Incidental Mutation 'R7096:Pcnx3'
| ID |
550526 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcnx3
|
| Ensembl Gene |
ENSMUSG00000054874 |
| Gene Name |
pecanex homolog 3 |
| Synonyms |
Pcnxl3 |
| MMRRC Submission |
045188-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7096 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
19 |
| Chromosomal Location |
5714663-5738936 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 5722643 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Cysteine
at position 1350
(R1350C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109245
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068169]
[ENSMUST00000113615]
|
| AlphaFold |
Q8VI59 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000068169
AA Change: R942C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000063786
Gene: ENSMUSG00000054874
AA Change: R942C
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
370 |
376 |
N/A |
INTRINSIC |
|
transmembrane domain
|
385 |
407 |
N/A |
INTRINSIC |
|
transmembrane domain
|
411 |
428 |
N/A |
INTRINSIC |
|
transmembrane domain
|
441 |
463 |
N/A |
INTRINSIC |
|
transmembrane domain
|
473 |
492 |
N/A |
INTRINSIC |
|
transmembrane domain
|
501 |
523 |
N/A |
INTRINSIC |
|
transmembrane domain
|
538 |
560 |
N/A |
INTRINSIC |
|
transmembrane domain
|
573 |
592 |
N/A |
INTRINSIC |
|
transmembrane domain
|
645 |
667 |
N/A |
INTRINSIC |
|
transmembrane domain
|
669 |
691 |
N/A |
INTRINSIC |
|
low complexity region
|
1011 |
1025 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1159 |
1389 |
7.5e-124 |
PFAM |
|
low complexity region
|
1462 |
1479 |
N/A |
INTRINSIC |
|
low complexity region
|
1481 |
1510 |
N/A |
INTRINSIC |
|
low complexity region
|
1525 |
1538 |
N/A |
INTRINSIC |
|
low complexity region
|
1558 |
1569 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113615
AA Change: R1350C
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000109245
Gene: ENSMUSG00000054874
AA Change: R1350C
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
36 |
53 |
N/A |
INTRINSIC |
|
transmembrane domain
|
57 |
79 |
N/A |
INTRINSIC |
|
low complexity region
|
99 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
438 |
459 |
N/A |
INTRINSIC |
|
low complexity region
|
778 |
784 |
N/A |
INTRINSIC |
|
transmembrane domain
|
793 |
815 |
N/A |
INTRINSIC |
|
transmembrane domain
|
819 |
836 |
N/A |
INTRINSIC |
|
transmembrane domain
|
849 |
871 |
N/A |
INTRINSIC |
|
transmembrane domain
|
881 |
900 |
N/A |
INTRINSIC |
|
transmembrane domain
|
909 |
931 |
N/A |
INTRINSIC |
|
transmembrane domain
|
946 |
968 |
N/A |
INTRINSIC |
|
transmembrane domain
|
981 |
1000 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1053 |
1075 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1077 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1419 |
1433 |
N/A |
INTRINSIC |
|
Pfam:Pecanex_C
|
1570 |
1796 |
5.9e-116 |
PFAM |
|
low complexity region
|
1870 |
1887 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1918 |
N/A |
INTRINSIC |
|
low complexity region
|
1933 |
1946 |
N/A |
INTRINSIC |
|
low complexity region
|
1966 |
1977 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000137313
|
| SMART Domains |
Protein: ENSMUSP00000115217
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
23 |
N/A |
INTRINSIC |
|
transmembrane domain
|
44 |
66 |
N/A |
INTRINSIC |
|
transmembrane domain
|
79 |
98 |
N/A |
INTRINSIC |
|
transmembrane domain
|
151 |
173 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145270
|
| SMART Domains |
Protein: ENSMUSP00000116493
Gene: ENSMUSG00000054874
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
199 |
205 |
N/A |
INTRINSIC |
|
transmembrane domain
|
214 |
236 |
N/A |
INTRINSIC |
|
transmembrane domain
|
240 |
257 |
N/A |
INTRINSIC |
|
transmembrane domain
|
270 |
292 |
N/A |
INTRINSIC |
|
transmembrane domain
|
302 |
321 |
N/A |
INTRINSIC |
|
transmembrane domain
|
330 |
352 |
N/A |
INTRINSIC |
|
transmembrane domain
|
367 |
389 |
N/A |
INTRINSIC |
|
transmembrane domain
|
402 |
421 |
N/A |
INTRINSIC |
|
transmembrane domain
|
474 |
496 |
N/A |
INTRINSIC |
|
transmembrane domain
|
498 |
520 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.5473 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
97% (68/70) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abhd18 |
T |
G |
3: 40,888,305 (GRCm39) |
M383R |
probably damaging |
Het |
| Acd |
T |
A |
8: 106,425,121 (GRCm39) |
E366V |
possibly damaging |
Het |
| Acvr2b |
T |
A |
9: 119,257,255 (GRCm39) |
|
probably null |
Het |
| Alg10b |
C |
T |
15: 90,111,564 (GRCm39) |
T136I |
probably benign |
Het |
| Ankrd42 |
T |
A |
7: 92,241,040 (GRCm39) |
K440* |
probably null |
Het |
| Apc |
T |
A |
18: 34,449,010 (GRCm39) |
S1969T |
probably damaging |
Het |
| Arhgef25 |
T |
C |
10: 127,019,897 (GRCm39) |
Y447C |
probably damaging |
Het |
| AW146154 |
G |
A |
7: 41,130,867 (GRCm39) |
A83V |
probably benign |
Het |
| Bach1 |
G |
A |
16: 87,516,179 (GRCm39) |
R240Q |
probably benign |
Het |
| Barhl1 |
T |
G |
2: 28,799,726 (GRCm39) |
I300L |
probably benign |
Het |
| Brd1 |
C |
A |
15: 88,598,138 (GRCm39) |
R536L |
probably damaging |
Het |
| Brms1 |
T |
A |
19: 5,096,708 (GRCm39) |
I130N |
probably damaging |
Het |
| Ccdc68 |
A |
G |
18: 70,073,241 (GRCm39) |
H63R |
probably damaging |
Het |
| Ccl28 |
A |
G |
13: 120,112,429 (GRCm39) |
I74V |
probably benign |
Het |
| Cd300ld |
T |
A |
11: 114,878,321 (GRCm39) |
I64F |
possibly damaging |
Het |
| Cdkl2 |
G |
A |
5: 92,181,043 (GRCm39) |
Q199* |
probably null |
Het |
| Cdkn2c |
C |
T |
4: 109,518,555 (GRCm39) |
R133Q |
probably benign |
Het |
| Coq2 |
A |
G |
5: 100,811,586 (GRCm39) |
|
probably benign |
Het |
| Coq6 |
T |
C |
12: 84,408,595 (GRCm39) |
|
probably null |
Het |
| Csmd2 |
C |
T |
4: 128,356,519 (GRCm39) |
S1608L |
|
Het |
| Cyp11b2 |
T |
A |
15: 74,727,837 (GRCm39) |
R82W |
probably damaging |
Het |
| Cyp2d10 |
T |
C |
15: 82,289,462 (GRCm39) |
T217A |
probably benign |
Het |
| Dclk2 |
C |
T |
3: 86,700,566 (GRCm39) |
R638H |
probably damaging |
Het |
| Dnah7a |
T |
C |
1: 53,522,599 (GRCm39) |
I2880V |
possibly damaging |
Het |
| Dync1h1 |
C |
A |
12: 110,623,512 (GRCm39) |
T3595K |
probably damaging |
Het |
| Ecscr |
T |
A |
18: 35,848,478 (GRCm39) |
E183V |
probably damaging |
Het |
| Elovl6 |
A |
G |
3: 129,398,755 (GRCm39) |
N52S |
probably benign |
Het |
| Eps8l1 |
G |
T |
7: 4,477,190 (GRCm39) |
A455S |
probably benign |
Het |
| Gpat2 |
A |
G |
2: 127,270,209 (GRCm39) |
N74S |
probably benign |
Het |
| Gstk1 |
C |
A |
6: 42,226,407 (GRCm39) |
T172K |
probably damaging |
Het |
| Gtf3c1 |
T |
C |
7: 125,295,731 (GRCm39) |
|
probably null |
Het |
| Gucy2c |
T |
C |
6: 136,705,339 (GRCm39) |
D532G |
probably benign |
Het |
| Hoxc12 |
T |
A |
15: 102,845,473 (GRCm39) |
N62K |
possibly damaging |
Het |
| Hsdl1 |
C |
A |
8: 120,293,064 (GRCm39) |
A124S |
possibly damaging |
Het |
| Il11 |
T |
C |
7: 4,778,995 (GRCm39) |
Y45C |
probably damaging |
Het |
| Lcat |
C |
T |
8: 106,666,309 (GRCm39) |
M404I |
possibly damaging |
Het |
| Ldhb |
A |
G |
6: 142,447,099 (GRCm39) |
F72L |
probably benign |
Het |
| Map10 |
T |
C |
8: 126,398,662 (GRCm39) |
L685P |
probably damaging |
Het |
| Me2 |
A |
G |
18: 73,927,961 (GRCm39) |
V174A |
probably benign |
Het |
| Med13l |
C |
A |
5: 118,859,991 (GRCm39) |
Q328K |
possibly damaging |
Het |
| Mta2 |
A |
T |
19: 8,925,139 (GRCm39) |
I336F |
probably damaging |
Het |
| Mterf1a |
A |
T |
5: 3,941,769 (GRCm39) |
I33N |
probably damaging |
Het |
| Myo15b |
T |
A |
11: 115,782,324 (GRCm39) |
|
probably null |
Het |
| Myof |
C |
A |
19: 37,924,648 (GRCm39) |
G1215V |
probably damaging |
Het |
| Nlgn2 |
G |
A |
11: 69,716,516 (GRCm39) |
T675M |
probably damaging |
Het |
| Or1e26 |
T |
A |
11: 73,480,463 (GRCm39) |
M34L |
probably benign |
Het |
| Or5p61 |
C |
A |
7: 107,758,848 (GRCm39) |
M77I |
probably benign |
Het |
| Or6c38 |
T |
C |
10: 128,929,715 (GRCm39) |
I43V |
probably damaging |
Het |
| Padi3 |
T |
C |
4: 140,527,435 (GRCm39) |
D122G |
probably damaging |
Het |
| Pdzrn4 |
C |
A |
15: 92,295,384 (GRCm39) |
Q197K |
probably benign |
Het |
| Pitpnm2 |
C |
T |
5: 124,267,324 (GRCm39) |
G639S |
possibly damaging |
Het |
| Piwil4 |
T |
A |
9: 14,648,112 (GRCm39) |
K156* |
probably null |
Het |
| Pkmyt1 |
T |
A |
17: 23,953,087 (GRCm39) |
H214Q |
probably damaging |
Het |
| Pnpt1 |
G |
A |
11: 29,104,867 (GRCm39) |
R597Q |
probably benign |
Het |
| Poteg |
C |
A |
8: 27,963,595 (GRCm39) |
A344E |
probably benign |
Het |
| Rad21l |
A |
G |
2: 151,509,840 (GRCm39) |
M87T |
probably benign |
Het |
| Ranbp17 |
T |
C |
11: 33,424,896 (GRCm39) |
I487V |
probably benign |
Het |
| Rap1gap2 |
C |
A |
11: 74,283,057 (GRCm39) |
R681L |
probably damaging |
Het |
| Rimbp2 |
C |
A |
5: 128,851,333 (GRCm39) |
R871L |
probably damaging |
Het |
| Rnf135 |
T |
C |
11: 80,080,051 (GRCm39) |
V114A |
probably benign |
Het |
| Skic2 |
T |
A |
17: 35,060,446 (GRCm39) |
H849L |
probably benign |
Het |
| Snai2 |
A |
G |
16: 14,525,028 (GRCm39) |
H178R |
possibly damaging |
Het |
| Stip1 |
C |
T |
19: 6,999,178 (GRCm39) |
G467S |
possibly damaging |
Het |
| Taar1 |
A |
T |
10: 23,796,809 (GRCm39) |
E169V |
possibly damaging |
Het |
| Tdrd12 |
G |
T |
7: 35,187,014 (GRCm39) |
D625E |
|
Het |
| Tlr6 |
A |
G |
5: 65,111,119 (GRCm39) |
V596A |
probably benign |
Het |
| Trak2 |
T |
G |
1: 58,942,749 (GRCm39) |
N886H |
probably damaging |
Het |
| Tsga10 |
T |
A |
1: 37,879,695 (GRCm39) |
D32V |
probably damaging |
Het |
| Vmn1r214 |
A |
G |
13: 23,219,196 (GRCm39) |
D230G |
probably damaging |
Het |
| Vmn2r108 |
A |
G |
17: 20,682,762 (GRCm39) |
L814S |
probably damaging |
Het |
| Zbbx |
T |
C |
3: 74,989,044 (GRCm39) |
D353G |
probably benign |
Het |
|
| Other mutations in Pcnx3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01616:Pcnx3
|
APN |
19 |
5,717,287 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01667:Pcnx3
|
APN |
19 |
5,736,658 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01704:Pcnx3
|
APN |
19 |
5,717,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01752:Pcnx3
|
APN |
19 |
5,715,365 (GRCm39) |
nonsense |
probably null |
|
|
IGL01791:Pcnx3
|
APN |
19 |
5,723,295 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL01937:Pcnx3
|
APN |
19 |
5,727,691 (GRCm39) |
missense |
probably benign |
|
|
IGL01987:Pcnx3
|
APN |
19 |
5,727,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02073:Pcnx3
|
APN |
19 |
5,729,414 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02417:Pcnx3
|
APN |
19 |
5,736,509 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03143:Pcnx3
|
APN |
19 |
5,735,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
buns
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
Pastries
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
pie
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7096_pcnx3_526
|
UTSW |
19 |
5,722,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
swirls
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
tip
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
PIT4453001:Pcnx3
|
UTSW |
19 |
5,722,784 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0234:Pcnx3
|
UTSW |
19 |
5,722,646 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0360:Pcnx3
|
UTSW |
19 |
5,715,611 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0687:Pcnx3
|
UTSW |
19 |
5,734,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0718:Pcnx3
|
UTSW |
19 |
5,727,756 (GRCm39) |
splice site |
probably benign |
|
|
R0840:Pcnx3
|
UTSW |
19 |
5,735,729 (GRCm39) |
splice site |
probably null |
|
|
R0907:Pcnx3
|
UTSW |
19 |
5,721,553 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1251:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1373:Pcnx3
|
UTSW |
19 |
5,715,544 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1467:Pcnx3
|
UTSW |
19 |
5,724,922 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R1572:Pcnx3
|
UTSW |
19 |
5,735,375 (GRCm39) |
nonsense |
probably null |
|
|
R1602:Pcnx3
|
UTSW |
19 |
5,722,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1628:Pcnx3
|
UTSW |
19 |
5,736,093 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1635:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1670:Pcnx3
|
UTSW |
19 |
5,723,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Pcnx3
|
UTSW |
19 |
5,722,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1898:Pcnx3
|
UTSW |
19 |
5,722,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2113:Pcnx3
|
UTSW |
19 |
5,721,584 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2147:Pcnx3
|
UTSW |
19 |
5,717,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R2358:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R2871:Pcnx3
|
UTSW |
19 |
5,733,774 (GRCm39) |
intron |
probably benign |
|
|
R3699:Pcnx3
|
UTSW |
19 |
5,722,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,368 (GRCm39) |
start codon destroyed |
probably null |
|
|
R3712:Pcnx3
|
UTSW |
19 |
5,733,367 (GRCm39) |
nonsense |
probably null |
|
|
R3798:Pcnx3
|
UTSW |
19 |
5,728,696 (GRCm39) |
nonsense |
probably null |
|
|
R3856:Pcnx3
|
UTSW |
19 |
5,728,995 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3953:Pcnx3
|
UTSW |
19 |
5,733,808 (GRCm39) |
splice site |
probably benign |
|
|
R4613:Pcnx3
|
UTSW |
19 |
5,717,247 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4781:Pcnx3
|
UTSW |
19 |
5,737,158 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4816:Pcnx3
|
UTSW |
19 |
5,738,023 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5338:Pcnx3
|
UTSW |
19 |
5,722,624 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5770:Pcnx3
|
UTSW |
19 |
5,731,607 (GRCm39) |
intron |
probably benign |
|
|
R5950:Pcnx3
|
UTSW |
19 |
5,717,186 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5951:Pcnx3
|
UTSW |
19 |
5,721,708 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R5969:Pcnx3
|
UTSW |
19 |
5,735,563 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6543:Pcnx3
|
UTSW |
19 |
5,715,275 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6704:Pcnx3
|
UTSW |
19 |
5,736,515 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7177:Pcnx3
|
UTSW |
19 |
5,737,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7308:Pcnx3
|
UTSW |
19 |
5,736,175 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R7387:Pcnx3
|
UTSW |
19 |
5,723,364 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7488:Pcnx3
|
UTSW |
19 |
5,717,487 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7670:Pcnx3
|
UTSW |
19 |
5,727,210 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7831:Pcnx3
|
UTSW |
19 |
5,735,989 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7850:Pcnx3
|
UTSW |
19 |
5,728,960 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8120:Pcnx3
|
UTSW |
19 |
5,717,574 (GRCm39) |
missense |
probably benign |
|
|
R8139:Pcnx3
|
UTSW |
19 |
5,715,773 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8258:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8259:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8262:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8411:Pcnx3
|
UTSW |
19 |
5,729,618 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8429:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8431:Pcnx3
|
UTSW |
19 |
5,715,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8443:Pcnx3
|
UTSW |
19 |
5,736,670 (GRCm39) |
missense |
probably benign |
|
|
R8450:Pcnx3
|
UTSW |
19 |
5,723,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Pcnx3
|
UTSW |
19 |
5,725,404 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8790:Pcnx3
|
UTSW |
19 |
5,735,206 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8939:Pcnx3
|
UTSW |
19 |
5,730,347 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9065:Pcnx3
|
UTSW |
19 |
5,717,582 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9070:Pcnx3
|
UTSW |
19 |
5,715,601 (GRCm39) |
missense |
probably benign |
0.33 |
|
X0028:Pcnx3
|
UTSW |
19 |
5,734,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0053:Pcnx3
|
UTSW |
19 |
5,736,650 (GRCm39) |
splice site |
probably null |
|
|
Z1176:Pcnx3
|
UTSW |
19 |
5,737,248 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1177:Pcnx3
|
UTSW |
19 |
5,721,654 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAATCTTGTGTCCCAGCCCAG -3'
(R):5'- GGACCATTCTAACACTCGCCTAG -3'
Sequencing Primer
(F):5'- TGCTAGTCTCCCAGCTCAGG -3'
(R):5'- ACTCGCCTAGTGACACAGCTG -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation