Incidental Mutation 'R7144:Iqgap3'
| ID |
553612 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap3
|
| Ensembl Gene |
ENSMUSG00000028068 |
| Gene Name |
IQ motif containing GTPase activating protein 3 |
| Synonyms |
|
| MMRRC Submission |
045328-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.342)
|
| Stock # |
R7144 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
87989309-88028355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 88024217 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 1513
(I1513N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071715
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071812]
[ENSMUST00000194440]
|
| AlphaFold |
F8VQ29 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071812
AA Change: I1513N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000071715
Gene: ENSMUSG00000028068
AA Change: I1513N
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
1.72e-14 |
SMART |
|
internal_repeat_2
|
197 |
249 |
1.75e-5 |
PROSPERO |
|
internal_repeat_1
|
209 |
418 |
1.31e-14 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
651 |
1.31e-14 |
PROSPERO |
|
internal_repeat_2
|
600 |
652 |
1.75e-5 |
PROSPERO |
|
IQ
|
730 |
752 |
1.18e1 |
SMART |
|
IQ
|
760 |
782 |
3.76e-6 |
SMART |
|
IQ
|
790 |
812 |
3.08e-2 |
SMART |
|
IQ
|
820 |
842 |
1.72e0 |
SMART |
|
RasGAP
|
977 |
1330 |
1.74e-57 |
SMART |
|
Blast:RasGAP
|
1338 |
1422 |
1e-9 |
BLAST |
|
Pfam:RasGAP_C
|
1434 |
1555 |
2e-36 |
PFAM |
|
low complexity region
|
1591 |
1602 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1630 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000194440
AA Change: I615N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142035
Gene: ENSMUSG00000028068
AA Change: I615N
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RasGAP
|
1 |
67 |
3e-30 |
BLAST |
|
RasGAP
|
79 |
432 |
1e-59 |
SMART |
|
Blast:RasGAP
|
440 |
524 |
5e-10 |
BLAST |
|
Pfam:RasGAP_C
|
535 |
660 |
5.7e-30 |
PFAM |
|
low complexity region
|
693 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
732 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
99% (95/96) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca16 |
A |
T |
7: 120,032,796 (GRCm39) |
I272F |
possibly damaging |
Het |
| Adcy10 |
G |
T |
1: 165,337,939 (GRCm39) |
M184I |
probably benign |
Het |
| Aldoa |
G |
T |
7: 126,396,034 (GRCm39) |
T124N |
possibly damaging |
Het |
| Ap4e1 |
T |
A |
2: 126,853,727 (GRCm39) |
I55N |
probably damaging |
Het |
| Arhgap21 |
T |
C |
2: 20,870,198 (GRCm39) |
T913A |
probably benign |
Het |
| Atrnl1 |
G |
A |
19: 58,030,784 (GRCm39) |
E1309K |
probably damaging |
Het |
| BC034090 |
A |
T |
1: 155,117,777 (GRCm39) |
C114S |
probably damaging |
Het |
| Brinp2 |
A |
G |
1: 158,122,994 (GRCm39) |
|
probably null |
Het |
| Ccn4 |
T |
A |
15: 66,784,879 (GRCm39) |
V184E |
probably damaging |
Het |
| Ccna1 |
G |
T |
3: 54,953,120 (GRCm39) |
H408Q |
probably benign |
Het |
| Cd209g |
T |
G |
8: 4,185,189 (GRCm39) |
|
probably benign |
Het |
| Cdc20b |
A |
G |
13: 113,219,905 (GRCm39) |
I433V |
probably benign |
Het |
| Cdk2ap1 |
G |
A |
5: 124,492,421 (GRCm39) |
P5L |
probably damaging |
Het |
| Cep128 |
T |
C |
12: 91,260,933 (GRCm39) |
E310G |
probably damaging |
Het |
| Cflar |
G |
T |
1: 58,793,007 (GRCm39) |
V458F |
|
Het |
| Clec4b2 |
A |
G |
6: 123,158,343 (GRCm39) |
T70A |
probably benign |
Het |
| Cntnap5c |
A |
G |
17: 58,593,883 (GRCm39) |
T741A |
probably benign |
Het |
| Csf3r |
A |
T |
4: 125,937,515 (GRCm39) |
T800S |
probably benign |
Het |
| Csnk1g2 |
T |
C |
10: 80,473,733 (GRCm39) |
Y67H |
probably damaging |
Het |
| Cyp2c67 |
A |
T |
19: 39,604,138 (GRCm39) |
V406E |
probably benign |
Het |
| Dnah10 |
A |
G |
5: 124,900,006 (GRCm39) |
D3868G |
probably damaging |
Het |
| Dnah7a |
A |
T |
1: 53,737,867 (GRCm39) |
|
probably null |
Het |
| Dst |
A |
G |
1: 34,191,324 (GRCm39) |
N208S |
probably damaging |
Het |
| Echdc3 |
A |
G |
2: 6,211,224 (GRCm39) |
|
probably null |
Het |
| Edrf1 |
T |
C |
7: 133,239,578 (GRCm39) |
S13P |
probably benign |
Het |
| Ephb1 |
T |
C |
9: 101,841,276 (GRCm39) |
Y734C |
probably damaging |
Het |
| Eps8l1 |
A |
G |
7: 4,475,184 (GRCm39) |
Y325C |
probably damaging |
Het |
| Evc2 |
A |
G |
5: 37,544,183 (GRCm39) |
D644G |
probably damaging |
Het |
| Eya4 |
A |
C |
10: 23,048,943 (GRCm39) |
D54E |
probably benign |
Het |
| Filip1 |
T |
C |
9: 79,727,495 (GRCm39) |
S375G |
possibly damaging |
Het |
| Fmo9 |
A |
G |
1: 166,505,189 (GRCm39) |
M68T |
probably benign |
Het |
| Gemin5 |
G |
C |
11: 58,032,489 (GRCm39) |
P772A |
probably benign |
Het |
| Gle1 |
T |
G |
2: 29,833,805 (GRCm39) |
C401G |
probably damaging |
Het |
| Gm7298 |
A |
T |
6: 121,738,546 (GRCm39) |
I376F |
probably damaging |
Het |
| Gpr35 |
A |
C |
1: 92,910,353 (GRCm39) |
I22L |
probably benign |
Het |
| Grin2b |
T |
G |
6: 135,710,474 (GRCm39) |
D1024A |
possibly damaging |
Het |
| Hmcn1 |
T |
C |
1: 150,539,624 (GRCm39) |
N2956D |
probably damaging |
Het |
| Htt |
T |
C |
5: 35,003,350 (GRCm39) |
L1275P |
probably damaging |
Het |
| Ibtk |
T |
C |
9: 85,625,744 (GRCm39) |
D2G |
probably benign |
Het |
| Il16 |
T |
A |
7: 83,295,659 (GRCm39) |
D1170V |
probably damaging |
Het |
| Kiz |
T |
G |
2: 146,792,430 (GRCm39) |
|
probably null |
Het |
| Krt12 |
A |
T |
11: 99,306,839 (GRCm39) |
*488K |
probably null |
Het |
| Lap3 |
A |
T |
5: 45,654,290 (GRCm39) |
T83S |
probably benign |
Het |
| Lars2 |
T |
A |
9: 123,261,058 (GRCm39) |
S410T |
probably damaging |
Het |
| Limch1 |
A |
G |
5: 67,175,001 (GRCm39) |
T518A |
probably benign |
Het |
| Lrrc49 |
A |
T |
9: 60,522,439 (GRCm39) |
S381T |
probably damaging |
Het |
| Lrrk2 |
A |
G |
15: 91,618,258 (GRCm39) |
D919G |
possibly damaging |
Het |
| Mmp1a |
A |
T |
9: 7,475,319 (GRCm39) |
S363C |
probably damaging |
Het |
| Mrps22 |
A |
C |
9: 98,483,524 (GRCm39) |
|
probably null |
Het |
| Mybpc3 |
T |
C |
2: 90,964,949 (GRCm39) |
I1066T |
probably benign |
Het |
| Myo10 |
A |
T |
15: 25,724,011 (GRCm39) |
N215I |
probably damaging |
Het |
| Myocd |
A |
C |
11: 65,109,474 (GRCm39) |
L99R |
probably damaging |
Het |
| Nadk |
T |
G |
4: 155,673,793 (GRCm39) |
I394S |
probably damaging |
Het |
| Nadsyn1 |
T |
C |
7: 143,364,952 (GRCm39) |
N251S |
probably damaging |
Het |
| Nbeal1 |
G |
C |
1: 60,276,310 (GRCm39) |
V684L |
probably benign |
Het |
| Ncapd2 |
G |
A |
6: 125,153,633 (GRCm39) |
P694L |
probably benign |
Het |
| Or2ag1 |
T |
A |
7: 106,473,075 (GRCm39) |
I126F |
probably damaging |
Het |
| Or2w3b |
A |
C |
11: 58,623,571 (GRCm39) |
L140R |
probably damaging |
Het |
| Or4a71 |
T |
C |
2: 89,357,901 (GRCm39) |
I284M |
probably damaging |
Het |
| Or5t16 |
G |
T |
2: 86,819,164 (GRCm39) |
R119S |
probably damaging |
Het |
| Pcdhb13 |
T |
A |
18: 37,576,309 (GRCm39) |
I229K |
probably damaging |
Het |
| Pgbd5 |
A |
T |
8: 125,101,056 (GRCm39) |
M400K |
possibly damaging |
Het |
| Phactr3 |
A |
G |
2: 177,944,529 (GRCm39) |
N409S |
probably damaging |
Het |
| Pik3c2g |
C |
A |
6: 139,606,868 (GRCm39) |
P305Q |
probably damaging |
Het |
| Pik3r4 |
G |
A |
9: 105,527,783 (GRCm39) |
V379M |
probably damaging |
Het |
| Pira12 |
A |
G |
7: 3,900,615 (GRCm39) |
V45A |
probably damaging |
Het |
| Pkd1l2 |
A |
T |
8: 117,802,870 (GRCm39) |
C250* |
probably null |
Het |
| Pramel14 |
A |
C |
4: 143,718,103 (GRCm39) |
S447A |
probably benign |
Het |
| Rapgef6 |
A |
C |
11: 54,548,191 (GRCm39) |
T792P |
possibly damaging |
Het |
| Rexo5 |
A |
G |
7: 119,404,414 (GRCm39) |
D170G |
probably damaging |
Het |
| Rnf17 |
G |
A |
14: 56,749,789 (GRCm39) |
|
probably null |
Het |
| Septin11 |
A |
G |
5: 93,304,725 (GRCm39) |
I181V |
probably benign |
Het |
| Serpina1e |
T |
G |
12: 103,913,277 (GRCm39) |
*414C |
probably null |
Het |
| Serpine1 |
C |
A |
5: 137,099,918 (GRCm39) |
Q80H |
probably damaging |
Het |
| Sh3bp2 |
A |
G |
5: 34,718,975 (GRCm39) |
N560S |
probably benign |
Het |
| Slc25a25 |
A |
G |
2: 32,309,178 (GRCm39) |
F221S |
probably damaging |
Het |
| Spag17 |
G |
T |
3: 99,934,717 (GRCm39) |
|
probably null |
Het |
| Sspn |
T |
C |
6: 145,906,881 (GRCm39) |
L104P |
probably damaging |
Het |
| St18 |
A |
C |
1: 6,903,818 (GRCm39) |
E693A |
probably damaging |
Het |
| St6galnac3 |
T |
C |
3: 153,117,169 (GRCm39) |
I185V |
possibly damaging |
Het |
| St8sia1 |
T |
C |
6: 142,822,395 (GRCm39) |
D156G |
probably damaging |
Het |
| Syne2 |
C |
A |
12: 76,052,152 (GRCm39) |
S4092R |
probably benign |
Het |
| Tll1 |
T |
A |
8: 64,577,979 (GRCm39) |
D76V |
possibly damaging |
Het |
| Tmco1 |
C |
T |
1: 167,136,022 (GRCm39) |
|
probably benign |
Het |
| Tnfaip3 |
T |
A |
10: 18,883,029 (GRCm39) |
T179S |
probably benign |
Het |
| Trav16 |
T |
C |
14: 53,981,096 (GRCm39) |
I95T |
possibly damaging |
Het |
| Trip12 |
A |
T |
1: 84,771,435 (GRCm39) |
S280T |
probably damaging |
Het |
| Unc79 |
A |
G |
12: 103,108,885 (GRCm39) |
M2166V |
probably benign |
Het |
| Vmn2r1 |
A |
G |
3: 63,997,362 (GRCm39) |
I339M |
probably damaging |
Het |
| Vwa5b1 |
A |
G |
4: 138,332,742 (GRCm39) |
|
probably null |
Het |
| Washc4 |
A |
T |
10: 83,409,638 (GRCm39) |
|
probably null |
Het |
| Wiz |
A |
G |
17: 32,576,602 (GRCm39) |
S642P |
possibly damaging |
Het |
| Zeb2 |
T |
A |
2: 45,000,053 (GRCm39) |
K60N |
possibly damaging |
Het |
| Zfat |
T |
A |
15: 68,050,631 (GRCm39) |
T797S |
probably benign |
Het |
| Zfp74 |
T |
C |
7: 29,634,590 (GRCm39) |
K373E |
probably damaging |
Het |
| Zswim5 |
T |
C |
4: 116,833,173 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Iqgap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Iqgap3
|
APN |
3 |
88,014,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Iqgap3
|
APN |
3 |
88,017,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01517:Iqgap3
|
APN |
3 |
88,016,703 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01530:Iqgap3
|
APN |
3 |
88,019,610 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01658:Iqgap3
|
APN |
3 |
88,023,278 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02027:Iqgap3
|
APN |
3 |
87,994,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02352:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02359:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02522:Iqgap3
|
APN |
3 |
88,015,705 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02717:Iqgap3
|
APN |
3 |
88,005,666 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02971:Iqgap3
|
APN |
3 |
87,997,611 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03079:Iqgap3
|
APN |
3 |
88,020,477 (GRCm39) |
missense |
probably benign |
|
|
IGL03240:Iqgap3
|
APN |
3 |
88,022,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
adjutant
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Booster
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
peso_ligero
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0285:Iqgap3
|
UTSW |
3 |
88,004,297 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0442:Iqgap3
|
UTSW |
3 |
88,023,266 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0490:Iqgap3
|
UTSW |
3 |
88,021,363 (GRCm39) |
splice site |
probably benign |
|
|
R0569:Iqgap3
|
UTSW |
3 |
87,998,032 (GRCm39) |
splice site |
probably benign |
|
|
R0747:Iqgap3
|
UTSW |
3 |
88,014,810 (GRCm39) |
splice site |
probably benign |
|
|
R0843:Iqgap3
|
UTSW |
3 |
88,015,738 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1260:Iqgap3
|
UTSW |
3 |
88,021,330 (GRCm39) |
missense |
probably benign |
|
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1662:Iqgap3
|
UTSW |
3 |
88,005,708 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1686:Iqgap3
|
UTSW |
3 |
88,015,663 (GRCm39) |
splice site |
probably benign |
|
|
R1748:Iqgap3
|
UTSW |
3 |
88,021,287 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1836:Iqgap3
|
UTSW |
3 |
88,015,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R1973:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R2051:Iqgap3
|
UTSW |
3 |
88,027,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Iqgap3
|
UTSW |
3 |
88,023,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2352:Iqgap3
|
UTSW |
3 |
88,011,815 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2857:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R2859:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R3435:Iqgap3
|
UTSW |
3 |
88,001,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3522:Iqgap3
|
UTSW |
3 |
87,998,089 (GRCm39) |
missense |
probably null |
0.90 |
|
R4281:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4283:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4397:Iqgap3
|
UTSW |
3 |
88,011,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4414:Iqgap3
|
UTSW |
3 |
88,004,293 (GRCm39) |
missense |
probably benign |
|
|
R4660:Iqgap3
|
UTSW |
3 |
88,027,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4872:Iqgap3
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Iqgap3
|
UTSW |
3 |
88,014,842 (GRCm39) |
missense |
probably benign |
|
|
R4915:Iqgap3
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5050:Iqgap3
|
UTSW |
3 |
87,997,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Iqgap3
|
UTSW |
3 |
88,016,161 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5151:Iqgap3
|
UTSW |
3 |
88,025,067 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5645:Iqgap3
|
UTSW |
3 |
88,025,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5706:Iqgap3
|
UTSW |
3 |
88,023,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5748:Iqgap3
|
UTSW |
3 |
88,016,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5880:Iqgap3
|
UTSW |
3 |
88,024,509 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5982:Iqgap3
|
UTSW |
3 |
87,998,899 (GRCm39) |
nonsense |
probably null |
|
|
R6006:Iqgap3
|
UTSW |
3 |
87,998,854 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6026:Iqgap3
|
UTSW |
3 |
87,997,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6188:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6211:Iqgap3
|
UTSW |
3 |
87,998,822 (GRCm39) |
missense |
probably benign |
|
|
R6291:Iqgap3
|
UTSW |
3 |
87,997,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6344:Iqgap3
|
UTSW |
3 |
87,989,401 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6854:Iqgap3
|
UTSW |
3 |
88,004,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6877:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6958:Iqgap3
|
UTSW |
3 |
88,020,673 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7008:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R7050:Iqgap3
|
UTSW |
3 |
88,006,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7170:Iqgap3
|
UTSW |
3 |
88,009,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Iqgap3
|
UTSW |
3 |
88,016,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Iqgap3
|
UTSW |
3 |
88,005,677 (GRCm39) |
missense |
probably benign |
|
|
R8008:Iqgap3
|
UTSW |
3 |
88,016,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8049:Iqgap3
|
UTSW |
3 |
88,011,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Iqgap3
|
UTSW |
3 |
88,001,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8190:Iqgap3
|
UTSW |
3 |
87,998,086 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8772:Iqgap3
|
UTSW |
3 |
87,997,144 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8878:Iqgap3
|
UTSW |
3 |
88,020,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Iqgap3
|
UTSW |
3 |
87,997,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9072:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9072:Iqgap3
|
UTSW |
3 |
87,998,883 (GRCm39) |
missense |
probably benign |
|
|
R9073:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9337:Iqgap3
|
UTSW |
3 |
88,023,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9489:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9492:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9593:Iqgap3
|
UTSW |
3 |
88,011,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Iqgap3
|
UTSW |
3 |
88,016,728 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9708:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9709:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Iqgap3
|
UTSW |
3 |
88,017,361 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9771:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9772:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Iqgap3
|
UTSW |
3 |
87,996,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTCTTGAATGTCCTCACAGTAAGC -3'
(R):5'- GAGGTGATCTGGAACCACAG -3'
Sequencing Primer
(F):5'- GAATGTCCTCACAGTAAGCCTTGTG -3'
(R):5'- CACAGACACCAGGGTCAGG -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation