Incidental Mutation 'R7058:Rasgrf2'
| ID |
548089 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rasgrf2
|
| Ensembl Gene |
ENSMUSG00000021708 |
| Gene Name |
RAS protein-specific guanine nucleotide-releasing factor 2 |
| Synonyms |
Grf2, 6330417G04Rik |
| MMRRC Submission |
045155-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.191)
|
| Stock # |
R7058 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
92028519-92268164 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 92034521 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1119
(T1119A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000096930
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099326]
|
| AlphaFold |
P70392 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000099326
AA Change: T1119A
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000096930
Gene: ENSMUSG00000021708
AA Change: T1119A
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
23 |
135 |
1.29e-16 |
SMART |
|
IQ
|
204 |
226 |
1.3e0 |
SMART |
|
RhoGEF
|
247 |
428 |
2.2e-51 |
SMART |
|
RasGEFN
|
633 |
775 |
9.35e-15 |
SMART |
|
RasGEFN
|
786 |
923 |
6.04e-9 |
SMART |
|
RasGEF
|
949 |
1186 |
2.97e-112 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000116892
Gene: ENSMUSG00000021708
AA Change: T518A
| Domain | Start | End | E-Value | Type |
|---|
|
RasGEFN
|
33 |
175 |
9.35e-15 |
SMART |
|
RasGEFN
|
186 |
323 |
6.04e-9 |
SMART |
|
RasGEF
|
349 |
586 |
2.97e-112 |
SMART |
|
| Meta Mutation Damage Score |
0.2453 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
100% (87/87) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit decreased Il2 and TNF-alpha production in stimulated T cells. Mice homozygous for mutations in both Rasgrf1 and Rasgrf2 exhibit no additional abnormalities than those observed in the Rasgrf1 mutant mice. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610021A01Rik |
T |
C |
7: 41,275,554 (GRCm39) |
I419T |
possibly damaging |
Het |
| Afap1 |
T |
C |
5: 36,119,604 (GRCm39) |
V294A |
probably benign |
Het |
| Amotl1 |
T |
A |
9: 14,486,532 (GRCm39) |
Q454L |
possibly damaging |
Het |
| Ap2a1 |
T |
C |
7: 44,550,215 (GRCm39) |
S961G |
probably damaging |
Het |
| Asxl3 |
A |
G |
18: 22,650,731 (GRCm39) |
K907E |
probably damaging |
Het |
| BC028528 |
A |
T |
3: 95,792,323 (GRCm39) |
L137I |
possibly damaging |
Het |
| Cand1 |
A |
T |
10: 119,047,659 (GRCm39) |
N610K |
probably benign |
Het |
| Cat |
A |
G |
2: 103,304,698 (GRCm39) |
I109T |
probably benign |
Het |
| Ccdc18 |
T |
C |
5: 108,341,664 (GRCm39) |
V853A |
probably benign |
Het |
| Chd4 |
C |
A |
6: 125,085,405 (GRCm39) |
D805E |
possibly damaging |
Het |
| Cnih1 |
A |
C |
14: 47,017,652 (GRCm39) |
F77V |
probably damaging |
Het |
| Cntd1 |
A |
T |
11: 101,178,252 (GRCm39) |
I284F |
probably damaging |
Het |
| Col6a3 |
C |
A |
1: 90,755,759 (GRCm39) |
E177* |
probably null |
Het |
| Cpxm2 |
T |
A |
7: 131,745,408 (GRCm39) |
D139V |
probably benign |
Het |
| Cyp1a2 |
G |
T |
9: 57,584,525 (GRCm39) |
R510S |
probably damaging |
Het |
| D2hgdh |
T |
C |
1: 93,763,096 (GRCm39) |
S294P |
probably damaging |
Het |
| Dchs1 |
A |
G |
7: 105,406,228 (GRCm39) |
C2335R |
probably benign |
Het |
| Disc1 |
G |
T |
8: 125,977,724 (GRCm39) |
C719F |
probably damaging |
Het |
| Dnah14 |
A |
C |
1: 181,525,614 (GRCm39) |
D2180A |
probably benign |
Het |
| Dop1b |
G |
A |
16: 93,573,878 (GRCm39) |
R1582Q |
probably benign |
Het |
| Dsg2 |
A |
T |
18: 20,725,332 (GRCm39) |
H481L |
probably benign |
Het |
| Epha6 |
A |
G |
16: 59,503,013 (GRCm39) |
S965P |
probably damaging |
Het |
| Esrrg |
G |
T |
1: 187,882,503 (GRCm39) |
L253F |
probably damaging |
Het |
| Exoc6b |
T |
C |
6: 84,831,704 (GRCm39) |
K438R |
probably damaging |
Het |
| Fam98a |
C |
A |
17: 75,845,384 (GRCm39) |
R454L |
unknown |
Het |
| Fam98c |
A |
T |
7: 28,855,308 (GRCm39) |
|
probably null |
Het |
| Fhad1 |
CGG |
CG |
4: 141,645,602 (GRCm39) |
|
probably null |
Het |
| Galnt13 |
A |
G |
2: 54,988,587 (GRCm39) |
T470A |
probably damaging |
Het |
| Ggt7 |
A |
T |
2: 155,345,015 (GRCm39) |
|
probably null |
Het |
| Golim4 |
T |
C |
3: 75,785,957 (GRCm39) |
E606G |
probably damaging |
Het |
| Gpd2 |
G |
A |
2: 57,197,112 (GRCm39) |
|
probably null |
Het |
| Grin2b |
T |
C |
6: 135,757,304 (GRCm39) |
M386V |
probably damaging |
Het |
| Hfm1 |
A |
T |
5: 107,059,306 (GRCm39) |
S239T |
probably benign |
Het |
| Hmcn1 |
G |
A |
1: 150,649,641 (GRCm39) |
T615I |
probably benign |
Het |
| Hook2 |
G |
A |
8: 85,724,040 (GRCm39) |
E446K |
possibly damaging |
Het |
| Hsd3b1 |
C |
T |
3: 98,765,131 (GRCm39) |
|
probably null |
Het |
| Igsf9b |
A |
G |
9: 27,234,150 (GRCm39) |
Y421C |
probably damaging |
Het |
| Il21 |
A |
G |
3: 37,286,629 (GRCm39) |
L29P |
probably damaging |
Het |
| Ildr1 |
A |
G |
16: 36,542,730 (GRCm39) |
S421G |
probably benign |
Het |
| Kat2b |
C |
A |
17: 53,972,894 (GRCm39) |
T736K |
probably benign |
Het |
| Kcng1 |
A |
G |
2: 168,104,529 (GRCm39) |
V439A |
probably damaging |
Het |
| Kif21a |
A |
T |
15: 90,833,106 (GRCm39) |
|
probably null |
Het |
| Lat |
A |
G |
7: 125,968,318 (GRCm39) |
|
probably null |
Het |
| Mastl |
T |
A |
2: 23,023,425 (GRCm39) |
K433* |
probably null |
Het |
| Mettl2 |
A |
G |
11: 105,019,719 (GRCm39) |
R119G |
probably benign |
Het |
| Mia2 |
C |
T |
12: 59,231,021 (GRCm39) |
P1223L |
possibly damaging |
Het |
| Mkrn2os |
G |
T |
6: 115,563,635 (GRCm39) |
D133E |
probably benign |
Het |
| Mslnl |
A |
G |
17: 25,962,186 (GRCm39) |
T195A |
probably benign |
Het |
| Muc16 |
T |
G |
9: 18,551,051 (GRCm39) |
T5081P |
probably benign |
Het |
| Mylpf |
G |
C |
7: 126,813,139 (GRCm39) |
R110P |
probably damaging |
Het |
| Myo19 |
G |
T |
11: 84,798,194 (GRCm39) |
C738F |
possibly damaging |
Het |
| Nat8f4 |
T |
A |
6: 85,878,271 (GRCm39) |
N84I |
possibly damaging |
Het |
| Nol8 |
C |
T |
13: 49,829,862 (GRCm39) |
R1104C |
probably damaging |
Het |
| Notch1 |
A |
T |
2: 26,353,830 (GRCm39) |
D1932E |
probably benign |
Het |
| Nsun3 |
A |
T |
16: 62,596,663 (GRCm39) |
C152S |
possibly damaging |
Het |
| Opcml |
G |
A |
9: 28,586,507 (GRCm39) |
W75* |
probably null |
Het |
| Or14j10 |
A |
G |
17: 37,934,597 (GRCm39) |
F310L |
probably benign |
Het |
| Pcdh7 |
G |
A |
5: 57,879,582 (GRCm39) |
E1046K |
probably damaging |
Het |
| Pcdhb9 |
T |
A |
18: 37,536,334 (GRCm39) |
V776D |
probably benign |
Het |
| Pla2g4a |
A |
G |
1: 149,727,103 (GRCm39) |
L551S |
probably damaging |
Het |
| Plaa |
G |
A |
4: 94,458,060 (GRCm39) |
Q637* |
probably null |
Het |
| Plekhh1 |
A |
T |
12: 79,122,204 (GRCm39) |
E1099V |
probably damaging |
Het |
| Ppp4r1 |
A |
T |
17: 66,136,495 (GRCm39) |
N551Y |
probably benign |
Het |
| R3hdm2 |
T |
C |
10: 127,320,382 (GRCm39) |
V554A |
probably damaging |
Het |
| Rab44 |
A |
G |
17: 29,357,150 (GRCm39) |
|
probably null |
Het |
| Rab5c |
G |
A |
11: 100,610,789 (GRCm39) |
R40C |
probably damaging |
Het |
| Rims2 |
A |
G |
15: 39,449,044 (GRCm39) |
D1194G |
probably damaging |
Het |
| Scarb1 |
A |
T |
5: 125,374,294 (GRCm39) |
C280S |
probably damaging |
Het |
| Sde2 |
T |
C |
1: 180,693,827 (GRCm39) |
F439S |
probably damaging |
Het |
| Setd5 |
T |
C |
6: 113,092,532 (GRCm39) |
I304T |
probably benign |
Het |
| Sipa1l1 |
A |
G |
12: 82,449,896 (GRCm39) |
E1106G |
probably benign |
Het |
| Sis |
T |
G |
3: 72,810,940 (GRCm39) |
S1694R |
probably damaging |
Het |
| Smad9 |
T |
A |
3: 54,693,614 (GRCm39) |
F181Y |
probably benign |
Het |
| Smg1 |
A |
G |
7: 117,797,502 (GRCm39) |
|
probably benign |
Het |
| Sspo |
T |
C |
6: 48,425,516 (GRCm39) |
Y46H |
probably damaging |
Het |
| Tdrd12 |
A |
G |
7: 35,177,534 (GRCm39) |
M940T |
unknown |
Het |
| Tmem44 |
G |
T |
16: 30,366,213 (GRCm39) |
T71K |
possibly damaging |
Het |
| Tmf1 |
T |
A |
6: 97,133,911 (GRCm39) |
E1009V |
probably damaging |
Het |
| Ttc39a |
C |
T |
4: 109,288,763 (GRCm39) |
R288W |
probably damaging |
Het |
| Ttc9c |
G |
A |
19: 8,796,191 (GRCm39) |
|
probably benign |
Het |
| Usp28 |
T |
A |
9: 48,950,456 (GRCm39) |
Y634N |
probably damaging |
Het |
| Vmn1r211 |
C |
T |
13: 23,036,063 (GRCm39) |
M201I |
probably benign |
Het |
| Vmn2r54 |
T |
A |
7: 12,349,722 (GRCm39) |
Q620L |
possibly damaging |
Het |
| Vps13c |
T |
C |
9: 67,831,110 (GRCm39) |
L1580P |
probably benign |
Het |
| Vrk3 |
C |
A |
7: 44,417,890 (GRCm39) |
F308L |
probably damaging |
Het |
| Zdbf2 |
T |
A |
1: 63,346,563 (GRCm39) |
H1647Q |
possibly damaging |
Het |
| Zfp984 |
A |
T |
4: 147,840,002 (GRCm39) |
M283K |
probably benign |
Het |
|
| Other mutations in Rasgrf2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01308:Rasgrf2
|
APN |
13 |
92,159,425 (GRCm39) |
splice site |
probably benign |
|
|
IGL01358:Rasgrf2
|
APN |
13 |
92,130,749 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL01666:Rasgrf2
|
APN |
13 |
92,174,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01930:Rasgrf2
|
APN |
13 |
92,130,857 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02230:Rasgrf2
|
APN |
13 |
92,136,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02630:Rasgrf2
|
APN |
13 |
92,267,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02690:Rasgrf2
|
APN |
13 |
92,167,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Rasgrf2
|
APN |
13 |
92,131,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03067:Rasgrf2
|
APN |
13 |
92,159,413 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03342:Rasgrf2
|
APN |
13 |
92,136,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03405:Rasgrf2
|
APN |
13 |
92,044,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0620:Rasgrf2
|
UTSW |
13 |
92,067,936 (GRCm39) |
splice site |
probably benign |
|
|
R0632:Rasgrf2
|
UTSW |
13 |
92,120,393 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0894:Rasgrf2
|
UTSW |
13 |
92,130,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1354:Rasgrf2
|
UTSW |
13 |
92,165,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1400:Rasgrf2
|
UTSW |
13 |
92,035,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1437:Rasgrf2
|
UTSW |
13 |
92,167,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1443:Rasgrf2
|
UTSW |
13 |
92,131,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1522:Rasgrf2
|
UTSW |
13 |
92,044,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1553:Rasgrf2
|
UTSW |
13 |
92,038,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1613:Rasgrf2
|
UTSW |
13 |
92,050,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1883:Rasgrf2
|
UTSW |
13 |
92,117,149 (GRCm39) |
missense |
probably benign |
|
|
R1934:Rasgrf2
|
UTSW |
13 |
92,131,825 (GRCm39) |
splice site |
probably null |
|
|
R1990:Rasgrf2
|
UTSW |
13 |
92,172,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2037:Rasgrf2
|
UTSW |
13 |
92,050,748 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2043:Rasgrf2
|
UTSW |
13 |
92,167,351 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2135:Rasgrf2
|
UTSW |
13 |
92,120,374 (GRCm39) |
missense |
probably benign |
|
|
R2193:Rasgrf2
|
UTSW |
13 |
92,160,221 (GRCm39) |
splice site |
probably null |
|
|
R2406:Rasgrf2
|
UTSW |
13 |
92,120,359 (GRCm39) |
missense |
probably benign |
|
|
R3055:Rasgrf2
|
UTSW |
13 |
92,165,583 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3916:Rasgrf2
|
UTSW |
13 |
92,167,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3954:Rasgrf2
|
UTSW |
13 |
92,130,974 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3955:Rasgrf2
|
UTSW |
13 |
92,130,974 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3956:Rasgrf2
|
UTSW |
13 |
92,130,974 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4133:Rasgrf2
|
UTSW |
13 |
92,130,773 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R4177:Rasgrf2
|
UTSW |
13 |
92,038,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4178:Rasgrf2
|
UTSW |
13 |
92,038,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4357:Rasgrf2
|
UTSW |
13 |
92,038,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4358:Rasgrf2
|
UTSW |
13 |
92,038,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4359:Rasgrf2
|
UTSW |
13 |
92,038,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Rasgrf2
|
UTSW |
13 |
92,131,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4440:Rasgrf2
|
UTSW |
13 |
92,131,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4441:Rasgrf2
|
UTSW |
13 |
92,131,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4564:Rasgrf2
|
UTSW |
13 |
92,033,773 (GRCm39) |
nonsense |
probably null |
|
|
R4576:Rasgrf2
|
UTSW |
13 |
92,044,529 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R4590:Rasgrf2
|
UTSW |
13 |
92,174,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4718:Rasgrf2
|
UTSW |
13 |
92,138,716 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4778:Rasgrf2
|
UTSW |
13 |
92,131,780 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4790:Rasgrf2
|
UTSW |
13 |
92,136,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4808:Rasgrf2
|
UTSW |
13 |
92,160,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Rasgrf2
|
UTSW |
13 |
92,044,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5286:Rasgrf2
|
UTSW |
13 |
92,267,941 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5902:Rasgrf2
|
UTSW |
13 |
92,068,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6180:Rasgrf2
|
UTSW |
13 |
92,165,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6264:Rasgrf2
|
UTSW |
13 |
92,167,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6369:Rasgrf2
|
UTSW |
13 |
92,267,954 (GRCm39) |
missense |
probably benign |
|
|
R6428:Rasgrf2
|
UTSW |
13 |
92,136,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6595:Rasgrf2
|
UTSW |
13 |
92,167,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6619:Rasgrf2
|
UTSW |
13 |
92,165,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6988:Rasgrf2
|
UTSW |
13 |
92,033,754 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7026:Rasgrf2
|
UTSW |
13 |
92,131,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Rasgrf2
|
UTSW |
13 |
92,130,952 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7045:Rasgrf2
|
UTSW |
13 |
92,159,100 (GRCm39) |
intron |
probably benign |
|
|
R7056:Rasgrf2
|
UTSW |
13 |
92,167,203 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7256:Rasgrf2
|
UTSW |
13 |
92,032,637 (GRCm39) |
nonsense |
probably null |
|
|
R7392:Rasgrf2
|
UTSW |
13 |
92,041,856 (GRCm39) |
missense |
|
|
|
R7469:Rasgrf2
|
UTSW |
13 |
92,165,530 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7618:Rasgrf2
|
UTSW |
13 |
92,136,085 (GRCm39) |
missense |
|
|
|
R7641:Rasgrf2
|
UTSW |
13 |
92,267,914 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7674:Rasgrf2
|
UTSW |
13 |
92,267,914 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7784:Rasgrf2
|
UTSW |
13 |
92,044,201 (GRCm39) |
missense |
|
|
|
R7962:Rasgrf2
|
UTSW |
13 |
92,167,300 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8056:Rasgrf2
|
UTSW |
13 |
92,167,321 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8218:Rasgrf2
|
UTSW |
13 |
92,130,796 (GRCm39) |
missense |
|
|
|
R8796:Rasgrf2
|
UTSW |
13 |
92,038,685 (GRCm39) |
missense |
|
|
|
R8913:Rasgrf2
|
UTSW |
13 |
92,159,034 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8971:Rasgrf2
|
UTSW |
13 |
92,158,225 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9020:Rasgrf2
|
UTSW |
13 |
92,165,146 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9487:Rasgrf2
|
UTSW |
13 |
92,267,759 (GRCm39) |
missense |
probably benign |
|
|
R9562:Rasgrf2
|
UTSW |
13 |
92,034,469 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9712:Rasgrf2
|
UTSW |
13 |
92,136,092 (GRCm39) |
missense |
|
|
|
R9766:Rasgrf2
|
UTSW |
13 |
92,160,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9800:Rasgrf2
|
UTSW |
13 |
92,267,860 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0013:Rasgrf2
|
UTSW |
13 |
92,167,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Rasgrf2
|
UTSW |
13 |
92,050,654 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Rasgrf2
|
UTSW |
13 |
92,159,081 (GRCm39) |
missense |
unknown |
|
|
Z1177:Rasgrf2
|
UTSW |
13 |
92,131,632 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTGGACCTTTATTCCCAACAGG -3'
(R):5'- TGCCCAAACAAGTGTCTCCC -3'
Sequencing Primer
(F):5'- TGGCTAACAAAAGTCGTCTCC -3'
(R):5'- CATCACTTCAGTGTGTAGCTATG -3'
|
| Posted On |
2019-05-13 |
Incidental Mutation