Mutagenetix > Incidental Mutation

Incidental Mutation 'R7202:Ahnak'

560410

Institutional Source

Beutler Lab

Gene Symbol

Ahnak

Ensembl Gene

ENSMUSG00000069833

Gene Name

AHNAK nucleoprotein

Synonyms

DY6, 1110004P15Rik, 2310047C17Rik

MMRRC Submission

045280-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.313) question?

Stock #

R7202 (G1)

Quality Score

225.009

Status

Validated

Chromosome

Chromosomal Location

8966648-9054278 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 8995163 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Asparagine at position 5482 (K5482N)

Ref Sequence

ENSEMBL: ENSMUSP00000090633 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092955] [ENSMUST00000092956]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000092955

SMART Domains

Protein: ENSMUSP00000090632
Gene: ENSMUSG00000069833

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000092956
AA Change: K5482N

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000090633
Gene: ENSMUSG00000069833
AA Change: K5482N

Domain	Start	End	E-Value	Type
low complexity region	2	13	N/A	INTRINSIC
PDZ	20	91	2.31e-5	SMART
internal_repeat_2	163	1515	5.22e-182	PROSPERO
internal_repeat_1	224	2314	N/A	PROSPERO
internal_repeat_2	1532	3028	5.22e-182	PROSPERO
internal_repeat_1	2660	5095	N/A	PROSPERO
low complexity region	5336	5353	N/A	INTRINSIC
low complexity region	5493	5504	N/A	INTRINSIC
low complexity region	5580	5600	N/A	INTRINSIC
low complexity region	5620	5636	N/A	INTRINSIC

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.7%
20x: 99.0%

Validation Efficiency

99% (74/75)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
PHENOTYPE: Mice homozygous for one knock-out allele exhibit decreased T cell proliferation and increased susceptibility to parasitic infection. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 74 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca14	T	C	7: 119,917,236 (GRCm39)	I1467T	probably damaging	Het
Abtb3	A	G	10: 85,223,629 (GRCm39)	E146G	unknown	Het
Adgrf3	T	A	5: 30,409,378 (GRCm39)	K38*	probably null	Het
Ahdc1	T	A	4: 132,789,198 (GRCm39)	C146*	probably null	Het
Arhgap23	C	T	11: 97,342,819 (GRCm39)	A367V	possibly damaging	Het
Arvcf	T	C	16: 18,223,948 (GRCm39)	S960P	probably damaging	Het
Asb14	C	A	14: 26,622,394 (GRCm39)	P74Q	probably benign	Het
Atad5	T	C	11: 79,980,601 (GRCm39)	V2A	probably damaging	Het
Baz2a	A	G	10: 127,954,428 (GRCm39)	I691M	possibly damaging	Het
Brca2	A	G	5: 150,455,819 (GRCm39)	T187A	probably benign	Het
Calr4	T	A	4: 109,101,254 (GRCm39)	N152K	possibly damaging	Het
Ccnb2	C	T	9: 70,318,128 (GRCm39)	A215T	probably damaging	Het
Cdh16	C	T	8: 105,340,780 (GRCm39)	D140N	unknown	Het
Ces1g	T	C	8: 94,029,595 (GRCm39)	T546A	probably benign	Het
Cfap74	G	T	4: 155,510,654 (GRCm39)		probably null	Het
Cfap91	T	C	16: 38,155,959 (GRCm39)	Y88C	probably benign	Het
Col5a1	G	T	2: 27,842,390 (GRCm39)	D422Y	unknown	Het
Cyp2c66	A	T	19: 39,130,348 (GRCm39)	Y61F	probably damaging	Het
Dnah12	G	A	14: 26,500,869 (GRCm39)		probably null	Het
Dnah6	A	G	6: 73,158,688 (GRCm39)		probably null	Het
Dop1a	T	G	9: 86,386,220 (GRCm39)		probably null	Het
Fam163a	A	G	1: 155,954,834 (GRCm39)	F106L	probably damaging	Het
Gfy	T	C	7: 44,827,596 (GRCm39)	T167A	probably benign	Het
Gm6525	A	T	3: 84,082,341 (GRCm39)	R87S	probably benign	Het
Gramd1c	C	A	16: 43,879,584 (GRCm39)	A19S	possibly damaging	Het
Herc2	T	C	7: 55,781,034 (GRCm39)	V1233A	probably damaging	Het
Hibch	G	A	1: 52,892,874 (GRCm39)		probably null	Het
Ibsp	A	T	5: 104,450,027 (GRCm39)	S9C	probably benign	Het
Il17ra	A	G	6: 120,452,572 (GRCm39)	I252V	probably benign	Het
Ino80	A	T	2: 119,204,918 (GRCm39)	M1536K	probably benign	Het
Ipo11	A	T	13: 107,012,078 (GRCm39)	L568Q	probably damaging	Het
Kcnu1	T	G	8: 26,409,609 (GRCm39)		probably null	Het
Kdm5b	T	G	1: 134,552,497 (GRCm39)	S1158A	probably benign	Het
Kmt2a	T	C	9: 44,759,012 (GRCm39)	T946A	probably benign	Het
Kmt2e	A	T	5: 23,697,292 (GRCm39)		probably benign	Het
Krba1	G	A	6: 48,389,261 (GRCm39)	V594M	probably damaging	Het
Lamb1	T	C	12: 31,374,314 (GRCm39)	L1559P	probably damaging	Het
Lig1	C	T	7: 13,025,175 (GRCm39)	P227S	probably benign	Het
Lims2	T	A	18: 32,090,017 (GRCm39)	D255E	probably benign	Het
Marchf3	C	T	18: 56,909,161 (GRCm39)	C208Y	probably benign	Het
Mei1	A	G	15: 81,976,843 (GRCm39)	E142G		Het
Melk	G	T	4: 44,351,106 (GRCm39)	R549L	probably benign	Het
Muc6	AGGCGCAGAAACCCTGGC	AGGC	7: 141,214,363 (GRCm39)		probably null	Het
Myorg	T	C	4: 41,498,268 (GRCm39)	Y454C	probably damaging	Het
Nae1	T	C	8: 105,250,215 (GRCm39)	Y226C	possibly damaging	Het
Nap1l1	T	C	10: 111,326,964 (GRCm39)	F175S	probably damaging	Het
Ndn	T	C	7: 61,998,709 (GRCm39)	L185P	probably damaging	Het
Ndst3	T	A	3: 123,465,388 (GRCm39)	I195F	possibly damaging	Het
Ndufaf1	A	T	2: 119,488,907 (GRCm39)	S206T	probably benign	Het
Nek10	C	A	14: 14,836,171 (GRCm38)	H131N	probably benign	Het
Obsl1	T	A	1: 75,466,360 (GRCm39)	D1456V	possibly damaging	Het
Or10a2	A	G	7: 106,673,448 (GRCm39)	N138D	probably benign	Het
Or10ak7	C	T	4: 118,791,215 (GRCm39)	V277I	probably benign	Het
Or52s6	T	A	7: 103,092,292 (GRCm39)	T13S	probably benign	Het
Otog	C	T	7: 45,937,474 (GRCm39)	L1728F	probably damaging	Het
Pcx	A	T	19: 4,652,361 (GRCm39)	M150L	possibly damaging	Het
Pole	A	G	5: 110,444,973 (GRCm39)	D443G	possibly damaging	Het
Prr14	G	T	7: 127,075,648 (GRCm39)	R552L	probably damaging	Het
Rasgrf1	T	G	9: 89,899,125 (GRCm39)	S1156A	possibly damaging	Het
Rfc4	T	A	16: 22,946,359 (GRCm39)		probably benign	Het
Rfx5	G	T	3: 94,866,272 (GRCm39)	A524S	unknown	Het
Ryr3	G	A	2: 112,596,664 (GRCm39)	P2497S	probably damaging	Het
Scg3	T	C	9: 75,590,992 (GRCm39)	T6A	probably benign	Het
Slc26a9	A	T	1: 131,690,526 (GRCm39)	D510V	possibly damaging	Het
Stpg3	A	G	2: 25,104,586 (GRCm39)	F10L	probably damaging	Het
Tmc5	T	A	7: 118,239,179 (GRCm39)	H357Q	possibly damaging	Het
Tmem40	A	T	6: 115,707,420 (GRCm39)	L253H	probably damaging	Het
Tmie	A	G	9: 110,696,632 (GRCm39)	V83A	probably damaging	Het
Uck2	A	T	1: 167,054,084 (GRCm39)	I218N	probably damaging	Het
Vtn	A	G	11: 78,391,626 (GRCm39)	D310G	possibly damaging	Het
Wdr49	A	T	3: 75,240,580 (GRCm39)	S430T	probably benign	Het
Wtip	A	G	7: 33,832,087 (GRCm39)	V133A	probably benign	Het
Zbtb9	T	A	17: 27,193,666 (GRCm39)	V357E	probably damaging	Het
Zfp953	G	A	13: 67,491,706 (GRCm39)	T82M	probably benign	Het

Other mutations in Ahnak

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00467:Ahnak	APN	19	8,984,587 (GRCm39)	missense	probably damaging	0.99
IGL00509:Ahnak	APN	19	8,987,315 (GRCm39)	missense	possibly damaging	0.94
IGL00539:Ahnak	APN	19	8,985,272 (GRCm39)	missense	possibly damaging	0.50
IGL00558:Ahnak	APN	19	8,981,671 (GRCm39)	missense	possibly damaging	0.93
IGL00567:Ahnak	APN	19	8,990,747 (GRCm39)	missense	probably benign	0.24
IGL00706:Ahnak	APN	19	8,991,094 (GRCm39)	nonsense	probably null
IGL00807:Ahnak	APN	19	8,985,886 (GRCm39)	missense	possibly damaging	0.92
IGL00870:Ahnak	APN	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
IGL01101:Ahnak	APN	19	8,990,251 (GRCm39)	intron	probably benign
IGL01118:Ahnak	APN	19	8,989,942 (GRCm39)	missense	probably damaging	1.00
IGL01288:Ahnak	APN	19	8,979,858 (GRCm39)	missense	possibly damaging	0.94
IGL01324:Ahnak	APN	19	8,980,396 (GRCm39)	missense	probably damaging	1.00
IGL01341:Ahnak	APN	19	8,989,067 (GRCm39)	missense	probably benign
IGL01541:Ahnak	APN	19	8,985,243 (GRCm39)	missense	possibly damaging	0.95
IGL01580:Ahnak	APN	19	8,980,203 (GRCm39)	missense	probably benign	0.02
IGL01595:Ahnak	APN	19	8,980,865 (GRCm39)	nonsense	probably null
IGL01746:Ahnak	APN	19	8,982,276 (GRCm39)	missense	possibly damaging	0.89
IGL01766:Ahnak	APN	19	8,977,482 (GRCm39)	missense	unknown
IGL01821:Ahnak	APN	19	8,989,482 (GRCm39)	missense	probably benign
IGL01913:Ahnak	APN	19	8,983,428 (GRCm39)	nonsense	probably null
IGL01934:Ahnak	APN	19	8,980,021 (GRCm39)	missense	probably damaging	1.00
IGL01940:Ahnak	APN	19	8,983,921 (GRCm39)	missense	probably benign	0.14
IGL01958:Ahnak	APN	19	8,992,273 (GRCm39)	missense	possibly damaging	0.59
IGL02145:Ahnak	APN	19	8,980,219 (GRCm39)	missense	probably benign	0.11
IGL02246:Ahnak	APN	19	8,985,632 (GRCm39)	missense	probably damaging	1.00
IGL02282:Ahnak	APN	19	8,983,351 (GRCm39)	missense	probably damaging	1.00
IGL02428:Ahnak	APN	19	8,992,197 (GRCm39)	missense	possibly damaging	0.83
IGL02442:Ahnak	APN	19	8,981,380 (GRCm39)	missense	probably damaging	1.00
IGL02474:Ahnak	APN	19	8,982,297 (GRCm39)	missense	probably benign	0.13
IGL02483:Ahnak	APN	19	8,980,672 (GRCm39)	missense	probably benign	0.01
IGL02616:Ahnak	APN	19	8,982,991 (GRCm39)	missense	probably benign	0.03
IGL02630:Ahnak	APN	19	8,989,441 (GRCm39)	missense	probably damaging	1.00
IGL02690:Ahnak	APN	19	8,989,948 (GRCm39)	nonsense	probably null
IGL02717:Ahnak	APN	19	8,979,751 (GRCm39)	missense	probably benign	0.00
IGL02721:Ahnak	APN	19	8,987,071 (GRCm39)	missense	probably benign	0.07
IGL02737:Ahnak	APN	19	8,981,957 (GRCm39)	missense	probably benign	0.17
IGL02850:Ahnak	APN	19	8,979,960 (GRCm39)	missense	probably benign	0.00
IGL03071:Ahnak	APN	19	8,989,282 (GRCm39)	missense	possibly damaging	0.63
IGL03072:Ahnak	APN	19	8,983,872 (GRCm39)	missense	probably benign	0.11
IGL03094:Ahnak	APN	19	8,980,911 (GRCm39)	missense	possibly damaging	0.64
IGL03140:Ahnak	APN	19	8,982,576 (GRCm39)	intron	probably benign
IGL03176:Ahnak	APN	19	8,979,813 (GRCm39)	missense	probably damaging	1.00
IGL03176:Ahnak	APN	19	8,985,530 (GRCm39)	missense	possibly damaging	0.56
IGL03189:Ahnak	APN	19	8,988,603 (GRCm39)	missense	possibly damaging	0.65
IGL03357:Ahnak	APN	19	8,986,689 (GRCm39)	intron	probably benign
IGL03371:Ahnak	APN	19	8,981,592 (GRCm39)	missense	possibly damaging	0.91
Eskimo	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
Nanook	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
Netsilik	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
IGL03097:Ahnak	UTSW	19	8,979,751 (GRCm39)	missense	probably benign	0.00
PIT4403001:Ahnak	UTSW	19	8,983,540 (GRCm39)	missense	possibly damaging	0.87
R0054:Ahnak	UTSW	19	8,989,420 (GRCm39)	missense	probably damaging	1.00
R0094:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R0110:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0141:Ahnak	UTSW	19	8,984,044 (GRCm39)	missense	probably damaging	1.00
R0166:Ahnak	UTSW	19	8,983,089 (GRCm39)	missense	probably damaging	1.00
R0309:Ahnak	UTSW	19	8,979,859 (GRCm39)	missense	probably damaging	1.00
R0368:Ahnak	UTSW	19	8,985,714 (GRCm39)	nonsense	probably null
R0386:Ahnak	UTSW	19	8,988,508 (GRCm39)	missense	possibly damaging	0.94
R0401:Ahnak	UTSW	19	8,992,480 (GRCm39)	missense	probably benign	0.24
R0415:Ahnak	UTSW	19	8,990,235 (GRCm39)	intron	probably benign
R0463:Ahnak	UTSW	19	8,986,771 (GRCm39)	intron	probably benign
R0469:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0470:Ahnak	UTSW	19	8,986,331 (GRCm39)	missense	probably benign	0.29
R0487:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R0487:Ahnak	UTSW	19	8,984,515 (GRCm39)	missense	probably benign	0.00
R0499:Ahnak	UTSW	19	8,977,628 (GRCm39)	splice site	probably benign
R0506:Ahnak	UTSW	19	8,986,492 (GRCm39)	missense	probably damaging	1.00
R0510:Ahnak	UTSW	19	8,995,596 (GRCm39)	nonsense	probably null
R0557:Ahnak	UTSW	19	8,979,308 (GRCm39)	missense	probably benign	0.10
R0570:Ahnak	UTSW	19	8,991,062 (GRCm39)	missense	probably damaging	1.00
R0610:Ahnak	UTSW	19	8,985,242 (GRCm39)	missense	probably benign	0.08
R0646:Ahnak	UTSW	19	8,990,766 (GRCm39)	nonsense	probably null
R0659:Ahnak	UTSW	19	8,992,366 (GRCm39)	missense	possibly damaging	0.60
R0791:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0792:Ahnak	UTSW	19	8,994,098 (GRCm39)	missense	probably benign	0.01
R0840:Ahnak	UTSW	19	8,982,427 (GRCm39)	missense	probably damaging	1.00
R0847:Ahnak	UTSW	19	8,983,797 (GRCm39)	nonsense	probably null
R0941:Ahnak	UTSW	19	8,987,278 (GRCm39)	missense	probably damaging	1.00
R0962:Ahnak	UTSW	19	8,990,212 (GRCm39)	intron	probably benign
R1017:Ahnak	UTSW	19	8,987,907 (GRCm39)	missense	probably damaging	0.99
R1037:Ahnak	UTSW	19	8,984,982 (GRCm39)	missense	probably benign	0.27
R1085:Ahnak	UTSW	19	8,990,489 (GRCm39)	missense	possibly damaging	0.50
R1113:Ahnak	UTSW	19	8,982,984 (GRCm39)	missense	probably benign	0.29
R1140:Ahnak	UTSW	19	8,981,609 (GRCm39)	missense	probably damaging	1.00
R1158:Ahnak	UTSW	19	8,991,290 (GRCm39)	missense	probably benign	0.00
R1218:Ahnak	UTSW	19	8,992,983 (GRCm39)	missense	probably damaging	1.00
R1225:Ahnak	UTSW	19	8,980,247 (GRCm39)	missense	probably damaging	1.00
R1245:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R1421:Ahnak	UTSW	19	8,992,995 (GRCm39)	missense	possibly damaging	0.95
R1447:Ahnak	UTSW	19	8,984,446 (GRCm39)	missense	probably damaging	0.98
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1464:Ahnak	UTSW	19	8,982,260 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1466:Ahnak	UTSW	19	8,993,239 (GRCm39)	missense	probably damaging	1.00
R1471:Ahnak	UTSW	19	8,990,296 (GRCm39)	intron	probably benign
R1507:Ahnak	UTSW	19	8,987,441 (GRCm39)	missense	probably damaging	1.00
R1521:Ahnak	UTSW	19	8,982,092 (GRCm39)	missense	probably benign	0.11
R1568:Ahnak	UTSW	19	8,979,739 (GRCm39)	missense	probably damaging	0.98
R1569:Ahnak	UTSW	19	8,981,458 (GRCm39)	missense	possibly damaging	0.78
R1616:Ahnak	UTSW	19	8,986,351 (GRCm39)	missense	possibly damaging	0.94
R1638:Ahnak	UTSW	19	8,986,813 (GRCm39)	missense	probably benign	0.01
R1680:Ahnak	UTSW	19	8,987,327 (GRCm39)	missense	probably benign	0.05
R1713:Ahnak	UTSW	19	8,989,173 (GRCm39)	missense	possibly damaging	0.95
R1722:Ahnak	UTSW	19	8,988,019 (GRCm39)	missense	probably damaging	0.99
R1771:Ahnak	UTSW	19	8,991,117 (GRCm39)	missense	probably benign	0.24
R1795:Ahnak	UTSW	19	8,979,802 (GRCm39)	missense	possibly damaging	0.79
R1823:Ahnak	UTSW	19	8,982,269 (GRCm39)	missense	probably damaging	0.99
R1842:Ahnak	UTSW	19	8,983,231 (GRCm39)	missense	probably damaging	0.99
R1854:Ahnak	UTSW	19	8,991,196 (GRCm39)	missense	possibly damaging	0.61
R1856:Ahnak	UTSW	19	8,979,412 (GRCm39)	missense	possibly damaging	0.86
R1886:Ahnak	UTSW	19	8,993,343 (GRCm39)	missense	probably damaging	0.98
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1888:Ahnak	UTSW	19	8,984,452 (GRCm39)	missense	probably damaging	1.00
R1912:Ahnak	UTSW	19	8,995,245 (GRCm39)	missense	probably damaging	1.00
R1913:Ahnak	UTSW	19	8,985,286 (GRCm39)	missense	probably damaging	0.99
R1942:Ahnak	UTSW	19	8,992,447 (GRCm39)	missense	probably damaging	0.98
R1987:Ahnak	UTSW	19	8,992,615 (GRCm39)	missense	probably damaging	1.00
R2006:Ahnak	UTSW	19	8,984,439 (GRCm39)	missense	probably damaging	1.00
R2013:Ahnak	UTSW	19	8,991,937 (GRCm39)	missense	probably damaging	0.98
R2014:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R2047:Ahnak	UTSW	19	8,991,664 (GRCm39)	missense	possibly damaging	0.67
R2048:Ahnak	UTSW	19	8,984,420 (GRCm39)	missense	probably damaging	0.99
R2060:Ahnak	UTSW	19	8,985,405 (GRCm39)	missense	probably benign	0.08
R2083:Ahnak	UTSW	19	8,988,921 (GRCm39)	missense	probably damaging	1.00
R2157:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R2167:Ahnak	UTSW	19	8,988,858 (GRCm39)	nonsense	probably null
R2208:Ahnak	UTSW	19	8,995,096 (GRCm39)	missense	probably benign	0.00
R2224:Ahnak	UTSW	19	8,990,355 (GRCm39)	intron	probably benign
R2268:Ahnak	UTSW	19	8,987,938 (GRCm39)	missense	possibly damaging	0.66
R2420:Ahnak	UTSW	19	8,986,620 (GRCm39)	missense	possibly damaging	0.89
R2426:Ahnak	UTSW	19	8,980,215 (GRCm39)	missense	possibly damaging	0.81
R2910:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2911:Ahnak	UTSW	19	8,989,018 (GRCm39)	missense	probably damaging	0.99
R2981:Ahnak	UTSW	19	8,977,512 (GRCm39)	missense	probably damaging	0.97
R3151:Ahnak	UTSW	19	8,987,308 (GRCm39)	missense	probably benign	0.12
R3155:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R3422:Ahnak	UTSW	19	8,984,116 (GRCm39)	missense	probably benign	0.05
R3422:Ahnak	UTSW	19	8,983,072 (GRCm39)	missense	probably benign	0.39
R3430:Ahnak	UTSW	19	8,984,322 (GRCm39)	missense	probably benign	0.42
R3433:Ahnak	UTSW	19	8,987,358 (GRCm39)	missense	probably benign	0.01
R3711:Ahnak	UTSW	19	8,985,262 (GRCm39)	missense	probably benign
R3723:Ahnak	UTSW	19	8,994,217 (GRCm39)	missense	possibly damaging	0.79
R3775:Ahnak	UTSW	19	8,986,387 (GRCm39)	missense	possibly damaging	0.91
R3858:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3859:Ahnak	UTSW	19	8,988,223 (GRCm39)	missense	possibly damaging	0.82
R3922:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3924:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R3926:Ahnak	UTSW	19	8,983,692 (GRCm39)	missense	probably benign	0.20
R4026:Ahnak	UTSW	19	8,988,663 (GRCm39)	missense	probably damaging	0.97
R4051:Ahnak	UTSW	19	8,991,691 (GRCm39)	missense	probably damaging	1.00
R4209:Ahnak	UTSW	19	8,979,964 (GRCm39)	missense	probably damaging	1.00
R4234:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R4237:Ahnak	UTSW	19	8,979,147 (GRCm39)	missense	probably benign	0.02
R4285:Ahnak	UTSW	19	8,994,203 (GRCm39)	nonsense	probably null
R4331:Ahnak	UTSW	19	8,993,184 (GRCm39)	missense	probably damaging	1.00
R4342:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R4430:Ahnak	UTSW	19	8,980,404 (GRCm39)	missense	probably benign	0.00
R4554:Ahnak	UTSW	19	8,992,294 (GRCm39)	missense	probably damaging	1.00
R4602:Ahnak	UTSW	19	8,988,189 (GRCm39)	missense	possibly damaging	0.66
R4612:Ahnak	UTSW	19	8,981,088 (GRCm39)	missense	probably benign	0.44
R4655:Ahnak	UTSW	19	8,986,065 (GRCm39)	missense	probably damaging	1.00
R4656:Ahnak	UTSW	19	8,982,219 (GRCm39)	missense	possibly damaging	0.80
R4700:Ahnak	UTSW	19	8,982,045 (GRCm39)	missense	probably benign	0.02
R4704:Ahnak	UTSW	19	8,989,622 (GRCm39)	intron	probably benign
R4704:Ahnak	UTSW	19	8,990,545 (GRCm39)	missense	probably damaging	0.99
R4705:Ahnak	UTSW	19	8,994,270 (GRCm39)	missense	probably benign	0.07
R4707:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	probably benign	0.03
R4732:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4733:Ahnak	UTSW	19	8,984,665 (GRCm39)	missense	probably damaging	1.00
R4778:Ahnak	UTSW	19	8,989,339 (GRCm39)	missense	possibly damaging	0.79
R4782:Ahnak	UTSW	19	8,989,863 (GRCm39)	intron	probably benign
R4832:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R4882:Ahnak	UTSW	19	8,983,261 (GRCm39)	missense	probably damaging	0.98
R4884:Ahnak	UTSW	19	8,990,118 (GRCm39)	intron	probably benign
R4895:Ahnak	UTSW	19	8,994,805 (GRCm39)	missense	probably benign	0.43
R4930:Ahnak	UTSW	19	8,988,331 (GRCm39)	missense	possibly damaging	0.79
R4951:Ahnak	UTSW	19	8,995,199 (GRCm39)	missense	probably damaging	1.00
R4968:Ahnak	UTSW	19	8,992,464 (GRCm39)	missense	probably damaging	1.00
R5026:Ahnak	UTSW	19	8,987,995 (GRCm39)	missense	possibly damaging	0.46
R5050:Ahnak	UTSW	19	8,989,822 (GRCm39)	intron	probably benign
R5073:Ahnak	UTSW	19	8,980,595 (GRCm39)	missense	probably benign	0.42
R5110:Ahnak	UTSW	19	8,992,123 (GRCm39)	missense	probably damaging	1.00
R5119:Ahnak	UTSW	19	8,991,008 (GRCm39)	missense	probably benign	0.00
R5128:Ahnak	UTSW	19	8,994,451 (GRCm39)	missense	probably damaging	1.00
R5139:Ahnak	UTSW	19	8,982,019 (GRCm39)	missense	probably damaging	1.00
R5150:Ahnak	UTSW	19	8,988,268 (GRCm39)	missense	possibly damaging	0.46
R5151:Ahnak	UTSW	19	8,994,933 (GRCm39)	missense	probably benign	0.03
R5165:Ahnak	UTSW	19	8,993,029 (GRCm39)	missense	possibly damaging	0.95
R5236:Ahnak	UTSW	19	8,978,048 (GRCm39)	missense	possibly damaging	0.92
R5361:Ahnak	UTSW	19	8,992,705 (GRCm39)	missense	possibly damaging	0.92
R5366:Ahnak	UTSW	19	8,994,099 (GRCm39)	missense	possibly damaging	0.65
R5387:Ahnak	UTSW	19	8,981,055 (GRCm39)	missense	probably damaging	1.00
R5396:Ahnak	UTSW	19	8,984,539 (GRCm39)	missense	probably damaging	0.99
R5583:Ahnak	UTSW	19	8,984,281 (GRCm39)	missense	probably damaging	0.99
R5587:Ahnak	UTSW	19	8,986,840 (GRCm39)	missense	possibly damaging	0.88
R5620:Ahnak	UTSW	19	8,990,458 (GRCm39)	nonsense	probably null
R5643:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5644:Ahnak	UTSW	19	8,988,021 (GRCm39)	missense	possibly damaging	0.66
R5657:Ahnak	UTSW	19	8,991,979 (GRCm39)	missense	probably damaging	0.99
R5688:Ahnak	UTSW	19	8,979,883 (GRCm39)	missense	probably benign	0.01
R5702:Ahnak	UTSW	19	8,979,204 (GRCm39)	missense	probably damaging	1.00
R5727:Ahnak	UTSW	19	8,994,111 (GRCm39)	missense	probably damaging	0.99
R5730:Ahnak	UTSW	19	8,987,617 (GRCm39)	missense	possibly damaging	0.81
R5755:Ahnak	UTSW	19	8,979,096 (GRCm39)	missense	probably benign	0.06
R5760:Ahnak	UTSW	19	8,990,926 (GRCm39)	missense	probably damaging	1.00
R5789:Ahnak	UTSW	19	8,979,685 (GRCm39)	missense	probably benign	0.00
R5790:Ahnak	UTSW	19	8,992,612 (GRCm39)	missense	probably damaging	0.99
R5795:Ahnak	UTSW	19	8,989,746 (GRCm39)	nonsense	probably null
R5808:Ahnak	UTSW	19	8,987,599 (GRCm39)	missense	possibly damaging	0.91
R5867:Ahnak	UTSW	19	8,987,416 (GRCm39)	missense	probably damaging	0.99
R5878:Ahnak	UTSW	19	8,985,706 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,995,575 (GRCm39)	missense	probably damaging	1.00
R5898:Ahnak	UTSW	19	8,991,131 (GRCm39)	missense	possibly damaging	0.63
R5912:Ahnak	UTSW	19	8,989,267 (GRCm39)	missense	probably damaging	0.99
R5935:Ahnak	UTSW	19	8,992,546 (GRCm39)	missense	possibly damaging	0.91
R5969:Ahnak	UTSW	19	8,993,949 (GRCm39)	missense	probably damaging	1.00
R5988:Ahnak	UTSW	19	8,986,711 (GRCm39)	intron	probably benign
R6000:Ahnak	UTSW	19	8,990,475 (GRCm39)	nonsense	probably null
R6005:Ahnak	UTSW	19	8,992,525 (GRCm39)	missense	possibly damaging	0.61
R6101:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6105:Ahnak	UTSW	19	8,981,463 (GRCm39)	missense	probably benign	0.20
R6116:Ahnak	UTSW	19	8,990,327 (GRCm39)	intron	probably benign
R6209:Ahnak	UTSW	19	8,989,930 (GRCm39)	missense	probably damaging	1.00
R6240:Ahnak	UTSW	19	8,990,947 (GRCm39)	missense	probably damaging	1.00
R6255:Ahnak	UTSW	19	8,985,389 (GRCm39)	missense	possibly damaging	0.95
R6263:Ahnak	UTSW	19	8,995,641 (GRCm39)	missense	probably benign	0.03
R6287:Ahnak	UTSW	19	8,992,367 (GRCm39)	missense	probably benign	0.02
R6296:Ahnak	UTSW	19	8,980,669 (GRCm39)	missense	probably damaging	0.99
R6315:Ahnak	UTSW	19	8,983,990 (GRCm39)	missense	probably damaging	0.99
R6328:Ahnak	UTSW	19	8,984,512 (GRCm39)	missense	probably benign	0.11
R6331:Ahnak	UTSW	19	8,983,989 (GRCm39)	missense	probably benign	0.18
R6355:Ahnak	UTSW	19	8,986,126 (GRCm39)	missense	probably benign	0.02
R6409:Ahnak	UTSW	19	8,986,938 (GRCm39)	missense	probably benign	0.31
R6567:Ahnak	UTSW	19	8,986,170 (GRCm39)	missense	probably benign	0.27
R6572:Ahnak	UTSW	19	8,985,340 (GRCm39)	missense	probably damaging	0.99
R6574:Ahnak	UTSW	19	8,994,411 (GRCm39)	missense	probably benign	0.04
R6590:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6620:Ahnak	UTSW	19	8,992,674 (GRCm39)	missense	possibly damaging	0.95
R6690:Ahnak	UTSW	19	8,986,945 (GRCm39)	missense	probably benign	0.29
R6731:Ahnak	UTSW	19	8,988,926 (GRCm39)	missense	possibly damaging	0.85
R6756:Ahnak	UTSW	19	8,984,925 (GRCm39)	missense	possibly damaging	0.59
R6846:Ahnak	UTSW	19	8,989,221 (GRCm39)	missense	possibly damaging	0.66
R6854:Ahnak	UTSW	19	8,992,599 (GRCm39)	missense	probably damaging	1.00
R6857:Ahnak	UTSW	19	9,014,532 (GRCm39)	nonsense	probably null
R6863:Ahnak	UTSW	19	8,989,729 (GRCm39)	intron	probably benign
R6876:Ahnak	UTSW	19	8,991,484 (GRCm39)	missense	probably damaging	0.99
R6958:Ahnak	UTSW	19	8,992,579 (GRCm39)	missense	possibly damaging	0.88
R7126:Ahnak	UTSW	19	8,979,723 (GRCm39)	missense	possibly damaging	0.61
R7181:Ahnak	UTSW	19	8,990,852 (GRCm39)	missense	probably damaging	1.00
R7183:Ahnak	UTSW	19	8,995,032 (GRCm39)	missense	probably damaging	1.00
R7235:Ahnak	UTSW	19	8,989,852 (GRCm39)	missense	unknown
R7241:Ahnak	UTSW	19	8,986,395 (GRCm39)	missense	possibly damaging	0.65
R7269:Ahnak	UTSW	19	8,983,981 (GRCm39)	missense	probably damaging	1.00
R7311:Ahnak	UTSW	19	8,979,507 (GRCm39)	missense	probably benign	0.04
R7311:Ahnak	UTSW	19	8,987,191 (GRCm39)	missense	possibly damaging	0.56
R7329:Ahnak	UTSW	19	8,979,156 (GRCm39)	missense	probably damaging	0.99
R7339:Ahnak	UTSW	19	8,985,529 (GRCm39)	missense	possibly damaging	0.75
R7390:Ahnak	UTSW	19	8,980,569 (GRCm39)	missense	probably benign	0.02
R7400:Ahnak	UTSW	19	8,991,977 (GRCm39)	missense	probably damaging	0.99
R7444:Ahnak	UTSW	19	8,984,787 (GRCm39)	missense	probably benign	0.08
R7483:Ahnak	UTSW	19	8,982,186 (GRCm39)	missense	probably damaging	1.00
R7498:Ahnak	UTSW	19	8,989,383 (GRCm39)	missense	probably benign	0.14
R7521:Ahnak	UTSW	19	8,979,715 (GRCm39)	missense	possibly damaging	0.89
R7522:Ahnak	UTSW	19	8,979,686 (GRCm39)	missense	probably benign	0.01
R7552:Ahnak	UTSW	19	8,984,188 (GRCm39)	missense	probably benign	0.18
R7563:Ahnak	UTSW	19	8,988,529 (GRCm39)	missense	probably damaging	0.99
R7565:Ahnak	UTSW	19	8,993,520 (GRCm39)	missense	probably benign	0.05
R7571:Ahnak	UTSW	19	8,978,150 (GRCm39)	nonsense	probably null
R7583:Ahnak	UTSW	19	8,983,457 (GRCm39)	missense	possibly damaging	0.90
R7600:Ahnak	UTSW	19	8,981,938 (GRCm39)	missense	possibly damaging	0.89
R7771:Ahnak	UTSW	19	8,992,411 (GRCm39)	missense	probably damaging	0.99
R7787:Ahnak	UTSW	19	8,986,679 (GRCm39)	missense	unknown
R7827:Ahnak	UTSW	19	8,982,708 (GRCm39)	nonsense	probably null
R7857:Ahnak	UTSW	19	8,984,832 (GRCm39)	missense	probably damaging	0.97
R7916:Ahnak	UTSW	19	8,983,196 (GRCm39)	missense	possibly damaging	0.66
R7939:Ahnak	UTSW	19	8,991,448 (GRCm39)	nonsense	probably null
R7959:Ahnak	UTSW	19	8,988,013 (GRCm39)	missense	possibly damaging	0.46
R7962:Ahnak	UTSW	19	8,990,164 (GRCm39)	missense	unknown
R7979:Ahnak	UTSW	19	8,988,796 (GRCm39)	missense	probably damaging	1.00
R8006:Ahnak	UTSW	19	8,989,447 (GRCm39)	missense	possibly damaging	0.79
R8013:Ahnak	UTSW	19	8,986,699 (GRCm39)	missense	unknown
R8033:Ahnak	UTSW	19	8,981,074 (GRCm39)	missense	probably benign	0.10
R8124:Ahnak	UTSW	19	8,984,487 (GRCm39)	missense	probably damaging	0.99
R8125:Ahnak	UTSW	19	8,989,240 (GRCm39)	missense	possibly damaging	0.95
R8129:Ahnak	UTSW	19	8,977,464 (GRCm39)	start codon destroyed	not run
R8151:Ahnak	UTSW	19	8,982,043 (GRCm39)	missense	possibly damaging	0.59
R8190:Ahnak	UTSW	19	8,979,619 (GRCm39)	missense	probably benign	0.01
R8221:Ahnak	UTSW	19	8,987,800 (GRCm39)	nonsense	probably null
R8241:Ahnak	UTSW	19	8,984,659 (GRCm39)	missense	probably benign	0.15
R8244:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8248:Ahnak	UTSW	19	8,979,310 (GRCm39)	missense	probably damaging	1.00
R8261:Ahnak	UTSW	19	8,982,817 (GRCm39)	missense	probably damaging	1.00
R8330:Ahnak	UTSW	19	8,987,026 (GRCm39)	missense	possibly damaging	0.86
R8380:Ahnak	UTSW	19	8,995,219 (GRCm39)	missense	probably benign	0.05
R8407:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8409:Ahnak	UTSW	19	8,993,037 (GRCm39)	missense	probably benign	0.44
R8463:Ahnak	UTSW	19	8,986,113 (GRCm39)	missense	probably benign	0.07
R8511:Ahnak	UTSW	19	8,989,719 (GRCm39)	missense	unknown
R8528:Ahnak	UTSW	19	8,985,092 (GRCm39)	missense	probably damaging	1.00
R8549:Ahnak	UTSW	19	8,988,847 (GRCm39)	missense	probably damaging	1.00
R8674:Ahnak	UTSW	19	8,983,360 (GRCm39)	missense	probably damaging	0.98
R8716:Ahnak	UTSW	19	8,986,438 (GRCm39)	missense	probably damaging	1.00
R8722:Ahnak	UTSW	19	8,990,710 (GRCm39)	nonsense	probably null
R8751:Ahnak	UTSW	19	8,987,509 (GRCm39)	missense	probably damaging	1.00
R8752:Ahnak	UTSW	19	8,992,901 (GRCm39)	missense	probably damaging	1.00
R8783:Ahnak	UTSW	19	8,988,837 (GRCm39)	missense	probably damaging	1.00
R8844:Ahnak	UTSW	19	8,984,254 (GRCm39)	missense	probably damaging	1.00
R8859:Ahnak	UTSW	19	8,984,567 (GRCm39)	missense	probably damaging	1.00
R8882:Ahnak	UTSW	19	8,978,106 (GRCm39)	missense	probably damaging	1.00
R8907:Ahnak	UTSW	19	8,986,452 (GRCm39)	missense	probably benign	0.24
R8938:Ahnak	UTSW	19	8,989,099 (GRCm39)	missense	probably benign	0.00
R8975:Ahnak	UTSW	19	8,990,101 (GRCm39)	missense	probably damaging	1.00
R8983:Ahnak	UTSW	19	8,981,477 (GRCm39)	missense	possibly damaging	0.75
R9017:Ahnak	UTSW	19	8,987,487 (GRCm39)	missense	probably damaging	1.00
R9027:Ahnak	UTSW	19	8,984,617 (GRCm39)	missense	possibly damaging	0.94
R9081:Ahnak	UTSW	19	8,985,890 (GRCm39)	missense	possibly damaging	0.81
R9104:Ahnak	UTSW	19	8,987,711 (GRCm39)	missense	probably benign	0.01
R9112:Ahnak	UTSW	19	8,987,149 (GRCm39)	missense	probably damaging	0.98
R9145:Ahnak	UTSW	19	8,992,287 (GRCm39)	missense	probably benign	0.38
R9189:Ahnak	UTSW	19	8,988,247 (GRCm39)	missense	possibly damaging	0.92
R9221:Ahnak	UTSW	19	8,989,943 (GRCm39)	missense	probably damaging	1.00
R9261:Ahnak	UTSW	19	8,993,503 (GRCm39)	missense	possibly damaging	0.63
R9299:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9325:Ahnak	UTSW	19	8,991,257 (GRCm39)	missense	probably benign	0.12
R9337:Ahnak	UTSW	19	8,989,824 (GRCm39)	intron	probably benign
R9340:Ahnak	UTSW	19	8,994,411 (GRCm39)	missense	probably benign	0.04
R9351:Ahnak	UTSW	19	8,985,232 (GRCm39)	missense	probably damaging	1.00
R9416:Ahnak	UTSW	19	8,990,266 (GRCm39)	missense	unknown
R9462:Ahnak	UTSW	19	8,981,299 (GRCm39)	missense	probably damaging	0.96
R9469:Ahnak	UTSW	19	8,988,225 (GRCm39)	missense	probably damaging	1.00
R9485:Ahnak	UTSW	19	8,979,438 (GRCm39)	missense	probably benign	0.16
R9503:Ahnak	UTSW	19	8,987,458 (GRCm39)	missense	probably damaging	1.00
R9524:Ahnak	UTSW	19	9,014,617 (GRCm39)	missense
R9534:Ahnak	UTSW	19	8,980,976 (GRCm39)	missense	probably benign	0.20
R9598:Ahnak	UTSW	19	8,981,149 (GRCm39)	missense	probably benign	0.42
R9611:Ahnak	UTSW	19	8,989,162 (GRCm39)	missense	probably damaging	0.99
R9624:Ahnak	UTSW	19	8,989,846 (GRCm39)	missense	unknown
R9649:Ahnak	UTSW	19	8,985,786 (GRCm39)	nonsense	probably null
R9683:Ahnak	UTSW	19	8,984,719 (GRCm39)	missense	possibly damaging	0.94
R9691:Ahnak	UTSW	19	8,989,090 (GRCm39)	missense	possibly damaging	0.49
R9712:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9712:Ahnak	UTSW	19	8,984,392 (GRCm39)	small deletion	probably benign
R9713:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9715:Ahnak	UTSW	19	8,984,393 (GRCm39)	small deletion	probably benign
R9725:Ahnak	UTSW	19	8,991,607 (GRCm39)	missense	probably damaging	1.00
R9725:Ahnak	UTSW	19	8,981,533 (GRCm39)	missense	probably benign	0.44
R9747:Ahnak	UTSW	19	8,987,541 (GRCm39)	missense	possibly damaging	0.49
R9798:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
RF007:Ahnak	UTSW	19	8,990,965 (GRCm39)	missense	possibly damaging	0.45
X0021:Ahnak	UTSW	19	8,990,983 (GRCm39)	missense	probably damaging	0.99
X0027:Ahnak	UTSW	19	8,989,401 (GRCm39)	missense	probably damaging	1.00
Z1088:Ahnak	UTSW	19	8,993,446 (GRCm39)	missense	probably damaging	0.99
Z1176:Ahnak	UTSW	19	8,986,220 (GRCm39)	missense	probably damaging	0.97
Z1177:Ahnak	UTSW	19	8,994,832 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TCTGGAAAAGTAACATTCCCCAAG -3'
(R):5'- CATCACTGAAGGAGTTGGAGC -3'

Sequencing Primer
(F):5'- CAAGATGAAGATCCCTAAGTTTACC -3'
(R):5'- CGTGGCTTCTTACTTTTAAATAGGG -3'

Posted On

2019-06-26