Incidental Mutation 'R7092:Adcy8'
| ID |
550318 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adcy8
|
| Ensembl Gene |
ENSMUSG00000022376 |
| Gene Name |
adenylate cyclase 8 |
| Synonyms |
AC8 |
| MMRRC Submission |
045186-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.082)
|
| Stock # |
R7092 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
64570884-64794145 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 64743619 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Aspartic acid
at position 330
(N330D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000023007
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000023007]
[ENSMUST00000180105]
[ENSMUST00000228014]
|
| AlphaFold |
P97490 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000023007
AA Change: N330D
PolyPhen 2
Score 0.930 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000023007
Gene: ENSMUSG00000022376
AA Change: N330D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
52 |
61 |
N/A |
INTRINSIC |
|
low complexity region
|
111 |
123 |
N/A |
INTRINSIC |
|
low complexity region
|
185 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
255 |
271 |
N/A |
INTRINSIC |
|
CYCc
|
363 |
565 |
3.16e-63 |
SMART |
|
Pfam:DUF1053
|
615 |
710 |
1.3e-30 |
PFAM |
|
transmembrane domain
|
741 |
759 |
N/A |
INTRINSIC |
|
transmembrane domain
|
780 |
802 |
N/A |
INTRINSIC |
|
transmembrane domain
|
833 |
852 |
N/A |
INTRINSIC |
|
transmembrane domain
|
857 |
879 |
N/A |
INTRINSIC |
|
low complexity region
|
900 |
911 |
N/A |
INTRINSIC |
|
CYCc
|
940 |
1155 |
2.19e-48 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000180105
|
| SMART Domains |
Protein: ENSMUSP00000136962
Gene: ENSMUSG00000094296
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
60 |
87 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000228014
AA Change: N330D
PolyPhen 2
Score 0.936 (Sensitivity: 0.80; Specificity: 0.94)
|
| Meta Mutation Damage Score |
0.8427 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
99% (88/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous mutation of this gene results in reduced body size (in female animals only), reduced anxiety, and impaired long term depression (LTD). [provided by MGI curators]
|
| Allele List at MGI |
All alleles(1) : Targeted, knock-out(1) |
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930579F01Rik |
C |
T |
3: 137,889,506 (GRCm39) |
C37Y |
probably benign |
Het |
| A430005L14Rik |
T |
A |
4: 154,045,451 (GRCm39) |
|
probably null |
Het |
| Aadacl2fm3 |
T |
C |
3: 59,768,500 (GRCm39) |
F10S |
probably benign |
Het |
| Abca4 |
C |
G |
3: 121,932,218 (GRCm39) |
P1499A |
probably damaging |
Het |
| Arfgef1 |
A |
G |
1: 10,223,901 (GRCm39) |
Y1466H |
probably damaging |
Het |
| Asz1 |
A |
C |
6: 18,071,818 (GRCm39) |
|
probably null |
Het |
| Atad5 |
T |
A |
11: 80,011,546 (GRCm39) |
N1307K |
possibly damaging |
Het |
| B4galnt4 |
C |
A |
7: 140,648,549 (GRCm39) |
F688L |
probably damaging |
Het |
| Birc6 |
C |
T |
17: 74,953,740 (GRCm39) |
T3349I |
probably damaging |
Het |
| Ccp110 |
C |
A |
7: 118,334,494 (GRCm39) |
A989E |
probably benign |
Het |
| Ccser2 |
A |
G |
14: 36,662,612 (GRCm39) |
S191P |
probably benign |
Het |
| Cdca2 |
A |
G |
14: 67,944,800 (GRCm39) |
|
probably null |
Het |
| Cdcp1 |
T |
A |
9: 123,012,678 (GRCm39) |
T290S |
probably benign |
Het |
| Cep43 |
C |
T |
17: 8,391,802 (GRCm39) |
P161S |
probably benign |
Het |
| Clec2m |
T |
A |
6: 129,299,963 (GRCm39) |
T172S |
probably benign |
Het |
| Cnnm1 |
T |
C |
19: 43,430,387 (GRCm39) |
Y502H |
probably damaging |
Het |
| Cyba |
T |
G |
8: 123,154,437 (GRCm39) |
T29P |
probably damaging |
Het |
| Dcaf12 |
A |
T |
4: 41,301,366 (GRCm39) |
I190N |
probably damaging |
Het |
| Depp1 |
C |
A |
6: 116,628,749 (GRCm39) |
P31T |
probably damaging |
Het |
| Epha1 |
T |
C |
6: 42,341,179 (GRCm39) |
T512A |
probably benign |
Het |
| Fancg |
G |
A |
4: 43,004,831 (GRCm39) |
P454L |
probably benign |
Het |
| Fasn |
A |
C |
11: 120,710,946 (GRCm39) |
V268G |
possibly damaging |
Het |
| Fip1l1 |
T |
A |
5: 74,697,504 (GRCm39) |
L42Q |
probably damaging |
Het |
| Fjx1 |
A |
G |
2: 102,281,101 (GRCm39) |
L278P |
possibly damaging |
Het |
| Fsd1 |
G |
A |
17: 56,300,876 (GRCm39) |
R245H |
probably damaging |
Het |
| Fundc2b |
T |
A |
3: 40,856,809 (GRCm39) |
D22V |
possibly damaging |
Het |
| Gm1527 |
T |
A |
3: 28,968,696 (GRCm39) |
|
probably null |
Het |
| Gng3 |
T |
A |
19: 8,815,611 (GRCm39) |
M42L |
probably benign |
Het |
| Gsdmc2 |
T |
A |
15: 63,696,947 (GRCm39) |
Q408L |
probably damaging |
Het |
| Gtpbp3 |
T |
A |
8: 71,944,909 (GRCm39) |
I388K |
probably benign |
Het |
| Hmcn1 |
A |
T |
1: 150,479,997 (GRCm39) |
W4534R |
probably damaging |
Het |
| Inhca |
G |
A |
9: 103,158,242 (GRCm39) |
S106L |
possibly damaging |
Het |
| Ist1 |
A |
T |
8: 110,409,228 (GRCm39) |
|
probably null |
Het |
| Kifbp |
C |
A |
10: 62,414,079 (GRCm39) |
K26N |
probably damaging |
Het |
| Kyat3 |
T |
C |
3: 142,435,556 (GRCm39) |
I276T |
probably damaging |
Het |
| Lipm |
C |
T |
19: 34,098,758 (GRCm39) |
P411S |
possibly damaging |
Het |
| Lipo3 |
T |
C |
19: 33,591,092 (GRCm39) |
|
probably null |
Het |
| Lrrc9 |
C |
A |
12: 72,510,238 (GRCm39) |
Q446K |
possibly damaging |
Het |
| Mfsd4a |
G |
T |
1: 131,995,401 (GRCm39) |
T77N |
probably benign |
Het |
| Mmp1b |
T |
A |
9: 7,386,981 (GRCm39) |
D77V |
probably damaging |
Het |
| Mrgprb4 |
A |
G |
7: 47,847,984 (GRCm39) |
S315P |
probably benign |
Het |
| Mroh2b |
C |
A |
15: 4,964,160 (GRCm39) |
N887K |
possibly damaging |
Het |
| Mto1 |
A |
G |
9: 78,377,955 (GRCm39) |
K599R |
probably benign |
Het |
| Muc5ac |
T |
C |
7: 141,363,385 (GRCm39) |
|
probably benign |
Het |
| Muc5ac |
G |
C |
7: 141,363,424 (GRCm39) |
|
probably benign |
Het |
| Mylk2 |
A |
G |
2: 152,757,110 (GRCm39) |
N295S |
probably benign |
Het |
| Nr1i3 |
G |
A |
1: 171,041,747 (GRCm39) |
|
probably null |
Het |
| Nup107 |
T |
C |
10: 117,626,399 (GRCm39) |
K25E |
probably damaging |
Het |
| Odc1 |
G |
A |
12: 17,598,314 (GRCm39) |
V152I |
possibly damaging |
Het |
| Or13a20 |
G |
A |
7: 140,232,150 (GRCm39) |
G86D |
probably benign |
Het |
| Or1l4b |
T |
A |
2: 37,036,623 (GRCm39) |
M133K |
probably damaging |
Het |
| Or5m10b |
A |
T |
2: 85,698,951 (GRCm39) |
N5I |
probably damaging |
Het |
| Or7g16 |
G |
A |
9: 18,727,353 (GRCm39) |
P79L |
probably damaging |
Het |
| Pde1b |
G |
T |
15: 103,435,458 (GRCm39) |
V438L |
probably benign |
Het |
| Pde4b |
G |
A |
4: 102,459,048 (GRCm39) |
V523M |
probably damaging |
Het |
| Pdgfc |
C |
T |
3: 81,111,659 (GRCm39) |
P205S |
probably damaging |
Het |
| Per2 |
A |
G |
1: 91,349,153 (GRCm39) |
S1073P |
probably damaging |
Het |
| Plekhg5 |
C |
T |
4: 152,198,965 (GRCm39) |
T1051I |
probably damaging |
Het |
| Ppme1 |
A |
T |
7: 100,021,029 (GRCm39) |
M1K |
probably null |
Het |
| Prokr2 |
A |
T |
2: 132,223,236 (GRCm39) |
V102D |
possibly damaging |
Het |
| Ptk2 |
G |
A |
15: 73,093,658 (GRCm39) |
P854S |
possibly damaging |
Het |
| Ptprh |
C |
A |
7: 4,583,860 (GRCm39) |
|
probably null |
Het |
| Rbsn |
T |
C |
6: 92,166,607 (GRCm39) |
N679S |
probably damaging |
Het |
| Rce1 |
T |
C |
19: 4,673,118 (GRCm39) |
T303A |
probably damaging |
Het |
| Rnf123 |
C |
A |
9: 107,945,799 (GRCm39) |
R329L |
probably benign |
Het |
| Robo2 |
T |
A |
16: 73,753,531 (GRCm39) |
N782I |
probably damaging |
Het |
| Ror2 |
A |
C |
13: 53,264,272 (GRCm39) |
V940G |
probably benign |
Het |
| Rpe65 |
C |
T |
3: 159,321,228 (GRCm39) |
R347C |
probably damaging |
Het |
| Rrp8 |
A |
T |
7: 105,383,316 (GRCm39) |
F317I |
probably damaging |
Het |
| Sidt1 |
A |
G |
16: 44,120,192 (GRCm39) |
V163A |
possibly damaging |
Het |
| Sin3b |
T |
C |
8: 73,474,498 (GRCm39) |
|
probably null |
Het |
| Slamf1 |
A |
G |
1: 171,604,757 (GRCm39) |
T176A |
probably benign |
Het |
| Slc12a4 |
G |
T |
8: 106,671,855 (GRCm39) |
A922D |
probably damaging |
Het |
| Slco1a5 |
T |
A |
6: 142,194,401 (GRCm39) |
Q414L |
probably benign |
Het |
| Snx11 |
C |
A |
11: 96,663,665 (GRCm39) |
R58L |
probably damaging |
Het |
| Sp9 |
A |
G |
2: 73,104,115 (GRCm39) |
D223G |
probably damaging |
Het |
| Sptbn1 |
T |
C |
11: 30,087,119 (GRCm39) |
I1107V |
possibly damaging |
Het |
| Stap2 |
T |
C |
17: 56,309,954 (GRCm39) |
R66G |
probably benign |
Het |
| Synrg |
T |
G |
11: 83,899,683 (GRCm39) |
F552V |
possibly damaging |
Het |
| Trim60 |
C |
T |
8: 65,453,700 (GRCm39) |
R183H |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,733,760 (GRCm39) |
D4505G |
unknown |
Het |
| Ubxn4 |
A |
G |
1: 128,179,959 (GRCm39) |
I34M |
probably benign |
Het |
| Vac14 |
T |
A |
8: 111,442,128 (GRCm39) |
M702K |
probably damaging |
Het |
| Vmn1r43 |
T |
C |
6: 89,846,885 (GRCm39) |
I200M |
probably benign |
Het |
| Vmn2r108 |
T |
A |
17: 20,701,338 (GRCm39) |
Y54F |
probably benign |
Het |
| Vps13b |
T |
C |
15: 35,640,780 (GRCm39) |
Y1382H |
probably damaging |
Het |
| Wdr72 |
T |
C |
9: 74,117,754 (GRCm39) |
I834T |
probably damaging |
Het |
| Zfp970 |
T |
A |
2: 177,167,085 (GRCm39) |
C220S |
probably damaging |
Het |
| Zkscan5 |
T |
G |
5: 145,156,899 (GRCm39) |
I467S |
probably benign |
Het |
|
| Other mutations in Adcy8 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00589:Adcy8
|
APN |
15 |
64,659,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00690:Adcy8
|
APN |
15 |
64,571,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00990:Adcy8
|
APN |
15 |
64,694,162 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL01083:Adcy8
|
APN |
15 |
64,659,191 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL01296:Adcy8
|
APN |
15 |
64,655,628 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01433:Adcy8
|
APN |
15 |
64,609,263 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL01584:Adcy8
|
APN |
15 |
64,687,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01729:Adcy8
|
APN |
15 |
64,678,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02023:Adcy8
|
APN |
15 |
64,694,069 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02420:Adcy8
|
APN |
15 |
64,659,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02613:Adcy8
|
APN |
15 |
64,655,833 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02662:Adcy8
|
APN |
15 |
64,618,744 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03180:Adcy8
|
APN |
15 |
64,655,799 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL03327:Adcy8
|
APN |
15 |
64,792,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
revolutionary
|
UTSW |
15 |
64,571,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
whirligig
|
UTSW |
15 |
64,571,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F0336:Adcy8
|
UTSW |
15 |
64,694,083 (GRCm39) |
missense |
probably benign |
0.38 |
|
K7894:Adcy8
|
UTSW |
15 |
64,694,083 (GRCm39) |
missense |
probably benign |
0.38 |
|
PIT4581001:Adcy8
|
UTSW |
15 |
64,626,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0035:Adcy8
|
UTSW |
15 |
64,571,217 (GRCm39) |
missense |
probably benign |
0.29 |
|
R0119:Adcy8
|
UTSW |
15 |
64,588,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0129:Adcy8
|
UTSW |
15 |
64,618,862 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0299:Adcy8
|
UTSW |
15 |
64,588,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0573:Adcy8
|
UTSW |
15 |
64,694,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0961:Adcy8
|
UTSW |
15 |
64,626,711 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1203:Adcy8
|
UTSW |
15 |
64,618,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1239:Adcy8
|
UTSW |
15 |
64,587,911 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1615:Adcy8
|
UTSW |
15 |
64,743,625 (GRCm39) |
missense |
probably benign |
0.25 |
|
R1881:Adcy8
|
UTSW |
15 |
64,678,503 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2013:Adcy8
|
UTSW |
15 |
64,639,727 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2014:Adcy8
|
UTSW |
15 |
64,639,727 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2015:Adcy8
|
UTSW |
15 |
64,639,727 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2164:Adcy8
|
UTSW |
15 |
64,792,783 (GRCm39) |
missense |
probably benign |
|
|
R2228:Adcy8
|
UTSW |
15 |
64,694,056 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2229:Adcy8
|
UTSW |
15 |
64,694,056 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R2241:Adcy8
|
UTSW |
15 |
64,571,230 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R3177:Adcy8
|
UTSW |
15 |
64,571,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3277:Adcy8
|
UTSW |
15 |
64,571,008 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3404:Adcy8
|
UTSW |
15 |
64,571,449 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3688:Adcy8
|
UTSW |
15 |
64,743,556 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3709:Adcy8
|
UTSW |
15 |
64,597,384 (GRCm39) |
splice site |
probably benign |
|
|
R3710:Adcy8
|
UTSW |
15 |
64,597,384 (GRCm39) |
splice site |
probably benign |
|
|
R3778:Adcy8
|
UTSW |
15 |
64,618,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4037:Adcy8
|
UTSW |
15 |
64,597,319 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4685:Adcy8
|
UTSW |
15 |
64,609,287 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4731:Adcy8
|
UTSW |
15 |
64,626,711 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4732:Adcy8
|
UTSW |
15 |
64,626,711 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4733:Adcy8
|
UTSW |
15 |
64,626,711 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5071:Adcy8
|
UTSW |
15 |
64,659,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5073:Adcy8
|
UTSW |
15 |
64,659,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5074:Adcy8
|
UTSW |
15 |
64,659,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5091:Adcy8
|
UTSW |
15 |
64,678,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5285:Adcy8
|
UTSW |
15 |
64,639,706 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R5287:Adcy8
|
UTSW |
15 |
64,588,001 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5403:Adcy8
|
UTSW |
15 |
64,588,001 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5521:Adcy8
|
UTSW |
15 |
64,687,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5633:Adcy8
|
UTSW |
15 |
64,571,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5712:Adcy8
|
UTSW |
15 |
64,626,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5745:Adcy8
|
UTSW |
15 |
64,792,320 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5787:Adcy8
|
UTSW |
15 |
64,576,067 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5839:Adcy8
|
UTSW |
15 |
64,588,031 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5890:Adcy8
|
UTSW |
15 |
64,687,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6156:Adcy8
|
UTSW |
15 |
64,689,488 (GRCm39) |
splice site |
probably null |
|
|
R6338:Adcy8
|
UTSW |
15 |
64,792,466 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6516:Adcy8
|
UTSW |
15 |
64,571,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6525:Adcy8
|
UTSW |
15 |
64,609,243 (GRCm39) |
nonsense |
probably null |
|
|
R6636:Adcy8
|
UTSW |
15 |
64,659,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6823:Adcy8
|
UTSW |
15 |
64,626,735 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7007:Adcy8
|
UTSW |
15 |
64,576,565 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7070:Adcy8
|
UTSW |
15 |
64,792,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7371:Adcy8
|
UTSW |
15 |
64,571,067 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7457:Adcy8
|
UTSW |
15 |
64,792,529 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7611:Adcy8
|
UTSW |
15 |
64,792,882 (GRCm39) |
missense |
probably benign |
|
|
R7644:Adcy8
|
UTSW |
15 |
64,571,218 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7697:Adcy8
|
UTSW |
15 |
64,618,850 (GRCm39) |
missense |
probably benign |
|
|
R7735:Adcy8
|
UTSW |
15 |
64,655,629 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7789:Adcy8
|
UTSW |
15 |
64,743,623 (GRCm39) |
nonsense |
probably null |
|
|
R7860:Adcy8
|
UTSW |
15 |
64,571,322 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7894:Adcy8
|
UTSW |
15 |
64,792,054 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R7948:Adcy8
|
UTSW |
15 |
64,687,199 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7966:Adcy8
|
UTSW |
15 |
64,573,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8024:Adcy8
|
UTSW |
15 |
64,792,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8097:Adcy8
|
UTSW |
15 |
64,743,711 (GRCm39) |
splice site |
probably null |
|
|
R8158:Adcy8
|
UTSW |
15 |
64,655,655 (GRCm39) |
missense |
probably benign |
0.32 |
|
R8463:Adcy8
|
UTSW |
15 |
64,792,874 (GRCm39) |
missense |
probably benign |
|
|
R8474:Adcy8
|
UTSW |
15 |
64,576,638 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8696:Adcy8
|
UTSW |
15 |
64,687,235 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8955:Adcy8
|
UTSW |
15 |
64,576,554 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8973:Adcy8
|
UTSW |
15 |
64,570,984 (GRCm39) |
makesense |
probably null |
|
|
R9015:Adcy8
|
UTSW |
15 |
64,597,206 (GRCm39) |
intron |
probably benign |
|
|
R9041:Adcy8
|
UTSW |
15 |
64,609,287 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9052:Adcy8
|
UTSW |
15 |
64,792,764 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9074:Adcy8
|
UTSW |
15 |
64,573,940 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9183:Adcy8
|
UTSW |
15 |
64,694,116 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9259:Adcy8
|
UTSW |
15 |
64,576,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9498:Adcy8
|
UTSW |
15 |
64,792,045 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9522:Adcy8
|
UTSW |
15 |
64,792,560 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9800:Adcy8
|
UTSW |
15 |
64,571,095 (GRCm39) |
missense |
probably benign |
0.19 |
|
Z1176:Adcy8
|
UTSW |
15 |
64,597,367 (GRCm39) |
missense |
probably benign |
0.16 |
|
Z1177:Adcy8
|
UTSW |
15 |
64,571,026 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACACTCAGAGCAGAATGTGTTTG -3'
(R):5'- GGGCAGAACAATGGCTCTTAG -3'
Sequencing Primer
(F):5'- TGTGTTTGAAAGGAATAAAGGGTCC -3'
(R):5'- GTGAAGATCATATGCCCTCGTACAG -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation