
5 |
107,043,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02584:Hfm1
|
APN |
5 |
107,026,528 (GRCm39) |
splice site |
probably null |
|
|
IGL02728:Hfm1
|
APN |
5 |
107,026,689 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02881:Hfm1
|
APN |
5 |
107,022,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03108:Hfm1
|
APN |
5 |
107,043,800 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03351:Hfm1
|
APN |
5 |
107,059,441 (GRCm39) |
nonsense |
probably null |
|
|
IGL03353:Hfm1
|
APN |
5 |
107,004,795 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0024:Hfm1
|
UTSW |
5 |
107,004,790 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0024:Hfm1
|
UTSW |
5 |
107,004,790 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0094:Hfm1
|
UTSW |
5 |
107,065,344 (GRCm39) |
missense |
probably benign |
|
|
R0633:Hfm1
|
UTSW |
5 |
107,065,467 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R0644:Hfm1
|
UTSW |
5 |
107,046,122 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1078:Hfm1
|
UTSW |
5 |
107,026,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1120:Hfm1
|
UTSW |
5 |
107,052,084 (GRCm39) |
splice site |
probably benign |
|
|
R1166:Hfm1
|
UTSW |
5 |
107,059,277 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1242:Hfm1
|
UTSW |
5 |
107,022,767 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1414:Hfm1
|
UTSW |
5 |
107,020,219 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1450:Hfm1
|
UTSW |
5 |
107,066,324 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1529:Hfm1
|
UTSW |
5 |
107,000,989 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1622:Hfm1
|
UTSW |
5 |
107,041,389 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1710:Hfm1
|
UTSW |
5 |
107,043,869 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1710:Hfm1
|
UTSW |
5 |
107,028,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1757:Hfm1
|
UTSW |
5 |
107,028,226 (GRCm39) |
splice site |
probably null |
|
|
R1856:Hfm1
|
UTSW |
5 |
106,995,542 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1984:Hfm1
|
UTSW |
5 |
107,046,442 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1985:Hfm1
|
UTSW |
5 |
107,046,442 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2040:Hfm1
|
UTSW |
5 |
107,049,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Hfm1
|
UTSW |
5 |
107,044,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2426:Hfm1
|
UTSW |
5 |
106,995,519 (GRCm39) |
splice site |
probably null |
|
|
R2474:Hfm1
|
UTSW |
5 |
107,020,282 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R2926:Hfm1
|
UTSW |
5 |
107,022,148 (GRCm39) |
nonsense |
probably null |
|
|
R2944:Hfm1
|
UTSW |
5 |
107,020,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3705:Hfm1
|
UTSW |
5 |
107,040,705 (GRCm39) |
unclassified |
probably benign |
|
|
R4256:Hfm1
|
UTSW |
5 |
107,052,663 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4455:Hfm1
|
UTSW |
5 |
107,034,374 (GRCm39) |
splice site |
probably null |
|
|
R4538:Hfm1
|
UTSW |
5 |
107,022,756 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R4540:Hfm1
|
UTSW |
5 |
107,022,087 (GRCm39) |
nonsense |
probably null |
|
|
R4591:Hfm1
|
UTSW |
5 |
106,995,533 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4745:Hfm1
|
UTSW |
5 |
107,049,709 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4747:Hfm1
|
UTSW |
5 |
107,065,389 (GRCm39) |
missense |
probably benign |
|
|
R4765:Hfm1
|
UTSW |
5 |
106,990,405 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4821:Hfm1
|
UTSW |
5 |
107,002,606 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4842:Hfm1
|
UTSW |
5 |
107,040,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4944:Hfm1
|
UTSW |
5 |
107,022,079 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5093:Hfm1
|
UTSW |
5 |
107,049,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5399:Hfm1
|
UTSW |
5 |
107,065,428 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5414:Hfm1
|
UTSW |
5 |
107,049,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5436:Hfm1
|
UTSW |
5 |
107,040,638 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R5459:Hfm1
|
UTSW |
5 |
107,052,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5485:Hfm1
|
UTSW |
5 |
106,995,528 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5585:Hfm1
|
UTSW |
5 |
107,059,305 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5631:Hfm1
|
UTSW |
5 |
107,052,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5705:Hfm1
|
UTSW |
5 |
107,059,319 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5804:Hfm1
|
UTSW |
5 |
107,026,455 (GRCm39) |
splice site |
probably null |
|
|
R5959:Hfm1
|
UTSW |
5 |
107,022,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6046:Hfm1
|
UTSW |
5 |
107,046,509 (GRCm39) |
splice site |
probably null |
|
|
R6191:Hfm1
|
UTSW |
5 |
107,034,419 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6345:Hfm1
|
UTSW |
5 |
106,989,504 (GRCm39) |
missense |
probably benign |
|
|
R6580:Hfm1
|
UTSW |
5 |
106,995,575 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6651:Hfm1
|
UTSW |
5 |
106,995,553 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6761:Hfm1
|
UTSW |
5 |
107,043,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6835:Hfm1
|
UTSW |
5 |
107,026,681 (GRCm39) |
nonsense |
probably null |
|
|
R6891:Hfm1
|
UTSW |
5 |
107,065,240 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R6924:Hfm1
|
UTSW |
5 |
106,998,276 (GRCm39) |
splice site |
probably null |
|
|
R6980:Hfm1
|
UTSW |
5 |
107,028,343 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7054:Hfm1
|
UTSW |
5 |
107,043,909 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7189:Hfm1
|
UTSW |
5 |
107,049,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7250:Hfm1
|
UTSW |
5 |
107,052,197 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7376:Hfm1
|
UTSW |
5 |
107,043,084 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7577:Hfm1
|
UTSW |
5 |
107,043,909 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7636:Hfm1
|
UTSW |
5 |
107,065,332 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7639:Hfm1
|
UTSW |
5 |
107,046,341 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7639:Hfm1
|
UTSW |
5 |
107,037,791 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7763:Hfm1
|
UTSW |
5 |
107,029,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7828:Hfm1
|
UTSW |
5 |
107,029,657 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7905:Hfm1
|
UTSW |
5 |
107,046,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8160:Hfm1
|
UTSW |
5 |
107,043,899 (GRCm39) |
missense |
probably null |
0.00 |
|
R8477:Hfm1
|
UTSW |
5 |
107,029,684 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8739:Hfm1
|
UTSW |
5 |
107,046,371 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8968:Hfm1
|
UTSW |
5 |
107,065,439 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9072:Hfm1
|
UTSW |
5 |
107,046,146 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9073:Hfm1
|
UTSW |
5 |
107,046,146 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9152:Hfm1
|
UTSW |
5 |
106,989,611 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9234:Hfm1
|
UTSW |
5 |
107,041,334 (GRCm39) |
missense |
probably benign |
|
|
R9244:Hfm1
|
UTSW |
5 |
107,022,766 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9576:Hfm1
|
UTSW |
5 |
107,021,938 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9649:Hfm1
|
UTSW |
5 |
107,066,329 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9743:Hfm1
|
UTSW |
5 |
107,022,125 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9782:Hfm1
|
UTSW |
5 |
107,021,896 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9789:Hfm1
|
UTSW |
5 |
107,065,346 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Hfm1
|
UTSW |
5 |
107,019,686 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CAAAGAACCTAAGCCATTTGGG -3'
(R):5'- ACTTGAGTTCTCATATCAGCCC -3'
Sequencing Primer
(F):5'- CACTTTCCATAAAAAGCTCCAATAAC -3'
(R):5'- GAGTTCTCATATCAGCCCAGTGAAAC -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation