Incidental Mutation 'R7146:Abca14'
| ID |
553789 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abca14
|
| Ensembl Gene |
ENSMUSG00000062017 |
| Gene Name |
ATP-binding cassette, sub-family A member 14 |
| Synonyms |
1700110B15Rik, 4930539G24Rik |
| MMRRC Submission |
045251-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7146 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
119803184-119924575 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 119854520 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 895
(I895F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000081690
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000084640]
|
| AlphaFold |
E9Q8F8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000084640
AA Change: I895F
PolyPhen 2
Score 0.146 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000081690
Gene: ENSMUSG00000062017
AA Change: I895F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC2_membrane_3
|
24 |
463 |
5.7e-23 |
PFAM |
|
AAA
|
548 |
729 |
1.59e-10 |
SMART |
|
Pfam:ABC2_membrane_3
|
902 |
1296 |
1.2e-36 |
PFAM |
|
AAA
|
1384 |
1568 |
1.33e-3 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.2%
|
| Validation Efficiency |
95% (99/104) |
| Allele List at MGI |
All alleles(1) : Gene trapped(1)
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca16 |
A |
G |
7: 120,126,974 (GRCm39) |
N1222D |
possibly damaging |
Het |
| Abcc4 |
A |
T |
14: 118,852,593 (GRCm39) |
Y499N |
probably damaging |
Het |
| Adgrg7 |
A |
C |
16: 56,550,605 (GRCm39) |
C702W |
probably damaging |
Het |
| Adk |
C |
A |
14: 21,376,682 (GRCm39) |
P27H |
|
Het |
| Ankrd13a |
T |
C |
5: 114,913,293 (GRCm39) |
S2P |
probably damaging |
Het |
| Ano1 |
T |
C |
7: 144,209,393 (GRCm39) |
H269R |
probably benign |
Het |
| Aox3 |
T |
A |
1: 58,197,688 (GRCm39) |
|
probably null |
Het |
| Asl |
G |
A |
5: 130,053,290 (GRCm39) |
|
probably benign |
Het |
| Asxl2 |
A |
T |
12: 3,507,066 (GRCm39) |
D86V |
probably damaging |
Het |
| Ate1 |
A |
T |
7: 130,083,508 (GRCm39) |
|
probably null |
Het |
| Bach2 |
A |
G |
4: 32,562,670 (GRCm39) |
D379G |
probably damaging |
Het |
| Bdkrb1 |
T |
A |
12: 105,571,142 (GRCm39) |
L236Q |
probably damaging |
Het |
| Cacna2d3 |
T |
C |
14: 29,443,654 (GRCm39) |
Y24C |
unknown |
Het |
| Cage1 |
G |
T |
13: 38,207,025 (GRCm39) |
N273K |
probably benign |
Het |
| Ccdc51 |
T |
A |
9: 108,920,848 (GRCm39) |
I245N |
probably damaging |
Het |
| Cep152 |
T |
C |
2: 125,456,325 (GRCm39) |
I229V |
probably benign |
Het |
| Chst4 |
T |
A |
8: 110,757,363 (GRCm39) |
S167C |
probably damaging |
Het |
| Cntnap4 |
A |
T |
8: 113,537,268 (GRCm39) |
Y713F |
probably damaging |
Het |
| Cntnap5b |
G |
A |
1: 99,978,519 (GRCm39) |
|
probably null |
Het |
| Cog8 |
G |
T |
8: 107,779,005 (GRCm39) |
T424K |
possibly damaging |
Het |
| Cop1 |
T |
G |
1: 159,071,922 (GRCm39) |
|
probably null |
Het |
| Cyp2j6 |
A |
G |
4: 96,434,019 (GRCm39) |
I97T |
probably damaging |
Het |
| D430041D05Rik |
T |
C |
2: 104,088,698 (GRCm39) |
T131A |
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,972,936 (GRCm39) |
D1999G |
probably damaging |
Het |
| Dnah8 |
A |
G |
17: 30,863,591 (GRCm39) |
D250G |
probably benign |
Het |
| Dnah8 |
T |
C |
17: 30,988,618 (GRCm39) |
V3196A |
possibly damaging |
Het |
| Dscam |
A |
T |
16: 96,631,117 (GRCm39) |
Y299* |
probably null |
Het |
| Efcab3 |
A |
G |
11: 104,858,578 (GRCm39) |
N3879S |
unknown |
Het |
| Efcab3 |
A |
C |
11: 104,913,764 (GRCm39) |
D4594A |
probably benign |
Het |
| Ephb1 |
A |
G |
9: 101,841,157 (GRCm39) |
S774P |
probably damaging |
Het |
| Fat1 |
G |
A |
8: 45,403,962 (GRCm39) |
V238I |
probably benign |
Het |
| Fermt1 |
C |
T |
2: 132,776,785 (GRCm39) |
M234I |
probably benign |
Het |
| Fmnl2 |
C |
T |
2: 52,958,552 (GRCm39) |
S212L |
|
Het |
| Frem1 |
T |
C |
4: 82,840,532 (GRCm39) |
N1798S |
possibly damaging |
Het |
| Gabrd |
T |
A |
4: 155,469,863 (GRCm39) |
M449L |
probably benign |
Het |
| Gad1 |
T |
C |
2: 70,417,706 (GRCm39) |
F302L |
probably benign |
Het |
| Gm10800 |
A |
AC |
2: 98,497,378 (GRCm39) |
|
probably null |
Het |
| Gm21886 |
GGGCCTGCAGACAGTAGGTGCTCACTAGGGCCTGTAAATAGTAGGTGCTCACTGAGGCCTGTAGACAGTAGGTGCTCA |
GGGCCTGTAGACAGTAGGTGCTCA |
18: 80,132,697 (GRCm39) |
|
probably benign |
Het |
| Gnb3 |
C |
T |
6: 124,813,887 (GRCm39) |
|
probably null |
Het |
| Gtf3c1 |
A |
T |
7: 125,271,993 (GRCm39) |
M642K |
possibly damaging |
Het |
| Hps3 |
A |
T |
3: 20,063,050 (GRCm39) |
W838R |
probably damaging |
Het |
| Ide |
A |
T |
19: 37,273,343 (GRCm39) |
W527R |
|
Het |
| Ighe |
A |
T |
12: 113,235,975 (GRCm39) |
I117N |
|
Het |
| Ighv1-50 |
T |
C |
12: 115,083,396 (GRCm39) |
E108G |
probably benign |
Het |
| Ivl |
G |
A |
3: 92,479,538 (GRCm39) |
P176S |
probably damaging |
Het |
| Lamb2 |
T |
A |
9: 108,361,283 (GRCm39) |
L605Q |
possibly damaging |
Het |
| Lgi3 |
G |
A |
14: 70,770,832 (GRCm39) |
R157H |
probably damaging |
Het |
| Lrp1b |
G |
T |
2: 41,266,006 (GRCm39) |
C1053* |
probably null |
Het |
| Mcpt9 |
A |
T |
14: 56,264,445 (GRCm39) |
S217T |
probably damaging |
Het |
| Mgat4c |
T |
G |
10: 102,224,357 (GRCm39) |
N190K |
probably damaging |
Het |
| Mknk1 |
T |
A |
4: 115,721,789 (GRCm39) |
V111D |
probably damaging |
Het |
| Mmp11 |
T |
C |
10: 75,764,280 (GRCm39) |
T62A |
probably benign |
Het |
| Mmp1b |
C |
A |
9: 7,385,014 (GRCm39) |
V212F |
probably damaging |
Het |
| Mmp7 |
A |
G |
9: 7,697,587 (GRCm39) |
|
probably null |
Het |
| Muc5b |
C |
T |
7: 141,417,704 (GRCm39) |
T3550M |
possibly damaging |
Het |
| Nbeal1 |
G |
C |
1: 60,276,310 (GRCm39) |
V684L |
probably benign |
Het |
| Nphp3 |
A |
T |
9: 103,882,036 (GRCm39) |
K169* |
probably null |
Het |
| Npy6r |
G |
T |
18: 44,408,788 (GRCm39) |
V70F |
probably benign |
Het |
| Nsun2 |
T |
A |
13: 69,774,672 (GRCm39) |
|
probably null |
Het |
| Oplah |
T |
A |
15: 76,186,860 (GRCm39) |
I652F |
probably benign |
Het |
| Pcdh18 |
T |
C |
3: 49,710,271 (GRCm39) |
N348S |
probably damaging |
Het |
| Pcdhb5 |
T |
A |
18: 37,454,409 (GRCm39) |
V263D |
probably damaging |
Het |
| Pcdhga1 |
C |
A |
18: 37,795,164 (GRCm39) |
T56N |
probably benign |
Het |
| Pdk4 |
A |
G |
6: 5,491,068 (GRCm39) |
|
probably null |
Het |
| Pfkp |
C |
A |
13: 6,652,817 (GRCm39) |
V434F |
probably benign |
Het |
| Phospho1 |
G |
A |
11: 95,721,732 (GRCm39) |
R134H |
probably damaging |
Het |
| Polg2 |
G |
T |
11: 106,663,572 (GRCm39) |
Q374K |
probably benign |
Het |
| Ptpra |
T |
C |
2: 130,379,571 (GRCm39) |
|
probably null |
Het |
| Rassf3 |
C |
T |
10: 121,252,052 (GRCm39) |
E120K |
probably benign |
Het |
| Reln |
A |
T |
5: 22,311,095 (GRCm39) |
S273T |
probably damaging |
Het |
| Scarb1 |
C |
T |
5: 125,361,089 (GRCm39) |
A133T |
probably benign |
Het |
| Scn3a |
T |
A |
2: 65,313,486 (GRCm39) |
K1142N |
probably damaging |
Het |
| Sema3c |
G |
A |
5: 17,899,701 (GRCm39) |
V398I |
probably benign |
Het |
| Serpine1 |
C |
A |
5: 137,099,918 (GRCm39) |
Q80H |
probably damaging |
Het |
| Sh3gl1 |
G |
A |
17: 56,324,646 (GRCm39) |
T334M |
probably damaging |
Het |
| Smg7 |
T |
C |
1: 152,737,576 (GRCm39) |
N122D |
probably benign |
Het |
| Speer4b |
T |
C |
5: 27,703,708 (GRCm39) |
I144V |
probably benign |
Het |
| Spire2 |
T |
A |
8: 124,095,989 (GRCm39) |
D671E |
probably benign |
Het |
| Sspo |
A |
T |
6: 48,478,029 (GRCm39) |
H5144L |
probably benign |
Het |
| Sstr2 |
A |
T |
11: 113,516,179 (GRCm39) |
Q366L |
probably damaging |
Het |
| Ssu72 |
T |
C |
4: 155,815,850 (GRCm39) |
F98S |
probably damaging |
Het |
| Syde2 |
C |
T |
3: 145,712,870 (GRCm39) |
Q1003* |
probably null |
Het |
| Tapbp |
G |
A |
17: 34,144,461 (GRCm39) |
A186T |
possibly damaging |
Het |
| Tcf12 |
T |
A |
9: 71,790,385 (GRCm39) |
|
probably null |
Het |
| Tnfrsf22 |
A |
T |
7: 143,194,556 (GRCm39) |
C124S |
probably damaging |
Het |
| Txlnb |
A |
T |
10: 17,703,546 (GRCm39) |
T235S |
possibly damaging |
Het |
| Uaca |
T |
C |
9: 60,777,695 (GRCm39) |
L694P |
probably damaging |
Het |
| Unc13a |
T |
A |
8: 72,083,197 (GRCm39) |
N1620Y |
probably damaging |
Het |
| Vmn2r10 |
C |
T |
5: 109,151,200 (GRCm39) |
C138Y |
probably damaging |
Het |
| Vmn2r111 |
T |
C |
17: 22,778,032 (GRCm39) |
N549S |
possibly damaging |
Het |
| Vmn2r28 |
T |
A |
7: 5,484,495 (GRCm39) |
E568D |
probably benign |
Het |
| Vmn2r57 |
A |
T |
7: 41,097,895 (GRCm39) |
H57Q |
possibly damaging |
Het |
| Vwa5b1 |
A |
G |
4: 138,308,923 (GRCm39) |
S756P |
probably benign |
Het |
| Washc5 |
C |
A |
15: 59,224,350 (GRCm39) |
E470* |
probably null |
Het |
| Xpot |
A |
T |
10: 121,442,678 (GRCm39) |
V508D |
probably damaging |
Het |
| Zfp616 |
A |
T |
11: 73,976,087 (GRCm39) |
K785N |
possibly damaging |
Het |
| Zfp653 |
T |
C |
9: 21,977,195 (GRCm39) |
N119D |
probably damaging |
Het |
| Zfp729b |
A |
G |
13: 67,741,495 (GRCm39) |
S257P |
probably damaging |
Het |
| Zfp82 |
T |
A |
7: 29,755,592 (GRCm39) |
T497S |
probably benign |
Het |
| Znrf4 |
T |
G |
17: 56,819,305 (GRCm39) |
M1L |
probably benign |
Het |
|
| Other mutations in Abca14 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00486:Abca14
|
APN |
7 |
119,846,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00800:Abca14
|
APN |
7 |
119,854,613 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00845:Abca14
|
APN |
7 |
119,823,174 (GRCm39) |
splice site |
probably benign |
|
|
IGL00897:Abca14
|
APN |
7 |
119,815,348 (GRCm39) |
splice site |
probably benign |
|
|
IGL01524:Abca14
|
APN |
7 |
119,852,644 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
IGL01747:Abca14
|
APN |
7 |
119,877,310 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02214:Abca14
|
APN |
7 |
119,893,398 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02215:Abca14
|
APN |
7 |
119,852,612 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02253:Abca14
|
APN |
7 |
119,807,182 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL02302:Abca14
|
APN |
7 |
119,917,968 (GRCm39) |
splice site |
probably benign |
|
|
IGL03391:Abca14
|
APN |
7 |
119,846,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F6893:Abca14
|
UTSW |
7 |
119,924,261 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0109:Abca14
|
UTSW |
7 |
119,917,985 (GRCm39) |
nonsense |
probably null |
|
|
R0109:Abca14
|
UTSW |
7 |
119,917,985 (GRCm39) |
nonsense |
probably null |
|
|
R0265:Abca14
|
UTSW |
7 |
119,822,850 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0326:Abca14
|
UTSW |
7 |
119,823,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0380:Abca14
|
UTSW |
7 |
119,877,703 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0418:Abca14
|
UTSW |
7 |
119,806,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0539:Abca14
|
UTSW |
7 |
119,807,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0574:Abca14
|
UTSW |
7 |
119,823,720 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0611:Abca14
|
UTSW |
7 |
119,851,479 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R0783:Abca14
|
UTSW |
7 |
119,893,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0785:Abca14
|
UTSW |
7 |
119,893,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0863:Abca14
|
UTSW |
7 |
119,815,453 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1034:Abca14
|
UTSW |
7 |
119,815,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1056:Abca14
|
UTSW |
7 |
119,924,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1072:Abca14
|
UTSW |
7 |
119,811,992 (GRCm39) |
missense |
probably benign |
|
|
R1244:Abca14
|
UTSW |
7 |
119,815,561 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1255:Abca14
|
UTSW |
7 |
119,807,016 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1271:Abca14
|
UTSW |
7 |
119,924,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1325:Abca14
|
UTSW |
7 |
119,846,545 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1457:Abca14
|
UTSW |
7 |
119,888,683 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1467:Abca14
|
UTSW |
7 |
119,815,405 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1467:Abca14
|
UTSW |
7 |
119,815,405 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1494:Abca14
|
UTSW |
7 |
119,815,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1551:Abca14
|
UTSW |
7 |
119,918,101 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1607:Abca14
|
UTSW |
7 |
119,850,514 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1739:Abca14
|
UTSW |
7 |
119,877,529 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1856:Abca14
|
UTSW |
7 |
119,877,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Abca14
|
UTSW |
7 |
119,847,190 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1892:Abca14
|
UTSW |
7 |
119,815,561 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1898:Abca14
|
UTSW |
7 |
119,850,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1958:Abca14
|
UTSW |
7 |
119,924,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2018:Abca14
|
UTSW |
7 |
119,815,408 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2039:Abca14
|
UTSW |
7 |
119,911,487 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2060:Abca14
|
UTSW |
7 |
119,826,741 (GRCm39) |
nonsense |
probably null |
|
|
R2202:Abca14
|
UTSW |
7 |
119,888,764 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2205:Abca14
|
UTSW |
7 |
119,846,503 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2360:Abca14
|
UTSW |
7 |
119,850,431 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2401:Abca14
|
UTSW |
7 |
119,882,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2426:Abca14
|
UTSW |
7 |
119,882,446 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3433:Abca14
|
UTSW |
7 |
119,893,455 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4598:Abca14
|
UTSW |
7 |
119,854,626 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4599:Abca14
|
UTSW |
7 |
119,854,626 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4700:Abca14
|
UTSW |
7 |
119,911,928 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4751:Abca14
|
UTSW |
7 |
119,911,400 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4826:Abca14
|
UTSW |
7 |
119,815,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4828:Abca14
|
UTSW |
7 |
119,815,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4837:Abca14
|
UTSW |
7 |
119,846,203 (GRCm39) |
missense |
probably benign |
|
|
R4881:Abca14
|
UTSW |
7 |
119,877,472 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R4895:Abca14
|
UTSW |
7 |
119,846,572 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4928:Abca14
|
UTSW |
7 |
119,923,803 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4990:Abca14
|
UTSW |
7 |
119,911,388 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Abca14
|
UTSW |
7 |
119,911,505 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5091:Abca14
|
UTSW |
7 |
119,851,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5158:Abca14
|
UTSW |
7 |
119,852,652 (GRCm39) |
missense |
probably benign |
|
|
R5209:Abca14
|
UTSW |
7 |
119,832,130 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5333:Abca14
|
UTSW |
7 |
119,888,769 (GRCm39) |
nonsense |
probably null |
|
|
R5424:Abca14
|
UTSW |
7 |
119,810,777 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5488:Abca14
|
UTSW |
7 |
119,851,473 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5489:Abca14
|
UTSW |
7 |
119,851,473 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5716:Abca14
|
UTSW |
7 |
119,846,217 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6450:Abca14
|
UTSW |
7 |
119,815,449 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6477:Abca14
|
UTSW |
7 |
119,924,325 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6652:Abca14
|
UTSW |
7 |
119,846,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6782:Abca14
|
UTSW |
7 |
119,847,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6874:Abca14
|
UTSW |
7 |
119,851,428 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6965:Abca14
|
UTSW |
7 |
119,882,452 (GRCm39) |
nonsense |
probably null |
|
|
R7142:Abca14
|
UTSW |
7 |
119,850,406 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7202:Abca14
|
UTSW |
7 |
119,917,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7220:Abca14
|
UTSW |
7 |
119,826,667 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
R7241:Abca14
|
UTSW |
7 |
119,846,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7291:Abca14
|
UTSW |
7 |
119,888,832 (GRCm39) |
nonsense |
probably null |
|
|
R7296:Abca14
|
UTSW |
7 |
119,877,534 (GRCm39) |
missense |
probably benign |
|
|
R7298:Abca14
|
UTSW |
7 |
119,807,106 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7315:Abca14
|
UTSW |
7 |
119,893,341 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7776:Abca14
|
UTSW |
7 |
119,832,214 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7820:Abca14
|
UTSW |
7 |
119,811,944 (GRCm39) |
missense |
probably benign |
0.42 |
|
R7873:Abca14
|
UTSW |
7 |
119,888,792 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8215:Abca14
|
UTSW |
7 |
119,893,425 (GRCm39) |
missense |
probably benign |
|
|
R8332:Abca14
|
UTSW |
7 |
119,815,436 (GRCm39) |
missense |
probably benign |
|
|
R8419:Abca14
|
UTSW |
7 |
119,815,489 (GRCm39) |
missense |
probably benign |
0.08 |
|
R8444:Abca14
|
UTSW |
7 |
119,918,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8818:Abca14
|
UTSW |
7 |
119,815,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8834:Abca14
|
UTSW |
7 |
119,877,372 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8845:Abca14
|
UTSW |
7 |
119,846,428 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8889:Abca14
|
UTSW |
7 |
119,815,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8892:Abca14
|
UTSW |
7 |
119,815,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8894:Abca14
|
UTSW |
7 |
119,847,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8903:Abca14
|
UTSW |
7 |
119,815,526 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8950:Abca14
|
UTSW |
7 |
119,823,595 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8950:Abca14
|
UTSW |
7 |
119,823,644 (GRCm39) |
nonsense |
probably null |
|
|
R9018:Abca14
|
UTSW |
7 |
119,918,532 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9018:Abca14
|
UTSW |
7 |
119,888,763 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9110:Abca14
|
UTSW |
7 |
119,831,615 (GRCm39) |
intron |
probably benign |
|
|
R9254:Abca14
|
UTSW |
7 |
119,807,202 (GRCm39) |
nonsense |
probably null |
|
|
R9376:Abca14
|
UTSW |
7 |
119,893,438 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9378:Abca14
|
UTSW |
7 |
119,807,191 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9379:Abca14
|
UTSW |
7 |
119,807,202 (GRCm39) |
nonsense |
probably null |
|
|
R9388:Abca14
|
UTSW |
7 |
119,882,261 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9445:Abca14
|
UTSW |
7 |
119,877,691 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9522:Abca14
|
UTSW |
7 |
119,847,368 (GRCm39) |
missense |
probably null |
0.98 |
|
R9577:Abca14
|
UTSW |
7 |
119,810,768 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9627:Abca14
|
UTSW |
7 |
119,854,530 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9639:Abca14
|
UTSW |
7 |
119,893,345 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Abca14
|
UTSW |
7 |
119,851,478 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9696:Abca14
|
UTSW |
7 |
119,888,734 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9709:Abca14
|
UTSW |
7 |
119,888,739 (GRCm39) |
nonsense |
probably null |
|
|
R9780:Abca14
|
UTSW |
7 |
119,911,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Abca14
|
UTSW |
7 |
119,815,358 (GRCm39) |
missense |
probably benign |
0.14 |
|
Z1176:Abca14
|
UTSW |
7 |
119,846,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Abca14
|
UTSW |
7 |
119,917,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACAATGTCGCTGGTCTGC -3'
(R):5'- AGCCTTCAACATGGTCTCAAG -3'
Sequencing Primer
(F):5'- CCAGCTGGGCTCTTCCTTCTG -3'
(R):5'- TGGGTCAAATTGGGGTCCCC -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation