Incidental Mutation 'R7196:Magi3'
| ID |
559905 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Magi3
|
| Ensembl Gene |
ENSMUSG00000052539 |
| Gene Name |
membrane associated guanylate kinase, WW and PDZ domain containing 3 |
| Synonyms |
4732496O19Rik, 6530407C02Rik |
| MMRRC Submission |
045275-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.435)
|
| Stock # |
R7196 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
103920575-104127690 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 103956484 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Tryptophan
at position 661
(C661W)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067932
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064371]
[ENSMUST00000121198]
[ENSMUST00000122303]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064371
AA Change: C661W
PolyPhen 2
Score 0.007 (Sensitivity: 0.96; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000067932
Gene: ENSMUSG00000052539
AA Change: C661W
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000121198
AA Change: C661W
PolyPhen 2
Score 0.627 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000112934
Gene: ENSMUSG00000052539
AA Change: C661W
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000122303
AA Change: C661W
PolyPhen 2
Score 0.007 (Sensitivity: 0.96; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000113713
Gene: ENSMUSG00000052539
AA Change: C661W
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
14 |
N/A |
INTRINSIC |
|
PDZ
|
27 |
108 |
1.94e-1 |
SMART |
|
GuKc
|
114 |
281 |
8.56e-10 |
SMART |
|
WW
|
297 |
329 |
9.14e-12 |
SMART |
|
WW
|
343 |
375 |
2.47e-8 |
SMART |
|
PDZ
|
421 |
497 |
1.48e-17 |
SMART |
|
PDZ
|
589 |
659 |
3.07e-10 |
SMART |
|
low complexity region
|
664 |
674 |
N/A |
INTRINSIC |
|
low complexity region
|
683 |
698 |
N/A |
INTRINSIC |
|
PDZ
|
737 |
813 |
1.34e-15 |
SMART |
|
PDZ
|
861 |
939 |
7.65e-20 |
SMART |
|
PDZ
|
1030 |
1104 |
1.55e-20 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.5%
|
| Validation Efficiency |
99% (94/95) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017B05Rik |
AGCTTCCCTGCTT |
AGCTT |
9: 57,165,505 (GRCm39) |
|
probably null |
Het |
| 4921504E06Rik |
A |
C |
2: 19,498,806 (GRCm39) |
S396A |
probably benign |
Het |
| Actr6 |
C |
A |
10: 89,550,784 (GRCm39) |
V337F |
possibly damaging |
Het |
| Agtpbp1 |
T |
C |
13: 59,680,994 (GRCm39) |
T73A |
possibly damaging |
Het |
| AI182371 |
A |
T |
2: 34,976,441 (GRCm39) |
|
probably null |
Het |
| Apob |
A |
G |
12: 8,033,893 (GRCm39) |
E202G |
possibly damaging |
Het |
| Asb4 |
A |
T |
6: 5,423,356 (GRCm39) |
M168L |
probably benign |
Het |
| AU018091 |
T |
C |
7: 3,213,788 (GRCm39) |
Y152C |
probably damaging |
Het |
| Casp3 |
G |
A |
8: 47,088,498 (GRCm39) |
G132R |
possibly damaging |
Het |
| Cbfa2t3 |
C |
A |
8: 123,365,729 (GRCm39) |
A229S |
probably benign |
Het |
| Cdh23 |
A |
T |
10: 60,143,759 (GRCm39) |
Y2949N |
probably damaging |
Het |
| Ceacam3 |
T |
C |
7: 16,888,881 (GRCm39) |
Y217H |
|
Het |
| Cldn5 |
A |
T |
16: 18,595,630 (GRCm39) |
|
probably benign |
Het |
| Cltc |
T |
C |
11: 86,597,657 (GRCm39) |
D1093G |
probably damaging |
Het |
| Cnn3 |
G |
A |
3: 121,248,437 (GRCm39) |
|
probably null |
Het |
| Col4a2 |
A |
G |
8: 11,448,693 (GRCm39) |
Y71C |
probably damaging |
Het |
| Csf1 |
T |
C |
3: 107,661,214 (GRCm39) |
D77G |
possibly damaging |
Het |
| Cyp2j7 |
T |
A |
4: 96,103,651 (GRCm39) |
T295S |
probably benign |
Het |
| Dnah7a |
A |
T |
1: 53,724,000 (GRCm39) |
M133K |
probably benign |
Het |
| Dock5 |
G |
A |
14: 67,993,919 (GRCm39) |
P1852L |
probably damaging |
Het |
| Dpysl3 |
T |
A |
18: 43,462,910 (GRCm39) |
D489V |
probably damaging |
Het |
| Dsg4 |
T |
C |
18: 20,599,537 (GRCm39) |
Y718H |
probably damaging |
Het |
| Dync2h1 |
G |
A |
9: 7,147,715 (GRCm39) |
Q972* |
probably null |
Het |
| Epn1 |
G |
A |
7: 5,096,380 (GRCm39) |
D225N |
possibly damaging |
Het |
| Esp4 |
A |
G |
17: 40,913,256 (GRCm39) |
E41G |
probably benign |
Het |
| Fam171a2 |
T |
C |
11: 102,329,172 (GRCm39) |
D529G |
probably benign |
Het |
| Fbxl13 |
A |
T |
5: 21,691,301 (GRCm39) |
I694N |
probably damaging |
Het |
| Fshr |
C |
T |
17: 89,292,897 (GRCm39) |
A594T |
probably damaging |
Het |
| Galnt3 |
A |
G |
2: 65,921,268 (GRCm39) |
Y533H |
probably damaging |
Het |
| Gja5 |
C |
A |
3: 96,958,422 (GRCm39) |
R160S |
probably damaging |
Het |
| Gm12353 |
A |
T |
4: 19,608,938 (GRCm39) |
D7V |
unknown |
Het |
| Gm17669 |
T |
C |
18: 67,695,572 (GRCm39) |
F39S |
probably damaging |
Het |
| Gm7145 |
T |
A |
1: 117,913,791 (GRCm39) |
N224K |
possibly damaging |
Het |
| Gpd1 |
G |
T |
15: 99,619,936 (GRCm39) |
G245C |
probably benign |
Het |
| Gpr4 |
G |
A |
7: 18,957,089 (GRCm39) |
G337D |
probably benign |
Het |
| Hgd |
G |
A |
16: 37,409,078 (GRCm39) |
C14Y |
probably benign |
Het |
| Ibtk |
A |
T |
9: 85,625,709 (GRCm39) |
S14T |
probably damaging |
Het |
| Ifi205 |
G |
T |
1: 173,854,109 (GRCm39) |
N181K |
probably damaging |
Het |
| Inppl1 |
G |
A |
7: 101,477,993 (GRCm39) |
A673V |
probably benign |
Het |
| Itgb3 |
C |
A |
11: 104,524,438 (GRCm39) |
Y191* |
probably null |
Het |
| Jrkl |
G |
T |
9: 13,244,162 (GRCm39) |
P500T |
probably benign |
Het |
| Kcnq1 |
G |
A |
7: 142,912,478 (GRCm39) |
V515I |
possibly damaging |
Het |
| Kifc3 |
A |
G |
8: 95,833,239 (GRCm39) |
V453A |
probably benign |
Het |
| Krt10 |
C |
T |
11: 99,278,371 (GRCm39) |
E263K |
probably damaging |
Het |
| Lingo1 |
A |
T |
9: 56,527,903 (GRCm39) |
F235I |
probably damaging |
Het |
| Lmo7 |
T |
A |
14: 102,133,936 (GRCm39) |
D660E |
possibly damaging |
Het |
| Mmp1a |
C |
T |
9: 7,476,018 (GRCm39) |
Q428* |
probably null |
Het |
| Msrb1 |
A |
T |
17: 24,958,556 (GRCm39) |
T47S |
probably benign |
Het |
| Naip6 |
A |
T |
13: 100,436,666 (GRCm39) |
I619K |
probably benign |
Het |
| Ndfip2 |
T |
C |
14: 105,535,472 (GRCm39) |
S253P |
probably damaging |
Het |
| Nebl |
A |
T |
2: 17,457,329 (GRCm39) |
V77E |
probably damaging |
Het |
| Nit1 |
T |
C |
1: 171,172,003 (GRCm39) |
E65G |
probably benign |
Het |
| Ntn4 |
C |
T |
10: 93,569,576 (GRCm39) |
H430Y |
probably benign |
Het |
| Nxpe5 |
A |
T |
5: 138,237,586 (GRCm39) |
I49F |
probably benign |
Het |
| Or10a2 |
A |
G |
7: 106,673,935 (GRCm39) |
N300S |
probably benign |
Het |
| Or10c1 |
A |
G |
17: 37,522,084 (GRCm39) |
I220T |
probably damaging |
Het |
| Or14c46 |
A |
T |
7: 85,918,649 (GRCm39) |
M116K |
probably damaging |
Het |
| Or1e23 |
A |
G |
11: 73,407,957 (GRCm39) |
Y23H |
probably benign |
Het |
| Or1m1 |
A |
T |
9: 18,666,886 (GRCm39) |
L15* |
probably null |
Het |
| Or4k49 |
T |
G |
2: 111,495,042 (GRCm39) |
L157W |
probably damaging |
Het |
| Or52s6 |
A |
T |
7: 103,092,204 (GRCm39) |
M42K |
probably benign |
Het |
| Or7e178 |
A |
G |
9: 20,225,494 (GRCm39) |
Y241H |
probably benign |
Het |
| Oxct2a |
T |
A |
4: 123,217,165 (GRCm39) |
N72I |
probably damaging |
Het |
| Pappa |
G |
A |
4: 65,242,128 (GRCm39) |
|
probably null |
Het |
| Pcnx1 |
G |
A |
12: 82,042,312 (GRCm39) |
R34H |
possibly damaging |
Het |
| Plekha5 |
G |
T |
6: 140,489,648 (GRCm39) |
V236L |
possibly damaging |
Het |
| Prdm1 |
A |
G |
10: 44,332,988 (GRCm39) |
S44P |
probably benign |
Het |
| Prss46 |
T |
A |
9: 110,680,533 (GRCm39) |
L226Q |
probably benign |
Het |
| Prss47 |
C |
A |
13: 65,192,640 (GRCm39) |
W380C |
probably benign |
Het |
| Ptch2 |
T |
G |
4: 116,971,946 (GRCm39) |
V1156G |
probably benign |
Het |
| Rab3gap2 |
T |
C |
1: 185,013,864 (GRCm39) |
F1190S |
probably damaging |
Het |
| Raver2 |
T |
G |
4: 100,960,056 (GRCm39) |
Y179D |
probably damaging |
Het |
| Rgl2 |
C |
T |
17: 34,152,403 (GRCm39) |
R367W |
probably damaging |
Het |
| Ripor2 |
T |
G |
13: 24,888,808 (GRCm39) |
I629S |
possibly damaging |
Het |
| Robo4 |
T |
A |
9: 37,314,001 (GRCm39) |
M84K |
possibly damaging |
Het |
| Rps6ka5 |
A |
T |
12: 100,562,123 (GRCm39) |
S252T |
possibly damaging |
Het |
| Rtl1 |
C |
T |
12: 109,559,221 (GRCm39) |
V873M |
possibly damaging |
Het |
| Sla |
T |
A |
15: 66,703,420 (GRCm39) |
R4W |
probably benign |
Het |
| Smco1 |
A |
G |
16: 32,092,620 (GRCm39) |
D97G |
probably damaging |
Het |
| Srgap1 |
T |
C |
10: 121,676,753 (GRCm39) |
T414A |
probably benign |
Het |
| Syt14 |
A |
G |
1: 192,717,936 (GRCm39) |
I3T |
probably benign |
Het |
| Tnpo2 |
G |
A |
8: 85,773,766 (GRCm39) |
V303M |
possibly damaging |
Het |
| Tstd2 |
A |
C |
4: 46,119,955 (GRCm39) |
S332R |
probably damaging |
Het |
| Ttn |
C |
A |
2: 76,582,386 (GRCm39) |
A22836S |
possibly damaging |
Het |
| Ufl1 |
A |
G |
4: 25,250,669 (GRCm39) |
V728A |
probably benign |
Het |
| Usp33 |
A |
T |
3: 152,089,828 (GRCm39) |
K789N |
possibly damaging |
Het |
| Usp54 |
T |
A |
14: 20,638,438 (GRCm39) |
Q214L |
probably damaging |
Het |
| Vmn2r7 |
T |
G |
3: 64,623,198 (GRCm39) |
N374T |
probably benign |
Het |
| Zbtb7a |
T |
A |
10: 80,980,434 (GRCm39) |
N209K |
probably damaging |
Het |
| Zc3hav1 |
A |
G |
6: 38,306,207 (GRCm39) |
V615A |
probably benign |
Het |
| Zdhhc20 |
A |
G |
14: 58,111,348 (GRCm39) |
|
probably null |
Het |
| Zfp90 |
G |
T |
8: 107,151,780 (GRCm39) |
V498L |
probably damaging |
Het |
|
| Other mutations in Magi3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00429:Magi3
|
APN |
3 |
103,922,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00933:Magi3
|
APN |
3 |
103,923,163 (GRCm39) |
missense |
probably benign |
|
|
IGL01151:Magi3
|
APN |
3 |
103,958,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01674:Magi3
|
APN |
3 |
104,013,037 (GRCm39) |
splice site |
probably benign |
|
|
IGL01790:Magi3
|
APN |
3 |
103,992,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01903:Magi3
|
APN |
3 |
103,958,526 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01939:Magi3
|
APN |
3 |
103,961,778 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02142:Magi3
|
APN |
3 |
103,923,219 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL02183:Magi3
|
APN |
3 |
103,992,663 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02887:Magi3
|
APN |
3 |
104,002,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03071:Magi3
|
APN |
3 |
103,923,202 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL03085:Magi3
|
APN |
3 |
103,922,655 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL03192:Magi3
|
APN |
3 |
103,950,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Magi3
|
APN |
3 |
104,013,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03227:Magi3
|
APN |
3 |
103,958,435 (GRCm39) |
missense |
probably benign |
|
|
IGL03388:Magi3
|
APN |
3 |
103,923,157 (GRCm39) |
missense |
probably benign |
0.30 |
|
PIT4280001:Magi3
|
UTSW |
3 |
103,961,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4504001:Magi3
|
UTSW |
3 |
103,922,842 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0092:Magi3
|
UTSW |
3 |
103,958,280 (GRCm39) |
nonsense |
probably null |
|
|
R0514:Magi3
|
UTSW |
3 |
103,922,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0569:Magi3
|
UTSW |
3 |
103,923,358 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0608:Magi3
|
UTSW |
3 |
103,924,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0920:Magi3
|
UTSW |
3 |
103,941,507 (GRCm39) |
splice site |
probably null |
|
|
R1173:Magi3
|
UTSW |
3 |
103,968,946 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1256:Magi3
|
UTSW |
3 |
103,935,126 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1391:Magi3
|
UTSW |
3 |
103,922,374 (GRCm39) |
nonsense |
probably null |
|
|
R1559:Magi3
|
UTSW |
3 |
103,954,169 (GRCm39) |
splice site |
probably benign |
|
|
R1568:Magi3
|
UTSW |
3 |
103,996,843 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1631:Magi3
|
UTSW |
3 |
103,958,493 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1747:Magi3
|
UTSW |
3 |
103,941,489 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1930:Magi3
|
UTSW |
3 |
103,996,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1964:Magi3
|
UTSW |
3 |
103,927,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2151:Magi3
|
UTSW |
3 |
103,992,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2151:Magi3
|
UTSW |
3 |
103,954,198 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2266:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2267:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2268:Magi3
|
UTSW |
3 |
103,928,382 (GRCm39) |
intron |
probably benign |
|
|
R2519:Magi3
|
UTSW |
3 |
103,923,081 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3104:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3105:Magi3
|
UTSW |
3 |
103,958,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3619:Magi3
|
UTSW |
3 |
103,961,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4158:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4160:Magi3
|
UTSW |
3 |
103,958,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4284:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4285:Magi3
|
UTSW |
3 |
103,923,184 (GRCm39) |
nonsense |
probably null |
|
|
R4397:Magi3
|
UTSW |
3 |
104,127,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4512:Magi3
|
UTSW |
3 |
103,996,871 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4676:Magi3
|
UTSW |
3 |
103,923,141 (GRCm39) |
missense |
probably benign |
|
|
R4758:Magi3
|
UTSW |
3 |
103,922,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4940:Magi3
|
UTSW |
3 |
103,958,708 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Magi3
|
UTSW |
3 |
104,013,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5160:Magi3
|
UTSW |
3 |
103,935,224 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5422:Magi3
|
UTSW |
3 |
103,958,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5509:Magi3
|
UTSW |
3 |
103,922,818 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5839:Magi3
|
UTSW |
3 |
104,127,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Magi3
|
UTSW |
3 |
103,961,854 (GRCm39) |
splice site |
probably null |
|
|
R6018:Magi3
|
UTSW |
3 |
104,013,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Magi3
|
UTSW |
3 |
103,958,181 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6235:Magi3
|
UTSW |
3 |
103,923,384 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6244:Magi3
|
UTSW |
3 |
103,923,013 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6258:Magi3
|
UTSW |
3 |
103,996,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6358:Magi3
|
UTSW |
3 |
103,958,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6534:Magi3
|
UTSW |
3 |
103,992,536 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6806:Magi3
|
UTSW |
3 |
103,954,285 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6816:Magi3
|
UTSW |
3 |
103,997,227 (GRCm39) |
splice site |
probably null |
|
|
R6897:Magi3
|
UTSW |
3 |
103,996,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7011:Magi3
|
UTSW |
3 |
104,013,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7039:Magi3
|
UTSW |
3 |
103,958,699 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7237:Magi3
|
UTSW |
3 |
103,935,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7285:Magi3
|
UTSW |
3 |
103,941,430 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7709:Magi3
|
UTSW |
3 |
103,941,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7724:Magi3
|
UTSW |
3 |
103,923,243 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7797:Magi3
|
UTSW |
3 |
103,958,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7950:Magi3
|
UTSW |
3 |
103,924,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8140:Magi3
|
UTSW |
3 |
103,941,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8204:Magi3
|
UTSW |
3 |
103,958,502 (GRCm39) |
missense |
probably benign |
|
|
R8229:Magi3
|
UTSW |
3 |
103,923,018 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8229:Magi3
|
UTSW |
3 |
103,923,017 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R8260:Magi3
|
UTSW |
3 |
103,922,625 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8348:Magi3
|
UTSW |
3 |
103,958,531 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8368:Magi3
|
UTSW |
3 |
104,002,379 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8543:Magi3
|
UTSW |
3 |
104,126,984 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8762:Magi3
|
UTSW |
3 |
103,958,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Magi3
|
UTSW |
3 |
103,992,662 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8847:Magi3
|
UTSW |
3 |
103,922,334 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8892:Magi3
|
UTSW |
3 |
103,958,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8939:Magi3
|
UTSW |
3 |
103,996,748 (GRCm39) |
intron |
probably benign |
|
|
R9090:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9187:Magi3
|
UTSW |
3 |
103,923,073 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9271:Magi3
|
UTSW |
3 |
103,923,264 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9433:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9439:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9557:Magi3
|
UTSW |
3 |
103,924,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9557:Magi3
|
UTSW |
3 |
103,922,473 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9697:Magi3
|
UTSW |
3 |
103,956,458 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9796:Magi3
|
UTSW |
3 |
103,928,291 (GRCm39) |
missense |
probably benign |
|
|
X0026:Magi3
|
UTSW |
3 |
103,927,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCACAGACTTCAAAGGGAG -3'
(R):5'- CTGTTTCTGTGATTTAAGGAACCTC -3'
Sequencing Primer
(F):5'- AAGGGAGTTTCCTATCAATACCTGGG -3'
(R):5'- GCATTTATGCCTCTGGAG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation