Incidental Mutation 'R0605:Prrc2c'
| ID |
55620 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prrc2c
|
| Ensembl Gene |
ENSMUSG00000040225 |
| Gene Name |
proline-rich coiled-coil 2C |
| Synonyms |
9630039I18Rik, Bat2d, 1810043M20Rik, Bat2l2 |
| MMRRC Submission |
038794-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.410)
|
| Stock # |
R0605 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
162499354-162568125 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 162509995 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1017
(T1017A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138451
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028016]
[ENSMUST00000182149]
[ENSMUST00000182393]
[ENSMUST00000182593]
[ENSMUST00000182660]
[ENSMUST00000183223]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000028016
AA Change: T2299A
PolyPhen 2
Score 0.528 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000028016
Gene: ENSMUSG00000040225
AA Change: T2299A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
164 |
7.7e-56 |
PFAM |
|
internal_repeat_2
|
167 |
349 |
4.39e-5 |
PROSPERO |
|
internal_repeat_1
|
336 |
391 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
407 |
414 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
447 |
591 |
2e-5 |
SMART |
|
low complexity region
|
649 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
745 |
N/A |
INTRINSIC |
|
coiled coil region
|
996 |
1026 |
N/A |
INTRINSIC |
|
low complexity region
|
1157 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1212 |
1222 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1240 |
1295 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
1308 |
1335 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1409 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1765 |
1803 |
N/A |
INTRINSIC |
|
low complexity region
|
1815 |
1832 |
N/A |
INTRINSIC |
|
low complexity region
|
1844 |
1909 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1962 |
2148 |
4.39e-5 |
PROSPERO |
|
low complexity region
|
2163 |
2177 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2272 |
2286 |
N/A |
INTRINSIC |
|
low complexity region
|
2321 |
2338 |
N/A |
INTRINSIC |
|
low complexity region
|
2427 |
2438 |
N/A |
INTRINSIC |
|
low complexity region
|
2553 |
2576 |
N/A |
INTRINSIC |
|
low complexity region
|
2811 |
2828 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000182149
AA Change: T2301A
PolyPhen 2
Score 0.891 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000138548
Gene: ENSMUSG00000040225
AA Change: T2301A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
167 |
5.6e-73 |
PFAM |
|
internal_repeat_1
|
336 |
391 |
1.49e-5 |
PROSPERO |
|
low complexity region
|
407 |
414 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
447 |
591 |
2e-5 |
SMART |
|
low complexity region
|
649 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
745 |
N/A |
INTRINSIC |
|
internal_repeat_3
|
754 |
925 |
9.16e-5 |
PROSPERO |
|
coiled coil region
|
996 |
1026 |
N/A |
INTRINSIC |
|
low complexity region
|
1157 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1212 |
1222 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1240 |
1295 |
1.49e-5 |
PROSPERO |
|
low complexity region
|
1308 |
1335 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1409 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1765 |
1803 |
N/A |
INTRINSIC |
|
low complexity region
|
1815 |
1832 |
N/A |
INTRINSIC |
|
low complexity region
|
1844 |
1909 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1962 |
2148 |
3.08e-5 |
PROSPERO |
|
internal_repeat_3
|
1983 |
2153 |
9.16e-5 |
PROSPERO |
|
low complexity region
|
2163 |
2177 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2272 |
2286 |
N/A |
INTRINSIC |
|
low complexity region
|
2321 |
2338 |
N/A |
INTRINSIC |
|
low complexity region
|
2427 |
2438 |
N/A |
INTRINSIC |
|
low complexity region
|
2553 |
2576 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000182393
AA Change: T1017A
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000138451
Gene: ENSMUSG00000040225
AA Change: T1017A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
24 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
104 |
125 |
N/A |
INTRINSIC |
|
low complexity region
|
431 |
462 |
N/A |
INTRINSIC |
|
low complexity region
|
481 |
519 |
N/A |
INTRINSIC |
|
low complexity region
|
531 |
548 |
N/A |
INTRINSIC |
|
low complexity region
|
560 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
879 |
893 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
968 |
N/A |
INTRINSIC |
|
low complexity region
|
988 |
1002 |
N/A |
INTRINSIC |
|
low complexity region
|
1037 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1143 |
1154 |
N/A |
INTRINSIC |
|
low complexity region
|
1274 |
1297 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000182535
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000182593
AA Change: T2299A
PolyPhen 2
Score 0.891 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000138674
Gene: ENSMUSG00000040225
AA Change: T2299A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
165 |
4.1e-70 |
PFAM |
|
internal_repeat_1
|
334 |
389 |
9.57e-6 |
PROSPERO |
|
low complexity region
|
405 |
412 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
445 |
589 |
3e-5 |
SMART |
|
low complexity region
|
647 |
667 |
N/A |
INTRINSIC |
|
low complexity region
|
731 |
743 |
N/A |
INTRINSIC |
|
internal_repeat_3
|
752 |
923 |
6.11e-5 |
PROSPERO |
|
coiled coil region
|
994 |
1024 |
N/A |
INTRINSIC |
|
low complexity region
|
1155 |
1184 |
N/A |
INTRINSIC |
|
low complexity region
|
1210 |
1220 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1238 |
1293 |
9.57e-6 |
PROSPERO |
|
low complexity region
|
1306 |
1333 |
N/A |
INTRINSIC |
|
low complexity region
|
1386 |
1407 |
N/A |
INTRINSIC |
|
low complexity region
|
1713 |
1744 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1801 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1830 |
N/A |
INTRINSIC |
|
low complexity region
|
1842 |
1907 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1960 |
2146 |
2.01e-5 |
PROSPERO |
|
internal_repeat_3
|
1981 |
2151 |
6.11e-5 |
PROSPERO |
|
low complexity region
|
2161 |
2175 |
N/A |
INTRINSIC |
|
low complexity region
|
2228 |
2250 |
N/A |
INTRINSIC |
|
low complexity region
|
2270 |
2284 |
N/A |
INTRINSIC |
|
low complexity region
|
2319 |
2336 |
N/A |
INTRINSIC |
|
low complexity region
|
2425 |
2436 |
N/A |
INTRINSIC |
|
low complexity region
|
2551 |
2574 |
N/A |
INTRINSIC |
|
low complexity region
|
2671 |
2682 |
N/A |
INTRINSIC |
|
low complexity region
|
2730 |
2747 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000182660
AA Change: T2301A
PolyPhen 2
Score 0.767 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000138433
Gene: ENSMUSG00000040225
AA Change: T2301A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
167 |
7e-73 |
PFAM |
|
internal_repeat_1
|
336 |
391 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
407 |
414 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
447 |
591 |
2e-5 |
SMART |
|
low complexity region
|
649 |
669 |
N/A |
INTRINSIC |
|
low complexity region
|
733 |
745 |
N/A |
INTRINSIC |
|
coiled coil region
|
996 |
1026 |
N/A |
INTRINSIC |
|
low complexity region
|
1157 |
1186 |
N/A |
INTRINSIC |
|
low complexity region
|
1212 |
1222 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1240 |
1295 |
2.14e-5 |
PROSPERO |
|
low complexity region
|
1308 |
1335 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1409 |
N/A |
INTRINSIC |
|
low complexity region
|
1715 |
1746 |
N/A |
INTRINSIC |
|
low complexity region
|
1765 |
1803 |
N/A |
INTRINSIC |
|
low complexity region
|
1815 |
1832 |
N/A |
INTRINSIC |
|
low complexity region
|
1844 |
1909 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1962 |
2148 |
4.39e-5 |
PROSPERO |
|
low complexity region
|
2163 |
2177 |
N/A |
INTRINSIC |
|
low complexity region
|
2230 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2272 |
2286 |
N/A |
INTRINSIC |
|
low complexity region
|
2321 |
2338 |
N/A |
INTRINSIC |
|
low complexity region
|
2427 |
2438 |
N/A |
INTRINSIC |
|
low complexity region
|
2553 |
2576 |
N/A |
INTRINSIC |
|
low complexity region
|
2811 |
2828 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000183223
AA Change: T810A
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000138698
Gene: ENSMUSG00000040225
AA Change: T810A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
289 |
320 |
N/A |
INTRINSIC |
|
low complexity region
|
339 |
377 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
406 |
N/A |
INTRINSIC |
|
low complexity region
|
418 |
483 |
N/A |
INTRINSIC |
|
low complexity region
|
739 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
781 |
795 |
N/A |
INTRINSIC |
|
low complexity region
|
830 |
847 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
947 |
N/A |
INTRINSIC |
|
low complexity region
|
1062 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1182 |
1193 |
N/A |
INTRINSIC |
|
low complexity region
|
1241 |
1258 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0678 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.9%
- 10x: 97.6%
- 20x: 95.4%
|
| Validation Efficiency |
100% (85/85) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933406P04Rik |
G |
A |
10: 20,186,973 (GRCm39) |
|
probably benign |
Het |
| Adam28 |
A |
T |
14: 68,844,049 (GRCm39) |
|
probably benign |
Het |
| Adamts3 |
A |
G |
5: 90,009,334 (GRCm39) |
W110R |
possibly damaging |
Het |
| Add1 |
T |
C |
5: 34,771,568 (GRCm39) |
V342A |
possibly damaging |
Het |
| Aff3 |
A |
G |
1: 38,249,068 (GRCm39) |
S680P |
probably damaging |
Het |
| Ak9 |
T |
C |
10: 41,221,135 (GRCm39) |
Y322H |
probably damaging |
Het |
| Als2 |
A |
G |
1: 59,207,573 (GRCm39) |
L1528S |
probably benign |
Het |
| Ass1 |
A |
T |
2: 31,404,831 (GRCm39) |
N371Y |
probably damaging |
Het |
| Atp6v1a |
A |
C |
16: 43,931,859 (GRCm39) |
|
probably null |
Het |
| Bpi |
T |
C |
2: 158,103,314 (GRCm39) |
L103P |
probably damaging |
Het |
| Cd80 |
G |
A |
16: 38,303,056 (GRCm39) |
V168I |
probably benign |
Het |
| Cfh |
T |
C |
1: 140,030,096 (GRCm39) |
S926G |
probably damaging |
Het |
| Chrd |
A |
T |
16: 20,554,189 (GRCm39) |
T304S |
probably damaging |
Het |
| Chsy3 |
A |
G |
18: 59,542,125 (GRCm39) |
Y421C |
probably damaging |
Het |
| Cmbl |
T |
G |
15: 31,585,455 (GRCm39) |
V101G |
probably damaging |
Het |
| Colgalt2 |
T |
A |
1: 152,371,543 (GRCm39) |
|
probably benign |
Het |
| Coq4 |
C |
T |
2: 29,680,010 (GRCm39) |
Q101* |
probably null |
Het |
| Cr2 |
T |
C |
1: 194,845,904 (GRCm39) |
|
probably benign |
Het |
| Cry1 |
T |
C |
10: 85,020,223 (GRCm39) |
D38G |
probably damaging |
Het |
| Dmxl2 |
T |
C |
9: 54,327,229 (GRCm39) |
D758G |
probably benign |
Het |
| Epsti1 |
C |
T |
14: 78,164,677 (GRCm39) |
|
probably benign |
Het |
| Fam24b |
T |
C |
7: 130,928,915 (GRCm39) |
|
probably benign |
Het |
| Fem1c |
G |
A |
18: 46,638,227 (GRCm39) |
R592C |
probably benign |
Het |
| Foxred1 |
T |
C |
9: 35,116,178 (GRCm39) |
Y490C |
possibly damaging |
Het |
| Gm9875 |
A |
G |
2: 13,562,699 (GRCm39) |
K9R |
unknown |
Het |
| Grid2ip |
T |
C |
5: 143,365,117 (GRCm39) |
S322P |
probably damaging |
Het |
| Gucy1b2 |
A |
G |
14: 62,640,608 (GRCm39) |
|
probably benign |
Het |
| Hmcn1 |
A |
T |
1: 150,533,127 (GRCm39) |
|
probably null |
Het |
| Hpdl |
C |
T |
4: 116,677,984 (GRCm39) |
S159N |
possibly damaging |
Het |
| Hsd17b12 |
A |
T |
2: 93,863,987 (GRCm39) |
M285K |
probably benign |
Het |
| Icam5 |
T |
C |
9: 20,943,493 (GRCm39) |
I23T |
probably benign |
Het |
| Kat5 |
A |
G |
19: 5,658,364 (GRCm39) |
|
probably benign |
Het |
| Lama3 |
A |
G |
18: 12,640,006 (GRCm39) |
N67S |
probably benign |
Het |
| Lamb2 |
T |
C |
9: 108,363,304 (GRCm39) |
|
probably benign |
Het |
| Lgals3bp |
A |
G |
11: 118,284,220 (GRCm39) |
F453S |
probably damaging |
Het |
| Lypd4 |
A |
G |
7: 24,564,800 (GRCm39) |
Y113H |
probably damaging |
Het |
| Mdm1 |
C |
T |
10: 117,982,506 (GRCm39) |
T47M |
probably damaging |
Het |
| Mei1 |
C |
A |
15: 81,954,351 (GRCm39) |
T52K |
probably benign |
Het |
| Meiob |
G |
A |
17: 25,037,236 (GRCm39) |
|
probably benign |
Het |
| Ndufaf6 |
A |
G |
4: 11,051,224 (GRCm39) |
V292A |
probably damaging |
Het |
| Neb |
T |
A |
2: 52,154,038 (GRCm39) |
M2358L |
possibly damaging |
Het |
| Nlrp1b |
A |
G |
11: 71,047,005 (GRCm39) |
S1119P |
possibly damaging |
Het |
| Nsmaf |
A |
G |
4: 6,418,470 (GRCm39) |
|
probably null |
Het |
| Ogfod1 |
T |
C |
8: 94,773,895 (GRCm39) |
|
probably benign |
Het |
| Or5ae2 |
T |
C |
7: 84,506,345 (GRCm39) |
I256T |
probably damaging |
Het |
| Or8h7 |
T |
C |
2: 86,720,763 (GRCm39) |
Y252C |
possibly damaging |
Het |
| Or9s14 |
G |
T |
1: 92,535,618 (GRCm39) |
V20L |
probably benign |
Het |
| Osbpl1a |
T |
A |
18: 13,015,336 (GRCm39) |
|
probably null |
Het |
| Otud7b |
T |
A |
3: 96,052,270 (GRCm39) |
|
probably benign |
Het |
| P3h3 |
T |
A |
6: 124,832,998 (GRCm39) |
H185L |
probably damaging |
Het |
| P4htm |
G |
A |
9: 108,460,923 (GRCm39) |
A183V |
probably null |
Het |
| Peak1 |
C |
T |
9: 56,134,382 (GRCm39) |
|
probably benign |
Het |
| Phf20l1 |
A |
G |
15: 66,466,971 (GRCm39) |
K88R |
probably damaging |
Het |
| Phlpp2 |
A |
G |
8: 110,659,843 (GRCm39) |
N721S |
probably benign |
Het |
| Plagl2 |
T |
C |
2: 153,077,864 (GRCm39) |
K39R |
probably benign |
Het |
| Plppr1 |
A |
T |
4: 49,323,466 (GRCm39) |
N252I |
probably damaging |
Het |
| Pom121l2 |
C |
T |
13: 22,166,206 (GRCm39) |
A159V |
probably damaging |
Het |
| Prom2 |
C |
A |
2: 127,381,915 (GRCm39) |
|
probably null |
Het |
| Rimbp3 |
G |
T |
16: 17,029,563 (GRCm39) |
A996S |
probably damaging |
Het |
| Rnf213 |
A |
G |
11: 119,322,543 (GRCm39) |
T1387A |
probably benign |
Het |
| Scaper |
A |
T |
9: 55,722,802 (GRCm39) |
|
probably benign |
Het |
| Scara5 |
A |
G |
14: 65,997,097 (GRCm39) |
E403G |
possibly damaging |
Het |
| Scrib |
T |
C |
15: 75,939,402 (GRCm39) |
I94V |
possibly damaging |
Het |
| Shank3 |
T |
C |
15: 89,408,350 (GRCm39) |
F67L |
possibly damaging |
Het |
| Shprh |
T |
C |
10: 11,082,856 (GRCm39) |
F1562L |
probably damaging |
Het |
| Src |
C |
T |
2: 157,311,841 (GRCm39) |
T529M |
probably damaging |
Het |
| Sycp2l |
T |
A |
13: 41,296,942 (GRCm39) |
M341K |
probably benign |
Het |
| Syde1 |
T |
C |
10: 78,424,929 (GRCm39) |
|
probably benign |
Het |
| Tars3 |
A |
T |
7: 65,327,819 (GRCm39) |
R509S |
probably damaging |
Het |
| Tle6 |
T |
A |
10: 81,430,180 (GRCm39) |
H324L |
probably damaging |
Het |
| Tnfaip8 |
ACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC |
ACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC |
18: 50,179,912 (GRCm39) |
|
probably benign |
Het |
| Tnfrsf14 |
T |
A |
4: 155,009,837 (GRCm39) |
K115* |
probably null |
Het |
| Trappc10 |
T |
C |
10: 78,037,331 (GRCm39) |
N824S |
possibly damaging |
Het |
| Tsc1 |
C |
T |
2: 28,561,790 (GRCm39) |
S309F |
probably damaging |
Het |
| Ttc21a |
A |
G |
9: 119,790,908 (GRCm39) |
I885V |
possibly damaging |
Het |
| Ttn |
C |
T |
2: 76,570,797 (GRCm39) |
A26699T |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,778,715 (GRCm39) |
Y1262C |
unknown |
Het |
| Usp49 |
T |
C |
17: 47,985,851 (GRCm39) |
|
probably null |
Het |
| Vmn1r226 |
A |
T |
17: 20,908,133 (GRCm39) |
T122S |
probably benign |
Het |
| Vps8 |
A |
T |
16: 21,378,087 (GRCm39) |
T1033S |
probably benign |
Het |
| Vwf |
C |
A |
6: 125,662,800 (GRCm39) |
T2728K |
probably benign |
Het |
| Wdr5b |
T |
C |
16: 35,862,366 (GRCm39) |
S162P |
probably benign |
Het |
| Xrn1 |
C |
T |
9: 95,908,930 (GRCm39) |
Q1235* |
probably null |
Het |
| Zfp1005 |
A |
G |
2: 150,110,523 (GRCm39) |
I404M |
unknown |
Het |
|
| Other mutations in Prrc2c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00425:Prrc2c
|
APN |
1 |
162,548,182 (GRCm39) |
splice site |
probably null |
|
|
IGL00577:Prrc2c
|
APN |
1 |
162,525,685 (GRCm39) |
missense |
unknown |
|
|
IGL00580:Prrc2c
|
APN |
1 |
162,525,685 (GRCm39) |
missense |
unknown |
|
|
IGL01295:Prrc2c
|
APN |
1 |
162,510,061 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01554:Prrc2c
|
APN |
1 |
162,538,355 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01684:Prrc2c
|
APN |
1 |
162,534,031 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01745:Prrc2c
|
APN |
1 |
162,552,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01770:Prrc2c
|
APN |
1 |
162,532,068 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL01905:Prrc2c
|
APN |
1 |
162,532,898 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02304:Prrc2c
|
APN |
1 |
162,511,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02389:Prrc2c
|
APN |
1 |
162,520,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02540:Prrc2c
|
APN |
1 |
162,550,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02681:Prrc2c
|
APN |
1 |
162,533,181 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02686:Prrc2c
|
APN |
1 |
162,535,516 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02795:Prrc2c
|
APN |
1 |
162,541,868 (GRCm39) |
missense |
probably benign |
|
|
IGL02894:Prrc2c
|
APN |
1 |
162,505,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02957:Prrc2c
|
APN |
1 |
162,534,104 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02981:Prrc2c
|
APN |
1 |
162,532,748 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03070:Prrc2c
|
APN |
1 |
162,504,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03096:Prrc2c
|
APN |
1 |
162,529,928 (GRCm39) |
missense |
unknown |
|
|
R0058:Prrc2c
|
UTSW |
1 |
162,526,453 (GRCm39) |
missense |
unknown |
|
|
R0058:Prrc2c
|
UTSW |
1 |
162,526,453 (GRCm39) |
missense |
unknown |
|
|
R0135:Prrc2c
|
UTSW |
1 |
162,543,052 (GRCm39) |
splice site |
probably benign |
|
|
R0279:Prrc2c
|
UTSW |
1 |
162,543,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0363:Prrc2c
|
UTSW |
1 |
162,525,380 (GRCm39) |
missense |
unknown |
|
|
R0436:Prrc2c
|
UTSW |
1 |
162,532,883 (GRCm39) |
unclassified |
probably benign |
|
|
R0696:Prrc2c
|
UTSW |
1 |
162,536,421 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0981:Prrc2c
|
UTSW |
1 |
162,533,550 (GRCm39) |
unclassified |
probably benign |
|
|
R1693:Prrc2c
|
UTSW |
1 |
162,546,282 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1714:Prrc2c
|
UTSW |
1 |
162,504,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Prrc2c
|
UTSW |
1 |
162,532,551 (GRCm39) |
unclassified |
probably benign |
|
|
R1794:Prrc2c
|
UTSW |
1 |
162,533,528 (GRCm39) |
unclassified |
probably benign |
|
|
R1998:Prrc2c
|
UTSW |
1 |
162,532,487 (GRCm39) |
unclassified |
probably benign |
|
|
R2040:Prrc2c
|
UTSW |
1 |
162,525,126 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2168:Prrc2c
|
UTSW |
1 |
162,537,903 (GRCm39) |
unclassified |
probably benign |
|
|
R2246:Prrc2c
|
UTSW |
1 |
162,535,360 (GRCm39) |
unclassified |
probably benign |
|
|
R2830:Prrc2c
|
UTSW |
1 |
162,536,485 (GRCm39) |
unclassified |
probably benign |
|
|
R2926:Prrc2c
|
UTSW |
1 |
162,533,696 (GRCm39) |
unclassified |
probably benign |
|
|
R3703:Prrc2c
|
UTSW |
1 |
162,538,260 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3745:Prrc2c
|
UTSW |
1 |
162,525,754 (GRCm39) |
missense |
unknown |
|
|
R3760:Prrc2c
|
UTSW |
1 |
162,520,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3784:Prrc2c
|
UTSW |
1 |
162,537,238 (GRCm39) |
unclassified |
probably benign |
|
|
R3959:Prrc2c
|
UTSW |
1 |
162,536,461 (GRCm39) |
unclassified |
probably benign |
|
|
R4255:Prrc2c
|
UTSW |
1 |
162,533,895 (GRCm39) |
unclassified |
probably benign |
|
|
R4276:Prrc2c
|
UTSW |
1 |
162,501,160 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4421:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R4593:Prrc2c
|
UTSW |
1 |
162,525,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4651:Prrc2c
|
UTSW |
1 |
162,550,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4652:Prrc2c
|
UTSW |
1 |
162,550,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4660:Prrc2c
|
UTSW |
1 |
162,508,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4677:Prrc2c
|
UTSW |
1 |
162,532,748 (GRCm39) |
unclassified |
probably benign |
|
|
R4688:Prrc2c
|
UTSW |
1 |
162,525,256 (GRCm39) |
missense |
unknown |
|
|
R4753:Prrc2c
|
UTSW |
1 |
162,518,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4790:Prrc2c
|
UTSW |
1 |
162,538,050 (GRCm39) |
missense |
unknown |
|
|
R4981:Prrc2c
|
UTSW |
1 |
162,520,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4995:Prrc2c
|
UTSW |
1 |
162,532,879 (GRCm39) |
unclassified |
probably benign |
|
|
R5119:Prrc2c
|
UTSW |
1 |
162,533,009 (GRCm39) |
unclassified |
probably benign |
|
|
R5127:Prrc2c
|
UTSW |
1 |
162,525,415 (GRCm39) |
missense |
unknown |
|
|
R5291:Prrc2c
|
UTSW |
1 |
162,533,151 (GRCm39) |
unclassified |
probably benign |
|
|
R5474:Prrc2c
|
UTSW |
1 |
162,537,213 (GRCm39) |
unclassified |
probably benign |
|
|
R5543:Prrc2c
|
UTSW |
1 |
162,501,080 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5579:Prrc2c
|
UTSW |
1 |
162,508,327 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5594:Prrc2c
|
UTSW |
1 |
162,526,600 (GRCm39) |
missense |
unknown |
|
|
R5620:Prrc2c
|
UTSW |
1 |
162,501,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5994:Prrc2c
|
UTSW |
1 |
162,501,725 (GRCm39) |
splice site |
probably null |
|
|
R6142:Prrc2c
|
UTSW |
1 |
162,537,956 (GRCm39) |
missense |
unknown |
|
|
R6199:Prrc2c
|
UTSW |
1 |
162,510,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6277:Prrc2c
|
UTSW |
1 |
162,541,883 (GRCm39) |
missense |
probably benign |
|
|
R6504:Prrc2c
|
UTSW |
1 |
162,525,364 (GRCm39) |
missense |
unknown |
|
|
R6671:Prrc2c
|
UTSW |
1 |
162,525,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6785:Prrc2c
|
UTSW |
1 |
162,536,670 (GRCm39) |
unclassified |
probably benign |
|
|
R6799:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6801:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6850:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6851:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6856:Prrc2c
|
UTSW |
1 |
162,509,940 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6869:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6882:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6884:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R6897:Prrc2c
|
UTSW |
1 |
162,533,075 (GRCm39) |
unclassified |
probably benign |
|
|
R6934:Prrc2c
|
UTSW |
1 |
162,548,074 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6976:Prrc2c
|
UTSW |
1 |
162,520,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7132:Prrc2c
|
UTSW |
1 |
162,508,850 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7165:Prrc2c
|
UTSW |
1 |
162,501,086 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7282:Prrc2c
|
UTSW |
1 |
162,507,543 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R7467:Prrc2c
|
UTSW |
1 |
162,504,932 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7915:Prrc2c
|
UTSW |
1 |
162,519,977 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8068:Prrc2c
|
UTSW |
1 |
162,536,630 (GRCm39) |
unclassified |
probably benign |
|
|
R8529:Prrc2c
|
UTSW |
1 |
162,536,663 (GRCm39) |
unclassified |
probably benign |
|
|
R8734:Prrc2c
|
UTSW |
1 |
162,507,081 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8735:Prrc2c
|
UTSW |
1 |
162,537,127 (GRCm39) |
missense |
unknown |
|
|
R8813:Prrc2c
|
UTSW |
1 |
162,532,812 (GRCm39) |
missense |
unknown |
|
|
R8946:Prrc2c
|
UTSW |
1 |
162,536,478 (GRCm39) |
unclassified |
probably benign |
|
|
R8975:Prrc2c
|
UTSW |
1 |
162,533,630 (GRCm39) |
missense |
unknown |
|
|
R9035:Prrc2c
|
UTSW |
1 |
162,503,295 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9185:Prrc2c
|
UTSW |
1 |
162,532,212 (GRCm39) |
missense |
unknown |
|
|
R9261:Prrc2c
|
UTSW |
1 |
162,505,622 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R9287:Prrc2c
|
UTSW |
1 |
162,541,843 (GRCm39) |
missense |
probably benign |
0.34 |
|
R9289:Prrc2c
|
UTSW |
1 |
162,507,130 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9466:Prrc2c
|
UTSW |
1 |
162,503,258 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9523:Prrc2c
|
UTSW |
1 |
162,525,298 (GRCm39) |
missense |
unknown |
|
|
R9542:Prrc2c
|
UTSW |
1 |
162,508,359 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9629:Prrc2c
|
UTSW |
1 |
162,519,959 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9744:Prrc2c
|
UTSW |
1 |
162,505,733 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R9748:Prrc2c
|
UTSW |
1 |
162,535,435 (GRCm39) |
missense |
unknown |
|
|
X0020:Prrc2c
|
UTSW |
1 |
162,535,416 (GRCm39) |
unclassified |
probably benign |
|
|
X0039:Prrc2c
|
UTSW |
1 |
162,532,362 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTCATGGATGGAAGGGACTCAAACC -3'
(R):5'- CCAGTGGCCTATTTTCAGGTCAAGC -3'
Sequencing Primer
(F):5'- TCTAAGCAGCAAGAGTCACG -3'
(R):5'- GTACCTCCTGAGTATGGAGACTAC -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation