Mutagenetix > Incidental Mutation

Incidental Mutation 'R0591:Pbrm1'

56000

Institutional Source

Beutler Lab

Gene Symbol

Pbrm1

Ensembl Gene

ENSMUSG00000042323

Gene Name

polybromo 1

Synonyms

2310032M22Rik, BAF180, 2610016F04Rik, Pb1

MMRRC Submission

038781-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R0591 (G1)

Quality Score

221

Status

Validated

Chromosome

Chromosomal Location

30741095-30843549 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 30768387 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000123546 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022471] [ENSMUST00000022474] [ENSMUST00000052239] [ENSMUST00000090214] [ENSMUST00000112092] [ENSMUST00000112094] [ENSMUST00000112095] [ENSMUST00000112098] [ENSMUST00000135704] [ENSMUST00000146325] [ENSMUST00000136237] [ENSMUST00000156628] [ENSMUST00000123678]

AlphaFold

Q8BSQ9

Predicted Effect

probably benign
Transcript: ENSMUST00000022471

SMART Domains

Protein: ENSMUSP00000022471
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	516	627	6.07e-39	SMART
BROMO	651	765	3.01e-43	SMART
BROMO	775	881	2.53e-18	SMART
coiled coil region	907	934	N/A	INTRINSIC
BAH	956	1074	1.33e-45	SMART
low complexity region	1083	1097	N/A	INTRINSIC
BAH	1156	1272	3.02e-35	SMART
low complexity region	1318	1338	N/A	INTRINSIC
HMG	1378	1450	8.91e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000022474

SMART Domains

Protein: ENSMUSP00000022474
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	531	642	6.07e-39	SMART
BROMO	666	780	3.01e-43	SMART
BROMO	790	896	2.53e-18	SMART
coiled coil region	922	949	N/A	INTRINSIC
BAH	971	1089	1.33e-45	SMART
low complexity region	1098	1112	N/A	INTRINSIC
BAH	1171	1287	3.02e-35	SMART
low complexity region	1333	1353	N/A	INTRINSIC
HMG	1393	1465	8.91e-10	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000052239

SMART Domains

Protein: ENSMUSP00000060476
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	516	627	6.07e-39	SMART
BROMO	651	765	3.01e-43	SMART
BROMO	775	881	2.53e-18	SMART
coiled coil region	907	934	N/A	INTRINSIC
BAH	956	1049	8.64e-22	SMART
low complexity region	1058	1072	N/A	INTRINSIC
BAH	1131	1247	3.02e-35	SMART
low complexity region	1293	1310	N/A	INTRINSIC
HMG	1326	1396	2.87e-13	SMART
low complexity region	1405	1430	N/A	INTRINSIC
low complexity region	1449	1477	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000090214

SMART Domains

Protein: ENSMUSP00000087682
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	516	627	6.07e-39	SMART
BROMO	651	765	3.01e-43	SMART
BROMO	775	881	2.53e-18	SMART
coiled coil region	907	934	N/A	INTRINSIC
BAH	956	1074	1.33e-45	SMART
low complexity region	1083	1097	N/A	INTRINSIC
BAH	1156	1272	3.02e-35	SMART
low complexity region	1318	1338	N/A	INTRINSIC
HMG	1378	1448	1.62e-21	SMART
low complexity region	1464	1475	N/A	INTRINSIC
low complexity region	1485	1500	N/A	INTRINSIC
low complexity region	1512	1537	N/A	INTRINSIC
low complexity region	1556	1584	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000112092

SMART Domains

Protein: ENSMUSP00000107721
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	531	642	6.07e-39	SMART
BROMO	666	780	3.01e-43	SMART
BROMO	790	896	2.53e-18	SMART
coiled coil region	922	949	N/A	INTRINSIC
BAH	971	1089	1.33e-45	SMART
low complexity region	1098	1112	N/A	INTRINSIC
BAH	1171	1287	3.02e-35	SMART
low complexity region	1333	1353	N/A	INTRINSIC
HMG	1393	1463	1.62e-21	SMART
low complexity region	1479	1490	N/A	INTRINSIC
low complexity region	1519	1547	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000112094

SMART Domains

Protein: ENSMUSP00000107723
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	322	338	N/A	INTRINSIC
BROMO	347	457	1.57e-32	SMART
BROMO	484	595	6.07e-39	SMART
BROMO	619	733	3.01e-43	SMART
BROMO	743	849	2.53e-18	SMART
coiled coil region	875	902	N/A	INTRINSIC
BAH	924	1042	1.33e-45	SMART
low complexity region	1051	1065	N/A	INTRINSIC
BAH	1124	1240	3.02e-35	SMART
low complexity region	1286	1306	N/A	INTRINSIC
HMG	1346	1416	2.87e-13	SMART
low complexity region	1425	1450	N/A	INTRINSIC
low complexity region	1469	1497	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000112095

SMART Domains

Protein: ENSMUSP00000107724
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	516	627	6.07e-39	SMART
BROMO	651	765	3.01e-43	SMART
BROMO	775	881	2.53e-18	SMART
coiled coil region	907	934	N/A	INTRINSIC
BAH	956	1074	1.33e-45	SMART
low complexity region	1083	1097	N/A	INTRINSIC
BAH	1156	1272	3.02e-35	SMART
low complexity region	1318	1338	N/A	INTRINSIC
HMG	1378	1448	2.87e-13	SMART
low complexity region	1457	1482	N/A	INTRINSIC
low complexity region	1501	1529	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000112098

SMART Domains

Protein: ENSMUSP00000107727
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	531	642	6.07e-39	SMART
BROMO	666	780	3.01e-43	SMART
BROMO	790	896	2.53e-18	SMART
coiled coil region	922	949	N/A	INTRINSIC
BAH	971	1089	1.33e-45	SMART
low complexity region	1098	1112	N/A	INTRINSIC
BAH	1171	1287	3.02e-35	SMART
low complexity region	1333	1353	N/A	INTRINSIC
HMG	1393	1463	1.62e-21	SMART
low complexity region	1479	1490	N/A	INTRINSIC
low complexity region	1500	1515	N/A	INTRINSIC
low complexity region	1527	1552	N/A	INTRINSIC
low complexity region	1571	1599	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000135704

SMART Domains

Protein: ENSMUSP00000115505
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	1	97	3.24e-25	SMART
BROMO	119	233	5.84e-41	SMART
low complexity region	298	314	N/A	INTRINSIC
BROMO	323	433	1.57e-32	SMART
BROMO	475	586	6.07e-39	SMART
BROMO	610	724	3.01e-43	SMART
BROMO	734	840	2.53e-18	SMART
low complexity region	862	892	N/A	INTRINSIC
BAH	914	1032	1.33e-45	SMART
low complexity region	1041	1055	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000146325

SMART Domains

Protein: ENSMUSP00000122805
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	64	174	4.97e-35	SMART
BROMO	196	310	5.84e-41	SMART
low complexity region	343	359	N/A	INTRINSIC
BROMO	368	478	1.57e-32	SMART
BROMO	505	616	6.07e-39	SMART
BROMO	640	754	3.01e-43	SMART
BROMO	764	870	2.53e-18	SMART
coiled coil region	896	923	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000136237

SMART Domains

Protein: ENSMUSP00000119722
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	516	627	6.07e-39	SMART
BROMO	651	765	3.01e-43	SMART
BROMO	775	859	7.08e-3	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000156628

SMART Domains

Protein: ENSMUSP00000123546
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	516	627	6.07e-39	SMART
BROMO	651	765	3.01e-43	SMART
BROMO	775	881	2.53e-18	SMART
low complexity region	903	933	N/A	INTRINSIC
BAH	955	1073	1.33e-45	SMART
low complexity region	1082	1096	N/A	INTRINSIC
BAH	1155	1271	3.02e-35	SMART
low complexity region	1317	1337	N/A	INTRINSIC
HMG	1377	1447	2.87e-13	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000123678

SMART Domains

Protein: ENSMUSP00000120549
Gene: ENSMUSG00000042323

Domain	Start	End	E-Value	Type
BROMO	43	153	4.97e-35	SMART
BROMO	175	289	5.84e-41	SMART
low complexity region	354	370	N/A	INTRINSIC
BROMO	379	489	1.57e-32	SMART
BROMO	516	627	6.07e-39	SMART
BROMO	651	765	3.01e-43	SMART
BROMO	775	856	2.3e-2	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000226537

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.7%
3x: 99.2%
10x: 97.7%
20x: 95.3%

Validation Efficiency

100% (62/62)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes a subunit of ATP-dependent chromatin-remodeling complexes. The encoded protein has been identified as in integral component of complexes necessary for ligand-dependent transcriptional activation by nuclear hormone receptors. Mutations at this locus have been associated with primary clear cell renal cell carcinoma. [provided by RefSeq, Feb 2012]
PHENOTYPE: Homozygous null mice display embryonic lethality with hypoplastic cardiac ventricular chambers and malformation of the placenta. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 59 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110002E22Rik	G	T	3: 137,774,704 (GRCm39)	E1298*	probably null	Het
Aadacl2fm2	C	A	3: 59,659,550 (GRCm39)	Y334*	probably null	Het
Adam19	T	C	11: 46,012,238 (GRCm39)		probably benign	Het
Agt	A	T	8: 125,283,678 (GRCm39)	S480R	possibly damaging	Het
Anapc1	G	T	2: 128,461,252 (GRCm39)	D1769E	probably benign	Het
Aox4	T	C	1: 58,278,261 (GRCm39)		probably benign	Het
Apol9b	G	A	15: 77,619,830 (GRCm39)	V209I	possibly damaging	Het
Appl2	A	T	10: 83,460,509 (GRCm39)	I116K	possibly damaging	Het
BC051665	A	G	13: 60,932,422 (GRCm39)		probably benign	Het
Cactin	G	T	10: 81,159,837 (GRCm39)	E89*	probably null	Het
Carf	G	T	1: 60,165,073 (GRCm39)		probably benign	Het
Ccdc167	A	G	17: 29,924,235 (GRCm39)		probably benign	Het
Ceacam3	G	A	7: 16,885,808 (GRCm39)		probably null	Het
Clca4b	T	A	3: 144,621,353 (GRCm39)	K574*	probably null	Het
Crabp1	T	A	9: 54,672,887 (GRCm39)	I64N	probably damaging	Het
Dgkd	T	A	1: 87,842,826 (GRCm39)	I118N	probably damaging	Het
Dglucy	T	C	12: 100,825,777 (GRCm39)		probably benign	Het
Dock10	C	T	1: 80,518,936 (GRCm39)		probably benign	Het
Ednrb	A	T	14: 104,060,710 (GRCm39)		probably null	Het
Ercc6	T	C	14: 32,279,973 (GRCm39)		probably benign	Het
Golga3	A	C	5: 110,336,609 (GRCm39)	Q416P	probably damaging	Het
Gpr12	A	G	5: 146,520,445 (GRCm39)	V159A	probably benign	Het
Heatr5a	A	T	12: 51,956,884 (GRCm39)		probably benign	Het
Helz2	A	G	2: 180,873,909 (GRCm39)	I2195T	probably damaging	Het
Hikeshi	A	T	7: 89,569,295 (GRCm39)	N76K	possibly damaging	Het
Hsd11b1	T	C	1: 192,911,984 (GRCm39)		probably benign	Het
Iftap	A	T	2: 101,406,462 (GRCm39)	D155E	probably benign	Het
Inhba	A	T	13: 16,201,405 (GRCm39)	K322N	probably damaging	Het
Katnal1	A	T	5: 148,829,326 (GRCm39)	F291L	probably damaging	Het
Kcnj9	T	C	1: 172,150,665 (GRCm39)	E316G	probably damaging	Het
Lrsam1	A	G	2: 32,823,935 (GRCm39)		probably benign	Het
Mcf2l	T	G	8: 13,068,751 (GRCm39)	S1075A	probably benign	Het
Mios	T	C	6: 8,215,470 (GRCm39)	V222A	possibly damaging	Het
Mycbp2	A	T	14: 103,433,827 (GRCm39)		probably benign	Het
Nars1	A	T	18: 64,633,638 (GRCm39)	I544N	probably damaging	Het
Or5ak23	A	G	2: 85,245,034 (GRCm39)	L63P	possibly damaging	Het
Plcb4	A	G	2: 135,796,932 (GRCm39)		probably benign	Het
Pnliprp1	A	G	19: 58,723,138 (GRCm39)	D213G	probably damaging	Het
Psap	A	G	10: 60,136,634 (GRCm39)	N538D	possibly damaging	Het
Ptdss1	A	G	13: 67,120,714 (GRCm39)		probably benign	Het
Rap1b	G	A	10: 117,654,522 (GRCm39)		probably benign	Het
Rhcg	T	A	7: 79,244,520 (GRCm39)		probably benign	Het
Ryr1	G	A	7: 28,804,220 (GRCm39)	T550I	possibly damaging	Het
Samm50	G	A	15: 84,095,369 (GRCm39)	G452R	probably benign	Het
Scin	A	G	12: 40,130,929 (GRCm39)		probably null	Het
Sesn3	T	C	9: 14,219,854 (GRCm39)	L81S	probably damaging	Het
Skint6	A	C	4: 112,715,366 (GRCm39)		probably benign	Het
Slc30a4	A	T	2: 122,527,160 (GRCm39)	L411H	probably damaging	Het
Slc44a5	C	T	3: 153,939,782 (GRCm39)		probably benign	Het
Slc4a3	C	T	1: 75,525,665 (GRCm39)	A255V	probably damaging	Het
Slc9b1	A	G	3: 135,088,593 (GRCm39)	N318S	possibly damaging	Het
Tcp11l2	A	T	10: 84,440,458 (GRCm39)	H287L	probably benign	Het
Tex10	C	T	4: 48,456,800 (GRCm39)	R637Q	probably benign	Het
Tnks2	T	A	19: 36,849,962 (GRCm39)	Y605N	probably damaging	Het
Topbp1	T	A	9: 103,227,037 (GRCm39)	N1490K	probably benign	Het
Ube4b	T	G	4: 149,442,034 (GRCm39)		probably benign	Het
Usp4	G	A	9: 108,225,228 (GRCm39)		probably benign	Het
Vezf1	A	T	11: 88,068,435 (GRCm38)		probably benign	Het
Vmn1r184	A	T	7: 25,966,500 (GRCm39)	D82V	probably damaging	Het

Other mutations in Pbrm1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00598:Pbrm1	APN	14	30,752,884 (GRCm39)	missense	probably damaging	1.00
IGL00648:Pbrm1	APN	14	30,774,240 (GRCm39)	missense	probably damaging	1.00
IGL00654:Pbrm1	APN	14	30,754,361 (GRCm39)	splice site	probably benign
IGL00674:Pbrm1	APN	14	30,840,733 (GRCm39)	missense	probably damaging	1.00
IGL00701:Pbrm1	APN	14	30,774,205 (GRCm39)	missense	probably damaging	1.00
IGL00850:Pbrm1	APN	14	30,809,576 (GRCm39)	missense	probably damaging	1.00
IGL01024:Pbrm1	APN	14	30,774,217 (GRCm39)	missense	probably damaging	1.00
IGL01924:Pbrm1	APN	14	30,804,561 (GRCm39)	missense	probably damaging	1.00
IGL02122:Pbrm1	APN	14	30,811,573 (GRCm39)	missense	probably damaging	0.97
IGL02390:Pbrm1	APN	14	30,754,467 (GRCm39)	missense	probably benign	0.00
IGL02675:Pbrm1	APN	14	30,828,244 (GRCm39)	missense	possibly damaging	0.85
IGL02936:Pbrm1	APN	14	30,783,470 (GRCm39)	missense	probably damaging	1.00
IGL02938:Pbrm1	APN	14	30,789,761 (GRCm39)	missense	probably damaging	1.00
IGL02997:Pbrm1	APN	14	30,783,508 (GRCm39)	missense	probably damaging	1.00
IGL03246:Pbrm1	APN	14	30,832,506 (GRCm39)	missense	probably benign	0.00
IGL03290:Pbrm1	APN	14	30,829,241 (GRCm39)	missense	probably damaging	1.00
IGL03372:Pbrm1	APN	14	30,806,976 (GRCm39)	missense	probably benign	0.04
IGL03386:Pbrm1	APN	14	30,772,049 (GRCm39)	missense	probably damaging	1.00
PIT4520001:Pbrm1	UTSW	14	30,789,818 (GRCm39)	missense	probably damaging	0.99
R0502:Pbrm1	UTSW	14	30,786,777 (GRCm39)	missense	probably benign	0.36
R0552:Pbrm1	UTSW	14	30,757,916 (GRCm39)	missense	probably damaging	1.00
R0558:Pbrm1	UTSW	14	30,807,016 (GRCm39)	splice site	probably null
R0561:Pbrm1	UTSW	14	30,757,948 (GRCm39)	missense	probably benign
R0835:Pbrm1	UTSW	14	30,789,536 (GRCm39)	missense	probably damaging	1.00
R1167:Pbrm1	UTSW	14	30,772,099 (GRCm39)	missense	probably damaging	1.00
R1209:Pbrm1	UTSW	14	30,840,809 (GRCm39)	missense	probably damaging	1.00
R1259:Pbrm1	UTSW	14	30,796,771 (GRCm39)	missense	probably damaging	1.00
R1321:Pbrm1	UTSW	14	30,789,459 (GRCm39)	missense	probably damaging	1.00
R1622:Pbrm1	UTSW	14	30,754,505 (GRCm39)	missense	probably benign	0.07
R1843:Pbrm1	UTSW	14	30,760,914 (GRCm39)	missense	probably damaging	1.00
R1870:Pbrm1	UTSW	14	30,828,132 (GRCm39)	missense	probably damaging	0.99
R2202:Pbrm1	UTSW	14	30,754,406 (GRCm39)	missense	possibly damaging	0.76
R2203:Pbrm1	UTSW	14	30,754,406 (GRCm39)	missense	possibly damaging	0.76
R2247:Pbrm1	UTSW	14	30,796,850 (GRCm39)	missense	probably damaging	1.00
R3237:Pbrm1	UTSW	14	30,754,432 (GRCm39)	missense	probably damaging	1.00
R4091:Pbrm1	UTSW	14	30,757,960 (GRCm39)	missense	probably benign	0.00
R4280:Pbrm1	UTSW	14	30,829,269 (GRCm39)	critical splice donor site	probably null
R4379:Pbrm1	UTSW	14	30,789,663 (GRCm39)	missense	probably damaging	1.00
R4381:Pbrm1	UTSW	14	30,747,513 (GRCm39)	missense	probably benign	0.02
R4816:Pbrm1	UTSW	14	30,832,405 (GRCm39)	missense	probably benign	0.32
R4939:Pbrm1	UTSW	14	30,783,580 (GRCm39)	missense	probably damaging	1.00
R4945:Pbrm1	UTSW	14	30,774,173 (GRCm39)	missense	probably damaging	0.97
R4958:Pbrm1	UTSW	14	30,796,784 (GRCm39)	missense	probably damaging	1.00
R5095:Pbrm1	UTSW	14	30,754,487 (GRCm39)	missense	probably benign	0.00
R5276:Pbrm1	UTSW	14	30,828,141 (GRCm39)	missense	probably damaging	0.99
R5387:Pbrm1	UTSW	14	30,804,567 (GRCm39)	missense	probably damaging	1.00
R5434:Pbrm1	UTSW	14	30,806,968 (GRCm39)	missense	probably damaging	0.96
R5476:Pbrm1	UTSW	14	30,754,476 (GRCm39)	missense	probably benign	0.00
R5522:Pbrm1	UTSW	14	30,811,520 (GRCm39)	missense	probably damaging	1.00
R5548:Pbrm1	UTSW	14	30,827,381 (GRCm39)	missense	probably damaging	1.00
R5605:Pbrm1	UTSW	14	30,757,949 (GRCm39)	missense	probably benign	0.20
R6089:Pbrm1	UTSW	14	30,809,542 (GRCm39)	missense	probably damaging	0.99
R6159:Pbrm1	UTSW	14	30,774,240 (GRCm39)	missense	possibly damaging	0.95
R6224:Pbrm1	UTSW	14	30,772,068 (GRCm39)	missense	probably benign	0.19
R6335:Pbrm1	UTSW	14	30,806,052 (GRCm39)	missense	probably damaging	1.00
R6499:Pbrm1	UTSW	14	30,783,466 (GRCm39)	missense	probably damaging	0.99
R6823:Pbrm1	UTSW	14	30,806,747 (GRCm39)	missense	probably damaging	1.00
R7002:Pbrm1	UTSW	14	30,786,777 (GRCm39)	missense	probably benign	0.36
R7021:Pbrm1	UTSW	14	30,789,773 (GRCm39)	missense	probably damaging	0.98
R7216:Pbrm1	UTSW	14	30,767,379 (GRCm39)	missense	possibly damaging	0.93
R7588:Pbrm1	UTSW	14	30,806,900 (GRCm39)	missense	probably damaging	0.99
R7828:Pbrm1	UTSW	14	30,752,848 (GRCm39)	missense	probably damaging	1.00
R8035:Pbrm1	UTSW	14	30,806,109 (GRCm39)	missense	probably damaging	1.00
R8188:Pbrm1	UTSW	14	30,789,773 (GRCm39)	missense	probably damaging	0.98
R8417:Pbrm1	UTSW	14	30,749,419 (GRCm39)	missense	possibly damaging	0.92
R8517:Pbrm1	UTSW	14	30,789,739 (GRCm39)	missense	probably benign	0.00
R9024:Pbrm1	UTSW	14	30,783,623 (GRCm39)	missense	probably damaging	1.00
R9294:Pbrm1	UTSW	14	30,806,760 (GRCm39)	nonsense	probably null
R9509:Pbrm1	UTSW	14	30,806,914 (GRCm39)	missense	probably damaging	1.00
R9713:Pbrm1	UTSW	14	30,828,123 (GRCm39)	missense	probably damaging	0.99
Z1088:Pbrm1	UTSW	14	30,832,411 (GRCm39)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- ACCTTTCCTCACCTCACAGATAGCA -3'
(R):5'- AGCAGTTTCTCTAGCCTCTTACCTGAT -3'

Sequencing Primer
(F):5'- gccatcgcttcagcctc -3'
(R):5'- TTTATGTTCGCATTTTCTGTTTATCC -3'

Posted On

2013-07-11